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Is There Utility in Preoperative Testing of Hemoglobin Before Primary Cheiloplasty? Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-15 Aryan Shay, Megan Gaffey, Roger Roe, Alexa Robbins, Isabella Zaniletti, Adam Johnson, Larry Hartzell
ObjectiveTo examine whether a preoperative hemoglobin of less than 10 g/dL is associated with a higher rate of perioperative complications.DesignRetrospective review.SettingTertiary academic hospital at Arkansas Children's Hospital of Little Rock, Arkansas.PatientsA retrospective chart review evaluated patients undergoing primary cleft lip surgery from 2012 to 2017.InterventionsNo prospective intervention
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Diagnostic Potential of Complementation of MRI to Prenatal Ultrasound for Detecting Orofacial Clefts in High-Risk Fetuses: A Network Meta-Analysis Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-15 Jing Zhai, Shuyan You, Zhonghua Liang, Haihua Yu, Chengfeng Zhu, Lu Han
ObjectiveTo compare the complementation of magnetic resonance imaging (MRI) to prenatal ultrasound (US) with prenatal US alone in detecting orofacial clefts in high-risk fetuses.DesignA network meta-analysis.SettingLiterature retrieval in PubMed, EMBASE, and Cochrane library, and meta-analysis based on STATA 14.0.PatientsFetuses were at high-risk for orofacial clefts.InterventionsPrenatal US and the
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A 10-Year Nationwide Analysis of Risk Factors of Readmission and the Implications of Same-Day Discharge Following Velopharyngeal Insufficiency Correcting Surgery Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-15 Idean Roohani, Eloise Stanton, Collean Trotter, Dylan G. Choi, Sarah Alfeerawi, Pasha Shakoori, Ishani D. Premaratne, Aydin Hammoudeh, Artur Fahradyan, Mark M. Urata
ObjectiveTo investigate risk factors for readmission and the implications of same-day discharge for surgical management of velopharyngeal insufficiency (VPI).DesignRetrospective cohort.SettingMulti-institutional/national.Patients and ParticipantsPatients who underwent VPI-correcting surgery (n = 4479) were identified in the National Surgical Quality Improvement Program Pediatric database from 2012–2021
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Can MRI Replace Nasopharyngoscopy in the Evaluation of Velopharyngeal Insufficiency? Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-15 Jessica L. Williams, Jamie L. Perry, Taylor D. Snodgrass, Davinder J. Singh, M’hamed Temkit, Thomas J. Sitzman
ObjectiveTo investigate whether flexible nasopharyngoscopy, when performed in addition to magnetic resonance imaging (MRI), influences the type of surgery selected or success of surgery in patients with velopharyngeal insufficiency (VPI).DesignCohort study.SettingA metropolitan children's hospital.PatientsPatients with non-syndromic, repaired cleft palate presenting for management of VPI.InterventionsMRI
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Tranexamic Acid: Safeguarding Children with Craniosynostosis from Bleeding. A Review Article Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-14 Khildan Miftahul Firdaus, Lucky Andriyanto, Adil Jihad Muhammad, Tatang Bisri
Craniosynostosis is a congenital condition characterized by the premature closure of one or more sutures in the skull after birth, often necessitating urgent surgical intervention. Nevertheless, cranial vault reconstruction surgery can cause rapid and massive blood loss. This procedure requires a blood transfusion, which entails potential hazards. In addition, the hemostatic system in children differs
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Preoperative Velopharyngeal Closure Predicts Hypernasality Outcomes of Secondary Furlow Double-Opposing Z-Plasty Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-14 Kayla Prezelski, Carolyn Kim, Jeyna Perez, Cortney Vant Slot, Alex A. Kane, James R. Seaward
ObjectiveTo determine if preoperative velopharyngeal closure percentage (VCP) is predictive of successful Furlow double opposing Z-plasty (DOZP) and subsequently determine the optimal velopharyngeal closure cutoff for successful DOZP.DesignRetrospective studySettingTertiary academic centerPatients110 patients with repaired cleft lip and palate having hypernasality treated with DOZPInterventionsSpeech
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A Longitudinal Analysis of Pre- and Post-Operative Dysmorphology in Metopic Craniosynostosis Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-14 Justin W. Beiriger, Wenzheng Tao, Zhazira Irgebay, John Smetona, Lucas Dvoracek, Nicolás M. Kass, Angel Dixon, Casey Zhang, Meeti Mehta, Ross Whitaker, Jesse A. Goldstein
ObjectiveThe purpose of this study is to objectively quantify the degree of overcorrection in our current practice and to evaluate longitudinal morphological changes using CranioRateTM, a novel machine learning skull morphology assessment tool.DesignRetrospective cohort study across multiple time points.SettingTertiary care children's hospital.PatientsPatients with preoperative and postoperative CT
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Association of Commonly Prescribed Antepartum Medications and Incidence of Orofacial Clefting Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-07 Matteo Laspro, Hilliard T. Brydges, Alexandra N. Verzella, Jill Schechter, Andre Alcon, Ashley S. Roman, Roberto L. Flores
