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Vaporized D-Limonene Selectively Mitigates the Acute Anxiogenic Effects of Δ9-Tetrahydrocannabinol in Healthy Adults Who Intermittently Use Cannabis Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-13 Tory R. Spindle, C. Austin Zamarripa, Ethan Russo, Lauren Pollak, George Bigelow, Alexandra M. Ward, Bridget Tomspon, Cristina Sempio, Touraj Shokati, Jost Klawitter, Uwe Christians, Ryan Vandrey
Cannabis contains hundreds of chemical constituents beyond Δ-9-tetrahydrocannabinol (THC), which is believed to drive most of its acute pharmacodynamic effects. The entourage effect theory asserts that non-THC constituents can impact acute cannabis effects, but few empirical studies have systematically evaluated this theory in humans. This study assessed whether the cannabis terpenoid d-limonene mitigates
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Methodological considerations when assessing symptoms of nicotine dependence by cigarette and e-cigarette use behavior and brand Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-13 Floe Foxon, Saul Shiffman
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Different measures of alcohol use as predictors of DSM-5 alcohol use disorder among adolescents – A cohort study from Sweden Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-12 Jonas Raninen, Patrik Karlsson, Sarah Callinan, Thor Norström
This study addresses a significant gap in existing research by investigating the longitudinal relationship between various measures of alcohol use and the development of alcohol use disorders (AUDs) in a cohort of Swedish adolescents. A prospective longitudinal survey was conducted on 3,999 adolescents in Sweden who were in 9th grade in 2017 and were followed up in 2019. Baseline assessments included
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Quantity of cigarettes smoked when co-used with alcohol and cannabis: Consideration of different definitions of co-use based on daily diary data Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-12 Joseph JC Waring, Nhung Nguyen, Pamela Ling, Johannes Thrul
Cigarettes are frequently co-used with alcohol and cannabis. However, definitions of co-use vary and the extent to which cigarette use changes on days with different patterns of co-use is unclear. We compared the number of cigarettes smoked on different days based on co-use patterns of cigarettes and alcohol or cannabis. This study analyzed 2,408 smoking days collected in a 30-day smartphone-based
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Correlates of overdose among 2,711 people who use drugs and live in 7 rural US sites Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-08 Fadanelli Monica M, Livingston Melvin “Doug”, Friedmann Peter, Go Vivian, Jenkins Wiley, Korthuis Todd, Miller William, Pho Mai, Seal David, Stopka Tom, Westergaard Ryan, Zule William, Young April M, Cooper Hannah LF
Overdose rates in rural areas have been increasing globally, with large increases in the United States. Few studies, however, have identified correlates of non-fatal overdose among rural people who use drugs (PWUD). The present analysis describes correlates of nonfatal overdose among a large multistate sample of rural PWUD. This is a cross-sectional analysis of data gathered via surveys with PWUD recruited
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Attitudes toward extended-release naltrexone treatment for opioid use disorder among African Americans Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-08 Khary K. Rigg
Extended-release naltrexone (XR-NTX; Vivitrol®) is a long-acting injectable form of naltrexone, which is a medication used to treat opioid use disorder (OUD). In 2010, XR-NTX received Food and Drug Administration approval to treat OUD, becoming the first non-addictive and non-psychoactive medication for this condition. Because uptake of XR-NTX has been relatively low, less is known regarding how persons
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Measurement of Cigarette Relighting: A Common but Understudied Behavior Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-06 William J. Young, Michelle Kennedy, Olivia A. Wackowski, Anna Mitarotondo, Maame Araba Assan, Daniel Scalia, Irina Stepanov, Michael B. Steinberg, Carolyn J. Heckman
Relighting, i.e., extinguishing, saving, and later relighting and smoking unfinished cigarettes, appears prevalent, may be associated with nicotine dependence and negative health outcomes, yet is poorly understood. We estimate the prevalence, frequency, correlates of, and reasons for, cigarette relighting. Survey respondents (n=676) were 18-45-year-old US-based Amazon Mechanical Turk (MTurk) participants
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Interpersonal Trauma, Shame, and Substance Use: A Systematic Review Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-06 Prachi H. Bhuptani, Yongkuan Zhang, Lauran Danzey, Aanandita Bali, Kirsten Langdon, Lindsay M. Orchowski
Interpersonal trauma is a risk factor for a wide array of adverse mental health outcomes, including substance use. Research has begun investigating the role of shame in the intersection between substance use and interpersonal trauma. The current systematic review summarizes the existing literature documenting the relation among shame, substance use, and interpersonal trauma. Articles were collected
