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Further Interventions After Root Canal Treatment Are Most Common in Molars and Teeth Restored with Direct Restorations: A 10–11-Year Follow-Up of the Adult Swedish Population J. Endod. (IF 4.2) Pub Date : 2024-03-15 Victoria S. Dawson DDS PhD, Helena Fransson DDS PhD, Per-Erik Isberg, EndoReCo, Lars Bjørndal DDS PhD, Victoria S. Dawson DDS PhD, Helena Fransson DDS PhD, Fredrik Frisk DDS PhD, Peter Jonasson DDS PhD, Thomas Kvist DDS PhD, Merete Markvart DDS PhD, Maria Pigg DDS PhD, Emma Wigsten DDS PhD, Emma Wigsten DDS PhD
The aims were to investigate 1) the frequency of nonsurgical retreatment, root-end surgery, extraction, and further restorative treatment during a follow-up of 10 to 11 years after root filling and compare the frequencies according to tooth group and type of coronal restoration, and 2) the timing of nonsurgical retreatment, root-end surgery, and extraction. Data were collected from the Swedish Social
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Systemic Corticosteroid Uses in Endodontics- Part 1: Managing Postoperative Pain J. Endod. (IF 4.2) Pub Date : 2024-03-14 Norah Alajlan B.D.S. M.S, Alonso Carrasco-Labra D.D.S. M.Sc. Ph.D, Bekir Karabucak D.M.D. M.S, Su-Min Lee D.D.S. M.S.D. D.Sc.D
This study aimed to systematically search and review all available literature regarding systemic (oral or locally injected) corticosteroids in endodontics to assess their effect on postoperative pain. A search was conducted using PubMed, Cochrane Library, Embase, Scopus, Dentistry & Oral Science, and ProQuest. Randomized controlled trials enrolling participants undergoing endodontic treatment and assessing
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Systemic Corticosteroid Uses in Endodontics- Part 2: Enhancing the Success of Local Anesthesia J. Endod. (IF 4.2) Pub Date : 2024-03-13 Norah Alajlan B.D.S. M.S, Alonso Carrasco-Labra D.D.S. M.Sc. Ph.D, Bekir Karabucak D.M.D. M.S, Su-Min Lee D.D.S. M.S.D. D.Sc.D
Chronic inflammation in irreversible pulpitis leads to heightened sensitivity of nociceptive receptors, resulting in persistent hyperalgesia. This poses significant challenges in achieving effective anesthesia for patients with irreversible pulpitis. Various anesthetic techniques and pharmacological approaches have been employed to enhance the success of local anesthesia. Recently, the preemptive use
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Developing Advanced Patient-Specific In-Silico Models: A New Era in Biomechanical Analysis of Tooth Autotransplantation J. Endod. (IF 4.2) Pub Date : 2024-03-05 Pierre Lahoud, Reinhilde Jacobs, Seyed Ali Elahi, Maxime Ducret, Wout Lauwers, G. Harry van Lenthe, Raphaël Richert, Mostafa EzEldeen
As personalized medicine advances, there is an escalating need for sophisticated tools to understand complex biomechanical phenomena in clinical research. Recognizing a significant gap, this study pioneers the development of patient-specific in-silico models for tooth autotransplantation (TAT), setting a new standard for predictive accuracy and reliability in evaluating TAT outcomes. Development of
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Effects of sodium hypochlorite concentration and application time on bacteria in an ex vivo polymicrobial biofilm model J. Endod. (IF 4.2) Pub Date : 2024-03-05 Hazuki Maezono DDS PhD, Kittipit Klanliang DDS PhD, Tsuyoshi Shimaoka DDS, Yoko Asahi DDS PhD, Yusuke Takahashi DDS PhD, Zhejun Wang DDS PhD, Ya Shen DDS PhD, Markus Haapasalo DDS PhD, Mikako Hayashi DDS PhD
In endodontic treatment, it is important to remove or inactivate biofilms in the root canal system. We investigated the effects of different concentrations and application times of sodium hypochlorite (NaOCl) on the viability of bacteria in polymicrobial biofilms of different maturation levels. Polymicrobial biofilms were prepared from dental plaque samples and grown for 1, 2, and 3 weeks under anaerobic
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The evaluation of anti-osteoclastic activity of the novel calcium hydroxide biodegradable nanoparticles as an intracanal medicament J. Endod. (IF 4.2) Pub Date : 2024-03-04 Patarawadee Promta, Patcharaporn Chaiyosang, Aussara Panya, Pongrapee Laorodphun, Warat Leelapornpisid, Napatsorn Imerb
The aim of this study was to evaluate the anti-osteoclastic activity of calcium hydroxide-loaded poly(lactic-co-glycolic acid) nanoparticles (Ca(OH)-loaded PLGA NPs) in comparison to calcium hydroxide nanoparticles (Ca(OH) NPs). RAW 264.7 cell lines (third-fifth passage) were cultured and incubated with soluble receptor activator of nuclear factor-κB ligand (RANKL) in triplicates. Subsequently, Ca(OH)-loaded
