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No significant differences in 60-day postoperative complication rates between conventional and shortened stems J. Exp. Orthop. Pub Date : 2023-12-28 Guillaume Girardot, Sylvain Guy, Nicolas Bonin
To compare 60-day complication rates, radiographic outcomes, and clinical outcomes following primary THA with conventional versus shortened stems, in a large cohort study. The authors reviewed a consecutive series of 800 primary THAs, of which 781 met the inclusion/exclusion criteria: 395 received a conventional stem and 386 received a shortened stem. Intraoperative and postoperative complications
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Correction: Soft‑tissue tension during total hip arthroplasty measured in four patients and predicted using a musculoskeletal model J. Exp. Orthop. Pub Date : 2023-12-28 Masaru Higa, Hiromasa Tanino, Hiroshi Ito, Scott A. Banks
Correction: J Exp Orthop 10, 130 (2023) https://doi.org/10.1186/s40634-023-00689-7. Following publication of the original article [1], the author reported that the authors’ affiliation assignment was incorrect. Masaru Higa1,2,3, Hiromasa Tanino1,2,3, Hiroshi Ito1,2,3 and Scott A. Banks1,2,3 The correct version is shown in the authorgroup section above and the original article has been corrected. Higa
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Correction: Posterior stability of the shoulder depends on acromial anatomy: a biomechanical study of 3D surface models J. Exp. Orthop. Pub Date : 2023-12-26 Bettina Hochreiter, Silvan Beeler, Simon Hofstede, Bastian Sigrist, Jess G. Snedeker, Christian Gerber
Correction: J Exp Orthop 10, 59 (2023) https://doi.org/10.1186/s40634-023-00623-x Following publication of the original article [1], the authors reported that the cited number of the ethical approval “2020-01558” is incorrect. It should be corrected to “2020-00389”. The original article has been corrected. Hochreiter B, Beeler S, Hofstede S et al (2023) Posterior stability of the shoulder depends on
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The reimbursement system can influence the treatment choice and favor joint replacement versus other less invasive solutions in patients affected by osteoarthritis J. Exp. Orthop. Pub Date : 2023-12-23 Luca De Marziani, Angelo Boffa, Alessandro Di Martino, Luca Andriolo, Davide Reale, Alessio Bernasconi, Valentina Rita Corbo, Francesca de Caro, Marco Delcogliano, Giorgio di Laura Frattura, Giovanni Di Vico, Andrea Fabio Manunta, Arcangelo Russo, Giuseppe Filardo
The aim of this study was to assess how physicians perceive the role of the reimbursement system and its potential influence in affecting their treatment choice in the management of patients affected by osteoarthritis (OA). A survey was administered to 283 members of SIAGASCOT (Italian Society of Arthroscopy, Knee, Upper Limb, Sport, Cartilage and Orthopaedic Technologies), a National scientific orthopaedic
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Skin sensory alteration and kneeling ability following cruciate retaining total knee arthroplasty are not affected by the incision position: A randomised controlled trial of simultaneous bilateral surgery J. Exp. Orthop. Pub Date : 2023-12-23 Sergio Barroso Rosa, Matthew Wilkinson, Peter McEwen, Levi Morse, Andrea Grant, Kenji Doma, Charles Haward, Matthew Rikard-Bell
The purpose of this randomised controlled trial was to assess the impact of skin incision location on the patients’ ability to kneel. A total of 29 patients undergoing bilateral total knee arthroplasty (58 knees) were randomised to receive a lateral or midline incision, with the contralateral limb receiving the alternative option. Cruciate retaining implants were used in all cases by three experienced
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The role of arthroscopy in the management of adult elbow trauma J. Exp. Orthop. Pub Date : 2023-12-22 Maria Valencia, AM. Foruria
Fractures around the elbow are often challenging to treat and in most cases require an extensive approach. Since the development of elbow arthroscopy, most authors have pointed out the potential advantages of a less invasive technique that can be useful for visualization and reduction of the articular fragments with an eventual percutaneous fixation. Arthroscopic techniques provide a limited exposure
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The size of the Hill Sachs defect increases during reduction of a first time shoulder dislocation in older adults: a pilot study in 20 cases J. Exp. Orthop. Pub Date : 2023-12-22 Miguel Angel Ruiz Ibán, Roque Pérez Expósito, Agustina Vicente Bártulos, Rosa Vega Rodriguez, Raquel Ruiz Díaz, Jorge Diaz Heredia
To evaluate if the size of Humeral Hill-Sachs Defects (HSDs) increases during reduction in the emergency department (ED) in subjects that have a first-time anterior shoulder dislocation. Subjects more than 18 years old presenting to the ED a first-time anterior shoulder dislocation were included. A computed tomography was performed prior to any reduction attempt (Pre-CT). The shoulder was reduced in
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A non-weight bearing protocol after ACL reconstruction improves static anterior tibial translation in patients with elevated slope and increased weight bearing tibial anterior translation J. Exp. Orthop. Pub Date : 2023-12-20 Iacopo Romandini, Nicolas Cance, Michael J. Dan, Tomas Pineda, Benoit Pairot de Fontenay, Guillaume Demey, David H. Dejour
