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Transjugular approach in aspiration thrombectomy and angioplasty of a thrombosed straight arteriovenous graft compared to the direct hemodialysis access approach Hemodial. Int. (IF 1.3) Pub Date : 2024-03-14 JungWon Kwak, Sung Bum Cho, Heungman Jun, Hwan Hoon Chung, Sung‐Joon Park, Tae‐Seok Seo, Woo Jin Yang
PurposeTo evaluate the efficacy and outcome of the transjugular approach in endovascular recanalization of a thrombosed straight arteriovenous graft (AVG) compared to those of the direct hemodialysis access approach (conventional approach).Materials and MethodsWe retrospectively assessed patients who underwent aspiration thrombectomy and percutaneous transluminal angioplasty for thrombosed straight
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Treatment of severe hyponatremia with continuous renal replacement therapy: A case and review of corrective strategies Hemodial. Int. (IF 1.3) Pub Date : 2024-03-12 Paul J. Der Mesropian, Shawn Phillips, Martha Naber, Sunjeev Konduru, Gulvahid Shaikh, Krishnakumar Hongalgi
Treatment of severely hyponatremic patients with continuous renal replacement therapy (CRRT) presents a unique challenge given the lack of commercial options for hypotonic replacement solutions or dialysate. We report the case of a 55‐year‐old male who presented with profound, symptomatic hyponatremia in the setting of acute kidney injury (AKI). The patient was found to have a serum sodium concentration
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Health‐related quality of life for pediatric patients with end‐stage kidney disease: A systematic review and meta‐analysis of the Pediatric Quality of Life Inventory (PedsQL) Hemodial. Int. (IF 1.3) Pub Date : 2024-03-12 Kush Doshi, Rupesh Raina, Kar Hui Ng, Vera Koch, Girish C. Bhatt, Arwa Nada, Brian Foresi, Sibee Sambandam Kamalakkannan, Mignon McCulloch, Sidharth Sethi, Maria Díaz‐González de Ferris
IntroductionHealth‐related quality of life (HRQoL) studies demonstrate the impact of end‐stage renal disease (ESRD) on the physical and psychosocial development of children. While several instruments are used to measure HRQoL, few have standardized domains specific to pediatric ESRD. This review examines current evidence on self and proxy‐reported HRQoL among pediatric patients with ESRD, based on
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The risk factors for arteriovenous fistula dysfunction in maintenance hemodialysis patients: A cross‐sectional study Hemodial. Int. (IF 1.3) Pub Date : 2024-03-07 Fan Zhang, Jie Yu, Guoli Li, Shuangshuang Fu, Hailang Xiao, Yiya Yang, Yumei Liang, Yinyin Chen, Xun Luo
IntroductionArteriovenous fistula (AVF) dysfunction is a prevalent complication among maintenance hemodialysis patients. However, the factors influencing AVF patency remain unclear. To address this, we conducted a study aimed at identifying factors contributing to AVF dysfunction in this patient population.MethodsThe study compared clinical data, vascular calcification score, and laboratory data focusing
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Accelerated neuropathy among chronic kidney disease patients undergoing hemodialysis: Analysis of an institutional cluster Hemodial. Int. (IF 1.3) Pub Date : 2024-03-07 Subrahmanian Sathiavageesan, Subramani Murugan
BackgroundAccelerated neuropathy is a rare syndrome of rapidly worsening peripheral neuropathy, typically described in end‐stage kidney disease (ESKD) patients undergoing dialysis. In our center, we encountered a surge in the occurrence of accelerated neuropathy among ESKD patients undergoing hemodialysis, which prompted systematic research.MethodsIn this case–control study, we present the clinical
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Dosing lutetium Lu 177‐dotatate for a hemodialysis patient Hemodial. Int. (IF 1.3) Pub Date : 2024-03-06 Lindsay Taylor, Richard Meades, Ann‐Marie Quigley, Christos Toumpanakis, Catriona Goodlad, Andrew Davenport
Lu177‐dotatate (Lutathera™) is a radioactive drug approved for the treatment of adults with gastro‐entero‐pancreatic neuroendocrine tumors and is predominantly renally excreted. Currently all patients receive 7400 MBq (200 mCi), and there are no guidelines for treating hemodialysis patients. We measured radioactivity prior to and post administration of two cycles of Lu177‐dotatate in a hemodialysis
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The use of lung ultrasound in evaluation of extravascular lung water in hemodialysis patients: Systematic review and meta-analysis Hemodial. Int. (IF 1.3) Pub Date : 2024-02-27 Anas Elgenidy, Mostafa Atef Amin, Ahmed K. Awad, Abdullah Emad, Abdelrahman Nassar, Omar Alomari, Radwa Ibrahim, Faeq Husain-Syed, Mostafa G. Aly
