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The Impact of Excluding Adverse Neonatal Outcomes on the Creation of Gestational Weight Gain Charts Among Women from Low- and Middle-income Countries with Normal and Overweight BMI Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-22 Thais Rangel Bousquet Carrilho, Dongqing Wang, Jennifer A Hutcheon, Molin Wang, Wafaie W Fawzi, Gilberto Kac, members of the GWG Pooling Project Consortium, Manfred Accrombessi, Seth Adu-Afarwuah, João Guilherme Alves, Carla Adriane Leal de Araújo, Shams Arifeen, Rinaldo Artes, Per Ashorn, Ulla Ashorn, Nega Assefa, Omolola Olukemi Ayoola, Fereidoun Azizi, Ahmed Tijani Bawah, Samira Behboudi-Gandevani
Existing gestational weight gain (GWG) charts vary considerably in their choice of exclusion/inclusion criteria, and it is unclear to what extent these criteria create differences in the charts’ percentile values. We aimed to establish the impact of including/excluding pregnancies with adverse neonatal outcomes when constructing GWG charts. This is an individual participant data analysis from 31 studies
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Addressing misinformation about the Dietary Guidelines for Americans Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-22 Janet M de Jesus, Eve E Stoody, Dana M DeSilva, Julia B Quam, Julie E Obbagy, Dennis Anderson-Villaluz, Elizabeth B Rahavi, Meghan E Adler, Tessa A Lasswell, Kara A Beckman
The Dietary Guidelines for Americans (DGA) provides science-based advice on dietary intake to promote health, reduce risk of chronic disease, and meet nutrient needs. It is jointly published by the United States Departments of Health and Human Services and Agriculture (USDA) every 5 y. As chronic diseases continue to rise to pervasive levels, helping the United States population follow the DGA is especially
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Corrigendum to ‘Sugar-sweetened or artificially-sweetened beverage consumption, physical activity, and risk of cardiovascular disease in adults: a prospective cohort study’The American Journal of Clinical Nutrition volume 119 issue 3 (2024) 669-681 Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-21 Lorena S Pacheco, Deirdre K Tobias, Yanping Li, Shilpa N Bhupathiraju, Walter C Willett, David S Ludwig, Cara B Ebbeling, Danielle E Haslam, Jean-Philippe Drouin-Chartier, Frank B Hu, Marta Guasch-Ferré
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Substitution of dietary monounsaturated fatty acids from olive oil for saturated fatty acids from lard increases low-density lipoprotein apolipoprotein B-100 fractional catabolic rate in subjects with dyslipidemia associated with insulin resistance: a randomized controlled trial Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-20 Louis-Charles Desjardins, Francis Brière, André J Tremblay, Maryka Rancourt-Bouchard, Jean-Philippe Drouin-Chartier, Jacques Corbeil, Valéry Lemelin, Amélie Charest, Ernst J Schaefer, Benoît Lamarche, Patrick Couture
The substitution of monounsaturated acids (MUFAs) for saturated fatty acids (SFAs) is recommended for cardiovascular disease prevention but its impact on lipoprotein metabolism in subjects with dyslipidemia associated with insulin resistance (IR) remains largely unknown. This study aimed to evaluate the impact of substituting MUFAs for SFAs on the in vivo kinetics of apolipoprotein (apo)B-containing
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Corrigendum to “Inulin-type fructans and 2’fucosyllactose alter both microbial composition and appear to alleviate stress-induced mood state in a working population compared to placebo (maltodextrin): the EFFICAD Trial, a randomized, controlled trial” [Am J Clin Nutr 118(5) 2023 938-955] Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-19 Peter PJ Jackson, Anisha Wijeyesekera, Claire M Williams, Stephan Theis, Jessica van Harsselaar, Robert A Rastall
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The association between body mass index and metabolite response to a liquid mixed meal challenge: a Mendelian randomization study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-16 David A Hughes, Ruifang Li-Gao, Caroline J Bull, Renée de Mutsert, Frits R Rosendaal, Dennis O Mook-Kanamori, Ko Willems van Dijk, Nicholas J Timpson
Metabolite abundance is a dynamic trait that varies in response to environmental stimuli and phenotypic traits, such as food consumption and body mass index (BMI, kg/m). In this study, we used the Netherlands Epidemiology of Obesity (NEO) study data to identify observational and causal associations between BMI and metabolite response to a liquid meal. A liquid meal challenge was performed, and Nightingale
