- 作 者: "zheng liu"
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Partial and radical cystectomy provides equivalent oncologic outcomes in bladder cancer when combined with adequate lymph node dissection: A population-based studyUrologic Oncology: Seminars and Original Investigations (IF 2.954) Pub Date : 2023-03-23 ,DOI:10.1016/j.urolonc.2023.02.004Gongwei Long, Zhiquan Hu, Zheng Liu, Zhangqun Ye, Shaogang Wang, Dongwen Wang, Chunguang YangPurpose To compare the oncologic outcomes of bladder cancer (BCa) patients after partial cystectomy (PC) or radical cystectomy (RC) combined with lymph node dissection (LND). Methods Relevant data from BCa patients who had >3 lymph nodes (LNs) removed were retrieved from the Surveillance, Epidemiology, and End Results (SEER) database. Different thresholds of LN count in LND were tested to eliminate ...
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Sononeoperfusion: a new therapeutic effect to enhance tumour blood perfusion using diagnostic ultrasound and microbubblesCancer Imaging (IF 5.605) Pub Date : 2023-03-23 ,DOI:10.1186/s40644-023-00545-yNajiao Tang, Jiawei Tang, Junhui Tang, Qiong Zhu, Xiaoxiao Dong, Yi Zhang, Ningshan Li, Zheng LiuHypoperfusion or resultant hypoxia in solid tumours is a main reason for therapeutic resistance. Augmenting the blood perfusion of hypovascular tumours might improve both hypoxia and drug delivery. Cavitation is known to result in microstreaming and sonoporation and to enhance drug diffusion into tumours. Here, we report the ability to enhance both tumour blood perfusion and doxorubicin (Dox) delivery ...
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Gate-Induced Trans-Dimensionality of Carrier Distribution in Bilayer Lateral Heterosheet of MoS2 and WS2 for Semiconductor Devices with Tunable FunctionalityACS Applied Nano Materials (IF 6.14) Pub Date : 2023-03-22 ,DOI:10.1021/acsanm.2c05561Mina Maruyama, Nanami Ichinose, Yanlin Gao, Zheng Liu, Ryo Kitaura, Susumu OkadaUsing the metal–organic chemical vapor deposition technique, we synthesized a bilayer lateral heterostucture of MoS2 and WS2, each of which layers consist of alternately arranged nanostrips of MoS2 and WS2. Transmission electron microscope images exhibit a checked pattern contrast, reflecting the three distinct interlayer metal arrangements of Mo/Mo, W/Mo (Mo/W), and W/W stacking. Theoretical calculations ...
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Full-Period Quantum Phase EstimationPhysical Review Letters (IF 9.185) Pub Date : 2023-03-22 ,DOI:10.1103/physrevlett.130.120802Li-Zheng Liu, Yue-Yang Fei, Yingqiu Mao, Yi Hu, Rui Zhang, Xu-Fei Yin, Xiao Jiang, Li Li, Nai-Le Liu, Feihu Xu, Yu-Ao Chen, Jian-Wei PanQuantum sensing can provide the superior sensitivity for sensing a physical quantity beyond the shot-noise limit. In practice, however, this technique has been limited to the issues of phase ambiguity and low sensitivity for small-scale probe states. Here, we propose and demonstrate a full-period quantum phase estimation approach by adopting the Kitaev’s phase estimation algorithm to eliminate the ...
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Memory CD4+T cell profile is associated with unfavorable prognosis in IgG4-related disease: Risk stratification by machine-learningClinical Immunology (IF 10.19) Pub Date : 2023-03-21 ,DOI:10.1016/j.clim.2023.109301Yuxue Nie, Zheng Liu, Wei Cao, Yu Peng, Hui Lu, Ruijie Sun, Jingna Li, Linyi Peng, Jiaxin Zhou, Yunyun Fei, Mengtao Li, Xiaofeng Zeng, Taisheng Li, Wen ZhangIgG4-related disease (IgG4-RD) is a chronic immune-mediated disease with heterogeneity. In this study, we used machine-learning approaches to characterize the immune cell profiles and to identify the heterogeneity of IgG4-RD. The XGBoost model discriminated IgG4-RD from HCs with an area under the receiver operating characteristic curve of 0.963 in the testing set. There were two clusters of IgG4-RD ...
