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Largely reduced OAR doses, and planning and delivery times for challenging robotic SBRT cases, obtained with a novel optimizer J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-21 Marta K. Giżyńska; Linda Rossi; Wilhelm den Toom; Maaike T. W. Milder; Kim C. de Vries; Joost Nuyttens; Ben J. M. Heijmen
Recently, VOLO™ was introduced as a new optimizer for CyberKnife® planning. In this study, we investigated possibilities to improve treatment plans for MLC‐based prostate SBRT with enhanced peripheral zone dose while sparing the urethra, and central lung tumors, compared to existing Sequential Optimization (SO). The primary focus was on reducing OAR doses. For 25 prostate and 25 lung patients treated
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A preliminary investigation of re‐evaluating the irradiation dose in hepatocellular carcinoma radiotherapy applying 4D CT and deformable registration J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-15 Hua Xu; Guanzhong Gong; Yong Yin; Tonghai Liu
To investigate the effect of breathing motion on dose distribution for hepatocellular carcinoma (HCC) patients using four‐dimensional (4D) CT and deformable registration.
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Unlocking a closed system: dosimetric commissioning of a ring gantry linear accelerator in a multivendor environment J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-15 Amarjit Saini; Chris Tichacek; William Johansson; Gage Redler; Geoffrey Zhang; Eduardo G. Moros; Muqeem Qayyum; Vladimir Feygelman
The Halcyon™ platform is self‐contained, combining a treatment planning (Eclipse) system TPS) with information management and radiation delivery components. The standard TPS beam model is configured and locked down by the vendor. A portal dosimetry‐based system for patient‐specific QA (PSQA) is also included. While ensuring consistency across the user base, this closed model may not be optimal for
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Fetal radiation dose of four tube voltages in abdominal CT examinations during pregnancy: A phantom study J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-15 Yuta Matsunaga; Tomonobu Haba; Masanao Kobayashi; Shoichi Suzuki; Yasuki Asada; Koichi Chida
This study aimed to compare the dose and noise level of four tube voltages in abdominal computerized tomography (CT) examinations in different abdominal circumference sizes of pregnant women. Fetal radiation doses were measured with two anthropomorphic pregnant phantoms and real‐time dosimeters of photoluminescence sensors using four tube voltages for abdominal CT. The noise level was measured at the
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MRI evaluation of normal tissue deformation and breathing motion under an abdominal compression device J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-15 Maureen Lee; Anna Simeonov; Teo Stanescu; Laura A. Dawson; Kristy K. Brock; Michael Velec
Abdominal compression can minimize breathing motion in stereotactic radiotherapy, though it may impact the positioning of dose‐limiting normal tissues. This study quantified the reproducibility of abdominal normal tissues and respiratory motion with the use of an abdominal compression device using MR imaging.
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Evaluation of diffusion‐weighted MRI and geometric distortion on a 0.35T MR‐LINAC at multiple gantry angles J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-15 Benjamin Lewis; Anamaria Guta; Stacie Mackey; H. Michael Gach; Sasa Mutic; Olga Green; Taeho Kim
Diffusion‐weighted imaging (DWI) provides a valuable diagnostic tool for tumor evaluation. Yet, it is difficult to acquire daily MRI data sets in the traditional radiotherapy clinical setting due to patient burden and limited resources. However, integrated MRI radiotherapy treatment systems facilitate daily functional MRI acquisitions like DWI during treatment exams. Before ADC values from MR‐RT systems
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How low can you go? A CBCT dose reduction study J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-15 Arthur J. Olch; Parham Alaei
Cone beam computed tomography (CBCT) is often used for patient setup based solely on bony anatomy. The goal of this work was to evaluate whether CBCT dose can be lowered to the level of kV image pair doses when used for bony anatomy‐based IGRT without compromising positioning accuracy.
