- 作 者: "feng he"
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[Application of vestibular function examination in the analysis of damaged site in patients with acute vestibular neuritis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery Pub Date : 2023-04-01 ,DOI:10.13201/j.issn.2096-7993.2023.04.005Feng He,Junliang Han,Ya Bai,Yuanyuan Wang,Dong Wei,Ying Shi,Xingyue An,Wei FuObjective:To analyze the site of vestibular nerve damaged in patients with acute vestibular neuritis. Methods:Fifty-seven patients with acute vestibular neuritis were recruited, and each patient underwent caloric irrigation test, video head impulse test（vHIT） and vestibular evoked myogenic potentials（VEMPs）. The results were further analyzed. Results:Analysis of abnormal rates of different vestibular ...
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The chromosome-level genome of Eucommia ulmoides provides insights into sex differentiation and α-linolenic acid biosynthesisFrontiers in Plant Science (IF 6.627) Pub Date : 2023-03-31 ,DOI:10.3389/fpls.2023.1118363Qingxin Du, Zixian Wu, Panfeng Liu, Jun Qing, Feng He, Lanying Du, Zhiqiang Sun, Lili Zhu, Hongchu Zheng, Zongyi Sun, Long Yang, Lu Wang, Hongyan Du
Eucommia ulmoides Oliver is a typical dioecious plant endemic to China that has great medicinal and economic value. Here, we report a high-quality chromosome-level female genome of E. ulmoides obtained by PacBio and Hi-C technologies. The size of the female genome assembly was 1.01 Gb with 17 pseudochromosomes and 31,665 protein coding genes. In addition, Hi-C technology was used to reassemble the
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Machine learning vs deep learning in stock market investment: an international evidenceAnnals of Operations Research (IF 4.82) Pub Date : 2023-03-30 ,DOI:10.1007/s10479-023-05286-6Jing Hao, Feng He, Feng Ma, Shibo Zhang, Xiaotao ZhangMachine learning and deep learning are powerful tools for quantitative investment. To examine the effectiveness of the models in different markets, this paper applies random forest and DNN models to forecast stock prices and construct statistical arbitrage strategies in five stock markets, including mainland China, the United States, the United Kingdom, Canada and Japan. Each model is applied to the ...
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New eudesmanolides from Artemisia verlotorum and their potential targets of hepatocellular carcinoma by network pharmacologyFitoterapia (IF 3.204) Pub Date : 2023-03-29 ,DOI:10.1016/j.fitote.2023.105491Wei Dong, Ke-Xin Yang, Xiao-Feng He, Tian-Ze Li, Ji-Jun ChenFractionation of the ethanol extract of Artemisia verlotorum led to the identification of eight undescribed eudesmane-type sesquiterpenoids, artemverlolides A-H (1–8). Their structures were determined by spectral analyses (HRESIMS, 1D and 2D NMR, IR, and ECD). Network pharmacology predicted that compounds 1–8 might be target on AURKA, CCNA2, CYP2C19, and EPHX2 with possibly antihepatoma effect from ...
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ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosisJournal of Hepatology (IF 30.083) Pub Date : 2023-03-28 ,DOI:10.1016/j.jhep.2023.03.016Feng He, Peng Zhang, Junlai Liu, Ruolei Wang, Randal J Kaufman, Benjamin C Yaden, Michael KarinBackground & Aims Hepatocellular carcinoma (HCC), a leading cause of cancer death, is associated with viral hepatitis, non-alcoholic and alcoholic steatohepatitis (NASH, ASH), all of which trigger endoplasmic reticulum (ER) stress, hepatocyte death, inflammation, and compensatory proliferation. Using ER stress-prone MUP-uPA mice, we established that ER stress and hypernutrition cooperate to cause NASH ...
