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Metformin Regulates the miR-205/VEGFA Axis in Renal Cell Carcinoma Cells - Exploring a Clinical Synergism with Tyrosine Kinase Inhibitors. Urol. Int. (IF 1.6) Pub Date : 2023-11-30 Markus Krebs,Mischa J Kotlyar,Julian Fahl,Sudha Janaki Raman,Florian Röhrig,André Marquardt,Hubert Kübler,Burkhard Kneitz,Almut Schulze,Charis Kalogirou
INTRODUCTION Metformin (MF) intake could be associated with a favorable outcome in Sunitinib (SUT)- and Axitinib (AX)-treated clear cell renal cell carcinoma (ccRCC) patients. Functionally, MF induces miR-205, a microRNA serving as a tumor suppressor in several cancers. METHODS qRT-PCR, viability assays and Western blotting analyzed MF and SUT/AX effects in RCC4 and 786-O cells. A tetracycline-inducible
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How Much Do Altmetric Scores Correlate with Bibliometric Scores? Analysis of the Most-Cited 100 Articles about the Holmium Laser Enucleation Prostatectomy. Urol. Int. (IF 1.6) Pub Date : 2023-11-30 Gokhan Sonmez,Abdullah Golbasi
INTRODUCTION In addition to bibliometric scores, which are an indicator of academic popularity, it has become frequently used in altmetric scoring that shows the visibility of articles on social media and the internet. In this study, 100 most-cited studies on holmium laser enucleation prostatectomy (HoLEP) were examined, and it was investigated whether the number of citations per year of these studies
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: Letter to the Editor regarding the Article " Treatment of Ureteral Stent-Related Symptoms": Systematic Review. Urol. Int. (IF 1.6) Pub Date : 2023-11-30 Vilas Sabale,Vikram Satav,Prabhav Agarwal
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Correlation between prostate cancer positive cores and 68Ga-PSMA distribution in prostate gland. Urol. Int. (IF 1.6) Pub Date : 2023-11-28 Süleyman Çankaya,Ahmet Ender Caylan,Funda Aydin,Murat Uçar,Ömer Kutlu
INTRODUCTION The purpose of our study was to evaluate reliability of 68Ga-labeled prostate spesific membrane antigen positron emission tomography (68Ga-PSMA PET/CT) and identify appropriate SUVmax cut-off values in order to use for diagnosis especially in patients remained clinically suspicious for prostate cancer (PCa). METHODS Eighty-four patients applied 68Ga-PSMA PET/CT subsequent to transrectal
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The Value of the Prostate Health Index and Derived Indexes in the Diagnosis of Prostate Cancer with PI-RADS-3 Lesions. Urol. Int. (IF 1.6) Pub Date : 2023-11-27 Yang Cui,Jin Zhao,Yuan Sun
INTRODUCTION The purpose of this article was to evaluate the diagnostic value of prostate health index (PHI) and its derivatives in prostate cancer (PCa) with prostate imaging reporting and data system (PI-RADS)-3 lesions. METHODS Patients with benign prostatic hyperplasia (BPH) (n = 155) were included in the BPH group, while all patients with PCa (n = 49) were enrolled in the PCa group. Between the
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Physical techniques to remove residual stone fragments in the urinary system. Urol. Int. (IF 1.6) Pub Date : 2023-11-26 Minhua Qiu,Ting Zhang,Yingying Zhang,Taisheng Liang,Jibing Chen,Hongjun Gao
BACKGROUND Although significant progress has been made in treatment techniques for renal and ureteral calculi, residual fragments (RF) persisting long after treatment pose a serious threat to patients' health. A variety of novel physical techniques and extraction devices are currently being developed to promote the removal of RF from the urinary system, and a series of in vivo experiments have demonstrated
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Laparoscopic Radical Cystectomy With Ileal Orthotopic Neobladder for Bladder Cancer: Current Indications and Outcomes. Urol. Int. (IF 1.6) Pub Date : 2023-11-23 Lin Guo,Ting Zhang,Liang Taisheng,Jibing Chen,Hongjun Gao
BACKGROUND Laparoscopic radical cystectomy (LRC) with ileal orthotopic neobladder (IONB) reconstruction is one of the most promising methods for bladder cancer treatment; its advantages include a small incision size, less blood loss, improved perioperative outcome and tumor prognosis, and a positive self-image postoperatively. The short-term benefits of various IONB reconstruction procedures reported
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Estimated prostate volume by semiautomatic segmentation of MRI is more accurately correlated with radical prostatectomy specimen weight than the volume calculated by ellipsoid formula. Urol. Int. (IF 1.6) Pub Date : 2023-11-23 Shulin Wu,Adam S Feldman,Sharron X Lin,Michelle M Kim,Kristine M Cornejo,Mukesh G Harisinghani,Chin-Lee Wu,Douglas M Dahl
BACKGROUND Accurate in-vivo prostate volume (PV) estimation is important for obtaining prostate-specific antigen density (PSAD) and further predicting clinically significant prostate cancer (csPCa). We aimed to evaluate the accuracy of multiparametric magnetic resonance imaging (mpMRI) estimated PV compared to both volume and weight of radical prostatectomy (RP). PATIENTS AND METHODS We identified
