Purpose Ocular manifestations and ocular transmission of SARS-CoV-2 in contact lens (CL) wearers may be fostered by non-compliance with care and maintenance instructions which, in turn, may be aggravated by inadequate patient-practitioner communication. The purpose of this research was to determine CL use, compliance and patient-practitioner communication during a 3-month long COVID-19 lockdown in

Purpose To determine the age and sex-standardized prevalence and risk factors of anterior blepharitis in a geriatric population in "…". Methods This population-based study was conducted on the elderly population (over 60 years of age) of Tehran, the capital of "…" in 2019. Examinations included visual acuity assessment, refraction, and complete slit lamp examination. After the diagnosis of anterior

Introduction The use of contact lenses (CL) is often associated with hallmark symptoms of dry eye disease (DED) such as red eye and dryness. Even though lipid-based artificial tears are already marketed for DED, there is little evidence that supports their use while wearing soft CL. Methods An oil in water (O/W) nanoemulsion was formulated with a highly-stable oily phase composed of castor oil and

Objectives To evaluate compliance with orthokeratology (Ortho-K) care and its influencing factors among parents of 6–13-year-old myopic children in Taiwan. Methods Parents who are responsible for the care of the Ortho-K lenses of their myopic children were recruited through a closed Facebook peer support group to answer an online compliance questionnaire, including the wear and care behaviours and

Background A range of myopia management (MM) contact lenses are becoming available to practitioners. These lenses are designed to slow myopia progression and axial elongation. This study explored the initial experience of participants wearing daily disposable MM contact lenses to investigate established factors previously associated with successful lens wear. Methods This was a prospective, double-masked

Purpose To investigate conjunctival vascular density (VD) using Anterior Segment Optical Coherence Tomography Angiography (OCTA) in Scleral Contact Lens (ScCL) wearers. Methods In this cross-sectional study, the conjunctival blood VD was assessed using OCTA with an anterior segment lens adapter. The nasal surface of each eye (6 ×6 mm) was scanned to a depth of 800 μm with ScCL and fifteen minutes after

Purpose Investigate changes in optical properties of contact lenses materials (transmittance and reflectance) and lens care solutions (absorption and fluorescence) resulting from its interaction. Methods From an experimental study, triplicate measurements of transmittance and reflectance of five contact lenses (Senofilcon A, Lotrafilcon B, Balafilcon A, Comfilcon A, and Omafilcon A), as well as UV-vis

Purpose To report on the ocular health and safety of children fit with soft hydrogel daily-disposable contact lenses, and followed for 6-years in a double-masked clinical trial investigating the performance of a dual-focus contact lens designed to control myopia progression. Methods Children aged 8−12 years, naïve to contact lens wear, were enrolled across four international sites. During years 1–3

Purpose To compare lens cleaning routines using a povidone iodine-based rigid lens disinfecting solution and its effect on conjunctival colonisation, and lens and lens case contamination. Methods Participants, aged 6–10 years, receiving orthokeratology treatment were randomised to four lens cleaning routines: with and without the use of daily and/or weekly cleaners, which were performed by their parents

Purpose To assess the level of compliance related to contact lens (CL) wear in university students in Spain. Methods A web-based questionnaire was distributed to university students through their representatives to assess general demographic information, questions related to CL history, level of compliance with CL care and CL-related complications. Results A total of 266 participants with an average

Purpose To examine the association between modifiable lifestyle factors and dry eye disease. Methods Three hundred and twenty-two community residents (186 females, 136 males; mean ± SD age, 41 ± 22 years) with no major systemic or ophthalmic conditions (other than dry eye disease) were recruited in a cross-sectional study. A lifestyle factor questionnaire was administered, and dry eye symptomology

Purpose During the COVID-19 pandemic, the widespread use of face masks was recommended as a key measure against the spread of SARS-CoV-2. A marked increase in dry eye symptoms among regular mask users was reported, but the prevalence of this condition has not been described in the literature yet. The aim of this observational, descriptive, and cross-sectional study was to measure self-reported symptoms

