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Combined CPP-ACP and fluoride is not superior to fluoride alone in early carious lesions - a meta-analysis. Caries Res. (IF 4.2) Pub Date : 2023-10-26 Bianca Golzio Navarro Cavalcante,Alexander Schulze Wenning,Bence Szabó,Czumbela László Márk,Péter Hegyi,Judit Borbély,Orsolya Németh,Károly Bartha,Gábor Gerber,Gabor Varga
There is a growing need for effective methods in the management of early-stage carious lesions. Therefore, the aim of this study was to evaluate the effect of combined casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride on white spot lesions (WSLs) compared to fluoride-only interventions. This meta-analysis was performed according to PRISMA guidelines and registered in PROSPERO
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Film-forming polymers for inhibition of hydroxyapatite dissolution: a screening study. Caries Res. (IF 4.2) Pub Date : 2023-10-17 Letícia Oba Sakae,Taiana Paola Prado,Sávio José Cardoso Bezerra,Samira Helena Niemeyer,Alessandra Buhler Borges,Thiago Saads Carvalho,Tais Scaramucci
The aim of this study was to evaluate the effect of film-forming polymer solutions of different concentrations and pH values, either associated or not with sodium fluoride (F; 225 ppm F-), when applied during the initial stage of salivary pellicle formation, to prevent the dissolution of hydroxyapatite (HA), which was determined by the pH-stat method. Polyacrylic acid (PA), Chitosan, Sodium linear
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Shear bond strength of adhesives placed following selective removal of red-fluorescing carious dentine in vitro. Caries Res. (IF 4.2) Pub Date : 2023-10-05 Áine M Lennon,Nina Sophie Reich,Gerlinde Ferstl,Helga Ebensberger,Karl-Anton Hiller,Wolfgang Buchalla
Red-fluorescing dentine indicates bacterial contamination [Lennon et al.: Caries Res 2002;36:315-319]. We investigated effect of removal of red-fluorescent dentine-caries on shear-bond-strength and fracture-mode of 4 adhesive approaches. Sixty-five carious teeth and 50 non-carious controls were distributed into 4 groups: ClearfilTM self-etch (CSE), OptibondTM FL total-etch (OTE), ScotchbondTM Universal
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Fluoride Varnish in Dentistry: A Bibliometric Analysis of the 100 Most-Cited Papers. Caries Res. (IF 4.2) Pub Date : 2023-09-26 Mariana Perini Zendron,Aurélio de Oliveira Rocha,Melissa Santos da Silva Simões,Carla Miranda Santana,Michele Bolan,Mariane Cardoso
A highly cited paper is a milestone and might impact research and clinical practice. The present study analyzed the 100 most-cited papers on fluoride varnishes in dentistry. A search was performed on July 20, 2022, on the Web of Science Core Collection. Two independent researchers extracted the following data: number and citation density; year and journal of publication; study design; main topic; authors;
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The Global Prevalence and Severity of Dental Caries among Racially Minoritized Children: A Systematic Review and Meta-Analysis. Caries Res. (IF 4.2) Pub Date : 2023-09-21 Sonia Nath,Sneha Sethi,João L Bastos,Helena M Constante,Gloria Mejia,Dandara Haag,Kostas Kapellas,Lisa Jamieson
Racially minoritized children often bear a greater burden of dental caries, but the overall magnitude of racial gaps in oral health and their underlying factors are unknown. A systematic review and meta-analysis were conducted to fill these knowledge gaps. We compared racially minoritized (E) children aged 5-11 years (P) with same-age privileged groups (C) to determine the magnitude and correlates
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Interaction between Hexametaphosphate, Other Active Ingredients of Toothpastes, and Erosion-Abrasion in Enamel in vitro. Caries Res. (IF 4.2) Pub Date : 2023-09-19 Benedikt Luka,Andrea Duerrschnabel,Sina Neumaier,Nadine Schlueter,Kirstin Vach
Sodium hexametaphosphate (HMP) as toothpaste additive is claimed to reduce erosive tooth wear and to stabilize stannous ions. However, little is known about the impact of concentration and its interactions with fluoride (F) or stannous+fluoride ions (F/Sn) on enamel erosion and erosion-abrasion. In a 10 day cyclic in vitro erosion-abrasion model, 320 flat human enamel specimens were divided into ten
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Green Tea-Derived Catechins Suppress the Acid Productions of Streptococcus mutans and Enhance the Efficiency of Fluoride. Caries Res. (IF 4.2) Pub Date : 2023-09-12 Sili Han,Jumpei Washio,Yuki Abiko,Linglin Zhang,Nobuhiro Takahashi
Green tea-derived catechins, which can be divided into galloylated (epicatechin gallate: ECG, epigallocatechin gallate: EGCG) and non-galloylated (catechin: C, epicatechin: EC, epigallocatechin: EGC) catechins, are considered to be the main contributors to the caries control potential of green tea. In this study, we intended to compare the antimicrobial effects of these representative green tea-derived
