This study examined the formulation of Microalgal Chloroform Extracts (MEs) and Silver nanoparticles (AgNPs) co-application for anticancer activity against MCF-7 and 4T1 cells, without affecting the non-cancerous Vero cell-lines. The concentration, ratios and duration of treatments were optimized, and the flow cytometric and cell cycle analyses were carried out. The metabolites based on Gas Chromatography-Mass

The p-quantile residual life function summarizes the lifetime data in a useful and simple concept and in units of time. For uncensored data or when the upper tail of the observations is not censored, this function can be estimated by applying the well-known Kaplan-Meier survival estimator. But, when research terminates in heavy right-censored lifetime data which is the case of many biomedical and survival

The current study was concentrated to detection of anti-cancer compound from marine Streptomyces akiyoshiensis GRG 6 (KY457710) against MCF-7 breast cancer cells. The partial purification of TLC was moved three different active spots. Among the spots, the third spot of the extract was shown excellent anti-cancer properties against MCF-7 human breast cancer cells. The available anti-cancer compounds

Tripogon loliiformis, an Australian native resurrection grass having an abundant gene pool for combating desiccation, can be the putative model system for functional characterization of stress tolerance genes due to its diploid genome and being a monocotyledonous plant and member of the grass family (Poaceae), like many important cereal crops. For developing callus mediated regeneration from mature

Background As dominant components of planktonic microeukaryotes, the tintinnine ciliates act as a trophic link between microbial food web and traditional planktonic food chain in aquatic ecosystems. However, traditionally the taxonomy and systematics of tintinnines have been based on the lorica. It is now accepted that lorica features alone are insufficient and that cytological and molecular information

The Red Sea coast is rich in different types of seaweeds, which are suggested to possess medicinal properties. In this study, methanolic extract of Chondrus Crispus (MEC), a species of red algae collected from the southeast coast of Jeddah, Saudi Arabia was prepared and analysed for its chemical composition, antioxidant, anti-inflammatory and cytotoxic properties. HPLC analysis revealed that flavonoids

In this study, the anti-oxidant and anti-bacterial activity of marine brown algae Turbinaria ornata (T. ornate) extract was purified by soxhlet apparatus method. The invitro studies of total anti-oxidant activity and DPPH hydroxyl scavenging activity assays were suggested that the T. ornata extract has more anti-oxidant activity. Agar well diffusion and minimum inhibition concentration results were

The substituted-9-bromo-9,10-dihydro-9,10-ethanoanthracenes ortho 8a-12a and meta 8b-13b have been synthesized via Diels-Alder reaction under microwave conditions. The cycloadduct isomers ortho 8a-11a and meta 8b-11b, with priority to ortho 8a-11a, were obtained from the reaction of 9-bromoanthracene 1 with acrylonitrile 2, 2-chloroacrylonitrile 3, methacryloyl chloride 4 and acrylic acid 5, while

Development of Intensity-Duration-Frequency (IDF) Curves is important for the design of various hydraulic structures such as culverts, dams, and stormwater drainage systems. In this paper, rainfall analyses are conducted to evaluate the effect of using rainfall records from different rain gauge types on IDF Curves construction. Rainfall data are collected from two recording rain gauges at Namman catchments

Objectives Current study illustrates the impact assessment of TiO2 nano-particle seed priming on the overall germination, physiology in maize thriving under salinity stress. Methodology Seeds of maize cultivar were soaked in 40, 60 and 80 ppm aerated solution of TiO2nano-particle for one day and nano-primed seeds were then exposed to salinity stress, i.e., 200 mM NaCl on paper culture system. Results

Tamarix is an important genus of Tamarieaceae family, known for its medicinal importance. Its taxonomy is tricky, and a few molecular makers are available for species identification. The present study was designed to evaluate the genetic diversity among 21 Tamarix specimens collected from Thal desert, Punjab, Pakistan. Ten Inter-Simple Sequence Repeats (ISSR) and six Simple Sequence Repeats (SSR) markers

Objectives The toxicity of cadmium in various animal models, in particular the liver, has been studied. The objective of this research was to determine the antioxidant and the hepatoprotective role of Pleurotus ostreatus (PE) extract in Cadmium-intoxicated rats. Methods: Rats of the first group were used as control animals while rats of the second group were administered PE for 5 days. Animals of the

The present paper studies the novel generalized (G′/G)-expansion technique to two nonlinear evolution equations: The (2+1)-dimensional Konopelchenko-Dubrovsky (KD) equation and the (2+1)-dimensional Kadomtsev-Petviashvili (KP) equation and acquires some new exact answers. The secured answers include a particular variety of solitary wave solutions, such as periodic, compaction, cuspon, kink, soliton