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Consistency of small‐field dosimetry, on and off axis, in beam‐matched linacs used for stereotactic radiosurgery J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-13 Luis Muñoz; Tomas Kron; Marco Petasecca; Joseph Bucci; Michael Jackson; Peter Metcalfe; Anatoly B. Rosenfeld; Giordano Biasi
Stereotactic radiosurgery (SRS) can be delivered with a standard linear accelerator (linac). At institutions having more than one linac, beam matching is common practice. In the literature, there are indications that machine central axis (CAX) matching for broad fields does not guarantee matching of small fields with side ≤2 cm. There is no indication on how matching for broad fields on axis translates
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The clinical impact of removing rectal gas on high‐dose‐rate brachytherapy dose distributions for gynecologic cancers J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-13 Irina Vergalasova; Ronald D. Ennis; Mutlay Sayan; Bo Liu; Ning J. Yue; Lara Hathout
To evaluate the impact of gas removal on bladder and rectal doses during intracavitary and interstitial high‐dose‐rate brachytherapy (HDRB) for gynecologic cancers.
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Automatic couch position calculation using eclipse scripting for external beam radiotherapy J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-13 Hesheng Wang; Anthony Rea; Benedikt Rudek; Ting Chen; Allison McCarthy; David Barbee
The treatment couch position of a patient in external beam radiation therapy (EBRT) is usually acquired during initial treatment setup. This procedure has shown potential failure modes leading to near misses and adverse events in radiation treatment. This study aims to develop a method to automatically determine the couch position before setting up a patient for initial treatment.
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Vendor‐independent skin dose mapping application for interventional radiology and cardiology J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-13 Marko Krajinović; Nikola Kržanović; Olivera Ciraj‐Bjelac
The purpose of this paper is to present and validate an originally developed application SkinCare used for skin dose mapping in interventional procedures, which are associated with relatively high radiation doses to the patient’s skin and possible skin reactions.
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Identification of robust and reproducible CT‐texture metrics using a customized 3D‐printed texture phantom J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-12 Bino A. Varghese; Darryl Hwang; Steven Y. Cen; Xiaomeng Lei; Joshua Levy; Bhushan Desai; David J. Goodenough; Vinay A. Duddalwar
The objective of this study was to evaluate the robustness and reproducibility of computed tomography‐based texture analysis (CTTA) metrics extracted from CT images of a customized texture phantom built for assessing the association of texture metrics to three‐dimensional (3D) printed progressively increasing textural heterogeneity.
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Reduction of superficial radiation dose with bolus in passive scattering proton beam therapy J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-12 Yeon‐Joo Kim; Chankyu Kim; Se Byeong Lee; Jae‐Sung Kim
In passive scattering proton beam therapy, scattered protons from the snout and aperture increase the superficial dose, however, treatment planning systems (TPSs) based on analytic algorithms (such as proton convolution superposition) are often inaccurate in this aspect. This additional dose can cause permanent alopecia or severe radiation dermatitis. This study aimed to evaluate the effect of bolus
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Integrating CVH and LVH metrics into an optimization strategy for the selection of Iris collimator for Cyberknife Xsight lung tracking treatment J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-11 Feng Xiao; Yu Chang; Sheng Zhang; Zhiyong Yang
We conducted this study to construct a target coverage‐volume histogram (CVH) and leakage‐volume histogram (LVH) metrics and optimization strategy for the selection of the Iris collimator in Cyberknife Xsight lung tracking treatment through a retrospective analysis of target structures and clinical data.