BackgroundPharmacologic agents are often used in the antepartum period, however, studies on their effect on fetal development are limited. Thus, this study aims to examine the effect of commonly prescribed antepartum medications on the development of orofacial clefting.MethodsUtilizing EPIC Cosmos deidentified data from approximately 180 US institutions was queried. Patients born between January 1
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Can Alveolar Bone Grafting Using Posterior Iliac Crest be a Day Surgery Procedure? Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-04 Alistair Varidel, Maria Ambrose, Nancy DiTullio, Taylor Fritschy, Bonnie L. Padwa, Cory M. Resnick
ObjectiveThe purpose of this study was to determine if patients undergoing alveolar bone grafting (ABG) can be discharged home on the day of surgery safely and with high satisfaction.DesignThis is a prospective cohort study of patients who underwent ABG over a 6-month period (August 2022 to February 2023). Medical records were reviewed, and postoperative surveys were provided to assess patient/family
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Psychosocial Status and Self-Perception in Patients with Cleft Lip and/or Palate Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-04 Lauren K Salinero, Dominic J. Romeo, Matthew E Pontell, Leigh Friedman, Vinayak S Ahluwalia, Connor S Wagner, Carlos E Barrero, Joseph Napoli, Oksana A Jackson, David W. Low, Scott P Bartlett, Jordan Swanson, Leanne Magee, Jesse A Taylor
ObjectiveTo describe how the psychosocial status of patients with cleft lip and/or palate (CL/P) relates to patient-reported outcomes (PROs).DesignCross-sectional retrospective chart review.SettingTertiary care pediatric hospital.Patients/ParticipantsPatients aged 8 to 29 years attending cleft team evaluations during a 1-year period.Main Outcome MeasuresCLEFT-Q.ResultsPatients (N = 158) with isolated
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Sociodemographic Factors Predict Long-Term Attrition from Multidisciplinary Cleft Clinic Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-01 Connor S Wagner, Sarah L Barnett, Dominic Romeo, Carrie Z Morales, Lauren K Salinero, Carlos E Barrero, Matthew E Pontell, Rachel A McKenna, Nancy Folsom, Jesse A Taylor, Jordan W Swanson
ObjectiveIdentify and describe factors associated with retention and attrition of patients during longitudinal follow-up at multidisciplinary cleft clinic.DesignRetrospective cohort study.SettingSingle, tertiary care center.Patients, ParticipantsPatients born between 1995 and 2007 with a diagnosis of cleft palate with or without cleft lip attending multidisciplinary cleft clinic.InterventionsNone tested
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Suprazygomatic Maxillary Nerve Block in Palatoplasty: A Retrospective Cohort Study of Perioperative Outcomes in Syndromic and Non-Syndromic Children Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-03-01 Krystof Stanek, Walid Alrayashi, Lisa Nussbaum, Ingrid M. Ganske, Carolyn R. Rogers-Vizena
ObjectiveThis study compares the impact of surgical site infiltration of local anesthesia alone to surgical site infiltration plus suprazygomatic maxillary nerve block (SMB) in non-syndromic and syndromic children undergoing primary palatoplasty.DesignRetrospective cohort study of intra- and post-operative outcomes and opioid utilization in children undergoing palatoplasty by a single surgeon.SettingUrban
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Correlation between Cleft Width and Adjacent Teeth Inclination in Patients with Unilateral Cleft Lip and Palate Using CBCT: A Retrospective Study Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-29 Reham Khaled Tayyar, Tarek Z. Khattab
ObjectivesTo evaluate buccolingual and mesiodistal inclination of cleft-adjacent maxillary permanent central incisors (U1) and canines (U3) in patients with unilateral cleft lip and palate (UCLP) in the late mixed dentition and to investigate the correlation between the alveolar cleft width and cleft-adjacent teeth inclination using cone beam computed tomography (CBCT).DesignObservational cross-sectional
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Stress and Coping Strategies in Malay Parents of Children with Cleft Lip and/or Palate Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-28 Bachok Norsa’adah, Che Ghazali Nurhazalini-Zayani, Abd Aziz Aniza, Abd Rahman Normastura, Abdullah Ahmad-Burhanudddin
ObjectiveThis study was aimed at describing the level of stress and types of coping strategies used among Malay parents of children with cleft lip and/or palate (CL/P).DesignCross-sectional study.SettingA dental clinic and a general hospital.ParticipantsParents (N = 84) whose children were less than 12 years old with CL/P.MethodsSocio-demographic data and clinical characteristics of CL/P were collected
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Two Chinese Patients of Auriculocondylar Syndrome 2: A Novel PLCB4 Splicing Variant and 5-Year Follow-up Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-28 Yunting Lin, Ye Zhang, Jian Ma, Shu Liu, Yongxi Liu, Chaoxiang Yang, Chunhua Zeng, Xianqiong Luo
