- 作 者: "chang su"
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Efficient secretory expression of phospholipase D for the high-yield production of phosphatidylserine and phospholipid derivates from soybean lecithinSynthetic and Systems Biotechnology Pub Date : 2023-03-23 ,DOI:10.1016/j.synbio.2023.03.006Peng Zhang, Jin-Song Gong, Zhi-Hao Xie, Chang Su, Xiao-Mei Zhang, Zhi-Ming Rao, Zheng-Hong Xu, Jin-Song ShiPhospholipase D (PLD) is an essential biocatalyst for the biological production of phosphatidylserine and phospholipid modification. However, the efficient heterologous expression of PLD is limited by its cell toxicity. In this study, a PLD was secretory expressed efficiently in Bacillus subtilis with an activity around 100 U/mL. A secretory expression system containing the signal peptide SPEstA and ...
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Seismic degradation behavior of steel-FRP composite bar reinforced concrete beams in marine environment based on experimental and numerical investigationComposite Structures (IF 6.603) Pub Date : 2023-03-21 ,DOI:10.1016/j.compstruct.2023.116949Chang Su, Xin Wang, Lining Ding, Zhishen WuThis study investigated the seismic behavior of seawater sea sand concrete (SWSSC, which is made of seawater, sea sand, ordinary aggregate and cement) beams reinforced with steel bars in a marine environment. To improve the durability of the specimens, different types of reinforcements, namely fiber reinforced polymer (FRP), steel-FRP composite bars (SFCBs), and macro basalt fibers, were introduced ...
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Title: Biomedical Discovery through the integrative Biomedical Knowledge Hub (iBKH)iScience (IF 6.107) Pub Date : 2023-03-21 ,DOI:10.1016/j.isci.2023.106460Chang Su, Yu Hou, Manqi Zhou, Suraj Rajendran, Jacqueline R.M.A. Maasch, Zehra Abedi, Haotan Zhang, Zilong Bai, Anthony Cuturrufo, Winston Guo, Fayzan F. Chaudhry, Gregory Ghahramani, Jian Tang, Feixiong Cheng, Yue Li, Rui Zhang, Steven T DeKosky, Jiang Bian, Fei WangThe abundance of biomedical knowledge gained from biological experiments and clinical practices is an invaluable resource for biomedicine. The emerging biomedical knowledge graphs (BKGs) provide an efficient and effective way to manage the abundant knowledge in biomedical and life science. In this study, we created a comprehensive BKG called the integrative Biomedical Knowledge Hub (iBKH) by harmonizing ...
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Versatile Depth Estimator Based on Common Relative Depth Estimation and Camera-Specific Relative-to-Metric Depth ConversionarXiv - CS - Computer Vision and Pattern Recognition Pub Date : 2023-03-20 ,DOI:arxiv-2303.10991Jinyoung Jun, Jae-Han Lee, Chang-Su KimA typical monocular depth estimator is trained for a single camera, so its performance drops severely on images taken with different cameras. To address this issue, we propose a versatile depth estimator (VDE), composed of a common relative depth estimator (CRDE) and multiple relative-to-metric converters (R2MCs). The CRDE extracts relative depth information, and each R2MC converts the relative information ...
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High-level expression and characterization of a highly active hyaluronate lyase HylC with significant potential in hyaluronan oligosaccharide preparationJournal of Biotechnology (IF 3.595) Pub Date : 2023-03-15 ,DOI:10.1016/j.jbiotec.2023.03.003Yue-Sheng Zhang, Jia-Yu Jiang, Jin-Song Gong, Chang Su, Heng Li, Chuan-Li Kang, Lei Liu, Zheng-Hong Xu, Jin-Song ShiHyaluronate lyases (HA lyases) have been proved to distribute widely among microorganisms, with large potential in hyaluronan processing. Here, a highly active HA lyase HylC from Citrobacter freundii strain Cf1 is reported. HylC was expressed in Escherichia coli BL21(DE3) under the regulation of T7 promoter, and purified to electrophoretic homogeneity for enzymatic characterization, which suggested ...
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Genetic variation reveals the enhanced microbial hyaluronan biosynthesis via atmospheric and room temperature plasmaCarbohydrate Polymers (IF 10.723) Pub Date : 2023-03-14 ,DOI:10.1016/j.carbpol.2023.120809Zhi-Yuan Yao, Jin-Song Gong, Yu-Ru Liu, Jia-Yu Jiang, Yue-Sheng Zhang, Chang Su, Heng Li, Chuan-Li Kang, Lei Liu, Zheng-Hong Xu, Jin-Song ShiThis study reveals the genetic and biochemical changes underlying the enhanced hyaluronan (HA) biosynthesis in Streptococcus zooepidemicus. After multiple rounds of atmospheric and room temperature plasma (ARTP) mutagenesis combined with novel bovine serum albumin/cetyltrimethylammonium bromide coupled high-throughput screening assay, the HA yield of the mutant was increased by 42.9% and reached 0 ...