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The Value of Prostate-Specific Antigen Density in Combination with Lesion Diameter for the Accuracy of Prostate Cancer Prediction in Prostate Imaging-Reporting and Data System 3 Prostate Lesions. Urol. Int. (IF 1.6) Pub Date : 2023-11-20 Samet Senel,Antonios Koudonas,Emre Uzun,Kazim Ceviz,Sedat Tastemur,Cuneyt Ozden,Tolga Karakan,Merve Meryem Kiran,Firathan Sarialtin,Erkan Olcucuoglu
INTRODUCTION The aim of the study was to investigate the value of prostate-specific antigen density (PSAD) and lesion diameter (LD) combination in prostate cancer (PCa) detection. METHODS 181 patients who were detected to have prostate imaging-reporting and data system (PI-RADS) 3 lesions in mpMRI and underwent prostate biopsies were included in the study. Demographic, clinical, and pathological data
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Transurethral Hem-o-lok Clip Ligation of the Distal Ureter in Retroperitoneal Laparoscopic Radical Nephroureterectomy. Urol. Int. (IF 1.6) Pub Date : 2023-11-15 Chunyang Wang,Hongkai Yu,Weijun Fu,Guangfu Chen,Shengkun Sun,Xu Zhang
BACKGROUND AND OBJECTIVE Distal ureter management is an essential part of radical nephroureterectomy (RNU). However, there is no agreement on the optimal surgical treatment for ureter and bladder cuff excision. The classical "pluck" technique following transurethral resection of the intramural ureter increases the risk of extravesical and intravesical tumor cell spillage. We aimed to provide a simple
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Upstaging after TUR-BT for non-muscle invasive cancer of the bladder - Who is at highest risk? Urol. Int. (IF 1.6) Pub Date : 2023-11-09 Yannic Volz,Rabea Trappmann,Benedikt Ebner,Lennert Eismann,Benazir Enzinger,Julian Hermanns,Nikolaos Pyrgidis,Christian Stief,Gerald B Schulz
Introduction Transurethral resection of the bladder (TUR-BT) is the standard initial treatment and diagnosis of bladder cancer (BC). Of note, upstaging into muscle-invasive disease (MIBC) during re-resection occurs in a significant proportion of patients. This study aims to define risk factors at initial TUR-BT for upstaging. Methods TUR-BT between 2009 and 2021 were retrospectively screened (n=3237)
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Comparing the effect of pre-biopsy rectal cleaning together with biopsy needle disinfection to each technique alone on hospitalization rates because of post-biopsy infections. Urol. Int. (IF 1.6) Pub Date : 2023-11-08 Coşkun Bostancı,Salih Bürlukkara
INTRODUCTION To compare the effects of three techniques: biopsy needle disinfection with 10% formalin solution, povidone-iodine rectal cleaning, and the use of both methods to decrease hospitalization due to infectious complications after transrectal prostate biopsy. METHODS A total of 827 patients were divided into 3 groups. Group 1 patient data were analyzed retrospectively, while groups 2 and 3
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Clinical effects of oral supplementation of gamma-ciclodextrin curcumin complex in male patients with moderate-to-severe BPH-related Lower Urinary Tract Symptoms. Urol. Int. (IF 1.6) Pub Date : 2023-11-08 Fabio Crocerossa,Francesco Cantiello,Lorenzo Bagalá,Francesco Sicoli,Umberto Carbonara,Celeste Manfredi,Ugo Falagario,Alessandro Veccia,Savio D Pandolfo,Luigi Napolitano,Matteo Ferro,Michele Di Dio,Nicola Mondaini,Rocco Damiano
INTRODUCTION Benign prostatic hyperplasia (BPH) is the most common cause of lower urinary tract symptoms (LUTS) in males. Curcumin exhibits anti-inflammatory and anti-tumor properties which may be effective for BPH. This multi-arm observational study evaluated the real-world efficacy of QURMIN® (Gamma-cyclodextrin-curcumin Complex-CAVACURMIN®) as single or combination therapy for BPH. METHODS Men with
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Patient Benefits of Radical Prostatectomy in Certified Prostate Cancer Centers: Comparative Results from the Multicenter IMPROVE Study. Urol. Int. (IF 1.6) Pub Date : 2023-11-06 Danijel Sikic,Christian Fiebig,Bernd Wullich,Ingmar Wolff,Bernd Hoschke,Andreas Manseck,Rolf Gillitzer,Maximilian Burger,Julie Steinestel,Nina Harke,Niklas Löbig,Florian A Distler,Matthias May,Julia Peter,Christian Gilfrich
INTRODUCTION We investigated differences in treatment outcomes following radical prostatectomy (RP) between certified centers (CCs) and noncertified centers (nCCs) within the IMPROVE study group. METHODS A validated survey assessing various factors, including stress urinary incontinence (SUI) and decision regret (DR), was administered to 950 patients who underwent RP across 19 hospitals (12 CCs and
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Centralizing Penile Cancer Care in Germany and Austria: Just a Dream or a Fast-Approaching Reality? Results of a Survey Study among Urological Department Chairs and Modeling of Real Treatment Numbers of Penile Cancer Patients. Urol. Int. (IF 1.6) Pub Date : 2023-11-02 Abdulbaki Yakac,Steffen Lebentrau,Lukas Lusuardi,Semih Sarcan,Maximilian Burger,Axel S Merseburger,Jens Wiegland,Christian Gilfrich,Ingmar Wolff,Sascha Ahyai,Matthias May,Christian Thomas
INTRODUCTION In countries characterized by a centralization of therapy management, patients with penile cancer (PeCa) have shown improvements in guideline adherence and ultimately, improved carcinoma-specific survival. Germany and Austria (G + A) have no state-regulated centralization of PeCa management, and the perspectives of urological university department chairs (UUDCs) in these countries, who
