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Synergy of de-walled Ganoderma Lucidum spore powder (GLSP) on targeted therapy in advanced non-squamous non-small cell lung cancer with epidermal growth factor receptor (EGFR) mutant: protocol for a randomized, double-blind, placebo-controlled study BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-03-18 Tong-Tong Wu, Yu-Yi Chen, Zi-Chun Yuan, Guo-Wang Yang, Gan-Lin Zhang
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Protective effect of Tao Hong Si Wu Decoction against inflammatory injury caused by intestinal flora disorders in an ischemic stroke mouse model BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-03-18 Lijuan Zhang, Sujun Xue, Changyi Fei, Chao Yu, Jingjing Li, Yumeng Li, Ni Wang, Furui Chu, Lingyu Pan, Xianchun Duan, Daiyin Peng
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The reporting quality of acupuncture-related traumatic adverse events: a systematic review of case studies in Korea BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-03-13 Sung-A Kim, Ji-Su Lee, Tae-Hun Kim, Seunghoon Lee, Jae-Dong Lee, Jung Won Kang
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Clinical study of electroacupuncture on the recovery of gastrointestinal dysfunction after laparoscopic surgery for gastrointestinal cancer - study protocol for a randomized controlled trial BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-03-12 Shuet Ling Chung, Wen Li, Qiuyue Wang, Xiaofeng Qiu, Yuncheng Tang, Sheng Hu, Huangan Wu, Zhu Jin
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Correction: Exploring the antibacterial, antidiabetic, and anticancer potential of Mentha arvensis extract through in‑silico and in‑vitro analysis BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-02-22 Shah Faisal, Muhammad Hamza Tariq, Riaz Ullah, Sania Zafar, Muhammad Rizwan, Nadia bibi, Aishma Khattak, Noora Amir, Abdullah
Correction:BMC Complement Med Ther23, 267 (2023) https://doi.org/10.1186/s12906-023-04072-y Following publication of the original article [1], the authors reported an error in affiliation for author ‘Muhammad Hamza Tariq’. His affiliation was changed from March 2023 and mistakenly shared the old affiliations (‘Department of Chemistry, National Taiwan University, Taipei, Taiwan’ and ‘Institute of Biological
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Anti-bacterial and anti-inflammatory properties of Vernonia arborea accelerate the healing of infected wounds in adult Zebrafish BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-02-19 Lalitha Vaidyanathan, T. Sivaswamy Lokeswari
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Correction: Effect of YuPingFeng granules on clinical symptoms of stable COPD: study protocol for a multicenter, double-blind, and randomized controlled trial BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-02-05 Ruifeng Chen, Yangqing Zhan, Zhengshi Lin, Xiao Wu, Jinchao Zhou, Zifeng Yang, Jinping Zheng
Correction: Complement Med Ther 24, 25 (2024) https://doi.org/10.1186/s12906-023-04271-7 Upon publication of the original article [1], it was noticed that the author “Ruifeng Chen” was mistaken for the co-corresponding author of the article, and the author “Yangqing Zhan” was mistaken for the co-author. The authors “Ruifeng Chen” and “Yangqing Zhan” were both the first authors. The authors “Zifeng
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Effectiveness of Shugan Jieyu capsules for psychiatric symptoms of epilepsy: a systematic review and meta-analysis BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-01-29 Sejin Kim, Yunna Kim, Seung-Hun Cho
The relationship between epilepsy and depression is bidirectional. One condition exacerbates the other. However, there are no current guidelines for treating depression in epilepsy patients. In some cases, seizures worsen when antidepressants (AD) are prescribed or when they are discontinued due to adverse events. The Shugan Jieyu capsule, composed of Acanthopanax senticosus and Hypericum perforatum
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Electro-acupuncture for central obesity: a patient-assessor blinded, randomized sham-controlled clinical trial BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-01-29 Tsz Fung Lam, Zipan Lyu, Xingyao Wu, Yi Ping Wong, Peihua Cao, Emily Yen Wong, Hung Bun Hung, Shiping Zhang, Zhaoxiang Bian, Linda L. D. Zhong