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Dietary n-3 polyunsaturated fatty acids alter the number, fatty acid profile and coagulatory activity of circulating and platelet-derived extracellular vesicles: a randomized, controlled crossover trial Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-13 Esra Bozbas, Ruihan Zhou, Shin Soyama, Keith Allen-Redpath, Joanne L Mitchell, Helena L Fisk, Philip C Calder, Chris Jones, Jonathan M Gibbins, Roman Fischer, Svenja Hester, Parveen Yaqoob
Extracellular vesicles (EVs) are proposed to play a role in the development of cardiovascular diseases (CVDs) and are considered emerging markers of CVDs. n-3 PUFAs are abundant in oily fish and fish oil and are reported to reduce CVD risk, but there has been little research to date examining the effects of n-3 PUFAs on the generation and function of EVs. We aimed to investigate the effects of fish
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Exploiting meta-analysis of genome-wide interaction with serum 25-hydroxyvitamin D to identify novel genetic loci associated with pulmonary function Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-12 Jungkyun Seo, Nathan C Gaddis, Bonnie K Patchen, Jiayi Xu, R Graham Barr, George O’Connor, Ani W Manichaikul, Sina A Gharib, Josée Dupuis, Kari E North, Patricia A Cassano, Dana B Hancock
Higher 25-hydroxyvitamin D (25(OH)D) concentrations in serum has a positive association with pulmonary function. Investigating genome-wide interactions with 25(OH)D may reveal new biological insights into pulmonary function. We aimed to identify novel genetic variants associated with pulmonary function by accounting for 25(OH)D interactions. We included 211,264 participants from the observational United
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Impact of consuming an environmentally protective diet on micronutrients: a systematic literature review Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-11 Ursula M Leonard, Clarissa L Leydon, Elena Arranz, Mairead E Kiely
A global move toward consumption of diets from sustainable sources is required to protect planetary health. As this dietary transition will result in greater reliance on plant-based protein sources, the impact on micronutrient (MN) intakes and status is unknown. Evaluate the evidence of effects on intakes and status of selected MNs resulting from changes in dietary intakes to reduce environmental impact
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Dietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case–cohort study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-11 Ju-Sheng Zheng, Marinka Steur, Fumiaki Imamura, Heinz Freisling, Laura Johnson, Yvonne T van der Schouw, Tammy YN Tong, Elisabete Weiderpass, Rashmita Bajracharya, Marta Crous-Bou, Christina C Dahm, Alicia K Heath, Daniel B Ibsen, Franziska Jannasch, Verena Katzke, Giovanna Masala, Conchi Moreno-Iribas, Carlotta Sacerdote, Matthias B Schulze, Sabina Sieri, Nicholas J Wareham, John Danesh, Adam S Butterworth
Epidemiological evidence suggests that a potential association between dietary protein intake and cardiovascular disease (CVD) may depend on the protein source, that is, plant- or animal-derived, but past research was limited and inconclusive. To evaluate the association of dietary plant- or animal-derived protein consumption with risk of CVD, and its components ischemic heart disease (IHD) and stroke
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Efficacy and safety of a synbiotic infant formula for the prevention of respiratory and gastrointestinal infections: a randomized controlled trial Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-10 Hugues Piloquet, Bénédicte Vrignaud, Florence Gillaizeau, Odile Capronnier, Kirsten Berding, Julia Günther, Christina Hecht, Christine Regimbart, the GOLF III Study Group
Early life nutrition is crucial for the development of the gut microbiota that, in turn, plays an essential role in the maturation of the immune system and the prevention of infections. The aim of this study was to investigate whether feeding synbiotic infants and follow-on formulas during the first year of life reduces the incidence rate (IR) of infectious diarrhea compared with standard formulas
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Reply to P Phalak et al. Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-08 Adrian Soto-Mota, Yuscely Flores-Jurado, Nicholas G Norwitz, David Feldman, Mark A Pereira, Goodarz Danaei, David S Ludwig
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Very low–carbohydrate and keto diet increases unhealthy cholesterol Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-08 Pradnya Phalak, Abhijit Pratap, Umesh More, Mona Tilak
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Associations of early childhood body mass index trajectories with body composition and cardiometabolic markers at age 10 years: the Ethiopian infant anthropometry and body composition (iABC) birth cohort study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-07 Bikila S Megersa, Gregers S Andersen, Mubarek Abera, Alemseged Abdissa, Beakal Zinab, Rahma Ali, Bitiya Admassu, Elias Kedir, Dorothea Nitsch, Suzanne Filteau, Tsinuel Girma, Daniel Yilma, Jonathan CK Wells, Henrik Friis, Rasmus Wibaek