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Mid-Perineal Scrotal Flap for the Repair of Urorectal Fistulas: A New Technique. Urol. Int. (IF 1.6) Pub Date : 2023-10-30 Luis Martinez-Piñeiro
Rectourethral fistula (RUF) is an infrequent but severe complication of the treatment of prostate cancer. Herein, we describe a new surgical approach used successfully in 3 patients that incorporates a partially de-epithelialized mid-perineal scrotal flap (MPSF), used as interposition flap, that can be used in almost every patient with RUF after radiotherapy, regardless of having or not a concomitant
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Smile Incision-Modified Technique for Better Scrotal Outcome in Surgical Management of Penile Paraffinoma. Urol. Int. (IF 1.6) Pub Date : 2023-10-30 Nanda Daniswara,Pramatama Andhika Sunarso Pandoyo,Eriawan Agung Nugroho,Ardy Santosa,Mohamad Adi Soedarso,Sofyan Rais Addin,Dimas Sindhu Wibisono,Fandy Wicaksono
INTRODUCTION Penile augmentation with foreign material injection is used to increase penile length, girth, or both. Most of these individuals develop complications due to an abnormal mass formation known as penile paraffinoma. Multiple surgical techniques for restoring penile function and correcting near-normal penile shape have been developed, but prior techniques have some post-operative complications
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Needle-Perc-Assisted Endoscopic Surgery in Treatment with Renal Staghorn Stones: A Prospective Randomized Controlled Study from a Large-Volume Stone Center. Urol. Int. (IF 1.6) Pub Date : 2023-10-26 Bo Xiao,Xiaolin Diao,Xue Zeng,Song Jin,Gang Zhang,Wenjie Bai,Jianxing Li
INTRODUCTION The goal of this study was to evaluate the efficacy and safety of needle-perc-assisted endoscopic surgery (NAES) in the treatment of staghorn renal stones via a single-center prospective randomized controlled study. METHODS A total of 219 patients with partial or complete staghorn renal stones were prospectively randomized into two groups between January 2020 and April 2022. In group A
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Solitary Fibrous Tumor of the Prostate Treated with Frozen-Section Supported Robot-Assisted Nerve-Sparing Radical Prostatectomy. Urol. Int. (IF 1.6) Pub Date : 2023-10-25 Lara Franziska Stolzenbach,Christian D Fankhauser,Agostino Mattei,Christoph Würnschimmel
INTRODUCTION Solitary fibrous tumors (SFTs) of the prostate are extremely rare. We report on a 60-year-old man who was diagnosed with prostatic SFT through transurethral resection (TUR) of the prostate, and we provide a narrative literature review to put the case into perspective. We looked into multiple databases for articles published before June 2022. CASE REPORT A 60-year-old man without comorbidities
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Double-Layered Hand-Sewn versus Stapled Intestinal Anastomosis in Patients Who Underwent Ileal Urinary Diversion in Radical Cystectomy: A Comparative and Cost Effective Study. Urol. Int. (IF 1.6) Pub Date : 2023-10-06 Gabriele Tulone,Nicola Pavan,Sofia Giannone,Alberto Abrate,Piero Mannone,Davide Baiamonte,Francesco Claps,Rosa Giaimo,Marta Rossanese,Vincenzo Ficarra,Alchiede Simonato
INTRODUCTION Intestinal anastomosis can be performed by hand suturing (single layer or double layer) or by a mechanical suturing machine. The aim of the study was to compare complications, operative time, and costs of the intestinal anastomosis techniques. METHODS A retrospective comparative study was conducted including patients who underwent radical cystectomy and uretero-ileo-cutaneostomy or vescica
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Urological Tumor: A Narrative Review of Tertiary Lymphatic Structures. Urol. Int. (IF 1.6) Pub Date : 2023-09-28 Chong Shen,Dong-Li Zhang,Xiao-Long Cheng,Wei-Chuan Zhang,Jian-Jun Zhao
BACKGROUND Tertiary lymphoid structures (TLSs), as ectopic lymphoid-like tissues, are highly similar to secondary lymphoid organs and are not only involved in chronic inflammation and autoimmune responses but are also closely associated with tumor immunotherapy and prognosis. The complex composition of the urological tumor microenvironment not only varies greatly in response to immunotherapy, but the
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Successful Kidney-Sparing Systemic Therapy for a High-Risk Ureteral Carcinoma Case. Urol. Int. (IF 1.6) Pub Date : 2023-09-25 Pu Yuan,Xinwei Li,Yujie Yuan,Peiyuan Xu,Hui Wang
Upper tract urothelial carcinoma (UTUC) refers to the malignancies located from renal calices toward the end of the ureter and could be classified as renal pelvis carcinoma and ureteral carcinoma. For high-risk UTUC cases with a normal contralateral kidney, radical nephroureterectomy is the standard treatment. As for low-risk UTUC cases or solitary kidney cases, kidney-sparing therapy may be a better
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The Role of Specificity Protein 1 (SP1) in Bladder Cancer Progression through PTEN-Mediated AKT/mTOR Pathway. Urol. Int. (IF 1.6) Pub Date : 2023-09-04 Zhiqiang Chen
