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External post-mortem examination in virtual reality—scalability of a monocentric application Int. J. Legal Med. (IF 2.1) Pub Date : 2024-04-09 Christina Klus, Katja Krumm, Sindy Jacobi, Marie-Christin Willemer, Charlotte Daub, Dietrich Stoevesandt, Katrin Metzler, Carolin Richter, Lisa-Maria Peter, Steffen Heide, Uwe Schmidt
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An effective method for preparing histological sections of blow fly intra-puparial stages for minimum PMI estimations Int. J. Legal Med. (IF 2.1) Pub Date : 2024-04-09 Daniel Martín-Vega, Thomas J. Simonsen, Martin J. R. Hall
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Prediction model for anabolic androgenic steroid positivity in forensic autopsy cases – a new tool to the autopsy room Int. J. Legal Med. (IF 2.1) Pub Date : 2024-04-08 Paula Vauhkonen, Petteri Oura, Pirkko Kriikku, Katarina Lindroos, Mikko Ilari Mäyränpää
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Development of a protocol for standardized use of a water-soluble contrast agent with polyethylene glycol in post-mortem CT angiography Int. J. Legal Med. (IF 2.1) Pub Date : 2024-04-03 G. M. Bruch, S. Grabherr, C. Bruguier, F. T. Fischer, R. Soto, V. Magnin, P. Genet
Computed tomography angiography (PMCTA) is increasingly used in postmortem cases. Standardized validated protocols permit to compare different PMCTA images and make it more easily to defend a case in court. In addition to the well-known technique by Grabherr et al. (2011) which is using paraffin oil as a carrier substance, water-soluble polyethylene glycol 200 (PEG200) can be used in combination with
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Skin simulants for wound ballistic investigation – an experimental study Int. J. Legal Med. (IF 2.1) Pub Date : 2024-04-03 Victoria K. S. Fischer, Markus A. Rothschild, Beat P. Kneubuehl, Thomas Kamphausen
Gunshot wound analysis is an important part of medicolegal practice, in both autopsies and examinations of living persons. Well-established and studied simulants exist that exhibit both physical and biomechanical properties of soft-tissues and bones. Current research literature on ballistic wounds focuses on the biomechanical properties of skin simulants. In our extensive experimental study, we tested
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Longitudinal visibility of MRI findings in living victims of strangulation Int. J. Legal Med. (IF 2.1) Pub Date : 2024-04-02
Abstract Initial experiences with magnetic resonance imaging (MRI) of living strangulation victims demonstrated additional findings of internal injuries compared to the standard clinical forensic examination. However, existing studies on the use of MRI for this purpose mostly focused on the first 48 h after the incident. The aims of this study were (a) to evaluate the longitudinal visibility of MRI
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Prosecuting cases of abusive head trauma in Switzerland: a descriptive study of the impact of medical documentation and delay of reporting on judicial outcome Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-28 Sarah Held, Jean-Jacques Cheseaux, Jean-François Tolsa, Sarah Depallens
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Dental age assessment and dental scoring systems: combined different statistical methods Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-28 Cristiana Palmela Pereira, Ana Rodrigues, Diana Augusto, Adriana Santos, Valon Nushic, Rui Santos
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Development of a screening system of gene sets for estimating the time of early skeletal muscle injury based on second-generation sequencing technology Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-27 Junyi Shen, Hao Sun, Shidong Zhou, Liangliang Wang, Chaoxiu Dong, Kang Ren, Qiuxiang Du, Jie Cao, Yingyuan Wang, Junhong Sun
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Prioritizing a high posterior probability threshold leading to low error rate over high classification accuracy: the validity of MorphoPASSE software for cranial morphological sex estimation in a contemporary population Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-26 Anežka Pilmann Kotěrová, Frédéric Santos, Šárka Bejdová, Rebeka Rmoutilová, MennattAllah Hassan Attia, Ahmed Habiba, Jana Velemínská, Jaroslav Brůžek
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Immunohistochemical analysis of PDGFR-α for wound age determination Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-23 Wei Zhang, Yuko Ishida, Mizuho Nosaka, Yumi Kuninaka, Akiko Ishigami, Haruki Yasuda, Ayumi Kofuna, Ten Kamata, Utako Goto, Toshikazu Kondo
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New alginate-gelatine method for casting of staining inside firearm barrels Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-23 Christian Schyma, Matthias Berthold