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Functional characterization of five developmental signaling network genes in the white-backed planthopper: potential application for pest managementPest Management Science (IF 4.462) Pub Date : 2023-03-21 ,DOI:10.1002/ps.7464Xuan-Zheng Liu, Huan Guo, Gui-Jun Long, Yun-Feng Ma, Lang-Lang Gong, Meng-Qi Zhang, J. Joe Hull, Youssef Dewer, Li-Wei Liu, Ming He, Peng HeThe white-backed planthopper (WBPH, Sogatella furcifera) is a major rice pest that exhibits condition dependent wing dimorphisms – a macropterous (long wing) form and a brachypterous (short wing) form. Although, the gene cascade that regulates wing development and dimorphic differentiation has been largely defined, the utility of these genes as targets for pest control has yet to be fully explored ...
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Catalyst-Substrate Helical Character Matching Determines the Enantioselectivity in the Ishihara-Type Iodoarenes Catalyzed Asymmetric Kita-Dearomative SpirolactonizationJournal of the American Chemical Society (IF 16.383) Pub Date : 2023-03-20 ,DOI:10.1021/jacs.2c13295Hanliang Zheng, Liu Cai, Ming Pan, Muhammet Uyanik, Kazuaki Ishihara, Xiao-Song XueCatalyst design has traditionally focused on rigid structural elements to prevent conformational flexibility. Ishihara’s elegant design of conformationally flexible C2-symmetric iodoarenes, a new class of privileged organocatalysts, for the catalytic asymmetric dearomatization (CADA) of naphthols is a notable exception. Despite the widespread use of the Ishihara catalysts for CADAs, the reaction mechanism ...
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Structural characteristics of the SARS-CoV-2 Omicron lineages BA.1 and BA.2 virionsSignal Transduction and Targeted Therapy (IF 38.104) Pub Date : 2023-03-20 ,DOI:10.1038/s41392-023-01385-9Xiaoyu Ma, Yanqun Wang, Yuanzhu Gao, Yiliang Wang, An Yan, Jiantao Chen, Lu Zhang, Peiyi Wang, Jincun Zhao, Zheng Liu
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Orthogonally Activatable CRISPR-Cas13d Nanoprodrug to Reverse Chemoresistance for Enhanced Chemo-Photodynamic TherapyChemical Science (IF 9.969) Pub Date : 2023-03-20 ,DOI:10.1039/d3sc00020fZheng Liu, Zhiyuan Feng, Mohan Chen, Jiayin Zhan, Rong Wu, Yang Shi, Yunsheng Xue, Ran Liu, Jun-Jie Zhu, Jingjing ZhangOrthogonal therapy that combines CRISPR-based gene editing and prodrug-based chemotherapy is a promising approach to combat multidrug-resistant cancer. However, its potency to precisely regulate different therapeutic modalities in vivo is limited due to the lack of integrated platform with high spatiotemporal resolution. Taking advantage of CRISPR technology, Pt(IV)-based prodrug and orthogonal emissive ...
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Four anti-inflammatory aromadendrane sesquiterpenoid fucosides and other constituents from Pittosporum glabratum var. neriifoliumPhytochemistry Letters (IF 1.873) Pub Date : 2023-03-16 ,DOI:10.1016/j.phytol.2023.03.008Bai-Tong Sha, Rong Huang, Qiang-Guo Zhang, Sheng-Nan Guan, Jia-Qi Ding, Xin-Zheng Liu, Xiu-Yun ZhangPhytochemical investigation of Pittosporum glabratum var. neriifolium EtOH extract led to four aromadendrane sesquiterpenoid glycosides, including one new, pitglabroside A (1), together with eight other kinds of constituents (5－12). Their structures were elucidated by comprehensive spectroscopic analysis, including 1D and 2D NMR, HRESIMS and ECD spectra. Four sesquiterpenoid glycosides (1－4) were evaluated ...