Scleral lenses can affect a range of anterior segment structures including the eyelids and the tears. The eyelids, consisting of the outer skin layer, the middle tarsal plate, and the posterior palpebral conjunctiva, provide physical protection and house the meibomian glands and cilia which have important and unique functions. Tears consist of a mix of aqueous, mucus, and lipidomic components that

Purpose This study sought to estimate the prevalence and associated risk factors of symptomatic dry eye in the general non-clinical Ghanaian population. Methods This was a cross-sectional population-based study conducted from November 2019 to February 2020. A stratified, multistage, random sampling technique was used to select participants aged 18 years and above from the capital cities of eight administrative

Purpose This study evaluates the spectral transmission of photochromic contact lenses. Method A custom built photochromic filter transmission testing device (ICS photochromic bench) was developed to measure the spectral transmission of light adaptive filters. The spectral properties of seven contact lenses were measured using the ICS photochromic bench at 23⁰C and 35⁰C in their exposed (darkening)

Aim COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several reports have provided conflicting recommendations regarding contact lenses (CL) use during COVID-19, causing confusion among CL wearers. The aim of this study is to assess CL wearers’ attitudes toward CL wear and care during COVID-19 pandemic. Methods A web-based cross-sectional online survey was used to

Purpose To report on a second-generation prototype contact lens (modified lens) with enhanced optics to correct coma aberration and compare its performance with that of the prototype contact lens (conventional lens) used to optimise correction of coma aberration in keratoconus (KC). Methods Both lenses were designed as a set of standardised soft contact lenses (SCLs) with asymmetric powers along the

Purpose While knowledge of the ocular surface sagittal height (OC-SAG) is increasing with newer instrumentation, understanding of soft lens sag values (CL-SAG) in daily clinical practice is limited. This study aimed to report the differences in CL-SAG of a large collection of daily disposable (DD), reusable (2-week and 4-week replacement) and toric lens designs. Methods 12 different spherical DD and

Purpose This study aimed to evaluate the structural changes in meibomian glands (MGs) and meibomian gland dysfunction (MGD)-associated ocular surface alterations in contact lens (CL) wearers. Methods This prospective, multi-center, cross-sectional study included 44 soft CL wearers, 21 rigid CL wearers, and 26 healthy non-wearers. After completing the Ocular Surface Disease Index (OSDI) questionnaire

Pseudomonas aeruginosa and Staphylococcus aureus are the two dominant Gram-negative and -positive species, respectively, isolated from patients with contact lens-related bacterial keratitis. The clinical features of bacterial keratitis vary, such that timely differential diagnosis can be challenging, which may cause a delay in diagnosis resulting in poorer outcome. This review aims to explore the current

Purpose To test the Contact Lens Assessment in Youth Contact Lens Risk Survey (CLRS) scoring algorithm in soft contact lens (SCL) wearers presenting with SCL-related adverse events and healthy matched controls. Methods This prospective case-control study compared CLRS responses in SCL wearers presenting with symptomatic red eyes (Cases) with age-, sex- and site-matched healthy SCL wearers (Controls)

Purpose To determine factors associated with non-adherence to contact lens wear schedule involving single vision and myopia control contact lenses in children. Methods Data from 379 children enrolled in a prospective, double masked, randomized clinical trial, aged 8–13 years, cycloplegic spherical equivalent of -0.75 to -3.50D and wearing either: single vision silicone hydrogel (SiH) CL (control lens);

Purpose To report three cases of acute corneal edema occurring decades after penetrating keratoplasty (PK) for keratoconus in eyes wearing scleral contact lenses (ScCLs) with previously clear corneal grafts. Methods Retrospective chart review of three ScCL wearers presenting for sudden onset pain and blurred vision. Data extracted included clinical presentation, year and reason for PK, ocular medications

Purpose To determine how Meibomian gland (MG) morphology affects MG function by means of gland expression with the effect of treatment. Methods Fifteen patients (aged 31.6 ± 13.1 years) from a dry eye clinic diagnosed with MG dysfunction had their 365 lower lid MGs visualised with a slit-lamp biomicroscopy. Using infrared meibography (Oculus K5m), MG length, width and tortuosity were objectively measured