Aim of this study is to evaluate the impact of a non-weight bearing (NWB) protocol within 21 post-operative days after anterior cruciate ligament (ACL) reconstruction on static and dynamic anterior tibial translations (SATT and DATT, respectively). The hypothesis is that delayed WB would improve ATT at 9 months follow-up. A series of patients treated with ACL reconstruction was retrospectively reviewed
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The quest for optimal femoral torsion angle measurements: a comparative advanced 3D study defining the femoral neck axis J. Exp. Orthop. Pub Date : 2023-12-18 Bert Van fraeyenhove, Jeroen C. F. Verhaegen, Jonas Grammens, Gino Mestach, Emmanuel Audenaert, Annemieke Van Haver, Peter Verdonk
There is high variability in femoral torsion, measured on two-dimensional (2D) computed tomography (CT) scans. The aim of this study was to find a reliable three-dimensional (3D) femoral torsion measurement method, assess the influence of CAM deformity on femoral torsion measurement, and to promote awareness for the used measurement method. 3D models of 102 dry femur specimens were divided into a CAM
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Effect of lateral hinge fractures for bone union and clinical outcomes following opening-wedge distal tibial tubercle osteotomy in comparison with opening-wedge high tibial osteotomy J. Exp. Orthop. Pub Date : 2023-12-14 Shuhei Otsuki, Kuniaki Ikeda, Takashi Ishitani, Yoshinori Okamoto, Hitoshi Wakama, Masashi Neo
Although the effects of lateral hinge fractures (LHF) on bone union and clinical outcomes after opening-wedge high tibial osteotomy (OWHTO) have been established, the effects of LHF after opening-wedge distal tibial tubercle osteotomy (OWDTO) are unclear. We hypothesised that LHF after OWDTO would be associated with delayed bone union and result in poorer clinical outcomes than expected for LHF after
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Tough gel adhesive is an effective method for meniscal repair in a bovine cadaveric study J. Exp. Orthop. Pub Date : 2023-12-14 David Mazy, Christopher Chung-Tze-Cheong, Zhenwei Ma, Ran Huo, Stephanie Lamer, Jianyu Li, Marie-Lyne Nault
To test tough gel adhesives to repair meniscus tears under relevant loading conditions and determine if they have adequate biomechanical properties to repair meniscus tears in a bovine cadaveric study. Cyclic compression tests on 24 dissected bovine knees were performed. The tough gel adhesive was used either as an adhesive patch or as a coating bonded onto commercially available surgical sutures.
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Virtual reality simulation training improve diagnostic knee arthroscopy and meniscectomy skills: a prospective transfer validity study J. Exp. Orthop. Pub Date : 2023-12-14 Alexandre Tronchot, Tiphaine Casy, Nicolas Vallee, Harold Common, Hervé Thomazeau, Pierre Jannin, Arnaud Huaulmé
Limited data exist on the actual transfer of skills learned using a virtual reality (VR) simulator for arthroscopy training because studies mainly focused on VR performance improvement and not on transfer to real word (transfer validity). The purpose of this single-blinded, controlled trial was to objectively investigate transfer validity in the context of initial knee arthroscopy training. For this
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Surgical technique: posterior cruciate ligament (PCL) reconstruction using double posteromedial arthroscopic portals J. Exp. Orthop. Pub Date : 2023-12-13 Gian Andrea Lucidi, Romain Seil, Piero Agostinone, Cécile Toanen, Alberto Grassi, Stefano Zaffagnini
The posterior cruciate ligament (PCL) reconstruction is a technically demanding surgical procedure that requires optimal identification of both the femoral and the tibial anatomical footprints. To aid the tibial tunnel placement and many authors recommend creating a posteromedial (PM) portal. The further addition of a second PM portal, which could be used as a “working portal”, may further allow a
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Case report: unusual posteromedial capsular lesion with posterior lateral meniscus root tear in two patients with constitutional genu recurvatum presenting after an acute ACL injury J. Exp. Orthop. Pub Date : 2023-12-13 Giulio Vittone, Caroline Mouton, Jérôme Valcarenghi, Jérémie Dor, Romain Seil
Ramp lesions of the medial meniscus and posterior lateral meniscus root tears (LMPRT) can be present simultaneously in up to 8% of patients undergoing anterior cruciate ligament (ACL) reconstruction. The prevalence of these complex and highly unstable meniscal tears increases exponentially with the severity of the injury. The posteromedial capsule (PMC) has often been disregarded in the past when discussing
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Extrusion of the anterior segment of the medial meniscus extrusion initiates knee osteoarthritis: evaluation using magnetic resonance imaging J. Exp. Orthop. Pub Date : 2023-12-13 Atsushi Ichiba, Eichi Ito, Keiichiro Kino
Meniscus extrusion contributes to the progression of knee osteoarthritis (OA). It is not clear which site of the medial meniscus (MM) extrusion (MME) is greatest. Moreover, the relationship between sites of MME and progression of OA has not yet been elucidated. The purpose of this study was to determine which sites of MME that showed the greatest extrusion and to investigate the relationship between