INTRODUCTION The aim of the study was to investigate the potential mechanism of specificity protein 1 (SP1) in bladder cancer progression through the PTEN-mediated AKT/mTOR pathway. METHODS Human bladder cancer cell lines (HT-1197, HT-1376, and T24) and normal ureteral epithelial cell line SV-HUC-1 were used. SP1 expression was detected via quantitative real-time PCR and Western blotting. Cell viability
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Prognostic Ability of Nutritional Indices for Outcomes of Bladder Cancer: A Systematic Review and Meta-Analysis. Urol. Int. (IF 1.6) Pub Date : 2023-08-29 Huijie Jiao,Lin Wang,Xiaomei Zhou,Jiacheng Wu,Tiantian Li
BACKGROUND Nutrition has become an important parameter influencing the prognosis of several cancers. However, its impact on outcomes for bladder cancer (BC) is still unclear. This review examines the association between three commonly used nutritional indices, namely, the prognostic nutritional index (PNI), controlling nutritional status (CONUT), and the geriatric nutritional risk index (GNRI) and
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Retrograde Intrarenal Surgery Learning Curves of Urology Residents Supervised by an Experienced Endourologist: An RIRSearch Study. Urol. Int. (IF 1.6) Pub Date : 2023-08-24 Mehmet Fatih Şahin,Oktay Ozman,Hakan Cakir,Onder Cinar,Murat Akgul,Cem Basatac,Muhammed Fatih Simsekoglu,Kerem Teke,Cenk Murat Yazici,Eyup Burak Sancak,Bülent Önal,Haluk Akpinar
INTRODUCTION Although retrograde intrarenal surgery (RIRS) is being performed with increasing frequency, there are only a limited number of studies about the learning curve (LC). This study aimed to analyze the LC of RIRS for five surgeons who underwent the same training. MATERIALS AND METHODS The data of the 410 patients who underwent RIRS between April 2017 and 2022 in a single institution, which
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Efficacy and Safety of Extracorporeal Shock Wave Therapy in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Acquired Premature Ejaculation Patients. Urol. Int. (IF 1.6) Pub Date : 2023-08-23 Dogukan Sokmen,Yusuf Ilker Comez
INTRODUCTION The aim of this study was to evaluate the efficacy and safety of extracorporeal shock wave therapy (ESWT) in patients with acquired premature ejaculation (APE) due to chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). METHOD Patients with APE due to CP/CPPS between January 2020 and June 2022 were included in the study. Demographic data of the patients were recorded, and the degree
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Urinary Incontinence, Quality of Life, and Risk Factors in a Geriatric Cohort. Urol. Int. (IF 1.6) Pub Date : 2023-08-23 Klaus Eredics,Clemens Wehrberger,Leo Edlinger,Ulrik Müller,Michael Rauchenwald,Marlies Wehrberger,Stephan Madersbacher
INTRODUCTION The aim of the study was to evaluate the prevalence of urinary incontinence (UI) and its subtypes, associated clinical factors, and impact on quality of life (QoL) in a geriatric population aged 80 years or older. METHODS Male and female residents (inclusion criterion: 80 years or older) of three Viennese senior citizen homes were personally interviewed with the aid of a structured questionnaire
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A Retrospective Analysis of 83 Patients with Testicular Mass Who Underwent Testis-Sparing Surgery: The Eurasian Uro-oncology Association Multicenter Study. Urol. Int. (IF 1.6) Pub Date : 2023-08-17 Murat Keske,Abdullah Erdem Canda,Mert Ali Karadag,Halil Çiftçi,Sakip Erturhan,Cagri Kactan,Mustafa Soytas,Fatih Özkaya,Isa Ozbey,Eser Ordek,Ali Fuat Atmaca,Asif Yildirim,Selcuk Sahin,Yunus Colakoglu,Ugur Boylu,Bulent Erol,Turhan Caskurlu,Murat Can Kiremit,Ozer Ural Cakici,Gokhan Sonmez,Hakan Kılıçarslan,Ziya Akbulut,Onur Kaygısız,Selahattin Bedir,Hakan Vuruskan,Yunus Erol Bozkurt,Hasan Riza Aydin,Ural
INTRODUCTION Herein, we analyzed the histopathological, oncological and functional outcomes of testis-sparing surgery (TSS) in patients with distinct risk for testicular cancer. METHODS This is a multicenter retrospective study on consecutive patients who underwent TSS. Patients were categorized in high- or low-risk testicular germ cell tumor (TGCT) according to the presence/absence of features compatible
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Phytotherapy (BNO 1045) of Acute Lower Uncomplicated Urinary Tract Infection in Women Normalizes Local Host Responses. Urol. Int. (IF 1.6) Pub Date : 2023-08-04 Daniel S C Butler,Florian Wagenlehner,Martina Höller,Dimitri Abramov-Sommariva,Hubert Steindl,Kurt G Naber
INTRODUCTION Acute lower uncomplicated urinary tract infection (uUTI) affects a large proportion of women. Increased antimicrobial resistance has created an urgent need for novel therapeutics and the phytotherapeutic drug BNO 1045 (Canephron® N) has previously been shown to be noninferior to standard antimicrobial stewardship. This sub-analysis from a randomized, double-blind, controlled phase III
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Rare Case of Managing and Evaluating Viability after Replantation of a Serial Self-Amputated Bilateral Testis by a Patient with Schizophrenia: A Case Report. Urol. Int. (IF 1.6) Pub Date : 2023-08-04 Il Young Ahn,Moon Soo Ha,Woo Ju Kim,Tae Hui Bae,Sun Mi Kim,Se Young Choi,Shin Hyuk Kang