ObjectiveAuriculocondylar syndrome (ARCND) is a set of rare craniofacial malformations characterized by variable micrognathia, ear malformations, and mandibular condyle hypoplasia, and other accompanying features with phenotypic complexity. ARCND2 caused by pathogenic variants in the PLCB4 gene is a very rare disease with less than 50 patients reported and only 36 different variants of the PLCB4 gene
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Cleft Laterality Dental Arch Relationship Outcomes for Children with Unilateral Cleft Lip and Palate in New Zealand Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-28 Peter V. Fowler, H. Keall, D. Kennedy, D. Healey, J.M.D. Thompson
ObjectivesTo investigate cleft laterality dental arch relationship outcomes of children with non-syndromic complete unilateral cleft lip and palate (UCLP) in New Zealand.DesignA retrospective nationwide study.SettingsVirtual 3D orthodontic study models collected prior to undertaking secondary alveolar bone grafting.ParticipantsA total of 104 patients with UCLP (L = 80: R = 24).Outcome measuresFour
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Three-dimensional Analysis of Maxillary Morphology in Infants with Unilateral Cleft Lip and Palate Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-28 Jie Zheng, Wenying Kuang, Shiyu Yuan, Hong He, Wenjun Yuan
ObjectiveTo three-dimensionally (3D) analyze the maxillary morphology of infants with unilateral cleft lip and palate (UCLP) and preliminarily classify the alveolar arch to assist in personalization of sequence therapy.DesignRetrospective study.SettingPatients with UCLP referred to outpatients’ clinic.Participants84 nonsyndromic infants with complete UCLP were recruited (58 boys, 26 girls, mean age
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A Case Series of Three Patients with Cleidocranial Dysplasia: Clinical Presentation and Diagnostic Considerations Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-28 Uğur Berber, Ülkü Gül Şıraz, Mustafa Yakubi, Ebru Gök, Leyla Kara, Aslihan Kiraz, Munis Dündar, Nihal Hatipoglu
Cleidocranial dysplasia (CCD) is a rare genetic condition that affects the bones and teeth. In our study, we presented three cases of CCD, including one with a new mutation and two with a family history. Case 1 had a unique heterozygous frameshift mutation (NM_001015051,c.762del, p.(Ser256Valfs*2)), while Case 2 and her brother (Case 3) had a common pathogenic missense mutation (NM_001015051,c.674G
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Facial Analysis of Patients with Unilateral or Bilateral Cleft Lip and Palate Using 3D Stereophotogrammetry Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-26 Vanessa Ota Nogueira, Maria Carolina Neves, Karin Neppelenbroek, Thaís Marchini Oliveira, Chiarella Sforza, Simone Soares
ObjectivesTo evaluate the quantitative values of linear and angular facial anthropometrics in patients with unilateral cleft lip and palate (UCLP) and compare them with those of patients with bilateral cleft lip and palate (BCLP) using three-dimensional (3D) facial imaging.DesignRetrospective, observational, and cross-sectional study.SettingHospital for Rehabilitation of Craniofacial Anomalies/USP
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Retrospective Cohort Studies in Craniofacial Outcomes Research: An Epidemiologist's Approach to Mitigating Bias Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-23 Sara Kinter, Joseph A. Delaney, Srinivas Susarla, Christy McKinney
Retrospective cohort studies, defined as a follow-up study in which outcome occurred prior to study onset, are common in craniofacial outcomes research and will continue to be prevalent given the increasing availability of secondary datasets and inherent prospective study limitations. However, if available data are not adequately measured, or necessary variables are absent, retrospective cohort studies
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Occlusal Outcomes in Non-Robin Sequence Patients with Isolated Cleft Palate Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-23 Catherine Beaumont, Audrey Bellerive, Anne-Sophie Julien, Jacques E. Leclerc
Objectives1. To assess the skeletal class occlusion and lateral cephalometry in children with isolated cleft palates (non-Robin sequence) and 2. to identify associations between these findings and pre-palatoplasty cleft palate measurements.Study designRetrospective cohort study.SettingNorth American Institutional Tertiary Paediatric Center.PatientsOur cleft database was reviewed, and patients were
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Presurgical Infant Orthopedic Videos on YouTube™: A Thematic Analysis of Caregiver Narratives Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-23 Raed Alrubaiaan, Bhavana Nair, Fatemeh Amir-Rad, May Aljanahi, Vijay Kumar S, Sabarinath Prasad
ObjectiveInformation regarding how caregivers cope when using presurgical infant orthopedic (PSIO) appliances is sparse. This study aimed to understand caregivers’ perspectives and experiences with contemporary PSIO treatment.DesignPSIO videos shared on the YouTube™ platform were used as the data source. Videos with caregivers were identified (n = 21) and portions with caregiver narratives were transcribed
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Overjet in Infants: A Cross-Sectional Study Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-23 Mohamed El-Rabbany, Ryan Shargo, Pat Ricalde
