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Targeted augmented reality-guided transperineal prostate biopsies study: initial experience Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-03-08 Shenthiuiyan Theivendrampillai, Bob Yang, Mark Little, Christopher Blick
Background:Transperineal biopsy of magnetic resonance imaging (MRI)-detected prostate lesions is now the established technique used in prostate cancer (CaP) diagnostics. Virtual Surgery Intelligence (VSI) Holomedicine by Apoqlar (Hamburg, Germany) is a mixed reality (MR)/augmented reality (AR) software platform that runs on the HoloLens II system (Microsoft, Redford, USA). Multiparametric prostate
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The incidence, pathogenesis, and management of non-clear cell renal cell carcinoma Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-02-29 Priyanka Naik, Harshitha Dudipala, Yu-Wei Chen, Brent Rose, Aditya Bagrodia, Rana R. McKay
Renal cell carcinoma (RCC) is the most common type of kidney cancer and is divided into two distinct subtypes, clear cell renal cell carcinoma (ccRCC) and non-clear cell renal cell carcinoma (nccRCC). Although many treatments exist for RCC, these are largely based on clinical trials performed in ccRCC and there are limited studies on the management of nccRCC. Non-clear cell RCC consists of multiple
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Carboplatin in metastatic castration-resistant prostate cancer patients with molecular alterations of the DNA damage repair pathway: the PRO-CARBO phase II trial Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-02-28 Elodie Coquan, Nicolas Penel, Justine Lequesne, Raphaël Leman, Pernelle Lavaud, Zoé Neviere, Pierre-Emmanuel Brachet, Emeline Meriaux, Aurélien Carnot, Jérémy Boutrois, Marie Castera, Nicolas Goardon, Etienne Muller, Alexandra Leconte, Antoine Thiery-Vuillemin, Bénédicte Clarisse, Florence Joly
Introduction:DNA damage repair genes are altered in 20–35% of metastatic castration-resistant prostate cancer (mCRPC). Poly-ADP (Adénosine Diphosphate)-ribose polymerase inhibitors (PARPi) showed significant activity for these selected tumors, especially with homologous recombination repair (HRR) deficiency. These alterations could also predict platinum sensitivity. Although carboplatin was inconclusive
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Is suction the future of endourology? Overview from EAU Section of Urolithiasis Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-02-22 Victoria Jahrreiss, Carlotta Nedbal, Daniele Castellani, Vineet Gauhar, Christian Seitz, Guohua Zeng, Patrick Juliebø-Jones, Etienne Keller, Lazaros Tzelves, Rob Geraghty, Karan Rangarajan, Olivier Traxer, Joe Philip, Andreas Skolarikos, Panagiotis Kallidonis, Ewa Bres-Niewada, Bhaskar Somani
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Formation of vesicovaginal fistula after modified McDonald cerclage placement: a case report with literature review Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-02-22 Deama AlGhamdi, Samera F. AlBasri
Cervical cerclage is a common procedure employed to prevent preterm birth in women with cervical insufficiency. Complications such as injuries to the cervix and bladder, and premature membrane rupture are well-documented, while genitourinary fistulas are a rare occurrence. This article reports a rare case of vesicovaginal fistula (VVF) formation in a 27-year-old woman following the placement of a McDonald
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The impact of prognostic group classification on prostate cancer progression in intermediate-risk patients according to the European Association of Urology system: results in 479 patients treated with robot-assisted radical prostatectomy at a single tertiary referral center Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-02-12 Antonio Benito Porcaro, Alberto Bianchi, Andrea Panunzio, Sebastian Gallina, Alessandro Tafuri, Emanuele Serafin, Rossella Orlando, Giovanni Mazzucato, Stefano Vidiri, Damiano D’Aietti, Francesca Montanaro, Giulia Marafioti Patuzzo, Francesco Artoni, Alberto Baielli, Francesco Ditonno, Riccardo Rizzetto, Alessandro Veccia, Alessandra Gozzo, Vincenzo De Marco, Matteo Brunelli, Maria Angela Cerruto,
Background:Treatment outcomes in intermediate-risk prostate cancer (PCa) may be impaired by adverse pathology misclassification including tumor upgrading and upstaging. Clinical predictors of disease progression need to be improved in this category of patients.Objectives:To identify PCa prognostic factors to define prognostic groups in intermediate-risk patients treated with robot-assisted radical
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Current role of intraoperative cell salvage techniques in the management of renal tumors with level III and IV inferior vena cava thrombus extension Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-02-08 Cristian Surcel, Robert Dotzauer, Cristian Mirvald, Calin Popa, Cosmin Olariu, Catalin Baston, Mihai Harza, Constantin Gangu, Igor Tsaur, Ioanel Sinescu
Background:En bloc removal of the kidney with tumor thrombus excision in a multidisciplinary team remains the standard treatment for renal cell carcinoma (RCC) with tumor thrombus extension. In order to minimize the hemodynamic impact of the surgical blood loss, intraoperative cell salvage (IOCS) techniques can decrease the need for allogeneic blood and prevent blood transfusion related complications