Amputation of the testis is very rare in clinical situations; therefore, most surgeons have no experience with an amputated testis. In this case, a 31-year-old male with schizophrenia amputated both testes due to self-mutilation. We performed replantation surgery via microscopy. On postoperative day 1, he removed his right testis by using his hand, even though his hands were restrained. The second
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Transobturator Tension-Free Vaginal Flap Operation versus Synthetic Transobturator Tape for Treatment of Female Stress Urinary Incontinence: A Prospective Randomized Study. Urol. Int. (IF 1.6) Pub Date : 2023-07-27 Wally Mahfouz,Ahmed Abulfotooh Eid,Mohamed Elbadry,Abdelrahman Elkhiat,Ahmed Moussa,Akram Assem
INTRODUCTION Synthetic mid-urethral slings (MUSs) are the gold standard treatment for female stress urinary incontinence (SUI). Recently, there have been reports of serious adverse events with synthetic tapes such as urethral erosion, vaginal erosion, and mesh infection. Tension-free vaginal flap (TVF) operation has been proven to be successful as a natural alternative to synthetic slings. We propose
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The Role of Urine and Washing Cytology in Primary Transurethral Resection of Bladder Tumours. Urol. Int. (IF 1.6) Pub Date : 2023-07-27 Julian P Struck,Tomasz Ozimek,Maike Schnoor,Anne Offermann,Marlis Guenther,Marie C Roesch,Judith R Wießmeye,Alexander Katalinic,Sven Perner,Hendrik Borgmann,Axel S Merseburger,Mario W Kramer
INTRODUCTION Urine cytology (UC) is a recommended tool for the diagnosis of urothelial malignancies. Thus far, no specific recommendations regarding the role of washing cytology (WC) have been included in the guidelines. The goal of our study was to analyse the relationship between the histology of transurethrally (transurethral resection of the bladder [TURBT]) resected bladder tumours (BCa) and intraoperative
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The Surgical Management of Large Bladder Calculi and Irreducible Uterine Prolapse: A Case Report and Review of Literature. Urol. Int. (IF 1.6) Pub Date : 2023-07-24 Wanchat Komon,Apisith Saraluck,Wit Viseshsindh,Orawee Chinthakanan
Bladder calculi are rare in women. We report a case of bladder calculi complicating irreducible uterovaginal prolapse. It provides diagnostic and operative challenges to the management team. A 77-year-old woman presented with irreducible complete uterovaginal prolapse. Bladder stones were appreciated on examination and confirmed with imaging. The patient was managed surgically with transabdominal hysterectomy
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Tyrosine Kinase Inhibitors for Renal Cell Carcinoma: A Bibliometric Analysis via CiteSpace from 2000 to 2022. Urol. Int. (IF 1.6) Pub Date : 2023-07-14 Jinbin Xu,ZhanSen Huang,ShunTian Gao,GengGuo Deng,Jinming Di
BACKGROUND The aim of the study was to identify the cooperation of authors, countries, institutions and explore the hot spots regarding research of tyrosine kinase inhibitors (TKIs) for renal cell carcinoma (RCC) treatment in the past 22 years. SUMMARY Relevant original and review articles were obtained from the Web of Science Core Collection from 2000 to 2022. CiteSpace software was used to perform
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Optimal Dwelling Time for Ureteral Stents Placed for Passive Dilation after Impassable Ureteroscopy. Urol. Int. (IF 1.6) Pub Date : 2023-07-14 Ali Kaan Yildiz,Arif Bayraktar,Turgay Kacan,Buğra Bilge Keseroğlu,Berat Cem Ozgur,Omer Gokhan Doluoglu,Tolga Karakan
INTRODUCTION The aim of the study was to determine the correlation between the dwelling time for a ureteral stent placed for passive dilation after impassable ureteroscopy and success and complications. METHODS A retrospective evaluation was made of patients who underwent stent placement after impassable ureteroscopy and a repeat ureteroscopy due to kidney stones. A total of 161 patients were included
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Complete Blood Count Markers and C-Reactive Protein as Predictors of Testicular Viability in the Event of Testicular Torsion in Adults. Urol. Int. (IF 1.6) Pub Date : 2023-07-07 Eyal Barkai,Snir Dekalo,Ofer Yossepowitch,Jacob Ben-Chaim,Yuval Bar-Yosef,Avi Beri,Roy Mano
INTRODUCTION The association between blood markers and testicular viability after testicular torsion (TT) is not well known. We evaluated the role of complete blood count markers and C-reactive protein (CRP) in predicting testicular viability after TT. METHODS Fifty men, ≥18 years of age, operated for TT between the years 2015-2020 were enrolled. Blood markers including neutrophil-, lymphocyte-, and
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Succinate Dehydrogenase Defects Giant Renal Cell Carcinoma. Urol. Int. (IF 1.6) Pub Date : 2023-06-30 Xia Sun,Guang Wang,Ziye Huang,Pei Li,Bowei Yang,Tianyun Wang,Jiongming Li
Succinate dehydrogenase (SDH)-deficient renal cell carcinoma (RCC) is a new subtype of RCC included in the 2016 edition of the WHO classification in RCC. SDH-defective RCC accounts for 0.05-0.2%, and preoperative diagnosis is difficult. We report a severe adherent RCC of inferior vena cava that underwent open radical nephrectomy after preoperative renal artery embolization. Postoperative histopathological