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Trajectory log analysis and cone‐beam CT‐based daily dose calculation to investigate the dosimetric accuracy of intensity‐modulated radiotherapy for gynecologic cancer J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-10 Yohei Utena; Jun Takatsu; Satoru Sugimoto; Keisuke Sasai
This study evaluated unexpected dosimetric errors caused by machine control accuracy, patient setup errors, and patient weight changes/internal organ deformations. Trajectory log files for 13 gynecologic plans with seven‐ or nine‐beam dynamic multileaf collimator (MLC) intensity‐modulated radiation therapy (IMRT), and differences between expected and actual MLC positions and MUs were evaluated. Effects
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Examination of the best head tilt angle to reduce the parotid gland dose maintaining a safe level of lens dose in whole‐brain radiotherapy using the four‐field box technique J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-10 Hidetoshi Shimizu; Koji Sasaki; Takahiro Aoyama; Hiroyuki Tachibana; Hiroshi Tanaka; Yutaro Koide; Tohru Iwata; Tomoki Kitagawa; Takeshi Kodaira
The parotid gland is recognized as a major‐risk organ in whole‐brain irradiation; however, the beam delivery from the left and right sides cannot reduce the parotid gland dose. The four‐field box technique using a head‐tilting device has been reported to reduce the parotid gland dose by excluding it from the radiation field. This study aimed to determine the appropriate head tilt angle to reduce the
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Experimental evaluation of the GE Discovery 870 CZT clinical SPECT system equipped with WEHR and MEHRS collimator J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-10 Toshimune Ito; Yohji Matsusaka; Masahisa Onoguchi; Hajime Ichikawa; Koichi Okuda; Takayuki Shibutani; Masaaki Shishido; Kozo Sato
A high‐energy‐resolution whole‐body SPECT‐CT device (Discovery NM/CT 870 CZT; C‐SPECT) equipped with a CZT detector has been developed and is being used clinically. A MEHRS collimator has also been developed recently, with an expected improvement in imaging accuracy using medium‐energy radionuclides. The objective of this study was to compare and analyze the accuracies of the following devices: a WEHR
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Investigating the feasibility of generating dual‐energy CT from one 120‐kVp CT scan: a phantom study J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-10 Wen‐Hui Huang; Kai‐Jie Jhan; Ching‐Ching Yang
This study aimed to investigate the feasibility of generating pseudo dual‐energy CT (DECT) from one 120‐kVp CT by using convolutional neural network (CNN) to derive additional information for quantitative image analysis through phantom study.
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Spectral CT quantification stability and accuracy for pediatric patients: A phantom study J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-10 Nadav Shapira; Kai Mei; Peter B. Noël
Spectral computed tomography (spectral CT) provides access to clinically relevant measures of endogenous and exogenous materials in patients. For pediatric patients, current spectral CT applications include lesion characterization, quantitative vascular imaging, assessments of tumor response to treatment, and more.
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Structured mentorship program for the ABR international medical graduates alternate pathway for medical physicists in diagnostic imaging J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-09 Francesco Ria; Joshua M. Wilson; Jeffrey Nelson; Ehsan Samei
According to the US Census Bureau, recent immigrants to the United States are more likely to have a college education than earlier immigrants or the native born.1 In particular, in 2018 13.9% of immigrants ages 25 and older hold a postgraduate degree2 compared to about 13.1% of US adults.1 However, in a highly technological discipline like medical physics, even the highest education needs to be integrated
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An electronic portal image device (EPID)‐based multiplatform rapid daily LINAC QA tool J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-07 Yangguang Ma; Xuemin Wang; Rizhen Mai; Tao Wang; Yuntong Pei; Shuaipeng Liu; Yuexin Guo
To develop an efficient and economic daily quality research tool (DQRT) for daily check of multiplatform linear accelerators (LINACs) with flattening filter (FF) and flattening filter‐free (FFF) photon beams by using an Electronic Portal Image Device (EPID).
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Performance of deep learning synthetic CTs for MR‐only brain radiation therapy J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-07 Xiaoning Liu; Hajar Emami; Siamak P. Nejad‐Davarani; Eric Morris; Lonni Schultz; Ming Dong; Carri K. Glide‐Hurst
To evaluate the dosimetric and image‐guided radiation therapy (IGRT) performance of a novel generative adversarial network (GAN) generated synthetic CT (synCT) in the brain and compare its performance for clinical use including conventional brain radiotherapy, cranial stereotactic radiosurgery (SRS), planar, and volumetric IGRT.
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Book review of artificial intelligence in medicine Edited by Lei Xing, Maryellen Giger, and James Min J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-05 Dandan Zheng
1 Overview The past decade has been a golden age for artificial intelligence (AI), with an explosive amount of research and development. From AlphaGo to self‐driving vehicles and brain–computer interface, transformative changes and bold ideas are sweeping through our everyday lives. One important application area is the field of medicine. In medicine, AI has also dominated scientific conferences in
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CT imaging of gold nanoparticles in a human‐sized phantom J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-05 Michael Oumano; Liz Russell; Morteza Salehjahromi; Lou Shanshan; Neeharika Sinha; Wilfred Ngwa; Hengyong Yu
Gold nanoparticles (AuNPs) are visualized and quantified in a human‐sized phantom with a clinical MDCT scanner.