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Assessing the Acceptability of Less Invasive Caries Removal Techniques for treating Deep Carious Lesions: A Conjoint Survey among Dentists Practicing in a Midwestern American State. Caries Res. (IF 4.2) Pub Date : 2023-09-12 Paula Ortega-Verdugo,John J Warren,Gary J Gaeth,Knute Carter,Elham Kateeb,Justine L Kolker,Dan M Shane
This study identified factors that influence dentists' decisions regarding less invasive caries removal techniques such as stepwise removal (SW) and selective removal (SE) using a marketing research technique, conjoint analysis. A survey was sent to 1,434 dentists practicing in Iowa. Dentists were randomly assigned to receive a questionnaire to rate the likelihood they would use either SW/SE in hypothetical
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Fluoride Exposure in Community Prevention Programmes for Oral Health Using Nail Clippings and Spot Urine Samples: A Systematic Review and Meta-Analysis. Caries Res. (IF 4.2) Pub Date : 2023-09-06 Fatemeh Eskandari,Elizabeth Adjoa Kumah,Liane Azevedo,John Stephenson,Sherley John,Fatemeh Vida Zohoori
Due to practical difficulties in quantifying fluoride exposure in populations, practical and accurate biomarkers can play a major role in the surveillance of fluoride. Among different fluoride biomarkers, spot urine and nail clippings have gained more attention due to their ease of acquisition. However, there is no robust consensus about the accuracy of these biomarkers for the estimation of fluoride
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Impact of Medical and Surgical Obesity Treatment on Dental Caries: A 2-Year Prospective Cohort Study. Caries Res. (IF 4.2) Pub Date : 2023-08-16 Negin Taghat,Karin Mossberg,Peter Lingström,Max Petzold,Anna-Lena Östberg
The objective was to study the long-term effects on oral health of bariatric surgery compared with medical treatment of obesity. Swedish females with morbid obesity (n = 66; 18-35 years at baseline) were followed prospectively from before obesity treatment until 2 years after treatment. The main response variable was dental caries registered according to the ICDAS-II system. Possible confounding factors
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Microcomputed Tomography Mineral Density Profile as Reference Standard for Early Carious Lesion Activity Assessment. Caries Res. (IF 4.2) Pub Date : 2023-08-16 Adam Michael Hoxie,Aline de Almeida Neves,Kevin Moss,Adalberto Bastos de Vasconcellos,Andrea Ferreira Zandona,Apoena Aguiar Ribeiro
Early caries diagnosis is crucial to treatment decisions in dentistry and requires identification of lesion activity: whether a carious lesion is active (progressively demineralizing) or arrested (progressively remineralizing). This study aimed to identify microtomographic (micro-CT) differences between active and arrested smooth surface enamel lesions, to quantify those micro-CT differences by creating
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Underlying dentin shadows (ICDAS 4) in occlusal surface of permanent teeth have low progression rate after 1-2 years. Caries Res. (IF 4.2) Pub Date : 2023-08-10 Patricia Kolling Marquezan,Luana Severo Alves,Letícia Donato Comim,Julio Eduardo do Amaral Zenkner
This prospective cohort study assessed the radiographic progression of underlying dentin shadows (UDS) on the occlusal surfaces of permanent posterior teeth of adolescents and young adults over 1-2 years and to identify possible risk factors. A total of 149 UDS lesions (from 101 individuals) were included at baseline. Each participant had to present at least one UDS to be considered eligible for the
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Selective Removal to Soft Dentine versus Full Pulpotomy for Management of Proximal Deep Carious Lesions: A Randomized Controlled Non-Inferiority Trial. Caries Res. (IF 4.2) Pub Date : 2023-08-08 Rechithra R,Wasim Wani,Sidhartha Sharma,Vijay Kumar,Amrita Chawla,Mani Kalaivani,Ajay Logani
The management of the deep carious lesion with reversible pulpitis is a dilemma for the dentist. The current study compared selective removal to soft dentine (SRSD) and full pulpotomy (FP) for treating proximal deep carious lesions in teeth with reversible pulpitis. Visual-tactile examination and bitewing radiographs were used to determine the depth of carious lesion, and American Association of Endodontists
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Immediate and Sustained Root Caries Prevention of Fluoride Varnish Combined with Toothpastes. Caries Res. (IF 4.2) Pub Date : 2023-08-07 Camila A Zamperini,Ana K Bedran-Russo
The aim of this study was to determine the immediate and sustained effect of a fluoride varnish and its combinations with toothpastes in preventing root caries development using a salivary microcosm in vitro model. Human root dentin specimens (n=150) were randomly divided into 5 experimental protocols (n=30): (1) Fluoride Varnish (V); (2) V followed by Paste One (V+PO); (3) V followed by Paste Plus
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Optimization of a validated protocol that determines bioavailable fluoride in toothpastes. Caries Res. (IF 4.2) Pub Date : 2023-08-01 Luis Fernando Bandeira Miranda,Cinthia Pereira Machado Tabchoury,Jaime Aparecido Cury