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Insights into the April 2024 Issue of the Journal of Endodontics J. Endod. (IF 4.2) Pub Date : 2024-03-03 Anita Aminoshariae DDS MS, Amir Azarpazhooh DDS MSc PhD FRCD(C), Ashraf F. Fouad DDS MS, Gerald N. Glickman DDS MS MBA JD, Jianing He DMD PhD, Sahng G. Kim DDS MS, Anil Kishen BDS MDS PhD, Ariadne M. Letra DDS MS PhD, Linda Levin DDS PhD, Frank C. Setzer DMD PhD MS, Franklin R. Tay BDSc(Hons) PhD, Kenneth M. Hargreaves DDS PhD
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Retrospective follow-up assessment of risk variables influencing the outcome of autologous tooth transplantation J. Endod. (IF 4.2) Pub Date : 2024-03-03 Felipe A. Restrepo-Restrepo DDS MDent, Diego F. Uribe-Jaramillo DDS MDent, Paula A. Villa-Machado DDS MDent, José L. Mejía-Cardona DDS MDent, Francesc Abella-Sans DDS MSc, Reyna K. Morales-Quezada DDS Mdent, Sergio I. Tobón-Arroyave DDS MDent
This retrospective study aimed to identify which patient-, donor tooth-, recipient site-, and surgical procedure-related variables may influence the outcome of tooth autotransplantation. The sample included 128 autotransplants performed in 122 patients. Single‐visit clinical/imaging examinations were used to define the outcome as successful, survival, or failure. The association of potential indicators
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Comparative Analysis of AH Plus Bond Strength to Root Canal Dentin and Adhesive Interface Quality after Calcium Hydroxide Removal using Different Irrigation Protocols J. Endod. (IF 4.2) Pub Date : 2024-03-01 Julia Menezes Savaris, Jackson Carlos Isoton, Bruna Fiorine Fluck, Maybell Tedesco, Eduardo Antunes Bortoluzzi, Lucas da Fonseca Roberti Garcia, Cleonice da Silveira Teixeira
To evaluate the push-out bond strength (POBS) of AH Plus sealer to root dentin and the adhesive interface quality after calcium hydroxide (Ca(OH)) intracanal dressing removal with different final irrigation protocols. After root canal instrumentation and irrigation, 40 root canals were filled with Ca(OH) and sealed. After 14 days, the specimens were randomly distributed according to the irrigation
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Restoration of Teeth with Severely Compromised Tooth Structure using Digital Planning Combined with Orthodontic Magnetic Extrusion—A Report of 2 Cases J. Endod. (IF 4.2) Pub Date : 2024-02-29 Jaume Casaponsa DDS MSc, Thilla Sekar Vinothkumar BDS MDS FDS RCPS (Glasg) FICD FPFA PhD, Paul M.H. Dummer BDS MScD PhD DDSc FDS RCS (Ed), Venkateshbabu Nagendrababu BDS MDS FDS RCPS (Glasg) PhD, Francesc Abella Sans DDS PhD
This report outlines 2 digitally planned cases in which the teeth underwent magnetic extrusion to preserve the supracrestal tissue attachment and regain the ferrule, followed by their restoration. Case 1: A 42-year-old man with the chief concern of a fractured right maxillary second premolar. Following the completion of root canal treatment, the remaining tooth structure was insufficient to create
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Evaluation of Bone Growth around Autotransplanted Teeth Using Cone-Beam Computed Tomographic Images J. Endod. (IF 4.2) Pub Date : 2024-02-29 Ludimila Saiter Assis Beltrame DDS MSc, Juliana Delatorre Bronzato DDS PhD, Tereza Jacy da Silva Almeida DDS MSc, João Batista Gagno Intra DDS MSc PhD, Fernanda Carneiro Nunes DDS MSc, Cleber de Freitas Britto DDS MSc, Natalia Barcellos de Freitas Coutinho DDS MSc, Glauco Rangel Zanetti DDS MSc PhD, Marcos Frozoni DDS MSc PhD
The aim of this observational study was to evaluate bone growth at the recipient site of autotransplanted teeth using cone-beam computed tomography (CBCT) images and to compare it to the control tooth. Bone growth was measured on CBCT images obtained from the anterior region of the maxilla, which received a single transplant of immature premolars due to early loss of the central incisor. The results
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Letter to the Editor: Consort Randomized Clinical Trial J. Endod. (IF 4.2) Pub Date : 2024-02-22 George Bogen BS DDS
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Artificial Intelligence in Endodontic Education J. Endod. (IF 4.2) Pub Date : 2024-02-21 Anita Aminoshariae DDS MS, Ali Nosrat DDS MS MDS, Venkateshbabu Nagendrababu BDS MFDS RCPS(Glasg) MDS FDS RCSP(Glasg) PhD, Omid Dianat DDS MS, Hossein Mohammad-Rahimi DDS, Abbey W. O'Keefe MD, Frank C. Setzer DMD PhD MS
The future dental and endodontic education must adapt to the current digitalized healthcare system in a hyper-connected world. The purpose of this scoping review was to investigate the ways an endodontic education curriculum could benefit from the implementation of artificial intelligence (AI) and overcome the limitations of this technology in the delivery of healthcare to patients. An electronic search