Objective To determine the short-term effect of contact lens (CL) wear on the self-concept of adolescents. Methods In this open-label trial, first-time CL wearing adolescents were prescribed Delefilcon A (DAILIES TOTAL1,® Alcon, USA) daily disposable CL. To determine the self-concept level of the subjects at dispensing and after one month, the Turkish adapted version of the Piers-Harris Children’s

Background The purpose of this review was to evaluate the consistency of central corneal thickness (CCT) values reported with use of Topcon SP-2000 P and SP-3000 P non-contact specular microscopes since their introduction in 1999 with the two microscopes having been commonly used in a wide range of studies. Methods As a primary resource, PubMed was used to search for peer-reviewed articles in any language

Purpose To understand the safety of treating contact lens (CL) discomfort with a new artificial tear when it is directly applied to a CL-wearing eye. Methods This was a two-week, two-visit, double-masked study that randomized participants with CL discomfort to use Systane Complete (artificial tear), Sensitive Eyes (rewetting drop), or no treatment. Drops were applied before, twice during, and after

Purpose This work set out to investigate if there was an association between subjective comfort and both subjective and measured vision during the use of contemporary daily disposable soft toric contact lenses. Methods Thirty-eight habitual soft contact lens wearers wore each of three daily disposable toric lenses for one week in a prospective, crossover, randomised, single-masked study. The following

Purpose To investigate the relationship between the real contact lens imprint into the conjunctival tissue, observed by optical coherence tomography (OCT) and conjunctival staining and contact lens wearing comfort. Methods 17 participants (mean age = 26.6 SD ± 3.6 years; 7 females) were fitted with three different contact lenses base curves of the same silicone hydrogel custom lens type (Visell 50;

Purpose To describe the development and report psychometric properties of the Contact Lens Risk Survey (CLRS) to identify patients at risk for soft contact lens-related complications. Methods Psychometric properties of the CLRS, a web-based survey with branching logic, were determined using data from 5 multi-site fieldings (n = 1059), including re-fielding to sub groups. Responses from participants

Purpose To evaluate the intrasession repeatability of corneal, limbal and scleral measurements obtained by an experienced operator with a Fourier transform profilometer in healthy eyes. Methods Prospective, single-center study including 35 eyes of 35 participants with ages ranging from 13 to 52 years. All patients underwent three consecutive corneoscleral topographic evaluations with the Eye Surface

Purpose To evaluate visual function, ocular surface integrity and dry eye symptoms with an extended depth-of-focus (EDOF) design and a conventional multifocal (MF) contact lens (CL) after 15 days of wear. Methods A crossover single mask randomised clinical trial was conducted including 30 presbyopes who used an EDOF and a conventional MF CL (Biofinity MF) for 15 days each. Defocus curves, depth-of-focus

Objective To describe outcomes using impression based-scleral devices for the management of anterior segment disease. Methods Retrospective chart review identified all patients who were fitted with impression-based scleral devices between January 1, 2013 and June 30, 2019 at three specialty contact lens practices. Patient demographic data, indication for device use, visual and physiological outcomes

Aim To establish contact lens wear and care practices during the COVID-19 pandemic in Spain. Method A 58-item anonymous online survey was distributed during the period 30th April to 10th May via Qualtrics. The survey explored: a) demographic characteristics (age, sex, general health and where they were living during lockdown), b) changes in their contact lens use during lockdown, c) hygiene and contact

Purpose The physical properties of contact lens care solutions and Eye Drops (ED) may affect initial comfort and dry eye symptomatology in contact lens wearers, although these properties are not always provided by manufacturers. The present study aimed to measure and compare the osmolality and pH of commercially available contact lens care solutions and ED. Methods Forty-four solutions were tested

Aim To compare the in-vitro videokeratoscopic surface dewetting properties of new-generation silicone hydrogel (SiH) planned replacement contact lenses (CL) with those of daily disposable CLs. Method A chrome coated cornea model was used for the in-vitro evaluation of surface dewetting. Pre-lens and post-lens film layers were formed by instilling a normal preservative-free normal saline solution (PFNs)

