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The mechanism of lncRNA MALAT1 targeting the miR-124-3p/IGF2BP1 axis to regulate osteogenic differentiation of periodontal ligament stem cells Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-16 Nan Gu, Yao Wang, Lingfeng Li, Xin Sui, Zhihui Liu
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Fracture resistance of CAD/CAM endocrowns made from different materials in maxillary premolar interproximal defects Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-16 Fuqian Jin, Xiaoyan Yu, Haolin Zhou, Jin Zhou, Jing Yang, Yi Luo, Zhu Chen
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Influence of the severity of periodontal disease on the outcome of non-surgical endodontic therapy: A prospective cohort study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-15 Arun Kumar Duraisamy, Ajay Logani, Vijay Kumar, Amrita Chawla, Sidhartha Sharma, R. M. Pandey
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Comparing pre- and postoperative etoricoxib administration versus only postoperative on third molar extraction sequelae and oral health quality of life: a prospective quasi-experimental study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-15 Giusy Rita Maria La Rosa, Matteo Consoli, Roula S. Abiad, Angelo Toscano, Eugenio Pedullà
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Analysis of the treatment of RT2 recessions with a xenogeneic collagen matrix vs. connective tissue graft combined with a coronally advanced flap. A double-blinded randomized clinical trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-15 Ruiz-de-Gopegui-Palacios Elena, Vilor-Fernández Miren, García-De-La-Fuente Ana-María, Marichalar-Mendía Xabier, Aguirre-Zorzano Luis-Antonio
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Clinical insights into traumatic injury of the inferior alveolar and lingual nerves: a comprehensive approach from diagnosis to therapeutic interventions Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-15 Peer W. Kämmerer, Diana Heimes, Amely Hartmann, Marco Kesting, Fouad Khoury, Eik Schiegnitz, Daniel G. E. Thiem, Jörg Wiltfang, Bilal Al-Nawas, Wolfgang Kämmerer
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Analyzing working time and efficient caries removal using a novel bioactive caries detecting dye and air polisher prophy for caries excavation: randomised clinical trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-15 Shashirekha Govind, Amit Jena, Sushanta Kumar Kamilla, Neeta Mohanty, Mohammed Abdul Kader, Alexander Maniangat Luke, Noura Abdulaziz Alessa, Ali A. Assiry, Mohmed Isaqali Karobari
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Assessment of bone regeneration after maxillary radicular cyst enucleation with or without bone grafting materials: a retrospective cohort study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-14 Giusy Rita Maria La Rosa, Carlotta Ylenia Priolo, Roula S Abiad, Virginia Rosy Romeo, Emanuele Ambu, Eugenio Pedullà
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Comparing accuracy in guided endodontics: dynamic real-time navigation, static guides, and manual approaches for access cavity preparation – an in vitro study using 3D printed teeth Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-14 Karin Christine Huth, Lukas Borkowski, Anja Liebermann, Frank Berlinghoff, Reinhard Hickel, Falk Schwendicke, Marcel Reymus
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Efficacy of an automatic electric toothbrush with nylon bristles in dental plaque removal: a cross-over randomized controlled trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-14 Maria Denisa Statie, Irene Lomonaco, Michele Nieri, Veronica Giuntini, Debora Franceschi, Lorenzo Franchi
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Healing and long-term prognosis of root-fractured permanent teeth: a retrospective longitudinal study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-12 Natália de Oliveira Murta Pedrosa, Rayner Afonso Santos, Sylvia Cury Coste, Enrico Antônio Colosimo, Juliana Vilela Bastos
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Immediately placed implants using simvastatin and autogenous tooth graft combination in periodontally compromised sites: a randomized controlled clinical trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-12
Abstract Objectives The present study aimed to assess clinically and radiographically the usage of autogenous tooth bone graft (ATBG) combined with and without Simvastatin (SMV) around immediately placed dental implants in periodontally compromised sites. Methods Thirty-nine patients required a single extraction of periodontally compromised tooth were divided into three groups (13 patients each). Group
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Two-year evaluation of a nano-hybrid and a bulk-fill resin composite: a randomized, double-blind split-mouth clinical study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-11 Funda Çağırır Dindaroğlu, Ece Yılmaz
Objectives The aim of this study was to compare the 2-year clinical performance of a bulk-fill composite resin and a nano-hybrid-filled composite resin in 6-12-year-old children in a split-mouth design. Materials and methods This randomized, split-mouth, and double-blind study was conducted on 89 patients aged 6–12 years with caries on bilateral mandibular first molars. In a split-mouth design, restorations