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Assessing the Impact of the Metal Artifact Reduction Tool on Detecting Furcation Lesions in Maxillary Molars with Different Intracanal Posts: An Ex Vivo Cone-beam Computed Tomography Study J. Endod. (IF 4.2) Pub Date : 2024-02-21 Mayara Fidelis Bastos MSc DDS, Maria Augusta Visconti PhD, Rafael Rocha Pinto MSc DDS, Rafael Binato Junqueira PhD, Francielle Silvestre Verner PhD
Considering the potential image compromise and diagnostic challenges posed by metals, this study aimed to assess the efficacy of the metal artifact reduction (MAR) tool in cone-beam computed tomography examinations for detecting furcation lesions in upper molars treated endodontically and restored with different intracanal posts. This study used 45 endodontically treated maxillary first molars, categorized
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Nicolau Syndrome with Severe Facial Ischemic Necrosis after Endodontic Treatment: A Case Report J. Endod. (IF 4.2) Pub Date : 2024-02-20 Qiongyi Kang, Zhengwei Huang, Wentao Qian
Nicolau syndrome (NS) is a rare complication resulting from intramuscular injections. It is characterized by severe pain at the injection site and the development of purplish discoloration. Only a limited number of case reports have been published documenting the adverse effects associated with the injection of calcium hydroxide (CH) beyond the apex during endodontic treatment. Here, we present the
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Revolutionizing Endodontics: Innovative Approaches for Treating Mature Teeth With Closed Apices and Apical Lesions: A Report of Two Cases J. Endod. (IF 4.2) Pub Date : 2024-02-20 Claudia Brizuela PhD, Gastón Meza DDS, Maroun Khoury PhD
Modern tissue engineering strategies have elucidated the potential of regenerative endodontic treatment (RET) as an alternative for treating mature teeth. Here, we report two cases in which cell-based RET (CB-RET) using encapsulated allogeneic umbilical cord mesenchymal stem cells (UC-MSCs) in a platelet-poor plasma (PPP)-based scaffold was used in two mature teeth with pulp necrosis and apical periodontitis
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Comparative Analysis of Irrigation Techniques for Cleaning Efficiency in Isthmus Structures J. Endod. (IF 4.2) Pub Date : 2024-02-20 David Donnermeyer PD Dr.med.dent., Patricia Claire Dust, Edgar Schäfer Prof.Dr.med.dent., Sebastian Bürklein Prof.Dr.med.dent.
This study aimed to evaluate the removal of a biofilm-mimicking hydrogel from isthmus structures in a simulated complex root canal system consisting of 2 curved root canals by Laser-activated irrigation (LAI, AdvErl Evo, Morita) and mechanical activation techniques. A 3D-printed root canal model with 2 parallel root canals (60°-curvature, radius 5 mm, dimension 25/.06) with a total length of 20 mm
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How Does Intentional Apical Foraminal Enlargement Affect the Foramen and Root Canal Morphology? J. Endod. (IF 4.2) Pub Date : 2024-02-20 Tamer Ferreira Schimdt DDS MSc PhD, Lucas da Fonseca Roberti Garcia DDS MSc PhD, Cleonice da Silveira Teixeira DDS MSc PhD, Murilo Priori Alcalde DDS MS PhD, Marco Antonio Hungaro Duarte DDS MSc PhD, Eduardo Antunes Bortoluzzi DDS MSc PhD
This study assessed the effect of intentional foraminal enlargement on the foramen and the apical root canal morphology. Sixty mesial roots of mandibular molars were scanned by micro-computed tomography. Their apical foramina were photographed with a stereomicroscope before and after preparation. Three groups were formed ( = 20) according to the working length (WL). G-1: foramen - 1 mm; G0: foramen;
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Ozone and Laser Effects on Dentin Hypersensitivity Treatment: A Randomized Clinical Study J. Endod. (IF 4.2) Pub Date : 2024-02-19 Maurizio D’Amario DDS PhD, Mariachiara Di Carlo DDS, Ali Jahjah, Stefania Mauro DDS, Salvatore Natale MD, Mario Capogreco DDS
The aim of this study was to evaluate and compare the clinical efficacy of diode laser and ozone gas in the treatment of dentin hypersensitivity (DHS). One hundred thirty-two teeth from 44 patients with moderate DHS were randomized into 3 groups according to a split-mouth design. In the diode laser group, the operator irradiated the superficial dentin exposed with an 808-nm wavelength and incremental
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Proposed Diagnostic Reference Levels in the Missouri/Southern Illinois Region Associated with Cone-beam Computed Tomography Use in Endodontics J. Endod. (IF 4.2) Pub Date : 2024-02-19 Arthur Popkowski DDS, S. Craig Rhodes DMD MSD, John F. Hatton DMD
Diagnostic reference levels (DRLs) are intended to improve patient safety and ensure that patient ionizing radiation doses are as low as reasonably achievable. The purpose of this dosimetry study was to establish regional DRL levels for cone-beam computed tomography (CBCT) imaging for specialty endodontics. Another aim was to compare phantom-measured ionizing radiation dose index 1 (DI1) index doses
