- 作 者: ( "lijuan gu" OR "li-juan gu" )
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Bow-and-arrow sign on point-of-care ultrasound for diagnosis of pacemaker lead-induced heart perforation: A case report and literature review.World Journal of Clinical Cases (IF 1.534) Pub Date : 2023-03-06 ,DOI:10.12998/wjcc.v11.i7.1615Ni Chen,Guang-Xian Miao,Liang-Qin Peng,Yun-Hang Li,Juan Gu,Ying He,Tao Chen,Xiao-Yun Fu,Zhou-Xiong Xing
BACKGROUND Pacemaker lead-induced heart perforation is a rare but life-threatening complication of pacemaker implantation, and timely diagnosis remains a challenge for clinicians. Here, we report a case of pacemaker lead-induced cardiac perforation rapidly diagnosed by a "bow-and-arrow" sign on point-of-care ultrasound (POCUS). CASE SUMMARY A 74-year-old Chinese woman who had undergone permanent pacemaker
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ATG5 Knockdown Attenuates Ischemia‒Reperfusion Injury by Reducing Excessive Autophagy-Induced FerroptosisTranslational Stroke Research (IF 6.8) Pub Date : 2022-12-16 ,DOI:10.1007/s12975-022-01118-0Hua Zhu, Yi Zhong, Ran Chen, Lei Wang, Yuntao Li, Zhihong Jian, Lijuan Gu, Xiaoxing XiongAutophagy has been described to be both protective and pathogenic in cerebral ischemia/reperfusion (I/R) injury. The underlying association between autophagy and ferroptosis in ischemic stroke has not yet been clearly investigated. The purpose of this study was to explore the role of autophagy-related gene 5 (ATG5) in experimental ischemic stroke. After injection of ATG5 shRNA lentivirus, mice underwent ...
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NLRP3 inflammasome deficiency attenuates cerebral ischemia-reperfusion injury by inhibiting ferroptosisBrain Research Bulletin (IF 3.715) Pub Date : 2022-11-23 ,DOI:10.1016/j.brainresbull.2022.11.016Zhuo Wang, Yina Li, Yingze Ye, Hua Zhu, Jing Zhang, Huijuan Wang, Jiaxi Lei, Lijuan Gu, Liying Zhan
Background The role of ferroptosis in ischemic stroke has been hotly debated recently, but the mechanism is not clearly clarified. It has been reported that the NLRP3 inflammasome is essential for the progression of ischemic stroke. Whether the ferroptosis after ischemic stroke mediated by the activation of NLRP3 inflammasome is still not reported. In this study, we investigated the effect of NLRP3
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Effects of inflammation and oxidative stress on postoperative delirium in cardiac surgeryFrontiers in Cardiovascular Medicine (IF 5.846) Pub Date : 2022-11-22 ,DOI:10.3389/fcvm.2022.1049600Yi Pang, Yuntao Li, Yonggang Zhang, Hongfa Wang, Junhui Lang, Liang Han, He Liu, Xiaoxing Xiong, Lijuan Gu, Xiaomin Wu
The past decade has witnessed unprecedented medical progress, which has translated into cardiac surgery being increasingly common and safe. However, complications such as postoperative delirium remain a major concern. Although the pathophysiological changes of delirium after cardiac surgery remain poorly understood, it is widely thought that inflammation and oxidative stress may be potential triggers
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Prostate primary intravascular large B-cell lymphoma: A case reportUrology Case Reports Pub Date : 2022-11-02 ,DOI:10.1016/j.eucr.2022.102276Lijuan Gu, Menghui Li, Guizhen Tong, Wei Wei, Yonghong Fan, Yongzhe Zhao
Intravascular large B-cell lymphoma (IVLBCL) is a distinct subtype of extranodal diffuse large B-cell lymphoma (DLBCL) and mainly affects elderly population characterized by selective infiltration of neoplastic cells within the lumina of small vessels. Prostate primary IVLBCL is extremely rare. Herein we present a case of a 76-year-old male patient who was admitted with symptoms of severe lower urinary
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Manipulating Trapped Nanobubbles Moving and Coalescing with Surface NanobubblesLangmuir (IF 4.331) Pub Date : 2022-10-13 ,DOI:10.1021/acs.langmuir.2c02593Dayong Li, Juan Gu, Yong Li, Ziqun Zhang, Yutong JiTrapped nanobubbles are observed nucleating at nanopits on a pitted substrate, while surface nanobubbles are usually formed on the smooth solid surface in water. In this work, trapped nanobubbles and surface nanobubbles were captured by a tapping-mode atomic force microscope (AFM) on a nanopitted substrate based on the temperature difference method. A single trapped nanobubble was manipulated to change ...