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Medical-Surgical Patients with Untreated Hazardous Drinking: Randomized Controlled Trial of the DO-MoST Intervention to Improve Health Outcomes over 12-Month Follow-Up Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-05 Christine Timko, Kathryn Macia, Mandy Lewis, Mai Chee Lor, Daniel Blonigen, Mary Jannausch, Mark Ilgen
High prevalence and harmful consequences of hazardous drinking among medical-surgical patients underscore the importance of intervening with drinking to improve patients’ health. This study evaluated a novel intervention, “Drinking Options - Motivate, Shared Decisions, Telemonitor” (DO-MoST). In a randomized design, 155 medical-surgical patients with untreated hazardous drinking were assigned to enhanced
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Prevalence of cigarette use and addiction among Chinese females by age and province: Findings from nationwide China Health Literacy Survey during 2018-19 Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-05 Xin Xia, Ying-hua Li, Yi Liu, Zheng Su, Rui Qin, Zhao Liu, Ying Xie, Zhen-xiao Huang, Xin-mei Zhou, An-qi Cheng, Jin-xuan Li, Xiao-wen Wei, Qing-qing Song, Liang Zhao, Dan Xiao, Chen Wang
The prevalence of cigarette smoking among women is significantly different from that of men, however, cigarette use by women is little known. The study aims to describe cigarette use prevalence and patterns among Chinese females by age and province. This study was based on the 2018 China Health Literacy Survey (2018 CHLS), a nationally representative cross-sectional study, and our analysis included
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Multi-modal neuroimaging reveals differences in alcohol-cue reactivity but not neurometabolite concentrations in adolescents who drink alcohol Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-02 Anna E. Kirkland, ReJoyce Green, Brittney D. Browning, Stephanie Aghamoosa, Dieter J. Meyerhoff, Pamela L. Ferguson, Rachel L. Tomko, Kevin M. Gray, Lindsay M. Squeglia
The objective of this multi-modal neuroimaging study was to identify neuroscience-informed treatment targets for adolescent alcohol use disorder (AUD) by examining potential neural alterations associated with adolescent alcohol use. Adolescents (ages 17–19) who heavily used (n=49) or did not use alcohol (n=22) were recruited for a multi-modal neuroimaging protocol, including proton magnetic resonance
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Nine-year substance use treatment outcomes with buprenorphine for opioid use disorder in a federally qualified health center Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-03-02 Marwan Haddad, Emil Coman, Lauren Bifulco
Prescribing medication for opioid use disorder (MOUD) in primary care helps meet treatment demand, but few studies examine long-term treatment retention among medically-underserved primary care patients. This 9-year retrospective study assessed overall retention at 6 months, and yearly up to 9 years, among 1451 patients with at least 6 months of buprenorphine prescription data from a federally-qualified
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Unmet need for medication for opioid use disorder among persons who inject drugs in 23 U.S. cities Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-28 Senad Handanagic, Dita Broz, Teresa Finlayson, Dafna Kanny, Cyprian Wejnert, The NHBS Study Group
Persons who inject drugs (PWID) are at increased risk of HIV and hepatitis C virus (HCV) infections and premature mortality due to drug overdose. Medication for opioid use disorder (MOUD), such as methadone or buprenorphine, reduces injecting behaviors, HIV and HCV transmission, and mortality from opioid overdose. Using data from National HIV Behavioral Surveillance, we evaluated the unmet need for
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Association between non-medical cannabis legalization and alcohol sales: Quasi-experimental evidence from Canada Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-27 Shweta Mital, Lisa Bishop, Shawn Bugden, Paul Grootendorst, Hai V. Nguyen
There is increasing interest in understanding the impact of non-medical cannabis legalization on use of other substances, especially alcohol. Evidence on whether cannabis is a substitute or complement for alcohol is both mixed and limited. This study provides the first quasi-experimental evidence on the impact of Canada’s legalization of non-medical cannabis on beer and spirits sales. We used the interrupted
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Alcohol consumption and dependence risk among male and female Veterans: Trajectories and predictors Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-25 Brittany M. Mathes Winnicki, Daniel J. Lee, Sage E. Hawn, Nicholas A. Livingston, Brian P. Marx, Terence M. Keane
With few exceptions, previously conducted research on hazardous drinking among Veterans has employed samples in which the majority of participants identify as male. In addition, past studies have solely focused on alcohol consumption, rather than associated risk for dependence. In this study, we expanded upon the extant literature by investigating sex differences in trajectories and predictors of change
