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High flexion femoral side remnant preservation positioning technique: a new method for positioning the femoral tunnel in anterior cruciate ligament reconstruction J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-18 Xiaobo Li, Jiajun Lu, JIxian Su, Hanlin Li, Xiaoying Liu, Ran Ding
The aim of this study is to find a new method for femoral side preservation positioning in anterior cruciate ligament (ACL) reconstruction and test the accuracy and precision of this method. Fifty patients with isolated ACL rupture (42 males and 8 females) who underwent single-bundle ACL reconstruction in our hospital between July 2022 and July 2023 were included. The lowest point of the cartilage
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Glaucocalyxin A delays the progression of OA by inhibiting NF-κB and MAPK signaling pathways J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-18 Xin Hong, Xuqiang Liu, Bo Li, Shoujie Shi, Kai Xiao, Tiantian Xu, Yaoyang Nie, Min Dai, Meisong Zhu
Osteoarthritis (OA) is a common degenerative joint condition marked by inflammation and cartilage breakdown. Currently, there is a dearth of treatment medications that can clearly slow the course of OA. Glaucocalyxin A (GLA) is a diterpene chemical identified and extracted from Rabdosia japonica with antithrombotic, anticoagulant, anti-tumor, anti-inflammatory, anti-oxidant, and other pharmacological
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The influence of anterior cervical discectomy and fusion surgery on cervical muscles and the correlation between related muscle changes and surgical efficacy J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-16 Chong Sun, Hongfei Xiang, Xiaolin Wu, Bohua Chen, Zhu Guo
Anterior cervical discectomy and fusion surgery (ACDF) is a common technique in treating degenerative cervical spondylosis. This study is to evaluate the changes of cervical muscles after ACDF and analyze the correlation between related muscle changes and clinical efficacy. Sixty-five postoperative patients (single-level ACDF) with cervical spondylotic myelopathy from January 2013 to December 2022
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A retrospective study: exploring preoperative hyponatremia in elderly patients with hip fractures J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-16 Li-Tao Shi, Zhen Feng, Cui-Min Zhu
This research aims to examine the frequency, age-related distribution, and intensity of preoperative hyponatremia among elderly individuals with hip fractures. This study aims to provide valuable insights into the diagnosis of preoperative hyponatremia in this patient population. This research involved the analysis of clinical data obtained from 419 elderly individuals with hip fractures (referred
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Navigation versus fluoroscopy in minimalinvasive iliosacral screw placement J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-16 Max Prost, Roman Taday, Carl Christoph Paul Beyersdorf, David Latz, Joachim Windolf, Max Joseph Scheyerer, Markus Rafael Konieczny
When needed operative treatment of sacral fractures is mostly performed with percutaneous iliosacral screw fixation. The advantage of navigation in insertion of pedicle screws already could be shown by former investigations. The aim of this investigation was now to analyze which influence iliosacral screw placement guided by navigation has on duration of surgery, radiation exposure and accuracy of
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Exosomes derived from umbilical cord-mesenchymal stem cells inhibit the NF-κB/MAPK signaling pathway and reduce the inflammatory response to promote recovery from spinal cord injury J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-16 Zhiwei Luan, Jingsong Liu, Mi Li, Yangyang Wang, Yansong Wang
Spinal cord injury (SCI) is a serious traumatic disease of the central nervous system and leads to incomplete or complete loss of the body’s autonomous motor and sensory functions, seriously endangering human health. Recently, exosomes have been proposed as important substances in cell-to-cell interactions. Mesenchymal stem cell (MSC)-derived exosomes exert good therapeutic effects and play a crucial
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m6A methylation modification and immune infiltration analysis in osteonecrosis of the femoral head J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-15 Weihua Fang, Peng Peng, Kun Lin, Fangjun Xiao, Wei He, Mincong He, Qiushi Wei
Osteonecrosis of the femoral head (ONFH) is a elaborate hip disease characterized by collapse of femoral head and osteoarthritis. RNA N6-methyladenosine (m6A) plays a crucial role in a lot of biological processes within eukaryotic cells. However, the role of m6A in the regulation of ONFH remains unclear. In this study, we identified the m6A regulators in ONFH and performed subtype classification. We
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Validity and reliability of the Modified Four Square Step Test in individuals with ankle sprain J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-15 Mehmet Yetiş, Hikmet Kocaman, Mehmet Canli, Halil Alkan, Hasan Yildirim, Nazim Tolgahan Yildiz, Şafak Kuzu