Purpose To investigate the repeatability of waveform signal parameters, measured with the Ocular Response Analyzer (ORA), in children. Methods Two sets of ORA measurements, with a 10-min break between them, were performed on children, aged six to <11 years old, either wearing single-vision spectacles (SVS) or orthokeratology (ortho-k) lenses. Intraclass correlation coefficients (ICCs) were used to

A large fluctuation in intraocular pressure (IOP) and a high peak IOP remain the risk factors for progressive visual field loss in patients with glaucoma, which is a leading cause of irreversible blindness. However, IOP measurements during working time cannot provide sufficient information on IOP to guide clinicians in setting IOP target values. Contact lenses are extensively used in ophthalmology

Objective This case report aims to highlight the corneal deformation induced by soft contact lens (SCL) wear, which is accompanied by changes in not only the anterior but also the posterior surface of cornea. Case Report Cases are presented of two patients who wore non- planned replacement SCL for more than 15 years fabricated from materials with low oxygen permeability, sought a consultation with

Purpose To study the effect of daily disposable contact lens (DDCL) refitting in monthly contact lens (CL) wearers suffering from contact lens discomfort (CLD), and to assess if there is a placebo effect associated with this CLD intervention. Methods Symptomatic CL wearers, according to the Contact Lens Dry Eye Questionnaire 8 (CLDEQ-8 ≥ 12 points), were divided into two groups. The study group was

Purpose To determine the proportion of contact lens neophytes that can be successfully fitted with a photochromic contact lens, and to survey subjective performance outcomes compared to habitual spectacles. It was hypothesized that at least 50 % of lens fits would be successful. Methods Eleven sites enrolled contact lens neophytes with up-to-date spectacles. Subjects were fitted bilaterally with a

Purpose To summarize the peer-reviewed literature on corneal structural changes after orthokeratology (OK) and to analyze the quality of the studies published. Methods An exhaustive search was carried out in the databases Pubmed MEDLINE, Web of Science and Scopus. Original studies in English, with a cohort or experimental design and analyzing the cellular and structural changes of the cornea after

Significance This study set out to illustrate the trajectories of myopia control in time sequence and explore orthokeratology compliance for parents with myopic children in the first fitting within one year. Profiling these results is crucial to improving myopia control and orthokeratology care. Purpose To obtain a better understanding of myopia control and orthokeratology care that could promote compliance

Purpose To investigate the incidence and peak elevation of conjunctival prolapse during short-term open eye scleral lens wear and its association with lens fitting characteristics. Methods Ten young, healthy adults (mean age ± SD, 30 ± 4 years) wore a high Dk sealed scleral lens for 90 min with an initial central post-lens fluid reservoir thickness defined as low (144 ± 23 μm), medium (487 ± 63 μm)

Objectives To describe current components of scleral lens curricula at U.S. based optometry colleges and universities. Methods Contact lens educators were surveyed between June 2019 and August 2019 regarding their optometric scleral lens curriculum. Respondents were asked to describe their experience and involvement in optometric scleral lens education as well as to describe components of scleral lens

Purpose To evaluate the combined effect of intense pulsed light (IPL) therapy and meibomian gland expression on extracellular matrix metalloproteinase-9 (MMP-9) levels and clinical outcomes of moderate and severe meibomian gland dysfunction (MGD) treatment. Methods This retrospective study was conducted on 45 eyes of 23 patients with moderate and severe MGD. Each eye underwent three IPL sessions and

Purpose To assess the correlation of the scleral shape and corneal tomographic parameters in keratoconus. Methods Twenty eyes of 15 keratoconus patients with no previous specialty lens wear or ocular surgery were included in this study. Corneal imaging was obtained with the Pentacam HR and three-dimensional (3D) corneoscleral maps were acquired using the Eye Surface Profiler, ESP. Sagittal height was

Purpose Previous reports indicate that “eye fatigue” occurs in roughly 60 % of the adult population using digital devices and may negatively impact quality of life. However, the construct of eye fatigue remains poorly understood. The goal of this study was to quantify the relationship among symptoms most frequently associated with eye fatigue in those using digital devices. Methods Six hundred and