Determining dry weight is crucial for optimizing hemodialysis, influencing efficacy, cardiovascular outcomes, and overall survival. Traditional clinical assessment methods for dry weight, relying on factors such as blood pressure and edema, frequently lack reliability. Lung ultrasound stands out as a promising tool for assessing volume status, given its non-invasiveness and reproducibility. This study
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In memoriam: Todd S. Ing, MD, FACP Hemodial. Int. (IF 1.3) Pub Date : 2024-02-29 John T. Daugirdas, Philip Kam‐Tao Li, Michela Wrong
This special article describes the achievements and impact of Dr. Todd Siu‐Toa Ing, MBBS, (1933–2023) on the field of nephrology as recounted by a colleague from Hong Kong, a U.S. nephrologist ex‐trainee, and the daughter of an important mentor. Dr. Ing was a founding member of the International Society for Hemodialysis. He made important discoveries regarding the diagnosis of renal tubular acidosis
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Early endovascular approaches for treating acute mesenteric arterial occlusive disease in hemodialysis patients Hemodial. Int. (IF 1.3) Pub Date : 2024-02-22 Siyuan Qu, Rui Wen, Mingming Yan, Jiao Qin, Jiali Li
BackgroundAmong hemodialysis patients, acute superior mesenteric artery (SMA) thrombosis a condition with a high mortality rate. Very few larger case series have been reported.MethodWe reviewed eight hemodialysis patients with diabetes mellitus and SMA thrombosis managed with endovascular therapy in our institution. Demographic, clinical, and radiological data were described. The patency of the SMA
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Acute upper limb ischemia caused by thrombus shedding during arteriovenous graft thrombolysis: A case report Hemodial. Int. (IF 1.3) Pub Date : 2024-02-22 Changli Sun, Ziming Wan, Qiquan Lai, Bo Tu, Bo Chen
Acute upper limb ischemia is a rare, potentially limb‐ or life‐threatening vascular emergency that may lead to limb dysfunction or amputation. We present a patient undergoing maintenance hemodialysis who was hospitalized for arteriovenous graft thrombus complicated by acute upper limb ischemia arising from thrombus shedding to the fingertip arteries during thrombolysis. We successfully restored fingertip
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AshSR. Success is just running out of mistakes: a lifelong quest to make hemodialysis simple, safe, and effective. Pittsburgh, PA: Dorrance Publishing; 2023, 94 pp. ISBN: 979‐8‐8852‐7146‐2; eISBN: 979‐8‐8852‐7873‐7. Hemodial. Int. (IF 1.3) Pub Date : 2024-02-19 Fokko P. Wieringa
CONFLICT OF INTEREST STATEMENT No conflicts of interest to report.
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Is hemodiafiltration superior to high‐flow hemodialysis in reducing all‐cause and cardiovascular mortality in kidney failure patients? A meta‐analysis of randomized controlled trials Hemodial. Int. (IF 1.3) Pub Date : 2024-02-19 Paulo Roberto Bignardi, Vinicius Daher Alvares Delfino
IntroductionHemodiafiltration (HDF) and high‐flux hemodialysis (hf‐HD) are different methods of kidney replacement therapy (KRT) used for the treatment of kidney failure patients. A debate has raged over the last decade about the survival benefit of patients with the use of HDF compared with hf‐HD, but with divergent results from randomized controlled trials. Therefore, this study aimed to perform
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Successful twin pregnancy in a woman undergoing alternate diurnal and nocturnal hemodialysis Hemodial. Int. (IF 1.3) Pub Date : 2024-02-14 Geoffroy Desbuissons, Liliane Ngango, Christophe Baudeau, Philippe Fournier
Although pregnancy has become more frequent in patients undergoing hemodialysis, it remains a relatively rare event and carries a high risk of complications for both the mother and the fetus. In parallel, multiple pregnancies are also associated with a high risk of complications for the mother and the fetus, even in healthy women. The presence of a twin pregnancy in a woman with chronic renal failure
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Effect of conventional hemodialysis on the apixaban plasma concentration Hemodial. Int. (IF 1.3) Pub Date : 2023-11-14 Tim Poel, Nikki de Rouw, Nathalie C. V. Péquériaux, Daan van de Kerkhof, Annemieke M.A. Vermeulen Windsant, Rob J. van Marum, Angele P. M. Kerckhoffs
Apixaban is a factor Xa inhibitor used in patients undergoing hemodialysis treatment. The objective of this study is to investigate the effect of hemodialysis on apixaban plasma concentrations.