Postural instability and gait abnormalities are frequently observed after an ankle sprain. A modified Four Square Step Test (mFSST) was developed to assess dynamic balance during gait. The aim of this study was to evaluate the reliability and validity of the mFSST in individuals with ankle sprains. The study included 39 individuals with grade 1 and 2 ankle sprains with a mean age of 30.36 ± 6.21 years
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Duloxetine reduces opioid consumption and pain after total hip or knee arthroplasty: a meta-analysis of randomized controlled trials J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-13 Yicai Lin, Mingyang Jiang, Chun Liao, Qingjian Wu, Jinmin Zhao
There is no consensus in the current literature on the analgesic role of duloxetine after total hip arthroplasty (THA) or total knee arthroplasty (TKA). Thus, we designed this meta-analysis to reveal the analgesic effectiveness and safety of duloxetine in TKA or THA. As of October 2022, two authors (L.C. and W.Q.J.) independently searched five main databases (EMBASE, Web of Science, PubMed, Cochrane
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Time-elapsed microstructural imaging of failure of the reverse shoulder implant J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-12 Saulo Martelli, Egon Perilli, Xiaolong Fan, Sophie Rapagna, Ashish Gupta
Reverse Shoulder Arthroplasties (RSA) have become a primary choice for improving shoulder function and pain. However, the biomechanical failure mechanism of the humeral component is still unclear. The present study reports a novel protocol for microstructural imaging of the entire humerus implant under load before and after fracture. A humerus specimen was obtained from a 75-year-old male donor. An
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Geniposide alleviates cholesterol-induced endoplasmic reticulum stress and apoptosis in osteoblasts by mediating the GLP-1R/ABCA1 pathway J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-11 Mingliang Zhong, Zhenyu Wu, Zhixi Chen, Longhuo Wu, Jianguo Zhou
Cholesterol (CHO) is an essential component of the body. However, high CHO levels in the body can damage bone mass and promote osteoporosis. CHO accumulation can cause osteoblast apoptosis, which has a negative effect on bone formation. The pathogenesis of osteoporosis is a complicate process that includes oxidative stress, endoplasmic reticulum (ER) stress, and inflammation. Geniposide (GEN) is a
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Oxymatrine protects articular chondrocytes from IL-1β-induced damage through autophagy activation via AKT/mTOR signaling pathway inhibition J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-11 Jinying Lu, Jiang Bian, Yutong Wang, Yan Zhao, Xinmin Zhao, Gao Wang, Jing Yang
Osteoarthritis (OA) is a common degenerative joint disease characterized by persistent articular cartilage degeneration and synovitis. Oxymatrine (OMT) is a quinzolazine alkaloid extracted from the traditional Chinese medicine, matrine, and possesses anti-inflammatory properties that may help regulate the pathogenesis of OA; however, its mechanism has not been elucidated. This study aimed to investigate
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Efficacy and immune-inflammatory mechanism of acupuncture-related therapy in animal models of knee osteoarthritis: a preclinical systematic review and network meta-analysis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-08 Yingjie Huang, Hai Huang, Qiqi Chen, Yantong Luo, Jieni Feng, Yuexia Deng, Guangyao Li, Min Li, Jian Sun
Many KOA patients have not reached indications for surgery, thus we need to find effective non-surgical treatments. Acupuncture is thought to have the potential to modulate inflammation and cytokines in KOA through the immune system. However, the mechanisms have not been elucidated, and there is no network Meta-analysis of acupuncture on KOA animals. So we evaluate the effect and mechanism of acupuncture-related
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Application and evaluation of artificial intelligence 3D preoperative planning software in developmental dysplasia of the hip J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-08 Hongbin Xie, Jiafeng Yi, Yijian Huang, Renwen Guo, Yubo Liu, Xiangpeng Kong, Wei Chai
Accurate preoperative planning is crucial for successful total hip arthroplasty (THA) for developmental dysplasia of the hip (DDH). The aim of this study was to compare the accuracy of an artificial intelligence-assisted three-dimensional (3D) planning system (AIHIP) with two-dimensional templates in predicting acetabular cup size in THA for DDH. This study retrospectively analyzed image data from
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A biodegradable PVA coating constructed on the surface of the implant for preventing bacterial colonization and biofilm formation J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-08 Zhonghua Lei, Haifeng Liang, Wei Sun, Yan Chen, Zhi Huang, Bo Yu