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3,4-Methylenedioxymethamphetamine (MDMA) impairs cognitive function during withdrawal via activation of the arachidonic acid cascade in the hippocampus Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-24 Yoko Nawata, Tsuyoshi Nishioku, Tsuneyuki Yamamoto, Taku Yamaguchi
The recreational drug ±3,4-methylenedioxymethamphetamine (MDMA; also known as “ecstasy”) has unusual subjective prosocial and empathogenic effects, and has exhibited potential as an adjunct to psychotherapy in recent years. However, there has been some concern regarding possible neuropsychiatric symptoms, such as cognitive impairment and dependence, emerging after abstinence. Therefore, this study
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“I want to stay here”: Patient and staff perspectives on transitioning from a low-threshold buprenorphine program to clinic-based care Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-23 Noelle G. Martinez, Ashley Q. Truong, Courtney D. Nordeck, Deborah Agus, Becky L. Genberg, Megan E. Buresh
The Project Connections At Re-Entry (PCARE) Van is a low-threshold buprenorphine program operating outside the Baltimore City Detention Center. Like other low-threshold programs, PCARE seeks to engage a vulnerable population in care, stabilize patients, then transition patients to longer-term care; however, <10% of patients transition to clinic-based buprenorphine treatment. Our goal was to better
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Erratum to “Effects of ambient temperature on locomotor activity and place conditioning elicited by abused psychostimulants in mice: Role of 3,4-methylenedioxy moiety” [Drug Alcohol Depend. 250 (2023) 110917] Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-23 Brenda M. Gannon, Lauren R. Fitzgerald, Christopher O. Godwin, Heidi D. Hughes-Meredith, Kenner C. Rice, William E. Fantegrossi
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PrEP for people who use opioids: A NIDA clinical trials network survey study in Southern U.S. cities where HIV incidence is high Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-23 Mary A. Hatch, Tanja C. Laschober, Margaret Paschen-Wolff, Melissa M. Ertl, C. Mindy Nelson, Lynette Wright, Chloe Lancaster, Daniel J. Feaster, David Forrest, Colby Hankey, Mauda Monger, Joshua P. Fegley, Rhonda Irving, Cynthia Young, Juliana Rose, Anya Spector, Lauren Dresser, Landhing Moran, Eve Jelstrom, Susan Tross
People who use opioids (PWUO) are at increased risk for HIV. Pre-exposure prophylaxis (PrEP) is effective but underutilized as HIV prevention among PWUO. This study examined predictors of willingness to take daily oral PrEP and long-acting injectable (LAI) PrEP among PWUO across eight Southern urban cities with high HIV incidence. HIV-negative PWUO ( = 308) seeking services in community-based programs
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Prevalence and reasons for use of heated tobacco products among Malaysian adults who smoked: Findings from the 2020 International Tobacco Control Malaysia Survey Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-17 Muhamad Alfakri Mat Noh, Farizah Mohd Hairi, Amer Siddiq Amer Nordin, Anne Yee, Nur Amani Ahmad Tajuddin, Siti Idayu Hasan, Mahmoud Danaee, Ina Sharyn Kamaludin, Muniswary Subramaniyan, R. Pravinassh, Susan C. Kaai, Pete Driezen, Mi Yan, Steve S. Xu, Anne C.K. Quah, Geoffrey T. Fong
There have been rapid expansions in heated tobacco products (HTPs) outside of Japan and the Republic of Korea. In November 2018, HTPs were first introduced in Malaysia and since then, no studies have been conducted on Malaysians’ use of HTPs. This study is the first to examine the prevalence of HTP use and reasons for use among Malaysian adults who smoked cigarettes. Data came from the 2020 ITC Malaysia
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Co-delivery of HIV pre-exposure prophylaxis (PrEP) and HIV testing among publicly insured adolescents and young adults (AYA) receiving medication for opioid use disorder (MOUD) Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-17 MC Herrera, J. Johnson, S. Lim, KH Morales, J.Deanna Wilson, SE Hadland, D. Metzger, S. Wood, N. Dowshen
Low rates of HIV pre-exposure prophylaxis (PrEP) prescribing contribute to the disproportionate burden of HIV in the United States. Among adolescent and young adults (AYA) with opioid use disorder, HIV testing and PrEP co-prescription rates are poorly characterized. We performed a retrospective analysis involving deidentified data from Philadelphia’s Medicaid beneficiaries ages 16–29 years who were
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Nicotine use among reservation-area American Indian adolescents compared with a national sample Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-15 Meghan A. Crabtree, Linda R. Stanley, Richard A. Miech, Randall C. Swaim
Past research has found significant nicotine use disparities for reservation-area American Indian adolescents when compared to national levels. However, adolescent nicotine use has changed markedly, with reduced smoking and rapid increases in nicotine vaping. This study presents 2021–2022 prevalence estimates of tobacco product use, perceived harm and availability for reservation-area American Indian