Variability in body mass index (BMI) (kg/m) trajectories is associated with body composition and cardiometabolic markers in early childhood, but it is unknown how these associations track to later childhood. We aimed to assess associations of BMI trajectories from 0 to 5 y with body composition and cardiometabolic markers at 10 y. In the Ethiopian infant anthropometry and body composition (iABC) birth
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The dynamics in food selection stemming from price awareness and perceived income adequacy: a cross-sectional study using 1-year loyalty card data Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-07 Mikael Fogelholm, Henna Vepsäläinen, Jelena Meinilä, Cameron McRae, Hannu Saarijärvi, Maijaliisa Erkkola, Jaakko Nevalainen
Higher cost of healthy foods may explain unhealthy dietary patterns in lower-income households. Unfortunately, combining food selection and nutrient intake data to price and expenditure is challenging. Food retailer’s customer loyalty card data, linked to nutrient composition database, is a novel method for simultaneous exploration of food purchases, price, and nutrition. We studied the associations
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The impact of heat treatment of bovine milk on gastric emptying and nutrient appearance in peripheral circulation in healthy females: a randomized controlled trial comparing pasteurized and ultra-high temperature milk Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-06 Amber Marie Milan, Matthew PG Barnett, Warren C McNabb, Nicole C Roy, Schynell Coutinho, Caroline L Hoad, Luca Marciani, Samson Nivins, Hayfa Sharif, Stefan Calder, Peng Du, Armen A Gharibans, Greg O’Grady, Karl Fraser, Daniel Bernstein, Sarah M Rosanowski, Pankaja Sharma, Aahana Shrestha, Richard F Mithen
Heat treatments of dairy, including pasteurization and ultra-high temperature (UHT) processing, alter milk macromolecular structures, and ultimately affect digestion. , animal, and human studies show faster nutrient release or circulating appearance after consuming UHT milk (UHT-M) compared with pasteurized milk (PAST-M), with a faster gastric emptying (GE) rate proposed as a possible mechanism. To
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Associations between dietary indices and hearing status among middle-older aged adults – results from the Baltimore Longitudinal Study of Aging Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-05 Yichen Jin, Toshiko Tanaka, Nicholas S Reed, Katherine L Tucker, Luigi Ferrucci, Sameera A Talegawkar
Hearing loss, a public health issue in older populations, is closely related to functional decline. To investigate the longitudinal associations between 4 dietary indices and hearing status. Data from the Baltimore Longitudinal Study of Aging were used and included 882 participants ≥45 y of age. Dietary intake was assessed using a validated food frequency questionnaire, and 4 dietary scores (Mediterranean-Dietary
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Corrigendum to “Functional significance of mild-to-moderate malnutrition” [Am J Clin Nutr 53(2) (1991) 576-577] Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-04 Robert J Karp
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Associations between sodium, potassium, and blood pressure: results from the Hispanic Community Health Study/Study of Latinos, a prospective cohort study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-01 Samuel L Swift, Daniela Sotres-Alvarez, Leopoldo Raij, Sylvia Wassertheil-Smoller, Neil Schneiderman, Maria Llabre, Adina Zeki Al Hazzouri, Tatjana Rundek, Linda Van Horn, Martha Daviglus, Sheila Castaneda, Marston Youngblood, Yasmin Mossavar-Rahmani, Tali Elfassy
Although the subject of numerous studies, the associations between dietary sodium, potassium, and the ratio of dietary sodium to potassium with blood pressure are not clear-cut. In addition, there is a paucity of research on these relationships in prospective cohort studies with representation from diverse Hispanic/Latino adults. To evaluate the associations between dietary intake of sodium, potassium
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Cost-effectiveness of teduglutide in adult patients with short bowel syndrome – a European socioeconomic perspective Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-01 Evelyn Walter, Christopher Dawoud, Elisabeth Hütterer, Anton Stift, Felix Harpain
Short bowel syndrome with intestinal failure (SBS-IF) is a rare but devastating medical condition. An absolute loss of bowel length forces the patients into parenteral support dependency and a variety of medical sequelae, resulting in increased morbidity and mortality. Interdisciplinary treatment may include therapy with the effective but expensive intestinotrophic peptide teduglutide. A time-discrete