Bone implant infections pose a critical challenge in orthopedic surgery, often leading to implant failure. The potential of implant coatings to deter infections by hindering biofilm formation is promising. However, a shortage of cost-effective, efficient, and clinically suitable coatings persists. Polyvinyl alcohol (PVA), a prevalent biomaterial, possesses inherent hydrophilicity, offering potential
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Obstetric-related lower back pain: the effect of number of pregnancy on development of chronic lower back pain, worsening of lumbar disc degeneration and alteration of lumbar sagittal balance J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-07 Erdal Güngör, Zeynep Karakuzu Güngör
This study aims to determine whether the number of pregnancies contributes to the development of chronic lower back pain, worsening the lumbar disc degeneration and altering the normal lumbar sagittal balance. There are 134 ladies participated in this study. They are divided into two groups based on their number of pregnancies (parity). All patients with chronic back pain were assessed using a visual
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Dyslipidemia may impact initial recovery following arthroscopic rotator cuff repair: a retrospective study J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-07 Lei Yao, Xiumei Zhao, Lu Mei, Yinghao Li, Long Pang, Chunsen Zhang, Jian Li, Xin Tang
The current literature shows that dyslipidemia can lead to a higher incidence of rotator cuff tears (RCTs) and an increased retear rate after repair. We aimed to evaluate the influence of preoperative dyslipidemia on postoperative pain, patient-reported outcomes (PROs), active range of motion (ROM), and structural integrity. A cohort of 111 patients who underwent arthroscopic RCT repair between January
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Comparison of outcomes after anterior cervical discectomy and fusion with and without a cervical collar: a systematic review and meta-analysis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-07 Tingxin Zhang, Gang Gao, Yanhong Li, Feng Gao, Wupeng Yang, Yongjiang Wang, Nana Guo
The clinical outcomes of patients who received a cervical collar after anterior cervical decompression and fusion were evaluated by comparison with those of patients who did not receive a cervical collar. All of the comparative studies published in the PubMed, Cochrane Library, Medline, Web of Science, and EMBASE databases as of 1 October 2023 were included. All outcomes were analysed using Review
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Effects of ultrasound-guided lumbar plexus and sacral plexus block combined with general anesthesia on the anesthetic efficacy and surgical outcomes in elderly patients undergoing intertrochanteric fracture surgery: a randomized controlled trial J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-07 Ji Feng, Guangyan Tang, Yunhua Shui, Jilin Xiang, Zhijun Qin
Surgery for intertrochanteric fractures in elderly patients is challenging due to the risk of severe pain and significant stress responses. We investigated the effects of a combined approach of ultrasound-guided lumbar plexus and sacral plexus block with general anesthesia on anesthetic efficacy and surgical outcomes in these patients. A randomized controlled trial was conducted involving 150 elderly
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Comparison of outcomes after total hip arthroplasty between patients with osteonecrosis of the femoral head in Association Research Circulation Osseous stage III and stage IV: a five-year follow-up study J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-06 Tianyu Wang, Dongwei Wu, Chengsi Li, Xinqun Cheng, Zhenbang Yang, Yingze Zhang, Yanbin Zhu
No large cohort study has evaluated the surgical outcomes of THA between different stages of ONFH patients. This study aimed to compare the surgical outcomes of ONFH patients who underwent THA in ARCO stage III versus IV, in terms of operative parameters, one-year hip function assessments and postoperative at least five-year complications, to inform optimized management of ONFH. From our prospectively
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Investigating the in vitro antibacterial efficacy of composite bone cement incorporating natural product-based monomers and gentamicin J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-06 Yu-Chen Kan, Rui Guo, Yang Xu, Lu-Yang Han, Wen-Han Bu, Long-Xu Han, Jian-Jun Chu
The objective of this study is to investigate the impact of four natural product extracts, namely, aloe-emodin, quercetin, curcumin, and tannic acid, on the in vitro bacteriostatic properties and biocompatibility of gentamicin-loaded bone cement and to establish an experimental groundwork supporting the clinical utility of antibiotic-loaded bone cements (ALBC). Based on the components, the bone cement
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Modified gastro-soleus turn-down flap for chronic or neglected achilles tendon ruptures J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-06 Mohamed A. A. Ibrahim, Mohamed G. Abdelkader, Samir A. Nematallah, Gamal A. Elsawy, Sameh A. Alghandour, Lotfy M. Shwitter