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First Report of Clonostachys rosea Causing rot of Morchella sextelata in Anhui Province, China.Plant Disease (IF 4.614) Pub Date : 2022-10-09 ,DOI:10.1094/pdis-08-22-1794-pdnYiwen Fu,Xi Xu,Honghui Wu,Lili Li,Jiajia Wang,Yuqing Sun,Lijuan Gu,Qiang Yu
Morel mushroom (Morchella spp.) is a valuable mushroom, which has extremely high nutritional and economic value. In the early March of 2022, a serious rot disease was observed on approximately 30% fruiting bodies at an M. esculenta farm of Suzhou City, Anhui province, China. A white mold-like hyphae was initially present on the pileus, which then gradually spread to the whole fruiting body, eventually
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APOL4, a Novel Immune-Related Prognostic Biomarker for GliomaJournal of Clinical Medicine (IF 4.964) Pub Date : 2022-09-29 ,DOI:10.3390/jcm11195765Hua Zhu, Xinyao Hu, Shi Feng, Yuntao Li, Yonggang Zhang, Sheng Qiu, Ran Chen, Yingze Ye, Lijuan Gu, Zhihong Jian, Ximing Xu, Xiaoxing Xiong
Glioma is the common, most aggressive and poorest prognostic tumor type in the brain. More and more biomarkers associated with glioma treatment, prognosis, and immunity are being discovered. Here, we aimed to explore the underlying biological functions and prognostic predictive value of Apolipoprotein L4 (APOL4) in glioma. We downloaded the expression data of APOL4 and clinical information from several
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Application of a Bayesian Network Based on Multi-Source Information Fusion in the Fault Diagnosis of a Radar ReceiverSensors (IF 3.847) Pub Date : 2022-08-25 ,DOI:10.3390/s22176396Boya Liu, Xiaowen Bi, Lijuan Gu, Jie Wei, Baozhong Liu
A radar is an important part of an air defense and combat system. It is of great significance to military defense to improve the effectiveness of radar state monitoring and the accuracy of fault diagnosis during operation. However, the complexity of radar equipment’s structure and the uncertainty of the operating environment greatly increase the difficulty of fault diagnosis in real life situations
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Numerical Study of the Effect of Thermal Stimulation on Gas Production from Marine Hydrate ReservoirsEnergy & Fuels (IF 4.654) Pub Date : 2022-08-08 ,DOI:10.1021/acs.energyfuels.2c01257Shilong Shang, Lijuan Gu, Linsen Zhan, Hailong LuThe temperature of hydrate reservoirs will decrease in a gas production process because gas hydrate dissociation is endothermic, leading to a decrease in the gas production rate as sensible heat is exhausted. Heat supply should be an effective way to alleviate the effect of temperature decrease on the production rate, by thermal stimulation, such as hot water injection into a hydrate reservoir. However ...
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Predictive value of PIMREG in the prognosis and response to immune checkpoint blockade of glioma patientsFrontiers in Immunology (IF 8.786) Pub Date : 2022-07-15 ,DOI:10.3389/fimmu.2022.946692Hua Zhu, Xinyao Hu, Shi Feng, Lijuan Gu, Zhihong Jian, Ning Zou, Xiaoxing Xiong
Glioma is the most common primary brain tumor in the human brain. The present study was designed to explore the expression of PIMREG in glioma and its relevance to the clinicopathological features and prognosis of the glioma patients. The correlations of PIMREG with the infiltrating levels of immune cells and its relevance to the response to immunotherapy were also investigated. PIMREG expression in
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NOX2-mediated reactive oxygen species are double-edged swords in focal cerebral ischemia in miceJournal of Neuroinflammation (IF 9.587) Pub Date : 2022-07-14 ,DOI:10.1186/s12974-022-02551-6Yingze, Ye, Zhihong, Jian, Tong, Jin, Yina, Li, Zhi, Zeng, Xu, Zhang, Xiaoxing, Xiong, Lijuan, Gu
Reactive oxygen species (ROS) often promote acute brain injury after stroke, but their roles in the recovery phase have not been well studied. We tested the hypothesis that ROS activity mediated by NADPH oxidase 2 (NOX2) contributes to acute brain injury but promotes functional recovery during the delayed phase, which is linked with neuroinflammation, autophagy, angiogenesis, and the PI3K/Akt signaling
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High-resolution quasi-distributed temperature and pressure sensing system for deep-sea reservoir monitoringMeasurement (IF 5.131) Pub Date : 2022-07-06 ,DOI:10.1016/j.measurement.2022.111568Xiangge He, Shangran Xie, Lijuan Gu, Fei Liu, Min Zhang, Hailong LuThe ocean contains rich oil and gas resources such as natural gas hydrate and there is an urgent need to develop tools for in-situ and continuous monitoring of the reservoir with a high resolution in the mining and development procedure. Here we report a state-of-the-art quasi-distributed temperature and pressure sensing system targeting at reservoir monitoring in deep-sea environment. The system contains ...