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High-level expression and characterization of a highly active hyaluronate lyase HylC with significant potential in hyaluronan oligosaccharide preparation.Journal of biotechnology Pub Date : 2023-03-14 ,DOI:10.1016/j.jbiotec.2023.03.003Yue-Sheng Zhang,Jia-Yu Jiang,Jin-Song Gong,Chang Su,Heng Li,Chuan-Li Kang,Lei Liu,Zheng-Hong Xu,Jin-Song ShiHyaluronate lyases (HA lyases) have been proved to distribute widely among microorganisms, with large potential in hyaluronan processing. Here, a highly active HA lyase HylC from Citrobacter freundii strain Cf1 is reported. HylC was expressed in Escherichia coli BL21(DE3) under the regulation of T7 promoter, and purified to electrophoretic homogeneity for enzymatic characterization, which suggested ...
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Context-Based Trit-Plane Coding for Progressive Image CompressionarXiv - EE - Image and Video Processing Pub Date : 2023-03-10 ,DOI:arxiv-2303.05715Seungmin Jeon, Kwang Pyo Choi, Youngo Park, Chang-Su KimTrit-plane coding enables deep progressive image compression, but it cannot use autoregressive context models. In this paper, we propose the context-based trit-plane coding (CTC) algorithm to achieve progressive compression more compactly. First, we develop the context-based rate reduction module to estimate trit probabilities of latent elements accurately and thus encode the trit-planes compactly ...
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Video Frame Interpolation Based on Symmetric and Asymmetric MotionsIEEE Access (IF 3.476) Pub Date : 2023-03-06 ,DOI:10.1109/access.2023.3252911Whan Choi, Yeong Jun Koh, Chang-Su Kim
Video frame interpolation is the task to synthesize intermediate frames between consecutive frames to increase the frame rate. Recently, various deep-learning techniques have been proposed to interpolate intermediate frames more reliably. However, many existing methods use either symmetric (linear) or asymmetric (non-linear) schemes only to estimate motions for the warping process, resulting in unreliable
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Association of burnout with depression in pharmacists: A network analysisFrontiers in Psychiatry (IF 5.435) Pub Date : 2023-03-06 ,DOI:10.3389/fpsyt.2023.1145606Mu He, Kuiliang Li, Xuejiao Tan, Lei Zhang, Chang Su, Keyong Luo, Xi Luo, Chang Liu, Mengxue Zhao, Xiaoqing Zhan, Qian Wang, Jing Cen, Jun Lv, Bangbi Weng, Zhengzhi Feng, Lei Ren, Guoyu Yang, Feifei WangBackground Burnout and depression have overlapping symptoms, but the extent of overlap remains unclear, and the complex relationship between burnout and depression in pharmacists is rarely explored. Methods We investigated burnout and depression in 1,322 frontline pharmacists, and explored the complex relationship between burnout and depression in those pharmacists using network analysis. Results Network ...
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Classifying habitat characteristics of wetlands using a self-organizing mapEcological Informatics (IF 4.498) Pub Date : 2023-03-04 ,DOI:10.1016/j.ecoinf.2023.102048Seong-Hyeon Kim, Kwang-Jin Cho, Tae-Su Kim, Chang-Su Lee, Thakur Dhakal, Gab-Sue JangWetlands are nutrient-rich and biodiverse ecosystems that provide habitats for various animals and plants and protect against flooding. Classification of wetlands provides information to conservation planners and resource managers for ecosystem service determination. Many ecological case studies illuminate the self-organizing map (SOM) as a robust and powerful data classification and visualization ...
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Performance optimization of photovoltaic and solar cells via a hybrid and efficient chimp algorithmSolar Energy (IF 7.188) Pub Date : 2023-03-03 ,DOI:10.1016/j.solener.2023.02.036Chao Yang, Chang Su, Haiting Hu, Mostafa Habibi, Hamed Safarpour, Mohamed Amine KhadimallahThe global shift toward solar energy has resulted in the advancement of research into the manufacture of high-performance solar cells. It is critical to accurately model and identify the parameters of solar cells. Numerous models of solar cells have been presented thus far, including the single-diode, the double-diode, and the three-diode models. Every model contains a number of unidentified parameters ...