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Evaluation of the usefulness of insertion-null markers in critical skeletal remains Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-20 Christian Haarkötter, María Saiz, Xiomara Gálvez, Diana C. Vinueza-Espinosa, María Isabel Medina-Lozano, Juan Carlos Álvarez, Jose Antonio Lorente
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From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-16 Manrui Li, Yuntian Jin, Yang Xu, Yihan Sun, Ruixuan Yuan, Xiao Zhang, Shengqiu Qu, Meili Lv, Miao Liao, Weibo Liang, Lin Zhang, Xiameng Chen
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Automatic and robust estimation of sex and chronological age from panoramic radiographs using a multi-task deep learning network: a study on a South Korean population Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-12
Abstract Sex and chronological age estimation are crucial in forensic investigations and research on individual identification. Although manual methods for sex and age estimation have been proposed, these processes are labor-intensive, time-consuming, and error-prone. The purpose of this study was to estimate sex and chronological age from panoramic radiographs automatically and robustly using a multi-task
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Advances in body fluid identification: MiRNA markers as powerful tool Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-12 Mohd Hamza, Deeksha Sankhyan, Saurabh Shukla, Preeti Pandey
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Catch me if you can—emission patterns of human bodies in relation to postmortem changes Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-08 Alexandra Schieweck, Nicole Schulz, Jens Amendt, Christoph Birngruber, Franziska Holz
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Identification of a murder caused by brodifacoum poisoning based on clinical examinations and LC-MS/MS results Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-05 Zhonghao Yu, Erjuan Zhao, Qing Shi, Yuhao Yuan, Jinghong Ma, Luwang Zhou, Yijie Duan, Yiwu Zhou
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Evaluation of metal ions and DNA recovery from the surface of fired and unfired brass ammunition to improve STR profiling Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-04 Natalia Czado, Rachel Houston, Sheree Hughes
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Understanding methiopropamine, a new psychoactive substance: an in-depth review on its chemistry, pharmacology and implications to human health Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-01
Abstract Methiopropamine or 1-(thiophen-2-yl)-2-methylaminopropane (MPA) is a thiophene ring-based structural analogue of methamphetamine, first synthesized in 1942 but become popular when it started to be available for purchase on websites selling ‘legal highs’ since 2010. While it is legally controlled in many countries, it remains readily accessible and frequently encountered in recreational settings
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Expanding the scope of methylation-sensitive restriction enzyme (MSRE) PCR for forensic identification of body fluids through the novel use of methylation-dependent restriction enzymes (MDRE) and the combination of autosomal and Y-chromosomal markers Int. J. Legal Med. (IF 2.1) Pub Date : 2024-03-01 Jessica Rothe, Jessica Maria Becker, Maral Charchinezhadamouei, Sophia Mähr, Felizitas Lembeck, Nora Dannemann, Marion Nagy
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Further experiments and remarks regarding the possible formation of blood stains on the Turin Shroud: stains attributed to the nailing of the hands Int. J. Legal Med. (IF 2.1) Pub Date : 2024-02-10 Anna Heger, Lisa König, Alexandra Reckert, Melanie Schröder, Ferhat Kiliç, Farahs Emami, Stefanie Ritz-Timme
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Pediatric motor vehicle crashes injuries: A systematic review for forensic evaluation Int. J. Legal Med. (IF 2.1) Pub Date : 2024-02-10 Elena Giovannini, Simone Santelli, Guido Pelletti, Maria Paola Bonasoni, Angela Cornacchia, Susi Pelotti, Paolo Fais
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Bone age assessment based on different MRI modalities of the proximal humerus epiphysis: the comparisons of T1WI, T2WI, and PDWI Int. J. Legal Med. (IF 2.1) Pub Date : 2024-02-09 Yu-su Jiao, Yilitabier Tuerhong, Cheng-xu Chen, Xin-hua Dai, Ting Lu, Zhao Peng, Zhen-hua Deng, Fei Fan
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Death by accidental intravenous administration of gasoline Int. J. Legal Med. (IF 2.1) Pub Date : 2024-02-09 Pero Bubalo, Marina Nestic, Slavica Martinovic, Marija Bakovic, Davor Mayer, Anita Galic Mihic
