- 作 者: ( "zaoying li" OR "zao-ying li" )
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Mir-485-5p on the Morphology and Function of Cardiovascular System.Cellular and Molecular Biology Pub Date : 2022-05-22 ,DOI:10.14715/cmb/2022.68.1.15Delai Zhang,Qian Nie,Yanru Liu,Zaoying Li,Wen Xie,Li Jiang
Cardiovascular disease is a global problem that seriously endangers human health and life. At present, hypertension is considered to be a polygenic disease caused by the interaction of environmental factors and genetic factors. Various environmental factors have been proved to promote the occurrence and development of cardiovascular disease. MicroRNA (miR), as an essential gene regulatory factor in
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Effectiveness of Acupuncture on Urinary Retention: A Meta-AnalysisEvidence-based Complementary and Alternative Medicine (IF 2.65) Pub Date : 2021-09-29 ,DOI:10.1155/2021/2500282Chengwen Zheng, Zaoying Li, Haizhen Lu, Yi Zhou
Objectives. This study aimed to evaluate the safety and efficacy of acupuncture in the treatment of urinary retention (UR). Methods. Randomized controlled trials investigating the effectiveness of acupuncture in the treatment of UR were identified by searching seven comprehensive databases (Cochrane Library, PubMed, Embase, China National Knowledge Infrastructure, Wanfang Database, China Science and
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Methylene violet 3RAX-conjugated porphyrin for photodynamic therapy: synthesis, DNA photocleavage, and cell study†RSC Advances (IF 4.036) Pub Date : 2018-01-24 ,DOI:10.1039/c7ra13176cSi Yao,Yunman Zheng,Lijun Jiang,Chen Xie,Fengshou Wu,Chi Huang,Xiong Zhang,Ka-Leung Wong,Zaoying Li,Kai Wang
A methylene violet 3RAX-conjugated porphyrin has been designed and synthesized as a potential photosensitizer in photodynamic therapy because of its high DNA binding constant and the efficacy in inhibiting cancer cells with subcellular localization.
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Synthesis, singlet oxygen generation, photocytotoxicity and subcellular localization of azobisporphyrins as potentially photodynamic therapeutic agents in vitro cell studyJournal of Porphyrins and Phthalocyanines (IF 1.914) Pub Date : 2017-03-30 ,DOI:10.1142/s1088424617500201Yunman Zheng, Sizhe Zhu, Lijun Jiang, Fengshou Wu, Chi Huang, Zaoying Li, Ka-Leung Wong, Zebin Xu, Kai WangThree azobisporphyrins (Por1, Por2 and Por3) were synthesized by coupling two molecules of (4-nitrophenyl/pyridyl) porphyrins in the presence of KOH/butanol. The structures of porphyrins were confirmed by UV, IR, NMR and mass spectra and elemental analysis. With tetraphenylporphyrin (H2TPP) as a control, the singlet oxygen (1O[Formula: see text] generation of porphyrins was evaluated through 1,3-d ...
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Synthesis, structural characterization and photophysical studies of luminescent Cu(I) heteroleptic complexes based on dipyridylamineJournal of Photochemistry and Photobiology A: Chemistry (IF 5.141) Pub Date : 2015-12-14 ,DOI:10.1016/j.jphotochem.2015.12.003Fengshou Wu, Hongbo Tong, Kai Wang, Zheng Wang, Zaoying Li, Xunjin Zhu, Wai-Yeung Wong, Wai-Kwok WongNeutral mononuclear Cu(I) complexes based on 2,2′-dipyridylamine (dpa), formulated as [Cu(dpa)X(PPh3)] (X = Cl (A4), Br (A5), I (A6)), monocationic mononuclear Cu(I) complexes with counterion BF4−, i.e. [Cu(dpa)(PPh3)2](BF4) (A1), Cu(dpa)(DPEphos)(BF4) (A2) and [Cu(dpa)(Binap)](BF4) (A3), where DPEphos = bis [2-(diphenylphosphino) phenyl] ether, Binap = 2,2′-bis(diphenylphosphino)-1,1′-binaphthyl, ...