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Evaluation of stress and displacement of maxillary canine during the single canine retraction in the maxillary first premolar extraction cases- A finite element study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-09 Wenbo Zhao, Yu Lou, Weijun Yan
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Sixty-month comperative evaluation of a glass hybrid restorative and a composite resin in non-carious cervical lesions of bruxist individuals Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-09 Uzay Koc Vural, Ece Meral, Esra Ergin, Sevil Gurgan
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Efficacy of articaine anesthesia with needle-free/Comfort-in method and conventional needle injection in dental patients with irreversible pulpitis: a randomized clinical trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-09 Amanda Palmeira Arruda Nogueira, Meire Coelho Ferreira, Cláudia de Castro Rizzi MAIA, Bruna Laís Lins Gonçalves, Etevaldo Maia Filho, Cyrene Piazera Costa , Giulio Gavini, Renata Grazziotin-Soares, Ceci Nunes Carvalho
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Performance of a commercially available Generative Pre-trained Transformer (GPT) in describing radiolucent lesions in panoramic radiographs and establishing differential diagnoses Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-09 Thaísa Pinheiro Silva, Maria Fernanda Silva Andrade-Bortoletto, Thaís Santos Cerqueira Ocampo, Caio Alencar-Palha, Michael M. Bornstein, Christiano Oliveira-Santos, Matheus L. Oliveira
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Effects of Nd:YAG laser irradiation at different energy densities on dentin bond durability under simulated pulpal pressure Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-08 Guangdi Sun, Huan Chen, Huimin Wang, Xue Chen, Fei Wei, Tingting Bai, Song Zhu
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Clinical and thermographic evaluation after lower third molar extractions and the application of different photobiomodulation protocols: double-blind randomised clinical trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-08 Laiz Moreira de Paula, Alessah Carolyna de Andrade Fernandes, Beatriz Castro Evangelista, Francine do Couto Lima-Moreira, Geovana Andrade, João Victor de Andrade Fernandes, Fabrício Luscino Alves de Castro, Virgílio Moreira Roriz
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Diagnostic value of cone beam computed tomography for root canal morphology assessment – a micro-CT based comparison Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-08
Abstract Objectives The aim of this study was to assess cone beam computed tomography (CBCT) as a root canal anatomy diagnostic tool by comparison with micro-CT gold-standard. Materials and methods 216 two-rooted mandibular molars were first scanned in a CBCT device (200 μm voxel size) and posteriorly in a micro-CT scanner (19.61 μm). The volumes were sequentially screened to classify main root canal
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Central giant cell granuloma of the jaws—long-term clinical and radiological outcomes of surgical and pharmacological management Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-07
Abstract Objectives To compare long-term results of different treatment modalities in central giant cell granuloma of the maxillofacial-skeleton. Primary resection may result in major defects. Alternative treatments include pharmacological agents. As yet there has been no consensus on the use of the variety of treatment options, and few studies have reported clarifying long-term results. Materials
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Deep learning methods for fully automated dental age estimation on orthopantomograms Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-07
Abstract Objectives This study aimed to use all permanent teeth as the target and establish an automated dental age estimation method across all developmental stages of permanent teeth, accomplishing all the essential steps of tooth determination, tooth development staging, and dental age assessment. Methods A three-step framework for automatically estimating dental age was developed for children aged
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Biomechanical analysis of alveolar bones with compromised quality supporting a 4-unit implant bridge; a possible association with implant-related sequestration (IRS) Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-07 Youngjae Yoon, Inyeong Kang, Gunwoo Noh, Yong-Dae Kwon
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Immunologic burden links periodontitis to acute coronary syndrome: levels of CD4 + and CD8 + T cells in gingival granulation tissue Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-07 Nezahat Arzu Kayar, İlhami Çelik, Muammer Gözlü, Kemal Üstün, Mihtikar Gürsel, Nilgün Özlem Alptekin