ObjectiveThe purpose of this study was to determine the normal ranges for overjet in healthy infants under 12 months of age.DesignA cross sectional study of consecutive patients below 12 months of age.SettingThe study was conducted at a private practice in Tampa, FL that specializes in pediatric craniomaxillofacial disorders.PatientsAll patients under the age 12 months were considered for entry into
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Parental Stress, Infant Feeding and Well-being in Families Affected by Cleft Lip and/or Cleft Palate: The Impact of Early Follow-up Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-22 Nina Ellefsen Lindberg, Nina Margrethe Kynø, Kristin Billaud Feragen, Are Hugo Pripp, Kim Alexander Tønseth
ObjectiveTo document the impact of early follow-up by specialized cleft nurses (SCNs) provided to families affected by cleft lip and/or palate (CL/P) and the status of parental stress, infant feeding and well-being.DesignProspective inclusion of a control group, which only received standard care, followed by an intervention group that also received early SCN follow-up.SettingThe cleft lip and palate
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Hearing Outcomes in Patients with Cleft Lip and Palate in a Resource Limited Setting Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-21 Kanachai Boonpiraks, Yanin Nawachartkosit, Nattayaporn Charunruengterakul, Dhave Setabutr
To compare hearing outcomes of early versus late tympanostomy tube insertion in patients with cleft lip and palate in a resource limited settingRetrospective cohort study.Conducted at Queen Sirikit National Institute of Child Health, a tertiary care hospital in Bangkok, Thailand.Included 76 patients under 18 with cleft anomalies undergoing tympanostomy tube insertion between January 2018 and July 2022
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Prospective Evaluation of Health-Related Quality-of-Life in Children with Craniosynostosis Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-21 Valeria Gamarra, Gregory D. Pearson, Annie Drapeau, Jonathan Pindrik, Canice E. Crerand, Ari N. Rabkin, Ibrahim Khansa
ObjectiveTo investigate health-related quality of life (HRQL) in children aged 2 to 7 years, who have undergone surgery for craniosynostosis.DesignCross-sectional survey.SettingA tertiary pediatric academic medical center.ParticipantsChildren with craniosynostosis who underwent surgical correction, and who were 2–7 years old at the time of the study. Children from families that did not speak English
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Weight Gain of Infants with Robin Sequence Treated Nonsurgically Using the Stanford Orthodontic Airway Plate (SOAP): 1-Year Follow-Up Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-19 HyeRan Choo, Alexis S. Davis, Lisa C. Bain, HyoWon Ahn
ObjectiveTo identify weight gain trends of infants with Robin sequence (RS) treated by the Stanford Orthodontic Airway Plate treatment (SOAP).DesignRetrospective longitudinal cohort study.SettingSingle tertiary referral hospital.PatientsEleven infants with RS treated with SOAP.InterventionsNonsurgical SOAP.Main Outcome MeasuresBody weight, Weight-for-age (WFA) Z-scores, and WFA percentiles at birth
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Online Resources for Robin Sequence; an Analysis of Readability Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-19 R. Browne, C.M. Hurley, S. Carr, C. de Blacam
The objective was to evaluate the readability of easily accessible parent-directed information concerning Robin Sequence (RS) online, compared to the American Medical Association (AMA)-recommended sixth grade (age 11-12) readability level.A Google search of the term “Pierre Robin Sequence information” was performed. The first ten websites were evaluated using six commonly used readability formulas
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Bilateral Cleft lip Simulation Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-14 Jonathan Zaga-Galante, Raymond Tse, Richard A Hopper, Anne Arnold, David M Fisher, Karen W Wong-Riff, Dale J Podolsky
ObjectiveTo evaluate the features, anatomic accuracy, and educational value of a high-fidelity bilateral cleft lip simulator.DesignEvaluation of the simulator by expert cleft surgeons after performing a simulated bilateral cleft lip repair.SettingThe simulator was evaluated by the surgeons during the Latin American Craniofacial Association meeting.ParticipantsEleven experienced cleft surgeons evaluated
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Validating the Modified Small Double Opposing Z-Plasty for Palatal Lengthening in Primary Palatoplasty Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-13 Rafael Denadai, Chi-Chin Lo, Hyung Joon Seo, Nobuhiro Sato, Dax Carlo Go Pascasio, Srinisha Murali, Junior Chun-Yu Tu, Pang-Yung Chou, Lun-Jou Lo
ObjectiveTo appraise the degree of intraoperative palatal lengthening with the modified Furlow small double-opposing Z-plasty (sDOZ).DesignRetrospective single-surgeon (R.D.) study.PatientsNonsyndromic children (n = 167) with Veau types I to IV cleft palates who underwent primary sDOZ palatoplasty.InterventionsIntraoperative measurements of palatal lengths and widths were collected using calipers,