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No difference in Oxford Knee Score between medial and lateral unicompartmental knee arthroplasty after two years of follow-up: a clinical trial J. Exp. Orthop. Pub Date : 2023-12-08 Filippo Migliorini, Federico Cocconi, Julia Prinz, Nicola Ursino, Laura Mangiavini, Riccardo D’Ambrosi
In patients with monocompartmental knee osteoarthritis, unicompartmental knee arthroplasty (UKA) can be performed. This study compared the medial versus lateral UKA in patients with monocompartimental knee arthroplasty. It was hypothesised that both implants achieve a similar outcome in OKS. The UKAs were fixed-bearing medial PPK (Zimmer-Biomet, Warsaw, Indiana, USA) and fixed-bearing lateral Zuk (Lima
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Robotic-assisted total knee arthroplasty improves the rotational mismatch between femoral and tibial components, but not the forgotten joint score 12: a single-center retrospective cohort study J. Exp. Orthop. Pub Date : 2023-12-08 Ayakane Yamamoto, Takao Kaneko, Kazutaka Takada, Shu Yoshizawa
The primary aim of this study was to compare postoperative short-term patient reported outcome measurements (PROMs) and rotational mismatch between femoral and tibial following conventional jig-based total knee arthroplasty (Conv-TKA) versus robotic-assisted TKA (RA-TKA) using three-dimensional computed tomography (3DCT) measurements. This retrospective, consecutive case–control trial included 83 patients
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Does posterior tibial slope laterality exist? A matched cohort study between ACL-injured and non-injured knees J. Exp. Orthop. Pub Date : 2023-12-07 Keiji Tensho, Daiki Kumaki, Kazushige Yoshida, Hiroki Shimodaira, Hiroshi Horiuchi, Jun Takahashi
The purpose of this study is to examine 1) the degree and frequency of laterality in posterior tibial slope (PTS) with control and anterior cruciate ligament (ACL) injury groups and 2) the laterality of PTS between sides of injury and dominant legs in patients with primary ACL injuries. A total of 187 consecutive patients with clinically diagnosed noncontact ACL injuries and an age- and sex-matched
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A systematic approach to managing complications after proximal tibial osteotomies of the knee J. Exp. Orthop. Pub Date : 2023-12-06 Jérôme Valcarenghi, Giulio Vittone, Caroline Mouton, Alexandre Coelho Leal, Maximiliano Ibañez, Alexander Hoffmann, Dietrich Pape, Matthieu Ollivier, Romain Seil
Proximal tibial osteotomy (PTO) is an effective procedure for active and young adult patients with symptomatic unicompartmental osteoarthritis and malalignment. They were considered technically demanding and prone to various complications related to the surgical technique, biomechanical or biological origin. Among the most important are hinge fractures and delayed or non-healing, neurovascular complications
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Soft-tissue tension during total hip arthroplasty measured in four patients and predicted using a musculoskeletal model J. Exp. Orthop. Pub Date : 2023-12-05 Masaru Higa, Hiromasa Tanino, Hiroshi Ito, Scott A. Banks
Soft-tissue tension around the hip joint is related to the incidence of dislocation after total hip arthroplasty (THA), but it remains difficult to quantify the soft-tissue tension during surgery. In this study, a three-dimensional force sensor-instrumented modular femoral head was developed and used to quantify soft-tissue tension during THA. The forces at the hip joint were also calculated using
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Defining hip cartilage repair: a modified delphi study to establish the Magnetic Resonance Evaluation of the Repair of Cartilage in the Hip (MERCH) score J. Exp. Orthop. Pub Date : 2023-12-05 Olufemi R. Ayeni
To develop a standardized scoring system to evaluate pre- to post-operative repair or reconstruction of hip cartilage using magnetic resonance imaging (MRI). A two-phase modified Delphi study was conducted. Phase 1 involved a survey with suggested criteria and diagrams to define various stages of articular cartilage repair and phase 2 involved an expert consensus meeting that discussed the survey responses
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ChatGPT and large language models in orthopedics: from education and surgery to research J. Exp. Orthop. Pub Date : 2023-12-01 Srijan Chatterjee, Manojit Bhattacharya, Soumen Pal, Sang-Soo Lee, Chiranjib Chakraborty
ChatGPT has quickly popularized since its release in November 2022. Currently, large language models (LLMs) and ChatGPT have been applied in various domains of medical science, including in cardiology, nephrology, orthopedics, ophthalmology, gastroenterology, and radiology. Researchers are exploring the potential of LLMs and ChatGPT for clinicians and surgeons in every domain. This study discusses
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Superior bone fixation of conical compared with hemispherical trapezial cup design: an experimental radiostereometry study J. Exp. Orthop. Pub Date : 2023-11-30 Maiken Stilling, Lene Dremstrup, Torben Bæk Hansen, Janni Kjærgaard Thillemann