Achilles’ tendon chronic rupture is a common entity that is usually misdiagnosed or mistreated. Hence, she was presented to us later or with complications affecting her gait. Surgical resection is needed to either bridge the gap or reinforce the strength of the tendon repair. Our study's goal was to assess the clinical results of repairing chronic Achilles’ tendon lesions employing the middle segment
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Clinical effects of arthroscopic-assisted uni-portal spinal surgery and unilateral bi-portal endoscopy on unilateral laminotomy for bilateral decompression in patients with lumbar spinal stenosis: a retrospective cohort study J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-05 Fang Wang, Rui Wang, Chengyi Zhang, En Song, Fengtao Li
To investigate the clinical effectiveness of Arthroscopic-assisted Uni-portal Spinal Surgery (AUSS) in the treatment of lumbar spinal stenosis. A total of 475 patients with lumbar spinal stenosis from January 2019 to January 2023 were included in this study. Among them, 240 patients were treated with AUSS (AUSS group); the other 235 patients were treated with unilateral bi-portal endoscopy treatment
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Biomechanical characteristics of Sanders type II and III calcaneal fractures fixed by open reduction and internal fixation and percutaneous minimally invasive fixation J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-05 Wu Ren, Kailu Zhang, Ziya Zhao, Xueling Zhang, Fei Lin, Yawei Li, Ke Bao, Jun Yang, Jinlong Chang, Jia Li
This work investigated the differences in the biomechanical properties of open reduction and internal fixation (ORIF) and percutaneous minimally invasive fixation (PMIF) for the fixation of calcaneal fractures (Sanders type II and III calcaneal fractures as examples) through finite element analysis. Based on CT images of the human foot and ankle, according to the principle of three-point fixation,
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Management of rotator cuff injuries using allogenic platelet-rich plasma J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-04 Ashim Gupta, Filippo Migliorini, Nicola Maffulli
Rotator cuff injuries are a major cause of shoulder pain, affecting the quality of life and producing a significant burden on healthcare systems. Conservative management modalities are prioritized, resorting to surgery only when required. The field of regenerative medicine involving the use of biologics, such as platelet-rich plasma (PRP), has evolved and shown potential for managing rotator cuff injuries
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Influence of diabetes on the risk of deep vein thrombosis of patients after total knee arthroplasty: a meta-analysis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-04 Jingzhi An, Li Han, Xiaojuan Ma, Yanyan Chang, Cuixin Zhang
Previous studies evaluating the influence of diabetes on the risk of deep vein thrombosis (DVT) after total knee arthroplasty (TKA) showed inconsistent results. The aim of the study was to systematically evaluate the association between diabetes and DVT after TKA in a meta-analysis. An extensive search was conducted in PubMed, Embase, and Web of Science to identify relevant cohort studies. Random-effects
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Comparative analysis of bone turnover markers in bone marrow and peripheral blood: implications for osteoporosis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-01 Chuan Jiang, Sibo Zhu, Wanda Zhan, Linbing Lou, Aoying Li, Jun Cai
This study examines bone turnover marker (BTM) variations between bone marrow and peripheral blood in osteoporotic and non-osteoporotic patients. BTMs offer insights into bone remodeling, crucial for understanding osteoporosis. A total of 133 patients were categorized into osteoporotic and non-osteoporotic cohorts. BTMs—C-telopeptide cross-linked type 1 collagen (β-CTX), serum osteocalcin (OC), Procollagen
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Correlation of serum and local CXCL13 levels with disease severity in patients with non-traumatic osteonecrosis of femoral head J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-01 Yong-Heng Zhao, Wen-Xiu Zhu, Qing-He Ye, Peng Zhang, Biao-Fang Wei
The primary aim of the present study was to explore the potential correlation of serum / local CXCL13 expressions and disease severity in non-traumatic osteonecrosis of the femoral head (NT-ONFH). In total, NT-ONFH patients (n = 130) together with healthy controls (HCs, n = 130) were included in this investigation. Radiographic progression was evaluated based on the imaging criteria outlined in the
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Levels of 91 circulating inflammatory proteins and risk of lumbar spine and pelvic fractures and peripheral ligament injuries: a two-sample mendelian randomization study J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-01 Huiyu Huang, Zhaojun Fu, Min Yang, Haigang Hu, Chao Wu, Lun Tan
Lumbar spine and pelvic fractures(LPF) are combined with peripheral ligament injuries(PLI), frequently. It has been reported that the site of fracture injury is usually paralleled by the secretion of inflammatory proteins. This study aimed to investigate the causal relationship between 91 circulating inflammatory proteins and LPF and PLI by using a Two-sample Mendelian randomization (MR) analysis.