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The Influence of Sidedness in Unilateral Cleft Lip and Palate on Mid Facial Growth at Five Years of Age Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-13 Matthew Fell, David Chong, Paras Parmar, Ting-Li Su, Lars Enocson, Bruce Richard
ObjectiveTo determine whether facial growth at five years is different for children with a left versus right sided cleft lip and palate.DesignRetrospective cohort study.SettingSeven UK regional cleft centres.PatientsPatients born between 2000-2014 with a complete unilateral cleft lip and palate (UCLP).Main Outcomes Measure5-Year-Old's Index scores.Results378 children were included. 256 (68%) had a
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Genetic Associations of Oral Clefts in Arabs Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-12 Lateefa Alkharafi, Saud Alhasawi, Hisham Burezq, Alhanouf Alduraie, Muneera Alhuwais, Fatema Aldoub, Maryam Alduwaisan, Sara Aldoseri, Hala Hamdan, Nada Abdelhafez, Ashraf Mokhtar, Fawzi Alqatami, Ahmad Al-Serri, James Hartsfield, Suzanne Al-Bustan
ObjectiveThis study aims to investigate genetic association between Non-syndromic Cleft lip with or without palate (NCLP) and 14 specific Single Nucleotide Polymorphism (SNPs) reported to be associated with NCLP from previous Genome Wide Association Studies (GWAS).DesignA prospective case-control study.SettingMinistry of Health (MOH) Cleft and Craniofacial Clinic and Kuwait University.Patients/ParticipantsOne
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Application of the MicroNAPS Classification for Robin Sequence Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-02 Cory M. Resnick, Eliot Katz, Alistair Varidel
ObjectiveThe only findings consistent among infants with Robin sequence (RS) are the presence of micrognathia, glossoptosis, and upper airway obstruction (UAO). Feeding and growth dysfunction are typical. The etiopathogenesis of these findings, however, is highly variable, ranging from sporadic to syndromic causes, with widely disparate levels of severity. This heterogeneity has created inconsistency
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Detecting Gene-Gene Interaction among DNA Repair Genes in Chinese non-Syndromic Cleft lip with or Without Palate Trios Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-02-02 Xi Chen, Zhibo Zhou, Yixin Li, Siyue Wang, Enci Xue, Xueheng Wang, Hexiang Peng, Meng Fan, Mengying Wang, Xueying Qin, Yiqun Wu, Jing Li, Hongping Zhu, Dafang Chen, Yonghua Hu, Terri H. Beaty, Tao Wu
ObjectiveThe objective of this study is to investigate the gene-gene interactions associated with NSCL/P among DNA repair genes.DesignThis study included 806 NSCL/P case-parent trios from China. Quality control process was conducted for genotyped single nucleotide polymorphisms (SNPs) located in six DNA repair genes ( ATR, ERCC4, RFC1, TYMS, XRCC1 and XRCC3). We tested gene-gene interactions with Cordell's
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12-Year Trends of Orofacial Clefts in the United States: Highlighting Racial/Ethnic Differences in Prevalence of Cleft Lip and Cleft Palate Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-31 Iulianna C. Taritsa, Joanna K. Ledwon, Anitesh Bajaj, Arun K. Gosain
ObjectiveDiscrepancies in prevalence among infants with orofacial clefts are public health research priorities. Our objective was to calculate updated estimated prevalence of orofacial clefts in the United States, with sub-analyses by racial/ethnic group.DesignThe National Birth Defect Prevention Network database was used to evaluate trends in cases with orofacial cleft in the United States from 2006
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Cortical Bone Thickness and Morphology at the Infrazygomatic Crest Area in Growing Thai Patients with UCLP: A CBCT Study Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-31 Ploypailin Phusantisampan, Marasri Chaiworawitkul
ObjectivesTo determine and compare buccal cortical bone thickness and morphology (in terms of shape and height) at the infrazygomatic (IZ) crest in growing Thai patients with unilateral cleft lip and palate (UCLP) using cone-beam computed tomography (CBCT) with the ultimate goal of identifying potential sites that are suitable for the placement of miniplates.DesignProspective study.SettlingInstitutional
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Maternal Exposure to Stress During Covid-19 and Non-Syndromic Orofacial Clefts: A Cohort Retrospective Study Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-19 Heba Jafar Sabbagh, Mona Talal AlSharif, Fatma Dawood Abdulhameed, Aziza Johar Aljohar, Reema Mahdi Alhussain, Sultan Musaad Alghamdi, Najla Sulaiman Alrejaye, Latifa Yousef AlGudaibi, Bahaudbdin Ibraheem Sallout, Badi Shoaib Albaqawi, Eman Abdulbaset Alnamnakani, Lougin Khalid Brekeit, Osama Adel Basri, Manal Ibrahim Almalik, Norah Suliman Al Soqih, Ali Bakr Alshaikh, Abdullah Jameel Aburiziza, Faisal
ObjectiveThe coronavirus (COVID-19) pandemic presents an opportunity to study stress's effect on the development of non-syndromic orofacial clefts (NSOFCs). This study was aimed at assessing maternal stress exposure during the pregestational to first trimester pregnancy periods and the development of NSOFCs during a year of the COVID-19 pandemic.DesignCohort study of infants with NSOFCs and controls