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Achieving High Performance Organic Solar Cells with a Closer π-π Distance in Branched Alkyl-chain AcceptorsJournal of Materials Chemistry A (IF 14.511) Pub Date : 2023-03-28 ,DOI:10.1039/d3ta01049jPu Tan, Congcong Cao, Yue Cheng, Hui Chen, Hanjian Lai, Yulin Zhu, Liang Han, Jianfei Qu, Nan Zheng, Yuan-Zhu Zhang, Feng HeSide-chain functional groups have been shown not only ensure solubility but also influence molecular packing behavior, and side-chain modification is an important strategy in the optimization of photovoltaic performance. Instead of focusing on the size of the alkyl side chains, we have investigated the influence of side-chain configurations on the properties of acceptors and organic solar cells (OSC) ...
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Generation of a humanized afucosylated BAFF-R antibody with broad activity against human B-cell malignancies.Blood Advances Pub Date : 2023-03-28 ,DOI:10.1182/bloodadvances.2022008560Dong,Joo Y Song,Elana Thieme,Aaron Anderson,Elizabeth Oh,Wesley A Cheng,Benjamin Z Kuang,Vincent Lee,Tiantian Zhang,Zhe Wang,Szymon Szymura,D Lynne Smith,Jianbing Zhang,Weihong Nian,Xintong Zheng,Feng He,Qing Zhou,Soung-Chul Cha,Alexey V Danilov,Hong Qin,Larry W Kwak
B-cell activating factor receptor (BAFF-R) is a mature B-cell survival receptor, which is highly expressed in a wide variety of B-cell malignancies but with minimal expression in immature B cells. These properties make BAFF-R an attractive target for therapy of B-cell lymphomas. We generated a novel humanized anti BAFF-R monoclonal antibody (mAb) with high specificity and potent in vitro and in vivo
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One-Pot Rapid Synthesis of Cu2+-Doped GOD@MOF to Amplify the Antitumor Efficacy of Chemodynamic TherapyACS Applied Materials & Interfaces (IF 10.383) Pub Date : 2023-03-27 ,DOI:10.1021/acsami.3c00562Qing Li, Jiantao Yu, Li Lin, Yulin Zhu, Zixiang Wei, Feiyan Wan, Xindan Zhang, Feng He, Leilei TianChemodynamic therapy (CDT) relies on the transformation of intracellular hydrogen peroxide (H2O2) to hydroxyl radicals (·OH) with higher toxicity under the catalysis of Fenton/Fenton-like reagents, which amplifies the oxidative stress and induces significant cellular apoptosis. However, the CDT efficacy is generally limited by the overexpressed GSH and insufficient endogenous H2O2 in tumors. Co-delivery ...
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Oxygen-assisted spinodal structure achieves 1.5 GPa yield strength in a ductile refractory high-entropy alloyJournal of Materials Science & Technology (IF 10.319) Pub Date : 2023-03-24 ,DOI:10.1016/j.jmst.2023.01.038Dingcong Cui, Yuyu Zhang, Linxiang Liu, Yue Li, Lei Wang, Zhijun Wang, Junjie Li, Jincheng Wang, Feng HeRefractory high-entropy alloys (RHEAs) with room-temperature ductility are drawing growing attention for potential high-temperature applications. However, the most widely used metallurgical mechanisms appear weak in optimizing their strength and ductility. Here, we report that the nanoscale spinodal structure in Ti41V27Hf15Nb15O2 leads to the highest tensile yield strength (∼1.5 GPa) among the existing ...