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Mānuka oil based ECMT-154 versus vehicle control for the topical treatment of eczema: study protocol for a randomised controlled trial in community pharmacies in Aotearoa New Zealand BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-01-29 Gabrielle Shortt, Nicholas Shortt, Georgina Bird, Kyley Kerse, Nico Lieffering, Alexander Martin, Allie Eathorne, Bianca Black, Bob Kim, Marius Rademaker, Louise Reiche, Selwyn Te Paa, Suki Harding, Mike Armour, Alex Semprini
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Alleviating effect of lavender (Lavandula angustifolia) and its major components on postherpetic pain: a randomized blinded controlled trial BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-01-24 Jiyeong You, You Kyoung Shin, Geun Hee Seol
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Network pharmacology and in vivo evidence of the pharmacological mechanism of geniposide in the treatment of atherosclerosis BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-01-24 Guiping Ma, Qinqin Dong, Feng Li, Zheng Jin, Jianbin Pi, Wei Wu, Junlong Li
Atherosclerosis (AS) is a fundamental pathological state in various cardiovascular diseases. Geniposide, which is the main active component of Gardenia jasminides, is effective against AS. However, the underlying molecular mechanisms remain unclear. Here, we sought to elucidate them. The targets of AS and geniposide were collected from online public databases. The potential mechanism of Geniposide
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Mindfulness-based interventions to support wellbeing of adults in low socio-economic settings: a realist review BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-01-24 Sarah Foale, Yvonne Botma, Tanya Heyns
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Anti-rheumatic colchicine phytochemical exhibits potent antiviral activities against avian and seasonal Influenza A viruses (IAVs) via targeting different stages of IAV replication cycle BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2024-01-22 Akram Hegazy, Raya Soltane, Ahlam Alasiri, Islam Mostafa, Ahmed M. Metwaly, Ibrahim H. Eissa, Sara H. Mahmoud, Abdou Kamal Allayeh, Noura M. Abo Shama, Ahmed A. Khalil, Ramya S. Barre, Assem Mohamed El-Shazly, Mohamed A. Ali, Luis Martinez-Sobrido, Ahmed Mostafa
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Antimicrobial, antioxidant and cytotoxic activities of the leaf and stem extracts of Carissa bispinosa used for dental health care BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-15 Wanda Shekwa, Tsolanku Sidney Maliehe, Peter Masoko
Carissa bispinosa (L.) Desf. ex Brenan is one of the plants used traditionally to treat oral infections. However, there is limited data validating its therapeutic properties and photochemistry. The aim of this study was to investigate the protective efficacy of the leaf and stem extracts of C. bispinosa against oral infections. The phenolic and tannin contents were measured using Folin-Ciocalteau method
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Proteomic analysis reveals the molecular mechanism of Astragaloside in the treatment of non-small cell lung cancer by inducing apoptosis BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-15 Jiaqi Liu, Yan Sun, Wenjing Chen, Lingling Deng, Mengmeng Chen, Jingcheng Dong
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Artichoke (Cynara scolymus L.) water extract alleviates palmitate-induced insulin resistance in HepG2 hepatocytes via the activation of IRS1/PI3K/AKT/FoxO1 and GSK-3β signaling pathway BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-15 Aihua Deng, Yun Wang, Kerui Huang, Peng Xie, Ping Mo, Fengying Liu, Jun Chen, Kaiyi Chen, Yun Wang, Bing Xiao
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Ammidin ameliorates myocardial hypoxia/reoxygenation injury by inhibiting the ACSL4/AMPK/mTOR-mediated ferroptosis pathway BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-15 Yue Han, Hui Yuan, Fengxiang Li, Yueying Yuan, Xuezhi Zheng, Xudong Zhang, Jian Sun
The aim of the present study was to investigate the therapeutic effect of ammidin on hypoxia/reoxygenation (H/R) injury in primary neonatal rat cardiomyocytes by observing the role of ferroptosis in the process of H/R injury, and to verify its target and regulatory signaling pathways. The network pharmacology analysis was used to predict the biological processes, core targets and related signaling
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Integrated bioinformatics and network pharmacology to explore the therapeutic target and molecular mechanisms of Bailing capsule on polycystic ovary syndrome BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-15 Hao-ru Guan, Bo Li, Ze-hua Zhang, Han-song Wu, Xing-lishang He, Ying-jie Dong, Jie Su, Gui-yuan Lv, Su-hong Chen