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Hospital Variation and Resource Use for Infants with Craniosynostosis Undergoing Open, Endoscopic, and Distraction Osteogenesis Surgical Techniques Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-19 Melissa D. Kanack, Mark R. Proctor, John G. Meara, Daniel M. Balkin, Jonathan Rodean, Isabel C. Stringfellow, Jay G. Berry
BackgroundCraniosynostosis is treated with endoscopic, open, and/or distraction surgical techniques. We assessed institutional variation in the use these techniques for craniosynostosis and compared hospital resource use.MethodsRetrospective analysis of 5249 infants age <18 months old undergoing surgical procedures for all types of craniosynostosis in 2016–2020 in 39 freestanding children's hospitals
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What Parents of Children Born with a Cleft Lip and/or Palate Want to Know About the Care for their Child Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-19 F.A.C.J. Heijsters, M.D. van Eick, F. van Nassau, M. Bouman, Corstiaan C. Breugem, M.C. de Bruijne, M.G. Mullender, J.P.W. Don Griot
ObjectiveAdequate health information that matches the needs of care recipients is a prerequisite for patient-centered care. To facilitate the provision of tailored and timely information, it isimportant to understand the information needs of parents of children and adolescents with cleft lip and/or palate (CL/P) themselves, and in addition they were asked how they experienced the provided care-related
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Validity of the Cleft Aesthetic Rating Scale Does Not Improve with Inclusion of Fixed Scores for Atypical Outcomes Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-19 Y. Vroom, N. S. S. Kornmann, D. G. M. Mosmuller, F. B. Niessen, J. P. W. Don Griot
ObjectiveThe Cleft Aesthetic Rating Scale (CARS) is a valid tool to assess the aesthetic outcome after unilateral cleft lip and palate (UCLP) repair. The goal of this study was to investigate whether the reliability of CARS increases by including fixed rates for atypical outcomes such as a smaller nostril, lower vermillion border or whistling deformity.Design197 patients with UCLP who underwent cleft
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Management of Velopharyngeal Dysfunction (VPD) Following Cleft Palate Repair: A Comprehensive Decision-Making Process Based on Severity and Structural Deficiencies Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-12 Syed Altaf Hussain, Charanya Vijayakumar, Subramaniyan Balasubramanian, Sara Rahavi-Ezabadi, Vishnu Sundar, Deborah Sybil, Zaid Hussain
ObjectiveTo describe a comprehensive decision-making process for surgical correction of structural Velopharyngeal Dysfunction (VPD) following cleft palate repair and evaluate its efficacy.DesignRetrospective study.SettingTertiary care hospital.Patients300 consecutive patients with unilateral or bilateral cleft lip and palate (CLP) or isolated cleft palate (CP) diagnosed with clinical VPD following
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The Use of Platelet Concentrates in the Reconstruction of the Alveolar Cleft Defect: A Systematic Review and Meta-Analysis Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-10 Mariana Vásquez-Álvarez, Qian Wang, Uriel Zapata
ObjectiveEvaluate quantitative and qualitative outputs when comparing the incidence of platelet concentrates (PCs) combined with autogenous bone grafts to an autograft control group for the reconstruction of alveolar cleft defects.DesignSystematic review and meta-analysis.Patients/ParticipantsRandomized and nonrandomized controlled clinical trials where PCs were used in the reconstruction of alveolar
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Impact of Neighborhood Deprivation and Social Vulnerability on Outcomes and Interventions in Patients with Cleft Palate Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-10 Kaamya Varagur, John Murphy, Gary B. Skolnick, Sybill D. Naidoo, Lynn M. Grames, Katherine A. Dunsky, Maithilee Menezes, Alison K. Snyder-Warwick, Kamlesh B. Patel
ObjectiveTo examine whether neighborhood disadvantage impacts length of follow-up, interventions, and outcomes for patients with cleft palate.DesignRetrospective cohort.SettingCleft Palate Craniofacial Institute Database at St. Louis Children's Hospital.Patients/ParticipantsPatients with cleft palate following in St. Louis Children's Hospital Cleft Palate Multidisciplinary Team Clinic.InterventionsPrimary
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Developmental Risk for Infants with Cleft Lip with or Without Cleft Palate Based on Caregiver-Proxy Reports Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-10 Kathleen A. Kapp-Simon, Meredith Albert, Todd C. Edwards, Salene M. Jones, Claudia Crilly Bellucci, Janine Rosenberg, Donald L. Patrick, Carrie L. Heike
Objectives(1) Assess caregiver-reported development in infants born with cleft lip ± alveolus (CL ± A) and cleft lip and palate (CLP); (2) determine factors associated with increased developmental risk; and (3) determine consistency of developmental risk before and after surgery for cleft lip.DesignProspective, longitudinal assessment of development. Time (T) 1, prior to lip closure; T2, 2 months post