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Contribution of Infant Food Pouches and Other Commercial Infant Foods to the Diets of Infants: A Cross-sectional Study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-01 Jillian J Haszard, Anne-Louise M Heath, Ioanna Katiforis, Elizabeth A Fleming, Rachael W Taylor
Although considerable concern has been expressed about the nutritional implications of infant food pouches, how they impact infant diet has not been examined. The objective of this study was to determine the contribution of infant food pouches specifically, and commercial infant foods generally, to nutrient intake from complementary foods in infants. Two multiple-pass 24-h diet recall data were collected
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Birth outcomes in relation to neighborhood food access and individual food insecurity during pregnancy in the Environmental Influences on Child Health Outcomes (ECHO)-wide cohort study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-03-01 Izzuddin M Aris, Pi-I D Lin, Allison J Wu, Dana Dabelea, Barry M Lester, Rosalind J Wright, Margaret R Karagas, Jean M Kerver, Anne L Dunlop, Christine LM Joseph, Carlos A Camargo Jr., Jody M Ganiban, Rebecca J Schmidt, Rita S Strakovsky, Cindy T McEvoy, Alison E Hipwell, Thomas Michael O’Shea, Lacey A McCormack, Luis E Maldonado, Zhongzheng Niu, Assiamira Ferrara, Yeyi Zhu, Rana F Chehab, Eliza W
Limited access to healthy foods, resulting from residence in neighborhoods with low-food access or from household food insecurity, is a public health concern. Contributions of these measures during pregnancy to birth outcomes remain understudied. We examined associations between neighborhood food access and individual food insecurity during pregnancy with birth outcomes. We used data from 53 cohorts
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Effect of 1-year lifestyle intervention with energy-reduced Mediterranean diet and physical activity promotion on the gut metabolome and microbiota: a randomized clinical trial Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-29 Jesús F García-Gavilán, Alessandro Atzeni, Nancy Babio, Liming Liang, Clara Belzer, Jesús Vioque, Dolores Corella, Montserrat Fitó, Josep Vidal, Isabel Moreno-Indias, Laura Torres-Collado, Oscar Coltell, Estefanía Toledo, Clary Clish, Javier Hernando, Huan Yun, Adrián Hernández-Cacho, Sarah Jeanfavre, Courtney Dennis, Ana M. Gómez-Pérez, Maria Angeles Martínez, Miguel Ruiz-Canela, Francisco J. Tinahones
The health benefits of the Mediterranean diet (MedDiet) have been linked to the presence of beneficial gut microbes and related metabolites. However, its impact on the fecal metabolome remains poorly understood. Our goal was to investigate the weight-loss effects of a 1-y lifestyle intervention based on an energy-reduced MedDiet coupled with physical activity (intervention group), compared with an
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Biomarker-assessed total energy intake and its cohort study association with all-cause mortality in postmenopausal females Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-29 Ross L Prentice, Aaron K Aragaki, Cheng Zheng, JoAnn E Manson, Lesley F Tinker, Michele N Ravelli, Yasmin Mossavar-Rahmani, Robert B Wallace, Janet A Tooze, Karen C Johnson, Johanna W Lampe, Marian L Neuhouser, Dale A Schoeller
The association of total energy intake (EI) with all-cause mortality is uncertain as are the dependencies of this association on age and weight change history. To identify an EI biomarker suitable for use in epidemiologic association studies and to study EI associations with total mortality in a Women’s Health Initiative (WHI) cohort of postmenopausal United States females (1993–present). EI biomarkers
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Changes in bile acid subtypes and improvements in lipid metabolism and atherosclerotic cardiovascular disease risk: the Preventing Overweight Using Novel Dietary Strategies (POUNDS Lost) trial Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-28 Yoriko Heianza, Qiaochu Xue, Jennifer Rood, Clary B Clish, George A Bray, Frank M Sacks, Lu Qi
Distinct circulating bile acid (BA) subtypes may play roles in regulating lipid homeostasis and atherosclerosis. We investigated whether changes in circulating BA subtypes induced by weight-loss dietary interventions were associated with improved lipid profiles and atherosclerotic cardiovascular disease (ASCVD) risk estimates. This study included adults with overweight or obesity ( = 536) who participated
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Excluding whole grain-containing foods from the Nova ultraprocessed food category: a cross-sectional analysis of the impact on associations with cardiometabolic risk measures Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-28 Elissa J Price, Mengxi Du, Nicola M McKeown, Marijka J Batterham, Eleanor J Beck