Objectives A.baumannii is considered as a “red alert” nosocomial human pathogen and exhibits an extensive antibiotic resistance spectrum. The biofilm formation mediated by the csgA is a potent virulence factor in A.baumannii and targeting the same would be of a novel strategy to control A.baumannii infections. The aim of the present study is thus to evaluate the anti-biofilm activity of essential bio-compounds

Objective In the present work, the potential use of raw date stone as an inexpensive carbonized adsorbent material for removal of Pb(II) has been demonstrated. Methods The adsorption of Pb(II) ions onto carbonized date stone has been studied by batch adsorption method. The variables (pH, adsorbent dose and initial concentration of Pb(II) ions) of the adsorption process were optimized by response surface

In this paper, we analytically investigate axi-symmetric flow of a micro-polar fluid induced by peristaltic waves with progressively dilating amplitude. By means of mathematical formulation we examine its impact on swallowing of single food bolus through oesophagus. Liquid crystals, blood, some edible solutions resemble micro-polar property. Engineering applications using polymer solutions, colloidal

The calibration technique is the process of adjusting weights for the better enhancement of the estimate of the population parameters using auxiliary information. In this manuscript, we have proposed ratio and regression type calibration estimators for the population mean under both correlated and uncorrelated measurement errors. The variances of the proposed calibrated estimators to the first order

This study is the construction of the Green’s function and Sinc function for a class of nonhomogeneous singular boundary value problems (SBVPs). The equivalent Volterra-Fredholm integral equations can be derived from SBVPs by applying Green’s function. This can be approximated by Sinc-Collocation method. Convergence analysis is given. Our approach applied on three various examples. Errors in the solution

Objectives In this study, the crystalline phase, microstructure, chemical composition, and morphology of the powder of volcanic ashes from three different places have been investigated. Methods The raw materials were initially milled and the particle size was decreased to approximately 74 µm. X-ray diffraction (XRD), chemical analysis (XRF and ICP-OES technique), Fourier transform infrared spectroscopy

Fungi are heterotrophic organisms possessing cryptic lifestyles and have an individual hierarchy in the evolution of microorganisms on earth. Out of which, Keratinophilic fungi are allied molds that produce keratinase enzymes and diminish the keratin matters in or on the soil. Fifty soil samples were collected from various sites of Jaipur district, India to analyze incidence of keratinophilic fungi

Studies on genetics and trait relationships with grain yield and other agronomic traits are critical for improving the micronutrients content in the grain and it forms an effective strategy for breeding bio fortified sorghum. It greatly contributes to addressing micronutrient malnutrition in poor people who are dependent on sorghum as a staple food. Development of hybrids with high grain Fe and Zn

Background SA (Salicylic acid) and JA (Jasmonic acid)/ET (Ethylene) are the defense and growth hormone regulators involved in alleviating the biotic and abiotic stresses. WRKY and NAC genes are contributors to plant resistance due to their active role in SA and JA/ET defense mechanism. Methods WRKY and NAC transcription factors (ptHR293 and ptHR759, respectively) were serially selected (by performing

Cyprinion acinaces are ray-finned fish belongs to genus Cyprinion. Previous studies have reported that this species has two subspecies, Cyprinion acinaces acinaces, and, Cyprinion acinaes hijazi, however, the validity of later was always in doubt. In past, this fishes were classified merely based on morphological characteristics, and modern biotechnology related tools were never used, which would had

A sequence of approximating operators is constructed in the present article with the help of Boas-Buck-type polynomials (BB-polynomials). We called this constructed operator as Jakimovski-Leviatan-Păltănea operators (JLP-operators) involving BB-polynomials. We establish some approximation properties of approximating operators converging towards the function to be approximated. We investigate versatile

The available literature on the safety profile of tamoxifen in human patients and in experimental animals is mostly contradictory. The present study was therefore, designed to understand the safety profile of tamoxifen using Swiss albino mice. Swiss albino mice of age 13 weeks were orally administered tamoxifen (35 mg/kg/day) for 80 days. The breast, liver, and ovaries were used to evaluate the toxicity

The preparation of Co-doped magnetite ferrofluids from natural sand was developed using a double-layer technique. The Co-doped magnetite nanoparticles formed a spinel phase with lattice parameters in the range of 8.355–8.422 Å and tended to agglomerate with the particle sizes of 7–12 nm. The presence of the first and second layers from oleic acid and DMSO was detected by the infrared spectrum as well