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Loci on chromosome 20 interact with rs16969968 to influence cigarettes per day in European ancestry individuals Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-15 Pamela N. Romero Villela, Luke M. Evans, Teemu Palviainen, Richard Border, Jaakko Kaprio, Rohan H.C. Palmer, Matthew C. Keller, Marissa A. Ehringer
The understanding of the molecular genetic contributions to smoking is largely limited to the additive effects of individual single nucleotide polymorphisms (SNPs), but the underlying genetic risk is likely to also include dominance, epistatic, and gene-environment interactions. To begin to address this complexity, we attempted to identify genetic interactions between rs16969968, the most replicated
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Expanding access to medication treatment for opioid use disorders: Findings from the Washington State hub and spoke effort Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-14 Maureen T. Stewart, Shay M. Daily, Cindy Parks Thomas, Lee Panas, Grant Ritter, Sharon Reif
Opioid use disorder (OUD) is a leading cause of preventable death and injury nationwide. Efforts to increase the use of medication for opioid use disorder (MOUD) are needed. In 2017, Washington State implemented a Hub and Spoke (HS) model of care with the primary goal of expanding access to MOUD. We examined changes in MOUD utilization among Washington State Medicaid beneficiaries before and after
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Comparative analysis between CDT in serum and Ethyl glucuronide in hair to define the best reliable tool for the diagnosis of alcohol abuse Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-14 Alice Cerioni, Erika Buratti, Gianmario Mietti, Isabella Lima Arrais Ribeiro, Marta Cippitelli, Giovanna Tassoni, Mariano Cingolani, Rino Froldi, Roberto Scendoni
The increase in alcohol consumption in society has not only led to a number of medical problems but has also become a problem of considerable legal importance. Thus, there is both scientific interest and the necessity to diagnose alcohol abuse in the application of the provisions of the law through laboratory tests that ensure maximum objectivity. The purpose of this work is to study and compare the
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Learning with conviction: Exploring the relationship between criminal legal system involvement and substance use and recovery outcomes for students in collegiate recovery programs Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-13 Noel Vest, Justin S. Bell, Alexa Nieder, Rebecca Smith, Thomas Bannard, Sarah Tragesser, Patrick Hibbard, Danielle M. Dick
This study examines the association of criminal legal system involvement and age with substance use and academic related outcomes among students involved in collegiate recovery programs in the US. We examined 435 students in collegiate recovery using a national survey of college students. We computed differences between non-system-involved, system-involved with no incarceration history, and formerly
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Anterior cingulate and medial prefrontal cortex alcohol cue reactivity varies as a function of drink preference in alcohol use disorder Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-12 Dylan E. Kirsch, Lara A. Ray, Kate M. Wassum, Erica N. Grodin
Functional MRI visual cue reactivity studies have not considered that brain responses to various alcohol-containing beverage types may vary as a function of an individual’s drinking patterns and preferences. This study tested whether the brain’s reward system responds differently to visual cues associated with an individuals’ most commonly consumed (“preferred”) alcohol beverage compared with less
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Comparison of transdermal alcohol concentration and self-reported alcohol consumption in people with alcohol dependence attending community alcohol treatment services Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-11 Eileen Brobbin, Paolo Deluca, Simon Coulton, Stephen Parkin, Colin Drummond
We aimed to assess the accuracy and wearability of a transdermal alcohol sensor (TAS) (BACtrack Skyn) with people currently receiving treatment at alcohol services. A mixed methods observational study involving three NHS alcohol services in south London was conducted. All participants (7=male, 9=female) wore a TAS for 1 week and met with the researcher every other weekday to complete the TAS data download
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Mobile health intervention to address chronic pain among those who engage in hazardous drinking: A pilot study Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-10 Tibor P. Palfai, Natalia E. Morone, Maya P.L. Kratzer, Grace E. Murray, John D. Otis, Stephen A. Maisto, Bonnie H.P. Rowland
Hazardous drinking has been associated with chronic pain in community and medical samples. The purpose of this study was to develop a novel, integrated mobile health intervention that improves pain management and reduces hazardous drinking that may be implemented in primary care settings. Forty-eight participants with moderate or greater chronic pain and hazardous drinking were recruited from primary