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Clinical outcomes of narrow- and regular-diameter implants with bone augmentation in the anterior maxilla: a systematic review and meta-analysis Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-06
Abstract Objectives To evaluate the clinical outcomes of narrow-diameter implants (NDIs) and regular-diameter implants (RDIs) with bone augmentation in the anterior maxilla, with implant survival rate (ISR) as the primary outcome. Additionally, secondary outcomes such as peri-implant marginal bone loss (MBL), pocket probing depth (PPD), mechanical complications, and biological complications were also
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Comparative bioactivity and immunomodulatory potential of the new Bioroot Flow and AH Plus Bioceramic sealer: An in vitro study on hPDLSCs Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-05 José Luis Sanz, Sergio López-García, David García-Bernal, Francisco Javier Rodríguez-Lozano, Leopoldo Forner, Adrián Lozano, Laura Murcia
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Maternal periodontitis may cause lower birth weight in children: genetic evidence from a comprehensive Mendelian randomization study on periodontitis and pregnancy Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-05 Xixiong Chen, Xiao Li, Kun Yang, Jinlin Fang
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Relationships between functional temporomandibular joint space and disc morphology, position, and condylar osseous condition in patients with temporomandibular disorder Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-04 Jinyi Zhu, Yanji Gong, Fangjie Zheng, Deqiang Yin, Yang Liu
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Removal of fiber posts using conventional versus guided endodontics: a comparative study of dentin loss and complications Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-04 R. Krug, F. Schwarz, C. Dullin, W. Leontiev, T. Connert, G. Krastl, F. Haupt
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Evaluation of the effect of extraction in comparison to distalization on the maxillary third molars in class II malocclusion: a retrospective study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-04 Amira A. Aboalnaga, Ahmed S. Fouda
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The outcome of combined use of iRoot BP Plus and iRoot SP for root-end filling in endodontic microsurgery: a randomized controlled trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-02
Abstract Objectives Root-end filling is important for the clinical outcome of endodontic microsurgery. Our previous study showed that combined application of iRoot BP Plus Root Repair Material (BP-RRM) and iRoot SP Injectable Root Canal Sealer (SP-RCS) in root-end filling exhibited better apical sealing as compared to the application of BP-RRM alone. The aim of this randomized controlled clinical trial
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Assessment of color changes and adverse effects of over-the-counter bleaching protocols: a systematic review and network meta-analysis Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-02 Murilo Navarro de Oliveira, Maria Tereza Campos Vidigal, Walbert Vieira, Caio Luiz Lins-Candeiro, Leandro Machado Oliveira, Gustavo G. Nascimento, Gisele Rodrigues da Silva, Luiz Renato Paranhos
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Assessment of wear characteristics, longevity and stiffness of Essix-type retainers Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-02 Lina Alfadil, Mangala Patel, Nikolaos Pandis, Padhraig S. Fleming
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Effect of sodium hypochlorite gel on bacteria associated with periodontal disease Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-02 Delia Irani, Gert Jungbauer, Anton Sculean, Sigrun Eick
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A retrospective cohort study of pulp prognosis in luxated permanent teeth: a competing risk analysis Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-02 Sylvia Cury Coste, Márcio Augusto Ferreira Rodrigues, Júlia Ferreira Maciel Chaves, Thiago César da Silva Lima, Enrico Antônio Colosimo, Juliana Vilela Bastos
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Machine learning-based medical imaging diagnosis in patients with temporomandibular disorders: a diagnostic test accuracy systematic review and meta-analysis Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-02 Yunan Zhang, Tao Zhu, Yunhao Zheng, Yutao Xiong, Wei Liu, Wei Zeng, Wei Tang, Chang Liu
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Comparison of efficacy of thermoplastic retainer with round and rectangular bonded lingual wire retainer in the mandible two years after orthodontic treatment: a randomised controlled trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-01 Silvija Kanizaj Ugrin, Stjepan Špalj
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Evaluation of bone contact area and intercondylar distance changes in orthognathic surgery - a comparison between BSSO and HSSO technique depending on mandibular displacement extent Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-01 Stephan Christian Möhlhenrich, Kristian Kniha, Florian Peters, Marius Heitzer, Josef Szalma, Andreas Prescher, Gholamreza Danesh, Frank Hölzle, Ali Modabber