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Endodontic Microsurgery With an Autonomous Robotic System: A Clinical Report J. Endod. (IF 4.2) Pub Date : 2024-02-17 Chen Liu PhD, Xin Liu MD, Xin Wang MD, Yuchen Liu PhD, Yu Bai PhD, Shizhu Bai PhD, Yimin Zhao PhD
Endodontic microsurgery (EMS) requires minimally invasive osteotomy and accurate root-end resection, which can be challenging in many instances. Evidence suggests that autonomous robotic systems can significantly enhance the precision of dental implantation. The aim of this case report is to introduce a novel EMS technique that employs robot-guided osteotomy and root resection procedures. A 59-year-old
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Augmented Reality Head-Mounted Device and Dynamic Navigation System for Postremoval in Maxillary Molars J. Endod. (IF 4.2) Pub Date : 2024-02-17 Frederico C. Martinho DDS MS PhD, Syed J. Qadir DDS, Ina L. Griffin DMD, Mary Anne S. Melo DDS MS PhD, Guadalupe G. Fay DDS MS
This study evaluates the feasibility of an augmented reality (AR) head-mounted device (HMD) displaying a dynamic navigation system (DNS) in the surgical site for fiber postremoval in maxillary molars and compares it to the DNS technique. Fifty maxillary first molars were divided into 2 groups: AR HMD + DNS ( = 25) and DNS ( = 25). The palatal canal was restored with RelyX fiber post (3M ESPE) luted
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Pericervical Dentin Metrics in Mandibular First Molars Determined with Digital Periapical Radiography and Cone-beam Computed Tomography J. Endod. (IF 4.2) Pub Date : 2024-02-14 Carlos Boveda Od Endod Esp Endod PhD, Anil Kishen BDS MDS PhD, Beatriz Millan Od Esp Endod PhD, María V. Camejo Od Esp Endod PhD, Jose Francisco Gomez-Sosa DDS PhD
Pericervical root dentin is decisive for the long-term mechanical integrity of root-filled teeth. Current treatment protocol does not include a customized step to determine the pretreatment residual pericervical root dentin. To determine and compare the residual root dentin and canal width using digital periapical radiography (DPR) and cone-beam computed tomography (CBCT) at the apical limit of the
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Long-Term Outcome of Horizontal Root Fractures in Permanent Teeth: A Retrospective Cohort Study J. Endod. (IF 4.2) Pub Date : 2024-02-13 Mahshid Sheikhnezami, Reza Shahmohammadi, Hamid Jafarzadeh, Amir Azarpazhooh
Horizontal root fracture (HRF) is a complex traumatic dental injury that affects the pulp, dentin, cementum, and periodontal ligament. This retrospective cohort study evaluated treatment outcomes in permanent teeth with HRF. We analyzed clinical and radiographic data from a dental trauma center (2006-2022). Permanent teeth with HRF with a follow up of ≥12 weeks were considered for outcome assessment
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External Validation of the Effect of the Combined Use of Object Detection for the Classification of the C-Shaped Canal Configuration of the Mandibular Second Molar in Panoramic Radiographs: A Multicenter Study J. Endod. (IF 4.2) Pub Date : 2024-02-08 Sujin Yang DDS PhD, Kee-Deog Kim DDS MSD PhD, Yoshitaka Kise DDS PhD, Michihito Nozawa DDS PhD, Mizuho Mori DDS, Natsuho Takata DDS, Akitoshi Katsumata DDS PhD, Yoshiko Ariji DDS PhD, Wonse Park DDS MSD PhD, Eiichiro Ariji DDS PhD
The purposes of this study were to evaluate the effect of the combined use of object detection for the classification of the C-shaped canal anatomy of the mandibular second molar in panoramic radiographs and to perform an external validation on a multicenter dataset. The panoramic radiographs of 805 patients were collected from 4 institutes across two countries. . Five datasets were generated: one
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Insights into the March 2024 Issue of the JOE J. Endod. (IF 4.2) Pub Date : 2024-02-08 Anita Aminoshariae, Amir Azarpazhooh, Ashraf F. Fouad, Gerald N. Glickman, Jianing He, Sahng G. Kim, Anil Kishen, Ariadne M. Letra, Linda Levin, Frank C. Setzer, Franklin R. Tay, Kenneth M. Hargreaves
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ACCURACY OF MAGNETIC RESONANCE IMAGING IN CLINICAL ENDODONTIC APPLICATIONS: A SYSTEMATIC REVIEW J. Endod. (IF 4.2) Pub Date : 2024-01-28 Amanda Pelegrin Candemil, Guilherme N. Alves dos Santos, Matheus L. Oliveira, Filippo Gatti, Yara T.C. Silva-Sousa, Alice C. Silva-Sousa, Jardel Francisco Mazzi-Chaves, Manoel Damião Sousa-Neto
Introduction The development of dedicated coils and new Magnetic Resonance Imaging (MRI) sequences has led to an increase in image resolution and a reduction in artifacts. Consequently, numerous studies have demonstrated the utility of MRI as a non-ionizing alternative to cone-beam computed tomography (CBCT). The aim of this systematic review was to evaluate the accuracy of MRI in clinical applications