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Chronic kidney disease and value-based care: Lessons from innovation, iteration, and ideation in primary care Hemodial. Int. (IF 1.3) Pub Date : 2023-11-07 Matthew E. Berman, Joshua E. Lowentritt
Value-based primary care has reduced health care costs, improved the quality of rendered care, and enhanced the patient experience. Value-based care emphasizes prevention, outreach, follow-up, patient engagement, and comprehensive, whole-person health. Primary care Accountable Care Organizations have leveraged technology-enabled workflows, practice transformation, and cutting-edge data and analytics
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Age-associated effects of intradialytic exercise on physical function and nutritional status in patients receiving ambulatory hemodialysis: A multicenter cohort study Hemodial. Int. (IF 1.3) Pub Date : 2023-11-07 Ren Takahashi, Hiroki Yabe, Hideaki Ishikawa, Takashi Hibino, Tomoya Yamaguchi, Sayumi Morishita, Kenichi Kono, Yoshifumi Moriyama, Tetsuya Yamada
Intradialytic exercise is essential for improving physical function for older patients. This study aimed to examine the relationship between the effects of exercise therapy and aging.
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A phase 3b, multicenter, open-label, single-arm study of roxadustat within a US dialysis organization: The DENALI study Hemodial. Int. (IF 1.3) Pub Date : 2023-10-24 John Larkin, Jeffrey Hymes, Marcus L. Britton, Yemmie Oluwatosin, Jacqueline Nolen, Lixia Zhu, Arnold Silva
Roxadustat is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor approved in several regions for the treatment of anemia of chronic kidney disease (CKD). DENALI, a phase 3b study, evaluated the efficacy, safety, and feasibility of roxadustat in patients with anemia of CKD receiving in-center or home dialysis.
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Myocardial markers are highly altered by higher rates of fluid removal during hemodialysis Hemodial. Int. (IF 1.3) Pub Date : 2023-10-24 Junko Goto, Michael Ott, Bernd Stegmayr
Although hemodialysis is lifesaving in patients with kidney failure extensive interdialytic weight gain (IDWG) between dialyses worsens the prognosis. We recently showed a strong correlation between IDWG and predialytic values of cardiac markers. The aim of the present study was to evaluate if the cardiac markers N-terminal pro-B-type natriuretic peptide (proBNP) and troponin T were influenced by IDWG
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Higher NT-proBNP levels and the risk of intradialytic hypotension at hemodialysis initiation Hemodial. Int. (IF 1.3) Pub Date : 2023-10-24 Katherine A. Curtis, Sushrut S. Waikar, Finnian R. Mc Causland
Elevated N-terminal pro B-type natriuretic peptide (NT-proBNP) is a potent predictor of adverse outcomes in hemodialysis initiation. These patients often experience intradialytic hypotension, which may partially reflect cardiac dysfunction, but the association of NT-proBNP with intradialytic hypotension is not clear.
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Dr. Andreas Pierratos, MD, FRCPC Hemodial. Int. (IF 1.3) Pub Date : 2023-10-24 Christopher T. Chan
CONFLICT OF INTEREST STATEMENT Dr. Chan holds the R. Fraser Elliot Chair in Nephrology and consulted for Medtronic, Quanta and Dialco Inc. Dr. Chan is the President of the International Society for Hemodialysis.
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Elevated intraneural vascularization of the median nerve proximal to the arteriovenous fistula in hemodialysis patients suspected of carpal tunnel syndrome: A case series Hemodial. Int. (IF 1.3) Pub Date : 2023-10-23 Carina N. Bagge, Kristine Lindhard, Ylian S. Liem, Janus Kaufmann Lindquist, Eszter Balazs-Becsi, Nils Wolfram
Patients with end-stage kidney disease may require creation of an arteriovenous fistula in order to receive hemodialysis treatment. The creation may result in several complications, including carpal tunnel syndrome. Early diagnosis and treatment are essential to relieve symptoms, prevent permanent nerve damage, and improve quality of life. However, the sensory and motor disturbances resembling carpal
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The role of calcitonin gene-related peptide and substance P in the pathogenesis of dialysis headache Hemodial. Int. (IF 1.3) Pub Date : 2023-10-18 Gizem Gürsoy, Serhat Karadağ, Şennur Köse, Tamer Şakacı, Sibel Yücel Koçak, Yasemin Erdoğan Döventaş, Ayla Çulha Oktar, Muhammet Duran Bayar
The present study aims to establish the role of serum CGRP and SP levels in the disease pathophysiology in patients with dialysis headache not accompanied by primary or secondary headaches, and also whether there is a correlation between these vasoactive peptides and the severity of headache.