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The future of radiation therapy J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-04 R. J. Schulz
Since the development of one‐ and two‐million volt x‐ray machines in the 1930s, which led to the reduction of both skin erythema and bone necrosis as well as an increase in depth dose, medical physicists have worked steadily to develop radiation sources and techniques for increasing the therapeutic ratios for most solid tumors. One of the major results of this research was the linear electron accelerator
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Initial testing of pegfilgrastim (Neulasta Onpro) on‐body injector in multiple radiological imaging environments J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-04 Zaiyang Long; Anil Nicholas Kurup; Nicole M. Jensen; Nicholas J. Hangiandreou; Beth A. Schueler; Lifeng Yu; Shuai Leng; Christopher P. Wood; Joel P. Felmlee
An increasing number of implantable or external devices can impact whether patients can receive radiological imaging examinations. This study examines and tests the Neulasta (pegfilgrastim) Onpro on‐body injector in multiple imaging environments.
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Dosimetric impact of the positioning variation of tumor treating field electrodes in the PriCoTTF‐phase I/II trial J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2021-01-03 Youness Nour; Christoph Pöttgen; Sied Kebir; Lazaros Lazaridis; Lutz Lüdemann; Maja Guberina; Thomas Gauler; Björn Scheffler; Ramazan Jabbarli; Daniela Pierscianek; Ulrich Sure; Teresa Schmidt; Christoph Oster; Peter Hau; Martin Glas; Wolfgang Lübcke; Martin Stuschke; Nika Guberina
The aim of the present study based on the PriCoTTF‐phase I/II trial is the quantification of skin‐normal tissue complication probabilities of patients with newly diagnosed glioblastoma multiforme treated with Tumor Treating Field (TTField) electrodes, concurrent radiotherapy, and temozolomide. Furthermore, the skin‐sparing effect by the clinically applied strategy of repetitive transducer array fixation
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Accuracy and efficiency of respiratory gating comparable to deep inspiration breath hold for pancreatic cancer treatment J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-12-30 Chuan Zeng; Xiang Li; Wei Lu; Marsha Reyngold; Richard M. Gewanter; John J. Cuaron; Ellen Yorke; Tianfang Li
Deep inspiration breath hold (DIBH) and respiratory gating (RG) are widely used to reduce movement of target and healthy organs caused by breathing during irradiation. We hypothesized that accuracy and efficiency comparable to DIBH can be achieved with RG for pancreas treatment.
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Spatial and dosimetric evaluation of residual distortions of prostate and seminal vesicle bed after image‐guided definitive and postoperative radiotherapy of prostate cancer with endorectal balloon J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-12-30 Sabine Levegrün; Christoph Pöttgen; Konstantinos Xydis; Maja Guberina; Jehad Abu Jawad; Martin Stuschke
To quantify daily residual deviations from the planned geometry after image‐guided prostate radiotherapy with endorectal balloon and to evaluate their effect on the delivered dose distribution.
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Effect of obesity on ability to lower exposure for detection of low‐attenuation liver lesions J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-12-28 Brian R. Herts; Andrew Schreiner; Frank Dong; Andrew Primak; Jennifer Bullen; Wadih Karim; Douglas Nachand; Sara Hunter; Mark E. Baker
The purpose of this study was to assess the effect of obesity and iterative reconstruction on the ability to reduce exposure by studying the accuracy for detection of low‐contrast low‐attenuation (LCLA) liver lesions on computed tomography (CT) using a phantom model.
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Differentiation of pulmonary sclerosing pneumocytoma from solid malignant pulmonary nodules by radiomic analysis on multiphasic CT J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-12-28 Xiao‐Qiong Ni; Hong‐kun Yin; Guo‐hua Fan; Dai Shi; Liang Xu; Dan Jin
To investigate the diagnostic value and feasibility of radiomics‐based texture analysis in differentiating pulmonary sclerosing pneumocytoma (PSP) from solid malignant pulmonary nodules (SMPN) on single‐ and three‐phase computed tomography (CT) images.