Whole grain (WG) consumption is linked with a reduced risk of chronic disease. However, the recommendations of the Nova classification system tend to contradict this evidence as high WG-containing foods, such as bread and cereals, are considered ultraprocessed, and intake is discouraged. This study aimed to explore associations of cardiometabolic risk measures with ultraprocessed food (UPF) intake
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Taxes to sugar-sweetened beverages: are changes in obesity and diabetes observable? Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-26 Carolina Batis
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Correct information on female leadership at the American Society for Parenteral and Enteral Nutrition Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-26 George P Ayers, Wanda Johnson
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Reply to GP Ayers and W Johnson Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-26 Maria Isabel TD Correia, Bruna R da Silva, Maria Cristina Gonzalez, Nicole Kiss, Eliza Mei Perez Francisco, Carla M Prado
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National taxation on sugar-sweetened beverages and its association with overweight, obesity, and diabetes Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-26 Michele Sassano, Carolina Castagna, Leonardo Villani, Gianluigi Quaranta, Roberta Pastorino, Walter Ricciardi, Stefania Boccia
Consumption of sugar-sweetened beverages (SSBs) has been linked to several adverse health outcomes, thus many countries introduced taxation to reduce it. To summarize national SSB taxation laws and to assess their association with obesity, overweight and diabetes. We conducted a systematic scoping review up to January 2022 on PubMed, Web of Science, Embase, and Google Search to identify taxes on SSBs
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Maternal plasma phospholipid polyunsaturated fatty acids in early pregnancy and thyroid function throughout pregnancy: a longitudinal study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-24 Ling-Jun Li, Ruijin Lu, Shristi Rawal, Anna Birukov, Natalie L Weir, Michael Y Tsai, Jing Wu, Zhen Chen, Cuilin Zhang
Evidence has indicated that polyunsaturated fatty acids (PUFAs)-enriched diet could reduce inflammation because of thyroid autoimmunity in vivo, and therefore, enhance thyroid function. We investigated whether early pregnancy plasma phospholipid PUFAs could benefit maternal thyroid function across pregnancy, which is critical to fetal brain development and growth in pregnancy. Within the National Institute
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Association of body composition indices with cardiovascular outcomes: a nationwide cohort study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-24 Dongyeop Kim, Hyung Jun Kim, Tae-Jin Song
Previous studies regarding BMI (kg/m) and associated cardiovascular outcomes yield inconsistent results. We aimed to investigate the association between body composition and cardiovascular outcomes according to BMI categories in the Korean general population. A total of 2,604,401 participants were enrolled in this nationwide cohort study using the National Health Insurance Service-Health Checkup data
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Can sodium and potassium measured in timed voids be used as reference instruments for validating self-report instruments? Results from a urine calibration study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-23 Laurence S Freedman, Chia-Yih Wang, John Commins, Brian Barrett, Douglas Midthune, Kevin W Dodd, Raymond J Carroll, Victor Kipnis
Sodium and potassium measured in 24-h urine collections are often used as reference measurements to validate self-reported dietary intake instruments. To evaluate whether collection and analysis of a limited number of urine voids at specified times during the day (“timed voids”) can provide alternative reference measurements, and to identify their optimal number and timing. We used data from a urine
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Fasting plasma metabolites reflecting meat consumption and their associations with incident type 2 diabetes in two Swedish cohorts Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-23 Stefania Noerman, Anna Johansson, Lin Shi, Marko Lehtonen, Kati Hanhineva, Ingegerd Johansson, Carl Brunius, Rikard Landberg
Consumption of processed red meat has been associated with increased risk of developing type 2 diabetes (T2D), but challenges in dietary assessment call for objective intake biomarkers. This study aimed to investigate metabolite biomarkers of meat intake and their associations with T2D risk. Fasting plasma samples were collected from a case–control study nested within Västerbotten Intervention Program