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Pan-cancer analysis identifies PD-L2 as a tumor promotor in the tumor microenvironmentFrontiers in Immunology (IF 8.786) Pub Date : 2023-03-16 ,DOI:10.3389/fimmu.2023.1093716Jingfang Lv, Zheng Jiang, Junhu Yuan, Meng Zhuang, Xu Guan, Hengchang Liu, Yefeng Yin, Yiming Ma, Zheng Liu, Hongying Wang, Xishan WangBackgroundProgrammed cell death protein 1 (PD-1) receptor has two ligands,programmed death-ligand 1 (PD-L1) and PD-L2. When compared with PD-L1, PD-L2 has not received much attention, and its role remains unclear.MethodsThe expression profiles of pdcd1lg2 (PD-L2-encoding gene) mRNA and PD-L2 protein were analyzed using TCGA, ICGC, and HPA databases. Kaplan-Meier and Cox regression analyses were used ...
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The association of pregnancy with disease progression in patients previously treated for differentiated thyroid cancer: A propensity score-matched retrospective cohort studymedRxiv - Surgery Pub Date : 2023-03-16 ,DOI:10.1101/2023.03.15.23287341Xin Li, Wu-Cai Xiao, Fang Mei, Rui Shan, Shi-Bing Song, Bang-Kai Sun, He-Ling Bao, Jing Chen, Zheng Liu, Chun-Hui Yuan
IMPORTANCE Differentiated thyroid cancer (DTC) is increasingly common in women of reproductive age. However, whether pregnancy increases the risk of progression/recurrence of DTC after treatment remains controversial due to the effect of confounding. OBJECTIVE To assess the effect of pregnancy on structural or biochemical progression in patients previously treated for DTC in a retrospective cohort
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Biomarkers for Lipid and Albumin Metabolism in Hospitalized Patients with Underlying Diseases and Community-Acquired Pneumonia Caused by Bacterial or SARS-CoV-2 InfectionJournal of Inflammation Research (IF 4.631) Pub Date : 2023-03-15 ,DOI:10.2147/jir.s399921Zheng Liu, Qian Wang, Hui Wang, Jing Li, Ying Yuan, Guo-zhen Yi
Background: To look at the differences and similarities in albumin and lipid metabolism in non-severe COVID-19 infection, non-severe community-acquired pneumonia, and severe community pneumonia with underlying diseases, as well as the relationship between albumin and lipid metabolism and inflammatory mediators. Methods: This retrospective analysis comprised 253 individuals with bacterial pneumonia
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Study on Semisolid Rheo-Diecasting Process, Microstructure and Mechanical Properties of Mg-6Al-1Ca-0.5Sb Alloy with High Solid FractionInternational Journal of Metalcasting (IF 2.263) Pub Date : 2023-03-15 ,DOI:10.1007/s40962-023-01001-0Yuanhao Gu, Feng Wang, Jian Jiao, Zhi Wang, Le Zhou, Pingli Mao, Zheng LiuRheo-diecasting with high solid fraction is a new die casting process developed in recent years. In order to promote the application of this process in magnesium alloys, taking the test bar castings as the research object in the experiment, the commercial simulation software, FLOW-3D, was used to simulate the effects of the semisolid rheo-diecasting process parameters on the test bar air entrainment ...