The most used cup designs for trapeziometacarpal (TMC) arthroplasty are of hemispherical and conical geometrical shape. Using a validated pig bone model, we compared the bone fixation using radiostereometry (RSA). Twenty saddle-shaped pig forefoot bones were prepared with insertion of bone markers and reaming. Hemispherical Type T cups (Beznoska, Kladno, Czech Republic) (N = 10) and conical Moovis
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Femoral head translation in borderline and definite dysplastic hips during weight-bearing: 2D/3D image registration analysis J. Exp. Orthop. Pub Date : 2023-11-29 Shinichiro Sakai, Tatsuhiko Kutsuna, Kohei Kono, Tomofumi Kinoshita, Naohiko Mashima, Masaki Takao
The aims of this study were to 1) assess femoral head translation during weight-bearing in symptomatic developmental dysplasia of the hip (DDH) and 2) compare it between borderline DDH and definite DDH. The study included four individuals with borderline DDH and nine with definite DDH, scheduled for periacetabular osteotomy. Anteroposterior X-ray images of the hip joint were obtained in the standing
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Knee extension contracture with fixed anterior tibia subluxation treated with PCL release and quadricepsplasty: a case report J. Exp. Orthop. Pub Date : 2023-11-29 Dong Woon Kim, Marcin Mostowy, Przemyslaw A. Pękala, Michalina Bawor, Nicholas I. Kennedy, Robert F. LaPrade, Konrad Malinowski
58-year-old male presented with knee extension contracture (25°) with iatrogenic fixed anterior tibial subluxation. Consecutive arthroscopic arthrolysis, manipulation under anesthesia, and quadriceps-Z-plasty during one surgery failed to restore flexion. Therefore, shortened posterior cruciate ligament was released, which eliminated subluxation and allowed 115° flexion. Despite physiotherapy, flexion
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Near-Infrared Spectroscopy measurements are reliable for studying patellar bone hemodynamics and affected by venous occlusion, but not by skin compression J. Exp. Orthop. Pub Date : 2023-11-29 Martin J. Ophey, Anne Westerweel, Maxime van Oort, Robert van den Berg, Gino M. M. J. Kerkhoffs, Igor J. R. Tak
According to the homeostasis model, patellofemoral pain (PFP) results from disturbed homeostasis due to vascular insufficiency in the anterior knee. Near-Infrared Spectroscopy (NIRS) measures relative changes in concentrations (in µmol/cm2) of (de-)oxygenated hemoglobine (HHb and O2Hb). The aims were to: 1) investigate the characteristics of the NIRS signal derived from the patella during experiments
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Customized-individually-made origin® implants in total knee arthroplasty allow a reliable solution for accurate reproduction of planned implant positioning J. Exp. Orthop. Pub Date : 2023-11-28 Martin Sajan, Mohamad K. Moussa, Nicolas Lefèvre, Charles Payan, Eugénie Valentin, Alain Meyer, Yoann Bohu, Zeinab Khalaf, Olivier Grimaud, Antoinne Gerometta, Alexandre Hardy, Frédéric Khiami
To evaluate the accuracy and reproducibility of a patient-specific, customized individually made (CIM) total knee replacement (TKR) using the ORIGIN® prosthesis. This was a prospective study conducted at a University Hospital from January 15, 2019, to April 30, 2021. The study included patients planned for an ORIGIN® CIM TKR procedure. Exclusion criteria included revision surgery, severe deformity
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The morphology of the femoral posterior condyle affects the external rotation of the femur J. Exp. Orthop. Pub Date : 2023-11-25 Hiroki Hijikata, Osamu Tanifuji, Tomoharu Mochizuki, Takashi Sato, Satoshi Watanabe, Ryota Katsumi, Sho Hokari, Hiroyuki Kawashima
The purpose of this study was to identify factors related to the external rotation of the femur during knee flexion. Three-dimensional (3D) digital models of the femur and tibia were reconstructed from computed tomography images of 41 healthy Japanese subjects. Thirteen parameters related to femoral and tibial morphology and alignment of the lower extremities were evaluated, including the inclination
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Biomechanical evaluation of the spring ligament and the posterior tibial tendon by shear-waves elastography: validation of a reliable and reproducible measurement protocol J. Exp. Orthop. Pub Date : 2023-11-25 Grégoire Rougereau, Thibault Marty-Diloy, Marie Vigan, Kalinka Donadieu, Raphaël Vialle, Tristan Langlais, Alexandre Hardy
The anatomy of the spring ligament complex, as well as its pathology, is not well known in daily clinical practice. The purpose of this study was to evaluate the shear-wave elastography properties of the spring ligament and the posterior tibial tendon in healthy adults, and to assess the reliability and reproducibility of these measurements. Shear-wave elastography was used to evaluate both ankles
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Definitions and consequences of current alignment techniques and phenotypes in total knee arthroplasty (TKA) – there is no winner yet J. Exp. Orthop. Pub Date : 2023-11-22 Theofilos Karasavvidis, Cale A. Pagan Moldenhauer, Sébastien Lustig, Jonathan M. Vigdorchik, Michael T. Hirschmann
Dissatisfaction following total knee arthroplasty (TKA) has been extensively documented and it was attributed to numerous factors. In recent years, significant focus has been directed towards implant alignment and stability as potential causes and solutions to this issue. Surgeons are now exploring a more personalized approach to TKA, recognizing the importance of thoroughly understanding each individual