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Effect of MT-technology of Heat Treatment on Reciproc: Comparison of Reciproc, Reciproc Blue and Reciproc MT J. Endod. (IF 4.2) Pub Date : 2024-02-02 Zunduijamts Odgerel, Sang Won Kwak, Jung-Hong Ha, Gianluca Gambarini, Ya Shen, Hyeon-Cheol Kim
This study aimed to evaluate the effects from the memory-triple (MT) heat treatment on the fatigue resistance of the Reciproc by comparison to the file systems of same geometry. Reciproc files subjected to MT heat treatment technology were designated as Group RMT were compared with the original Reciproc (Group REC) and Reciproc Blue (Group REB). Each NiTi file from three groups ( = 15) was operated
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Multiple External Cervical Resorption Lesions in Patient with Graft versus Host Disease Treated with Systemic Bleomycin: A Case Report J. Endod. (IF 4.2) Pub Date : 2024-02-02 Daniel Merrick, Henry F. Duncan, Andrew Bolas, Annie Hughes, Michael O'Sullivan
The phenomenon of multiple external cervical root resorption (ECRR) lesions in a single patient is rare but may have a link with chemotherapeutic agent Bleomycin. This case details an adult male with multiple ECRR lesions that developed following chemotherapy. His treatment regime for Hodgkin’s lymphoma included the chemotherapeutic antibiotic Bleomycin, which has previously been linked with development
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IN VITRO EVALUATION OF THE DYNAMIC CYCLIC FATIGUE RESISTANCE OF A NEW TRUNATOMY GLIDER FILE AFTER DIFFERENT CYCLES OF USE J. Endod. (IF 4.2) Pub Date : 2024-02-02 Lorena Ferreira Rego, Juliana Delatorre Bronzato, Alana Pinto Carôso Souza, Adriana de-Jesus-Soares, Marcos Frozoni
Determination of the glide path is recommended before using rotary instruments. This study aimed to evaluate the dynamic cyclic fatigue resistance of new and used glider rotary instruments in up to six root canals. Seventy-two TruNatomy Glider files were used for the preparation of root canals of extracted lower molars, which were then submitted to the dynamic cyclic fatigue test carried out in a curved
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Correlation Between Proinflammatory Cytokine Expression and Clinical Data in Apical Granuloma J. Endod. (IF 4.2) Pub Date : 2024-02-02 Renata C.V. Rodrigues, Mariana T.M. Porpino, Nilton Dessaune-Neto, Henrique S. Antunes, Karina M.M.C. Pinto, José C. Provenzano, Fábio R. Pires, José F. Siqueira Jr., Luciana Armada
This study was intended to evaluate the expression of inflammatory cytokines commonly secreted by CD4+ T cells (IL-2, IL-5, IL-17, TGF-β, TNF-α and IFN-γ) in apical granulomas and correlate with the clinical conditions and time elapsed since root canal treatment. Eighteen biopsy specimens obtained by periradicular surgery of teeth with post-treatment apical periodontitis and diagnosed as apical granuloma
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Two-dimensional radiographs and CBCT assessment of concentrated growth factor and platelet-rich fibrin scaffolds in regenerative endodontic treatment of immature incisors with periapical radiolucency: a randomized clinical trial J. Endod. (IF 4.2) Pub Date : 2024-01-27 Ahmad Abdel Hamid Elheeny, Ghada Eslaman Tony
Introduction The primary aim of this study was to compare the radiographic changes of immature incisors with periapical radiolucency after treatment with platelet-rich fibrin (PRF) and concentrated growth factor (CGF) platelet concentrate scaffolds as well as assessment of the clinical success rate over 12 months. The secondary aim was to monitor the radiographic changes in terms of reduction of periapical
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Robot Assisted and Haptic Guided Endodontic Surgery: A case report J. Endod. (IF 4.2) Pub Date : 2024-01-26 Almira Isufi, Tun-Yi Hsu, Sami Chogle
There has been a significant increase in robot-assisted dental procedures in the last decade. Particularly in the area of robot-assisted implant placement. The objective of this case report was to assess the initial use of Yomi® Robot's (Neocis Inc, Miami, Fl) assistance and haptic guidance during endodontic microsurgery. The robot was utilized during the osteotomy and root-end resection of the first
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Outcome of Contemporary Nonsurgical Endodontic Retreatment: A Systematic Review of Randomized Controlled Trials and Cohort Studies J. Endod. (IF 4.2) Pub Date : 2024-01-26 M. Sabeti, Y.J. Chung, N. Aghamohammadi, A. Khansari, R. Pakzad, A. Azarpazhooh
Introduction The success rates of NS-ReTx have varied across decades of prior research. Nonetheless, recent endodontic advances have substantially enhanced case management. This systematic review aimed to identify rigorous studies on contemporary NS-ReTx, investigating both periapical healing—evaluated strictly for complete resolution or loosely for size reduction of periapical radiolucency—and success