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A qualitative study to determine perspectives of clinicians providing telehealth opioid use disorder treatment Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-08 Barbara Burke, Emily Miller, Brian Clear, Scott G. Weiner
Telehealth-only medication for opioid use disorder (teleMOUD) treatment with buprenorphine was first made possible in the United States during the COVID-19 Public Health Emergency. As a result, several large provider groups now treat opioid use disorder (OUD) patients in nearly every state using telehealth. This study evaluates the perceptions and experiences of providers working almost exclusively
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Derived psychoactive cannabis products and 4/20 specials: An assessment of popular brands and retail price discounts in Fort Worth, Texas, 2023 Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-07 Matthew E. Rossheim, Cassidy R. LoParco, Carla J. Berg, Kayla K. Tillett, Pamela J. Trangenstein, Doug Henry, R. Andrew Yockey, M. Doug Livingston, David H. Jernigan, Steven Y. Sussman
Retail sales of derived psychoactive cannabis products (DPCPs) have increased in the U.S. since passing the 2018 Farm Bill and is unregulated in most states. This study investigated the types and commonly sold brands of DPCPs as well as promotional pricing on April 20, a day associated with cannabis use. On April 19-20, 2023, investigators conducted telephone surveys with 98 retail stores that sold
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Exploring patterns of alcohol use and alcohol use disorder among Asian Americans with a finer lens Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-07 Haitao Zhang, W. June Ruan, S. Patricia Chou, Tulshi D. Saha, Amy Z. Fan, Boji Huang, Aaron M. White
National survey data suggest Asian Americans (AA) are less likely to consume alcohol and develop AUD than Americans in other groups. However, it is common for AA to be born outside of the US and carry gene variants that alter alcohol metabolism, both of which can lead to lower levels of alcohol involvement. The current study examined differences in alcohol use and AUD between AA and other groups before
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National and regional trends in seizures of shrooms (psilocybin) in the United States, 2017–2022 Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-06 Joseph J. Palamar, Nicole D. Fitzgerald, Thomas H. Carr, Caroline Rutherford, Katherine M. Keyes, Linda B. Cottler
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Clinical cutoffs of the Alcohol Use Disorder Identification Test for identification of DSM-5 alcohol use disorder: A psychometric evaluation in treatment-seeking patients Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-05 S. Ingesson-Hammarberg, O. Molander, A. Hammarberg
The AUDIT is considered a gold-standard self-rating instrument used in various settings for the identification of alcohol use disorders. Although the AUDIT is widely used, there is not yet a consensus concerning the clinical cutoff for the identification of an alcohol use disorder according to the DSM-5. The current study aimed to investigate the optimal gender-based cutoffs on both AUDIT and AUDIT-C
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Trajectories of alcohol and cannabis use among emerging adults with a history of unstable housing: Associations with functioning over a two-year period Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-03 Joan S. Tucker, Anthony Rodriguez, Elizabeth J. D’Amico, Eric R. Pedersen, Rupa Jose, David J. Klein
Research has documented high rates of alcohol and cannabis use among emerging adults experiencing homelessness. However, little is known about trajectories of use over time or how trajectories are associated with functioning (e.g., risk behaviors, mental and physical health, social functioning, economic well-being). Data come from a cohort of 18-25 year olds experiencing homelessness who were surveyed
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DNA methylation at DLGAP2 and risk for relapse in alcohol dependence during acamprosate treatment Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-03 Fatih Özel, Michela Di Criscio, Diana Ioana Lupu, Daniil Sarkisyan, Ryan A. Hlady, Keith D. Robertson, Georgy Bakalkin, Yun Liu, Joanna M. Biernacka, Victor M. Karpyak, Tomas J. Ekström, Joëlle Rüegg
Alcohol use disorders are prevalent mental disorders with significant health implications. Epigenetic alterations may play a role in their pathogenesis, as DNA methylation at several genes has been associated with these disorders. We have previously shown that methylation in the gene, coding for a synaptic density protein, is associated with alcohol dependence. In this study, we aimed to examine the
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Associations between cannabis policies and state-level specialty cannabis use disorder treatment in the United States, 2004–2019 Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-02 Pia M. Mauro, Sarah Gutkind, Melanie S. Askari, Deborah S. Hasin, Hillary Samples, Christine M. Mauro, Erin M. Annunziato, Anne E. Boustead, Silvia S. Martins