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Comprehensive Analysis of bHLH Transcription Factors in Ipomoea aquatica and Its Response to Anthocyanin BiosynthesisInternational Journal of Molecular Sciences (IF 6.208) Pub Date : 2023-03-15 ,DOI:10.3390/ijms24065652Zheng Liu, Xiaoai Fu, Hao Xu, Yuxin Zhang, Zhidi Shi, Guangzhen Zhou, Wenlong Bao
The basic helix-loop-helix (bHLH) proteins compose one of the largest transcription factor (TF) families in plants, which play a vital role in regulating plant biological processes including growth and development, stress response, and secondary metabolite biosynthesis. Ipomoea aquatica is one of the most important nutrient-rich vegetables. Compared to the common green-stemmed I. aquatica, purple-stemmed
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Edge effect reduction of high-resolution PET detectors using LYSO and GAGG phoswich crystals.Physics in Medicine & Biology (IF 4.174) Pub Date : 2023-03-15 ,DOI:10.1088/1361-6560/acbde1Zheng Liu,Samuel Mungai,Ming Niu,Zhonghua Kuang,Ning Ren,Xiaohui Wang,Ziru Sang,Yongfeng YangObjective. Small-animal positron emission tomography (PET) is a powerful preclinical imaging tool in animal model studies. The spatial resolution and sensitivity of current PET scanners developed for small-animal imaging need to be improved to increase the quantitative accuracy of preclinical animal studies. This study aimed to improve the identification capability of edge scintillator crystals of ...
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Two Antenna-Enriched Carboxylesterases Mediate Olfactory Responses and Degradation of Ester Volatiles in the German Cockroach Blattella germanicaJournal of Agricultural and Food Chemistry (IF 5.895) Pub Date : 2023-03-15 ,DOI:10.1021/acs.jafc.2c08488Yun-Feng Ma, Lang-Lang Gong, Meng-Qi Zhang, Xuan-Zheng Liu, Huan Guo, J. Joe Hull, Gui-Jun Long, Hong Wang, Youssef Dewer, Fan Zhang, Ming He, Peng HeInsects have evolved an extremely sensitive olfactory system that is essential for a series of physiological and behavioral activities. Some carboxylesterases (CCEs) comprise a major subfamily of odorant-degrading enzymes (ODEs) playing a crucial role in odorant signal inactivation to maintain the odorant receptor sensitivity. In this study, 93 CCEs were annotated in the genome of the German cockroach ...
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An Experimental StudyJournal of Ultrasound in Medicine (IF 2.754) Pub Date : 2023-03-14 ,DOI:10.1002/jum.16212Lei Yao, Tingting Luo, Guoliang Yang, Jiabei Yin, Hui Li, Zheng LiuThe objective of this study was to investigate the treatment effects of acoustic droplet vaporization (ADV) on tumors. ...
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Fracture study of glass with bubbles: Multiscale finite element method and experimental factsMaterialia Pub Date : 2023-03-14 ,DOI:10.1016/j.mtla.2023.101746Yangyang Cai, Shenhou Li, Kangjia Hu, Qianying Zhu, Zheng Liu, Keqian Gong, Yong ZhangSealing glass will inevitably generate bubbles during manufacturing processes. According to the test results of mechanical properties and micromorphology, porosity is likely to be pivotal in controlling the mechanical behaviour of glass. A multiscale finite element model of the extended finite element method (XFEM) coupled with a representative volume element (RVE) was established to elucidate the ...