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Enhancing mechanical properties via the dual effect of Ni addition and temperature gradient for 5 μm Cu/Sn-3.0Ag-0.5Cu/Cu transient liquid phase bondingMaterials Science and Engineering: A (IF 6.044) Pub Date : 2023-03-01 ,DOI:10.1016/j.msea.2023.144863Chen-Sung Chao, Zih-You Wu, Yin-Ku Lee, Pin-Wei Huang, Shou-Yi Chang, Su-Yueh Tsai, Jenq-Gong DuhMore recently, transient liquid phase bonding was widely considered to be a potential bonding method in 3D-IC technology as the full intermetallic compounds (IMCs) joints were characterized by superior bonding strength and reliable high temperature service. Nevertheless, preferred grain orientation and coarsening grains have been the shortcoming for traditional Cu/Sn/Cu transient liquid-phase bumps ...
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Mesenchymal Stem-Like Cells Derived from the Ventricle More Effectively Enhance Invasiveness of Glioblastoma Than Those Derived from the Tumor.Yonsei Medical Journal Pub Date : 2023-03-01 ,DOI:10.3349/ymj.2022.0430Junseong Park,Dongkyu Lee,Jin-Kyoung Shim,Seon-Jin Yoon,Ju Hyung Moon,Eui Hyun Kim,Jong Hee Chang,Su-Jae Lee,Seok-Gu Kang
PURPOSE Glioblastoma (GBM) is one of the most lethal human tumors with a highly infiltrative phenotype. Our previous studies showed that GBM originates in the subventricular zone, and that tumor-derived mesenchymal stem-like cells (tMSLCs) promote the invasiveness of GBM tumorspheres (TSs). Here, we extend these studies in terms of ventricles using several types of GBM patient-derived cells. MATERIALS
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Growth kinetics of the sputtered Ni-30Cr-5Al alloy nanograins: Effects of Y addition and oxidationSurface & Coatings Technology (IF 4.865) Pub Date : 2023-02-28 ,DOI:10.1016/j.surfcoat.2023.129360Zongxiang Huang, Chang Su, Yun Xie, Xiao PengThe grain growth of the sputtered Ni-30Cr-5Al and Ni-30Cr-5Al-1Y (wt%) nanocrystalline alloys during temperature rising to and isothermally holding at 1000 °C in Ar has been investigated by transmission electron microscope (TEM). The thermal-induced grain growth of the two alloys at 1000 °C follows a law of dn − d0n = kt but the Y presence results in an increase of n from 3.46 to 3.95. This is attributed ...
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Growth kinetics of the sputtered Ni-30Cr-5Al alloy nanograins: Effects of Y addition and oxidationSurface and Coatings Technology Pub Date : 2023-02-28 ,DOI:10.1016/j.surfcoat.2023.129360Zongxiang Huang, Chang Su, Yun Xie, Xiao PengThe grain growth of the sputtered Ni-30Cr-5Al and Ni-30Cr-5Al-1Y (wt%) nanocrystalline alloys during temperature rising to and isothermally holding at 1000 °C in Ar has been investigated by transmission electron microscope (TEM). The thermal-induced grain growth of the two alloys at 1000 °C follows a law of dn − d0n = kt but the Y presence results in an increase of n from 3.46 to 3.95. This is attributed ...