Cannabis use disorder (CUD) treatment prevalence decreased in the US between 2002-2019, yet structural mechanisms for this decrease are poorly understood. We tested associations between cannabis laws becoming effective and self-reported CUD treatment. Restricted-use 2004-2019 National Surveys on Drug Use and Health included people ages 12+ classified as needing CUD treatment (i.e., past-year DSM-5-proxy
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Measuring progress in publishing scholarship in Drug and Alcohol Dependence on race, ethnicity, and health equity in substance use disorder incidence and outcomes Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-02 Katherine M. Keyes, Pia M. Mauro
Abstract not available
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Estimated effectiveness and cost-effectiveness of opioid use disorder treatment under proposed U.S. regulatory relaxations: A model-based analysis Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-01 Gary Qian, Keith Humphreys, Jeremy D. Goldhaber-Fiebert, Margaret L. Brandeau
To assess the effectiveness and cost-effectiveness of buprenorphine and methadone treatment in the U.S. if exemptions expanding coverage for substance use disorder services via telehealth and allowing opioid treatment programs to supply a greater number of take-home doses of medications for opioid use disorder (OUD) continue (Notice of Proposed Rule Making, NPRM). Model-based analysis of buprenorphine
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Morning cannabis use in young adults: Associations with overall levels of use, negative consequences, and cannabis use disorder symptoms across 2.5 years Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-01 Brian H. Calhoun, Katherine Walukevich-Dienst, Scott Graupensperger, Megan E. Patrick, Christine M. Lee
Emerging research suggests morning cannabis use may be associated with using more cannabis and experiencing more cannabis-related consequences. This paper examined whether months when young adults reported morning cannabis use (use between 6:00AM and 12:00PM) were associated with cannabis use frequency, negative cannabis-related consequences, and changes in cannabis use disorder (CUD) symptoms. Participants
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Investigation of the prevalence and factors influencing tobacco and alcohol use among adolescents in Nigeria: A systematic literature review Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-02-01 Mandu S. Ekpenyong, Halimat Jagun, Hope A. Stephen, Aishat T. Bakre, Opeyemi Odejimi, Eula Miller, Mathew Nyashanu, Stella F. Bosun-Arije
The increase in tobacco and alcohol prevalence among Nigerian teenagers necessitates the need to understand the factors influencing use. The aim of this systematic literature review was to synthesis evidence from studies on tobacco and alcohol use among Nigerian adolescents and young adults in order to determine factors influencing tobacco and alcohol use. Six databases MEDLINE, Embase, CINAHL, PsycINFO
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People with a tobacco use disorder exhibit misaligned Bayesian belief updating by falsely attributing non-drug cues as worse predictors of positive outcomes compared to drug cues Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-26 Shivam Kalhan, Philipp Schwartenbeck, Robert Hester, Marta I. Garrido
Adaptive behaviours depend on dynamically updating internal representations of the world based on the ever-changing environmental contingencies. People with a substance use disorder (pSUD) show maladaptive behaviours with high persistence in drug-taking, despite severe negative consequences. We recently proposed a salience misattribution model for addiction (SMMA; Kalhan et al. 2021), arguing that
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Effects of Mint, Menthol, and Tobacco-Flavored E-Cigarettes on Tobacco Withdrawal Symptoms in Adults who Smoke Menthol Cigarettes: A Laboratory Pilot Study Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-25 Mariel S. Bello, Alison R. Schulte, Colin R. Ring, Junhan Cho, Jessica L. Barrington-Trimis, Raina D. Pang, Nancy C. Jao, Suzanne M. Colby, Rachel N. Cassidy, Adam M. Leventhal
Background Menthol cigarette smoking has remained stable or increased in certain groups, despite an overall decline in cigarette smoking rates in the U.S. Understanding whether e-cigarettes alter patterns of menthol cigarette use is critical to informing efforts for reducing the public health burden of menthol cigarette smoking. This 2019-2020 laboratory pilot study evaluated whether self-administration
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Structural indices of brain aging in methamphetamine use disorder Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-23 Johannes Petzold, Jean-Baptiste F. Pochon, Dara G. Ghahremani, Edythe D. London
Background Methamphetamine use is surging globally. It has been linked to premature stroke, Parkinsonism, and dementia, suggesting that it may accelerate brain aging. Methods We performed a retrospective study to determine if structural indices of brain aging were more prevalent prior to old age (26 – 54 years) in individuals with Methamphetamine Use Disorder (MUD), who were in early abstinence (M