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Effect of vitamin D supplementation on management of anemia in hemodialysis patients with vitamin D deficiency: A double-blind, randomized, controlled trial Hemodial. Int. (IF 1.3) Pub Date : 2023-10-18 Sameh Mohamed Emarah, Mohamed Abd El Rahman Ahmed, Ghada Mohamed El Kannishy, Ahmed Elsaeed Abdulgalil
Anemia and vitamin D deficiency are common problems among hemodialysis (HD) patients. This study aimed to assess the impact of correction of vitamin D deficiency with vitamin D supplementation on the improvement of anemia in patients with end-stage renal disease (ESRD) on maintenance HD.
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Intravascular volumes and the influence on anemia assessed by a carbon monoxide rebreathing method in patients undergoing maintenance hemodialysis Hemodial. Int. (IF 1.3) Pub Date : 2023-10-12 Vårin Vinje, Tobias Bomholt, Carsten Lundby, Peter Oturai, Marianne Rix, Kristine Lindhard, Mads Hornum
Fluid overload is a major challenge in hemodialysis patients and might cause hypervolemia. We speculated that hemodialysis patients reaching dry weight could have undetected hypervolemia and low hemoglobin (Hb) concentration (g/dL) due to hemodilution.
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The relationship between skeletal muscle mass and exercise capacity in patients undergoing hemodialysis: An exploratory secondary-analysis Hemodial. Int. (IF 1.3) Pub Date : 2023-10-10 Xuanrui Zhang, Yan Zhuang, Wen Qin, Lun Yang, Yan Song
Protein-energy wasting is commonly observed in patients undergoing hemodialysis, leading to reduced muscle mass and, in severe cases, sarcopenia, which significantly impacts the patients' quality of life and clinical outcomes. Exercise interventions are frequently employed to address muscle loss in these patients. However, the relationship between exercise capacity and skeletal muscle mass in this
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The effect of teach-back versus pictorial image educational methods on knowledge of renal dietary restrictions in elderly hemodialysis patients with low baseline health literacy Hemodial. Int. (IF 1.3) Pub Date : 2023-10-09 Mohammad Sadegh Mozafari, Fereshteh Besharati, Parand Pourghane, Bahareh Gholami-Chaboki
Adherence to renal dietary restrictions is an important method for minimizing complications in dialysis patients. This study aimed to investigate the effect of teach-back versus pictorial image educational methods on knowledge of renal dietary restrictions among elderly hemodialysis patients in Iran. Selected markers of diet and kidney function were also measured.
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Comparison of supraclavicular brachiocephalic and femoral vein approaches for tunneled dialysis catheter placement in patients with thrombosed internal jugular veins Hemodial. Int. (IF 1.3) Pub Date : 2023-10-05 Umut Oguslu, Burçak Gümüş, Murat Yalçin, Osman Zikrullah Sahin, Gökalp Yilmaz
There is still debate on the best access route in case of bilateral internal jugular vein thrombosis. We aimed to compare the safety, effectiveness, and outcomes of tunneled dialysis catheter placement via supraclavicular brachiocephalic and femoral vein approaches in patients with bilateral internal jugular vein thrombosis.
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Prosthesis use and the change in activities of daily living following below-knee amputation in patients undergoing hemodialysis Hemodial. Int. (IF 1.3) Pub Date : 2023-10-04 Hayato Yamazaki, Shota Matsufuji, Aina Nishikawa, Masahiro Ashida, Masao Yamaguchi, Motohiko Sato, Nobuhiro Tanimura, Yoshihiro Tsujimoto, Takanobu Ubai, Tetsuo Shoji
Patients undergoing hemodialysis are at an increased risk of peripheral arterial disease, amputation of lower extremities, and decline of activities of daily living. Although a prosthesis is used to support activities of daily living, no previous study reported the association of prosthesis use with the change in activities of daily living following leg amputation in hemodialysis patients. The purpose
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Metformin-associated lactic acidosis (MALA): Is it an underestimated entity? A retrospective, single-center case series Hemodial. Int. (IF 1.3) Pub Date : 2023-09-30 Susan Kim, Amara Sarwal, Xin Tan Yee, Sebastian A. Gandarillas Fraga, Vincent Campion, Isaiarasi Gnanasekaran
Metformin is widely considered a first-line antiglycemic agent due to its cost-effectiveness and favorable adverse effect profile. However, its use is prohibited in patients with an estimated glomerular filtration rate <30 mL/min/1.73 m2, due to the risk of potentially lethal metformin-associated lactic acidosis (MALA). We sought to evaluate MALA cases and outcomes at our institution.