A validated protocol used to determine how much of total fluoride is bioavailable in toothpaste formulations was evaluated if it could be simplified regarding the following parameters: (i) concentration of the slurry (0.25-4%), (ii) centrifugation speed (1,000-12,000 g) and time (1-10 min) and (iii) incubation time for FPO32- ion hydrolysis and insoluble-F dissolution (15-60 min). Fresh and aged Na2FPO3/CaCO3
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Early counselling to improve oral health behavior in children with major congenital heart defects - a randomized controlled trial. Caries Res. (IF 4.2) Pub Date : 2023-07-13 Essi Karikoski,Taisto Sarkola,My Blomqvist
Maintaining optimal oral health behavior in children with a congenital heart defect (CHD) is important in managing the risk for caries development and infective endocarditis. The aim of this study was to evaluate the impact of an early and repeat oral health promotion intervention (OHPI) among of children with major CHD. Randomized controlled trial including 72 out of 91 children born in Finland 1
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Assessment of spin in the abstracts of randomized controlled trials in dental caries with statistically nonsignificant results for primary outcomes: A methodological study. Caries Res. (IF 4.2) Pub Date : 2023-06-15 Naichuan Su,Michiel W van der Linden,Clovis M Faggion,Geert J M G van der Heijden
The study aimed to assess the prevalence of spin in the titles and abstracts of RCTs in dental caries with statistically nonsignificant primary outcomes and to assess the risk indicators which may be associated with spin. Any original publication reporting a two-arm RCT in dental caries with clearly identified statistically nonsignificant primary outcomes published from January 1, 2015 until October
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Caries Experience in Elderly People Consuming a Milk-Based Drink Nutritional Supplement: A Cross-Sectional Study. Caries Res. (IF 4.2) Pub Date : 2023-06-14 Ramiro J Castro,Karla Gambetta-Tessini,Ignacio Clavijo,Rodrigo A Arthur,Marisa Maltz,Rodrigo A Giacaman
Nutritional supplements have been recommended to cope with malnutrition in elderly persons. In Chile, the Supplementary Nutrition Program for the Elderly (PACAM, for its Spanish acronym) consists in a monthly distribution of a low-fat-milk-based drink that contains 8% sucrose. The aim of this study was to determine whether older persons consuming the milk-based drink have a higher caries experience
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Reacting, Sharing, and Commenting: How Much Facebook Users are Interacting with Dental Caries-related Posts Containing Misinformation? Caries Res. (IF 4.2) Pub Date : 2023-05-23 Mariana Olimpio Dos Santos Remiro,Olivia Santana Jorge,Matheus Lotto,Natalino Lourenço Neto,Maria Aparecida Andrade Moreira Machado,Thiago Cruvinel
Recent studies have been concerned about the vast amount of misinformation detected on social media that directly hampers the prevention and control of chronic diseases. Based on these facts, the aim of this study was to identify and characterize misinformation about dental caries-related content found on Facebook, regarding the predictive factors of user interaction with posts. Then, CrowdTangle retrieved
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Differential Unmet Needs and Experience of Restorative Dental Care in Trajectories of Dental Caries Experience: A Birth Cohort Study. Caries Res. (IF 4.2) Pub Date : 2023-05-22 Begoña Ruiz,Jonathan M Broadbent,W Murray Thomson,Sandhya Ramrakha,Chuen Lin Hong,Richie Poulton
Dental caries is a chronic and cumulative disease but little has been reported on the continuity of the disease and its treatment through life. Group-based multi-trajectory modeling was used to identify developmental trajectories of untreated carious tooth surfaces (DS), restored tooth surfaces (FS), and teeth extracted due to caries (MT) from ages 9 to 45 years in a New Zealand longitudinal birth
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Enamel Fluoride Uptake Determined Using the Microbiopsy Technique and Time-of-Flight Secondary Ion Mass Spectrometry: A Pilot Study. Caries Res. (IF 4.2) Pub Date : 2023-05-10 Nicole Michler,Maria Morawietz,Stephan Gierth,Frank Lippert,Andreas Kiesow
This study evaluated the suitability of time-of-flight secondary ion mass spectrometry (ToF-SIMS) to assess enamel fluoride uptake (EFU) in comparison with the microbiopsy technique. Enamel specimens were exposed to equimolar solutions of fluoride prepared from sodium fluoride (NaF), stannous fluoride (SnF2), or amine fluoride (AmF). EFU was quantified by both techniques on the same specimens. EFU
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A bibliometric analysis of the top 100 most-cited papers concerning dental fluorosis Caries Res. (IF 4.2) Pub Date : 2023-04-26 Michely Cristina Goebel, Aurélio de Oliveira Rocha, Pablo Silveira Santos, Michele Bolan, Paulo Antônio Martins-Júnior, Carla Miranda Santana, MARIANE CARDOSO