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Global trends in open access publication and open data J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-12-28 Michael Mills
This Editorial will summarize some of the recent tendencies of publication explored in a recent Wiley Society Newsletter on the open access movement: http://s1133198723.t.en25.com/e/es?s=1133198723&e=6599750&elqTrackId=be52ad97a9d24b6c8db9974cd2051faf&elq=fef810d97dae4c9c9b098792bf9de575&elqaid=48002&elqat=1 . As it turns out, in a recent survey about Society Publications, Wiley determined that no‐cost
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We are ready for clinical implementation of Carbon Ion Radiotherapy in the United States J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-12-14 Chris Beltran; Richard A. Amos; Yi Rong
1 INTRODUCTION In the past three decades, all carbon ion treatment centers are mainly located in Europe and Asia, yet the therapeutic benefits of carbon ion therapy were first discovered in the United States in 1970s. Clinical outcome studies are coming out in the recent years from those centers comparing carbon ion treatment with conventional photon radiotherapy or surgery.1, 2 People might have been
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Quantitative analysis of treatments using real‐time image gated spot‐scanning with synchrotron‐based proton beam therapy system log data J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-05 Takaaki Yoshimura; Shinichi Shimizu; Takayuki Hashimoto; Kentaro Nishioka; Norio Katoh; Hiroshi Taguchi; Koichi Yasuda; Taeko Matsuura; Seishin Takao; Masaya Tamura; Sodai Tanaka; Yoichi M. Ito; Yuto Matsuo; Hiroshi Tamura; Kenji Horita; Kikuo Umegaki; Hiroki Shirato
A synchrotron‐based real‐time image gated spot‐scanning proton beam therapy (RGPT) system with inserted fiducial markers can irradiate a moving tumor with high accuracy. As gated treatments increase the beam delivery time, this study aimed to investigate the frequency of intra‐field adjustments corresponding to the baseline shift or drift and the beam delivery efficiency of a synchrotron‐based RGPT
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Characterization of radiotherapy component impact on MR imaging quality for an MRgRT system J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-19 Benjamin C. Lewis; Bruce Gu; Ryan Klett; Rajiv Lotey; Olga L. Green; Taeho Kim
Radiotherapy components of an magnetic resonnace‐guided radiotherapy (MRgRT) system can alter the magnetic fields, causing spatial distortion and image deformation, altering imaging and radiation isocenter coincidence and the accuracy of dose calculations. This work presents a characterization of radiotherapy component impact on MR imaging quality in terms of imaging isocenter variation and spatial
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The quantification and potential impact of dark current on treatments with an MR‐guided radiotherapy (MRgRT) system J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-10-29 Andrew J. Shepard; Kathryn E. Mittauer; John E. Bayouth; Poonam Yadav
Dark current radiation produced during linac beam‐hold has the potential to lead to unplanned dose delivered to the patient. With the increased usage of motion management and step‐and‐shoot IMRT deliveries for MR‐guided systems leading to increased beam‐hold time, it is necessary to consider the impact of dark current radiation on patient treatments.
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Calculating and estimating second cancer risk from breast radiotherapy using Monte Carlo code with internal body scatter for each out‐of‐field organ J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-10-30 Takeshi Takata; Kenshiro Shiraishi; Shinobu Kumagai; Norikazu Arai; Takenori Kobayashi; Hiroshi Oba; Takahide Okamoto; Jun’ichi Kotoku
Out‐of‐field organs are not commonly designated as dose calculation targets during radiation therapy treatment planning, but they might entail risks of second cancer. Risk components include specific internal body scatter, which is a dominant source of out‐of‐field doses, and head leakage, which can be reduced by external shielding. Our simulation study quantifies out‐of‐field organ doses and estimates
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Effect of MU‐weighted multi‐leaf collimator position error on dose distribution of SBRT radiotherapy in peripheral non‐small cell lung cancer J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-10-31 AiHui Feng; Hua Chen; Hao Wang; HengLe Gu; Yan Shao; YanHua Duan; YanChen Ying; Ning Jeff Yue; ZhiYong Xu
Position accuracy of the multi‐leaf collimator (MLC) is essential in stereotactic body radiotherapy (SBRT). This study is aimed to investigate the dosimetric impacts of the MU‐weighted MLC positioning uncertainties of SBRT for patients with early stage peripheral non‐small cell lung cancer (NSCLC).