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A 5-year follow-up of Achilles tendon reconstruction using a full-thickness graft processed with the clearant method and retrograde fixation in the calcaneus: a case study of an amateur soccer player J. Exp. Orthop. Pub Date : 2023-11-22 Luis Alberto Buendia Saavedra
We present a case of a 41-year-old male amateur soccer player with no comorbidities, who experienced a rerupture of the Achilles tendon 5 years after his initial end-to-end plasty. To address this, we opted for a full-thickness reconstruction using a graft under the Clearant Process of the Achilles tendon. As an innovative approach, we proposed an alternative fixation technique, employing a Bio Composite
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Comparison of postoperative isokinetic quadriceps and gluteal muscular strength after primary THA: is there an early benefit through enhanced recovery programs? J. Exp. Orthop. Pub Date : 2023-11-22 Jan Reinhard, Annika Schreiner, Silvia Dullien, Julia Sabrina Götz, Franziska Leiss, Günther Maderbacher, Joachim Grifka, Felix Greimel
Although total hip arthroplasty (THA) is expected to result in a postoperative loss of muscular strength, no study investigated the benefit of an enhanced-recovery-after-surgery (ERAS) concept on the hip muscles in detail. We evaluated if (1) an ERAS-concept for primary THA results in reduced loss of muscular strength five days and four weeks postoperative. We (2) compared the two groups regarding
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A practical guide to the implementation of AI in orthopaedic research – part 1: opportunities in clinical application and overcoming existing challenges J. Exp. Orthop. Pub Date : 2023-11-16 Bálint Zsidai, Ann-Sophie Hilkert, Janina Kaarre, Eric Narup, Eric Hamrin Senorski, Alberto Grassi, Christophe Ley, Umile Giuseppe Longo, Elmar Herbst, Michael T. Hirschmann, Sebastian Kopf, Romain Seil, Thomas Tischer, Kristian Samuelsson, Robert Feldt
Artificial intelligence (AI) has the potential to transform medical research by improving disease diagnosis, clinical decision-making, and outcome prediction. Despite the rapid adoption of AI and machine learning (ML) in other domains and industry, deployment in medical research and clinical practice poses several challenges due to the inherent characteristics and barriers of the healthcare sector
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Autologous micro-fragmented adipose tissue injection provides significant and prolonged clinical improvement in patients with knee osteoarthritis: a case-series study J. Exp. Orthop. Pub Date : 2023-11-16 Arcangelo Russo, Gabriele Cortina, Vincenzo Condello, Marco Collarile, Roberto Orlandi, Riccardo Gianoli, Emanuele Giuliani, Vincenzo Madonna
Among the conservative strategies to manage patients with symptomatic knee osteoarthritis (OA), an innovative approach exploiting the regenerative capability of adipose tissue and its resident MSCs (Mesenchymal Stem Cells or Medicinal Signalling Cells) has been proposed with encouraging results. This study aims to demonstrate the benefits of autologous micro-fragmented adipose tissue (MAT) injection
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A new tibial insert design with ball-in-socket medial conformity and posterior cruciate ligament retention closely restores native knee tibial rotation after unrestricted kinematic alignment J. Exp. Orthop. Pub Date : 2023-11-15 Saúl Pacheco Elorza, Ed O’Donnell, Alexander J. Nedopil, Stephen M. Howell, Maury L. Hull
In total knee arthroplasty (TKA) with posterior cruciate ligament (PCL) retention, the medial and lateral insert conformity that restores in vivo native (i.e., healthy) knee tibial rotation and high function without causing stiffness is unknown. The purpose was to determine whether a ball-in-socket (B-in-S) medially conforming (MC) and flat lateral insert implanted with unrestricted kinematic alignment
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Unrestricted kinematic alignment corrects fixed flexion contracture in robotically aligned total knees without raising the joint line in extension J. Exp. Orthop. Pub Date : 2023-11-11 Elliot Sappey-Marinier, Stefano Bini
Mechanically Aligned Total Knee Arthroplasty (MA TKA) typically addresses fixed flexion contractures (FFC) by raising the joint line during extension. However, in unrestricted Kinematically Aligned TKA (KA TKA) utilizing a caliper-based resection technique, the joint line is not raised. This study aims to determine the efficacy of KA TKA in restoring full extension in patients with FFC without increasing
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Distal Kaplan fibers and anterolateral ligament injuries are associated with greater intra-articular internal tibial rotation in ACL-deficient knees based on magnetic resonance imaging J. Exp. Orthop. Pub Date : 2023-11-09 Luca Farinelli, Amit Meena, Bertrand Sonnery-Cottet, Thais Dutra Vieira, Charles Pioger, Sachin Tapasvi, Elisabeth Abermann, Christian Hoser, Christian Fink
The purpose of the present study was to assess the internal rotation of the tibia on Magnetic Resonance Imaging (MRI) in a series of consecutive athletes with Anterior cruciate Ligament (ACL) tears. Retrospective analysis of prospectively collected data was performed to include all consecutive patients who had undergone primary ACL reconstruction between January 2022 and June 2022. The angle between