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Preoperative Magnetic Resonance Imaging Cannot Predict the Presence of a Rare Myoid Gonadal Stromal Testicular Tumor: A Case Report. Urol. Int. (IF 1.6) Pub Date : 2023-06-30 Serdar Madendere,Mert Kılıç,Hakan Yıldırım,Süheyla Ekemen,Demir Kürşat Yıldız,Mevlana Derya Balbay
Testicular myoid gonadal stromal tumors (MGSTs) are rare neoplasms. While past research has detailed the pathological characteristics of these tumors, the radiological differences between MGST and other types of testicular tumors have not been elucidated. Our study aimed to reveal the possible distinctive features of MGST using magnetic resonance imaging (MRI). We report a 24-year-old patient presenting
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Evaluation of Gas 6 as a Prognostic Marker in Papillary Renal Cell Carcinoma. Urol. Int. (IF 1.6) Pub Date : 2023-06-22 Marie Mikuteit,Stefanie Zschäbitz,Christine Stöhr,Edwin Herrmann,Iris Polifka,Abbas Agaimy,Lutz Trojan,Philipp Ströbel,Frank Becker,Christian Wülfing,Peter Barth,Michael Stöckle,Michael Staehler,Christian Stief,Axel Haferkamp,Markus Hohenfellner,Stefan Duensing,Stephan Macher-Göppinger,Bernd Wullich,Joachim Noldus,Walburgis Brenner,Frederik Roos,Bernhard Walter,Wolfgang Otto,Maximilian Burger,Maximillian
INTRODUCTION Growth arrest-specific protein 6 (Gas 6) is a ligand that plays a role in proliferation and migration of cells. For several tumor entities, high levels of Gas 6 are associated with poorer survival. We examined the prognostic role of Gas 6 in renal cell carcinoma (RCC), especially in papillary RCC (pRCC), which is still unclear. METHODS The patients' sample collection is a joint collaboration
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Cruciferous Vegetable Intake and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis. Urol. Int. (IF 1.6) Pub Date : 2023-06-21 Jiaye Long,Zhaohui Liu,Shuai Liang,Baoxiang Chen
INTRODUCTION The relationship between cruciferous vegetables and prostate cancer (PCa) risk remains contentious. This study aimed to assess the association between consuming cruciferous vegetables and PCa risk. METHODS We carried out a systematic search through PubMed, Embase, Web of Science, and the Cochrane Library until September 20, 2022. The results of the article will be analyzed using the Stata
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Value of Prostate-Specific Antigen Kinetics in Patients with Low-Risk Prostate Cancer under Active Surveillance. Urol. Int. (IF 1.6) Pub Date : 2023-06-16 Pedro Jesús Fernández-Anguita,Marta Ventosa-Puig,Inmaculada Díaz de Mera-Sánchez Migallón,Oscar Legido-Gómez,Pedro Carrión-López,Jesus Martínez-Ruiz,Antonio Santiago Salinas-Sánchez,José Miguel Giménez-Bachs
INTRODUCTION This study analyzes the value of PSA kinetics, PSA speed (vPSA), and PSA doubling time (PSAdt), in patients with low-risk prostate cancer who are in an active surveillance (AS) program. METHODS An observational, retrospective, and longitudinal study of a sample of 86 patients included in AS program between January 2014 and October 2021 was conducted. A review of their medical records was
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A Giant Urachal Accessory Spleen: Case Report. Urol. Int. (IF 1.6) Pub Date : 2023-06-15 Wenmin Ma,Xuejin Ma,Lin Jiang,Wei Yang,Jiaren Zhang,Fangfang Mu,Shiguang Li
Accessory spleen (AS) refers to single or multiple splenic tissues which appear outside the relative normal spleen position results from embryonic dysplasia similar in structure and function to the spleen. AS is frequently observed in the splenic hilus and or adjacent to the tail of pancreas, and only a few cases occurred in the pelvic cavity. We present an extremely rare AS case in urachus, which
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Perioperative Outcome of Thulium Laser Enucleation of the Prostate versus Robot-Assisted Simple Prostatectomy: A Propensity Score-Matched Analysis. Urol. Int. (IF 1.6) Pub Date : 2023-06-12 Friedrich Otto Hartung,Karl-Friedrich Kowalewski,Fehmi Morina,Luisa Egen,Manuel Neuberger,Britta Gruene,Maren Wenk,Maximilian Christian Kriegmair,Philipp Nuhn,Paul Patroi,Niklas Westhoff,Patrick Honeck,Marie-Claire Rassweiler-Seyfried,Maurice Stephan Michel,Jonas Herrmann
INTRODUCTION The aim of this study was to investigate and compare clinical safety and efficiency of Thulium laser enucleation of the prostate (ThuLEP) and robot-assisted simple prostatectomy (RASP) for the treatment of large gland benign prostatic hyperplasia in a tertiary care center. METHODS Perioperative data of 39 patients who underwent RASP in our institution from 2015 to 2021 was collected. Propensity
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The Influence of Preoperative Hydronephrosis on the Prognosis after Radical Cystectomy among Patients with Different Pathological Stages of Bladder Cancer. Urol. Int. (IF 1.6) Pub Date : 2023-06-02 Jingwei Du,Hui Zhan,Jian Chen,Jiansong Wang,Shi Fu,Mingxia Ding,Ting Luan,Hairong Wei,Chengcai Yang