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An ultrasensitive fluorescent platform for monitoring GSH variation during ischemic strokeChemical Engineering Journal (IF 16.744) Pub Date : 2022-07-06 ,DOI:10.1016/j.cej.2022.137931Xiaoxing Xiong, Yingze Ye, Xiaoyang Gao, Hua Zhu, Wei Hu, Chunya Li, Zhihong Jian, Hongping Deng, Lijuan GuThe growing evidence suggests that the disturbance of redox homeostasis in the brain tissue contributes to the process of tissue damage following ischemic stroke (IS). Tracking redox process in situ is critical for diagnosis, treatment and drug design of IS. Monitoring of substances in the reduction system is more suitable than detection of molecules of oxidation system, such as reactive oxygen species ...
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Fully Optical-Driving Ionotronic InGaZnO4 Phototransistor for Gate-Tunable Bidirectional Photofiltering and Visual PerceptionIEEE Transactions on Electron Devices (IF 3.221) Pub Date : 2022-06-30 ,DOI:10.1109/ted.2022.3185954Lijuan Gu, Yanran Li, Dingdong Xie, Jie JiangRecently, fully optical-driving neuromorphic devices have attracted growing interest. However, the current device faces great challenges due to the lack of negative photoconductivity materials, which seriously hinders the further development of the visual perceptual applications using photosensitive device. Here, we propose an ionotronic neuromorphic InGaZnO4 phototransistor to establish a fully optical-driving ...
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Peripheral Organ Injury After StrokeFrontiers in Immunology (IF 8.786) Pub Date : 2022-06-01 ,DOI:10.3389/fimmu.2022.901209Jin Wang, Jiehua Zhang, Yingze Ye, Qingxue Xu, Yina Li, Shi Feng, Xiaoxing Xiong, Zhihong Jian, Lijuan Gu
Stroke is a disease with high incidence, mortality and disability rates. It is also the main cause of adult disability in developed countries. Stroke is often caused by small emboli on the inner wall of the blood vessels supplying the brain, which can lead to arterial embolism, and can also be caused by cerebrovascular or thrombotic bleeding. With the exception of recombinant tissue plasminogen activator
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JAK2/STAT3 Axis Intermediates Microglia/Macrophage Polarization During Cerebral Ischemia/Reperfusion InjuryNeuroscience (IF 3.708) Pub Date : 2022-05-20 ,DOI:10.1016/j.neuroscience.2022.05.016Yi Zhong, Lijuan Gu, Yingze Ye, Hua Zhu, Bei Pu, Jinchen Wang, Yuntao Li, Sheng Qiu, Xiaoxing Xiong, Zhihong Jian
Background: Subtypes of microglia/macrophage regulate the inflammation in the opposite direction during ischemic stroke. JAK2/STAT3 signaling pathway participates in the development of stroke-related inflammation via ischemic stimulation. However, the relationship between JAK2/STAT3 pathway and microglia/macrophage phenotype transformation is unclear. Methods: This study established a transient middle
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High Expression of CKS2 Predicts Adverse Outcomes: A Potential Therapeutic Target for GliomaFrontiers in Immunology (IF 8.786) Pub Date : 2022-05-19 ,DOI:10.3389/fimmu.2022.881453Kai Yu, Yulong Ji, Min Liu, Fugeng Shen, Xiaoxing Xiong, Lijuan Gu, Tianzhu Lu, Yingze Ye, Shi Feng, Jianying He
Cyclin-dependent kinase regulatory subunit 2 (CKS2) is a potential prognostic marker and is overexpressed in various cancers. This study analyzed sequencing and clinical data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus, with external validation using the Chinese Glioma Genome Atlas (CGGA) data. CKS2 expression in the normal brain and tumor tissue was compared. cBioPortal and MethSurv
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Metric entropy of capacity preserving dynamical systemsFuzzy Sets and Systems (IF 4.462) Pub Date : 2022-05-12 ,DOI:10.1016/j.fss.2022.04.023Lijuan Gu, Zhiming LiMetric entropy is an important isomorphic invariant in classical ergodic theory and it is one of the most accepted tools to characterize the complexity of dynamical systems. A capacity is a real-valued function but it is not additive. In contrast to the traditional measure preserving systems, the more general capacity preserving systems are investigated and an analogical metric entropy is introduced ...