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Bupivacaine–fentanyl isobaric spinal anesthesia reduces the risk of ICU admission in elderly patients undergoing lower limb orthopedic surgery J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-01 Wenxun Liu, Shuzhen Bao, Jiaxin Chen, Yan Li, Yinghua Gu, Qingshan Ye, Kerong Hai
To evaluate if bupivacaine–fentanyl isobaric spinal anesthesia could reduce the risk of ICU admission compared with general anesthesia in elderly patients undergoing lower limb orthopedic surgery. This study comprised a retrospective review of all lower limb orthopedic surgeries performed at our hospital between January 2013 and December 2019. According to anesthesia methods, patients were divided
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Efficacy and safety of the Latarjet procedure for the treatment of athletes with glenoid bone defects ≥ 20%: a single-arm meta-analysis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-01 Ling Wang, ShengRong He, Xia Wu, XiaoYu Lv, Tao Wang, HongBo Tan
The shoulder joint is the most commonly dislocated joint in the human body, and the recurrence rate exceeds 50% after nonsurgical treatment. Although surgical treatment reduces the recurrence rate, there is controversy regarding the optimal surgical approach. Previous studies suggest that the Latarjet procedure yields favourable outcomes for specific populations at risk of recurrence, such as competitive
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Inhibition of cc chemokine receptor 10 ameliorates osteoarthritis via inhibition of the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin pathway J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-01 Yan Luo, Feng Zhou, Xiaojing Wang, Runwei Yang, Yi Li, Xiaochun Wu, Bin Ye
Osteoarthritis (OA) is a joint disease characterized by inflammation and progressive cartilage degradation. Chondrocyte apoptosis is the most common pathological feature of OA. Interleukin-1β (IL-1β), a major inflammatory cytokine that promotes cartilage degradation in OA, often stimulates primary human chondrocytes in vitro to establish an in vitro OA model. Moreover, IL-1β is involved in OA pathogenesis
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Clinical benefits of adding dexamethasone to local infiltration analgesia for simultaneous bilateral total hip or knee arthroplasty J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-01 Xiao-Dong Wang, Qing-Wei Meng, Fu-Shan Xue
To the editor, By conducting a randomized controlled double-blind trial of 105 patients who received simultaneous bilateral total hip or knee arthroplasty, Wang et al. [1] showed that the addition of dexamethasone to the local infiltration analgesia (LIA) mixture decreased total opioid consumption, frequency of using patient-controlled intravenous analgesia (PCIA) and the occurrence of postoperative
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HSPB1 as an RNA-binding protein mediates the pathological process of osteoarthritis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-01 Qiang Fu, Yi Li, Chunhua Shi
Heat-shock protein beta1 (HSPB1) is a member of the small HSP family, downregulated in osteoarthritis (OA) chondrocytes and demonstrated the capacity to serve as an RNA-binding protein (RBP). This work aimed to explore the profile of HSPB1 bound RNA and reveal the potential regulation mechanism of HSPB1 in OA. In this work, we captured an unbiased HSPB1-RNA interaction map in Hela cells using the iRIP-seq
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Lever sign test for anterior cruciate ligament injuries: a diagnostic meta-analysis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-03-01 Weili Feng
Sports-related ACL (anterior cruciate ligament) injuries are frequent. Successful management requires early diagnosis and treatment. One of the clinical tests used to identify ACL damage is the lever sign test. This meta-analysis aimed to assess the lever sign test's diagnostic efficacy for ACL injuries. An extensive investigation of the Cochrane Library, Embase, and PubMed databases was conducted
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The effect of the whole-process care model of the medical union on the improvement of kinesiophobia and bone mineral density in patients with osteoporosis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-27 Xiaoli Qian, Xiaodong Cao, Liyan Zhu, Xiaojuan Yao, Lina Gu, Xin Yu
To observe the effect of the whole-process care model of the medical union on the improvement of kinesiophobia and bone mineral density in patients with osteoporosis. In this descriptive study, a convenient sampling method was used to select 148 patients with osteoporosis who visited the hospital from January 2020 to December 2021. Patients aged ≥ 18 years and diagnosed with osteoporosis through quantitative
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Biomechanical comparison of all-polyethylene total knee replacement and its metal-backed equivalent on periprosthetic tibia using the finite element method J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-23 Vasileios Apostolopoulos, Petr Boháč, Petr Marcián, Luboš Nachtnebl, Michal Mahdal, Lukáš Pazourek, Tomáš Tomáš
Total knee arthroplasty (TKA) with all-polyethylene tibial (APT) components has shown comparable survivorship and clinical outcomes to that with metal-backed tibial (MBT). Although MBT is more frequently implanted, APT equivalents are considered a low-cost variant for elderly patients. A biomechanical analysis was assumed to be suitable to compare the response of the periprosthetic tibia after implantation