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Evaluation of antioxidant, anti-inflammatory, anticancer activities and molecular docking of Moringa oleifera seed oil extract against experimental model of Ehrlich ascites carcinoma in Swiss female albino mice BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-14 Tahany Saleh Aldayel, Heba N. Gad El Hak, Mohamed S. Nafie, Raneem Saad, Heba M. A. Abdelrazek, Omnia E. Kilany
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Effectiveness of Salvadora persica toothbrush and Salvadora persica chewing stick in plaque and gingivitis control: a randomized control trial BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-14 Nurul Fatin Azizan, Nurulhuda Mohd, Nik Madihah Nik Azis, Badiah Baharin
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A comparative analysis of complementary therapies use among patients attending diabetic clinics in Taiwan: 2007 vs. 2023 BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-13 Hsiao-Yun Chang, Yu-Yao Huang, Chin-Jung Chung, Feng-Hsuan Liu
We conducted a comparative study to examine the differences in the use of complementary therapies (CT) among patients who attended diabetic clinics for follow-up treatment between 2007 and 2023 in Taiwan. This study employed a cross-sectional survey design to recruit individuals with diabetes from two regions (northern and southern) of Taiwan. A total of 183 and 307 participants were included in the
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Allopathic Medicine Practitioners’ perspectives on facilitating disclosure of traditional medicine use in Gauteng, South Africa: a qualitative study BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-12 Lindiwe Gumede, Pauline B. Nkosi, Maureen N. Sibiya
Traditional medicine (TM) plays a key role in maintaining health in many societies. Given the requirement for TM disclosure, Allopathic Medicine Practitioners (AMPs) must encourage open communication with patients to persuade those who use TM to disclose. Addressing patient non-disclosure of TM requires this dialogue to be facilitated. We sought to understand and describe how South African AMPs facilitate
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Phytochemical profile and antimicrobial activity of essential oils from two Syzygium species against selected oral pathogens BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-12 Sahar S. Salem, Heba E. Elsayed, Samah Shabana, Mohamed T. Khazaal, Fatma A. Moharram
The genus Syzygium (Myrtaceae) comprises several essential oil-rich species that are utilized traditionally for treating tooth infections and toothache. The current study aimed to extract essential oils (EOs) from the leaves of Syzygium samarangense and Syzygium malaccense cultivated in Egypt for the first time and screen their antimicrobial potential against oral-related pathogens. The intended EOs
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Sweet-type star fruit supplementation controls oxidative stress status and enhances the community walking capacity among elderly Thai BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-11 Jynwara Kaju, Jirakrit Leelarungrayub, Surapol Natakankitkul, James J Laskin
Sweet-type Star fruit (SF) (Averrhoa carambola L.) is seasonal and more available for purchase in many markets in Thailand, when compared to the sour-type. But, its antioxidant activity results and potentially more modified supplement for elderly health during regular exercise in the community are unclear. This study aimed to evaluate the antioxidant activity and physical capacity from supplementation
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Danlou Recipe promotes cholesterol efflux in macrophages RAW264.7 and reverses cholesterol transport in mice with hyperlipidemia induced by P407 BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-08 Wenrun Han, Dandan Zhang, Peng Zhang, Qianqian Tao, Xiaoli Du, Chunquan Yu, Pengzhi Dong, Yan Zhu
Liver X Receptor (LXR) agonists could attenuate the development of atherosclerosis but bring excess lipid accumulation in the liver. Danlou Recipe was believed to be a benefit for improving the lipid profile. Thus, it is unclear whether Danlou Recipe could attenuate hyperlipidemia without excess lipid accumulated in the liver of mice. This study aimed to clarify if Danlou Recipe could alleviate the
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Clinical efficacy of Yukgunja-tang combined with a proton pump inhibitor for refractory gastroesophageal reflux disease: study protocol for randomized, double-blind, double-dummy clinical trial BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-07 Na-Yeon Ha, Jung-Wook Kim, Jinsung Kim