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Oncological outcomes in robot-assisted radical prostatectomy: the value of PSA density as a preoperative predictive factor Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-02-08 Roser Vives Dilme, Juan Gómez Rivas, Laura Fernández Hernández, Irene De la Parra Sánchez, Rafael Sánchez del Hoyo, María Isabel Galante Romo, Enrique Redondo González, José Luis Senovilla Pérez, Lorena Fernández Montarroso, Jesús Moreno Sierra
Background:Pretreatment assessment of patients diagnosed with localized prostate cancer (PCa) is essential for therapeutic decision-making. Currently available staging systems based on prostate-specific antigen (PSA), Gleason score, and clinical stage allow for determining the prognostic characteristics of these patients. Several studies have evaluated the preoperative use of prostate-specific antigen
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Randomized trial of mechanotherapy for the treatment of stress urinary incontinence in women Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-02-07 Nissrine Nakib, Suzette Sutherland, Kevin Hallman, Marcus Mianulli, David R Boulware
Background:Stress urinary incontinence (SUI) presents as unintentional urine leakage associated with activities. It significantly affects quality of life (QoL) and is the most common type of incontinence in women. Current treatment options, particularly non-surgical therapies, are lacking.Objective:To assess the efficacy of mechanotherapy provided by the Flyte® intra-vaginal device during pelvic floor
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Successful bladder-sparing partial cystectomy for muscle-invasive domal urothelial carcinoma with sarcomatoid differentiation: a case report Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-01-20 Mark Sultan, Ahmad Abdelaziz, Muhammed A. Hammad, Juan R. Martinez, Shady A. Ibrahim, Mahra Nourbakhsh, Ramy F. Youssef
High-grade (HG) urothelial carcinoma (UC) with variant histology has historically been managed conservatively. The presented case details a solitary lesion of muscle-invasive bladder cancer (MIBC) with sarcomatoid variant (SV) histology treated by partial cystectomy (PC) and adjuvant chemotherapy. A 71-year-old male with a 15-pack year smoking history presented after outside transurethral resection
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The natural history of benign prostatic hyperplasia-related voiding symptoms following penile prosthesis implantation Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-01-12 Raevti Bole, Prajit Khooblall, Petar Bajic
Background:There is a rising prevalence of benign prostatic hyperplasia (BPH)-related urinary symptoms along with erectile dysfunction in the aging male population. Therefore, assessment of lower urinary tract symptoms (LUTS) is advised before penile prosthesis surgery with some men requiring preoperative transurethral surgical management to reduce the risk of post-procedure complications. However
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Risk and benefits of penile length preservation techniques during penile prosthesis implantation: a systematic review by the young academic urologists sexual and reproductive health working group Ther. Adv. Urol. (IF 2.0) Pub Date : 2024-01-08 Marco Falcone, Mirko Preto, Afonso Ribeiro Morgado, Ioannis Sokolakis, Selçuk Sarıkaya, Marco Capece, Paolo Capogrosso, Celeste Manfredi, Georgios Tsampoukas, Giorgio Russo
Background:Penile shortening, frequently resulting from end-stage Peyronie’s disease (PD), has a negative impact on patients’ sexual activity and overall quality of life, especially when accompanied by Erectile dysfunction (ED). Various surgical techniques have been described to manage concomitant ED and penile shortening through penile prosthesis (PP) implantation.Objectives:To evaluate the benefits
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Association of obesity and different metabolic status with prognosis in patients with bladder cancer: a retrospective cohort study. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-11-28 Yingchun Dong,Yiping Cheng,Honglin Guo,Jiaxing Sun,Junming Han,Fang Zhong,Qihang Li,Dawei Wang,Wenbin Chen,Xiude Fan,Jiajun Zhao
Background and objectives Patients with bladder cancer (BC) are at high risk for recurrence rates and readmission costs. However, the evidence about obesity and metabolic abnormalities on the BC prognosis was inconsistent. Our primary aim was to determine the impact of obesity and different metabolic status on the readmission risk in patients with BC. Design and methods We identified 16,649 patients
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CO2 laser therapy for management of stress urinary incontinence in women: a systematic review and meta-analysis. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-11-10 Bandr Hafidh,Saeed Baradwan,Hassan M Latifah,Abdulrahim Gari,Hussein Sabban,Hanin Hassan Abduljabbar,Afaf Tawfiq,Ghaidaa Farouk Hakeem,Alya Alkaff,Nabigah Alzawawi,Radiah Iskandarani,Kausar Khurshid,Kausar Aisha Syed,Ammar Y Alkhiary,Ibtihal Abdulaziz Bukhari,Maha Al Baalharith,Ahmed Abu-Zaid