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Incidence and influence factors of venous thromboembolism in traumatic rib fracture patient: a multicenter study J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-23 Dongsheng Zhang, Yi Yang, Yunfeng Yi, Dongbin Wang, Lei Jiang, Hai Huang, Longyu Jin, Hui Meng, Fei Xia, Guangwei Guo
This study aimed to determine the incidence and influencing factors of venous thromboembolism (VTE) in patients with traumatic rib fractures. The retrospective study analyzed medical records of patients with traumatic rib fractures from 33 hospitals. The overall incidence of VTE in hospitalized patients with traumatic rib fractures was 8.1%. Patients with isolated traumatic rib fractures had a significantly
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Saikosaponin D alleviates inflammatory response of osteoarthritis and mediates autophagy via elevating microRNA-199-3p to target transcription Factor-4 J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-22 Ming Yan, DaWei Zhang, Min Yang
This study was to investigate the underlying mechanism by which Saikosaponin D (SSD) mitigates the inflammatory response associated with osteoarthritis (OA) and regulates autophagy through upregulation of microRNA (miR)-199-3p and downregulation of transcription Factor-4 (TCF4). A mouse OA model was established. Mice were intragastrically administered with SSD (0, 5, 10 μmol/L) or injected with miR-199-3p
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Comparison of minimally invasive transforaminal lumbar interbody fusion (Mis-TLIF) with bilateral decompression via unilateral approach and open-TLIF with bilateral decompression for degenerative lumbar diseases: a retrospective cohort study J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-20 Fengzhao Zhu, Dongqing Jia, Yaqing Zhang, Chencheng Feng, Ya Ning, Xue Leng, Yue Zhou, Changqing Li, Bo Huang
Presently, no study has compared the clinical outcomes of minimally invasive transforaminal lumbar interbody fusion (Mis-TLIF) with bilateral decompression via the unilateral approach (BDUA) and Open-TLIF with bilateral decompression for degenerative lumbar diseases (DLD). We aimed to compare the clinical outcomes of through Mis-TLIF combined with BDUA and Open-TLIF with bilateral decompression for
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Arthroscopic wafer procedure versus ulnar shortening osteotomy for ulnar impaction syndrome: a systematic review and meta-analysis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-20 Haifeng Shi, Yongjing Huang, Yong Shen, Ke Wu, Zhihai Zhang, Qian Li
This study aimed to systematically compare the efficacy and safety of arthroscopic wafer procedure (AWP) versus ulnar shortening osteotomy (USO) for ulnar impaction syndrome (UIS) treatment. All the studies included in this meta-analysis compared the efficacy of AWP to USO for UIS and were acquired through a comprehensive search across multiple databases. The meta-analysis was performed by calculating
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Intraoperative femurofibular angle combined with tibiofibular angle measurement has fewer correction errors in open-wedge high tibial osteotomy J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-19 Chen Zhao, Bing Zhang, Xuejiao Liu, Bo Li, Liang Bao, Cong Liu, Lihong Fan
This study aimed to verify the accuracy of intraoperative femurofibular angle combined with tibiofibular angle (FFA–TFA) measurement and compare it with traditional alignment line methods in open-wedge high tibial osteotomy (OWHTO). A total of 174 knees of 122 patients undergoing OWHTO and using an alignment line or FFA–TFA measurement as an index of optimal correction were included in this retrospective
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Several first-line anti-hypertensives act on fibrosarcoma progression and PD1ab blockade therapy J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-19 Jianwen Sun, Chaoxiong Zhang, Xinhao Su, Haoyun Zhou, Siyun Zhou, Minjie Jiang, Binbo Fang
Patients are typically diagnosed with both hypertension and fibrosarcoma. Medical oncologists must prescribe suitable anti-hypertensive medications while considering anti-tumor drugs. Recently, immunotherapy has become prominent in cancer treatment. Nonetheless, it is unknown what role anti-hypertensive medications will play in immunotherapy. We examined the effects of six first-line anti-hypertensive
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Periostin/Bone Morphogenetic Protein 1 axis axis regulates proliferation and osteogenic differentiation of sutured mesenchymal stem cells and affects coronal suture closure in the TWIST1+/− mouse model of craniosynostosis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-19 ShuBin Feng, Qiang Feng, LiuJian Dong, Qiang Lv, ShiYue Mei, YaoDong Zhang
The pathogenesis of coronal suture craniosynostosis is often attributed to the dysregulated cellular dynamics, particularly the excessive proliferation and abnormal osteogenic differentiation of suture cells. Despite its clinical significance, the molecular mechanims of this condition remain inadequately understood. This study is dedicated to exploring the influence of the Periostin/Bone Morphogenetic
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Correction: 6 February 2023, orthopedic experience in Kahramanmaraş earthquake and surgical decision in patients with crush syndrome J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-19 Bugra Kundakci, Akif Mirioglu, Mustafa Tekin, Melih Bagir, Omer Sunkar Bicer, Yusuf Kemal Arslan, Cenk Ozkan, Hilmi Serdar Ozbarlas