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Helmet Therapy for the Management of Deformational Plagiocephaly in Pediatric Patients with Shunted Hydrocephalus Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-09 Emily A. Johnson, Gretchen M. Koller, Ryan Jafrani, Kamlesh Patel, Sybill Naidoo, Jennifer M. Strahle
ObjectiveTo evaluate the safety and efficacy of helmet therapy for deformational plagiocephaly in patients with shunted hydrocephalus.DesignRetrospective chart review.SettingInstitutional, tertiary-care hospital.PatientsAll patients at St. Louis Children's Hospital between 2014 and 2021 with shunted hydrocephalus who underwent helmet therapy for deformational plagiocephaly.InterventionsHelmet therapy
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Easing the Burden on Caregivers- Applications of Artificial Intelligence for Physicians and Caregivers of Children with Cleft Lip and Palate Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-05 Sara C Chaker, Ya-Ching Hung, Mariam Saad, Michael S Golinko, Izabela A Galdyn
ObjectiveMany caregivers of children with cleft lip and palate experience a high level of anxiety throughout their child's medical and surgical care. We aim to evaluate artificial intelligence (AI) as a tool to mitigate these feelings and can aid clinicians in the development of robust pediatric educational materials for caregivers and families.DesignThirteen of the most common postoperative questions
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Abbe Flap Division Before Two Weeks’ Time: Harmful or Advantageous? Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-03 John N. Muller, Allison Diaz, Roberto L. Flores, David A. Staffenberg
IntroductionThe Abbe flap is a standard intervention to treat upper lip deformities in patients with bilateral cleft lip. This two-stage procedure requires a 2 to 3-week period in which the superior and inferior lips remain connected. This study evaluates the safety of Abbe flap division and inset prior to 14 days’ time.Materials and MethodsA single institution, 8-year review of all patients with a
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Predicting Failure of Conservative Airway Management in Infants with Robin Sequence: The EARN Factors Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2024-01-03 Jennifer L. McGrath, Esperanza Mantilla-Rivas, Marudeen Aivaz, Monica Manrique, Md Sohel Rana, Hannah R. Crowder, Nathanael S. Oh, Gary F. Rogers, Albert K. Oh
ObjectiveEvaluate infants with Robin Sequence (RS) who were successfully treated with conservative airway measures alone vs. those who failed and eventually underwent surgical airway intervention after a protracted course of conservative management.DesignRetrospective review of prospectively gathered database.SettingLarge tertiary care institution.PatientsInfants diagnosed with RS (n = 122) who underwent
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Electromyographic Evaluation of Masticatory Muscle Activity in Individuals with and without Cleft Lip/Palate: A Systematic Review and Meta-analysis. Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-30 Hooman Shafaee,Arezoo Jahanbin,Mahsa Ghorbani,Asma Samadi,Erfan Bardideh
OBJECTIVE This study aims to systematically review and meta-analyze the electromyographic activity of masticatory muscles in cleft palate and non-cleft patients, and identify influencing factors. DESIGN Systematic Review and Meta-analysis. PATIENTS AND EXPOSURES Patients with cleft lip/ palate. COMPARISON Patients without CL/P. MAIN OUTCOME MEASURES Electrical activity of masseter and temporalis muscles
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Anatomical and Physiological Changes Following Primary Palatoplasty Using "The Buccal Flap Approach". Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-30 Abigail E Haenssler,Robert Mann,Imani R Gilbert,Taylor Snodgrass,Samuel Mann,Andy Kampfshulte,Jamie L Perry
OBJECTIVE The purpose of this study was to determine the anatomical differences among selected individuals with a cleft palate repaired using "The Buccal Flap Approach" during primary palatoplasty compared to aged-matched participants without cleft palate. DESIGN Observational, prospective. SETTING Two regional hospitals. PARTICIPANTS A total of 30 adult males consisting of 15 adults born with cleft
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Systematic Review and Meta-Analysis of the Index of Orthognathic Functional Treatment Need for Detecting Subjects with Great Need for Orthognathic Surgery. Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-30 Ali Borzabadi-Farahani
Index of Orthognathic Functional Treatment Need (IOFTN) Identifies patients with greatest need for orthoganthic surgery. This systematic review looks into the available evidence on prevalence of patients with great treatment need (IOFTN 4&5) who had orthognathic surgery in previous studies. Literature search of the major electronic databases was carried out for articles published between 2014 and September
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Modified Mucosal Reconstruction in Unilateral Complete Cleft of Lip and Primary Palate: Surgical Technique and Practical Strategies. Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-28 Rafael Denadai,Lun-Jou Lo