A high number of citations can indicate the potential of any specific paper to influence other research and generate changes in clinical practice. Analyzing the most-cited papers in a certain scientific field may assist researchers to identify the influential papers as well their main characteristics. The present study aimed to analyze the 100 most-cited papers concerning dental fluorosis (DF) through
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Is patient’s caries activity associated with caries increment among adolescents, regardless of caries experience? Caries Res. (IF 4.2) Pub Date : 2023-04-19 Carolina Doege Brusius, Luana Severo Alves, Marisa Maltz
This 2.5-year cohort study investigated whether patient’s caries activity is independently associated with caries increment among adolescents, regardless of previous caries experience, in a sample of 801 adolescents from South Brazil. Caries examination was performed at baseline (12y) and at follow-up (14–15y). Caries activity was significantly associated with caries increment even after adjustment
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Effect of CPP-ACP added to Milk, Chewing Gum and Candy on Dental Caries: a Systematic Review Caries Res. (IF 4.2) Pub Date : 2023-04-13 Rodrigo A. Giacaman, Catalina A Maturana, José Molina, Catherine M.C. Volgenant, Constanza E. Fernández
Casein is one of the most studied proteins with activity against dental caries. In particular, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) has shown promising remineralizing properties. In vivo evidence on the anticaries potential of CPP-ACP added to foodstuffs is elusive, nonetheless. Hence, this systematic review aimed at determining whether the use of CPP-ACP added to foodstuffs
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Cost-effectiveness of pit and fissure sealing at schools for caries prevention in China: A Markov modeling analysis Caries Res. (IF 4.2) Pub Date : 2023-03-30 Liangru Zhou, Yi Li, Bingjie Liu, Mingsi Wang, Chengyao Sun, Xin Zhang, Guoxiang Liu, NOVIKOVA SIUZANNA
The World Health Organization states that the application of pit and fissure sealants (PFS) is an effective way to prevent dental caries. Estimates of potential health and economic impacts of PFS upon school-age children provide crucial evidence to support the extension of PFS coverage to all target populations. The China Children's Oral Disease Comprehensive Intervention Project was launched in 2009
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The impact of socio-environmental, individual and biologic factors on oral health-related quality of life among preschool children: a cohort study with 3-year follow-up Caries Res. (IF 4.2) Pub Date : 2023-03-08 Izabella Barbosa Fernandes, Joana Ramos Jorge, Priscila Seixas Mourão, Angélica Beatriz Rodrigues, Valéria Silveira Coelho, Mario Vianna Vettore, Maria Letícia Ramos-Jorge
This study assessed impact of socio-environmental, individual and biologic factors on the worsening and severe worsening of oral health-related quality of life (OHRQoL) among preschoolers and their families. A cohort study was conducted in Diamantina, Brazil, with 151 children between one and three years of age and their mothers, who were evaluated at baseline (2014) and re-evaluated after three years
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Three Dimensional Assessment of Radiographic Changes after Indirect Pulp Capping using Silver Diamine Fluoride with or without Potassium Iodide in Young Permanent Teeth (12-month RCT) Caries Res. (IF 4.2) Pub Date : 2023-03-06 Marwa Mohamed Ahmed Lotfy Baraka, Lucia Cevidanes, Magda Tekeya, Niveen Bakry, Antonio Ruellas, Tatiana Botero, Erika Benavides, Margherita Fontana
The aim was to have a three-dimensional evaluation of radiographic changes after indirect pulp capping (IPC) with silver diamine fluoride (SDF) with or without potassium iodide (KI) and resin modified glass ionomer cement (RMGIC) in deep carious young permanent molars using cone beam computed tomography (CBCT). 108 first permanent molars with deep occlusal cavitated caries lesions, in forty-nine 6–9-year-old
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Psychometric properties of food frequency questionnaires used in dentistry: a systematic review Caries Res. (IF 4.2) Pub Date : 2023-03-01 Caroline Souza dos Santos, Saulo Vinicius da Rosa, Samuel Jorge Moysés, Rodrigo Nunes Rached, Marcia Helena Baldani, Renata Iani Werneck, Gil Guilherme Gasparello, Juliana Schaia Rocha
The objective of this systematic review was to analyze the quality of the food frequency instruments/scales used in dentistry while considering their psychometric properties. The databases consulted were PubMed (07/08/2020), Scopus (08/27/2020), Web of Science (08/27/2020), Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Dentistry and Oral Sciences Source (via EBSCO) (28/ 08/2020
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Effects of Cathepsin K Inhibitors on Dentin Erosion: An In Vitro Study Caries Res. (IF 4.2) Pub Date : 2023-02-17 Yi-ying Chen, Xiu-jiao Lin, Zhi-cen Lu, Annette Wiegand, Hao Yu