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Correction: Traditional medicine users in a treated chronic disease population: a cross-sectional study in Indonesia BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-06 Ivan Surya Pradipta, Kevin Aprilio, Raden Maya Febriyanti, Yozi Fiedya Ningsih, Mochammad Andhika Aji Pratama, Raden Bayu Indradi, Vesara Ardhe Gatera, Sofa Dewi Alfian, Auliya Iskandarsyah, Rizky Abdulah
Correction: BMC Complement Med Ther 23, 120 (2023) https://doi.org/10.1186/s12906-023-03947-4 We have noticed several errors in the data presentation of our article [1]. These errors do not impact the Results and Discussion section in the article, as the interpretation was made based on the correct information. However, we believe these errors might confuse readers’ interpretation of the study. Hence
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Cancer patients’ behaviors and attitudes toward natural health products BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-06 Audrey Schils, Anne-Sophie Lechon, Sarah Rondeaux, Florence Souard, Jean-Luc Van Laethem, Stephanie Pochet, Veronique Mathieu, Carine De Vriese
Natural health products (NHPs), including vitamins, minerals, and herbal supplements, are the most common complementary and alternative medicine (CAM) among cancer patients. Our survey determined the attitudes and behaviors of cancer patients toward natural complementary therapies that should be considered to implement an integrative approach in the future. Our survey was conducted in four hospitals
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Ethanol extract of Andrographis paniculata alleviates aluminum-induced neurotoxicity and cognitive impairment through regulating the p62-keap1-Nrf2 pathway BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-06 Jianping Ma, Miao Zheng, Xinyue Zhang, Jiaqi Lu, Lili Gu
Alzheimer’s disease (AD) is the most prevalent neurodegenerative and remains incurable. Aluminum is a potent neurotoxin associated with AD. The main pathological features of AD are extracellular amyloid-β protein deposition and intracellular hyperphosphorylated Tau protein. A body of evidence suggest that oxidative stress and autophagy are involved in the pathogenesis of AD. Andrographis paniculata
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Antioxidant and antidiabetic flavonoids from the leaves of Dypsis pembana (H.E.Moore) Beentje & J.Dransf., Arecaceae: in vitro and molecular docking studies BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-05 Mohamed S. Abdelrahim, Afaf M. Abdel-Baky, Soad A.L. Bayoumi, Enaam Y. Backheet
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A model of purchase intention of complementary and alternative medicines: the role of social media influencers’ endorsements BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-05 Gizem Gülpınar, Mehmet Barlas Uzun, Ayesha Iqbal, Claire Anderson, Wajid Syed, Mahmood Basil A. Al-Rawi
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Effect of camel milk on lipid profile among patients with diabetes: a systematic review, meta-analysis, and meta-regression of randomized controlled trials BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-04 Narmin Khalid, Dana N. Abdelrahim, Nivine Hanach, Refat AlKurd, Moien Khan, Lana Mahrous, Hadia Radwan, Farah Naja, Mohamed Madkour, Khaled Obaideen, Husam Khraiwesh, MoezAlIslam Faris
The effects of camel milk (CM) intake on lipid profile among patients with diabetes remain controversial. This systematic review and meta-analysis of randomized controlled trials (RCTs) aimed to calculate the effect size of CM intake on blood lipids among patients with type 1 (T1D) and type 2 (T2D) diabetes. We searched nine databases from inception until December 31, 2022, to identify relevant RCTs
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Ethanol extract of Paridis rhizoma attenuates carrageenan-induced paw swelling in rats by inhibiting the production of inflammatory factors BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-04 Li Xiang, Qinwan Huang, Tao Chen, Qingman He, Huan Yao, Yongxiang Gao
Inflammation has been identified as a key factor contributing to the development of numerous diseases. Several anti-inflammatory drugs have been developed to treat inflammation-related diseases. However, some of such drugs are associated with varying degrees of side effects. Therefore, it is imperative to develop new anti-inflammatory drugs with reducing side effects for the treatment of inflammation-related