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Development of an HDR‐BT QA tool for source position verification J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-02 Yu Kumazaki; Ryuta Hirai; Mitsunobu Igari; Nao Kobayashi; Shohei Okazaki; Takanori Abe; Tomoaki Tamaki; Shin‐ei Noda; Shingo Kato
This study aimed to develop a high‐dose‐rate brachytherapy (HDR‐BT) quality assurance (QA) tool for verification of source positions, and to report on its effectiveness.
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Surface guided imaging during stereotactic radiosurgery with automated delivery J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-10-23 Elizabeth L. Covington; Dennis N. Stanley; John B. Fiveash; Evan M. Thomas; Samuel R. Marcrom; Marcus Bredel; Christopher D. Willey; Kristen O. Riley; Richard A. Popple
To report on the use of surface guided imaging during frameless intracranial stereotactic radiotherapy with automated delivery via HyperArcTM (Varian Medical Systems, Palo Alto, CA).
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Proton vs Hyperarc™ radiosurgery: A planning comparison J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-05 A. Boczkowski; P. Kelly; S. L. Meeks; K. Erhart; F. J. Bova; T. R. Willoughby
For many patients, stereotactic radiosurgery (SRS) offers a minimally invasive, curative option when surgical techniques are not possible. To date, the literature supporting the efficacy and safety of SRS treatment techniques uses photon beams. However, with the number of proton therapy facilities exponentially growing and the favorable physical properties of proton beam radiation therapy, there is
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A retrospective analysis of setup and intrafraction positional variation in stereotactic radiotherapy treatments J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-03 Micah Barnes; Adam Yeo; Kenton Thompson; Claire Phillips; Tomas Kron; Nicholas Hardcastle
The aim of this study was to provide a comprehensive assessment of patient intrafraction motion in linac‐based frameless stereotactic radiosurgery (SRS) and radiotherapy (SRT).
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Recommended dose voxel size and statistical uncertainty parameters for precision of Monte Carlo dose calculation in stereotactic radiotherapy J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-10-30 Simon K. Goodall; Martin A. Ebert
Monte Carlo (MC)‐based treatment planning requires a choice of dose voxel size (DVS) and statistical uncertainty (SU). These parameters effect both the precision of displayed dose distribution and time taken to complete a calculation. For efficient, accurate, and precise treatment planning in a clinical setting, optimal values should be selected. In this investigation, 30 volumetric modulated arc therapy
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Useful island block geometries of a passive intensity modulator used for intensity‐modulated bolus electron conformal therapy J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-18 Erin L. Chambers; Robert L. Carver; Kenneth R. Hogstrom
This project determined the range of island block geometric configurations useful for the clinical utilization of intensity‐modulated bolus electron conformal therapy (IM‐BECT).
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A study of the dosimetric impact of daily setup variations measured with cone‐beam CT on three‐dimensional conformal radiotherapy for early‐stage breast cancer delivered in the prone position J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-10-30 Annie Xiao; Jessica Jutzy; Greg Hubert; Meghan Edens; Maxine Washington; Yasmin Hasan; Steven J. Chmura; Hania A. Al‐Hallaq
To evaluate the dosimetric impact of daily positioning variations measured with cone‐beam computed tomography (CBCT) on whole‐breast radiotherapy patients treated in the prone position.