Cathepsin K (catK) modulates the degradation of dentin collagen. This study aimed to evaluate the effects of catK inhibitors on dentin erosion. Dentin beams were eroded (4 times/d for 5 d) and immersed in deionized water (negative control), 0.1 M NaCl, 0.3 M NaCl, 0.5 M NaCl, or 1 μM odanacatib (each n = 16) for 30 min after each erosive challenge. Erosive dentin loss (EDL) and demineralized organic
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Primary Dentition caries patterns as predictors of permanent dentition caries: a prospective cohort study Caries Res. (IF 4.2) Pub Date : 2023-02-13 Carlos Alberto Feldens, Vanessa Simas Braga, Paulo Floriani Kramer, Márcia Regina Vítolo, Priscila Humbert Rodrigues, Elisa Maria Rosa de Barros Coelho, Benjamin W. Chaffee
The aims of this study were to estimate the risk of caries in the permanent teeth at 12 years of age and to describe the diagnostic accuracy of caries patterns in the primary dentition at age 4 years to predict caries at age 12 years. A prospective cohort study followed children from birth to age 12 years in the city of São Leopoldo, Brazil. Sociodemographic variables were collected at birth and dental
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Secondary caries detection and treatment decision according to two criteria and the impact of three-dimensional intraoral scanner on gap evaluation Caries Res. (IF 4.2) Pub Date : 2023-02-08 Bruna Lorena Pereira Moro, Stavroula Michou, Maximiliano Sérgio Cenci, Fausto Medeiros Mendes, Kim Rud Ekstrand
This study aimed to evaluate the in vitro performance in detecting caries around composite restorations in permanent posterior teeth and the impact of treatment decisions of two visual criteria: International Dental Federation (FDI) criteria and the Caries Associated with Restorations and Sealants (CARS) system. The correlation among secondary caries and the presence of gap measured with a three-dimensional
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OXIS contacts and approximal caries in preschool children- A prospective cohort study Caries Res. (IF 4.2) Pub Date : 2023-01-23 M Kirthiga, M.S. Muthu, Gurusamy Kayalvizhi, Vijay Prakash Mathur, Naveenkumar Jayakumar, R Praveen
The present prospective cohort study was conducted to evaluate the susceptibility of OXIS contact areas namely O (open type), X (point type), I (straight type) and S (curved type) in the development of approximal caries. We conducted this study among 953 school children with 3812 contacts in Puducherry, India. At baseline, the contacts were assessed in accordance with OXIS criteria. At the end of 12
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Early sugar introduction associated with early childhood caries occurrence Caries Res. (IF 4.2) Pub Date : 2023-01-20 Mariana Silveira Echeverria, Helena Silveira Schuch, Maximiliano Sérgio Cenci, Janaina Vieira dos Santos Motta, Andrea Damaso Bertoldi, Marcos Britto Correa, Marie-Charlotte D.N.J.M. Huysmans, Flávio Fernando Demarco
Consensus has yet to be reached on the impact of early sugar introduction on early childhood dental caries (ECC). This study aimed to evaluate the association between the time of introduction of sugar in the infant’s diet and ECC at 48 months, using data from the 2015 Pelotas Birth Cohort Study. This Cohort comprises 4,275 children. At 48 months, 3,654 (91.1%) children had their oral health clinically
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The role of oral nitrate-reducing bacteria in the prevention of caries: A review related to caries and nitrate metabolism Caries Res. (IF 4.2) Pub Date : 2023-01-17
Circulating nitrate is actively absorbed by salivary glands and secreted into the oral cavity, where it is reduced to nitrite by oral nitrate-reducing bacteria. This process has previously been considered harmful because nitrate and nitrite can promote the formation of potentially carcinogenic N-nitrosamines. However, recent studies have shown that nitrate may have other physiological functions, and
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Dentine mineral changes induced by polyalkenoate cements after different selective caries removal techniques: An in vitro study Caries Res. (IF 4.2) Pub Date : 2023-01-14 Paula Maciel Pires, Amanda Monteiro, Paula Helena de Accioly Costa, Aline Saddock Silva, Ricardo Tadeu Lopes, Kumiko Yoshihara, Salvatore Sauro, Aline de Almeida Neves
This study aimed at evaluating the mineral variation induced by polyalkenoate cements in residual dentine after different caries removal methods. Ten extracted sound molars were selected, and five cavities were prepared on the occlusal surface of each specimen. Carious lesions were generated using a microbial protocol, while the caries removal was performed using bur, hand excavator or two papain-based
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A bibliometric analysis of studies on root caries Caries Res. (IF 4.2) Pub Date : 2023-01-12 Mengzhen Ji, Di Fu, Ga Liao, Ling Zou