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Adenosine 2 receptor regulates autophagy and apoptosis to alleviate ischemia reperfusion injury in type 2 diabetes via IRE-1 signalingBMC Cardiovascular Disorders (IF 2.174) Pub Date : 2023-03-24 ,DOI:10.1186/s12872-023-03116-yMohamed Bassirou Yacouba Moukeila, Erick Thokerunga, Feng He, Christian Cedric Bongolo, Yun Xia, Fuyu Wang, Adamou Foumakoye Gado, Hama Mamoudou, Shahzad Khan, Bonkano Ousseina, Hadjara Abdoulkarim Ousmane, Drissa Diarra, Jianjuan Ke, Zongze Zhang, Yanlin Wang
This study aimed to determine the effect and mechanism of action of adenosine 2 receptor (A2R) activation on myocardial ischemia reperfusion injury (MIRI) under diabetic conditions. MIRI type 2 diabetic rats and H9C2 cardiomyocytes were treated with A2R agonist and then subjected to hypoxia for 6 h and reoxygenation for 18 h. Myocardial damage, and infarct size were determined by cardiac ultrasound
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Wave-Packet Surface Propagation for Light-Induced Molecular DissociationarXiv - PHYS - Optics Pub Date : 2023-03-24 ,DOI:arxiv-2303.13991Shengzhe Pan, Zhaohan Zhang, Chenxi Hu, Peifen Lu, Xiaochun Gong, Ruolin Gong, Wenbin Zhang, Lianrong Zhou, Chenxu Lu, Menghang Shi, Zhejun Jiang, Hongcheng Ni, Feng He, Jian WuRecent advances in laser technology have enabled tremendous progress in photochemistry, at the heart of which is the breaking and formation of chemical bonds. Such progress has been greatly facilitated by the development of accurate quantum-mechanical simulation method, which, however, does not necessarily accompany clear dynamical scenarios and is rather often a black box, other than being computationally ...
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Wave-Packet Surface Propagation for Light-Induced Molecular DissociationarXiv - PHYS - Chemical Physics Pub Date : 2023-03-24 ,DOI:arxiv-2303.13991Shengzhe Pan, Zhaohan Zhang, Chenxi Hu, Peifen Lu, Xiaochun Gong, Ruolin Gong, Wenbin Zhang, Lianrong Zhou, Chenxu Lu, Menghang Shi, Zhejun Jiang, Hongcheng Ni, Feng He, Jian WuRecent advances in laser technology have enabled tremendous progress in photochemistry, at the heart of which is the breaking and formation of chemical bonds. Such progress has been greatly facilitated by the development of accurate quantum-mechanical simulation method, which, however, does not necessarily accompany clear dynamical scenarios and is rather often a black box, other than being computationally ...
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Sedimentary characteristics and depositional evolution of carbonate platform during the Cambrian and Ordovician in eastern Tarim Basin, NW ChinaFrontiers of Earth Science (IF 2.273) Pub Date : 2023-03-23 ,DOI:10.1007/s11707-022-1028-8Jingyan Liu, Shiqiang Xia, Junlong Zhang, Feng He, Yuhan Cheng, Yi Zhu, Zhaoqin Chen, Huoxiang DongThe eastern Tarim Basin (Tadong Area) has gained wide attentions on large-scale marine carbonate reservoirs in Cambrian-Ordovician due to significant hydrocarbon discoveries. A systematic analysis combining thin sections, cores, wireline logs, and seismic data is conducted on Cambrian-Ordovician carbonate platform in the whole eastern Tarim Basin, including Gucheng area, Majiaer area, and western Luobopo ...
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Clinical and Economic Evaluation of Ultrasound-Guided Radiofrequency Ablation vs. Parathyroidectomy for Patients with Primary Hyperparathyroidism: A Cohort StudyAcademic Radiology (IF 5.482) Pub Date : 2023-03-23 ,DOI:10.1016/j.acra.2023.02.020Hui-hui Chai, Zhan-jing Dai, Bai Xu, Qiao-hong Hu, Hong-feng He, Ying Xin, Wen-wen Yue, Cheng-zhong PengRationale and Objectives To compare the clinical and economic effects of ultrasound (US)-guided radiofrequency ablation (RFA) with parathyroidectomy (PTX) for primary hyperparathyroidism (PHPT). Materials and Methods From April 2014 to April 2021, 123 PHPT patients who received US-guided RFA or PTX were studied. Propensity score (PS) matching was used to balance the baseline data of the two groups ...