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Intra-articular injections in sport-active patients with degenerative cartilage lesions or osteoarthritis of the knee: a systematic review J. Exp. Orthop. Pub Date : 2023-11-08 Luca De Marziani, Alessandro Sangiorgio, Alessandro Bensa, Angelo Boffa, Luca Andriolo, Giuseppe Filardo
The aim of this systematic review was to analyse the available clinical evidence on intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis (OA) in sport-active patients. A literature search was performed in July 2023 according to the PRISMA guidelines on three electronic databases (PubMed, Cochrane, Web of Science). Studies addressing intra-articular
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Changes in tibial cortical dimensions and density associated with long-term locking plate fixation in goats J. Exp. Orthop. Pub Date : 2023-11-07 Kristin M. Bowers, Lori D. Terrones, Xiaocun Sun, Rebecca Rifkin, Elizabeth Croy, Henry S. Adair, Pierre-Yves Mulon, Silke Hecht, David E. Anderson
Cortical porosis, secondary to either vascular injury or stress-shielding, is a comorbidity of fracture fixation using compression bone plating. Locking plate constructs have unique mechanics of load transmission and lack of reliance on contact pressures for fixation stability, so secondary cortical porosis adjacent to the plate has not been widely investigated. Therefore, this study aimed to assess
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Local adiposity may be a more reliable predictor for infection than body mass index following total knee arthroplasty: a systematic review J. Exp. Orthop. Pub Date : 2023-11-06 John J. Heifner, Philip A. Sakalian, Robert J. Rowland, Arturo Corces
Improved understanding of the factors that predispose TKA patients to infection has considerable economic and medical impact. BMI is commonly used as a proxy for obesity to determine the risk of postoperative infection. However, this metric appears to be fraught with inconsistency in this application. BMI is a simple calculation which provides general insight into body habitus. But it fails to account
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The ligamentum mucosum’s potential as a preventative structure in the development of knee osteoarthritis J. Exp. Orthop. Pub Date : 2023-11-03 Alexandra Martin, Kenneth Liu, Majid Alimohammadi
This paper aimed to identify whether the presence, type, and/or morphology of the ligamentum mucosum could play a role in the development of knee osteoarthritis. Since its microscopic structure is alike that of other knee ligaments, it was hypothesized that its presence could facilitate knee motion and stability, thus preventing or reducing the extent of knee osteoarthritis. Thirty three cadavers (a
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Increased ACL direct insertion coverage provided more positive biomechanical effects on graft and bone tunnel during knee flexion: a simulation study J. Exp. Orthop. Pub Date : 2023-10-28 Yang Xiao, Zhaoxin Liang, Shiwen Shen, Fei Liu, Hai Hu, Bin Chen
Flattened femoral tunnels were recently applied in anatomical single-bundle anterior cruciate ligament (ACL) reconstruction. Little is known about the biomechanical effect of such changes during knee flexion. The aim of the present simulation study was to assess the effect of altered ACL direct insertion coverage on the biomechanics of the graft and bone tunnel. Five finite element (FE) models, including
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Diminazene aceturate or losartan ameliorates the functional, radiological and histopathological alterations in knee osteoarthritis rodent model: repurposing of the ACE2/Ang1-7/MasR cascade J. Exp. Orthop. Pub Date : 2023-10-25 Yasser H. Habib, Eman Sheta, Mahmoud Khattab, Mennatallah A. Gowayed
Current therapies for osteoarthritis (OA) are limited to analgesics and anti-inflammatory drugs. Considering the importance of oxidative stress and inflammatory mediators in OA etiology, we tested the hypothesis that targeting the renin–angiotensin–aldosterone system (RAAS) can improve OA anomalies. Diminazene (DIZE), an activator of angiotensin-converting enzyme 2 and the angiotensin 2 type-1 receptor
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Low-intensity pulsed ultrasound irradiation attenuates collagen degradation of articular cartilage in early osteoarthritis-like model mice J. Exp. Orthop. Pub Date : 2023-10-23 Yoshitsugu Kojima, Takayuki Watanabe
Osteoarthritis (OA) is a combination of degeneration and destruction of articular cartilage due to mechanical stress, secondary synovitis, and bone remodelling. In recent years, early knee OA, a preliminary stage of structural failure in OA, has attracted attention as a potential target for therapy to prevent the onset of OA. Intra-articular administration of monoiodoacetic acid (MIA) induces OA-like
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Outcomes of management of primary benign aggressive or malignant bone tumors around the elbow by limb-salvage surgery J. Exp. Orthop. Pub Date : 2023-10-23 Walid Atef Ebeid, Ismail Tawfeek Badr, Mohamed Kamal Mesregah, Bahaa Zakarya Hasan