INTRODUCTION Preoperative hydronephrosis is closely associated with the prognosis of patients with bladder cancer. This study assesses the effect of preoperative hydronephrosis on the prognosis after radical cystectomy (RC) among patients with different pathological stages of bladder urothelial carcinoma. METHODS We retrospectively analyzed the clinical data of 231 patients who underwent RC because
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Adjustable Continence Therapy Balloons in Female Patients with Stress Urinary Incontinence: A Systematic Review. Urol. Int. (IF 1.6) Pub Date : 2023-06-02 Sonia Guérin,Zine-Eddine Khene,Benoit Peyronnet
INTRODUCTION The aim of this study was to perform a systematic review of studies reporting the outcomes of ACT® balloons in female patients with stress urinary incontinence (SUI) due to intrinsic sphincter deficiency (ISD). METHODS In accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) standards, a systematic search of the PubMed (Medline) and Scopus electronic
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The Change of Erectile Function Post Recovery from COVID-19 Infection. Urol. Int. (IF 1.6) Pub Date : 2023-05-30 Ali Ibrahim,Diaa-Eldin Taha,Ahmed Zeid,Khaled Magdy Zeinelabden,Tarek Abdelbaky,Hossam Nabeeh
INTRODUCTION We assess the correlation between COVID-19 infection and erection and evaluate the effect of aging and comorbidities on the male sexuality of patients with COVID-19 infection. METHODS 100 patients were enrolled and diagnosed with COVID-19 based on reverse transcription-polymerase chain reaction tests of oropharyngeal and nasopharyngeal swabs according to the WHO guidelines. The International
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Extrauterine Retroperitoneal Leiomyomas: 3 Case Reports and Review of the Literature. Urol. Int. (IF 1.6) Pub Date : 2023-05-30 Silvia Juste Álvarez,Natalia Rocío Miranda Utrera,José Manuel Duarte Ojeda,Raquel Sopeña Sutil,Javier Gil Moradillo,Félix Guerrero-Ramos,Mario Hernández-Arroyo,Rocío Santos Pérez De La Blanca,Alfredo Rodríguez Antolín,Carmen Gomez Del Cañizo
Leiomyomas are benign mesenchymal tumors which originate from smooth muscle cells. Extrauterine leiomyomas are rare and they may arise where smooth muscle cells are found. Their diagnosis is challenging due to their heterogeneous ways of presentation. Histological analysis may reveal areas of sarcomatous differentiation; therefore, complete resection of the entire tumor is the only curative treatment
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Revisiting Treatment Protocols for Stage I Testicular Seminoma: A SEER-Based Analysis. Urol. Int. (IF 1.6) Pub Date : 2023-05-15 Anas Elgenidy,Yousef Tarek Sonbol,Ahmed O Elmehrath,Ahmed M Afifi,Nirmish Singla
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Letter to the Editor regarding the Article "Postoperative Mortality Rate after Radical Cystectomy: A Systematic Review of Epidemiologic Series". Urol. Int. (IF 1.6) Pub Date : 2023-05-15 Pero Bokarica,Maša Alfirević,Adelina Hrkać,Ana Magdalena Glas,Igor Tomašković
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The Effect of Transversus Abdominis Plane Block in Kidney Transplantation: A Systematic Review and Meta-Analysis. Urol. Int. (IF 1.6) Pub Date : 2023-05-05 Changjian Zheng,Hongmei Yang,Lin Yang,Jun Luo,Bo Xiong
INTRODUCTION The aim of the study was to evaluate the effect of transversus abdominal (TAP) block for postoperative analgesia after renal transplantation. METHODS We searched PubMed, Embase, the Cochrane Library, and the Chinese Biomedical Literature Database for relevant studies. The related trials that met the inclusion criteria were analysed using RevMan 5.4 software. RESULTS We found 15 randomized
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Effects of Exercise on Physical Function and Quality of Life in Prostate Cancer Patients Receiving Androgen Deprivation Therapy: High-Intensity Interval Training versus Moderate-Intensity Continuous Training Urol. Int. (IF 1.6) Pub Date : 2023-04-25 Sangjun Yoo, Kyung Hee Lee, Parivash Jamrasi, Min Chul Cho, Wook Song, Hyeon Jeong
Introduction: We assessed the effects of exercise on the physical function and health quality of life (hQoL) in prostate cancer patients underwent androgen deprivation therapy (ADT). Additionally, the effects of high-intensity interval training (HIIT) on the physical function and hQoL in these patients were compared with those of moderate-intensity continuous training (MICT). Methods: Seventeen prostate
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Antibiotics in the Treatment of Uncomplicated Cystitis: A Google Trends Analysis Urol. Int. (IF 1.6) Pub Date : 2023-04-20 Müslim Doğan Değer, Serdar Madendere, Çetin Volkan Öztekin
Introduction: Using Google Trends (GT) data, the trend variations for the most common antibiotics used to treat uncomplicated cystitis were analyzed by time and region since 2004. Methods: GT was used to create a “line-graph” that shows how interest in a topic in certain locations has grown or decreased over time. The relative search volume, which is displayed on a scale of 0–100, was used to index
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Stone Occlusion Device with Drainage Function Is Effective in Ureteral Calculi Treatment: A Preliminary Report Urol. Int. (IF 1.6) Pub Date : 2023-04-19 Xiaochun Yi, Xin Li, Keliang Peng, Yueming Wan, Wangchun Liao, Sheng Li