This study aimed to review the current state of the root caries field, explore the current hot topic, and anticipate future research frontiers. The Web of Science Core Collections (WoSCC) was searched to acquire publications that were relevant to root caries from 1992 to 2021. After retrieval and manual screening, the co-occurrence and co-operation analysis of keywords and countries/institutions/authors
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Solutions containing a statherin-derived peptide reduce enamel erosion in vitro Caries Res. (IF 4.2) Pub Date : 2023-01-11 Fabiana Navas Reis, Monique Malta Francese, Natara Dias Gomes da Silva, Vinícius Taioqui Pelá, João Victor Frazão Câmara, Juliana Sanches Trevizol, Heitor Marques Honorio, Edson Crusca, Reinaldo Marchetto, Marília Afonso Rabelo Buzalaf
The effect of solutions containing a statherin-derived peptide (Stn15pSpS) on the protection against enamel erosion in vitro was evaluated. Bovine enamel specimens were divided into 4 groups (n = 15/group): 1) Deionized water (negative control), 2) Elmex Erosion Protection™ (positive control), 3) 1.88 × 10-5 M Stn15pSpS and 4) 3.76 × 10-5 M Stn15pSpS. The solutions were applied on the specimens for
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Association of locus Xq26.1 – 27.3 with Erosive Tooth Wear Phenotypes in a Group of Adolescents Caries Res. (IF 4.2) Pub Date : 2023-01-10 Aida Mulic, Alexandre R. Vieira, Mariana Bezamat , Jenny Bogstad Sovik, Amer Sehic, Amela Tulek
Erosive tooth wear is a multifactorial condition of an increasing prevalence. There is a need for discovering individual genetic predisposition for the development of this condition. Considering that the chromosome X locus was shown to be associated with dental caries, the aim of the present study was to look for the association between this locus and erosive tooth wear when dietary habits are considered
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The 20-year trends in caries and associated determinants among adults in “post-Soviet” Lithuania: repeated cross-sectional studies Caries Res. (IF 4.2) Pub Date : 2023-01-10 Lina Stangvaltaite-Mouhat, Jolanta Aleksejūnienė, Ruta Bendinskaite, Ibrahimu Mdala, Indre Stankeviciene, Alina Puriene, Rasa Skudutyte-Rysstad
Aim. To examine the 20-year trend in dental caries and associated determinants among adults in Lithuania after the country restored its independence. Material and methods. Data from two cross-sectional national surveys included samples of 35-44-year-olds (adults) and 65-74-year-olds (early elderly). The 1997/1998 survey (first survey) recruited a stratified random sample of 570 individuals from 10
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Factors Related to Early Childhood Caries in 17- to 23-Month-Old Children in Aichi Prefecture, Japan: A Cross-Sectional Study Caries Res. (IF 4.2) Pub Date : 2023-01-10 Madoka Chiba, Hiroko Hashimoto, Toshiya Nonoyama, Hisanao Kito, Chieko Oguri, Yoshihiro Shimazaki
Dental caries is the most prevalent of chronic oral conditions. We investigated child and parental factors associated with early childhood caries (ECC) in 17- to 23-month-old children in Aichi Prefecture, Japan. Of the 61,714 children who underwent a health examination at 18 months of age, 54,206 (27,860 males, 26,346 females) were included in the analysis. The parents of the children completed a self-administered
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Did the use of minimum interventions for caries management change during the COVID-19 pandemic? A cross-sectional study Caries Res. (IF 4.2) Pub Date : 2023-01-09
Aim: to evaluate changes in the frequency of use of minimum interventions (MI) techniques for caries management during the COVID-19 pandemic. Materials and Methods: a questionnaire was applied through the SurveyMonkey™ platform to evaluate changes in the dentist’s frequency of use of non-invasive, micro-invasive, minimally invasive, and mixed interventions, non-aerosol, or aerosol productive, to manage
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Did the Use of Minimum Interventions for Caries Management Change during the COVID-19 Pandemic? A Cross-Sectional Study. Caries Res. (IF 4.2) Pub Date : 2023-01-09 Tainá Fontes de Souza,Mariana Leonel Martins,Lucas Alves Jural,Isadora Passos Maciel,Marcela Baraúna Magno,Raildo da Silva Coqueiro,Matheus Melo Pithon,Soraya Coelho Leal,Andréa Fonseca-Gonçalves,Lucianne Cople Maia
The aim of this study was to evaluate changes in the frequency of use of minimum intervention (MI) techniques for caries management during the COVID-19 pandemic. A questionnaire was applied through the SurveyMonkeyTM platform to evaluate changes in the dentist's frequency of use of noninvasive, microinvasive, minimally invasive, and mixed interventions, nonaerosol or aerosol productive, to manage dental
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New Theory Illustrates the Formation of Enamel Cup-Shaped Lesions on Occlusal Surfaces Caries Res. (IF 4.2) Pub Date : 2022-12-29 Frederico Barbosa de Sousa, Anderson Takeo Hara
We propose a new theory for enamel cupping lesions formation. At early stages, naturally-formed cupping lesions showed increased porosity at two structural prismatic traits: the central cone extending into the enamel-dentine junction and the type-I Hunther-Schreger bands (HSB), suggesting them to be the main drivers for cupping lesion formation and development. In addition, these lesions were circumscribed