Bone tumors around the elbow are rare, with frequently delayed diagnosis. The current study aimed to assess the functional and oncological outcomes of limb salvage surgery for primary benign aggressive or malignant bone tumors around the elbow. We conducted a retrospective review of patients with primary aggressive benign and malignant bone tumors around the elbow treated with limb salvage surgery
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Specific types of femoral head fractures: be alert for pre-, intra-, and post-operative ipsilateral femoral neck fractures following fracture-dislocation of the femoral head J. Exp. Orthop. Pub Date : 2023-10-13 Shenghui Wu, Jiong Mei
Ipsilateral femoral head and neck fractures (iFHNFs) are rare types of fractures that confer extremely poor prognosis among femoral head fractures (FHFs). Owing to the rarity of FHFs, it is challenging to diagnose iFHNFs. In addition, the clinical features of iFHNF have not yet been comprehensively elucidated. Therefore, this retrospective study aimed to summarize and analyze the clinical characteristics
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Interference screws manufactured from magnesium display similar primary stability for soft tissue anterior cruciate ligament graft fixation compared to a biocomposite material – a biomechanical study J. Exp. Orthop. Pub Date : 2023-10-10 Adrian Deichsel, Johannes Glasbrenner, Michael J. Raschke, Matthias Klimek, Christian Peez, Thorben Briese, Elmar Herbst, Christoph Kittl
Biodegradable interference screws (IFS) can be manufactured from different biomaterials. Magnesium was previously shown to possess osteoinductive properties, making it a promising material to promote graft-bone healing in anterior cruciate ligament reconstruction (ACLR). The purpose of this study was to compare IFS made from magnesium to a contemporary biocomposite IFS. In a porcine model of ACL reconstruction
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Stem cells for the treatment of early to moderate osteoarthritis of the knee: a systematic review J. Exp. Orthop. Pub Date : 2023-10-07 Theofylaktos Kyriakidis, Charalampos Pitsilos, Myrto Iosifidou, Alexandros Tzaveas, Ioannis Gigis, Konstantinos Ditsios, Michael Iosifidis
Mesenchymal stem cells (MSCs) present a valuable treatment option for knee osteoarthritis with promising results. The purpose of the present study was to systematically review the clinical and functional outcomes following mesenchymal stem cell application focusing on early to moderate knee osteoarthritis. A systematic search was done using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses
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ESSKA consensus initiative: why, when and how? J. Exp. Orthop. Pub Date : 2023-10-06 Philippe Beaufils, David Dejour, Giuseppe Filardo, Joan Carles Monllau, Jacques Menetrey, Romain Seil, Roland Becker
The goal of a Consensus in clinical practice is to provide daily practitioners with evidence- based recommendations on data from the literature, clinical expertise and expectations of professionals and patients. In this context, a consensus aligns with the principles of evidence-based medicine in clinical practice and is consequently regarded as a scientific work of a certain level of evidence (LOE)
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Preoperative demographics and laboratory markers may be associated with early dislocation after total hip arthroplasty J. Exp. Orthop. Pub Date : 2023-10-06 Brandon E. Lung, Megan R. Donnelly, Kylie Callan, Maddison McLellan, Taha Taka, Russell N. Stitzlein, William C. McMaster, David H. So, Steven Yang
The purpose of this study was to identify modifiable medical comorbidities, laboratory markers and flaws in perioperative management that increase the risk of acute dislocation in total hip arthroplasty (THA) patients. All THA with primary indications of osteoarthritis from 2007 to 2020 were queried from the National Surgical Quality Improvement Program (NSQIP) database. Demographic data, preoperative
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Accelerated evidence synthesis in orthopaedics—the roles of natural language processing, expert annotation and large language models J. Exp. Orthop. Pub Date : 2023-09-28 Bálint Zsidai, Janina Kaarre, Ann-Sophie Hilkert, Eric Narup, Eric Hamrin Senorski, Alberto Grassi, Olufemi R. Ayeni, Volker Musahl, Christophe Ley, Elmar Herbst, Michael T. Hirschmann, Sebastian Kopf, Romain Seil, Thomas Tischer, Kristian Samuelsson, Robert Feldt
In an era of electronical medical records, rapidly expanding publication rates of medical knowledge, and large-scale registries, orthopaedics is in a dire need of innovative approaches to facilitate the adoption of the latest knowledge in clinical practice. While machine learning (ML) has been heralded as one solution to many research tasks hampered by previous technological limitations [12], there
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A novel minimally invasive and press-fit method for symphysiodesis — a biomechanical analysis J. Exp. Orthop. Pub Date : 2023-09-28 Tobias Fritz, Marcel Orth, Sascha J. Hopp, Jeremy Briem, Jill Hahner, David Osche, Tim Pohlemann, Antonius Pizanis
Does the cylindrical shaped bone block allow a stable construct for the arthrodesis of the pubic symphysis compared to a rectangular shaped bone block. The cylindrical shaped bone block stabilized by a 3.5 symphyseal plate is inferior to the stabilization with an internal fixator. This study analyzed the arthrodesis of the pubic symphysis on 24 synthetic pelvises, using a rectangular shaped bone block