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Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cerebral Ischemia/Reperfusion InjuryFrontiers in Cellular Neuroscience (IF 6.147) Pub Date : 2022-05-04 ,DOI:10.3389/fncel.2022.864426Lei Wang, Yan Liu, Xu Zhang, Yingze Ye, Xiaoxing Xiong, Shudi Zhang, Lijuan Gu, Zhihong Jian, Hongfa Wang
Ischemic stroke is an acute cerebrovascular disease characterized by sudden interruption of blood flow in a certain part of the brain, leading to serious disability and death. At present, treatment methods for ischemic stroke are limited to thrombolysis or thrombus removal, but the treatment window is very narrow. However, recovery of cerebral blood circulation further causes cerebral ischemia/reperfusion
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NLRP3 Knockout Protects against Lung Injury Induced by Cerebral Ischemia–ReperfusionOxidative Medicine and Cellular Longevity (IF 7.31) Pub Date : 2022-04-08 ,DOI:10.1155/2022/6260102Qingxue Xu, Yingze Ye, Zhuo Wang, Hua Zhu, Yina Li, Jin Wang, Wenwei Gao, Lijuan Gu
Background and Purpose. Stroke-associated pneumonia (SAP) is a common complication after stroke that increases the mortality of patients. Although there have been many studies suggesting that stroke can increase patient susceptibility to pneumonia, it is still unknown whether the treatment of stroke can also improve lung injury. We used NLRP3-knockout (NLRP3-KO) mice to verify that an improvement in
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Identifying novel therapeutic targets in gastric cancer using genome-wide CRISPR-Cas9 screeningOncogene (IF 8.756) Pub Date : 2022-02-17 ,DOI:10.1038/s41388-022-02177-1Zhi Zeng, Xu Zhang, Cong-Qing Jiang, Yong-Gang Zhang, Xue Wu, Jin Li, Shan Tang, Lang Li, Li-Juan Gu, Xiao-Yu Xie, Ying-An JiangGenome-scale CRISPR-Cas9 screening technology is a powerful tool to systematically identify genes essential for cancer cell survival. Herein, TKOv3, a genome-scale CRISPR-Cas9 knock-out library, was screened in the gastric cancer (GC) cells, and relevant validation experiments were performed. We obtained 854 essential genes for the AGS cell line, and 184 were novel essential genes. After knocking down ...
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Small-Molecule Fluorophores for Near-Infrared IIb Imaging and Image-Guided Therapy of Vascular DiseasesCCS Chemistry Pub Date : 2022-02-11 ,DOI:10.31635/ccschem.022.202101547Yang Li, Hua Zhu, Xiaobo Wang, Yan Cui, Lijuan Gu, Xiaowen Hou, Mengting Guan, Junzhu Wu, Yuling Xiao, Xiaoxing Xiong, Xianli Meng & Xuechuan Hong1Department of Neurosurgery, Renmin Hospital of Wuhan University, State Key Laboratory of Virology, Wuhan University School of Pharmaceutical Sciences, Wuhan 4300602State Key Laboratory of Southwestern Chinese Medicine Resources, Innovative Institute of Chinese
Accurate and dynamic visualization of vascular diseases can contribute to restraining further deterioration from diseases in a timely manner. However, visualization is still unable to precisely determine whether and to what extent blood vessels or brain tissues are damaged. Here, we report novel benzo-bis(1,2,5-thiadiazole)-based second near-infrared region (NIR-II) fluorophores HY1–HY4 with highly
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Estimating the Pinning Force of Surface Nanobubbles Based on Trapped Nanobubble ProtrudingThe Journal of Physical Chemistry C (IF 4.177) Pub Date : 2022-02-08 ,DOI:10.1021/acs.jpcc.1c10103Dayong Li, Juan GuSurface nanobubbles as the main gaseous domains at the solid–liquid interface have attracted extensive interest because of their potential applications. Some remarkable properties of surface nanobubbles such as small contact angle and long lifetime are related to the force that pins them onto their substrates. However, the pinning force of nanosized surface bubbles is yet to be quantified experimentally ...