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A follow-up from a randomized controlled trial suggests that fish oil in pregnancy may increase the risk of obesity and metabolic syndrome in the offspring—a reason for concern? Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-22 Sjurdur Frodi Olsen
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Fish oil supplementation during pregnancy, anthropometrics, and metabolic health at age ten: A randomized clinical trial Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-22 Rebecca K Vinding, Astrid Sevelsted, David Horner, Nilofar Vahman, Lotte Lauritzen, Casper P Hagen, Bo Chawes, Jakob Stokholm, Klaus Bønnelykke
We previously reported that children of mothers who received fish oil supplementation during pregnancy had higher body mass index [BMI (in kg/m)] at 6 y of age as well as a concomitant increase in fat-, muscle, and bone mass, but no difference in fat percentage. Here, we report follow-up at age 10 y including assessment of metabolic health. This is a follow-up analysis of a randomized clinical trial
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Reply to A Olluri Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-19 Nozomi Sasaki, Laura E Jones, David O Carpenter
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Association Data To Promote Fish And Omega-3 Consumption For Brain Health: Caution Required Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-19 Andi Olluri
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Utilizing the gut microbiome as a biomarker of response to dietary interventions in inflammatory bowel disease: moving toward precision nutrition Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-19 Genelle R Lunken
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New evidence for efficacy of marine-sourced n-3 fatty acids in postoperative patients Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-19 Philip C Calder
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Gut metabolome and microbiota signatures predict response to treatment with exclusive enteral nutrition in a prospective study in children with active Crohn’s disease Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-19 Ben Nichols, Anny Briola, Michael Logan, Jaroslav Havlik, Anna Mascellani, Konstantinos Gkikas, Simon Milling, Umer Zeeshan Ijaz, Christopher Quince, Vaios Svolos, Richard K Russell, Richard Hansen, Konstantinos Gerasimidis
Predicting response to exclusive enteral nutrition (EEN) in active Crohn’s disease (CD) could lead to therapy personalization and pretreatment optimization. This study aimed to explore the ability of pretreatment parameters to predict fecal calprotectin (FCal) levels at EEN completion in a prospective study in children with CD. In children with active CD, clinical parameters, dietary intake, cytokines
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Parenteral n–3 polyunsaturated fatty acids supplementation improves postoperative recovery for patients with Crohn’s disease after bowel resection: a randomized, unblinded controlled clinical trial Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-19 Xiaolong Ge, Huaying Liu, Yan Wu, Wei Liu, Weilin Qi, Linna Ye, Qian Cao, Haifeng Lian, Rongpan Bai, Wei Zhou
The postoperative inflammatory response is associated with postoperative recovery in surgery. n–3 (ω-3) polyunsaturated fatty acids have been reported to lower inflammation. The postoperative role of parenteral n–3 polyunsaturated fatty acids supplementation on outcomes in Crohn’s disease after bowel resection is unclear. We aimed to investigate the effects of postoperative parenteral n–3 polyunsaturated
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Two randomized crossover multicenter studies investigating gastrointestinal symptoms after bread consumption in individuals with noncoeliac wheat sensitivity: do wheat species and fermentation type matter? Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-18 Marlijne CG de Graaf, Emma Timmers, Bo Bonekamp, Gonny van Rooy, Ben JM Witteman, Peter R Shewry, Alison Lovegrove, Antoine HP America, Luud JWJ Gilissen, Daniel Keszthelyi, Fred JPH Brouns, Daisy M.A.E. Jonkers
Many individuals reduce their bread intake because they believe wheat causes their gastrointestinal (GI) symptoms. Different wheat species and processing methods may affect these responses. We investigated the effects of 6 different bread types (prepared from 3 wheat species and 2 fermentation conditions) on GI symptoms in individuals with self-reported noncoeliac wheat sensitivity (NCWS). Two parallel
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Temporal changes in micronutrient intake among United States Adults, NHANES 2003 through 2018: A cross-sectional study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-17 Marjorie R Freedman, Victor L Fulgoni, Harris R Lieberman