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Diosbulbin C, a novel active ingredient in Dioscorea bulbifera L. extract, inhibits lung cancer cell proliferation by inducing G0/G1 phase cell cycle arrest BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-04 Zhiyu Zhu, Yanfen Liu, Jiangping Zeng, Shuyi Ren, Lu Wei, Fei Wang, Xiaoyu Sun, Yufei Huang, Haiyang Jiang, Xinbing Sui, Weiwei Jin, Lijun Jin, Xueni Sun
Despite the critical progress of non-small cell lung cancer (NSCLC) therapeutic approaches, the clinical outcomes remain considerably poor. The requirement of developing novel therapeutic interventions is still urgent. In this study, we showed for the first time that diosbulbin C, a natural diterpene lactone component extracted from traditional Chinese medicine Dioscorea bulbifera L., possesses high
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Comparison of chitosan nanoparticles containing Lippia citriodora essential oil and citral on the induction of apoptosis in A375 melanoma cells BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-01 Abolfazl Karimivaselabadi, Mahmoud Osanloo, Ali Ghanbariasad, Elham Zarenezhad, Hossein Hosseini
Using nanoparticles containing L. citriodora EO and citral has shown potential in treating skin disorders such as melanoma. In this study, GC‒MS was used to analyze the chemical composition of L. citriodora essential oil (EO). The ion gelation method prepared free chitosan nanoparticles and chitosan nanoparticles containing L. citriodora EO and citral. The successful loading of the EO and citral was
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The effects of art therapy on quality of life and psychosomatic symptoms in adults with cancer: a systematic review and meta-analysis BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-01 ShiShuang Zhou, MeiHong Yu, Zhan Zhou, LiWen Wang, WeiWei Liu, Qin Dai
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Network pharmacology-based strategy to investigate the bioactive ingredients and molecular mechanism of Evodia rutaecarpa in colorectal cancer BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-01 Yongqu Lu, Kangdi Dong, Meng Yang, Jun Liu
Evodia rutaecarpa, a traditional herbal drug, is widely used as an analgesic and antiemetic. Many studies have confirmed that Evodia rutaecarpa has an anticancer effect. Here, our study explored the bioactive ingredients in Evodia rutaecarpa acting on colorectal cancer (CRC) by utilizing network pharmacology. We clarified the effective ingredients and corresponding targets of Evodia rutaecarpa. CRC-related
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Knowledge, attitude, and perceptions of healthcare professionals towards complementary and alternative medicine: a cross-sectional survey from twin cities of Pakistan BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-12-01 Azhar Hussain Tahir, Maria Tanveer, Gul Shahnaz, Muhammad Saqlain, Shagufta Ayub, Ali Ahmed
The growing popularity and use of complementary and alternative medicine (CAM) products among the general public worldwide has been well documented. This study aimed to investigate the knowledge, attitude, and perceptions (KAP) of Pakistani healthcare professionals (HCP) toward CAM and to document their views on integrating CAM education with the curriculum of undergraduate health science programs
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Integrated investigation and discovery of therapeutic targets for 3-hydroxybakuchiol against diabetes based on molecular docking studies and cell experiments BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-29 Min Liu, Xinyu Wang, Junsong Yang, Dan Qin
Diabetes mellitus is a prevalent endocrine condition. We aimed to investigate the anti-diabetic effects of 3-hydroxybakuchiol (HYD) by exploring its potential targets and molecular mechanisms through bioinformatics analysis and cell experiments. We performed an extensive search and screening of HYD and its potential targets for diabetes mellitus across various databases. Enrichment analyses were conducted
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Prevention of STAT3-related pathway in SK-N-SH cells by natural product astaxanthin BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-29 Shao-Qian Sun, Feng-Xiang Du, Li-Hua Zhang, Hao-Shi, Fu-Ying Gu, Yu-Lin Deng, Yi-Zhi Ji
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Prevalence and correlates of multimorbidity among patients attending AYUSH primary care settings in Delhi-National Capital Region, India BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-29 Roja Varanasi, Abhinav Sinha, Debadatta Nayak, Raj K. Manchanda, Rajiv Janardhanan, Simran Tandon, Sanghamitra Pati