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The Hypoxia-Related Gene COL5A1 Is a Prognostic and Immunological Biomarker for Multiple Human TumorsOxidative Medicine and Cellular Longevity (IF 7.31) Pub Date : 2022-01-17 ,DOI:10.1155/2022/6419695Hua Zhu, Xinyao Hu, Shi Feng, Zhihong Jian, Ximing Xu, Lijuan Gu, Xiaoxing Xiong
Background. Collagen type V alpha 1 chain (COL5A1) is a hypoxia-related gene (a collagen family protein) and participates in the formation of the extracellular matrix. Although some evidence supports a significant role for COL5A1 in the progression of several cancers, a pan-cancer analysis of COL5A1 is not currently available. Herein, we aimed to assess the prognostic value of COL5A1 in 33 human cancers
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A Second Near-Infrared Ru(II) Polypyridyl Complex for Synergistic Chemo-Photothermal TherapyJournal of Medicinal Chemistry (IF 8.039) Pub Date : 2022-01-07 ,DOI:10.1021/acs.jmedchem.1c01736Yishen Liu, Qianqian Li, Meijia Gu, Disheng Lu, Xiaoxing Xiong, Zhiyun Zhang, Yanna Pan, Yuqin Liao, Qihang Ding, Wanxia Gong, Dean Shuailin Chen, Mengting Guan, Junzhu Wu, Zhiquan Tian, Hai Deng, Lijuan Gu, Xuechuan Hong, Yuling XiaoThe clinical success of cisplatin ushered in a new era of the application of metallodrugs. When it comes to practice, however, drug resistance, tumor recurrence, and drug systemic toxicity make it implausible to completely heal the patients. Herein, we successfully transform an electron acceptor [1, 2, 5]thiadiazolo[3,4-g]quinoxaline into a novel second near-infrared (NIR-II) fluorophore H7. After ...
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Downregulation of CYP39A1 Serves as a Novel Biomarker in Hepatocellular Carcinoma with Worse Clinical OutcomeOxidative Medicine and Cellular Longevity (IF 7.31) Pub Date : 2021-12-31 ,DOI:10.1155/2021/5175581Dan Li, Tao Yu, Junjie Hu, Jie Wu, Shi Feng, Qingxue Xu, Hua Zhu, Xu Zhang, Yonggang Zhang, BenHong Zhou, Lijuan Gu, Zhi Zeng
Background. CYP39A1 is a poorly characterized metabolic enzyme that has been investigated in a few tumors. However, the role of CYP39A1 in hepatocellular carcinoma (HCC) has not yet been clarified. In this study, the expression and clinical significance of CYP39A1 in HCC were explored. Methods. CYP39A1 protein expression was detected in Akt/c-Met-induced HCC mice and 14 paired fresh HCC samples as
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Preliminary evaluation of the economic potential of the technologies for gas hydrate exploitationEnergy (IF 8.857) Pub Date : 2021-12-24 ,DOI:10.1016/j.energy.2021.123007Xuejun Chen, Hailong Lu, Lijuan Gu, Shilong Shang, Yi Zhang, Xin Huang, Le ZhangSeveral trial productions of natural gas hydrate (NGH) on onshore and offshore reservoirs have been implemented, signaling the start of the stage of technology development for its industrial exploitation. Several methods for NGH exploitation have been proposed, but none of them has been verified applicable to the commercial exploitation of NGH. The applicability of a technology to NGH exploitation ...
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Analysis and Suppression of Aliased Noises in Time-Division-Multiplexing Interferometric Fiber-Optic Sensor ArrayJournal of Lightwave Technology (IF 4.439) Pub Date : 2021-12-22 ,DOI:10.1109/jlt.2021.3137319Fei Liu, Shangran Xie, Min Zhang, Xiangge He, Duo Yi, Lijuan Gu, Yi Zhang, Xian Zhou, Keping LongAliased noises elevate the ultimate noise level of a pulse-triggered time-division-multiplexing (TDM) interferometric fiber-optic sensor array. Here we for the first time present an analytical model of the aliasing factor based on noise power spectral density analysis of the interferometric fiber sensor array. In contrast to the previous reports, the aliasing factor is found not only dependent on the ...
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