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Pregnancy and the prognosis of patients previously treated for differentiated thyroid cancer: a systematic review and meta-analysismedRxiv - Otolaryngology Pub Date : 2023-03-14 ,DOI:10.1101/2023.03.11.23287150Rui Shan, Xin Li, Wu-Cai Xiao, Jing Chen, Fang Mei, Shi-Bing Song, Bang-Kai Sun, Zheng Liu
IMPORTANCE Differentiated thyroid cancer (DTC) is commonly diagnosed in women of child-bearing age, but whether pregnancy influences the prognosis of DTC remained controversial. OBJECTIVE This systematic review and meta-analysis aimed to summarize and appraise the existing evidence of the impact of pregnancy on the prognosis of patients previously treated for DTC. DATA SOURCES We searched PubMed, Embase
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Characteristics and emissions of isoprene and other non-methane hydrocarbons in the Northwest Pacific Ocean and responses to atmospheric aerosol deposition.The Science of the total environment Pub Date : 2023-03-14 ,DOI:10.1016/j.scitotenv.2023.162808Ying-Cui Wu,Xu-Xu Gao,Hong-Hai Zhang,Yong-Zheng Liu,Jian Wang,Feng Xu,Gui-Ling Zhang,Zhao-Hui ChenField investigations in the Northwest Pacific Ocean were carried out to determine the distributions of marine and atmospheric non-methane hydrocarbons (NMHCs), sources and environmental effects. We also conducted deck incubation experiments to investigate the effects of atmospheric aerosol deposition on NMHCs production. The marine NMHCs displayed an increasing trend from the South Equatorial Current ...
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Improving bowel preparation for colonoscopy with a smartphone application driven by artificial intelligencenpj Digital Medicine (IF 15.357) Pub Date : 2023-03-14 ,DOI:10.1038/s41746-023-00786-yDan-Feng Zhang, Hui-Li Wu, Pei-Yao Fu, Li Feng, Kun Zhuang, Zi-Han Geng, Kun-Kun Li, Xiao-Hong Zhang, Bo-Qun Zhu, Wen-Zheng Qin, Sheng-Li Lin, Zhen Zhang, Tian-Yin Chen, Yuan Huang, Xiao-Yue Xu, Jing-Zheng Liu, Shuo Wang, Wei Zhang, Quan-Lin Li, Ping-Hong ZhouOptimal bowel preparation is a prerequisite for a successful colonoscopy; however, the rate of inadequate bowel preparation remains relatively high. In this study, we establish a smartphone app that assesses patient bowel preparation using an artificial intelligence (AI)-based prediction system trained on labeled photographs of feces in the toilet and evaluate its impact on bowel preparation quality ...
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Study on catalytic gasification of pine wood with cerium loaded dolomite based clay ceramicsJournal of Fuel Chemistry and Technology Pub Date : 2023-03-13 ,DOI:10.1016/s1872-5813(22)60066-5Yong-hong NIU, Xiang-ru QIAN, Zheng LIU, Yi-ke LIWith dolomite as the main aggregate, a clay ceramic carrier was prepared by one-step powder sintering method. After being impregnated with Ce and calcined, a Ce loaded dolomite based (Ce-Dol) clay ceramic catalyst was prepared, which was used for the catalytic gasification of pine wood. The influence of the addition amount of Ce, steam flow rate, gasification temperature and other parameters on the ...
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Hydrothermal evolution and gold precipitation mechanism of the Hekou gold deposit, North China Craton: Insights from pyrite texture, composition and in situ S isotopeOre Geology Reviews (IF 3.714) Pub Date : 2023-03-13 ,DOI:10.1016/j.oregeorev.2023.105387Zheng Liu, Pei Ni, Guo-Guang Wang, Yue-Qiao Zhang, Zhong-Lie Sheng, Shun-Lin Zhang, Ming-Sen Fan, Zi-Hao ZhaoPyrite, as one of the most important Au carriers, can well document ore-forming processes. In this study, we select the Hekou gold deposit (HKGD), a newly discovered deposit in the North China Craton (NCC), to rebuild its ore-forming process and gold precipitation mechanism with pyrite. The gold-bearing pyrite was used to perform a combined micro-textural petrography, elemental and S isotope analyses ...