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Worldwide Anatomic Characteristics of the Mandibular Canine – A Multi-Center Cross-Sectional Study with Meta-Analysis J. Endod. (IF 4.2) Pub Date : 2024-01-26 Jorge N.R. Martins
Introduction This study aimed to examine the global prevalence of root and root canal morphologies in mandibular canines and analyze potential influences of region, ethnicity, sex, and age on the proportion of a second root and root canal configuration. Methods Observers from 44 countries screened 13,200 canines using cone-beam computed tomographic exams and gather data on the percentages of 2 root
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High Fat Diet Influences Dendritic Cells and T Cells Infiltration in Apical Periodontitis in Mice J. Endod. (IF 4.2) Pub Date : 2024-01-26 Annie Shrestha, Yi Zhu, Aiman Ali
Introduction Diet-induced metabolic syndrome may influence the progression and healing of apical periodontitis (AP). The aim of this study is to evaluate the inflammatory immune response of dendritic cells (DCs) and T helper (Th) cells in normal versus obese mice with AP. Methods Twenty male C57BL/6 mice were divided into two groups: normal chow (NC) and high-fat diet (HFD) for 12 weeks. AP was induced
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7.5 to 11.5 year Follow Up of the Fracture Removal Treatment for Propagated Crown Fractures J. Endod. (IF 4.2) Pub Date : 2024-01-24 Philip L. Michaelson
Introduction A definitive method to predictably treat propagated longitudinal fractures remains elusive. A proof-of-concept case report series documenting nonsurgical removal of propagated longitudinal fractures has shown up to five years of clinical and radiographic success. This installment of the case report series further documents these teeth with 7.5 year to 11.5 year recall evaluations. Methods
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The Impact of Coronal Flaring Files on Pericervical Dentin Thickness in Mandibular Molars J. Endod. (IF 4.2) Pub Date : 2024-01-24 Öznur Sariyilmaz, Rüya Sessiz, Osman Sefa Kocaman
Introduction This study aimed to assess the influence of different coronal flaring files on dentin removal in mandibular teeth using CBCT images. Methods CBCT images of 48 mandibular molar teeth were acquired and randomly divided into two main groups, with each main group further divided into three subgroups. In the first main group, root canal preparation was performed using TruNatomy, ProTaper Gold
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Impact of Type 2 Diabetes Mellitus on the Occurrence of Vertical Root Fracture: A Case Control Study. J. Endod. (IF 4.2) Pub Date : 2024-01-24 PradeepKumar AngambakkamRajasekaran, JothiLatha Sundaramurthy, Archana Durvasulu, Lavanya Muralidhar, Jeffery Vimalesh, Shereen Judith, Anil Kishen
Introduction The aim of this case–control study was to examine the relationship between type 2 diabetes mellitus (DM) and the occurrence of VRFs. The crack extension, dentin sclerosis and chemical characteristics of root dentin in teeth with VRF from patients with / without DM were also compared. Methods One hundred and thirty-two patients diagnosed with VRF in crowned root filled posterior teeth were
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Flatsonic Ultrasonic Tip Optimizes the Removal of Remaining Filling Material in Flattened Root Canals. A Micro-CT Analysis J. Endod. (IF 4.2) Pub Date : 2024-01-24 Airton Oliveira Santos-Junior, Karina Ines Medina Carita Tavares, Jáder Camilo Pinto, Fernanda Ferrari Esteves Torres, Juliane Maria Guerreiro-Tanomaru, Mário Tanomaru-Filho
Introduction The aim of this study was to evaluate the effectiveness of XP-endo Finisher R (XPFR, FKG Dentaire, La Chaux-de-Fonds, Switzerland) or Flatsonic ultrasonic tip (Helse Ultrasonic, Santa Rosa de Viterbo, SP, Brazil) in removing the remaining filling material after retreatment of flattened root canals by using micro-computed tomography (micro-CT). Methods Twenty-four flattened distal root
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Bone resorption in apical periodontitis enhanced by cigarette smoke inhalation: histometric, immunohistochemical and microtomographic analysis in rats J. Endod. (IF 4.2) Pub Date : 2024-01-23 Ana Maria Veiga Vasques, Ana Claudia Rodrigues da Silva, Carlos Roberto Emerenciano Bueno, Marco Antonio Hungaro Duarte, Edilson Ervolino, Luciano Tavares Angelo Cintra, Eloi Dezan Junior
Introduction This study evaluates the effects of cigarette smoke inhalation (CSI) on apical periodontitis (AP) induced in rats by histometric, immunohistochemical, and microtomographic analysis. Methods A total of 32 male Wistar rats were divided into four experimental groups (n=8): C (control), CSI, AP and CSI+AP. Rats in the CSI and CSI+AP groups inhaled cigarette smoke by remaining inside a smoking