Correction: Journal of Orthopaedic Surgery and Research (2013) 18:537 https://doi.org/10.1186/s13018-023-04001-2 In this article ref. 23 Epstein FH, Odeh M. The role of reperfusion-ınduced ınjury in the pathogenesis of the crush syndrome. New Engl J Med. 1991;324:1417–22. https://doi.org/10.1056/nejm199105163242007 was incorrect and should have been Odeh M. The role of reperfusion-induced injury in
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Antibacterial activities of titanium dioxide (TiO2) nanotube with planar titanium silver (TiAg) to prevent orthopedic implant infection J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-16 Lihong Zhang, Zhihui Jin
Orthopedic implant infection has become a common catastrophic complication after various orthopedic implants, which can lead to prolonged use of antibiotics and even surgical failure. The quality of care (QoC) of orthopedic implant infection is very important. Titanium dioxide (TiO2) nanotube array with planar TiAg was prepared, and their antibacterial rates were tested. 400 patients hospitalized in
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Intraoperative capsule protection can reduce the potential risk of adjacent segment degeneration acceleration biomechanically: an in silico study J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-16 Fei Huang, Gang Huang, Junpengli Jia, Shihao Lu, Jingchi Li
The capsule of the zygapophyseal joint plays an important role in motion segmental stability maintenance. Iatrogenic capsule injury is a common phenomenon in posterior approach lumbar interbody fusion operations, but whether this procedure will cause a higher risk of adjacent segment degeneration acceleration biomechanically has yet to be identified. Posterior lumbar interbody fusion (PLIF) with different
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Biomechanical comparison of static and dynamic cervical plates in terms of the bone fusion, tissue degeneration, and implant behavior J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-15 Tzu-Tsao Chung, Dueng-Yuan Hueng, Shang-Chih Lin
Using an anterior cervical fixation device in the anterior cervical discectomy and fusion (ACDF) has evolved to various systems of static and dynamic cervical plates (SCP and DCP). Dynamic cervical plates have been divided into three categories: the rotational (DCP-R), translational (DCP-T), and hybrid (DCP-H) joints. However, little studies have been devoted to systematically investigate the biomechanical
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The association of ICUC trauma score and quick DASH in a distal radius fracture cohort J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-15 Wen-Chih Liu, Magdalena Hartwich, Joseph J. Locascio, Pietro Regazzoni, Jesse B. Jupiter, Alberto Fernandez Dell’Oca
This study evaluates the association between ICUC trauma and short-form Disabilities of the Arm, Shoulder, and Hand Questionnaire (Quick DASH) scores among patients who underwent surgery for distal radius fractures. This research gathered patient-reported outcomes (PROs) from patients registered in the ICUC database at a single trauma center. The study involved 76 adult patients who underwent surgical
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Translation, reliability and validity of the Turkish versions of Norwich Patellar Instability score and The Banff Patellar Instability Instrument 2.0 J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-14 Engin Turkay Yilmaz, Ibrahim Mehmet Goymen, Melih Oral, Ozan Tuncay, Gokay Dursun, Egemen Turhan, Ahmet Mazhar Tokgozoglu
Current treatment options for patellofemoral (PF) instability have required functional scoring systems. The Banff Patellar Instability Instrument (BPII) 2.0 and Norwich Patellar Instability (NPI) scores were explicitly created to meet the need to evaluate PF instability. Different patient-reported outcome measurements (PROMs) are used to evaluate anterior knee problems. To test the validity and reliability
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Application of a combined cancellous lag screw enhances the stability of locking plate fixation of osteoporotic lateral tibial plateau fracture by providing interfragmentary compression force J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-14 Jiang Jiang, Daqiang Xu, Zhenhua Ji, Fei Wang, Rui Jia, Jun Wang, Hong Hong, Hongtao Zhang, Jianyi Li
Insufficient interfragmentary compression force (IFCF) frequently leads to unstable fixation of osteoporotic lateral tibial plateau fractures (OLTPFs). A combined cancellous lag screw (CCLS) enhances IFCF; however, its effect on OLTPF fixation stability remains unclear. Therefore, we investigated the effect of CCLS on OLTPF stability using locking plate fixation (LPF). Twelve synthetic osteoporotic
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Sagittal imbalance syndrome, a new concept, helps determining a long fusion for patients with degenerative lumbar spinal stenosis and severe global sagittal imbalance J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-13 Shibao Lu, Weiguo Zhu, Yu Wang, Chao Kong, Wei Wang, Xiaolong Chen, Xiangyu Li
To retrospectively investigate the postoperative clinical and radiographic outcomes in elderly patients with degenerative lumbar spinal stenosis (DLSS) and severe global sagittal imbalance who underwent different fusion levels. A total of 214 patients with DLSS and severe global sagittal imbalance were included. Sagittal imbalance syndrome was defined as the severe decompensated radiographic global