Changes in the United States food supply and food choices make examination of temporal changes in micronutrient intake and their effect on meeting nutrient recommendations necessary. This study aimed to examine 15-year trends of the contribution of foods and beverages (FB) and dietary supplements (DSs) to meeting nutrient recommendations among United States adults aged 19 y or older and compare usual
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Early enteral nutrition versus early supplemental parenteral nutrition in patients undergoing major abdominal surgery: a secondary analysis of 2 randomized clinical trials Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-17 Xuejin Gao, Yupeng Zhang, Xin Qi, Yaqin Xiao, Tingting Gao, Gang Jin, Kunhua Wang, Yanbing Zhou, Qiang Chi, Hua Yang, Mengbin Li, Jianchun Yu, Huanlong Qin, Yun Tang, Xiaoting Wu, Guoli Li, Li Zhang, Xinying Wang
The effect of early isoenergetic feeding routes [early enteral nutrition (E-EN) or early supplemental parenteral nutrition (E-SPN)] on the outcome of patients undergoing major abdominal surgery is controversial. The aim of this study was to investigate the impact of early isoenergetic EN compared with early isoenergetic SPN on nosocomial infections in patients undergoing major abdominal surgery. This
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Diagnosing malnutrition—do we really need 6 variables? Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-12 Charlene W Compher
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Predictive validity of the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition indicators to diagnose malnutrition tool in hospitalized adults: a cohort study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-12 Elizabeth Yakes Jimenez, Erin Lamers-Johnson, Julie M Long, George McCabe, Xingya Ma, Lindsay Woodcock, Courtney Bliss, Jenica K Abram, Alison L Steiber
The lack of a widely accepted, broadly validated tool for diagnosing malnutrition in hospitalized patients limits the ability to assess the integral role of nutrition as an input and outcome of health, disease, and treatment. This study aimed to evaluate the predictive validity of the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition (ASPEN) indicators to diagnose
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Higher potassium intake is associated with a lower risk of chronic kidney disease: population-based prospective study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-10 Hyo Jeong Kim, Hee Byung Koh, Ga Young Heo, Hyung Woo Kim, Jung Tak Park, Tae Ik Chang, Tae-Hyun Yoo, Shin-Wook Kang, Kamyar Kalantar-Zadeh, Connie Rhee, Seung Hyeok Han
High-potassium intake is associated with a lower risk of cardiovascular disease. However, the association between potassium intake and the development of chronic kidney disease (CKD) remains unclear. The objective of this study was to investigate whether potassium intake is associated with outcomes of incident CKD. This is a population-based prospective observational cohort study from the UK Biobank
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Cognition after a 4-week high phenylalanine intake in adults with phenylketonuria – a randomized controlled trial Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-09 Roman Trepp, Raphaela Muri, Stephanie Maissen-Abgottspon, Alan G Haynes, Michel Hochuli, Regula Everts
Phenylketonuria (PKU) is an autosomal recessive metabolic disorder characterized by increased phenylalanine (Phe) concentrations in the blood and brain. Despite wide agreement on treatment during childhood, recommendations for adults are still controversial. To assess the impact of a 4-week increase in Phe intake (simulating normal dietary Phe consumption) on cognition, mood, and depression in early-treated
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Workshop summary: building an NHANES for the future Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-06 Anne Frances Johnson, Nancy Lamontagne, Shilpa N Bhupathiraju, Alison GM Brown, Heather A Eicher-Miller, Victor L Fulgoni III, Colin D Rehm, Katherine L Tucker, Catherine E Woteki, Sarah D Ohlhorst
The American Society for Nutrition’s (ASN) Committee on Advocacy and Science Policy (CASP) organized a workshop, “Building a National Health and Nutrition Examination Survey (NHANES) for the Future,” held during NUTRITION 2023, which took place in Boston, MA in July 2023. CASP had already identified an urgent need for increased support and modernization to ensure that a secure future for NHANES is
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Another piece in the complex puzzle of biological responses to (poly)phenols Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-06 Ana Rodriguez-Mateos
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Chronic and postprandial effect of blueberries on cognitive function, alertness, and mood in participants with metabolic syndrome – results from a six-month, double-blind, randomized controlled trial Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-06 Peter J Curtis, Vera van der Velpen, Lindsey Berends, Amy Jennings, Laura Haag, Anne-Marie Minihane, Preeti Chandra, Colin D Kay, Eric B Rimm, Aedín Cassidy
