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Integrating science to find cures in child neurology. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-04-01 Masayuki Sasaki
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Unraveling the etiological complexity of autism spectrum disorders. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-04-01 Arnold Munnich
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Fostering research pathways to positive long-term outcomes for childhood-onset epilepsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-03-07 Kathy Nixon Speechley
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Validity of a meta-analysis of risk factors for neonatal brachial plexus palsies. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-03-07 Andreas Rehm,Azeem Thahir
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Anteroposterior balance reactions in children with spastic cerebral palsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-03-02 Jeremy R Crenshaw,Drew A Petersen,Benjamin C Conner,James B Tracy,Jamie Pigman,Henry G Wright,Freeman Miller,Curtis L Johnson,Christopher M Modlesky
AIM To compare anterior and posterior standing balance reactions, as measured by single-stepping thresholds, in children with and without spastic cerebral palsy (CP). METHOD Seventeen ambulatory children with spastic CP (eight males, nine females) and 28 typically developing children (13 males, 15 females; age range 5-12y, mean [SD] 9y 2mo [2y 3mo]), were included in this cross-sectional, observational
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Knee pain in children with cerebral palsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-03-02 Henry G Chambers
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Non-motor symptoms in movement disorders: more than meets the eye. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-03-02 Federico Vigevano
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The child with medical complexity: Everybody's patient, Nobody's responsibility. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-03-01 Hilary Cass
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How useful is the diagnosis of ataxic cerebral palsy? Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-03-01 Bernard Dan
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Neural activation within the sensorimotor cortices during bimanual tasks in children with unilateral cerebral palsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-26 Swati M Surkar
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Transcranial magnetic stimulation as a biomarker of treatment response in children with epilepsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-24 Simona Balestrini,Josemir W Sander
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Questionnaires as screening tools for children with cerebral visual impairment. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-21 Elisa Fazzi,Serena Micheletti
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Does non-invasive ventilation compared to invasive ventilation improve short term survival for acute respiratory failure in people with neuromuscular disease and chest wall disorders? A Cochrane Review summary with commentary. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-20 Julia Patrick Engkasan,Soo Chin Chan
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Effect of neonatal therapy on the motor, cognitive, and behavioral development of infants born preterm: a systematic review. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-19 Sonia Khurana,Audrey E Kane,Shaaron E Brown,Talicia Tarver,Stacey C Dusing
AIM To synthesize the existing literature and determine the efficacy of neonatal therapy, starting in the neonatal intensive care unit (NICU), on the motor, cognitive, and behavioral outcomes of infants born preterm. METHOD Databases were searched for randomized controlled trials or quasi-randomized controlled trials of direct therapy early intervention for infants with a gestational age of less than
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Coaching approaches in early intervention and paediatric rehabilitation. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-17 Schirin Akhbari Ziegler,Mijna Hadders-Algra
Currently, coaching is increasingly applied to foster the involvement of families with an infant or young child with special needs in early intervention and paediatric rehabilitation. Coaching practices are included in many forms of intervention and are regarded as essential to reach beneficial outcomes for the child and family. There are, however, many ambiguities that blur the concept of coaching
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Health-related quality of life and upper-limb impairment in children with cerebral palsy: developing a mapping algorithm. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-16 Utsana Tonmukayakul,Christine Imms,Cathrine Mihalopoulos,Dinah Reddihough,Rob Carter,Brendan Mulhern,Gang Chen
AIM To: (1) investigate the relationship between upper-limb impairment and health-related quality of life (HRQoL) for children with cerebral palsy and (2) develop a mapping algorithm from the Cerebral Palsy Quality of Life Questionnaire for Children (CPQoL-Child) onto the Child Health Utility 9D (CHU9D) measure. METHOD The associations between physical and upper-limb classifications and HRQoL of 76
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Cortical excitability measured with transcranial magnetic stimulation in children with epilepsy before and after antiepileptic drugs. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-16 Ann-Charlotte Andreasson,Gudmundur V Sigurdsson,Göran Pegenius,Magnus Thordstein,Tove Hallböök