The nasal floor and intraoral lining reconstruction of unilateral complete cleft of lip and primary palate has sparsely been reported. Solution: This article combines the previously-described C-flap mucosal flap and inferior turbinate flap with the newly-described lateral nasal mucosal flap for the mucosal repair of this uncommon subtype of deformity. Valuable practical strategies are offered to optimize
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Standardization of Videorecorded Speech Samples for Children with Cleft Palate: Methods to Facilitate High-Quality Speech Outcomes Data Collection. Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-28 Adriane L Baylis,Caitlin E Cummings,Kari M Lien,Thomas J Sitzman,Richard E Kirschner,Kathy L Chapman,
BACKGROUND Collection of high-quality videorecorded speech samples is essential for speech outcomes research. SOLUTION Cleft palate team SLPs were trained to collect standard videorecorded speech samples in the clinic setting across 20 sites in North America. Standard training and equipment was provided. WHAT WE DID THAT IS NEW Quality management procedures were developed and utilized to verify video
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Interrater Reliability for Classifying Craniofacial Microsomia Severity: A Call for Objective Evaluation. Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-22 Elsa M Ronde,Jitske W Nolte,Alfred G Becking,Corstiaan C Breugem
OBJECTIVE The severity of craniofacial microsomia (CFM) is generally classified using the Orbit, Mandible, Ear, Soft tissue, Nerve (OMENS) classification score. The global assessment of the Phenotypic Assessment Tool for Craniofacial Microsomia (PAT-CFM), is a pictorial modification of the OMENS classification. The aim of this study was to assess the interrater reliability of the PAT-CFM global assessment
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Speech Outcomes of Buccal Myomucosal Flap Palatal Lengthening for Treatment of Velopharyngeal Insufficiency: Systematic Literature Review and Meta-Analysis. Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-22 Marina A Lentskevich,Alice Yau,Ariel E Figueroa,Kareem M Termanini,Arun K Gosain
OBJECTIVE Buccal myomucosal flaps (BMF) anatomically lengthen the palate in the treatment of velopharyngeal insufficiency (VPI). We systematically reviewed the existing literature on speech outcome of BMF palatal lengthening. DESIGN Three databases were used to identify studies of interest published in English. Studies that did not use standardized speech assessments were excluded. PRISMA checklist
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Current State of Clinical Trials Regarding Alveolar Bone Grafting. Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-21 Ahmad Al Malak,Yasmina El Masri,Mira Al Ziab,Maya Ghazi,Pascale Salameh
Alveolar ridge defects develop because of surgery, trauma, infection, or congenital malformations. Alveolar ridge defects can be resolved using an osseous replacement. The primary outcomes of osseous replacement are the maintenance of contour; the elimination of dead space, the reduction of postoperative infection; and the increase in bony and soft tissue healing. Recent research shows promising developments
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MSX1 Gene Polymorphisms in Patients with non-Syndromic Cleft lip and Palate: A Tertiary Care Centre Based Case-Control Study from Central Kerala. Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-15 Arun Jyothish,Alex George,Puthucode V Narayanan,Rajanikant Golgodu Krishnamurthy
OBJECTIVE The purpose of this study was to investigate the contribution of MSX1 gene polymorphisms to the risk of developing NSCLP. DESIGN Case-Control Study. SETTING A tertiary care centre. PATIENTS/PARTICIPANTS The sample consisted of 200 subjects (100 cases and 100 controls). INTERVENTIONS None. MAIN OUTCOME MEASURE(S) Genotyping was performed by restriction fragment length polymorphism. Allele
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Oral Cleft and Maternal History of Spontaneous Abortion: A Case-Control Study. Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-15 Maria Carolina de Moraes Pereira,Carolina Maia Silva,Thaís Bernardes de Queiroz,Lucimara Teixeira das Neves
To investigate and compare the occurrence of previous spontaneous abortion among mothers of children with nonsyndromic oral clefts (NSOC) and mothers of children without NSOC; to understand if previous spontaneous abortion could be a risk factor for the occurrence of NSOC in subsequent pregnancies. Case-control study. Nonsyndromic oral clefts is an important public health problem. In the context of
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The Utility of Pneumatic Cavity Volume in the Treatment of Exudative Otitis Media in Children with Cleft Palate. Cleft Palate-Craniofacial J. (IF 1.1) Pub Date : 2023-11-14 Koichiro Oyake,Yasunobu Amari,Aya Sakikawa,Izumi Sugitani,Yukiko Inoue,Tomotaka Shimura,Yojiro Kawamura,Hitome Kobayashi,Toshikazu Shimane,Sei Kobayashi
OBJECTIVE Measure the volume of air-containing space in children with cleft palate and assess age-related changes, recurrence rate of otitis media with effusion (OME) after tube removal, and temporal bone development trend based on time of tube placement. DESIGN Interventional prospective study. SETTING Cleft Lip and Palate Center at a Tertiary-level institution. PATIENTS/PARTICIPANTS One hundred sixty-eight