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Time-resolved cryo-EM of G protein activation by a GPCRbioRxiv - Pharmacology and Toxicology Pub Date : 2023-03-21 ,DOI:10.1101/2023.03.20.533387Makaía M. Papasergi-Scott, Guillermo Pérez-Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B. Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K. Kobilka, Peter W. Hildebrand, Georgios Skiniotis
G protein-coupled receptors (GPCRs) activate heterotrimeric G proteins by stimulating the exchange of guanine nucleotide in the G alpha subunit. To visualize this mechanism, we developed a time-resolved cryo-EM approach that examines the progression of ensembles of pre-steady-state intermediates of a GPCR-G protein complex. Using variability analysis to monitor the transitions of the stimulatory Gs
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Time-resolved cryo-EM of G protein activation by a GPCRbioRxiv - Physiology Pub Date : 2023-03-21 ,DOI:10.1101/2023.03.20.533387Makaía M. Papasergi-Scott, Guillermo Pérez-Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B. Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K. Kobilka, Peter W. Hildebrand, Georgios Skiniotis
G protein-coupled receptors (GPCRs) activate heterotrimeric G proteins by stimulating the exchange of guanine nucleotide in the G alpha subunit. To visualize this mechanism, we developed a time-resolved cryo-EM approach that examines the progression of ensembles of pre-steady-state intermediates of a GPCR-G protein complex. Using variability analysis to monitor the transitions of the stimulatory Gs
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Identifying ITGB2 as a Potential Prognostic Biomarker in Ovarian CancerDiagnostics (IF 3.992) Pub Date : 2023-03-18 ,DOI:10.3390/diagnostics13061169Chanyuan Li, Ting Deng, Junya Cao, Yun Zhou, Xiaolin Luo, Yanling Feng, He Huang, Jihong Liu
Epithelial ovarian cancer is by far the most lethal gynecological malignancy. The exploration of promising immunomarkers to predict prognosis in ovarian cancer patients remains challenging. In our research, we carried out an integrated bioinformatic analysis of genome expressions and their immune characteristics in the ovarian cancer microenvironment with validation in different experiments. We filtrated
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Toripalimab combined with lenvatinib and GEMOX is a promising regimen as first-line treatment for advanced intrahepatic cholangiocarcinoma: a single-center, single-arm, phase 2 studySignal Transduction and Targeted Therapy (IF 38.104) Pub Date : 2023-03-17 ,DOI:10.1038/s41392-023-01317-7Dong Wu, Hui-Chuan Sun, Fei Liang, Yuan Ji, Yi Chen, Guo-Huan Yang, Jia-Cheng Lu, Xian-Long Meng, Xin-Ying Wang, Lei Sun, Ning-Ling Ge, Xiao-Wu Huang, Shuang-Jian Qiu, Xin-Rong Yang, Qiang Gao, Yi-Feng He, Yang Xu, Jian Sun, Zheng-Gang Ren, Jia Fan, Jian ZhouAdvanced intrahepatic cholangiocarcinoma (ICC) has a dismal prognosis. Here, we report the efficacy and safety of combining toripalimab, lenvatinib, and gemcitabine plus oxaliplatin (GEMOX) as first-line therapy for advanced ICC. Thirty patients with pathologically confirmed advanced ICC received intravenous gemcitabine (1 g/m2) on Days 1 and 8 and oxaliplatin (85 mg/m2) Q3W for six cycles along with ...
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Multiphoton Ionization Reduction of Atoms in Two-Color Femtosecond Laser FieldsPhysical Review Letters (IF 9.185) Pub Date : 2023-03-14 ,DOI:10.1103/physrevlett.130.113201Hong-Bin Yao, Qi-Wen Qu, Zhao-Han Zhang, Jia-Wei Wang, Jian Gao, Chen-Xi Hu, Hui Li, Jian Wu, Feng HeWe report the ionization reduction of atoms in two-color femtosecond laser fields in this joint theoretical-experimental study. For the multiphoton ionization of atoms using a 400 nm laser pulse, the ionization probability is reduced if another relatively weak 800 nm laser pulse is overlapped. Such ionization reduction consistently occurs regardless of the relative phase between the two pulses. The ...