Magnetic nanowires are of technological importance as their magnetic properties can be controlled by their dimensions and shape. In soft magnetic nanowires (e.g. Ni 80 Fe 20 alloy or Permalloy), shape anisotropy has a very strong effect on their magnetic properties and thus the wire width and thickness control the domain patterns, nature of magnetization reversal, and the switching field. The switching

The present study assessed the ameliorative potential of a commercial probiotic, Protexin® and its nanoformulation against cadmium (Cd) toxicity in Wistar rats. The ‘green’ synthesized nanoparticles had a size of 170 nm (PDI 0.527) with spherical and tubular bacillary shapes. Rats were exposed to 70 ppm of cadmium chloride hydrate for 35 days. Group I and V were negative and positive control respectively

The multiple metal resistant Staphylococcus sp. strain AS6, isolated from wastewater of Pakistan, was able to resist 25 mM arsenite and 150 mM arsenate. SEM analysis showed that no significant change in bacterial morphology under arsenite exposure was observed while EDX and FTIR analyses confirmed the surface adsorption and uptake of arsenite into the bacterial cells exposed to 15 mM arsenite. The

An efficient, eco-friendly and sustainable approach for the synthesis of novel spiroindeno[1,2-b]quinoxaline-3-phenylspiro[4,3″]benzylidenepiperidone ring system has been developed by a one-pot four component [3 + 2] cycloaddition strategy. The 1,3-dipole generated in situ from quinoxalinone and l-phenylalanine reacts with the highly functionalized dipolarophiles, bisarylidene piperidones affording

Metals are major toxic elements and cause various diseases and damage shorebirds. The study envisaged the heavy metals content in the feathers of shorebirds, prey, water, and sediment from Pichavaram Mangrove Forest (PMF). Primary feathers of shorebirds species such as Curlew Sandpiper, Eurasian Curlew, and Painted Stork were collected and analyzed the following metals viz., Cd, Cu, Cr, Co, Pb, Hg

Carbon tetrachloride (CCl4) is a Potential nephrotoxin that causes severe and prolonged chemical toxicity. Investigations have been accomplished on numerous species of genus Artemisia, but the plant Artemisia brevifolia has hardly been used in this respect. The present study was considered to ascertain the effects of “Artemisia brevifolia plant extract” against CCl4 prompted nephrotoxicity in male

Objectives The current study is to estimate the bisoprolol (BOP) oral treatment of rats against the myocardial infarction (MI) administrated by using isoproterenol (ISO). Methods Treatment of rats are MI administration by subcutaneous for two successive days of ISO (85 mg/kg). The tissue of heart is removed without delay, it is washed used isotonic chilled saline in this study. Plasma is separated

Mitochondrion is an organelle responding to providing cell energy by oxidative phosphorylation (OXPHOS) reaction. In the mitochondrial genome of animals, 13 important protein-coding genes (ND1, ND2, ND3, ND4, ND4L, ND5, ND6, CTYB, COX1, COX2, COX3 ATP6, ATP8) play important roles on mediating the OXPHOS reaction. The study is to compare the expressional level of 13 mitochondrial PCGs among muscle of

Background Saprolegniasis often cause a significant economic losses to fish hatchery and intensive fish industry. The treatment of saprolegnoid diseases with malachite green seems to have harmful effect and is considered as a mutagenic and carcinogenic substance. The teratogenic and carcinogenic potential of malachite green increased the necessity to find an effective alternative treatment to control

Isoproturon (IP), a systemic herbicide, is also considered as a potential groundwater contaminant. In the present study, the radiation-induced degradation of IP employing gamma-rays is investigated. Several factors such as radiation dose, pH and the presence of co-contaminants such as H2O2, isopropanol, tert-butanol, coffee waste (CW), carbonized coffee waste (CWC) and TiO2, which might affect the

This study focused on comparing between dipteran fauna recovered from small mice (Mus musculus Linnaeus, 1758) and albino rat (Rattus norvegicus Berkenhout, 1769) carcasses placed in different habitats (a botanical garden and on a over the roof of 3rd floor of the faculty of science‘s building in the university campus). It was conducted during winter 2018 in Al-Dir'iya, Riyadh, Saudi Arabia. Collected

Objectives: The purpose of this paper is to provide global and national climate policy makers with smooth patterns of carbon dioxide (CO2) emissions that better fit prescribed climate targets, in comparison with existing mitigation models. Methods: Based on an accessible mathematical analysis, a linearly-increasing relative rate of reduction is considered for the emissions, and therefore, Gaussian