Anthocyanin and blueberry intakes positively associated with cognitive function in population-based studies and cognitive benefits in randomized controlled trials of adults with self-perceived or clinical cognitive dysfunction. To date, adults with metabolic syndrome (MetS) but without cognitive dysfunction are understudied. Cognitive function, mood, alertness, and sleep quality were assessed as secondary
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Protein intake affects erythrocyte glutathione synthesis in healthy adults aged ≥60 years in a repeated-measures trial Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-05 Alyssa Paoletti, Paul B. Pencharz, Mahroukh Rafii, Christopher Tomlinson, Dehan Kong, Libai Xu, Rajavel Elango, Glenda Courtney-Martin
Protein recommendations for older adults are based on nitrogen balance data from young adults. Physiological studies using the indicator amino acid oxidation method suggest they need 30% to 50% more protein than current recommendations. We herein present glutathione (GSH) as a physiological estimate of protein adequacy in older adults. The objective was to measure GSH kinetics in response to varying
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Environmentally protective diets may come with trade-offs for micronutrient adequacy Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-02 Ty Beal
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Temporal gut microbiota variability and association with dietary patterns: From the one-year observational Diet, Cancer, and Health - Next Generations MAX study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-01 Agnetha L Rostgaard-Hansen, Anders Esberg, Johan Dicksved, Torben Hansen, Erik Pelve, Carl Brunius, Jytte Halkjær, Anne Tjønneland, Ingegerd Johansson, Rikard Landberg
Knowledge about the variability of gut microbiota within an individual over time is important to allow meaningful investigations of the gut microbiota in relation to diet and health outcomes in observational studies. Plant-based dietary patterns have been associated with a lower risk of morbidity and mortality and may alter gut microbiota in a favorable direction. To assess the gut microbiota variability
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Phenylketonuria in adults: what do we know? Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-01 Robin Lachmann, Mirjam Langeveld
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Metabolomics of Ramadan fasting and associated risk of chronic diseases Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-01 Rami Al-Jafar, Rui Climaco Pinto, Paul Elliott, Konstantinos K Tsilidis, Abbas Dehghan
The dramatic change in lifestyle associated with Ramadan fasting raises questions about its effect on metabolism and health. Metabolites, as the end product of metabolism, are excellent candidates to be studied in this regard. This study aims to investigate the effect of Ramadan fasting on the metabolic profile and risk of chronic diseases. The London Ramadan study (LORANS) is an observational study
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Untangling the uncertainty in B vitamins for stroke prevention: folic acid fortification, dosage, and their interaction? Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-01 Simin Liu, Peng An
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Dosage exploration of combined B-vitamin supplementation in stroke prevention: a meta-analysis and systematic review Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-02-01 Nan Zhang, ZhongYun Wu, Xinlei Bai, Yun Song, Ping Li, Xinzheng Lu, Yong Huo, Ziyi Zhou
The optimal dosage range for B-vitamin supplementation for stroke prevention has not received sufficient attention. Our aim was to determine the optimal dosage range of a combination of folic acid, vitamin B12, and vitamin B6 supplementation in stroke prevention. We searched PubMed, the Cochrane Central Register of Controlled Trials, and Embase database for randomized controlled trials published between
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The associations of serum vitamin D status and vitamin D supplements use with all-cause dementia, Alzheimer’s disease, and vascular dementia: a UK Biobank based prospective cohort study Am. J. Clin. Nutr. (IF 7.1) Pub Date : 2024-01-29 Li-Ju Chen, Sha Sha, Hannah Stocker, Hermann Brenner, Ben Schöttker
Prior studies on vitamin D and dementia outcomes yielded mixed results and had several important limitations. We aimed to assess the associations of both serum vitamin D status and supplementation with all-cause dementia, Alzheimer’s disease (AD), and vascular dementia (VD) incidence. With a prospective cohort study design, we comprehensively assessed the associations of vitamin D and multivitamin