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Automated detection of fatal cerebral haemorrhage in postmortem CT data Int. J. Legal Med. (IF 2.1) Pub Date : 2024-02-08 Andrea Zirn, Eva Scheurer, Claudia Lenz
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Methods for the optimal preservation of blow fly intra-puparial forms for morphological analysis in forensic casework Int. J. Legal Med. (IF 2.1) Pub Date : 2024-02-07 Jaime López-García, Mario A. Piña, Brett Clark, Martin J. R. Hall, Daniel Martín-Vega
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Forensic investigation on a combined death by food aspiration and acute escitalopram intoxication occurred to a psychiatric subject in a nursing home Int. J. Legal Med. (IF 2.1) Pub Date : 2024-02-06 P. Zuccarello, G. Carnazza, M. Salerno, M. Esposito, S. Cosentino, A. Giorlandino, F. Sessa, C. Pomara, N. Barbera
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Population affinity estimation using pelvic measurements based on computed tomographic data acquired from Japanese and Western Australian populations Int. J. Legal Med. (IF 2.1) Pub Date : 2024-02-06
Abstract The present study analyzes morphological differences in the pelvis of Japanese and Western Australian individuals and investigates the feasibility of population affinity classification based on computed tomography (CT) data. The Japanese and Western Australian samples comprise CT scans of 207 (103 females; 104 males) and 158 (78 females; 80 males) adult individuals, respectively. Following
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Validating the use of clinical MSCT scans for cranial nonmetric sex estimation in a contemporary Indonesian population Int. J. Legal Med. (IF 2.1) Pub Date : 2024-02-01 Ridhwan Lye, Zuzana Obertová, Nur Amelia Bachtiar, Daniel Franklin
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A 15-year review of lightning deaths in Germany—with a focus on pathognomonic findings Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-30
Abstract Lethal accidents caused by lightning are divided into observed and unobserved events. Pathognomonic or characteristic findings are often overlooked during external postmortem examination. Classical mistakes may be made which may often lead to an incorrect diagnosis. An analysis of 270 fatalities was performed on a historical collection of the Committee for Lightning Conductor Construction
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Radiological age assessment based on clavicle ossification in CT: enhanced accuracy through deep learning Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-30 Philipp Wesp, Balthasar Maria Schachtner, Katharina Jeblick, Johanna Topalis, Marvin Weber, Florian Fischer, Randolph Penning, Jens Ricke, Michael Ingrisch, Bastian Oliver Sabel
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Nails as optimal source of DNA for molecular identification of 5 decomposed bodies recovered from seawater: from Y-ancestry to personal identification Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-29
Abstract Molecular identification of extremely compromised human remains in forensic field is usually performed from DNA typing of bones, which are a difficult sample to work with. Moreover, autosomal STR profiles do not always result in the identification of the donor due to lack of comparisons or non-hit throughout database searching. An attempt to overcome these issues is represented by fingernails
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Age assessment in unaccompanied minors: assessing uniformity of protocols across Europe Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-27 Marco Cummaudo, Zuzana Obertova, Niels Lynnerup, Anja Petaros, Hans de Boer, Eric Baccino, Maryna Steyn, Eugenia Cunha, Ann Ross, Pascal Adalian, Elena Kranioti, Tony Fracasso, Maria Teresa Ferreira, Philippe Lefèvre, Stefano Tambuzzi, Robin Peckitt, Carlo Pietro Campobasso, Oguzhan Ekizoglu, Danilo De Angelis, Cristina Cattaneo
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An overview of the heat-induced changes of the chemical composition of bone from fresh to calcined Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-25
Abstract When bone is exposed to thermal stress, the chemical composition changes. This affects bone tissue regeneration after surgery, and these changes can also aid in reconstructing ante-, peri-, and post-mortem events in forensic investigations and past activities on cremation practices in archaeology. However, to date, no complete overview exists on the chemical composition of both fresh and thermally
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Estimation of ancestry from cranial measurements based on MDCT data acquired in a Japanese and Western Australian population Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-22