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Recent advances in carbon-based nanomaterials for multivalent-ion hybrid capacitors: a reviewEnergy & Environmental Science (IF 39.714) Pub Date : 2023-02-27 ,DOI:10.1039/d2ee03719jXuan Gao, Haoyu Wu, Chang Su, Chuanming Lu, Yuhang Dai, Siyu Zhao, Xueying Hu, Fangjia Zhao, Wei Zhang, Ivan P. Parkin, Claire J. Carmalt, Guanjie He
Hybrid capacitors are emerging because of their ability to store large amounts of energy, cycle through charges quickly, and maintain stability even in harsh environments or at extreme temperatures. Hybrid capacitors with monovalent cations such as Li+, Na+, and K+ have been extensively studied. However, the flammable nature of organic electrolytes and the reactive alkali metallic electrodes have raised
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Comparison of mycology between different types of chronic rhinosinusitis.Journal of the Chinese Medical Association : JCMA Pub Date : 2023-02-23 ,DOI:10.1097/jcma.0000000000000905Rong-San Jiang,Mao-Chang Su
BACKGROUND The aim of this study was to culture fungi from the nasal discharge of patients with chronic rhinosinusitis (CRS) using both a traditional and Ponikau et al's method, and subsequently compare the culture results between CRS with nasal polyps (CRSwNPs) and without nasal polyps (CRSsNPs), and between eosinophilic and noneosinophilic CRS. METHODS Eighty-one CRS patients with CRS who underwent
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Single-cell transcriptomic atlas of Alzheimer's disease middle temporal gyrus reveals region, cell type and sex specificity of gene expression with novel genetic risk for MERTK in femalemedRxiv - Neurology Pub Date : 2023-02-23 ,DOI:10.1101/2023.02.18.23286037Le Zhang, Chuan Hua He, Sarah Coffey, Dominic Yin, I-Uen Hsu, Chang Su, Yixuan Ye, Chi Zhang, Joshua Spurrier, LaShae Nicholson, Carla V Rothlin, Sourav Ghosh, Pallavi P Gopal, David A Hafler, Hong-yu Zhao, Stephen M. Strittmatter
Alzheimer's disease, the most common age-related neurodegenerative disease, is closely associated with both amyloid-β plaque and neuroinflammation. Two thirds of Alzheimer's disease patients are females and they have a higher disease risk. Moreover, women with Alzheimer's disease have more extensive brain histological changes than men along with more severe cognitive symptoms and neurodegeneration
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Corrigendum to “Assessing the health risk of hyperuricemia in participants with persistent organic pollutants exposure - a systematic review and meta-analysis” [Ecotoxicol. Environ. Saf. 251 (Feb 2023) 114525]Ecotoxicology and Environmental Safety (IF 7.129) Pub Date : 2023-02-20 ,DOI:10.1016/j.ecoenv.2023.114661Yipei Yu, Xuyuan Quan, Huijun Wang, Bing Zhang, Chang Su, Yan HouAbstract not available ...
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Interpretable Medical Image Visual Question Answering via Multi-Modal Relationship Graph LearningarXiv - CS - Computer Vision and Pattern Recognition Pub Date : 2023-02-19 ,DOI:arxiv-2302.09636Xinyue Hu, Lin Gu, Kazuma Kobayashi, Qiyuan An, Qingyu Chen, Zhiyong Lu, Chang Su, Tatsuya Harada, Yingying ZhuMedical visual question answering (VQA) aims to answer clinically relevant questions regarding input medical images. This technique has the potential to improve the efficiency of medical professionals while relieving the burden on the public health system, particularly in resource-poor countries. Existing medical VQA methods tend to encode medical images and learn the correspondence between visual ...
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Effect of particle morphology on the fast-charging properties of high-nickel cathode materialsKorean Journal of Chemical Engineering (IF 3.146) Pub Date : 2023-02-18 ,DOI:10.1007/s11814-023-1386-2Yang Soo Kim, Jongmin Kim, Chang-Su Kim, Yong Min Kwon, Seong In Kim, Ji-Yong EomIn order to investigate the effect of the particle morphology on the fast-charging characteristics of high-nickel layered-cathode materials, single-crystalline and secondary-particle type cathode with different primary/secondary particle sizes were synthesized via careful microstructure design. The effect of crystalline and particle size on the fast-charging performance was identified by comparing ...
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Autophagy impairment in patients with obstructive sleep apnea modulates intermittent hypoxia-induced oxidative stress and cell apoptosis via hypermethylation of the ATG5 gene promoter regionEuropean Journal of Medical Research (IF 4.981) Pub Date : 2023-02-17 ,DOI:10.1186/s40001-023-01051-4Yung-Che Chen, I-Chun Lin, Mao-Chang Su, Po-Yuan Hsu, Chang-Chun Hsiao, Te-Yao Hsu, Chia-Wei Liou, Yu-Mu Chen, Chien-Hung Chin, Ting-Ya Wang, Jen-Chieh Chang, Yong-Yong Lin, Chiu-Ping Lee, Meng-Chih LinAutophagy is a catabolic process that recycles damaged organelles and acts as a pro-survival mechanism, but little is known about autophagy dysfunction and epigenetic regulation in patients with obstructive sleep apnea (OSA). Protein/gene expressions and DNA methylation levels of the autophagy-related genes (ATG) were examined in blood leukocytes from 64 patients with treatment-naïve OSA and 24 subjects ...
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Experimental and theoretical investigations of dispersion of ultrasonic waves in the low-temperature and low-pressure nitrogen gasThe Journal of the Acoustical Society of America (IF 2.482) Pub Date : 2023-02-03 ,DOI:10.1121/10.0017097Guanwen Sun, Hanyin Cui, Chao Li, Weijun Lin, Chang SuTemperature has a complex effect on acoustic dispersion in dilute gases. In this paper, the effect of temperature on the acoustic dispersion of dilute gases is analyzed theoretically and experimentally. Theoretically, the Navier–Stokes (NS) equation and the Greenspan's theory, which includes the rotational-relaxation correction, are applied to calculate the dispersive sound speed. It is concluded that ...