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Efficacy of the TuttleNumbNow Intraosseous Method for Pulpal Anesthesia in the Mandibular First Molar - A Prospective, Randomized, Crossover Study J. Endod. (IF 4.2) Pub Date : 2024-01-23 Tyler Dolphin, Sara Fowler, Melissa Drum, John Nusstein, Al Reader, John Draper
Introduction Previous studies on intraosseous (IO) anesthesia as a primary injection have shown high success rates. The TuttleNumbNow (TNN) is a new primary IO injection technique that has not been scientifically evaluated. Therefore, the purpose of this prospective randomized, crossover, study was to evaluate the anesthetic efficacy of the TNN IO technique using the Septoject Evolution needle when
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Photoinactivation of Enterococcus faecalis biofilm: In vitro antimicrobial effect of photoexcited Rutin-Gallium(III) complex via visible blue light J. Endod. (IF 4.2) Pub Date : 2024-01-23 Maryam Pourhajibagher, Hassan-Ali Ghafari, Rashin Bahrami, Abbas Bahador
Introduction Endodontic infection is a common problem that can result in tooth loss if not effectively treated. This study focused on investigating the use of a Rutin-Gallium(III) (Rutin-Ga(III)) complex-mediated antimicrobial photodynamic therapy (aPDT) for the photoinactivation of E. faecalis biofilm. Methods The minimum biofilm eradication concentration (MBEC) of Rutin-Ga(III) complex and minimum
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Allogeneic bone marrow mesenchymal stromal cell transplantation induces dentin pulp complex-like formation in immature teeth with pulp necrosis and apical periodontitis J. Endod. (IF 4.2) Pub Date : 2024-01-17 Jose Francisco Gomez-Sosa, José E. Cardier, Olga Wittig, Dylana Díaz-Solano, Eloisa Lara, Kharelys Duque, Giselle Ramos-González
Introduction Dental pulp regeneration is challenging in endodontics. Cellular therapy is an alternative approach to induce dental pulp regeneration. Mesenchymal stromal cells (MSCs) have the capacity to induce dental pulp-like tissue formation. In this study, we evaluate the capacity of allogeneic bone marrow MSCs (BM-MSCs) to regenerate pulp following necrosis and apical periodontitis in children’s
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Characterization and assessment of physical properties of three single syringe hydraulic cement-based sealers J. Endod. (IF 4.2) Pub Date : 2024-01-14 Veksina Raman, Josette Camilleri
Introduction A number of sealers with different chemistries are badged as Bioceramic implying biological activity but have dissimilar properties which has implications on the sealer properties and will affect the quality and outcome of root canal treatment. This study aims to assess the physical and chemical properties of three hydraulic cement-based sealers namely - BC Universal sealer, compared to
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Insights into the February 2024 Issue of the Journal of Endodontics J. Endod. (IF 4.2) Pub Date : 2024-01-14 Anita Aminoshariae, Amir Azarpazhooh, Ashraf F. Fouad, Gerald N. Glickman, Jianing He, Sahng G. Kim, Anil Kishen, Ariadne M. Letra, Linda Levin, Frank C. Setzer, Franklin R. Tay, Kenneth M. Hargreaves
Abstract not available
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Senescence on dental pulp cells: effects on morphology, migration, proliferation, and immune response J. Endod. (IF 4.2) Pub Date : 2024-01-09 Jade Ormondes de Farias, Maurício Gonçalves da Costa Sousa, Danilo César Mota Martins, Mayara Alves de Oliveira, Isadora Takahashi, Larissa Barbosa de Sousa, Ingrid Gracielle Martins da Silva, José Raimundo Corrêa, Amandda Évelin Silva Carvalho, Felipe Saldanha Araújo, Taia Maria Berto Rezende
Introduction Evidence indicates that senescence can affect essential dental pulp functions, such as defense capacity and repair, consequently affecting the successes of conservative endodontic treatments. This study aims to evaluate the effects of senescence on the morphology, migration, proliferation, and immune response of human dental pulp cells. Methods Cells were treated with doxorubicin to induce
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Radiographic Criteria for Differential Diagnosis between Vertical Root Fracture and Apical Periodontitis in Single-Rooted Endodontically Treated Premolars using Cone-Beam Computed Tomography J. Endod. (IF 4.2) Pub Date : 2024-01-05 Anastasia Arkhipova, Nadezhda Bovanova, Dmitrii Lastovichek, Alla Ramonova, Evgenii Generalov, Svetlana Byakova
Introduction This study explores the differences between the patterns of bone defects associated with vertical root fracture (VRF) and apical periodontitis (AP) in single-rooted endodontically treated premolars (SRETPs) based on cone-beam computed tomography (CBCT) data. Methods Eighty-four SRETPs were extracted and categorized into the VRF and AP groups. On preoperative CBCT images, the location of