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Oral manifestations in women using hormonal contraceptive methods: a systematic review Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-01 Marta García Rojo, Miguel Ramón Pecci Lloret, Julia Guerrero Gironés
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Bone formation in large/moderate gap after immediate implantation in response to different treatments: a pre-clinical study in the canine posterior mandible Clin. Oral Investig. (IF 3.4) Pub Date : 2024-03-01
Abstract Objectives This study aims to investigate different treatments on new bone formation around immediate implants in the canine posterior mandible with varying sized mesial-distal gap. Materials and methods The 4th premolar and the 1st molar of six Labrador dogs were extracted from the mandible, and 4 dental implants were placed 1 mm below the level of the buccal bone crest. Moderate/large mesial-distal
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Cyanoacrylate tissue adhesive versus silk sutures for mandibular third molar surgery: a systematic review and meta-analysis Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-29
Abstract Objective Cyanoacrylate tissue adhesive has been presented as an alternative to sutures and several studies have compared them. The objective of this meta-analysis was to evaluate the effect of cyanoacrylate tissue adhesive on postoperative pain and swelling, following mandibular third molar surgery. Materials and Methods Database search was conducted in MEDLINE/PubMed and Scopus, along with
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Efficacy of acellular xenogeneic dermal matrix graft in the treatment of multiple gingival recessions: systematic review and meta-analysis Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-27
Abstract Objective This study aimed to compare the efficacy of acellular xenogeneic dermal matrix graft (AXDM) compared to connective tissue graft (CTG) in treating multiple gingival recessions. Materials and methods A systematic search of electronic databases was conducted to identify randomized clinical trials (RCTs) that compared AXDM and CTG. The selected studies were subjected to bias risk assessment
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A novel deep learning-based perspective for tooth numbering and caries detection Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-27
Abstract Objectives The aim of this study was automatically detecting and numbering teeth in digital bitewing radiographs obtained from patients, and evaluating the diagnostic efficiency of decayed teeth in real time, using deep learning algorithms. Methods The dataset consisted of 1170 anonymized digital bitewing radiographs randomly obtained from faculty archives. After image evaluation and labeling
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Biological response to endodontic treatment in one versus two-visit: a systematic review and meta-analysis of animal studies Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-26 Raimundo Sales de Oliveira Neto, Thais de Moraes Souza, Stefani Jovedi Rosa, Rodrigo Ricci Vivan, Murilo Priori Alcalde, Heitor Marques Honório, Marco Antonio Hungaro Duarte
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Does surface enamel composition and characteristics vary with inter proximal enamel reduction? Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-26 Kishore B. Poovattil, Haritha P. Sathyanarayana, Sridevi Padmanabhan
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Is it possible to extract primary maxillary molars without palatal injection?: a controlled clinical trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-26 Esra Ceren TUĞUTLU, Kevser SANCAK
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The efficacy of 2780 nm Er,Cr;YSGG and 940 nm Diode Laser in root canal disinfection: A randomized clinical trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-26 Sara Zakaria Fahim, Rami Maher Ghali, Ahmed A. Hashem, Mary Medhat Farid
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The bevel effect: a prospective, randomized investigation into needle design in dental intraligamentary anesthesia Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-24 P. W. Kämmerer, H. Staedt, K. Wesslau, I. Buttchereit, H. L. Stiller, T. Frankenberger, M. Dau
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Low and high hydrogen peroxide concentrations of in-office dental bleaching associated with violet light: an in vitro study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-24 Isabela Souza Vardasca, Michael Willian Favoreto, Mylena de Araujo Regis, Taynara de Souza Carneiro, Emanuel Adriano Hul, Christiane Philippini Ferreira Borges, Alessandra Reis, Alessandro D. Loguercio, Carlos Francci
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The impact of craniofacial and dental osteogenesis imperfecta manifestations on oral health-related quality of life of children and adolescents Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-24 Leticia L. Quirino Pantoja, Mariana Candida Vaz Carvalho, Paulo Marcio Yamaguti, Luiz Claudio Castro, Lilian Marly Paula, Ana Carolina Acevedo