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The effects of resveratrol in animal models of primary osteoporosis: a systematic review and meta-analysis J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-13 Rongxian An, Qian Luo, Lei Li, Dinglu Cui, Jingchun Jin
There is still a lack of sufficient evidence-based medical data on the effect of resveratrol (Res) on primary osteoporosis (OP). This meta-analysis aimed to comprehensively evaluate the role of Res in animal models of primary OP. The PubMed, Cochrane Library, Web of Science and Embase databases were searched up to August 2023. The risk of bias was assessed by the SYRCLE RoB tool. Random- or fixed-effects
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Impact of sustentaculum tali screw positioning on radiographic and functional outcomes in calcaneal fractures J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-12 Zihua Li, Fajiao Xiao, Hui Huang, Jiang Xia, Haichao Zhou, Bing Li, Yunfeng Yang
To investigate whether accurate placement of sustentaculum tali screws have the impacts on the clinical efficacy of calcaneal fractures. A retrospective analysis of 72 cases (73 feet) of calcaneal fractures from September 2015 to September 2019 treated with open reduction and internal fixation with sustentaculum tali screws was conducted. Patients were divided into the sustentaculum tali fixation group
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The pandemic is gone but its consequences are here to stay: avascular necrosis following corticosteroids administration for severe COVID-19 J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-12 Filippo Migliorini, Nicola Maffulli, Tapish Shukla, Riccardo D’Ambrosi, Mohit Singla, Abhishek Vaish, Raju Vaishya
In patients with COVID-19 infection and respiratory insufficiency, corticosteroid (CCS) administration is recommended. Among the wide range of complications and interactions, time-limited high-dose CCS administration might promote avascular necrosis (AVN) in a cumulative dose. This systematic review updated the current evidence and characterises the trend of AVN following time-limited high-dose CCS
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MicroRNA-877-5p promotes osteoblast differentiation by targeting EIF4G2 expression J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-12 YingChao Shen, Yang Zhang, Qiang Wang, Bo Jiang, XiaoWei Jiang, Bin Luo
Stimulating bone formation potentially suggests therapeutics for orthopedic diseases including osteoporosis and osteoarthritis. Osteoblasts are key to bone remodeling because they act as the only bone-forming cells. miR-877-5p has a chondrocyte-improving function in osteoarthritis, but its effect on osteoblast differentiation is unknown. Here, miR-877-5p-mediated osteoblast differentiation was studied
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Correction: Evidence-based informed consent form for total knee arthroplasty J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-12 Satvik N. Pai, Madhan Jeyaraman, Nicola Maffulli, Naveen Jeyaraman, Filippo Migliorini, Ashim Gupta
Correction: Journal of Orthopaedic Surgery and Research https://doi.org/10.1186/s13018-023-03647-2 Following publication of the original article [1], the authors identified an error in the author name of Nicola Maffulli. The incorrect author name is: Nicola Maffuli The correct author name is: Nicola Maffulli The author group has been updated above and the original article [1] has been corrected. Pai
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Surgical management of chronic Achilles tendon rupture: evidence-based guidelines J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-10 Shi-Ming Feng, Nicola Maffulli, Francesco Oliva, Amol Saxena, Yue-Feng Hao, Ying-Hui Hua, Hai-Lin Xu, Xu Tao, Wei Xu, Filippo Migliorini, Chao Ma
Chronic Achilles tendon ruptures (CATR) often require surgical intervention to restore function. Despite numerous treatment modalities available, the optimal management strategy remains controversial given the limited high-quality evidence available. This article aims to provide evidence-based guidelines for the surgical management of CATR through a comprehensive systematic review of the available
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Endoscopic peroneus brevis tendon transfer for chronic ruptures of the Achilles tendon: surgical technique J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-10 Nicola Poeta, Nicola Maffulli, Fabrizio Bucolo, Christel Charpail, Filippo Migliorini, Stéphane Guillo
Chronic Achilles tendon rupture is usually defined as a rupture diagnosed 4–6 weeks after injury. The management of chronic Achilles tendon rupture (CATR) is a topic of hot debate, and no consensus has been achieved. Surgical management of CATR is recommended. Several approaches, techniques, and grafts have been described. Open techniques carry a high risk of wound breakdown, infection, and necessitate
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Diagnosis and management of Achilles tendon ailments: the Scottish mist J. Orthop. Surg. Res. (IF 2.6) Pub Date : 2024-02-09 Nicola Maffulli, John B. King, Filippo Migliorini, Otto Chan, Nat Padhiar, Filippo Spiezia
The diagnosis and management of Achilles tendon ailments continue to be widely discussed by the scientific community. Also, the nomenclature used to describe the tendinopathic lesion in patients changed over the last decades together with the evolution in the knowledge of the physiopathology of Achilles tendinopathy, and unfortunately, through ignorance and possibly laziness, confusion still abounds