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Accuracy of two visual criteria for the assessment of caries around restorations: a delayed-type cross-sectional study Caries Res. (IF 4.2) Pub Date : 2022-12-22 Juliana Lays Stolfo Uehara, Cácia Signori, Vitor Henrique Digmayer Romero, Fausto Medeiros Mendes, Maximiliano Sérgio Cenci
The aim of this study was to compare the performance of two visual criteria used for the detection of caries around restorations in permanent teeth. In this delayed-type cross-sectional study, the study sample was randomly allocated to one of two visual criteria for the assessment of restorations, as follows: a) FDI criteria (International Dental Federation; considers marginal staining, marginal adaptation
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Association between Carbonic Anhydrase VI (CA VI) gene copy number and dental caries experience Caries Res. (IF 4.2) Pub Date : 2022-12-20 Rania Al-Mahdi, Lina Stangvaltaite-Mouhat, Jolanta Aleksejūnienė, Indre Stankeviciene, Berit Tommeras, Alina Puriene, Mohammed Al-Haroni
The current study examined the association between the carbonic anhydrase VI (CA VI) copy number variations (CNVs) and dental caries experience in adults. In total, 202 of 35-72 years old subjects participating in the Lithuanian National Oral Health Survey (LNOHS) agreed to provide saliva samples, thus their data were included in the current study. Information about sociodemographic, environmental
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Fluorescence spectroscopy shows porphyrins produced by cultured oral bacteria differ depending on composition of growth media. Caries Res. (IF 4.2) Pub Date : 2022-12-16 Áine M Lennon, Leonora Brune, Simone Techert, Wolfgang Buchalla
Red fluorophores synthesized by oral bacteria are important for fluorescence-based diagnosis and treatment because they are used as markers for bacterially infected tissue, mature plaque or calculus. A range of porphyrins has been identified as the source of this fluorescence in carious tissue. It is not clear which of these porphyrins are produced by individual oral bacteria or whether this ability
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Ability of a blue hemoglobin-based liquid as a novel technology to stain initial enamel demineralization – A proof-of-concept in-vitro study Caries Res. (IF 4.2) Pub Date : 2022-11-30 Anahita Jablonski-Momeni, Mara Müller, Heike Korbmacher-Steiner, Peter Bottenberg
During orthodontic treatment enamel demineralization can occur. Its early detection is the basis for efficient preventive measures to arrest or remineralize lesions. In the present study, the application of a novel blue hemoglobin-based liquid (BlueCheck) was evaluated as proof of concept for detection of on artificially demineralized smooth surfaces. 60 samples form extracted human posterior teeth
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Impacts of the COVID-19 pandemic exposure on child dental caries: Difference-in-differences analysis Caries Res. (IF 4.2) Pub Date : 2022-11-28 Yusuke Matsuyama, Aya Isumi, Satomi Doi, Takeo Fujiwara
The impact of the coronavirus disease 2019 (COVID-19) pandemic on dental caries is unknown. We investigated the effect of the pandemic on child dental caries in Japan by comparing the increase in dental caries from fourth to sixth grade between two cohorts, COVID-19 exposed cohort, and COVID-19 unexposed cohort, using difference-in-difference analysis. A longitudinal data that followed elementary school
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Association between level of parental oral health literacy and the rational use of fluoride for children 0 to 4 years of age after instruction: intervention trial Caries Res. (IF 4.2) Pub Date : 2022-11-16 Sara Oliveira Lisboa, Cristiane Meira Assunção, Clarissa Lopes Drumond, Júnia Maria Cheib Serra-Negra, Marcia Gomes Penido Machado, Saul Martins Paiva, Fernanda de Morais Ferreira
An inadequate level of oral health literacy (OHL) can hinder the understanding of dental information, which can have a negative impact on health promotion actions, such as the rational use of fluoride. The aims of the present study were: 1) to look for association between parents/guardians´ OHL and the amount of fluoride toothpaste used for children from zero to four years of age; 2) to compare the
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Combined treatment with fluoride and antimicrobial peptide GH12 efficiently controls caries in vitro and in vivo Caries Res. (IF 4.2) Pub Date : 2022-11-15 Yufei Wang, Yuhao Zeng, Zening Feng, Zhongxu Li, Xuelian Jiang, Sili Han, Jumpei Washio, Nobuhiro Takahashi, Linglin Zhang
Combining fluoride and antimicrobial agents enhances regulation of acid and exopolysaccharide production by biofilms. The combination also weakens the acidogenic and aciduric bacteria that contribute to caries, achieving stronger caries-controlling effects with lower concentrations of fluoride. In previous studies, antimicrobial peptide GH12 has been shown to inhibit lactic acid and exopolysaccharide