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Effects of fentanyl and the adulterant levamisole on the rewarding and locomotor effects of methamphetamine in rats Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-20 Miguel I. Paz-Ramos, Valeria Violante-Soria, Thom Browne, Silvia L. Cruz
Background People who use psychostimulant substances can be exposed to unknown adulterants, such as the synthetic opioid fentanyl (FEN) and the anthelmintic cholinergic agent levamisole (LEV). This work explores the rewarding and locomotor effects of methamphetamine (METH) in combination with FEN or LEV. Methods We used adult male Wistar rats in the conditioned-place preference (CPP) paradigm (conditioning
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Examination of reward processing dysfunctions in the left dorsal striatum and other brain regions among psychiatric inpatients with substance use Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-20 Julia Myerson, Mario Montelongo, Katrina Rufino, Michelle Patriquin, Ramiro Salas, Hyuntaek Oh
Background Substance misuse is a major public health issue and research has established attenuated reward responses to drug cues in those who misuse substances. Yet, little is known about whether the expectation of natural reinforcers engages distinct brain regions in substance misuse. Methods Using functional magnetic resonance imaging (fMRI), we delivered juice at expected and unexpected times to
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Test-retest reliability of DSM-5 substance use symptom checklists used in primary care and mental health care settings Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-24 Kevin A. Hallgren, Theresa E. Matson, Malia Oliver, Xiaoming Wang, Emily C. Williams, Katharine A. Bradley
Introduction Substance use disorders (SUDs) are underdiagnosed in healthcare settings. The Substance Use Symptom Checklist (SUSC) is a practical, patient-report questionnaire that has been used to assess SUD symptoms based on Diagnostic and Statistical Manual of Mental Disorders-5th edition (DSM-5) criteria. This study evaluates the test-retest reliability of SUSCs completed in primary and mental health
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Negative consequences associated with daily alcohol use as a nonlinear function of number of drinks in a daily diary study Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-17 Rebecca J. Evans-Polce, Jennifer L. Maggs, Stephanie T. Lanza, Megan E. Patrick
Introduction Drinking intensity among young adults is associated with greater negative alcohol-related consequences, but often studied using categorical drinking thresholds. This study examined how alcohol-related consequences varied as a continuous function of number of drinks consumed, without imposing thresholds, to identify drink ranges for which risk is greatest. Methods Analyses included daily
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Mobile Medication Adherence Platform for Buprenorphine (MAP4BUP): A Phase I feasibility, usability and efficacy pilot randomized clinical trial Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-22 Sterling M. McPherson, Crystal L. Smith, Luke Hall, André Q. Miguel, Theresa Bowden, Abigail Keever, Alex Schmidt, Katie Olson, Nicole Rodin, Michael G. McDonell, John M. Roll, Jeff LeBrun
Background/aim Poor medication adherence is one of the main barriers to the long-term efficacy of buprenorphine/naloxone (BUP/NAL). The aims of this pilot investigation were to examine if a Bluetooth-enabled pill cap and mobile application is a feasible, usable tool for increasing BUP/NAL adherence among people with an opioid use disorder. Methods This pilot randomized clinical trial (RCT; total n
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Corrigendum to “Examining a brief measure and observed cutoff scores to identify reward and relief drinking profiles: Psychometric properties and pharmacotherapy response” [Drug Alcohol Depend. 232 (2022) 109257] Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-18 Victoria R. Votaw, Karl Mann, Henry R. Kranzler, Corey R. Roos, Helmut Nakovics, Katie Witkiewitz
Abstract not available
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Contingency management is associated with positive changes in attitudes and reductions in cannabis use even after discontinuation of incentives among non-treatment seeking youth Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-20 Megan E. Cooke, Sarah J. Knoll, Joanna M. Streck, Kevin Potter, Erin Lamberth, Natali Rychik, Jodi M. Gilman, A. Eden Evins, Randi M. Schuster
Background It is important to identify interventions that reduce harm in youth not motivated to change their cannabis use. This study evaluated how short-duration contingency management (CM) impacts cannabis use attitudes and behavior after abstinence incentives are discontinued among non-treatment seeking youth. Methods Participants (N=220) were randomized to 4 weeks of abstinence-based CM (CB-Abst;