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Mincing bovine articular cartilage with commercially available shavers reduces the viability of chondrocytes compared to scalpel mincing J. Exp. Orthop. Pub Date : 2023-09-28 Lukas B. Moser, Christoph Bauer, Alexander Otahal, Daniela Kern, Dietmar Dammerer, Thore Zantop, Stefan Nehrer
The study aimed to compare the effect of mincing bovine articular cartilage with different shaver blades on chondrocyte viability. Bovine articular cartilage was harvested either with a scalpel or with three different shaver blades (2.5 mm, 3.5 mm, or 4.2 mm) from a commercially available shaver. The cartilage harvested with a scalpel was then minced into fragments smaller than 1 mm3 with a scalpel
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Incidence, functional outcomes and cure rate of hematogenous infection in a 2,498 Total Knee Arthroplasties cohort J. Exp. Orthop. Pub Date : 2023-09-25 Daniel Pérez-Prieto, Albert Pardo, Albert Fontanellas, Joan Gómez-Junyent, Pedro Hinarejos, Joan-Carles Monllau
The primary aim of the present study is to report the late acute hematogenous (LAH) prosthetic joint infection (PJI) cure rate following Total knee arthroplasty (TKA) treated by means of debridement, antibiotics, and implant retention (DAIR) in a long-term follow-up. The secondary purpose is to report the functional outcomes at that follow-up and to compare them with a non-infected group. This study
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Shaping experimental orthopaedics J. Exp. Orthop. Pub Date : 2023-09-24 Henning Madry
The library will endure; it is the universe. As for us, everything has not been written; we are not turning into phantoms. We walk the corridors, searching the shelves and rearranging them, looking for lines of meaning amid leagues of cacophony and incoherence, reading the history of the past and our future, collecting our thoughts and collecting the thoughts of others, and every so often glimpsing
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It is time to target psychological readiness (or lack of readiness) in return to sports after Anterior Cruciate Ligament tears J. Exp. Orthop. Pub Date : 2023-09-20 Anne Gro Heyn Faleide, Eivind Inderhaug
Functional recovery has for long been the focus of rehabilitation after an Anterior Cruciate Ligament (ACL) injury. It is now increasingly recognized that more attention should be given to patients` mental recovery, their psychological readiness for returning to sport, after such an injury. Within this relatively new field of science, clinicians need clarity on when and how psychological factors should
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Significant correlations between postoperative outcomes and various limb and component alignment strategies in medial unicompartmental knee arthroplasty: a systematic review J. Exp. Orthop. Pub Date : 2023-09-18 Manuel-Paul Sava, Alexandra Leica, Isabel Scala, Johannes Beckmann, Michael T. Hirschmann
To investigate the correlation between postoperative limb/component alignments and clinical/functional outcomes following medial unicondylar knee arthroplasty (mUKA). Inclusion criteria included peer-reviewed English- or German-language publications assessing postoperative limb or implant alignment and clinical outcomes of mUKA. Methodological Index for Non-Randomized Studies (MINORS) was used to assess
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2-year results of middle-aged patients with two-compartment cartilage lesions in one knee treated with two patient specific metal implants J. Exp. Orthop. Pub Date : 2023-09-14 Daniel Aaron den Toom, Markus Rieke, Allaeldin Elbadawi, Clemens Kösters
Focal chondral lesions of the femur are currently treated with biological repair or arthroplasty. However, some patients are not suitable for either one due to lesion size, age, or prior biological treatment attempts. While singular patient-specific focal mini metal implants already showed good results, the outcomes of bicompartmental implantation of these implants have not been discussed in the literature
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Xenograft bone-patellar tendon-bone ACL reconstruction: a case series at 20-year follow-up as proof of principle J. Exp. Orthop. Pub Date : 2023-09-06 Kevin R. Stone, Ann W. Walgenbach, Thomas J. Turek, John V. Crues, Uri Galili
ACL reconstruction has a significant failure rate. To address the need for inexpensive strong tissue, a treatment process to “humanize” porcine tissue was developed and tested in primates and humans. This report describes the long-term outcomes from the first human clinical trial using a porcine xenograft ACL reconstruction device. The study was performed with Z-Lig™ xenograft ACL device in 2003 as
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Fracture healing in a polytrauma rat model is influenced by mtDNA:cGAS complex mediated pro-inflammation J. Exp. Orthop. Pub Date : 2023-09-01 Preeti J. Muire, Alicia L. Lofgren, Stefanie M. Shiels, Joseph C. Wenke
The mitochondrial DNA (mtDNA) activated cyclic guanosine monophosphate–adenosine monophosphate synthase—stimulator of interferon genes (cGAS-STING) signaling pathway is a key player in mediating immune responses in autoimmune disorders and cancer. However, its role in severe trauma associated fracture healing is unknown. This study investigated if the cGAS-STING signaling pathway contributes to delayed