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The effect of calcium hydroxide pastes on isolated vital nerve fibers J. Endod. (IF 4.2) Pub Date : 2024-01-06 Dwight D. Rice, Anupama Grandhi, Gina Delia Roque-Torres, Udochukwu Oyoyo, Leif K. Bakland
Abstract not available
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Antibiotic resistance profile of clinical strains of Enterococci from secondary/persistent endodontic infections: What do we know? A systematic review of clinical studies J. Endod. (IF 4.2) Pub Date : 2024-01-01 Marlos Barbosa-Ribeiro, Brenda P.F. A. Gomes, Rodrigo Arruda-Vasconcelos, Igor de Albuquerque Monteiro, Moan Jéfter Fernandes Costa, Pedro Henrique Sette-de-Souza
Background Enterococcus faecalis is the most common enterococcal species associated with infective endocarditis and one of the most commonly detected bacteria in cases of secondary/persistent endodontic infection (SPEI). Antimicrobial resistance is a global public health concern. Objective This review aimed to answer the following research question: “Is there a change in the antibiotic resistance profile
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The Outcomes of Endodontically Treated Teeth Restored with Custom-Made Cast Post-and-Core Restorations: A Retrospective Cohort Study J. Endod. (IF 4.2) Pub Date : 2023-12-27 A. Ben Suleiman, S. Desai, A. Tepperman, D. Chvartszaid, G. Malkhassian, E. Habsha, I. Barzilay, A. Azarpazhooh
Introduction Custom-made cast post-and-core (CMCPC) restorations have long been used to restore structurally deficient endodontically treated teeth (ETT). However, the evidence regarding their impact on the outcomes of ETT is largely inconclusive. This study evaluated the long-term treatment outcome of ETT restored with CMCPC. Methods This retrospective cohort study examined the dental records of patients
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Success in Tooth Bud Regeneration - A Short Communication J. Endod. (IF 4.2) Pub Date : 2023-12-27 Maryam Jalili Sadrabad, Elham Saberian, Armin Izadi, Rahele Emami, Farid Ghadyani
Introduction Tooth caries and loss are frequent clinical diseases in dentistry. Tissue engineering (TE) is a new therapeutic choice for the complete biological regeneration of pulpal and dental tissues in regenerative dentistry. The aim of this study was to establish a protocol for in-situ regeneration of dental bud in the extracted socket. Materials and Methods Current study examined tooth bud regeneration
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Expression of selected inflammatory mediators with different clinical characteristics of pulpal inflammation J. Endod. (IF 4.2) Pub Date : 2023-12-24 Mohammad A. Sabeti, Keyvan Nikghalb, Reza Pakzad, Ashraf Fouad
Introduction Accurately diagnosing the state of dental pulp is crucial when addressing tooth pain to determine the best treatment approach. This study aimed to investigate the concentration of inflammatory mediators in the dental pulp of mature teeth that have been exposed via caries but show no signs of apical periodontitis. Methods Samples of pulpal blood from adults with mature teeth responsive
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Evaluation of the ability of three reciprocating instruments to remove obturation material: micro- CT study J. Endod. (IF 4.2) Pub Date : 2023-12-24 Fábio Luiz Cecagno, Alexandre Sigrist De Martin, Carlos Eduardo Fontana, Bruno Cavalini Cavenago, Wayne Martins Nascimento, Ana Grasiela da Silva Limoeiro, Carlos Eduardo da Silveira Bueno
Introduction The purpose of this study was to evaluate the ability of the Reciproc, Reciproc Blue, and WaveOne Gold systems to remove filling material during endodontic retreatment of extracted human mandibular premolars. Materials and Methods Thirty-nine teeth were instrumented with the Protaper Universal System to the F3 file and filled with the Tagger Hybrid technique using an F3 gutta-percha cone
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Cell-Based Regenerative Endodontics for the Treatment of Irreversible Pulpitis: An In Vivo Investigation J. Endod. (IF 4.2) Pub Date : 2023-12-23 Mohammad A. Sabeti, Mohammad Saqib Ihsan, Dina Adami, Seyedeh-Nafiseh Hassani, Siavash Moushekhian, Reihaneh Shafieian, Hamideh Salari Sedigh, Jamileh Ghoddusi
Introduction This study aims to investigate the ability of umbilical cord mesenchymal stem cells (UC-MSC) to enhance the regeneration of pulp-dentin complex in immature permanent teeth with irreversible pulpitis. Methods A total of 32 mandibular premolar teeth with immature apices in 5 dogs were used in this in-vivo randomized controlled trial. Eight healthy teeth without pre-existing pathosis served