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Photocytotoxicity, cellular uptake and subcellular localization of amidinophenylporphyrins as potential photodynamic therapeutic agents: An in vitro cell studyBioorganic & Medicinal Chemistry Letters (IF 2.94) Pub Date : 2015-08-28 ,DOI:10.1016/j.bmcl.2015.08.072Sizhe Zhu,Fengshou Wu,Kai Wang,Yunman Zheng,Zaoying Li,Xiulan Zhang,Wai-Kwok WongThe cell-based studies of 5, 10, 15, 20-Tetrakis (4-amidinophenyl) porphyrin (Por1), its Zn complex (Por2) and amidinophenyl bisporphyrin (Por3) were carried out to examine their photocytotoxicity, cellular uptake and sub-cellular localization with human nasopharyngeal carcinoma cell (HK-1), using 5, 10, 15, 20-Tetrakis (N-methyl-4-pyridyl) porphyrin (H2TMPyP) as a reference. These porphyrins showed ...
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Water-soluble porphyrin-phosphonate conjugates as potential photodynamic therapy photosensitizersJournal of Porphyrins and Phthalocyanines (IF 1.914) Pub Date : 2015-08-13 ,DOI:10.1142/s1088424615500789Yunguo Lu, Zhihang Chen, Bingqiong Yu, Kun Yan, Zaoying LiTwo novel water-soluble porphyrin-phosphonate conjugates were synthesized and characterized. Although both conjugates showed significant potential in photodynamic therapy, the variety of their structure induced the obvious differences in the binding manner with calf thymus DNA, the cytotoxicity and the cellular sublocalization. ...
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Design and synthesis of binuclear Co-salen catalysts for the hydrolytic kinetic resolution of epoxidesCatalysis Communications (IF 3.51) Pub Date : 2015-05-10 ,DOI:10.1016/j.catcom.2015.05.006Fengshou Wu,Kai Wang,Zaoying Li,Xunjin ZhuThree binuclear Co(III)-salen complexes have been synthesized based on a series of hydrophilic cyclic frameworks with different ring sizes. The catalytic performance of Co-salen complexes have further been evaluated in the hydrolytic kinetic resolution of racemic epoxides. And kinetic studies reveal that the binuclear Co-salen catalysts show a higher reactivity and better enantioselectivity in comparison ...
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Phosphorescent Cu(i) complexes based on bis(pyrazol-1-yl-methyl)-pyridine derivatives for organic light-emitting diodes†Journal of Materials Chemistry C (IF 8.067) Pub Date : 2014-10-23 ,DOI:10.1039/c4tc01885kFengshou Wu,Jie Li,Hongbo Tong,Zaoying Li,Chihaya Adachi,Adam Langlois,Pierre D. Harvey,Li Liu,Wai-Yeung Wong,Wai-Kwok Wong,Xunjin ZhuMononuclear Cu(I) complexes based on bis(pyrazol-1-yl-methyl)-pyridine derivatives and ancillary triphenylphosphine have been prepared and characterized by 1H NMR, mass spectroscopy and single-crystal X-ray analysis. The thermogravimetric analysis shows that the complexes exhibit high thermal stability. The electronic absorption spectra display two features in the regions of 230–260 and 290–350 nm ...
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A white phosphorescent coordination polymer with Cu2I2 alternating units linked by benzo-18-crown-6†Dalton Transactions (IF 4.569) Pub Date : 2014-05-13 ,DOI:10.1039/c4dt01070aFengshou Wu,Hongbo Tong,Zaoying Li,Wang Lei,Li Liu,Wai-Yeung Wong,Wai-Kwok Wong,Xunjin ZhuA new approach has been illustrated for the development of stable, efficient, and environmentally “friendly” white phosphorescent materials. Under mild conditions, a new one-dimensional coordination polymer has been prepared from benzo-18-crown-6 with CuI in the presence of KI, which is capable of emitting direct white light in the solid state. ...
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Morphological characterization of amidinophenylporphyrins interacting with DNA by photo irradiationChinese Chemical Letters (IF 8.455) Pub Date : 2013-11-01 ,DOI:10.1016/j.cclet.2013.07.018Kai Wang, Shuai-Hua Song, Yun-Man Zheng, Zao-Ying LiAbstract 5,10,15,20-Tetrakis(4-amidinophenyl)porphyrin (Por 1), its Zn complex (Por 2) and amidinophenyl bispophyrin (Por 3) interacting with calf thymus DNA were investigated by scanning electron microscopy (SEM) and the shape and size of the porphyrin–DNA complexes were observed after photo irradiation. The results showed that the shape and size of DNA had significant differences with blank group ...