India has a multifaceted healthcare system and recognizes complementary and alternative systems of medicine (AYUSH) that cater to the healthcare needs of people. Multimorbidity requires frequent visits to physicians and long-term use of medications, due to which people tend to prefer AYUSH systems as they provide holistic patient-centered treatment. Hence, we aimed to estimate the prevalence of multimorbidity
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Comparison effects of Ferula gummosa essential oil and Beta-pinene Alginate nanoparticles on human melanoma and breast cancer cells proliferation and apoptotic index in short term normobaric hyperoxic model BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-28 Mahmoud Osanloo, Somayyeh Pishamad, Ali ghanbariasad, Elham Zarenezhad, Media Alipanah, Hiva Alipanah
Breast cancer is the most common cancer among women, and melanoma is the most dreadful type of skin cancer. Due to the side effects of chemotherapy drugs, the development of new herbal nano-medicines has been considered. This study first investigated the chemical composition of Ferula gummosa essential oil using GC-MS analysis; β-pinene, with 61.57%, was the major compound. Next, alginate nanoparticles
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ITRAQ-based proteomics analysis of human ectopic endometrial stromal cells treated by Maqian essential oil BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-27 Liu-yang Zhang, Ting-ting Huang, Li-ping Li, Dan-ping Liu, Yong Luo, Wan Lu, Ning Huang, Peng-peng Ma, Yan-qiu Liu, Ping Zhang, Bi-cheng Yang
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Correction: Associations between demographics and clinical ideology, beliefs, and practice patterns: a secondary analysis of a survey of randomly sampled United States chiropractors BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-25 Zachary A. Cupler, Jordan A. Gliedt, Stephen M. Perle, Aaron A. Puhl, Michael J. Schneider
Correction: BMC Complement Med Ther 23, 404 (2023) https://doi.org/10.1186/s12906-023-04225-z Following publication of the original article [1], the authors identified an error in Fig. 2 caption. The legend/key are missing. The correct Figure 2 caption is given below. The original article has been corrected. Cupler ZA, Gliedt JA, Perle SM, et al. Associations between demographics and clinical ideology
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Effect of hand reflexology in ameliorating anxiety, pain, and fatigue among patients undergoing coronary angiography BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-24 Eman Abdeen Ali, Wafaa Hassan Ali Awad, Mahmoud Abdelwahab Khedr, Emad Abd El Gawad Ali Rabie
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Shaoyao decoction alleviates TNBS-induced ulcerative colitis by decreasing inflammation and balancing the homeostasis of Th17/Treg cells BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-24 Dongsheng Wu, Yu Zhang, Bo Zou, Yi Lu, Hui Cao
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Gallic acid rescues uranyl acetate induced-hepatic dysfunction in rats by its antioxidant and cytoprotective potentials BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-22 Ibtisam M. H. Elmileegy, Hanan S. A. Waly, Alshaimaa A. I. Alghriany, Nasser S. Abou Khalil, Sara M. M. Mahmoud, Eman A. Negm
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A real-world study and network pharmacology analysis of EGFR-TKIs combined with ZLJT to delay drug resistance in advanced lung adenocarcinoma BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-21 Xue Han, Lan Liang, Chenming He, Qinyou Ren, Jialin Su, Liang Cao, Jin Zheng
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Chemo- and bio-informatics insight into anti-cholinesterase potentials of berries and leaves of Myrtus communis L., Myrtaceae: an in vitro/in silico study BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-21 Baydaa Abed Hussein, Isaac Karimi, Namdar Yousofvand
Myrtus communis L. (MC) has been used in Mesopotamian medicine. Here, the cholinesterase (ChE) inhibitory potential of its methyl alcohol extracts has been investigated and computationally dissected. The ChE inhibition has been measured based on usual Ellman’s colorimetric method compared to a canonical ChE inhibitor, eserine. Through a deep text mining, the structures of phytocompounds (= ligands)
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Integrated network pharmacology and experimental validation to explore the potential pharmacological mechanism of Qihuang Granule and its main ingredients in regulating ferroptosis in AMD BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-21 Lu Wang, Canyang Zhang, Long Pang, Yan Wang