Background Carbon dioxide (CO2) laser therapy is an emerging treatment for women with stress urinary incontinence (SUI). Objectives To examine the efficacy of CO2 laser therapy for management of SUI-related symptoms in women. Design A systematic review and meta-analysis of randomized controlled trials and cohort studies. Data sources and methods Four databases were screened until January 2023. All
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Observational study on the evolution of systemic treatments for advanced renal cell carcinoma in Southwest Finland between 2010 and 2021. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-11-05 Olivia Hölsä,Kaisa Teittinen,Anna Anttalainen,Liisa Ukkola-Vuoti,Milla Summanen,Kalle E Mattila
Background Novel receptor tyrosine kinase inhibitors and immune checkpoint inhibitors have been introduced to the treatment of advanced renal cell carcinoma (aRCC) during the past decade. However, the adoption of novel treatments into clinical practice has been unknown in Finland. Objectives Our aim was to evaluate the use of systemic treatments and treatment outcomes of aRCC patients in Southwest
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The implications when offering percutaneous nephrostomy for the management of malignant obstructive uropathy secondary to urological malignancy: can we be more selective? Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-10-27 Elizabeth Osinibi,Hong Doan,Alejandro Mercado-Campero,Jayasimha Abbaraju,Shikohe Masood,Sanjeev Madaan
Background & Objectives Percutaneous nephrostomy (PN) for malignant ureteric obstruction (MUO) is increasingly accessible with high success rates. However, it is not without associated risks and morbidity, impacting quality of life, while not improving overall survival. In two UK hospitals, we investigated the outcomes of undergoing PN for MUO, to inform future patient counselling and selection for
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Outcome following the surgical management of varicocele in children and adolescents: a systematic review and meta-analysis. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-10-20 Sarthak Tandon,Daniel Bennett,Ramesh Mark Nataraja,Maurizio Pacilli
Background The ideal surgical approach for the management of varicocele in children and adolescents remains controversial. Several techniques are available including artery- or lymphatic-sparing with optical magnification (via open inguinal or sub-inguinal approach), laparoscopic, antegrade and retrograde embolization/sclerotherapy. Objectives We aimed to appraise the clinical outcomes of these techniques
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Chronic scrotal content pain: the experiences of patients undergoing microsurgical spermatic cord denervation. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-09-25 Davina Banner,Darby Cassidy,Colin Appleby,Shayna Dolan,Shannon Freeman,Tammy Klassen-Ross,Kiranpreet Ghag
Background Chronic scrotal content pain, sometimes referred to as chronic orchialgia, is a common urological condition that gives rise to persistent and often severe painful stimuli to the scrotum and surrounding structures. Despite its relative commonality, accounting for over 2% of urological visits, chronic scrotal content pain is complex to manage and patients may be required to access multiple
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Transperineal laser ablation as a new minimally invasive surgical therapy for benign prostatic hyperplasia: a systematic review of existing literature. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-09-21 Lazaros Tzelves,Santhosh Nagasubramanian,Alexandros Pinitas,Patrick Juliebø-Jones,Sanjeev Madaan,Giampaolo Sienna,Bhaskar Somani
Introduction Transperineal laser ablation (TPLA) of the prostate is a new, minimally invasive technique for benign prostatic hyperplasia (BPH) with promising effectiveness and safety outcomes. This systematic review aims to provide an update of existing literature. Methods A literature review was performed in Pubmed/MEDLINE, Embase, Cochrane Library, and clinicaltrials.gov from January 2000 up to April
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Insertion of inflatable penile prosthesis in the neophallus of assigned female at birth individuals: a systematic review of surgical techniques, complications and outcomes. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-09-14 Karl H Pang,Nim Christopher,David J Ralph,Wai Gin Lee
Devices such as inflatable penile prostheses (IPP) can be used to achieve erectile rigidity after phalloplasty in assigned female at birth (AFAB) individuals. The approach to inserting an IPP in a neophallus is different and more challenging compared to that of an anatomical penis due to the absence of anatomical structures such as the corpora cavernosa, and the more tenuous blood supply of the neophallus
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Does unenhanced computerized tomography as imaging standard post-retrograde intrarenal surgery paradoxically reduce stone-free rate and increase additional treatment for residual fragments? Outcomes from 5395 patients in the FLEXOR study by the TOWER group. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-09-08 Vineet Gauhar,Daniele Castellani,Ben Hall Chew,Daron Smith,Chu Ann Chai,Khi Yung Fong,Jeremy Yuen-Chun Teoh,Olivier Traxer,Bhaskar Kumar Somani,Thomas Tailly