AIM To evaluate cortical excitability with transcranial magnetic stimulation (TMS) in children with new-onset epilepsy before and after antiepileptic drugs (AEDs). METHOD Fifty-five drug-naïve patients (29 females, 26 males; 3-18y), with new-onset epilepsy were recruited from 1st May 2014 to 31st October 2017 at the Child Neurology Department, Queen Silvia's Children's Hospital, Gothenburg, Sweden
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Callosal agenesis and congenital mirror movements: outcomes associated with DCC mutations. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-14 Megan Spencer-Smith,Jacquelyn L Knight,Emmanuelle Lacaze,,Christel Depienne,Paul J Lockhart,Linda J Richards,Delphine Heron,Richard J Leventer,Gail A Robinson
Pathogenic variants in the gene encoding deleted in colorectal cancer (DCC) are the first genetic cause of isolated agenesis of the corpus callosum (ACC). Here we present the detailed neurological, brain magnetic resonance imaging (MRI), and neuropsychological characteristics of 12 individuals from three families with pathogenic variants in DCC (aged 8-50y), who showed ACC and mirror movements (n=5)
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Intracranial hypertension and cortical thickness in syndromic craniosynostosis. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-14 Alexander T Wilson,Bianca K Den Ottelander,Robbin De Goederen,Marie-Lise C Van Veelen,Marjolein H G Dremmen,John A Persing,Henri A Vrooman,Irene M J Mathijssen
AIM To evaluate the impact of risk factors for intracranial hypertension (ICH) on cerebral cortex thickness in syndromic craniosynostosis. METHOD ICH risk factors including papilloedema, hydrocephalus, obstructive sleep apnea (OSA), cerebellar tonsillar position, occipitofrontal circumference (OFC) curve deflection, age, and sex were collected from the records of patients with syndromic craniosynostosis
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Predictors of cognitive development in children with neurofibromatosis type 1 and plexiform neurofibromas. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-12 Yang Hou,Taryn Allen,Pamela L Wolters,Mary Anne Toledo-Tamula,Staci Martin,Andrea Baldwin,Stephanie Reda,Andy Gillespie,Anne Goodwin,Brigitte C Widemann
AIM To describe the cognitive development of children with neurofibromatosis type 1 (NF1) and plexiform neurofibromas, and identify predictors of cognitive development. METHOD Participants included 88 children with NF1 and plexiform neurofibromas (50 males, 38 females, aged 6-18y, mean=12y, SD=3y 7mo) on a natural history study at the National Cancer Institute. Neuropsychological assessments (e.g.
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Corticosteroids and ACTH for infantile spasms: are we closer to equipoise? Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-12 Sarah Aminoff Kelley
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The Bangladesh Cerebral Palsy Register: the value of surveillance. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-11 Tanya Bedard
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Validity of the Ages and Stages Questionnaire to identify young children with gross motor difficulties who require physiotherapy assessment. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-11 John R Fauls,Bronwyn L Thompson,Leanne M Johnston
AIM To determine if the Ages and Stages Questionnaire, Third Edition Gross Motor domain (ASQ-3-GM) score is predictive of motor performance on the Alberta Infant Motor Scale (AIMS) and/or Neurological, Sensory, Motor, Developmental Assessment (NSMDA). METHOD This was a cross-sectional study involving analysis of a 1-year consecutive clinical sample of data obtained from children attending a specialist
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Precision neuroimaging in cerebral palsy: are we there yet? Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-11 Kshitij Mankad
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Quality of life cannot be predicted from a brain scan. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-09 Nora Fayed,Eyal Cohen,Amy Houtrow
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Brain activation patterns underlying upper limb bilateral motor coordination in unilateral cerebral palsy: an fNIRS study. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-07 Ana Carolina de Campos,Theresa Sukal-Moulton,Theodore Huppert,Katharine Alter,Diane L Damiano
AIM To explore cortical activation during bimanual tasks and functional correlates in unilateral cerebral palsy (CP). METHOD This cross-sectional study included eight participants with unilateral CP (six females, two males; mean age [SD] 20y 10mo [5y 10mo], 13y 8mo-31y 6mo) in Manual Ability Classification System levels II to III and nine age-matched participants with typical development (seven females
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Social impairments in alternating hemiplegia of childhood. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-07 Julie Uchitel,Elie Abdelnour,April Boggs,Lyndsey Prange,Milton Pratt,Melanie Bonner,Joan Jasien,Geraldine Dawson,Tavis Abrahamsen,Mohamad A Mikati
AIM To evaluate presence and severity of social impairments in alternating hemiplegia of childhood (AHC) and determine factors that are associated with social impairments. METHOD This was a retrospective analysis of 34 consecutive patients with AHC (19 females, 15 males; mean age: 9y 7mo, SD 8y 2mo, range 2y 7mo-40y), evaluated with the Social Responsiveness Scale, Second Edition (SRS-2). RESULTS SRS-2
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Developing more clinically useful biomarkers in autism spectrum disorder. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-01 Thomas W Frazier,Matthew S Goodwin