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Longitudinal micro-incision creation prior to balloon angioplasty for treatment of arteriovenous access dysfunction in a real-world patient population: 6-month cohort analysis Hemodial. Int. (IF 1.3) Pub Date : 2023-08-17 John Aruny, Jeffrey E. Hull, Alexander Yevzlin, Alejandro C. Alvarez, Jason D. Beaver, Robert W. Heidepriem, Michael T. Serle
Routine hemodialysis depends on well-functioning vascular access. In the event of vascular access dysfunction, percutaneous transluminal balloon angioplasty (PTA) is conducted to restore patency. Although an angioplasty procedure can provide an excellent immediate result by opening the access to allow dialysis to continue, the long-term patency rates are less than satisfactory. The goal of this study
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Improved nursing home end-stage renal disease patient participation in physical therapy with onsite, more frequent dialysis Hemodial. Int. (IF 1.3) Pub Date : 2023-08-10 Eran Y. Bellin, William T. Markis, Alice M. Hellebrand, Christine M. Busby, Katy A. Wane, Camille R. Jordan, Jordan G. Ledvina, Steven M. Kaplan, Todd R. Metzroth, Greg S. Williams, Arif Nazir, Nathan W. Levin, Allen M. Kaufman
For end-stage renal disease (ESRD) patients residing in skilled nursing facilities (SNFs), the logistics and physical exhaustion of life-saving hemodialysis therapy often conflict with rehabilitation goals. Integration of dialysis care with rehabilitation programs in a scalable and cost-efficient manner has been a significant challenge. SNF-resident ESRD patients receiving onsite, more frequent hemodialysis
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Long-term patency of arteriovenous fistulas for hemodialysis: A decade's experience in a transplant unit Hemodial. Int. (IF 1.3) Pub Date : 2023-08-06 Matthias Pfister, Lorenzo Viggiani d'Avalos, Philip C. Müller, Olivier de Rougemont, Marco Bonani, Adrian Kobe, Gilbert Puippe, Felix Nickel, Fabian Rössler
The heterogeneous quality of studies on arteriovenous fistulas outcome, with variable clinical settings and large variations in definitions of patency and failure rates, leads to frequent misinterpretations and overestimation of arteriovenous fistula patency. Hence, this study aimed to provide realistic and clinically relevant long-term arteriovenous fistula outcomes.
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Glucose variability in maintenance hemodialysis patients with type 2 diabetes. Hemodial. Int. (IF 1.3) Pub Date : 2023-07-20 Lucia Fačkovcová,Drazenka Pongrac Barlovic,Jan Brož
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International Society for Hemodialysis—A new horizon Hemodial. Int. (IF 1.3) Pub Date : 2023-07-19 Christopher Chan
CONFLICT OF INTEREST STATEMENT Christopher Chan is the President of the International Society for Hemodialysis. Christopher Chan holds the R Fraser Elliott Chair in Home Dialysis and serves as consultant to Medtronic, Quanta, and Dialco Inc. He received an investigator-initiated grant from Medtronic ERP program.
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Effect of needle orientation during arteriovenous access puncture on needed compression time after hemodialysis: A randomized controlled trial Hemodial. Int. (IF 1.3) Pub Date : 2023-07-06 Valérie Loizeau, Hanan Tanouti, Audrie Marcheguet, Guillaume Loubière, Philippe Aegerter, Hocine Drioueche, Sandra Pembebjoglou
There are two techniques for puncturing an arteriovenous fistula: one where the needle is inserted bevel up and then rotated to a bevel down position, and another where the needle is inserted bevel down. The aim of this study was to compare these two methods of needle insertion on minimum compression time required for hemostasis after needle removal.
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Evaluation of partial pressure CO2 change in the dialyzer blood inlet during hemodialysis as a measure of vascular access recirculation Hemodial. Int. (IF 1.3) Pub Date : 2023-06-28 Silverio Rotondi, Adolfo Perrotta, Giovanni Pintus, Laura Capasso, Marzia Pasquali, Alessio Farcomeni, Emanuela Paoloni, Sandro Mazzaferro, Lida Tartaglione
Vascular access recirculation during hemodialysis is associated with reduced effectiveness and worse survival outcomes. To evaluate recirculation, an increase in pCO2 in the blood of the arterial line during hemodialysis (threshold of 4.5 mmHg) was proposed. The blood returning from the dialyzer in the venous line has significantly higher pCO2, so in the presence of recirculation, pCO2 in the arterial
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A phase 3b, multicenter, open-label, single-arm study of roxadustat (ASPEN): Operational learnings within United States dialysis organizations Hemodial. Int. (IF 1.3) Pub Date : 2023-06-28 Steven Fishbane, Mark Vishnepolsky, Yemmie Oluwatosin, Jacqueline Nolen, Lixia Zhu, Kerry Cooper, Amy Young
Roxadustat is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor approved in several regions for the treatment of anemia of chronic kidney disease (CKD). ASPEN evaluated the efficacy, safety, and feasibility of roxadustat in patients with anemia of CKD in US dialysis organizations.