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A brief measure of non-drug reinforcement: Association with treatment outcomes during initial substance use recovery Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-18 Samuel F. Acuff, Jennifer D. Ellis, Jill A. Rabinowitz, Martin Hochheimer, J. Gregory Hobelmann, Andrew S. Huhn, Justin C. Strickland
Background Translational research demonstrates that drug use is inversely associated with availability and engagement with meaningful non-drug reinforcers. Evaluation of non-drug reinforcement in treatment-receiving clinical populations is limited, likely owing to the time intensive nature of existing measures. This study explores the association of non-drug reinforcers with treatment outcomes using
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Methamphetamine use shortens telomere length in male adults and rats Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-17 Guanyi Lu, Ting Fang, Xinyue Li, XiaoJie Zhang, Hong Li, Ning Wu, Feng Liu, Wei Hao, Qi-Nong Ye, Long Cheng, Jin Li, Fei Li
Background Methamphetamine (MA) use increases the risk of age-related diseases. However, it remains uncertain whether MA use exhibits accelerated biological aging, as indicated by telomere length (TL), a proposed marker of aging. Here we conducted studies in both humans and rats to investigate the association between MA use and TL. Methods We recruited 125 male MA users and 66 healthy controls, aged
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A systematic review of task-sharing interventions for substance use and substance use disorder in low- and middle-income countries Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-17 Asma’u Abba Hassan, Abba M. Ibrahim, Abhijit Nadkarni
Introduction Substance use (SU) and substance use disorders (SUDs) are associated with adverse health and socio-economic consequences. Due to the shortage of specialist healthcare providers, people with SUDs in low- and middle-income countries (LMICs) have limited access to adequate treatment. Task-sharing with non-specialist health workers (NSHWs) has the potential to improve treatment accessibility
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Resting state functional connectivity in dependent cannabis users: The moderating role of cannabis attitudes Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-15 E. Kroon, Y.J. Toenders, L.N. Kuhns, J. Cousijn, F. Filbey
Background The global increase in lenient cannabis policy has been paralleled by reduced harm perception, which has been associated with cannabis use initiation and persistent use. However, it is unclear how cannabis attitudes might affect the brain processes underlying cannabis use. Methods Resting state functional connectivity (RSFC) within and between the executive control network (ECN), salience
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Prediction of adverse events risk in patients with comorbid post-traumatic stress disorder and alcohol use disorder using electronic medical records by deep learning models Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-09 Oshin Miranda, Peihao Fan, Xiguang Qi, Haohan Wang, M.Daniel Brannock, Thomas Kosten, Neal David Ryan, Levent Kirisci, LiRong Wang
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Immigration status-related exclusive e-cigarette use and cannabis use and their dual use disparities associated with mental health disorder symptoms Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-06 David Adzrago, Saanie Sulley, Faustine Williams
Introduction E-cigarette and cannabis use has been linked to various health risks, including respiratory and cardiovascular conditions. Yet, extant knowledge about the risk factors for exclusive and dual use of e-cigarettes and cannabis is limited, especially among immigrants. We examined exclusive e-cigarette and cannabis use and their dual use associated with mental health disorders among immigrants
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Substance use and treatment disparities among Asian Americans, Native Hawaiians, and Pacific Islanders: A systematic review Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-11 Sugy Choi, Sueun Hong, Ohshue S. Gatanaga, Alexander J. Yum, Sahnah Lim, Charles J. Neighbors, Stella S. Yi
Background The increasing relevance of substance use disorder (SUD) within the Asian American, Native Hawaiian, and Pacific Islander (AA&NH/PI) communities, particularly amidst rising anti-Asian hate incidents and the disproportionate health and economic challenges faced by the NH/PI community during the COVID-19 pandemic, underscores the urgency of understanding substance use patterns, treatment disparities
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Mortality risk and causes of death among people who use opioids in a take-home naloxone cohort Drug Alcohol Depen. (IF 4.2) Pub Date : 2024-01-11 Øystein Bruun Ericson, Desiree Eide, Philipp Lobmaier, Thomas Clausen
Background People who use opioids (PWUO) have an excess mortality from a range of causes. The cumulative effect of behavioral, social, and health risk factors complicates the interpretation of the effects of suitable interventions. This study explores mortality causes among a cohort of PWUO in the take-home naloxone (THN) program. Methods This was a prospective cohort study of PWUO who received THN