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Treatment of status epilepticus in children: where in the world are we now? Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-02-01 Jo M Wilmshurst
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Use of family disability service by families with young children with disabilities. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-31 Matthew Joseph Russell,Yunqi Zhang,Xinjie Cui,Suzanne Tough,Jennifer D Zwicker
AIM To investigate which families with young children with disabilities used disability services and when they used services to inform policy on service delivery. METHOD We used linked administrative data from different ministries in Alberta to describe families' use of disability services when their children were between the ages of 3 and 8 years old. Disability was investigated on the basis of the
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Wearable electromyography recordings during daily life activities in children with cerebral palsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-27 Josephine S Michelsen,Mai C Lund,Tine Alkjaer,Taija Finni,Jens B Nielsen,Jakob Lorentzen
AIM To test whether wearable textile electromyography (EMG) recording systems may detect differences in muscle activity levels during daily activities between children with cerebral palsy (CP) and age-matched typically developing children. METHOD Wearable textile EMG recording systems were used to obtain leg muscle activity in 10 children with spastic CP (four females, six males; mean age 9y 6mo, standard
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Psychosocial and functional outcomes in young adults with childhood-onset epilepsy: a 10-year follow-up. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-27 Rachel Friefeld Kesselmayer,Taylor McMillan,Beatrice Lee,Dace Almane,Bruce P Hermann,Jana E Jones
AIM To compare long-term psychosocial and functional outcomes of young adults with uncomplicated childhood-onset epilepsy (COE) to population norm controls utilizing a controlled prospective cohort study. METHOD Psychosocial and functional outcomes were assessed at 10-year follow-up. Fifty-three young adults (27 males, 26 females) with COE (n=21 remission; 18y 1mo-30y 9mo; mean age 23y 4mo [SD 3y 4mo];
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Long QT interval in Rett syndrome: expanding the knowledge of a poorly understood phenomenon. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-27 Walter E Kaufmann
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ICF mobility and self-care goals of children in inpatient rehabilitation. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-26 Fabian M Rast,Rob Labruyère
AIM To develop a detailed priority list of family-centred rehabilitation goals on the activity level within the International Classification of Functioning, Disability and Health (ICF) chapters d4 'Mobility' and d5 'Self-care' in a paediatric population with a broad range of health conditions. METHOD Twenty-two months after implementing a systematic, family-centred, goal-setting process, the rehabilitation
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Who sets the goals in pediatric rehabilitation? Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-26 Naomi Gefen
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Assessing participation of children with acquired brain injury and cerebral palsy: a systematic review of measurement properties. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-23 Christine Resch,Mette Van Kruijsbergen,Marjolijn Ketelaar,Petra Hurks,Brooke Adair,Christine Imms,Arend De Kloet,Barbara Piskur,Caroline Van Heugten
AIM To examine which instruments used to assess participation of children with acquired brain injury (ABI) or cerebral palsy (CP) align with attendance and/or involvement constructs of participation; and to systematically review measurement properties of these instruments in children with ABI or CP, to guide instrument selection. METHOD Five databases were searched. Instruments that quantified 'attendance'
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A neglected population in the study of children with HIV infection and stroke. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-23 Laura A Benjamin
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Quality of life in children: the use of parent reports. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-23 Hans M Koot
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Brain magnetic resonance imaging is a predictor of bimanual performance and executive function in children with unilateral cerebral palsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-22 Alison Crichton,Michael Ditchfield,Stellamay Gwini,Margaret Wallen,Megan Thorley,Jenny Bracken,Adrienne Harvey,Catherine Elliott,Iona Novak,Brian Hoare
AIM To examine the association between brain magnetic resonance imaging (MRI) characteristics and executive function and bimanual performance in children with unilateral cerebral palsy (CP). METHOD Clinical MRI brain scans were classified as: (1) predominant pathological pattern (normal, white matter injury [WMI]; grey matter injury; focal vascular insults [FVI]; malformations; or miscellaneous); and
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Is botulinum toxin effective and safe for motor and phonic tics in patients affected by Tourette syndrome? A Cochrane Review summary with commentary. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-20 Antimo Moretti
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Neurodevelopmental assessments of rare genetic conditions. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-10 Srinivas Gada
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Cognitive functioning in children with cerebral palsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-09 Kristine Stadskleiv