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Necessity of adjusting the blood hemoglobin target owing to interdialytic weight gain in patients on maintenance hemodialysis. Hemodial. Int. (IF 1.3) Pub Date : 2023-06-26 Masayuki Tanemoto
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Pharmacotherapy considerations in pregnant patients on hemodialysis Hemodial. Int. (IF 1.3) Pub Date : 2023-06-21 Beatrice Drambarean, Justyna Mastalerz, Lisa Wendt, Stephanie Toth-Manikowski
Successful pregnancy rates on dialysis are increasing with the advent of intensive hemodialysis and advances in medical management.
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Effects of using a stress ball on anxiety and depression in patients undergoing hemodialysis: A prospective, balanced, single-blind, crossover study Hemodial. Int. (IF 1.3) Pub Date : 2023-06-15 Nurten Ozen, Soner Berse, Betul Tosun
Use of a stress ball is a known t non-pharmacological method to distract attention and to relieve stress and anxiety. The goal of our study was to evaluate the effect of stress ball use on anxiety and depression in hemodialysis patients.
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Discrepancy in responses to the surprise question between hemodialysis nurses and physicians, with focus on patient clinical characteristics: A comparative study Hemodial. Int. (IF 1.3) Pub Date : 2023-06-15 Jeanette M. Wallin, Stefan H. Jacobson, Lena Axelsson, Jenny Lindberg, Carina I. Persson, Jenny Stenberg, Agneta Wennman-Larsen
The surprise question (SQ) “Would I be surprised if this patient died within the next xx months” can be used by different professions to foresee the need of serious illness conversations in patients approaching end of life. However, little is known about the different perspectives of nurses and physicians in responses to the SQ and factors influencing their appraisals. The aim was to explore nurses'
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Comparing the Fried frailty phenotype versus the Veterans Affairs frailty index among dialysis dependent patients Hemodial. Int. (IF 1.3) Pub Date : 2023-06-15 Anum Hamiduzzaman, Ruoxue Wu, Victoria Murray, Kamyar Kalantar-Zadeh, Elani Streja, John Sy
Frailty in dialysis patients is a modifiable disease state which can increase mortality if left untreated but remains underdiagnosed as frailty evaluations can be arduous or time consuming. We evaluate the agreement between a clinical frailty construct (Fried frailty phenotype, FFP) against and an electronic health record-based Veterans Affairs Frailty Index (VAFI) and their association with mortality
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Remission of refractory Crohn's disease with anti-IL-12/23 therapy in a patient undergoing hemodialysis: A case report Hemodial. Int. (IF 1.3) Pub Date : 2023-06-14 Michail Spathakis, Eirini Filidou, George Kolios, Dimitrios Papazoglou, Stergios Vradelis
Crohn's disease is a relapsing chronic inflammatory condition of the intestine with increasing prevalence around the world. Biologic therapies are currently widely used and have proved safe and effective in treating moderate to severe Crohn's disease. However, contemporary bibliography contains little information about the use of these drugs in patients with end-stage renal disease undergoing hemodialysis
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Interactions between intradialytic central venous oxygen saturation, relative blood volume, and all-cause mortality in maintenance hemodialysis patients Hemodial. Int. (IF 1.3) Pub Date : 2023-06-12 Priscila Preciado, Laura Rosales Merlo, Hanjie Zhang, Jeroen P. Kooman, Frank M. van der Sande, Peter Kotanko
In maintenance hemodialysis (HD) patients, low central venous oxygen saturation (ScvO2) and small decline in relative blood volume (RBV) have been associated with adverse outcomes. Here we explore the joint association between ScvO2 and RBV change in relation to all-cause mortality.
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Effects of denosumab on bone mineral density and bone metabolism in patients with end-stage renal disease: A systematic review and meta-analysis Hemodial. Int. (IF 1.3) Pub Date : 2023-06-01 Zhaoyan Gu, Xuhui Yang, Yan Wang, Jianjun Gao
The effects of denosumab on bone mineral density (BMD) and metabolism in patients with end-stage renal disease (ESRD) remain controversial. Hence, we performed a systematic review and meta-analysis of observational studies.
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Obesity and survival in a national cohort of incident hemodialysis patients: An analysis of the Brazilian Dialysis Registry Hemodial. Int. (IF 1.3) Pub Date : 2023-06-01 Angélica Peçanha, Fabiana B. Nerbass, Ricardo C. Sesso, Jocemir R. Lugon
A phenomenon called the “obesity paradox” has consistently been reported in several cohorts of patients on chronic hemodialysis. In this setting, a higher body mass index (BMI) is paradoxically associated with better survival. This study aimed to evaluate the effect of BMI on mortality in patients undergoing chronic hemodialysis using the Brazilian Dialysis Registry.
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Stroke and its correlates among patients on maintenance hemodialysis in Cameroon Hemodial. Int. (IF 1.3) Pub Date : 2023-06-01 Denis Georges Teuwafeu, Marie Patrice Halle, Nadine Aurore Kenfack, Cyrille Duquesne Nkouonlack, Hermine Fouda, Clovis Nkoke, Yacouba Mapoure Njankouo
End-stage kidney disease is an independent risk factor for stroke; however, the relationship between hemodialysis and stroke in Sub-Saharan Africa has not been established.
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Long term reduction of cardiovascular risk factors associated with three hour daily dialysis: A prospective, cohort study Hemodial. Int. (IF 1.3) Pub Date : 2023-06-01 Steven G. Achinger, Juan Carlos Ayus
Daily hemodialysis (DHD) compared to conventional hemodialysis (CHD) leads to improvements in left ventricular hypertrophy and mineral metabolism at 1-year follow-up. However, there is no information from prospective studies on the long terms effects of DHD on these key cardiovascular risk factors.
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Physician knowledge, attitudes, and practices regarding physical activity restrictions in pediatric hemodialysis patients Hemodial. Int. (IF 1.3) Pub Date : 2023-05-21 Raja Dandamudi, Katherine Twombley, Joseph T. Flynn, Aadil Kakajiwala, Deepa H. Chand
Epidemiologic studies of physical activity among pediatric hemodialysis (HD) patients are lacking. A sedentary lifestyle in End-Stage Kidney Disease is associated with a higher cardiovascular mortality risk. In those patients receiving HD, time spent on dialysis and restrictions on physical activity due to access also contribute. No consensus exists regarding physical activity restrictions based on
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Associations of interdialytic weight gain in the long intervals with mortality and residual kidney function decline Hemodial. Int. (IF 1.3) Pub Date : 2023-05-19 Yoshikazu Miyasato, Ramy M. Hanna, Tsuyoshi Miyagi, Yoko Narasaki, Hiroshi Kimura, Jun Morinaga, Masashi Mukoyama, Kamyar Kalantar-Zadeh
Interdialytic weight gain (IDWG) is crucial in the association between long interdialytic intervals and mortality in hemodialysis patients. The impact of IDWG on changes in residual kidney function (RKF) has not been evaluated thoroughly. This study examined the associations of IDWG in the long intervals (IDWGL) with mortality and rapid RKF decline.
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Pathways to improve nephrologist comfort in managing patients on in-center or home self-care dialysis Hemodial. Int. (IF 1.3) Pub Date : 2023-05-08 Minghui Huang, Anita Vincent Johnson, Negiin Pourafshar, Rakesh Malhotra, Jason Yang, Monarch Shah, Rasheed Balogun, Tushar Chopra
In end-stage kidney disease (ESKD), patient engagement and empowerment are associated with improved survival and complications. However, patients lack education and confidence to participate in self-care. The development of in center self-care hemodialysis can enable motivated patients to allocate autonomy, increase satisfaction and engagement, reduce human resource intensiveness, and cultivate a curiosity
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Microbiologic outcomes of ceftazidime-avibactam dosing in patients with sepsis utilizing renal replacement therapies Hemodial. Int. (IF 1.3) Pub Date : 2023-05-05 Wasim S. El Nekidy, Mooza Al Ali, Emna Abidi, Islam M. Ghazi, Nizar Attallah, Rania El Lababidi, Mohamad Mooty, Muriel Ghosn, Jihad Mallat
The suggested dose of ceftazidime-avibactam (CEF/AVI) in patient with multidrug resistant organisms and utilizing renal replacement therapies (RRTs) is not validated in clinical studies. The objective of this study was to evaluate the microbiologic cure of bacteremia and pneumonia using the recommended CEF/AVI dosing in patients utilizing RRT.
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Long-term efficacy and risk factors of balloon-assisted maturation for radial-cephalic arteriovenous fistula with small-caliber veins Hemodial. Int. (IF 1.3) Pub Date : 2023-05-03 Tsung-Chi Kao, Hung-Chang Hsieh, Sheng-Yueh Yu, Ta-Wei Su, Po-Jen Ko
Balloon angioplasty maturation (BAM) is a salvage method for autologous arteriovenous fistula (AVF) maturation failure. AVF creation using small-diameter veins is considered to have poor outcomes. Therefore, this study aimed to explore the long-term patency of small-diameter veins (≤3 mm) using BAM.
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Association between vascular access type and depression in hemodialysis patients Hemodial. Int. (IF 1.3) Pub Date : 2023-04-27 Ahmet Rıfkı Çora, Ersin Çelik
Hemodialysis is the most common treatment used for end-stage kidney disease (ESKD) patients and an arteriovenous fistula (AV) fistula is the preferred vascular access. The goal of our study was to investigate potential associations between vascular access type and depression.
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Switching from continuous veno-venous hemodiafiltration to intermittent sustained low-efficiency daily hemodiafiltration (SLED-f) in pediatric acute kidney injury: A prospective cohort study Hemodial. Int. (IF 1.3) Pub Date : 2023-04-25 Sidharth Kumar Sethi, Rupesh Raina, Shyam Bihari Bansal, Anvitha Soundararajan, Maninder Dhaliwal, Veena Raghunathan, Meenal Kalra, Kritika Soni, Samit Kumar Mahato, Ananya Vadhera, Dinesh Kumar Yadav, Timothy Bunchman
Continuous kidney replacement therapy (CKRT) is the preferred modality in critically ill children with acute kidney injury. Upon improvement, intermittent hemodialysis is usually initiated as a step-down therapy, which can be associated with several adverse events. Hybrid therapies such as Sustained low-efficiency daily dialysis with pre-filter replacement (SLED-f) combines the slow sustained features
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Incidence of hospital admissions in bioimpedance-guided fluid management among maintenance hemodialysis patients—Results of a randomized controlled trial Hemodial. Int. (IF 1.3) Pub Date : 2023-04-17 Kaiane Stigger, Larissa Ribas Ribeiro, Fernanda Moraez Cordeiro, Maristela Böhlke
Hemodialysis is life-sustaining in kidney failure. However, proper regulation of body fluids depends on an accurate estimate of target weight. This trial aims to compare clinical endpoints between target weight estimation guided by bioimpedance spectroscopy and usual care in hemodialysis patients.
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Estimating the effect of dialysis staffing ratio regulations on mortality and hospitalizations for Medicare hemodialysis patients Hemodial. Int. (IF 1.3) Pub Date : 2023-04-13 Allan Jacob, Conor Norris, Edward Timmons
Eight states and Washington, DC have implemented regulations mandating a minimum ratio between treatment staff and patients receiving hemodialysis in a facility in an effort to improve the quality of hemodialysis treatment. Our investigation examines the association between minimum staffing regulations and patient mortality for four states and hospitalizations for two states that implemented these
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Adaptation of home nocturnal hemodialysis for a patient with epidermolysis bullosa: A call to personalized care! Hemodial. Int. (IF 1.3) Pub Date : 2023-04-13 Rose Faratro, Christopher T. Chan
Epidermolysis bullosa (EB) is a genetic disease characterized by skin fragility presenting with blistering and skin erosions. Recurrent skin infections are noted to be associated with the pathogenesis of IgA nephropathy. End stage kidney disease (ESKD) is a rare complication in patients with EB (Ducret F., et al., Nephrol Ther, 2008). Kidney replacement therapy is very challenging in this vulnerable
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Association of vitamin D metabolites with arteriovenous fistula function in hemodialysis patients: A single center study Hemodial. Int. (IF 1.3) Pub Date : 2023-04-03 Hong Chen, Na Song, Ai-mei Li, Qin Dai, Yu-ting Liu, Shi-kun Yang
Arteriovenous fistula (AVF) is a primary dialysis vascular access commonly used for maintaining hemodialysis (MHD) patients. Vitamin D (VD) is a fat-soluble steroid hormone that is closely related to vascular endothelial function. This study aimed to investigate the association between VD metabolites and AVF failure in patients undergoing HD.
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Hemodialysis for an unusual occurrence of leptospirosis in a nonendemic region Hemodial. Int. (IF 1.3) Pub Date : 2023-04-03 Aziz Batu, Leman Karaagac, Tuncay Sahutoglu
Leptospirosis, an endemic zoonotic disease caused by Leptospira, is frequently seen in tropical regions and areas with low socioeconomic status. The disease can present a range of symptoms from mild to fatal, with potential involvement of multiple organs. This case report describes the treatment and clinical course of a 44-year-old male patient infected with Leptospira semeranga patoc 1 and presenting