Background Assessment of residual fragments (RFs) is a key step after treatment of kidney stones. Objective To evaluate differences in RFs estimation based on unenhanced computerized tomography (CT) versus X-rays/ultrasound after retrograde intrarenal surgery (RIRS) for kidney stones. Design A retrospective analysis of data from 20 centers of adult patients who had RIRS was done (January 2018-August
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The role of 'artificial intelligence, machine learning, virtual reality, and radiomics' in PCNL: a review of publication trends over the last 30 years. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-09-08 Carlotta Nedbal,Clara Cerrato,Victoria Jahrreiss,Daniele Castellani,Amelia Pietropaolo,Andrea Benedetto Galosi,Bhaskar Kumar Somani
Introduction We wanted to analyze the trend of publications in a period of 30 years from 1994 to 2023, on the application of 'artificial intelligence (AI), machine learning (ML), virtual reality (VR), and radiomics in percutaneous nephrolithotomy (PCNL)'. We conducted this study by looking at published papers associated with AI and PCNL procedures, including simulation training, with preoperative and
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Variation of diagnosis and treatment of catheter-associated urinary tract infections: an online survey among caretakers involved. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-09-06 Tess van Doorn,Sophie A Berendsen,Rosa L Coolen,Jeroen R Scheepe,Bertil F M Blok
Background The diagnosis of a clinically significant catheter-associated urinary tract infection (CAUTI) in patients performing clean intermittent catheterization (CIC) or with an indwelling catheter (IC) can be challenging. Objective To get an insight into the variation of the used definition, diagnosis and management of CAUTIs by relevant healthcare workers in the Netherlands. Design An online clinical
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The outcomes of penile prosthesis in neurologic patients: a multicentric retrospective series. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-08-31 Marco Falcone,Paolo Capogrosso,Lorenzo Cirigliano,Paolo Geretto,Mirko Preto,Massimiliano Timpano,Carlo Ceruti,Federica Peretti,Ilaria Ferro,Natalia Plamadeala,Federico Dehò,Carlo Bettocchi,Celeste Manfredi,Lorenzo Spirito,Alessandro Palmieri,Alberto Manassero,Gideon Blecher,Paolo Gontero
Introduction Neurological disease is a known entity for causing erectile dysfunction (ED). Pharmacological therapies are not always effective these patients - penile prosthesis implant (PPI) is an established surgical treatment option. For a variety of reasons, neurological patients may experience differing outcomes of PPI compared to those whose ED arises from other causes. We investigated outcomes
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Preoperative predictors of prolonged length of stay in radical cystectomy: a retrospective study using the American College of Surgeons-National Surgical Quality Improvement Program Dataset. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-08-10 Elia Abou Chawareb,Christian Habib Ayoub,Jad Najdi,Joseph Ghoubaira,Albert El-Hajj
Background Radical cystectomy (RC) is considered a complex procedure that entails significant morbidity and mortality. Objectives We aimed to determine pre-operative patient characteristics that help predict a prolonged length of hospital stay (PLOS) following RC. Design and Methods The American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP) database was used to select
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Simulation-based education in urology - an update. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-08-10 Angus Ritchie,Maurizio Pacilli,Ramesh M Nataraja
Over the past 30 years surgical training, including urology training, has changed from the Halstedian apprenticeship-based model to a competency-based one. Simulation-based education (SBE) is an effective, competency-based method for acquiring both technical and non-technical surgical skills and has rapidly become an essential component of urological education. This article introduces the key learning
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Contemporary male slings for stress urinary incontinence: advances in device technology and refinements in surgical techniques. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-07-25 Eric Chung
Synthetic male sling (MS) is considered an effective surgical treatment to restore male stress urinary incontinence. The modern MS can be categorised into adjustable or non-adjustable types, while the surgical techniques can be divided into retropubic or transobturator approaches. This narrative review paper evaluates the contemporary MS devices in the current commercial market regarding clinical outcomes