Undoped and palladium-doped perovskite bismuth ferrite nitrogen dioxide (NO2) gas sensors (BiFeO3 i.e. BFO and Pd-BiFeO3 i.e. Pd-BFO) are successfully synthesized via an easy and low-cost sol–gel process. The Pd-doping in BFO is confirmed through an X-ray diffraction data, field emission scanning electron microscopy images, energy-dispersive X-ray spectroscopy analysis, and its influence on the structure

Our study demonstrated the biological changes produced in the Rhabdomyosarcoma (RD) cell line triggered by the photochemical reaction between PHOTOGEM® (photosensitizing agent) and He-Ne laser light (wavelength = 632.8 nm of red light). The basic parameters of photodynamic therapy were optimized to study photosensitizer localization/uptake, PHOTOGEM® absorption spectra, cytotoxic effects, phototoxic

Objective History of the utilization of various parts of Camellia sinensis such as seed oil in different folklore medicaments and plants leaves for preparing green tea is very old. Pharmacokinetics (PK) plays a key role in the drug discovery stage by channelizing the medicinal chemist in the optimization process of chemical sequences and lends a hand to pharmacologists to invent in vivo studies. The

The increasing drug resistance pattern in bacterial pathogens promotes the need to find out alternative strategies to ensure human health. In the imperative lookout for effective drugs to combat multidrug-resistant bacteria, silver nanoparticles (AgNPs) are given priorities. Hence in the present approach, AgNPs were synthesized using the extract of the inflorescence of a medicinal plant, and its antibacterial

Objectives The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, also known as COVID-19 pandemic has caused an alarming situation worldwide. Since the first detection, in December 2019, there have been no effective drug therapy options for treating the SARS-CoV-2 pandemic. However, healthcare professionals are using chloroquine, hydroxychloroquine, remdesivir, convalescent plasma

The Chilean Patagonian lakes are characterized by their marked oligotrophic or oligomesotrophic status and low zooplankton species abundances, many of these lakes with oligomesotrophic status is associated to human intervention due towns in their shores. The aim of the present study was determine the relations between spectral properties (LANDSAT/OLI), chlorophyll and plankton abundances in two north

Objectives The main aim of this study is to isolate and characterize fibrinolytic enzyme from Bacillus flexus. Methods Fish meal of Sardinella longiceps and anchovy was optimized using a two-level full factorial design (25) and response surface methodology. The significant physical factors and nutrient sources (peptone, maltose, and magnesium chloride) were identified by statistical approach. The properties

The M. citrifolia, commonly called starvation fruit, plays an essential role in daily dietary intakes, as it contains several vitamins, phytochemicals, and electrolytes. These constituents have several biological activities that are anti-tumor, antibacterial, antiviral, antifungal, and play a role in the immune system. The silver nanoparticles (AgNPs) were synthesized using a more uncomplicated and

Seawater intrusion of the northwestern Saudi Arabia, has been investigated through integrated geophysical techniques of electrical resistivity tomography (ERT), seismic refraction tomography (SRT), and time-domain electromagnetic (TDEM). These geophysical measurements were conducted along three parallel NW-SE profiles. Then, processed and interpreted with geotechnical data of four boreholes drilled

A new exact solution is obtained for the Oberbeck–Boussinesq equations describing the steady-state layered (shear) Marangoni convection of a binary viscous incompressible fluid with the Soret effect. When layered (shear) flows are considered, the Oberbeck-Boussinesq system is overdetermined. For it to be solvable, a class of exact solutions is constructed, which allows one to satisfy identically the

An investigation of physicochemical properties of Nigella sativa seed oil from Al-Qassim, KSA was conducted using cold press and Soxhlet extraction methods. The effect of solvent polarity on the oil components and properties were examined using hexane, tetrahydrofuran, ethanol, dichloromethane, methanol and methanol-water binary system. The results demonstrated a high yield of oil with the Soxhlet

Study conducted to evaluate the impact of dietary incorporation of chitosan nanoparticles (CsNPs) bio-synthesis and Spirulina platensis on the growth performance and body .composition of intensive cultured fingerling of black tiger shrimp (Penaeus monodon) in addition to the effect of the diets on heavy metals concentrations in water of culture cages. Six diets were prepared to contain approximately

Liquid fresh water is scarce in arid and semi-arid regions. Some organisms in these stressful habitats are well adapted to the environmental conditions and obtain fresh water directly from the atmosphere. This ability of “moisture harvesting” relies on specific microstructural features organisms exhibit at their external surfaces. In this respect, the dew harvesting ability of the arid plant species