Abstract The estimation of ancestry is important not only towards establishing identity but also as a required precursor to facilitating the accurate estimation of other attributes such as sex, age at death, and stature. The present study aims to analyze morphological variation in the crania of Japanese and Western Australian individuals and test predictive models based on machine learning for their
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Epigenetic analyses in forensic medicine: future and challenges Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-20 Maria Carla Gerra, Cristina Dallabona, Rossana Cecchi
The possibility of using epigenetics in forensic investigation has gradually risen over the last few years. Epigenetic changes with their dynamic nature can either be inherited or accumulated throughout a lifetime and be reversible, prompting investigation of their use across various fields. In forensic sciences, multiple applications have been proposed, such as the discrimination of monozygotic twins
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Adult age estimation from the sternum using maximum intensity projection images of CT and data mining in a Chinese population Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-19
Abstract This study aimed to explore and develop data mining models for adult age estimation based on CT reconstruction images from the sternum. Maximum intensity projection (MIP) images of chest CT were retrospectively collected from a modern Chinese population, and data from 2700 patients (1349 males and 1351 females) aged 20 to 70 years were obtained. A staging technique within four indicators was
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Forensic age estimation of the knee by post-mortem DR, CT, and MR imaging: a comparative study Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-19 Apameh Khatam-Lashgari, Mette Lønstrup Harving, Chiara Villa, Niels Lynnerup, Sara Tangmose Larsen
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Morphine concentrations in fatalities after palliative treatment of acute burn injury Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-17 Julian Bickel, Nadine Aboutara, Hilke Jungen, Anne Szewczyk, Alexander Müller, Benjamin Ondruschka, Stefanie Iwersen-Bergmann
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Why identification matters: an explorative study on six cases of family reunification Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-16 Lorenzo Franceschetti, Debora Mazzarelli, Chiara Ragni, Francesca Paltenghi, Andrea Pecoraro, Denise Albani, Roberto Giuffrida, Cecilia Siccardi, Nicolò Polizzi, Paola Di Simone, Annalisa D’Apuzzo, Daniele Mandrioli, Martina Buscemi, Marilisa D’Amico, Ilaria Viarengo, Cristina Cattaneo
The escalating phenomenon of migration, accompanied by a disturbing surge in associated tragedies, has persistently violated internationally protected human rights. Absence of physical evidence, namely the presence of adequately identified corpses, may impede the full enjoyment of human rights and—in some cases—the course of justice as it obstructs the initiation of legal proceedings against individuals
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Cardiac effects of 5F-Cumyl-PEGACLONE Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-12 Nicole Esdar, Evelyn Pawlik, Simon B. Eickhoff, Annika Raupach, Stefanie Ritz-Timme, Felix Mayer
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Technical strategy for monozygotic twin discrimination by single-nucleotide variants Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-10
Abstract Monozygotic (MZ) twins are theoretically genetically identical. Although they are revealed to accumulate mutations after the zygote splits, discriminating between twin genomes remains a formidable challenge in the field of forensic genetics. Single-nucleotide variants (SNVs) are responsible for a substantial portion of genetic variation, thus potentially serving as promising biomarkers for
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Cardiogenic shock in a 28-year-old woman associated with sibutramine use Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-10 Ronghui Wan, Huaxiong Song, Guoqiang Qu, Liang Ren, Xiaowei Zhou, Qishuo Tian, Yunyun Wang, Liang Liu
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Identifying hypothermia death in a mouse model by ATR-FTIR Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-09 Tangdong Chen, Mao Sun, Bowen Li, Yufeng Wang, Juan Zhang, Changwei Xu, Yawen Yu, Lijuan Yuan, Yuanming Wu
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Forensic pilot application of rehydrating solutions on human cadaveric skin: what are the effects on hemorrhagic infiltrates? Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-08 Tambuzzi Stefano, Gentile Guendalina, Raud Lison, Andreola Salvatore, Primavera Riccardo, Zoja Riccardo