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Ion current rectification in asymmetric nanochannels: effects of nanochannel shape and surface chargeInternational Journal of Heat and Mass Transfer (IF 5.431) Pub Date : 2023-03-12 ,DOI:10.1016/j.ijheatmasstransfer.2023.124038Nan Qiao, Zhe Zhang, Zheng Liu, Wei Lu, Changzheng LiIon current rectification (ICR) in nanochannels has attracted increasing attention for its great potential in the applications of ionic circuits and biological sensors. Herein, the influence of nanochannel shape and surface charge on the ion transport and ICR performance of asymmetric nanochannels was numerically investigated. Firstly, three asymmetric nanochannels with different shapes (bullet, conical ...
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Effect of aging temperature on microstructure and mechanical properties of a novel Ti-6121 alloyJournal of Alloys and Compounds (IF 6.371) Pub Date : 2023-03-11 ,DOI:10.1016/j.jallcom.2023.169612Jianwei Chen, Le Wang, Qunbo Fan, Zhuoyue Sang, Yao Xu, Changhao Wang, Jiahao Yao, Zhiming Zhou, Liu Yang, Zheng Liu, Jinliang Gao, Heyong FengThe effect of heat treatment on the microstructure and mechanical properties of a novel α + β Ti-6.2Al-0.8V-2.25Mo-1.2Cr-0.5Si (wt%) alloy was investigated in this paper. Microstructure and crystalline structure of the alloys after different solution and aging treatments were identified by scanning electron microscopy (SEM) and X-ray diffraction (XRD). The results indicated that a multi-scale microstructure ...
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A co-evolutionary algorithm with elite archive strategy for generating diverse high-quality satellite range schedulesComplex & Intelligent Systems (IF 6.7) Pub Date : 2023-03-10 ,DOI:10.1007/s40747-023-01008-4Minghui Xiong, Wei Xiong, Zheng Liu
Satellite range scheduling, a multi-constrained combinatorial optimization problem, is crucial to guaranteeing the normal operation and application of onboard satellites. Traditional methods are dedicated to finding one optimal schedule, having ignored the problem may process multiple high-quality schedules. To provide a set of alternative schedules while maintaining the solution quality, we propose
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Semi-supervised machinery health assessment framework via temporal broad learning system embedding manifold regularization with unlabeled dataExpert Systems with Applications (IF 8.665) Pub Date : 2023-03-09 ,DOI:10.1016/j.eswa.2023.119824Yudong Cao, Minping Jia, Xiaoli Zhao, Xiaoan Yan, Zheng LiuIn the era of industrial big data, data-driven methods based on deep learning have made a splash in the field of mechanical PHM. However, the performance of deep learning models is limited by the depth of networks while previous supervised learning methods can only be applied to a small amount of labeled data while most of data acquired in the field are unlabeled, resulting in overfitting and low generalization ...
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Advances and trends in meningioma research over the last decade: A scientometric and visual analysisFrontiers in Oncology (IF 5.738) Pub Date : 2023-03-08 ,DOI:10.3389/fonc.2023.1112018Tingbao Zhang, Yu Feng, Kui Liu, Zheng Liu
ObjectiveWe conducted a scientometric and visual analysis of meningioma studies in the past ten years and discussed the current status and trends of meningioma research to provide a reference basis for conducting relevant clinical practice or research.MethodA search of the topic of meningioma in the Web of Science Core Collection database was conducted for January 2012-December 2021. The scientometric
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A novel rare variant of CNPY3 from familial NMOSD impairs the TLR-mediated immune responseJournal of Neuroimmunology (IF 3.221) Pub Date : 2023-03-08 ,DOI:10.1016/j.jneuroim.2023.578065Yongxin Mo, Shisi Wang, Yanyu Chang, Xiaobo Sun, Zheng Liu, Ping Sun, Yan Xu, Xiaofen Zhong, Lisheng PengToll-like receptors (TLRs) are a class of proteins that play essential roles in innate and adaptive immune responses. Recently, accumulating evidence has demonstrated that impairments in the TLR signalling pathway contribute to the development and progression of neuroimmune diseases, such as neuromyelitis optica spectrum disorder (NMOSD). However, the cellular and molecular mechanisms are still largely ...
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