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Effect of setup error in the single‐isocenter technique on stereotactic radiosurgery for multiple brain metastases J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-10-29 Hisashi Nakano; Satoshi Tanabe; Satoru Utsunomiya; Takumi Yamada; Ryuta Sasamoto; Toshimichi Nakano; Hirotake Saito; Takeshi Takizawa; Hironori Sakai; Atsushi Ohta; Eisuke Abe; Motoki Kaidu; Hidefumi Aoyama
In conventional stereotactic radiosurgery (SRS), treatment of multiple brain metastases using multiple isocenters is time‐consuming resulting in long dose delivery times for patients. A single‐isocenter technique has been developed which enables the simultaneous irradiation of multiple targets at one isocenter. This technique requires accurate positioning of the patient to ensure optimal dose coverage
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Contextual loss based artifact removal method on CBCT image J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-02 Shipeng Xie; Yingjuan Liang; Tao Yang; Zhenrong Song
Cone beam computed tomography (CBCT) offers advantages such as high ray utilization rate, the same spatial resolution within and between slices, and high precision. It is one of the most actively studied topics in international computed tomography (CT) research. However, its application is hindered owing to scatter artifacts. This paper proposes a novel scatter artifact removal algorithm that is based
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Evaluation of cine imaging during multileaf collimator and gantry motion for real‐time magnetic resonance guided radiation therapy J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-23 Jerrold E. Kielbasa; Sanford L. Meeks; Patrick Kelly; Twyla R. Willoughby; Omar Zeidan; Amish P. Shah
Real‐time magnetic resonance guided radiation therapy (MRgRT) uses 2D cine imaging for target tracking. This work evaluates the percent image uniformity (PIU) and spatial integrity of cine images in the presence of multileaf collimator (MLC) and gantry motion in order to simulate sliding window and volumetric modulated arc therapy (VMAT) conditions.
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A phantom study to evaluate three different registration platform of 3D/3D, 2D/3D, and 3D surface match with 6D alignment for precise image‐guided radiotherapy J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-12 Hsiang‐Chi Kuo; Michael M. Lovelock; Guang Li; Åse Ballangrud; Brian Wolthuis; Cesar Della Biancia; Margie A. Hunt; Sean L. Berry
To evaluate two three‐dimensional (3D)/3D registration platforms, one two‐dimensional (2D)/3D registration method, and one 3D surface registration method (3DS). These three technologies are available to perform six‐dimensional (6D) registrations for image‐guided radiotherapy treatment.
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Secondary malignancy risk for patients with localized prostate cancer after intensity‐modulated radiotherapy with and without flattening filter J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-04 Marius Treutwein; Rainer Loeschel; Matthias Hipp; Oliver Koelbl; Barbara Dobler
Men treated for localized prostate cancer by radiotherapy have often a remaining life span of 10 yr or more. Therefore, the risk for secondary malignancies should be taken into account. Plans for ten patients were evaluated which had been performed on an Oncentra® treatment planning system for a treatment with an Elekta Synergy™ linac with Agility™ head. The investigated techniques involved IMRT and
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Monte Carlo simulation of 6‐MV dynamic wave VMAT deliveries by Vero4DRT linear accelerator using EGSnrc moving sources J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-21 Maryam Rostamzadeh; Yoshitomo Ishihara; Mitsuhiro Nakamura; I. Antoniu Popescu; Ante Mestrovic; Ermias Gete; Roberto Fedrigo; Alanah Mary Bergman
The commissioning and benchmark of a Monte Carlo (MC) model of the 6‐MV Brainlab‐Mitsubishi Vero4DRT linear accelerator for the purpose of quality assurance of clinical dynamic wave arc (DWA) treatment plans is reported. Open‐source MC applications based on EGSnrc particle transport codes are used to simulate the medical linear accelerator head components. Complex radiotherapy irradiations can be simulated
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Methodological approach to create an atlas using a commercial auto‐contouring software J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-25 Marta Casati; Stefano Piffer; Silvia Calusi; Livia Marrazzo; Gabriele Simontacchi; Vanessa Di Cataldo; Daniela Greto; Isacco Desideri; Marco Vernaleone; Giulio Francolini; Lorenzo Livi; Stefania Pallotta
The aim of this work was to establish a methodological approach for creation and optimization of an atlas for auto‐contouring, using the commercial software MIM MAESTRO (MIM Software Inc. Cleveland OH).
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Image quality evaluation of intra‐irradiation cone‐beam computed tomography acquired during one‐ and two‐arc prostate volumetric‐modulated arc therapy delivery: A phantom study J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-16 Hiraku Iramina; Ayaka Kitamura; Mitsuhiro Nakamura; Takashi Mizowaki
To evaluate (a) the effects of megavoltage (MV)‐scatter on concurrent kilovoltage (kV) projections (PMVkV) acquired during rotational delivery, and (b) the image quality of intra‐irradiation cone‐beam computed tomography (ii‐CBCT) images acquired during prostate volumetric‐modulated arc therapy (VMAT) delivery.