Objective Craniofacial and oral manifestations of Osteogenesis Imperfecta (OI) can affect the functioning of the stomatognathic system and impact the patient’s quality of life. The objective of the study was to evaluate the relationship between craniofacial and oral manifestations and the Oral Health-related Quality of Life (OHRQoL) of OI children and adolescents. Material and Methods: A total of 30
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The relationship of dietary flavonoids and periodontitis in US population: a cross-sectional NHANES analysis Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-24 Yundong Liu, Tao Yin, Mi He, Changyun Fang, Shifang Peng
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Clinical outcomes of endodontic microsurgery in complicated cases with large or through-and-through lesions: a retrospective longitudinal study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-24 Xiaoxia Yang, Xuan Chen, Yinchun Zhang, Lei Huang, Dongjie Chen, Qinfang Zeng, Xiaoling Qiu
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The effect of nano silver fluoride, self-assembling peptide and sodium fluoride varnish on salivary cariogenic bacteria: a randomized controlled clinical trial Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-23
Abstract Objectives To compare the antibacterial effect of Nanosilver Fluoride varnish (NSF) varnish, P11-4 and Sodium Fluoride (NaF) varnish against salivary Streptococcus mutans (S. mutans) and Lactobacilli. Methods 66 patients aged 10–24 years old were randomly assigned to receive single application of NSF, P11-4 or NaF varnish. Baseline unstimulated saliva samples were collected before the agents
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The repeatability of periodontal imaging with intraoral ultrasound scanning Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-22
Abstract Objective Ultrasound is a non-invasive and low-cost diagnostic tool widely used in medicine. Recent studies have demonstrated that ultrasound imaging might have the potential to be used intraorally to assess the periodontium by comparing it to current imaging methods. This study aims to characterize the repeatability of intraoral periodontal ultrasound imaging. Materials and methods Two hundred
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Whiplash trauma did not predict jaw pain after 2 years: an explorative study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-22 Alicia Böthun, Anna Lövgren, Britt-Marie Stålnacke, Ewa Lampa, Catharina Österlund, Birgitta Häggman-Henrikson, Fredrik Hellström
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Microcomputed tomographic evaluation of 6 NiTi files on the pericervical dentin and the smallest dentin thickness zones in mesial root canals of mandibular molars: an in vitro study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-22
Abstract Objective The aim of this study was to evaluate six files on the pericervical dentin (PCD) and the smallest dentin thickness zones (SDTZ) in mesial root canals of mandibular molars. Materials and methods Sixty mandibular molars with two mesial canals and Vertucci configuration were aleatory allocated in 6 experimental groups of 10 molars and 20 root canals. Specimens were scanned before instrumentation
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Simultaneous standard total joint prosthesis reconstruction with SSRO and Le Fort I osteotomy in the treatment of unilateral temporomandibular joint ankylosis with jaw deformity: a case cohort study Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-21
Abstract Objective Unilateral temporomandibular joint ankylosis with jaw deformity (UTMJAJD) may require simultaneous total joint prosthesis (TJP) reconstruction, sagittal split ramus (SSRO), and Le Fort I osteotomies. The purpose of this study was to evaluate outcomes in patients treated with these procedures. Methods Patients diagnosed UTMJAJD between 2016 and 2018 were selected for the study. Mandible-first
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The effect of tongue reduction for preventing adverse effects in patients undergoing class III orthognathic surgery: a three-dimensional comparative analysis Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-21 Bong-Jin Jeong, Joo-Young Ohe, Jae-In Ryu, Byung-Joon Choi, Junho Jung
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Impact of enhancement filters of a CMOS system on halo artifact expression at the bone-to-implant interface Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-21
Abstract Objective To assess the impact of enhancement filters on the formation of halo artifacts in radiographs of dental implants obtained with a complementary metal oxide semiconductor (CMOS) system. Methods Digital radiographs of dental implants placed in dry human mandibles were processed with the Noise Reduction smoothing filter, as well as the Sharpen 1, Sharpen 4, and Sharpen UM high-pass filters
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Occlusal equilibration and muscle activity in fixed versus removable mandibular implant supported overdenture Clin. Oral Investig. (IF 3.4) Pub Date : 2024-02-21 Asmaa N. Elboraey, Wessam M. Dehis, Sherihan M. Eissa, Menatallah Mohamed El-Hotieby, Omar K. Abdelkader