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A new, deep learning–based method for the analysis of autopsy kidney samples used to study sex differences in glomerular density and size in a forensic population Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-05 Valérie Vilmont, Nadine Ngatchou, Ghislaine Lioux, Sabrina Kalucki, Wendy Brito, Michel Burnier, Samuel Rotman, Christelle Lardi, Menno Pruijm
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Artificial intelligence in healthcare: why not apply the medico-legal method starting with the Collingridge dilemma? Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-03 Rossana Cecchi, Tudor Mihai Haja, Francesco Calabrò, Iben Fasterholdt, Benjamin S. B. Rasmussen
Technology has greatly influenced and radically changed human life, from communication to creativity and from productivity to entertainment. The authors, starting from considerations concerning the implementation of new technologies with a strong impact on people’s everyday lives, take up Collingridge’s dilemma and relate it to the application of AI in healthcare. Collingridge’s dilemma is an ethical
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Decision tree analysis for age estimation in living individuals: integrating cervical and dental radiographic evaluations within a South African population Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-02 A. Uys, M. Steyn, D. Botha
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Consequences of the lack of clinical forensic medicine in emergency departments Int. J. Legal Med. (IF 2.1) Pub Date : 2024-01-01 Cristina Cattaneo, Stefano Tambuzzi, Stefano De Vecchi, Lidia Maggioni, Giorgio Costantino
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MRI segmentation of tooth tissue in age prediction of sub-adults — a new method for combining data from the 1st, 2nd, and 3rd molars Int. J. Legal Med. (IF 2.1) Pub Date : 2023-12-26 Mai Britt Bjørk, Øyvind Bleka, Sigrid Ingeborg Kvaal, Tomas Sakinis, Frode Alexander Tuvnes, Heidi Beate Eggesbø, Peter Mæhre Lauritzen
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Automated bone age assessment from knee joint by integrating deep learning and MRI-based radiomics Int. J. Legal Med. (IF 2.1) Pub Date : 2023-12-22 Fei Fan, Han Liu, Xinhua Dai, Guangfeng Liu, Junhong Liu, Xiaodong Deng, Zhao Peng, Chang Wang, Kui Zhang, Hu Chen, Chuangao Yin, Mengjun Zhan, Zhenhua Deng
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Severe 25E-NBOH intoxication associated with MDPHP intake: a case report, metabolism study, and literature review Int. J. Legal Med. (IF 2.1) Pub Date : 2023-12-20 Romain Pelletier, Thomas Gicquel, Julien Carvelli, Pierre Balaz, Anne-Laure Pelissier-Alicot, Isabelle Morel, Charline Bottinelli, Caroline Solas, Brendan Le Daré, Nicolas Fabresse
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Skull fractures by glass bottles tested on cadaveric heads Int. J. Legal Med. (IF 2.1) Pub Date : 2023-12-19 Ana I. Lorente, Samuel Maza-Peón, César Hidalgo-García, Carlos López-de-Celis, Jacobo Rodríguez-Sanz, Albert Pérez-Bellmunt, Mario Maza-Frechín
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Female perpetrated sexual assault: a review of attendances to the national sexual assault treatment units in the Republic of Ireland Int. J. Legal Med. (IF 2.1) Pub Date : 2023-12-14
Abstract Background Female perpetrated sexual assault is under-represented in sexual assault research, and indeed possibly an underreported crime. The aim of this study is to address the lack of comprehensive data in relation to female perpetrated sexual assault attendances to the national sexual assault treatment unit network in the Republic of Ireland. Methods This is a cross-sectional study analysing
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Rapid ABO genotyping method using loop-mediated isothermal amplification (LAMP) and real-time PCR Int. J. Legal Med. (IF 2.1) Pub Date : 2023-12-13 Hokwon Choi, Jiwoo Choi, Kyunghyeon Kwak, Yebin Kim, Eunbyeol Kim, Si-Keun Lim
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Artificial intelligence in the practice of forensic medicine: a scoping review Int. J. Legal Med. (IF 2.1) Pub Date : 2023-12-13 Laurent Tournois, Victor Trousset, Didier Hatsch, Tania Delabarde, Bertrand Ludes, Thomas Lefèvre
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Self- and non-self-DNA on hands and sleeve cuffs Int. J. Legal Med. (IF 2.1) Pub Date : 2023-12-06 Léonie Henry, Martin Zieger
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Identification of sudden cardiac death from human blood using ATR-FTIR spectroscopy and machine learning Int. J. Legal Med. (IF 2.1) Pub Date : 2023-12-04 Xiangyan Zhang, Jiao Xiao, Fengqin Yang, Hongke Qu, Chengxin Ye, Sile Chen, Yadong Guo
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Improving the forensic genital examination for trans and gender diverse sexual assault complainants: three case reports Int. J. Legal Med. (IF 2.1) Pub Date : 2023-12-01 Matilda-Jane Oke