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The role of mean corpuscular volume and red cell distribution width in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors: the MARECAP retrospective study. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-07-22 Chiara Tommasi,Giulia Scartabellati,Diana Giannarelli,Ugo De Giorgi,Nicole Brighi,Giuseppe Fornarini,Sara Elena Rebuzzi,Silvia Puglisi,Orazio Caffo,Stefania Kinspergher,Alessia Mennitto,Carlo Cattrini,Matteo Santoni,Elena Verzoni,Alessandro Rametta,Marco Stellato,Andrea Malgeri,Giandomenico Roviello,Matteo Brunelli,Sebastiano Buti
Background Tyrosine-kinase inhibitors (TKIs) and immunotherapy represent the backbone treatment for metastatic renal cell carcinoma (mRCC) patients. The aim of the present study was to describe mean corpuscular volume (MCV) and red cell distribution width (RDW) in mRCC patients treated with pazopanib or cabozantinib, and to explore their potential impact on oncological outcomes. Materials and methods
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State-of-art review of current malleable penile prosthesis devices in the commercial market. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-07-14 Eric Chung,Juan Wang
The malleable penile implant is often considered an inferior device to the three-piece inflatable penile prosthesis implant. Nonetheless, the malleable prosthesis has its unique advantages such as lower cost, easier to perform and fewer mechanical complications than inflatable prostheses. Furthermore, its role can be extended to patients with issues relating to poor manual hand dexterity, those undergoing
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A scoping review of tissue interposition flaps used in vesicovaginal fistulae repair. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-06-26 Halime Serinçay,Hayrullah Uğur Güler,Kezban Ulubayram,Naşide Mangır
Background Research on the use of tissue interposition flaps (TIFs) in vesicovaginal fistulae (VVF) repair is a broad area where a very wide range of natural and synthetic materials have been used. The occurrence of VVF is also diverse in the social and clinical settings, resulting in a parallel heterogeneity in the published literature on its treatment. The use of synthetic and autologous TIFs in
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Instrumental dead space and proximal working channel connector design in flexible ureteroscopy: a new concept. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-06-24 Jia-Lun Kwok,Vincent De Coninck,Amelia Pietropaolo,Patrick Juliebø-Jones,Eugenio Ventimiglia,Thomas Tailly,Florian Alexander Schmid,Manuela Hunziker,Cédric Poyet,Olivier Traxer,Daniel Eberli,Etienne Xavier Keller
Objective The objective of this study was to evaluate a new concept in flexible ureteroscopy: instrumental dead space (IDS). For this purpose, various proximal working channel connector designs, as well as the impact of ancillary devices occupying the working channel were evaluated in currently available flexible ureteroscopes. Design and methods IDS was defined as the volume of saline irrigation needed
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Multidisciplinary treatment (MDT) perspectives in renal cell carcinoma. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-06-19 Jeanny B Aragon-Ching,Robert Uzzo
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Patterns of use of medications used to treat urinary incontinence and potentially inappropriate prescriptions. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-06-16 Luis Fernando Valladales-Restrepo,Hugo Alejandro Bedoya-Arias,Brayan Stiven Aristizábal-Carmona,Jorge Enrique Machado-Alba
Background The pharmacological treatment of urinary incontinence (UI) may involve bladder antimuscarinics, which can generate risks in the elderly. Objective The aim was to determine the treatment patterns of a group of patients with UI and possible potentially inappropriate prescriptions. Design and methods This was a cross-sectional study that identified prescription patterns of medications for outpatient
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Bispecific PSMA antibodies and CAR-T in metastatic castration-resistant prostate cancer. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-06-15 Kevin K Zarrabi,Vivek Narayan,Patrick J Mille,Matthew R Zibelman,Benjamin Miron,Babar Bashir,William Kevin Kelly
Prostate cancer is the most common cancer among men and the second leading cause of cancer-related deaths in men in the United States. The treatment paradigm for prostate cancer has evolved with the emergence of a variety of novel therapies which have improved survival; however, treatment-related toxicities are abundant and durable responses remain rare. Immune checkpoint inhibitors have shown modest
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Under pressure: irrigation practice patterns during flexible ureteroscopy. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-06-13 Bassel Salka,Jamsheed Bahaee,Jeff Plott,Khurshid R Ghani
Introduction Irrigation parameters during flexible ureteroscopy (fURS) may impact patient outcomes, yet there are limited data on current practice patterns of irrigation methods and parameter selection. We assessed the common irrigation methods, pressure settings, and situations that present the most problems with irrigation among worldwide endourologists. Methods A questionnaire on fURS practice patterns