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Mendelian randomization analysis suggests no associations of herpes simplex virus infections with systemic lupus erythematosusJournal of Medical Virology (IF 20.693) Pub Date : 2023-03-10 ,DOI:10.1002/jmv.28649Min-Jing Chang, Meng-Ting Liu, Miao-Ran Chen, Nan Li, Yu-Hui Zhao, Sheng-Xiao Zhang, Pei-Feng He, Qi YuSystemic lupus erythematosus (SLE) characterized by immune dysfunction is possibly more vulnerable to herpes simplex virus (HSV) infection. The infection has been intensively considered a common onset and exacerbation of SLE. This study is aimed at elucidating the causal association between SLE and HSV. A bidirectional two-sample Mendelian Randomization (TSMR) analysis was systematically conducted ...
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Improving Video Retrieval by Adaptive MarginarXiv - CS - Computer Vision and Pattern Recognition Pub Date : 2023-03-09 ,DOI:arxiv-2303.05093Feng He, Qi Wang, Zhifan Feng, Wenbin Jiang, Yajuan Lv, Yong zhu, Xiao TanVideo retrieval is becoming increasingly important owing to the rapid emergence of videos on the Internet. The dominant paradigm for video retrieval learns video-text representations by pushing the distance between the similarity of positive pairs and that of negative pairs apart from a fixed margin. However, negative pairs used for training are sampled randomly, which indicates that the semantics ...
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Improving Video Retrieval by Adaptive MarginarXiv - CS - Computation and Language Pub Date : 2023-03-09 ,DOI:arxiv-2303.05093Feng He, Qi Wang, Zhifan Feng, Wenbin Jiang, Yajuan Lv, Yong zhu, Xiao TanVideo retrieval is becoming increasingly important owing to the rapid emergence of videos on the Internet. The dominant paradigm for video retrieval learns video-text representations by pushing the distance between the similarity of positive pairs and that of negative pairs apart from a fixed margin. However, negative pairs used for training are sampled randomly, which indicates that the semantics ...
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Glucometer-based biosensor for the determination of ractopamine in animal-derived foods using rolling circle amplificationMicrochimica Acta (IF 6.408) Pub Date : 2023-03-08 ,DOI:10.1007/s00604-023-05715-0Feng He, Tengfei Li, Haijie Wang, Pengfei Du, Weiting Wang, Tianyu Tan, Yaobo Liu, Shoujing Wang, Yanli Ma, Yuanshang Wang, Peng Hu, A. M. Abd El-AtyScreening for persistent organic pollutants (POPs) in food is a complex and challenging process, as POPs can be present in very low levels and can be difficult to detect. Herein, we developed an ultrasensitive biosensor based on a rolling circle amplification (RCA) platform using a glucometer to determine POP. The biosensor was constructed using gold nanoparticle probes modified with antibodies and ...
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Orthodontic-surgical treatment for severe skeletal class II malocclusion with vertical maxillary excess and four premolars extraction: A case report.World Journal of Clinical Cases (IF 1.534) Pub Date : 2023-3-7 ,DOI:10.12998/wjcc.v11.i5.1106Yi-Wen Zhou, Yan-Yi Wang, Zhi-Feng He, Ming-Xing Lu, Gui-Feng Li, Huang Li
Patient satisfaction with facial appearance at the end of orthodontic camouflage treatment is very important, especially for skeletal malocclusion. This case report highlights the importance of the treatment plan for a patient initially treated with four-premolar-extraction camouflage, despite indications for orthognathic surgery.