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Synthesis and Structure of a Novel Alkynyl-Containing Disulfide Compound as Cathode Materials for Secondary Lithium BatteriesSynthetic Communications (IF 1.937) Pub Date : 2013-10-11 ,DOI:10.1080/00397911.2013.789526Zuxi Jin, Yunguo Lu, Shixi Li, Zaoying LiAbstract A novel alkynyl-containing disulfide compound, 5,8-dihydro-1H,4H-2,3,6,7-tetrathia-anthracen (TMSEDTTA), was synthesized. The structures of the target compound and the intermediates have been identified by 1H NMR, 13C NMR, mass spectrometry, Fourier-transform infrared, Raman spectra, x-ray photoelectron spectroscopy, and elemental analysis. In addition, the structure of (Z)-(1,2-dibromo-2-(2 ...
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Synthesis and properties of novel phenylethynyl-containing organodisulfide as cathode material for secondary lithium batteriesJournal of Applied Electrochemistry (IF 2.384) Pub Date : 2013-07-09 ,DOI:10.1007/s10800-013-0576-8Zuxi Jin, Hai Zhong, Shixi Li, Zaoying LiA novel phenylethynyl-containing conjugative organodisulfide compound 9-trimethylsilane ethynyl-5,8-dihydro-lH,4H-2,3,6,7-tetrathia-anthracene (TMSEDTTA) was synthesized by a facile preparation method, characterized by elemental analysis, Fourier transform infrared spectroscopy (FT-IR), Raman spectrum, X-ray photoelectron spectroscopy (XPS), and thermogravimetric analysis (TGA), and was tested as cathode ...
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Morphological characterization of amidinophenylporphyrins interacting with DNA by photo irradiationChinese Chemical Letters (IF 8.455) Pub Date : 2013 ,DOI:10.1016/j.cclet.2013.07.018Kai Wang, Shuai-Hua Song, Yun-Man Zheng, Zao-Ying Li5,10,15,20-Tetrakis(4-amidinophenyl)porphyrin (Por 1), its Zn complex (Por 2) and amidinophenyl bispophyrin (Por 3) interacting with calf thymus DNA were investigated by scanning electron microscopy (SEM) and the shape and size of the porphyrin–DNA complexes were observed after photo irradiation. The results showed that the shape and size of DNA had significant differences with blank group by virtue ...
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Fluorescent Properties of the Amidinophenylporphyrins Interacting with DNAChinese Journal of Chemistry (IF 5.56) Pub Date : 2012-02-29 ,DOI:10.1002/cjoc.201100564Kai Wang,Tian Li,Faquan Yu,Yunman Zheng,Wai-Kwok Wong,Daniel W. J. Kwong,Zaoying Li5,10,15,20‐Tetrakis(4‐amidinolphenyl)porphyrin, its Zn complex and amidinolphenyl bispophyrin interacting with calf thymus DNA were investigated by fluorescence emission spectra and fluorescence life time measurements were also shown. The binding modes of these compounds were recorded and lifetimes of luminescence were measured as a function of the nature to understand the interaction with DNA. The ...
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A new phosphonamidate as flame retardant additive in electrolytes for lithium ion batteriesJournal of Power Sources (IF 9.794) Pub Date : 2011-09-09 ,DOI:10.1016/j.jpowsour.2011.09.012Jianlin Hu,Zuxi Jin,Hai Zhong,Hui Zhan,Yunhong Zhou,Zaoying LiA new phosphonamidate, bis(N,N-diethyl)(2-methoxyethoxy)methylphosphonamidate (DEMEMPA) has been synthesized as N-P collaborative flame retardant additive in electrolytes for lithium ion batteries (LIBs). It is found that adding 10 vol.% of DEMEMPA to 0.9 M LiPF6/EC/DMC can significantly inhibit the burning of electrolytes and provide a wide electrochemical window. Further studies indicate that the ...
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Dipyrrolylquinoxaline-bridged hydrazones: a new class of chemosensors for copper(II)Journal of Inclusion Phenomena and Macrocyclic Chemistry (IF 1.925) Pub Date : 2011-03-22 ,DOI:10.1007/s10847-011-9941-6Qian-ni Guo, Cheng Zhong, Yun-guo Lu, Chuang Shi, Zao-ying LiNovel 2,3-bis(1H-pyrrol-2-yl)quinoxaline-functionalized hydrazones were prepared and characterized as new chemosensors for copper(II) ion. The binding properties of the compounds 4, 5, 6 and 7 for cations were examined by UV–vis, fluorescence spectroscopy, and linear sweep voltammetric experiments (LSV). The results indicate that a 1:1 stoichiometric complex is formed between compound 4 (or 5, 6, 7) ...
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A novel class of Cd(ii), Hg(ii) turn-on and Cu(ii), Zn(ii) turn-off Schiff basefluorescent probes†Dalton Transactions (IF 4.569) Pub Date : 2010-11-01 ,DOI:10.1039/c0dt00737dYuan Hu,Qian-qian Li,Hua Li,Qian-ni Guo,Yun-guo Lu,Zao-ying LiN,N′-((5,5′-(Quinoxaline-2,3-diyl)bis(1H-pyrrole-5,2-diyl))bis(methanylylidene))bis(4-methoxyaniline) 4 and N,N′-((5,5′-(quinoxaline-2,3-diyl)-bis(1H-pyrrole-5,2-diyl))bis(methanylylidene))dianiline 5 have been prepared and structurally characterized. The X-ray crystal structures of compounds 4 and 4a have been determined. These compounds displayed good sensitivity toward transition metal ions with ...
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An Easy Assembled, Click-Generated Macrocyclic Chromoionophores as Mercury(II) SensorsLetters in Organic Chemistry (IF 0.797) Pub Date : 2010-09-30 ,DOI:10.2174/157017810793362307Yun-Guo Lu, Zao-Ying Li, Albert W.M. Lee and Wing-Hong ChanExploiting click reaction as the key step, azo-coupled macrocyclic colorimetric chemosensors 4a and 4c were synthesized for metal ion sensing. Among metal ions examined, only Hg2+ can induce color change from orange to pale yellow detectable by the naked-eye for both sensors. The bind mode of the complex was established by spectrophotometric and NMR titrations. ...
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Synthesis and Characterization of β-Cyclodextrin Bonded Metal PorphyrinsChinese Journal of Chemistry (IF 5.56) Pub Date : 26 AUG 201 ,DOI:10.1002/cjoc.20020200420Zao-Ying Li, Cong Li, Jia-Feng LiReactions of 5-(p-aminophenyl)-10,15,20-triphenyl porphyrin (1) with Ru3(CO)12 or M(OCOCH3)2 (M= Ni, Mn) afforded metalloporphyrins (4–6), respectively. 6-Deoxy-6-iodo-β-cyclodextrin (2) and mono(6-O-trifluoromethanesulfonyl) permethylated β-cyclodextrin (3) reacted with complexes 4–6 to give β-cyclodextrin bonded metal porphyrins (7–9) and permethylated β-cydodextrin bonded metal porphyrins (10–12) ...
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Two genuine supramolecular isomers exhibiting hierarchical resemblance and distinction†CrystEngComm (IF 3.756) Pub Date : 2010-07-07 ,DOI:10.1039/c0ce00163eRong Peng,Mian Li,Shi-Ren Deng,Zao-Ying Li,Dan LiTwo supramolecular isomers based on CuCN and 3,4-bis(4-pyridinesulfanylmethyl)thiophene exhibited conformational, topological, catenane and optical isomerism within tectonic, molecular and supramolecular levels, respectively. At the material level, the two isomeric compounds displayed diverse photoluminescence, emitting at 517 nm and 553 nm, respectively, in the solid state at room temperature. ...
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Interaction between novel porphyrin-dextran nanoparticles and human serum albuminJournal of Porphyrins and Phthalocyanines (IF 1.914) Pub Date : 2010-05-05 ,DOI:10.1142/s1088424610001969Zhi Zhang, Qian-ni Guo, Yun-guo Lu, Tao Jia, Kun Yan, Zao-ying LiA novel porphyrin-dextran coated Fe3O4 nanoparticle (5) was designed and synthesized. The structure of 5 was confirmed by IR, UV-vis and inductively coupled plasma atomic emission spectrometry, and dynamic laser scattering (DLS); magnetic property was measured by a vibrating sample magnetometer (VSM). The interaction between compound 5 and human serum albumin (HSA) was investigated through UV-vis absorbance ...
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Appending zinc tetraphenylporphyrin with an amine receptor at β-pyrrolic carbon for designing a selective histamine chemosensorSupramolecular Chemistry (IF 2.23) Pub Date : 2010-01-18 ,DOI:10.1080/10610270903377349Qian-Ni Guo, Zao-Ying Li, Wing-Hong Chan, Kai-Chung Lau, Maxwell J. CrossleyAdopting the rarely used β-functionalisation strategy in porphyrin-based sensor design, an amine receptive site is appended onto the zinc(II) porphyrin molecular framework affording a ditopic chemosensor 4. The assembled chemosensor interacts selectively with histamine in toluene via a ‘two-site’ binding mode. Association constant of the complex evaluated from the respective UV–vis spectra is found ...
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Synthesis and in vitro and in vivo evaluation of manganese(III) porphyrin–dextran as a novel MRI contrast agentBioorganic & Medicinal Chemistry Letters (IF 2.94) Pub Date : 2009-10-04 ,DOI:10.1016/j.bmcl.2009.10.003Zhi Zhang,Rui He,Kun Yan,Qian-ni Guo,Yun-guo Lu,Xu-xia Wang,Hao Lei,Zao-ying Li5-(4-Aminophenyl)-10,15,20-tris(4-sulfonatophenyl) manganese(III) porphyrin conjugated with dextran was synthesized. Its potential of being used as a tumor-targeting magnetic resonance imaging contrast agent was evaluated in vitro and in vivo. The results demonstrated that the compound has a longitudinal relaxivity (R1) higher than Gd-DTPA, low cytotoxicity and binding specificity to tumor cell membrane ...
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Poly(tetrahydrobenzodithiophene): High discharge specific capacity as cathode material for lithium batteriesJournal of Power Sources (IF 9.794) Pub Date : 2009-05-20 ,DOI:10.1016/j.jpowsour.2009.05.015Lizhi Zhan,Zhiping Song,Ning Shan,Jingyu Zhang,Jing Tang,Hui Zhan,Yunhong Zhou,Zaoying Li,Caimao ZhanA novel thioether containing conjugative polymer, poly(tetrahydrobenzodithiophene) (PTBDT), with high discharge specific capacity as the cathode material for lithium batteries, has been synthesized chemically. The polymer has been characterized by elemental analysis, X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and thermogravimetric ...
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Synthesis, Characterization, Singlet-Oxygen Photogeneration, DNA Photocleavage and Two-Photon-Absorption Properties of Some (4-Cyanophenyl)porphyrinsEuropean Journal of Inorganic Chemistry (IF 2.551) Pub Date : 2009-03-01 ,DOI:10.1002/ejic.200801047Kai Wang, Chun-Ting Poon, Wai-Kwok Wong, Wai-Yeung Wong, Chun Y. Choi, Daniel W. J. Kwong, Heng Zhang, Zao-Ying LiA series of (4-cyanophenyl)porphyrins have been prepared and structurally characterized by 1H NMR, IR and UV/Vis spectroscopy, mass spectrometry, and elemental analysis. The relative singlet-oxygen quantum yields, two-photon absorption cross-sections and DNA photocleavage activities of these porphyrins were measured. The results show that (4-cyanophenyl)porphyrins with a properly designed hydrophobic/hydrophilic ...
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Binding of cationic porphyrin to human serum albumin studied using comprehensive spectroscopic methodsJournal of Pharmaceutical Sciences Pub Date : 2009-01-01 ,DOI:10.1002/jps.21413Bo Zhou, Zhi Zhang, Yue Zhang, Ran Li, Qi Xiao, Yi Liu, ZaoYing LiThe interaction between cationic porphyrin, a potential valuable anti-tumor and antibiotic drug, and human serum albumin (HSA) was investigated using spectroscopy methods. The binding constants were obtained using fluorescence quenching method (K(SV) = (3.24 +/- 0.29) x 10(4) M(-1)) and surface plasmon resonance (SPR) spectroscopy (K(A) = (6.287 +/- 0.407) x 10(4) M(-1)). The association rate constant ...
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Binding of cationic porphyrin to human serum albumin studied using comprehensive spectroscopic methods.Journal of Pharmaceutical Sciences Pub Date : 2009 Jan ,DOI:10.1002/jps.21413Bo Zhou,Zhi Zhang,Yue Zhang,Ran Li,Qi Xiao,Yi Liu,ZaoYing LiThe interaction between cationic porphyrin, a potential valuable anti-tumor and antibiotic drug, and human serum albumin (HSA) was investigated using spectroscopy methods. The binding constants were obtained using fluorescence quenching method (K(SV) = (3.24 +/- 0.29) x 10(4) M(-1)) and surface plasmon resonance (SPR) spectroscopy (K(A) = (6.287 +/- 0.407) x 10(4) M(-1)). The association rate constant ...
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