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A quality assurance tool for daily checks of the gamma knife high definition motion management system J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-18 Robert Corns; Dhara Mehta; Whitney Massock; Leah Roberts
This note describes the performance of a quality assurance (QA) tool built for daily checks of the Gamma Knife’s high definition motion management (HDMM) system.
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Stereotactic radiotherapy of appropriately selected meningiomas and metastatic brain tumor beds with gamma knife icon versus volumetric modulated arc therapy J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-18 Jacob S. Buatti; John M. Buatti; Sridhar Yaddanapudi; Edward C. Pennington; Dongxu Wang; Brandie Gross; Joël J. St‐Aubin; Daniel E. Hyer; Mark C. Smith; Ryan T. Flynn
To determine if the gamma knife icon (GKI) can provide superior stereotactic radiotherapy (SRT) dose distributions for appropriately selected meningioma and post‐resection brain tumor bed treatments to volumetric modulated arc therapy (VMAT).
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Effect of dental metal artifact conversion volume on dose distribution in head‐and‐neck volumetric‐modulated arc therapy J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-23 Kenta Kitagawa; Hitoshi Ikushima; Motoharu Sasaki; Shunsuke Furutani; Takashi Kawanaka; Akiko Kubo; Chisato Tonoiso; Takaharu Kudoh; Yosuke Kano; Akira Tsuzuki
During treatment planning for head‐and‐neck volumetric‐modulated arc therapy (VMAT), manual contouring of the metal artifact area of artificial teeth is done, and the area is replaced with water computed tomography (CT) values for dose calculation. This contouring of the metal artifact areas, which is performed manually, is subject to human variability. The purpose of this study is to evaluate and
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Refining complex re‐irradiation dosimetry through feasibility benchmarking and analysis for informed treatment planning J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-12-03 Seth R. Duffy; Yiran Zheng; Jessica Muenkel; Rodney J. Ellis; Tanvir N. Baig; Brian Krancevic; Christian B. Langmack; Kevin D. Kelley; Serah Choi
The purpose of this study is to dually evaluate the effectiveness of PlanIQ in predicting the viability and outcome of dosimetric planning in cases of complex re‐irradiation as well as generating an equivalent plan through Pinnacle integration. The study also postulates that a possible strength of PlanIQ lies in mitigating pre‐optimization uncertainties tied directly to dose overlap regions where re‐irradiation
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Evaluation of deep learning‐based auto‐segmentation algorithms for delineating clinical target volume and organs at risk involving data for 125 cervical cancer patients J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-11-25 Zhi Wang; Yankui Chang; Zhao Peng; Yin Lv; Weijiong Shi; Fan Wang; Xi Pei; X. George Xu
To evaluate the accuracy of a deep learning‐based auto‐segmentation mode to that of manual contouring by one medical resident, where both entities tried to mimic the delineation "habits" of the same clinical senior physician.
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Using flattening filter free beams in electronic tissue compensation whole breast irradiation with deep inspiration breath hold J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-12-03 Sarah B. Wisnoskie; Xiaoying Liang; Andrew O. Wahl; Nathan R. Bennion; Andrew D. Granatowicz; Sumin Zhou; Dandan Zheng
In order to reduce heart dose, DIBH has become a common practice in left‐sided whole breast irradiation. This technique involves a significant strain on patients due to the breath‐hold requirements. We hereby investigate the dosimetric and delivery feasibility of using flattening filter free (FFF) energies with electronic tissue compensation (ECOMP) planning technique to reduce the required breath‐hold
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Radiobiological effects of the interruption time with Monte Carlo Simulation on multiple fields in photon beams J. Appl. Clin. Med. Phys. (IF 1.679) Pub Date : 2020-12-03 Hisashi Nakano; Daisuke Kawahara; Satoshi Tanabe; Satoru Utsunomiya; Takeshi Takizawa; Madoka Sakai; Hirotake Saito; Atsushi Ohta; Motoki Kaidu; Hiroyuki Ishikawa
The interruption time is the irradiation interruption that occurs at sites and operations such as the gantry, collimator, couch rotation, and patient setup within the field in radiotherapy. However, the radiobiological effect of prolonging the treatment time by the interruption time for tumor cells is little evaluated. We investigated the effect of the interruption time on the radiobiological effectiveness