Purpose To evaluate the comparability, discriminative ability, and optimal thresholds for non-invasive tear film breakup time measurements obtained from the Oculus Keratograph 5M and Medmont E300 in detecting other signs and symptoms of dry eye disease, as defined by the TFOS DEWS II diagnostic criteria. Methods One hundred and thirty-four participants (53 male, 81 female), with a mean ± SD age of

Objective To evaluate the safety of overnight orthokeratology (OK) wear and explore whether factors such as age, refraction and allergic conjunctivitis (AC) history were associated with corneal adverse events (AEs) incidence. Methods Medical records of consecutive patients who started OK for myopia correction and continued for more than one year were retrospectively reviewed. Clinical data including

Purpose To determine whether the adaption of neophytes to rigid gas permeable lenses (GPs) could be accelerated by changing their diameter or surface lubricity. Methods This was a 2 part prospective double-masked randomised wear study. An GP lens (Roflufocon D material, 9.6 mm diameter) with and without a Hydrapeg plasma coating surface was worn by 119 neophytes (21.1 ± 3.5 years; 77% female) on separate

Purpose To determine the relative contributions to perceived discomfort during contact lens wear of contact time with the lens and the time of day at which wear begins, using a wearing framework similar to that of regular users. Methods Twenty-three participants reported ocular discomfort using a 1–100 visual analogue rating scale, when prompted by email, during one day without contact lenses and on

Purpose Myopia prevalence has increased in recent years, including the levels of high myopia. While myopia has been associated with scleral remodelling and changes in posterior scleral shape, there has been little research examining how myopia affects in-vivo anterior sclera shape. We compared anterior scleral shape in emmetropes, low to moderate myopes, and high myopes. Methods In this prospective

Purpose To examine the relationship between central post-lens fluid reservoir thickness and central corneal oedema during short-term closed eye scleral lens wear, and to compare these empirical oedema measurements with open eye lens wear data and current theoretical modelling for overnight scleral lens wear. Methods Ten participants (mean ± standard error 30 ± 1 years) with normal corneas wore scleral

Purpose This study examined the rate and level of microbial contamination of silver and non-silver (control) barrel contact lens storage cases in vivo. Methods A prospective, single-centre, randomized, double blinded, crossover study was conducted to evaluate the efficacy of silver and control barrel cases used with an Oxipol™-based disinfecting solution over a two-month period. Lens cases were collected

Aim Contact lens wearers need to maintain optimal hygiene practices during the COVID-19 pandemic to minimise contact-lens complications including microbial keratitis and corneal infiltrative events. This online survey (UK and Ireland) explored contact lens wearers’ compliance behaviours, attitudes and concerns during the pandemic. Method The 60-item anonymous online survey was distributed during a

Purpose To investigate antibiotic eye drops prescribing patterns of contact lens practitioners in Mainland China for orthokeratology (ortho-k) patients and to develop guidelines for their use. Methods A questionnaire on their antibiotic prescribing habits was administered to eye care practitioners (ECP) involved in ortho-k lens fitting nationwide via an official online account. Multiple logistic regression

Purpose To evaluate the bacterial spectrum and antimicrobial susceptibilities of pathogens isolated from contact lens-related bacterial keratitis cases in a large academic Greek hospital. Methods All adult patients with positive corneal scrapings or contact lens culture between 2007 and 2016 at the University Hospital of Heraklion, Greece, were retrospectively identified through a local microbiology

Objective To investigate differences in SNPs in TLR genes between people who had keratitis and controls in an Indian population. Methods 145 cases of keratitis and 189 matched controls were recruited. DNA was extracted from peripheral blood. Single nucleotide polymorphisms (SNP) in TLR2 (n = 6), TLR4 (n = 15), TLR5 (n = 13) and TLR9 (n = 10) were analysed. The risk of developing keratitis was assessed

Purpose To investigate the behaviour of contact lens (CL) wearers in Spain during the COVID-19 pandemic. Methods An anonymized web-based questionnaire was used to assess demographics, CL history, and activity, CL wear habits and perceived risk of infection due to CL wear during the COVID-19 pandemic. Results A total of 737 participants with an average age of 27.4 (±9.3) years completed the online questionnaire