Children with cerebral palsy (CP) have an increased risk of cognitive impairments. This narrative review of the literature discusses assessment of cognition in children with CP, presents the most salient characteristics of cognitive functioning pertaining to each subtype, and discusses the relationships between brain injury, functioning, and intervention from a developmental perspective. A search for
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Epilepsy surgery: more to treatment outcomes than counting seizures. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-09 Sophia Varadkar
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Stroke transcranial Doppler in children with human immunodeficiency virus. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-08 Nomazulu Dlamini,Keith Pohl,Brian Eley,Ronald Van Toorn,Tracy Kilborn,Soundrie Padayachee,Ann-Marie Pontigon,Fenella J Kirkham,Jo Wilmshurst
AIMS To describe stroke syndromes and transcranial Doppler (TCD) findings in children with human immunodeficiency virus (HIV) and examine the associations between TCD and clinical and laboratory data. METHOD We enrolled 42 children (24 males, 18 females) with HIV (median age=7y 6mo; 2y 7mo-15y 6mo), with and without stroke who underwent a TCD examination of the anterior and posterior circulations to
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The effectiveness of felbamate for drug-resistant infantile spasms. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-08 Andrew Lux
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British Paediatric Neurology Association Annual Meeting, 29-31 January 2020, Assembly Buildings, Belfast. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2020-01-01
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Participation in leisure activities in adolescents with congenital heart defects. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2019-12-03 Annette Majnemer,Charles Rohlicek,Noemi Dahan-Oliel,Sossy Sahakian,Barbara Mazer,Désirée B Maltais,Norbert Schmitz
AIM To describe leisure participation in adolescents with congenital heart defects (CHD) and identify factors associated with intensity of participation. METHOD Eighty adolescents with CHD were recruited (39 males, 41 females; mean age [SD] 15y 8mo [1y 8mo] range 11y 5mo-19y 11mo) of whom 78 completed the Children's Assessment of Participation and Enjoyment (CAPE) outcome measure of leisure participation
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Vein of Galen malformation: beyond life or death. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2019-12-03 Vijeya Ganesan
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Complementary and alternative therapies: what are our responsibilities? Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2019-12-01 Peter Rosenbaum
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DMCN 2019 highlights: medical cannabis, developmental coordination disorder guidelines, cardiovascular disease in cerebral palsy, and more. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2019-12-01 Bernard Dan
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Use of the Dyskinesia Impairment Scale in non-ambulatory dyskinetic cerebral palsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2019-11-29 Helga Haberfehlner,Laura A Bonouvrié,Karin Boeschoten,Sabine Fleuren,Elegast Monbaliu,Jules G Becher,R Jeroen Vermeulen,Annemieke I Buizer
AIM To assess the responsiveness, concurrent validity, and feasibility of the Dyskinesia Impairment Scale (DIS) in non-ambulatory patients with dyskinetic cerebral palsy (CP). METHOD The study is a secondary analysis of data collected in the IDYS trial, a randomized controlled trial on the effects of intrathecal baclofen (ITB). The DIS and Barry-Albright Dystonia Scale (BADS) were conducted at baseline
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In support of selective dorsal rhizotomy in cerebral palsy: the strength of clinical experience. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2019-11-29 T S Park
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The expanding spectrum of movement disorders in genetic epilepsies. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2019-11-29 Apostolos Papandreou,Federica Rachele Danti,Robert Spaull,Vincenzo Leuzzi,Amy Mctague,Manju A Kurian
An ever-increasing number of neurogenetic conditions presenting with both epilepsy and atypical movements are now recognized. These disorders within the 'genetic epilepsy-dyskinesia' spectrum are clinically and genetically heterogeneous. Increased clinical awareness is therefore necessary for a rational diagnostic approach. Furthermore, careful interpretation of genetic results is key to establishing
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Potassium citrate supplementation with ketogenic dietary therapy for drug-resistant epilepsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2019-11-28 N E Schoeler
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Health-related quality of life, pain, and fatigue in young adults with cerebral palsy. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2019-11-28 Dan N O Jacobson,Kristina Löwing,Kristina Tedroff
AIM To describe health-related quality of life (HRQoL), pain, fatigue, and other health variables in young adults with cerebral palsy (CP), and to explore associations with the Gross Motor Function Classification System - Expanded and Revised (GMFCS-ER) and physical activity. METHOD This was a cross-sectional study of 61 young adults at a mean age of 21 years 2 months (standard deviation 8mo, range
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The long view of epilepsy and depression in pediatrics. Dev. Med. Child Neurol. (IF 4.406) Pub Date : 2019-11-25 Jay A Salpekar
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