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Heterogeneous Epoxidation of Microcrystalline Cellulose and the Toughening Effect toward Epoxy ResinIndustrial & Engineering Chemistry Research (IF 4.326) Pub Date : 2023-02-01 ,DOI:10.1021/acs.iecr.2c03919Chang Su, Jianfang Guo, Jue Cheng, Junying Zhang, Feng GaoMicrocrystalline cellulose (MCC) is regarded as a potential filler in the fabrication of epoxy composites. However, MCC’s hydrophilic nature and strong hydrogen bonds caused by abundant surface hydroxyl groups greatly weaken its compatibility with the epoxy resin. In addition, it remains a challenge to efficiently and heterogeneously modify MCC surface hydroxyl groups. In this work, MCC was epoxidized ...
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Recognition of galactose by a scaffold protein recruits a transcriptional activator for the GAL regulon induction in Candida albicanseLife (IF 8.713) Pub Date : 2023-02-01 ,DOI:https://doi.org/10.7554/elife.84155Xun Sun, Jing Yu, Cheng Zhu, Xinreng Mo, Qiangqiang Sun, Dandan Yang, Chang Su, Yang LuThe GAL pathway of yeasts has long served as a model system for understanding of how regulatory mode of eukaryotic metabolic pathways evolves. While Gal4 mode has been well-characterized in Saccharomycetaceae clade, little is known about the regulation of the GAL pathway in other yeasts. Here, we find that Rep1, a Ndt80-like family transcription factor, serves as a galactose sensor in the commensal-pathogenic ...
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Status of the Newborn Hearing Screening in the 4-Months Age National Infant Health Checkup in Korea: A Nationwide Population-Based Study.Journal of Korean Medical Science (IF 5.354) Pub Date : 2023-01-30 ,DOI:10.3346/jkms.2023.38.e29Jiwon Chang,Su-Kyoung Park,Gi Jung Im,Joong Ho Ahn,Jun Ho Lee,Kyungdo Han,Jong Woo Chung,Jin-Sook Kim,Hyunsook Jang,Seung Hwan Lee
BACKGROUND The aims of this study are to review data on 4-months age National Health Screening Program for Infants and Children (NHSPIC) using a National Health Insurance Service (NHIS) database, and to analyze the newborn hearing screening (NHS) results and related characteristics of the 4-months NHSPIC for 7 years in South Korea. METHODS We analyzed a NHIS database of infants who had participated
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Comparison of the efficacy of focused ultrasound at different focal depths in treating vulvar lichen sclerosusInternational Journal of Hyperthermia (IF 3.753) Pub Date : 2023-01-29 ,DOI:10.1080/02656736.2023.2172220Ru Jia, Can Wu, Xiaoxu Tang, Miaomiao He, Xinglin Liu, Chang Su, Chengzhi Li
Abstract Objective This study aimed to compare the efficacy and safety of focused ultrasound (FU) at different focal depths in treating vulvar lichen sclerosus (VLS). Methods A retrospective study was conducted on 84 patients with VLS. Among them, 43 cases were treated with FU at a focal depth of 2.5 mm and 41 cases at a focal depth of 4.0 mm. Therapeutic time, treatment energy, postoperative efficacy
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An Evaluation Approach of Community Emergency Management Ability Based on Cone-ANP.International Journal of Environmental Research and Public Health (IF 4.614) Pub Date : 2023-01-28 ,DOI:10.3390/ijerph20032351Kai Wang,Yuanyuan Feng,Jun Deng,Chang Su,Quanfang Li
In order to improve the emergency management ability of urban communities in response to emergencies and reduce the losses caused by emergencies, based on the method of Cone-Analytic Network Process (Cone-ANP), a whole-process community emergency management ability evaluation method was proposed. Using around 25 evaluation indexes from six dimensions, namely infrastructure resilience, community organization
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The Efficacy of Using Patient-Derived Organoids to Predict Treatment Response in Colorectal Cancer.Cancers (IF 6.575) Pub Date : 2023-01-28 ,DOI:10.3390/cancers15030805Chang Su,Kelly A Olsen,Catherine E Bond,Vicki L J Whitehall
Colorectal cancer is an important cause of morbidity and mortality worldwide. The current treatment landscape includes chemotherapy, targeted therapy, immunotherapy, radiotherapy, and surgery. A key challenge to improving patient outcomes is the significant inter-patient heterogeneity in treatment response. Tumour organoids derived from the patients' tumours via surgically resected or endoscopically
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