Introduction: The aim of the study was to assess the efficacy and safety of ureterolithotripsy (URS) in treating ureteral calculi with holmium-YAG laser through adding retropulsion prevention and drainage function to ureteral catheter. Methods: An inner wire was fixed at the top of an Fr5 ureteral catheter and run through a tee joint. The proximal catheter was split into 4 strips. When the wire was
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Adrenal Tuberculosis: A Case Report and Literature Review Urol. Int. (IF 1.6) Pub Date : 2023-04-19 Hao Huang, Liang Gao, YaDong Li, Wei Tan, Hao Wu, Ye Yuan, Chuan Liu
Adrenal tuberculosis (TB) is a rare disease, which is difficult to diagnose because of its atypical symptoms. We reported a 41-year-old female who was admitted to hospital due to a left adrenal tumor, which was found in health examination without any symptoms. Abdominal CT showed a mass in her left adrenal. The results of blood test were normal. A retroperitoneal laparoscopic adrenalectomy was carried
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MR-Guided Transurethral Ultrasound Ablation of Prostate Cancer: Initial Experience of Monitoring Tumor Response by Dynamic Apparent Diffusion Coefficient Measurements at 3.0 T Urol. Int. (IF 1.6) Pub Date : 2023-04-18 Lena Meyer, Andreas Bohlscheid, Oscar Lemmer, Jeroen van de Plas, Francois Leboutte, Boris A. Hadaschik, Andreas Neisius, Winfried A. Willinek
Introduction: Diffusion-weighted imaging (DWI) as part of multiparametric magnetic resonance imaging (mpMRI) is an important sequence for the detection of prostate cancer (PCa). The objective of this retrospective analysis was to evaluate changes in apparent diffusion coefficient (ADC) measurements in biopsy-proven PCa undergoing TULSA-PRO (MR-guided transurethral ultrasound ablation of the prostate)
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Prospective Analysis of Versatility and User Satisfaction with a Novel Single-Use Cystoscope with Working Channel Urol. Int. (IF 1.6) Pub Date : 2023-04-18 Thomas Lütfrenk, Andreas Neisius, Steffen Rausch, Johannes Salem, Timur H. Kuru
Introduction: In the present study, a prospective systematic assessment of the clinical utility of the Ambu® aScopeTM 4 Cysto Reverse Deflection with regard to image quality, maneuverability, and navigation in an outpatient and inpatient setting was performed. Materials and Methods: A prospective multicenter study was performed for evaluation of the instrument during routine cystoscopy. We evaluated
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Avoiding Prostate Biopsies in Patients at Low Risk for Prostate Cancer: A Prospective Evaluation of a PSA-Density-Based Safety Net Urol. Int. (IF 1.6) Pub Date : 2023-04-14 Henning Bahlburg, Karl Tully, Vincent Hoffmann, Julian Hanske, Nicolas von Landenberg, Florian Roghmann, Rein-Jüri Palisaar, Joachim Noldus , Sebastian Berg, Marko Brock
Introduction and Objectives: Decision-making to perform prostate biopsy should include individual risk assessment. Patients classified as low risk by the Rotterdam Prostate Cancer Risk Calculator are advised to forego biopsy (PBx). There is concern about missing clinically significant prostate cancer (csPCa). A clear pathway for follow-up is needed. Material and Methods: Data for 111 consecutive patients
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LINC01002 Targets miR-650/FLNA Pathway to Suppress Prostate Cancer Progression Urol. Int. (IF 1.6) Pub Date : 2023-04-11 Li Qian, Yue Wang, Yuzhen Xiong, Hetian Ren, Shili Liu, Dandan Chen, Yang Liu
Introduction: In view of the vital implication of long noncoding RNAs in tumorigenesis, we possess the aim to determine the action effects and mechanisms of LINC01002 in prostate cancer (PCa). Methods: Expression level of LINC01002, miR-650, or filamin A (FLNA) in PCa tissues and cells was assessed using quantitative real-time PCR or Western blotting. Cell proliferative and migratory capacities were
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Unilateral Suprainguinal Ectopic Scrotum: Case Report and Literature Review Urol. Int. (IF 1.6) Pub Date : 2023-04-04 Hengyou Wang, Daxing Tang, Xiang Yan
Ectopic scrotum is an infrequent congenital scrotal anomaly. Different surgical methods of correcting ectopic scrotum have been used, but none have produced optimal cosmetic results for all types. We describe a case of left ectopic suprainguinal scrotum in a 14-month-old boy who had an undescended left testicle and a left-sided scrotal skin tag. Single-stage rotational flap scrotoplasty and unilateral
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Giant Hydronephrosis: A Rare Case Report and Literature Review Urol. Int. (IF 1.6) Pub Date : 2023-03-30 Nathan Wirtzfeld, Frédéric Leduc, Roland Vaesen
Giant hydronephrosis (GH), characterized by the presence of more than 1 L of fluid in the renal collecting system, is a rare urological condition, particularly in adults. Obstruction of the pyeloureteral junction is the most common cause of GH. We report the case of a 51-year-old man who presented with dyspnea, edema of the lower limbs, and major abdominal distension. The patient was diagnosed with