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Single-port robotic partial nephrectomy: impact on perioperative outcomes and hospital stay. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-06-06 Umberto Carbonara,Daniele Amparore,Leonardo D Borregales,Anna Caliò,Chiara Ciccarese,Pietro Diana,Selcuk Erdem,Laura Marandino,Michele Marchioni,Constantijn H J Muselaers,Carlotta Palumbo,Nicola Pavan,Angela Pecoraro,Eduard Roussel,Hannah Warren,Zhen-Jie Wu,Riccardo Campi,Riccardo Bertolo
Single-port (SP) robotic surgery is a novel technology and is at the beginning of its adoption curve in urology. The goal of this narrative review is to provide an overview of SP-robotic partial nephrectomy (PN) 4 years after the introduction of the da Vinci SP dedicated platform, focusing on perioperative outcomes, length of stay, and surgical technique. A nonsystematic review of the literature was
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New multiport robotic surgical systems: a comprehensive literature review of clinical outcomes in urology. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-06-05 Morgan Salkowski,Enrico Checcucci,Alexander K Chow,Craig C Rogers,Firas Adbollah,Evangelos Liatsikos,Prokar Dasgupta,Gustavo C Guimaraes,Jens Rassweiler,Alexander Mottrie,Alberto Breda,Simone Crivellaro,Jihad Kaouk,Francesco Porpiglia,Riccardo Autorino
Over the past 20 years, the field of robotic surgery has largely been dominated by the da Vinci robotic platform. Nevertheless, numerous novel multiport robotic surgical systems have been developed over the past decade, and some have recently been introduced into clinical practice. This nonsystematic review aims to describe novel surgical robotic systems, their individual designs, and their reported
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Robotic-assisted radical prostatectomy is pushing the boundaries: a national survey of frailty using the national surgical quality improvement program. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-06-03 Nassib F Abou Heidar,Christian Habib Ayoub,Anthony Abou Mrad,Jad Abdul Khalek,Hani Tamim,Albert El-Hajj
Background Robotic-assisted radical prostatectomy (RARP) has been found to be comparable and, in some cases, favorable to open surgical approaches, while being used in a frailer population. Objectives We aimed to illustrate the trend in population frailty and compare morbidity and mortality postoperatively in patients who underwent RARP. Design and Methods The National Surgical Quality Improvement
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Percutaneous tibial nerve stimulation in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients: a historically controlled study. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-05-30 Marco Carilli,Patrizio Pacini,Maurizio Serati,Valerio Iacovelli,Daniele Bianchi,Filomena Petta,Serena Pastore,Ivana Amato,Claudia Fede Spicchiale,Giulia D'Ippolito,Simone Pletto,Yuri Cavaleri,Andrea D'Amico,Isabella Parisi,Enrico Finazzi Agrò
Background Percutaneous tibial nerve stimulation (PTNS) is widely used in the treatment of neurogenic detrusor overactivity (NDO) in multiple sclerosis (MS); however, controlled studies are still lacking.Objective:: To assess effectiveness of PTNS in MS patients with NDO unresponsive to pharmacological and behavioural therapies. Methods MS patients with NDO were enrolled. Inclusion criteria were NDO
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Current state of mobile health apps in endourology: a review of mobile platforms in marketplaces and literature. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-05-29 Ali Talyshinskii,Guliev Bakhman,Bm Zeeshan Hameed,Amelia Pietropaolo,Nithesh Naik,Bhaskar K Somani
Several mobile healthcare (mHealth) apps are available in various marketplaces, but there is still concern about their accuracy, data safety, and regulation. The goal of this review was to critically analyze the mobile apps created for education, diagnosis, and medical and surgical treatment of patients with kidney stone disease (KSD), as well as to assess the level of data security, the contribution
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The effect of ureteropelvic junction obstruction and pyeloplasty on somatic growth during infancy. Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-05-19 Eyal Kord,Binyamin B Neeman,Dolev Perez,Boris Chertin,Amnon Zisman,Amos Neheman
Background Evidence regarding the impact of perinatal ureteropelvic junction obstruction (UPJO) and surgical correction during infancy, on somatic growth are scarce. Understanding these impacts could help advise parents and aid in treatment decision making. Objectives To assess the impact of unilateral UPJO and surgical correction on somatic growth in infants diagnosed antenatally and treated during
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Concurrent radical cystectomy and nephroureterectomy indications and outcomes: a systematic review and comparative analysis Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-05-09 Marwan Zein, Ali A. Nasrallah, Nassib F. Abou Heidar, Jad Najdi, Layal Hneiny, Albert El Hajj
Introduction:Urothelial carcinoma can arise from the urinary bladder or from the upper urinary tract. In some instances, urinary bladder cancer (UBC) and upper tract urothelial carcinoma (UTUC) can...
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Artificial intelligence and radiomics in evaluation of kidney lesions: a comprehensive literature review Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-04-17 Matteo Ferro, Felice Crocetto, Biagio Barone, Francesco del Giudice, Martina Maggi, Giuseppe Lucarelli, Gian Maria Busetto, Riccardo Autorino, Michele Marchioni, Francesco Cantiello, Fabio Crocerossa, Stefano Luzzago, Mattia Piccinelli, Francesco Alessandro Mistretta, Marco Tozzi, Luigi Schips, Ugo Giovanni Falagario, Alessandro Veccia, Mihai Dorin Vartolomei, Gennaro Musi, Ottavio de Cobelli, Emanuele
Radiomics and artificial intelligence (AI) may increase the differentiation of benign from malignant kidney lesions, differentiation of angiomyolipoma (AML) from renal cell carcinoma (RCC), differe...
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Cytomegalovirus haemorrhagic cystitis in a pregnant patient with AIDS Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-03-22 Bernard Marais, Veena John, Mariëtte Du Toit, Jeanne Mbambo, Jeff John
Cytomegalovirus (CMV), an AIDS defining disease, has a high seroprevalence in the general population, while symptomatic infections occur mostly in immunocompromised individuals. Symptomatic CMV inf...
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Management of the urological tract in children with anorectal malformations – a contemporary review Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-03-21 Kelly T. Harris, Duncan T. Wilcox
Anorectal malformations (ARMs) consist of a broad spectrum of congenital anomalies that are associated with an equally wide variety of urological abnormalities, often with increasing incidence as t...
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Paediatric kidney stone surgery: state-of-the-art review Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-03-18 Patrick Juliebø-Jones, Etienne Xavier Keller, Lazaros Tzelves, Christian Beisland, Bhaskar K Somani, Peder Gjengstø, Mathias Sørstrand Æsøy, Øyvind Ulvik
While urolithiasis in children is rare, the global incidence is rising, and the volume of minimally invasive surgeries being performed reflects this. There have been many developments in the techno...
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RIRS with disposable or reusable scopes: does it make a difference? Results from the multicenter FLEXOR study Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-03-11 Vineet Gauhar, Chu Ann Chai, Ben H Chew, Abhishek Singh, Daniele Castellani, Thomas Tailly, Esteban Emiliani, William Ong Lay Keat, Deepak Ragoori, Mohamed Amine Lakmichi, Jeremy Yuen-Chun Teoh, Olivier Traxer, Bhaskar Kumar Somani
Introduction:With several single-use ureteroscopes now available, our aim was to analyze and compare data obtained globally from high-volume centers using both disposable and reusable flexible uret...
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Normal preoperative endogenous testosterone levels predict prostate cancer progression in elderly patients after radical prostatectomy Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-02-22 Antonio Benito Porcaro, Andrea Panunzio, Alberto Bianchi, Clara Cerrato, Sebastian Gallina, Emanuele Serafin, Giovanni Mazzucato, Stefano Vidiri, Damiano D’Aietti, Rossella Orlando, Davide Brusa, Matteo Brunelli, Salvatore Siracusano, Vincenzo Pagliarulo, Maria Angela Cerruto, Alessandro Tafuri, Alessandro Antonelli
Background:The impact of senior age on prostate cancer (PCa) oncological outcomes following radical prostatectomy (RP) is controversial, and further clinical factors could help stratifying risk cat...
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Report of testicular tumour in a toddler: management beyond the testis Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-02-01 Amit Sharma, Deepak Biswal, Satyadeo Sharma, Kishore Roy
Testicular tumours in prepubertal children tend to be pure yolk sac tumours detected in stage I and have good prognosis. We describe a case of a 2-year old male child with a mixed testicular tumour...
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Diagnostic and therapeutic value of biomarkers in urosepsis Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-01-31 Yuyun Wu, Guang Wang, Ziye Huang, Bowei Yang, Tongxin Yang, Jianhe Liu, Pei Li, Jiongming Li
Urosepsis is sepsis caused by urogenital tract infection and is one of the most common critical illnesses in urology. If urosepsis is not diagnosed early, it can rapidly progress and worsen, leadin...
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Sedation as an alternative anesthetic technique for frail patients in transurethral resection of the prostate Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-01-19 Christian Habib Ayoub, Viviane Chalhoub, Adnan El-Achkar, Nassib Abou Heidar, Hani Tamim, Marie Maroun-Aouad, Albert El Hajj
Background:Transurethral resection of the prostate (TURP) under Monitored Anesthesia Care MAC/Sedation (macTURP), as compared with TURP under general (genTURP) or spinal (spTURP) anesthesia, is a s...
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Insights from the AQUA Registry: a retrospective study of anticholinergic polypharmacy in the United States Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-01-19 Matthew R. Cooperberg, Rachel Mbassa, David Walker, William Meeks, Amy Lockefeer, Baoguo Jiang, Tina Li, Karissa Johnston, Raymond Fang
Background:Anticholinergic (ACH) burden is a risk factor for negative health outcomes among older adults. Several medications contribute to ACH burden, including antimuscarinics used to manage over...
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The role of switch maintenance therapy in urothelial cancers Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-01-13 Eun-mi Yu, Mythri Mudireddy, Rakesh Biswas, Jeanny B. Aragon-Ching
Maintenance therapy with immune checkpoint inhibitors (ICIs) has changed the treatment paradigm of metastatic urothelial carcinoma (mUC). The JAVELIN Bladder 100 trial established avelumab, one of ...
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Robotic-assisted simple prostatectomy: long-term, trifecta- and pentafecta-based analysis of functional outcomes Ther. Adv. Urol. (IF 2.0) Pub Date : 2023-01-12 Alfredo Maria Bove, Aldo Brassetti, Mario Ochoa, Umberto Anceschi, Marilia Ferriero, Gabriele Tuderti, Leonardo Misuraca, Riccardo Mastroianni, Silvia Cartolano, Simone D’Annunzio, Giulia Torreggiani, Giuseppe Simone
Background:Robotic-assisted simple prostatectomy (RASP) proved to be a sound and effective procedure for bladder outlet obstructive symptoms relief. Routinely, the transvesical (Freyer) or transcap...
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Multiparametric ultrasound of prostate: role in prostate cancer diagnosis Ther. Adv. Urol. (IF 2.0) Pub Date : 2022-12-26 Masatomo Kaneko, Maria Sarah L. Lenon, Lorenzo Storino Ramacciotti, Luis G. Medina, Aref S. Sayegh, Anibal La Riva Rincon, Laura C. Perez, Alireza Ghoreifi, Maria Lizana, Donya S. Jadvar, Amir H. Lebastchi, Giovanni E. Cacciamani, Andre Luis Abreu
Recent advances in ultrasonography (US) technology established modalities, such as Doppler-US, HistoScanning, contrast-enhanced ultrasonography (CEUS), elastography, and micro-ultrasound. The early...
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Outcomes of ureteroscopy for management of stone disease in early and late childhood over a 15-year period Ther. Adv. Urol. (IF 2.0) Pub Date : 2022-12-20 Mriganka Sinha, Amelia Pietropaolo, Yesica Quiroz Madarriaga, Erika Llorens de Knecht, Anna Bujons Tur, Stephen Griffin, Bhaskar K Somani
Background:Although paediatric ureteroscopy is widely performed, there is still a lack of data and outcomes in early childhood. In this two-centre study, we compared the outcomes of ureteroscopy fo...
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Midline submuscular penile prosthesis reservoir placement for patients with bilateral inaccessible inguinal rings: technique and outcomes Ther. Adv. Urol. (IF 2.0) Pub Date : 2022-12-06 Ariel Zisman, Shirin Razdan, Alexandra Siegal, Michaela Sljivich, Christine Bieber, Patrick Ho, Robert Valenzuela
Introduction:One of the most challenging aspects of inflatable penile prosthesis (IPP) surgery is reservoir placement. The traditional space of Retzius (SOR) is not suitable for all patients. For e...
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Current role of neuromodulation in bladder pain syndrome/interstitial cystitis Ther. Adv. Urol. (IF 2.0) Pub Date : 2022-11-21 Bárbara Padilla-Fernández, David Hernández-Hernández, David M. Castro-Díaz
Neuromodulation is recommended by major international guidelines as a fourth-line treatment in bladder pain syndrome/interstitial cystitis (BPS/IC) patients after failure of behavioural, oral and i...
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Preoperative MELD score predicts mortality and adverse outcomes following radical cystectomy: analysis of American College of Surgeons National Surgical Quality Improvement Program Ther. Adv. Urol. (IF 2.0) Pub Date : 2022-11-15 Christian Habib Ayoub, Ali Dakroub, Jose M. El-Asmar, Adel Hajj Ali, Hadi Beaini, Suhaib Abdulfattah, Albert El Hajj
Background:The model for end-stage liver disease (MELD) has been widely used to predict the mortality and morbidity of various surgical procedures.Objectives:We aimed to correlate a high preoperati...
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Emerging perioperative therapeutic approaches in muscle invasive bladder cancer Ther. Adv. Urol. (IF 2.0) Pub Date : 2022-10-28 Goutham Patil, Arnab Basu
Bladder cancer is a significant healthcare burden with more than 17,000 deaths in the United States in 2018. Patients who are diagnosed with muscle invasive bladder cancer (MIBC) have a high rate o...