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Associations of polygenic risk scores with posttraumatic stress symptom trajectories following combat deploymentPsychological Medicine (IF 10.592) Pub Date : 2023-03-06 ,DOI:10.1017/s0033291723000211Laura Campbell-Sills, Santiago Papini, Sonya B. Norman, Karmel W. Choi, Feng He, Xiaoying Sun, Ronald C. Kessler, Robert J. Ursano, Sonia Jain, Murray B. Stein
Background Identification of genetic risk factors may inform the prevention and treatment of posttraumatic stress disorder (PTSD). This study evaluates the associations of polygenic risk scores (PRS) with patterns of posttraumatic stress symptoms following combat deployment. Method US Army soldiers of European ancestry (n = 4900) provided genomic data and ratings of posttraumatic stress symptoms before
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Active compounds and potential targets of Shuganning injection in the treatment of hepatocellular carcinoma by network pharmacology and in vitro validationNaunyn-Schmiedeberg's Archives of Pharmacology (IF 3.195) Pub Date : 2023-03-04 ,DOI:10.1007/s00210-023-02432-6Xiao Han, Jiayan Huang, Jia Lu, Feng He, Fang Wang, Shuangfeng Li, Hao Zhong, Haiyang Yu, Weiling Pu
Shuganning injection (SGNI), a TCM (traditional Chinese medicine) injection with good hepatoprotective effects, exerted therapeutic effects on hepatocellular carcinoma (HCC). However, the active compounds and effects of SGNI on HCC remain unclear. The objective of this study was to investigate the active compounds and potential targets of SGNI in the treatment of HCC, and explore the molecular mechanisms
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Dynamic Deformation Behaviors of the Levitation Electromagnets of High-Speed Maglev Vehicle Negotiating a Sharp Horizontal Curve.Sensors (IF 3.847) Pub Date : 2023-03-03 ,DOI:10.3390/s23052785Qingsong Yu,Xiaoqing Li,Qing Shao,Tian Han,Chunfa Zhao,Feng He
The elastic deformation of the levitation electromagnet (LM) of the high-speed maglev vehicle brings uneven levitation gaps and displacement differences between measured gap signals and the real gap in the middle of the LM, and then reduces dynamic performances of the electromagnetic levitation unit. However, most of the published literature has paid little attention to the dynamic deformation of the
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Thermoelectric properties of ductile Ag2S0.7Te0.3 prepared via zone melting methodSolid State Communications (IF 1.934) Pub Date : 2023-03-02 ,DOI:10.1016/j.ssc.2023.115123Min Jin, Xinyu Lu, Linlin Guo, Xinyu Lu, Feng He, Xudong Bai, Rongbin Li, Siqi LinRecently, the discovery of ductility inorganic semiconductors Ag2S-based alloys have drawn significant interest in hetero-shaped thermoelectric applications. In this work, Ag2S0.7Te0.3 inorganic thermoelectric compound was prepared using the zone melting technique. The crystal structure of Ag2S0.7Te0.3 is similar to that of the cubic-structured Ag2S compound, in which S and Te atoms are randomly occupied ...
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Coarse-grained model of whole blood hemolysis and morphological analysis of erythrocyte population under non-physiological shear stress flow environmentPhysics of Fluids (IF 4.98) Pub Date : 2023-03-01 ,DOI:10.1063/5.0137517Zhike Xu, Chenyang Wang, Feng He, Pengfei Hao, Xiwen ZhangErythrocyte dynamics and hemorheology exist inextricably connection. In order to further explore the population dynamics of erythrocytes in non-physiological shear stress flow and its microscopic hemolysis mechanism, this study improved the coarse-grained erythrocytes damaged model and established the hemoglobin (Hb) diffusion model based on the transport dissipative particle dynamics. The whole blood ...
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Graphene-based magnetic composite foam with hierarchically porous structure for efficient microwave absorptionCarbon (IF 11.307) Pub Date : 2023-03-01 ,DOI:10.1016/j.carbon.2023.02.066Shuangshuang Li, Tiantian Ma, Zheyuan Chai, Zihang Zhang, Mingyang Zhu, Xinwei Tang, Xu Zhao, Yezi Lu, Qianqian Lan, Zhenyu Wang, Feng He, Zicheng Wang, Tianxi LiuIn the design of microwave absorbing materials, synergistically optimizing the relationship between impedance matching and attenuation constant remains a great challenge. In this work, a hierarchically porous graphene/iron trioxide magnetic composite foam (GMF) is successfully constructed by an electrostatic assembly of metal-organic frameworks (MOF) in reduced graphene oxide skeletons and subsequent ...
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