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Changes in management preference of deep carious lesions and exposed pulps: questionnaire studies with a 10-year interval among dentists in Lithuania Caries Res. (IF 4.2) Pub Date : 2022-11-15 Lina Stangvaltaite-Mouhat, Indre Stankeviciene, Vilma Brukiene, Alina Puriene, Sergei N Drachev
We aimed to investigate changes in management preferences for deep carious lesions and pulps exposed during carious tissue removal that occurred during the last 10 years and identify associated dentists’ background factors. The data was collected among dentists registered with the Lithuanian Dental Chamber at two time points using a similar questionnaire. In 2011, 400 randomly selected dentists received
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Acknowledgement of Financial Support Caries Res. (IF 4.2) Pub Date : 2022-11-03
Caries Res 2022;56:382
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Diagnosis of interproximal caries lesions in bitewing radiographs using a deep convolutional neural network-based software. Caries Res. (IF 4.2) Pub Date : 2022-11-01 Ángel García-Cañas, Mónica Bonfanti-Gris, Sergio Paraíso-Medina, Francisco Martínez-Rus, Guillermo Pradíes
The aim of this study was to evaluate the diagnostic reliability of a web-based artificial intelligence program for the detection of interproximal caries in bitewing radiographs. Three hundred bitewing radiographs of patients were subjected to the evaluation of a convolutional neural network. First, the images were visually evaluated by a previously trained and calibrated operator with radiodiagnosis
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Improved surface layer erosion of pit and fissure caries lesions in preparation for resin infiltration Caries Res. (IF 4.2) Pub Date : 2022-10-28 Hendrik Meyer-Lueckel, Corina Moser, Richard Johannes Wierichs, Julian Lausch
The penetration of a low-viscosity resin (infiltrant) into caries lesions depends on the erosion of the relatively impermeable surface layer (SL) that covers the lesion body. The present study aimed to evaluate the effect of different abrasive pretreatments on erosion of the surface layer and on penetration of an infiltrant into occlusal caries lesions simultaneously. Sixty extracted human molars showing
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Ultrastructure of the dentin pellicle and the impact of erosion Caries Res. (IF 4.2) Pub Date : 2022-10-28 Anton Schestakow, Christina Bauer, Matthias Hannig
While the ultrastructure of the enamel pellicle and its erosion protective properties are well studied, the dentin pellicle is still neglected in dental research. Therefore, the ultrastructure and erosion protective properties of a pellicle formed on bovine dentin specimens was investigated in the present study. The dentin pellicle was formed in-situ for 3, 30, 120, and 360 min at buccal or palatal
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Prevalence of erosive tooth wear and associated dietary factors among a group of Finnish adolescents Caries Res. (IF 4.2) Pub Date : 2022-10-24 Mirja Methuen, Hanna Kangasmaa, Viivi Karoliina Alaraudanjoki, Anna L. Suominen, Vuokko Anttonen, Hannu Vähänikkilä, Panu Karjalainen, Juuso Väistö, Timo A. Lakka, Marja-Liisa Laitala
The aim of this study was to investigate the prevalence and severity of erosive tooth wear (ETW) among Finnish adolescents and to evaluate how frequency as well as amount of the use of erosive products are associated with ETW. The study population consisted of 328 voluntary, >15-year-old secondary school students (males 49.1%, females 50.9%) in three municipalities in Finland. Clinical examination
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Plaque and dental caries risk in mid-life Caries Res. (IF 4.2) Pub Date : 2022-10-21 Angela M. L. Benn, Nicholas C.K. Heng, William Murray Thomson, Jonathan Mark Broadbent
Dental caries is an endogenous microbial-community-based disease resulting from an ecological shift from dynamic stability to metabolic imbalance in a consortium of acidogenic and aciduric bacteria comprising the dental plaque biofilm. Participants were members of the Dunedin Multidisciplinary Health and Development Study, a longitudinal investigation of health and behaviour in a cohort born in Dunedin
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Effect of a toothpaste containing S-PRG filler on the remineralization of artificial carious enamel lesions in situ Caries Res. (IF 4.2) Pub Date : 2022-10-10 Mariele Vertuan, Júlia França da Silva, Amanda Moura Ferreira, Aline Silva Braga, Ana Carolina Magalhães
This study evaluated the remineralizing effect of a toothpaste containing surface pre-reacted glass-ionomer (S-PRG) filler on demineralized enamel in situ. For this, 180 bovine enamel samples were demineralized by using a microcosm biofilm model for 3 days. Thereafter, the samples were randomly signed to 15 healthy volunteers and to 3 cross-over in situ phases corresponding to the following treatments: