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Acupuncture for Cyclic and Noncyclic Breast Pain in Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-03-18 Hangyu Shi, Huan Chen, Shuai Gao, Jiufei Fang, Lili Zhu, Zhishun Liu
Breast pain is a frequently encountered problem in both pre- and postmenopausal women. The pain can be severe and persistent and interferes with women's daily life. Acupuncture has been widely used for women with cyclic and noncyclic breast pain with possible favorable effect and few adverse events, however, the findings have not been systematically reviewed. This systematic review aims to investigate
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Interactions between vitamin D binding protein variants and major dietary patterns on mental health status in apparently healthy adults Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-03-11 Yasaman Nasir, Atiyeh Niknam, Mohammad Hossein Rahimi, Mahdi Molahosseini, Khadijeh Mirzaei
Recent studies have shown that the risks of mental disorders resulting from vitamin D deficiency, such as depression, anxiety and stress, can be affected by various high-risk alleles. Among the genes interacting with environmental factors are those associated with vitamin D binding protein (DBP) that affects the status of 25- OH vitamin D. Therefore, the present study aimed to determine the interaction
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Meta-analysis and network pharmacology-based investigation of Shenqi Fuzheng injection plus docetaxel for the efficacy and molecular mechanism of breast cancer Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-03-06 Yanqiong Luo, Yujiao Hou, Qian Li, Han Zhang, Moses Manaanye Njolibimi, Wenjing Li, Bo Hong
Breast cancer (BC), known as the "pink killer," with a high incidence and poor prognosis, is one of the most prevalent malignant tumors in women. Shenqui Fuzheng injectin (SFI), a kind of Chinese medicine immunomodulator, has the potential to enhance efficacy and reduce toxicity in treating BC in combination with docetaxel (DOC) because of its pharmacological effects of tonifying Qi and strengthening
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Kuntai capsule for the treatment of ovulatory disorder infertility: A systematic review and meta-analysis of randomized controlled trials Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-02-24 Xudong Zhang, Xue Bai, Lina Zhang, Ling Xiong, Juwen Zhang, Yun Li, Wenjing Chang, Wei Chen
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The effect of reflexology on pain, anxiety, fatigue, and sleep in patients undergoing coronary artery bypass graft surgery: A randomized controlled trial Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-02-22 Kubra Gunes, Elif Gezginci, Mustafa Tok
Reflexology is a non-pharmacological method that helps normalization of bodily functions by applying pressure to the reflex points on the hands, feet and ears, which correspond to all the organs and glands in the body. This study aimed to evaluate the effect of reflexology on pain, anxiety, fatigue, and sleep in patients undergoing cardiovascular surgery. This open-label, randomized parallel-group
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Exploring why individuals utilise naturopathic treatment and choose to combine naturopathy with biomedicine Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-02-22 Asmita Patel, Robyn Carruthers, Wayne Hill, Karen Wesseling, Karen Mees
There has been a global increase in the utilisation of traditional, complementary, and integrative medicine (TCIM), including that of naturopathy. Limited New Zealand research exists that has examined why individuals use naturopathic treatment, and why in some cases, naturopathy is combined with biomedicine. The present study had two main aims: (1) To identify why individuals utilise naturopathic treatment
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Integrating yoga into comprehensive cancer care: Starting somewhere Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-02-21 Kathryn M. Glaser, Christina R. Crabtree-Ide, Tessa F. Flores, Mary E. Reid
The rapid increase in cancer survivors in the United States (US) highlights the importance of survivors’ long-term care needs and symptom management. Given evidence that yoga supports cancer related symptoms, our aim was to develop and implement a community yoga program available for cancer survivors, family members, and staff involved in cancer care at a public comprehensive cancer center in the US
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Exploring the potential of Cytisus purgans as a source of bioactive molecules: In vitro pharmacological evaluation Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-02-21 Safa Chaira, Badra Bouzghaia, Mourad Hanfer, Imededdine Kaddi, Mohammed Tahar Ben Moussa, Patrick Pale, Hassina Harkat
is an uncommon species found in Algeria (Aures, Mahdids and Lella Khadidja). In the current study, we present, to the best of our knowledge, the first detailed chemical profile of its extracts and collect various pieces of evidence that underscore their therapeutic potential. The ethyl acetate extract (EAE) of was purified using different chromatographic methods. The bioactive compounds obtained were
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The add-on effect of oral East Asian herbal medicine to steroid therapy for alopecia areata: A systematic review and meta-analysis Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-02-17 Soojin Park, Jieun Lee, Seoyeon Jun, Kyuseok Kim
Alopecia areata (AA) is an autoimmune disease that degrades patient quality of life and adversely affects mental health. Since steroid therapy (ST) has limited efficacy and a risk of recurrence, East Asian herbal medicine (EAHM) combined with ST has been suggested as an alternative treatment. Many randomized controlled trials (RCTs) have been conducted on the efficacy of EAHM combined with ST in AA
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Development of an adverse event reporting template for Ephedrae Herba for weight loss Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-02-15 Soobin Jang, Mi Mi Ko, Bo Young Kim, Mi Ju Son, Kyung Hwan Jegal, Jeonghwan Park, Sungha Kim
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The effect of vitamin D supplementation in pregnancy on the incidence of preeclampsia: A systematic review and meta-analysis Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-02-11 Zainab Alimoradi, Farideh Kazemi, Azita Tiznobeik, Mark D. Griffiths, Seyyedeh Zahra Masoumi, Soodabeh Aghababaei
The results of previous studies on the effect of vitamin D on the incidence of preeclampsia are inconsistent. Therefore, the primary objective of the present review was to determine the effect of vitamin D supplementation during pregnancy on the risk of preeclampsia. Five major scientific databases were searched from inception to June 10, 2023. Studies with randomized controlled trial designs were
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Effect of transcutaneous electrical acupoint stimulation on sleep quality: A systematic review and meta-analysis Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-01-28 Jia-rui Zhang, Yi Ruan, Xin Wang, Yan-li You, Zi-fei Yin, Wei Gu
Introduction Poor sleep quality may have a negative effect on health. Clinical studies have assessed the ability of transcutaneous electrical acupoint stimulation (TEAS) to improve sleep quality. This review aims to explore the efficacy and safety of TEAS to improve sleep quality, as well as the most promising application scenarios for TEAS. Methods Eight databases were searched from their inception
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Chinese medicine practitioners’ consensus on traditional Chinese medicine diagnostic patterns, symptoms, and herbal formulas for COVID-19 survivors: A Delphi study Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-01-27 Jiayin Ruan, Shucheng Chen, Yuen Shan Ho, Vivian Taam Wong, Mei Yuk Lam, Hector Wing Hong Tsang, Ian Hoyin Cheng, Wing Fai Yeung
Introduction In April 2022, the “Guidance and recommendations on Chinese Medicine Rehabilitation during COVID-19 recovery stage (pilot version)” (the CM Rehabilitation Guidance) was formulated for Hong Kong COVID-19 survivors. However, no consensus regarding traditional Chinese medicine (TCM) diagnostic patterns, symptoms, and herbal formulas in the Guidance has been reached among Hong Kong Chinese
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Water Knotweed is an Important Candidate for Preclinical Trials with its High Photoprotection and Remarkable Bioactive Properties Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-01-27 Emine Bagdatli, Aliye Gediz Erturk
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Phytochemical profile by LC-MS/MS analysis and evaluation of antioxidant, antidiabetic, anti-Alzheimer, and anticancer activity of Onobrychis argyrea leaf extracts Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-01-20 Esma Yeniçeri, Ahmet Altay, Ekrem Koksal, Sevgi Altın, Parham Taslimi, Mustafa Abdullah Yılmaz, Oğuz Cakir, Abbas Tarhan, Ali Kandemir
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Combined Korean medicine therapies in children with allergic rhinitis: A prospective, multicenter, observational registry trial at primary-care network clinics Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-01-20 Hongmin Chu, EunKyoung Lee, Seunghwan Moon PharmB, Bo-Hyoung Jang, Donggil Shin, Hanjung Ryu, Yugoon Ha, YI JONGHOON, SunHee Haam, Baek-geon Jo, Byeong-kook Son, Sun-young Jang, Byoungho Lee, Ye-Jea Ahn, Sunghee Chang, Mu-jin Jeong, Mun-ok Hwang, Su-Jeong Jo, Mi-jeon Jung, Soo-jeong Eom, Hyug Yong Choi
Introduction Allergic rhinitis (AR) causes symptoms such as hyper-rhinorrhea, sneezing, nasal congestion, itching, and pain by triggering inflammation in the nasal mucosa and an immune response caused by antigen-specific Immunoglobulin E (IgE). This prospective multicenter observational study aimed to evaluate the symptoms change and safety of combined Korean medicine (KM) therapy in patients with
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Acupuncture for Parkinson's disease-related constipation: A systematic review and meta-analysis Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-01-06 Xin-Xin Feng, Lei Chen, Yong-Yi Xu, Kai Zhou, Kai-Yu Huang
Introduction The hazard of Parkinson's disease-related constipation (PDC) cannot be ignored. Acupuncture has the potential to become a mainstream treatment option for PDC. This review aimed to investigate the effect of acupuncture on PDC, which might provide evidence-based recommendations for clinical application. Methods Six databases were searched for randomized controlled trials (RCTs) about acupuncture
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Chinese herbal medicine Er-xian decoction for primary ovarian insufficiency: A systematic review of randomized controlled trials and meta-analyses Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-01-06 Zhefen Mai, Chunli Lu, Xinyan Jin, Zixun Zhuang, Lingjing Lu, Yu Su, Chun Luo, Xia Han, Shaochuan Huo, Hongxia Ma
Introduction The limitations of hormone therapy for managing primary ovarian insufficiency (POI) have promoted trialists to evaluate the Chinese herbal medicine, Er-xian decoction (containing Curculiginis Rhizome, Epimrdii Herba, Angelicae Sinensis Radix, Morindae Officinalis Radix, Phellodendri Chinrnsis Cortex and Anemarrhenae Rhizoma) in treating primary ovarian insufficiency (POI). This study was
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Evaluation of the effects of Bauhinia forficata as an adjuvant in the treatment of type 2 diabetes mellitus: systematic review and meta-analysis Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-01-05 Liliana Maria Dimer, Tamy Colonetti, Maria Laura Rodrigues Uggioni, Sarah Dagostin Ferraz, Antonio José Grande, Maria Inês da Rosa, Luciane Bisognin Ceretta
Introduction Type 2 diabetes mellitus (T2DM) is characterized by defects in insulin action and secretion. Bauhinia forficata has been observed to exhibit an effect in diabetes treatment due to its hypoglycemic activity. This systematic review with meta-analysis aimed to assess the effects of using Bauhinia forficata Link as an adjuvant treatment for individuals with T2DM. Methods We conducted a comprehensive
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Acupuncture for HIV/AIDs and its complications: A systematic review and meta-analysis Eur. J. Integr. Med. (IF 2.5) Pub Date : 2024-01-03 Zhi-Jie Wang, Lin-Lin Tan, Yu Zhang, Jia-Qi Yan, Jian-Ping Liu
Human immunodeficiency virus (HIV) has spread globally. Both acquired immune deficiency syndromes (AIDs) and its complications pose a serious threat to human health. Acupuncture has been reported as a complement to Western medicine for relieving HIV/AIDs-related symptoms, but systematic reviews on acupuncture for HIV/AIDs and its complications are lacking. Six databases were searched for both randomized
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Exploring the perceived benefits of a motivational exercise program (FIT-CANCER) in colorectal cancer patients during chemotherapy treatment: A qualitative study from self-determination theory Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-12-23 María Romero-Elías, David González-Cutre, Ana Ruiz-Casado, Roberto Ferriz, Natalia Navarro-Espejo, Vicente J. Beltrán-Carrillo
Introduction: Physical activity (PA) is considered an important factor to enhance the survival rate and overall quality of life in colorectal cancer (CRC) patients. However, a small percentage of patients comply with PA recommendations and most of them decrease their PA levels during chemotherapy. Theoretical frameworks could be useful for guiding exercise programs focused on the promotion of patients’
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Naturopaths’ approach to care of women with infertility: A cross-sectional survey Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-12-22 Alison Maunder, Susan Arentz, Mike Armour, Michael F Costello, Carolyn Ee
Introduction Infertility affects approximately one in six couples of reproductive age. Many women use traditional, complementary and integrative medicine to improve their chances of conceiving. While there is evidence of the use of naturopathy by women attempting to conceive, there is no evidence of the way that naturopaths approach and manage their treatment. This study aims to describe how naturopaths
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The Effects of Catgut Embedding in Patients with Obesity of Gastrointestinal Internal Heat: A Randomised Controlled Trial Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-12-17 Qingqing Zhu, Jian Cheng, Xiaolan Xu, Tangying Xu, Xingjiang Gu, Yun Xia, Lingzhen Mao, Nannan Hu, Yuexia Fang
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Selecting indicators of acupuncture service quality using analytic hierarchy process Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-12-16 Chao-Chan Wu, Chiung-Chen Ho, Kai-Chun Yang
Introduction : In traditional Chinese medicine (TCM) services, formulating management strategies and policies to improve service quality is essential for maintaining competitive advantages. The purpose of this study is to select key indicators of acupuncture service quality to assist in the development of relevant strategies in order to guide service management in TCM clinics. Methods : This study
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Effects of aromatherapy on anxiety in patients with cancer: A systematic review and meta-analysis of randomized controlled trials Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-12-16 Ju Hyun Ahn, Myoungsuk Kim
Introduction Patients with cancer often experience anxiety during cancer diagnosis and treatment, which can negatively impact their treatment outcomes. Although aromatherapy is believed to be effective in reducing anxiety in patients with cancer, the evidence has been limited. This review aimed to investigate the effectiveness of aromatherapy in reducing anxiety in patients with cancer and identify
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Network pharmacology, molecular docking and experimental verification reveal the mechanism of Yiguanjian decoction in treating acute liver failure Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-12-16 Shuai Wang, Yu Sun, Chunmei Zhang, Bohao Chen, Mei Zhong, Ruili Du, Yuhang Zhou, Guangdong Tong, Lidan Luo
Introduction: The potential targets and action mechanism of Yiguanjian (YGJ) decoction in treating acute liver failure (ALF) were determined using network pharmacology, molecular docking and cell experiments. Methods: The Pharmacology of Traditional Chinese Medicine Systems (TCMSP) and BATMAN-TCM databases were used to find YGJ decoction targets. The Genecard database was employed to predict targets
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Medical service utilization patterns among adults with insomnia: A retrospective cohort study Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-12-15 Min Kyung Hyun, Jang Won Lee
Patients with insomnia can use Korean medicine (KM) alongside conventional medicine (CM) as treatment options within the Korean healthcare system, but the treatment patterns for insomnia remain unclear. This study evaluated the incidence of newly diagnosed insomnia and medical service utilization, including untreated, CM, KM, and concurrent use of CM and KM, and the determinants of treatment after
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The efficacy and safety of Simiao Xiaobi decoction on rheumatoid arthritis: A systematic review and meta‑analysis Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-12-02 Soo-Yeon Chae, Seo-Hyun Park, Joo-Hee Kim, Eun-Jung Kim, Byung-Kwan Seo, Seong-Sik Park, Won-Suk Sung
Introduction Simiao Xiaobi decoction (SXD) is a traditional Chinese medicine (TCM) formula that has been clinically applied for rheumatoid arthritis (RA). This meta-analysis aimed to systematically assess the therapeutic efficacy and safety of SXD compared to conventional therapy. Methods Twelve worldwide databases were searched for randomized controlled trials (RCTs) of treating RA with SXD and comparing
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Clinical efficacy and safety of Shensong Yangxin capsule-antiarrhythmic drug combination for paroxysmal atrial fibrillation: A meta-analysis of randomized controlled trials Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-12-01 Xinfu Cao, Zhenhua Gu, Yi Sun, Yuqiao Chen, Chao Tang, Hongwen Yu, Xiaolong Li
Introduction Shensong Yangxin Capsule (SSYX) is a famous traditional Chinese patent medicine produced in China for the treatment of arrhythmia. Recently, China released a series of randomized controlled trials (RCTs) using SSYX combined with antiarrhythmic drugs (ADs) for the treatment of paroxysmal atrial fibrillation (PAF). However, these RCTs have not been systematically evaluated. The purpose of
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Outcomes for clinical research on Chinese medicine dampness syndrome: A protocol of developing a core outcome set Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-11-29 Xingying Qiu, Jun Tan, Wencong Cao, Zehuai Wen, Geng Li
Introduction Chinese medicine (CM) /integrative medicine has been widely used to treat dampness syndrome which has been regarded as the main pathogenesis of many chronic diseases. Many clinical trials of CM/integrative medicine for dampness syndrome have been conducted. However, most of their conclusions should be viewed with caution because of their methodological quality defects. One of the defects
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Efficacy and safety of Shengmai injection for chronic cor pulmonale: A systematic review with meta-analysis and trial sequential analysis of 31 randomized controlled trials Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-11-23 Xunxun Yuan, Xianjie Feng, Jun He, Sheng Xu, Xu Zhou, Lihua Wang
Introduction This study aimed to systematically evaluate the efficacy and safety of Shengmai injection (Radix ginseng, Radix ophiopogonis, and Fructus Schisandrae chinensis) as an adjunct to conventional medicine in the treatment of chronic cor pulmonale. Methods A search of ten databases was conducted up to March 27, 2023, to identify randomized controlled trials that assessed the efficacy of Shengmai
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Effects of Chinese herbal medicine on pregnancy outcomes of women with PCOS undergoing in vitro fertilization and embryo transfer: A retrospective cohort study Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-11-23 Minchen Dai, Biwei Shi, Xian Zhang, Yinger Gu, Fangfang Wang, Jue Zhou, Fan Qu
Introduction Chinese herbal medicine is widely used for treating polycystic ovary syndrome (PCOS). The present study aimed to explore the effects of Bu-Shen-Jian-Pi Formula, a Chinese herbal medicine formula, on the pregnancy outcomes of women with PCOS undergoing in vitro fertilization and embryo transfer (IVF-ET) based on a retrospective cohort study. Methods One hundred and forty-six females with
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Identification of drivers and affecting factors in the future of Persian medicine: The cross-impact analysis method Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-11-23 Mohammad Hossain Mehrolhassani, Mohammad Setayesh, Vahid Yazdi-Feyzabadi, Rohaneh Rahimisadegh
Introduction Persian medicine is a holistic medical school with deep roots. It has a high educational, research, and therapeutic capacity and has been the focus of Iran's general health policies in recent years. Futures studies aid policymakers and health managers in creating normative scenarios and developing action plans using various techniques. This study aimed to identify important drivers and
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Complex systems, complex practice, complex outcomes: A call for the development of complexity-informed implementation models (CIIM) for traditional, complementary, and integrative medicine. Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-11-03 Kim D. Graham, Hope Foley, Jon Adams, Amie Steel
Introduction Implementation science is the vehicle for ensuring that research evidence informs and shapes clinical practice. However, implementation models structured along linear and mechanistic lines are not necessarily aligned with the complexity of clinical practice. In this article we explore the development and value of a complexity informed implementation model primarily for use in traditional
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A cross-sectional study of reporting guidelines for clinical studies in Traditional Chinese Medicine Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-11-03 Yuting Duan, Zhirui Xu, Pinge Zhao, Juexuan Chen, Yanfang Ma, Lin Yu
Introduction Reporting guidelines (RGs) provide the minimum information for inclusion to ensure that research reports can be understood by readers, reproduced or otherwise utilized by other researchers, or guide decisions by clinicians. The Reporting Guidelines for Clinical Studies in Traditional Chinese Medicine (RGCS-TCM) were established to guide the development of reporting standardization of clinical
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Knowledge, attitude, and practice toward complementary alternative medicine in the UAE: A cross- sectional study Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-11-03 Yousef Aljawarneh, Lubna Rajab, Amani Alzeyoudi, Amnah Alzeyoudi, Amira Ibrahim, Noura Alnaqbi, Salha Alkaabi
Introduction Complementary and Alternative Medicine (CAM) encompasses utilization of traditional approaches in treating illnesses. The literature on CAM in the United Arab Emirates (UAE) shows varying awarness and practice. This study aimed to assess the knowledge, attitude, and practice towards CAM in the UAE. Methods The study utilized a cross-sectional design and collected data between January and
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A scoping review of traditional medicinal plants used to treat acne vulgaris in Türkiye Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-11-01 Fatma Sarı, Zeynep Büşra Erarslan
Introduction Acne vulgaris is one of the most common dermatological disorders, especially in adolescents. This study aimed to review medicinal plants used in the treatment of acne vulgaris in Türkiye which have comprehensive usage information. Methods Ethnobotanical studies conducted in Türkiye from 1990 to 2023 were identified through PubMed, Sciencedirect, Scopus, Google Scholar, and YOK National
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Machine learning-based evaluation of application value of traditional Chinese medicine clinical index and pulse wave parameters in the diagnosis of polycystic ovary syndrome Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-10-14 Jiekee Lim, Jieyun Li, Xiao Feng, Lu Feng, Xinang Xiao, Yumo Xia, Yiqin Wang, Lin Qian, Hong Yang, Zhaoxia Xu
Introduction Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in women that often leads to ovulatory infertility. This study aims to establish and validate an effective predictive model for PCOS and to explore the correlation of features between patients with irregular menstruation and those with PCOS, using pulse wave parameters and traditional Chinese medicine (TCM) clinical indices
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Bloodletting therapy for primary headache: A systematic review and meta-analysis of randomized controlled trials Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-10-14 Shuai Dong, Yi-Ying Wang, Bo Li, Shi-Bing Liang, Hui-Juan Cao
Introduction Headache is one of the most common symptoms worldwide. This systematic review aimed to assess the effectiveness and safety of bloodletting therapy (BLT) for primary headache. Methods Four English databases, four Chinese databases and five trials registries were searched from inception to 2nd Sep 2022. Randomized controlled trials which compared BLT to no treatment or drugs for primary
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Assessing the quality of complementary, alternative, and integrative medicine website information for cancer: A cross-sectional survey and analysis Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-10-11 Jeremy Y. Ng, Maheen Raja, Umair Tahir, Harmy Thakar, Sabrina L. Balkaran
Introduction Patients with cancer frequently utilize complementary, alternative, and integrative medicine (CAIM); prior to this, many seek information about these therapies online. Little is known about the quality of this web-based consumer health information. Our study aimed to address this paucity of research by evaluating the quality of CAIM consumer health information on websites discussing the
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Homeopathy as patient empowerment and an active path toward supportive care for non-metastatic breast cancer: A qualitative study (TOUCAN) Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-10-05 Clair-Antoine Veyrier, Guillaume Roucoux, Laurence Baumann-Coblentz, Jacques Massol, Jean-Claude Karp, Jean-Philippe Wagner, Olivier Chassany, Martin Duracinsky
Introduction Breast cancer is the leading cause of death among French women, although the survival rate is increasing thanks to therapy and supportive care. Homeopathy is one of most widely used non-conventional supportive approaches in this context. This article aims to describe the ways women with non-metastatic breast cancer integrate homeopathy as supportive care into their conventional therapy
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The effect of aromatherapy and music therapy upon anxiety and non-stress test results during pregnancy: A randomized clinical trial Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-09-29 Nasrin Rezaei, Maryam Keshavarz, Sally Pezaro, Fatemeh Sarvi, Nooshin Eshraghi, Reza Bekhradi
Introduction The non-stress test (NST) is commonly recommended for assessing fetal wellbeing. Anxiety in pregnancy can affect NST results and thus rates of false-positive results can increase. This study aimed to explore whether lavender oil inhalation administered in conjunction with music therapy is more effective in reducing anxiety and NST results during pregnancy than the use of lavender oil alone
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Evidence-based traditional medicine for transforming global health and well-being Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-09-25 Bhushan Patwardhan, L. Susan Wieland, Obijiofor Aginam, Anchalee Chuthaputti, Ricardo Ghelman, Roshanak Ghods, Goh Cheng Soon, Motlalepula G. Matsabisa, Georg Seifert, Sione Tu'itahi, Kim Sung Chol, Shyama Kuruvilla, Kathi Kemper, Holger Cramer, H.R. Nagendra, Anup Thakar, Tanuja Nesari, Sanjeev Sharma, Narayanam Srikanth, Rabinarayan Acharya
Abstract not available
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Moxibustion for chemotherapy-induced myelosuppression: A systematic review and meta-analysis Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-09-09 Xiao-Qing Wang, Yue Qiao, Yuan-Yuan Zhang, Li-Hua Yang, Pei-Bei Duan
Introduction Myelosuppression is a common treatment-related complication in cancer patients. Moxibustion has been proposed as a potentially effective intervention to alleviate the side effects of chemotherapy-induced myelosuppression. This review aimed to investigate the effectiveness and safety of moxibustion in treating chemotherapy-induced myelosuppression, as well as the most promising modalities
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Study protocol for a preliminary optimization trial of transcutaneous electrical acupoint stimulation device simulating acupuncture Deqi Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-09-09 Jie-Dan Mu, Zhou Zhang, Liang-Xiao Ma, Han-Lei Li, Xiao-Shan Huang, Xue Li, Xu Qian, Ling-Hui Ma, Qin-Yong Zhang, Tian-Yi Sun
Introduction Transcutaneous electrical acupoint stimulation (TEAS) is a treatment approach derived from acupuncture but with better efficacy, safety, and non-invasiveness. It is, therefore, increasingly used in clinical practice. Traditionally, Deqi is considered a positive response of the body to acupuncture-like stimulation and essential for the efficacy of acupuncture. We hypothesized that applying
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Factors associated with willingness to receive acupuncture in patients with major traumatic injuries: A qualitative study Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-09-02 Dahye Lee, Moon Joo Cheong, Seon Hee Kim, Hyun Min Cho, Jungtae Leem, Chi Hyoung Son, Yu Kyung Shin, Kun Hyung Kim
Introduction Patients with major traumatic injuries experience chronic pain, diminished daily and social functions, and impaired quality of life. Acupuncture is regularly used for managing chronic pain and long-term disabilities in South Korea. However, little information is available on its use by patients after major traumatic injuries. This study aims to explore how patients’ willingness to receive
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Development and multiple visualization methods for the therapeutic effects prediction model of five-flavor Sophora Flavescens enteric-coated capsules in the treatment of active ulcerative colitis: A study on model development and result visualization Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-09-02 Zhi-Jun Bu, Zhi-Rui Huang, Yun-Ru Chen, You-Zhu Su, Yuan-Yuan Jin, Yu-Huan Zhang, Qiu-Ju Wu, Xue-Hui Wang, Yu Wang, Jian-Ping Liu, Zhao-Lan Liu
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Chinese herbal medicine for primary dysmenorrhea: A systematic review and network meta-analysis of 54 randomized controlled trials Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-19 Xinbin Wang, Zhongwen Zhang, Haorui Wang, Ruilin Ma, Lili Wang, Xianhui Zhang, Yi Zhang, Rong Wang
Introduction Primary dysmenorrhea (PD) is a common gynecological complaint among adolescents and young women. Chinese herbal medicines (CHMs) have been widely used for PD treatment in China. However, the relative advantages of different CHM regimens remain uncertain. This systematic review aimed to compare the efficacy and safety of different CHMs for the treatment of PD using network meta-analysis
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Attitudes and beliefs towards the use of complementary and alternative medicine in cancer patients Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-18 Mohamed Aboufaras, Karima Selmaoui, Nadia Ouzennou
Introduction Complementary and alternative medicine (CAM) use is significantly influenced by patient attitudes and beliefs. However, in Morocco, there is a lack of research specifically focusing on examining these attitudes and beliefs, which might differ in the local context. This study's main objective was to describe the attitudes and beliefs of cancer patients towards CAM and to identify the factors
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Effectiveness and safety of the combination of Chinese herbal medicine and acupuncture for women with polycystic ovarian syndrome: A systematic review and meta-analysis of randomized controlled trials Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-18 Xing-yan Liang, Chun-li Lu, Yu Su, Xin-yan Jin, Mu-lian Wu, Yao Lu, Yu Zhou, Zi-xun Zhuang, Chun Luo, Hong-xia Ma
Introduction This systematic review aimed to evaluate the effectiveness and safety of Chinese herbal medicine (CHM) plus acupuncture for women with polycystic ovarian syndrome (PCOS). Methods We searched for eligible randomized controlled trials (RCTs) in nine Chinese and English databases from their inception to May 7, 2023. The Cochrane “Risk of bias” tool and the Grading of Recommendations Assessment
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Effect of aromatherapy on postoperative pain relief: A systematic review and meta-analysis of randomized controlled trials Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-15 Peijia Zhang, Xin Liao, Qi Yuan, Fengqiong LYU, Shenghua Xie
Introduction Postoperative pain is very common in patients. Aromatherapy has been used to relieve postoperative pain. This systematic review and meta-analysis evaluated the effect of aromatherapy on postoperative pain and relevant physical and psychological outcomes in adults. Methods Eight databases were searched up to November 28, 2022 for randomized controlled trials (RCTs) on postoperative pain
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Use of Chinese herbal medicines for acute cough in China: An online survey Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-15 Ruyu Xia, Xiaoyang Hu, Michael Moore, Beth Stuart, Lingzi Wen, Bertrand Graz, Jianping Liu, Merlin Willcox, Yutong Fei
Introduction Anti-microbial resistance is a complex and evolving global public health threat. Promoting effective alternative treatments is an important way to reduce the unnecessary use of antibiotics. This study aimed to identify the use of treatments for acute cough in China, including Chinese herbal medicines (CHMs) and their association with avoidance of antibiotics and participants’ reported
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Phytochemical analysis and biological activity of Corchorus olitorius L.: Quantitative analysis of bioactive compounds by LC–MS/MS, antibacterial, enzyme inhibition, and cytotoxic activities Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-15 Mehmet Nuri Atalar, Ramazan Erenler, Fikret Turkan, Mehmet Hakki Alma, Ibrahim Demirtas, Ayse Baran, Sevgi Irtegun Kandemir, Ayse Ilgin Kekec, Fatma Zerrin Saltan
Introduction Corchorus olitorius L. is a significant plant in folk medicine, therefore, research on phytochemistry with biological activity may reveal its potential use in drug development. Medicinal plants are valuable sources of drug materials as they include bioactive compounds known as secondary metabolites. Determination of bioactive compounds and biological activity of plants lead to understanding
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The effect of ear acupressure on sexual functioning among lactating women: A randomized sham controlled trial Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-06 Zainab Alimoardi, Sanaz Barghamadi, Terry Oleson, Mohammad Hossein Ayati, Mark D. Griffiths, Nasim Bahrami
Introduction Women often experience more problems in sexual functioning after childbirth. Due to the high prevalence of sexual problems during the lactation period, the World Health Organization suggested measures are needed to improve women's sexual functioning during breastfeeding. The present study investigated the effect of auricular acupressure on sexual functioning among lactating women. Methods
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TCM syndrome classification using graph convolutional network Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-05 Shenghua Teng, Amin Fu, Weikai Lu, Chang'en Zhou, Zuoyong Li
Introduction Traditional Chinese Medicine (TCM) diagnosis is a reasoning process through expert knowledge, in which syndrome classification is a key step for prescription recommendation and the treatment of patients. Doctors generally differentiate syndrome types according to patients’ symptoms and state elements. This paper proposes a syndrome classification method based on graph convolutional network
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Efficacy and safety of Gelanxinning Soft Capsules (a Chinese patent medicine) for angina pectoris: A meta-analysis of randomized controlled trials Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-05 Meng Qiao, Chaoren Tan, Qiang Zhang, XiaoXiao Zhao, Chao Lei, YanMing Xie, ZhiFei Wang
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Chinese herbal medicine Shufeng Jiedu Capsule for patients with mild to moderate coronavirus disease 2019 (COVID-19): Protocol for a randomized, blinded, placebo control trial Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-04 Chun-li Lu, Liu-qing Yang, Xue-han Liu, Xin-yan Jin, Fu-xiang Wang, Thomas Friedemann, Nicola Robinson, Sven Schröder, Hong-zhou Lu, Jian-ping Liu
Introduction Most current Coronavirus disease (COVID-19) infected cases are now diagnosed as mild to moderate. Symptoms such as sore throat, headache, nasal congestion, cough, etc. lack effective treatment for their relief. The registered Chinese herbal medicine Shufeng Jiedu Capsule (SFJD) has been used to treat different epidemics like influenza A virus subtype H1N, and has been shown to improve
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Efficacy of Plantago major leaf extract cream compared to placebo in preventing acute radiodermatitis in breast cancer patients: A randomized clinical trial Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-02 Zahra Salehi, Ali Tavakoli, Seyed Hassan Hamedi, Soodabeh Samimi, Foroogh Namjooyan, Mansour Ansari, Hamid Nasrollahi, Nezhat Khanjani, Niloofar Ahmadloo, Ahmad Mosalaei, Behnam Kadkhodaei, Hossein Molavi Vardanjani, Mehrab Sayadi
Introduction Dermatitis is a common side effect of radiotherapy (RT). Plantago major L. leaves (P. major) exhibit anti-inflammatory and wound-healing activities. This study aimed to evaluate the preventive effect of P. major on acute radiodermatitis in breast cancer patients. Methods This randomized controlled trial involved 78 breast cancer patients who had undergone modified radical mastectomy and
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Clinical effects of Baduanjin qigong exercise on cancer-related fatigue: A systematic review and meta-analysis Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-08-02 QianQian Liu, LiuYan Zhan, Xue Yan, Yao Li, SiQi Wei
Introduction A number of randomized controlled trials have investigated the benefits of Baduanjin qigong on cancer-related fatigue (CRF) in cancer survivors. However, the results of these studies were inconclusive and contradictory, due to the limitations of small sample sizes and different measurement scores. We conducted this systematic review and meta-analysis of the evidence available to critically
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Dose-response associations between leisure-time physical activity and blood pressure control among treated hypertensive adults: A cross-sectional study from NHANES 2007–2018 Eur. J. Integr. Med. (IF 2.5) Pub Date : 2023-07-30 Yijian Ding, Xi Xu
Introduction The additive effects of physical activity on antihypertensive drugs are not fully understood. This study aimed to analyze the dose-response associations between leisure-time physical activity (LTPA) and blood pressure (BP) control, inflammation and oxidative stress regulation in treated hypertensive adults. Methods A total of 8269 treated hypertensive adults were included from the 2007