Qihuang Granule (QHG) is a traditional prescription that has exhibited potential in safeguarding against age-related maculopathy (AMD). Salvia miltiorrhiza (SM) and Fructus lycii (FL) are the main components of QHG. Ferroptosis, a newly discovered, iron-dependent, regulated cell death pathway, have been implicated in the pathogenesis of AMD. This study delves into the intricate mechanism by which SM/FL
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Tracking the effect of roasting and fermentation on the metabolites of licorice root (Glycyrrhiza glabra L.) using UPLC-MS analysis combined with multivariate statistical analysis BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-20 Sarah S. Takla, Eman Shawky, Yasmin A. Mahgoub, Reham S. Darwish
Roasting, honey-roasting and fermentation are the most common pre-processing procedures of licorice roots. They were shown to noticeably change the composition of extracts. In this work, the common alterations in licorice secondary metabolites by processing were interpreted. Comprehensive metabolic profiling of different studied samples was undergone. UPLC-QqQ-MS/MS analysis coupled to various chemometric
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Effects of pulmonary-based Qigong exercise in stable patients with chronic obstructive pulmonary disease: a randomized controlled trial BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-20 Linhong Jiang, Peijun Li, Jiacheng Shi, Yidie Bao, Zhenwei Wang, Weibing Wu, Xiaodan Liu
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Correction: Astragalus polysaccharide restores insulin secretion impaired by lipopolysaccharides through the protein kinase B/mammalian target of rapamycin/glucose transporter 2 pathway BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-20 Xiaodan Ren, Ying Dai, Mengya Shan, Jing Zheng, Zhongyi Zhang, Tao Shen
Correction: BMC Complement Med Ther 23, 358 (2023) https://doi.org/10.1186/s12906-023-04188-1 Following publication of the original article [1], the authors identified two errors that need to be corrected. Error Description: In Additional file 1, Supplemental Figure 1 was incorrectly presented as Fig. 5A western blot experimental pictures. In Additional file 1, Supplemental Figure 2 was incorrectly
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Brazilian green propolis prevent Alzheimer’s disease-like cognitive impairment induced by amyloid beta in mice BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-17 Takashi Ito, Tomomi Degawa, Nobuaki Okumura
The increasing incidence of cognitive impairment has become a health problem in the aging society. Owing to its antioxidant and anti-inflammatory properties, Brazilian green propolis—derived from Baccharis dracunculifolia—is anticipated to possess anticognitive properties. However, the preventive effect of Brazilian green propolis on cognitive impairment remains unexplained. This study aimed to investigate
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Prediction and validation of common targets in atherosclerosis and non-small cell lung cancer influenced by atorvastatin BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-17 Yu-qian Li, Lu-yao Li, Xue Yang, Qi-qi Lei, Liu-yan Xiang, Yuan-ru Wang, Si-meng Gu, Ya-jun Cao, Yan Pan, Lu Tie, Xue-jun Li
Cardiovascular disease and cancer are the main causes of morbidity and mortality worldwide. Studies have shown that these two diseases may have some common risk factors. Atorvastatin is mainly used for the treatment of atherosclerosis in clinic. A large number of studies show that atorvastatin may produce anti-tumor activities. This study aimed to predict the common targets of atorvastatin against
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Bei Mu Gua Lou San facilitates mucus expectoration by increasing surface area and hydration levels of airway mucus in an air-liquid-interface cell culture model of the respiratory epithelium BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-17 Silvia Groiss, Ina Somvilla, Christine Daxböck, Manuela Stückler, Elisabeth Pritz, Dagmar Brislinger
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Combinative effects of akarkara root-derived metabolites on anti-inflammatory and anti-alzheimer key enzymes: integrating bioassay-guided fractionation, GC-MS analysis, and in silico studies BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-17 Rana M. Ibrahim, Passent M. Abdel-Baki, Ghada F. Elmasry, Ahmed A. El-Rashedy, Nariman E. Mahdy
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Effect of Uncaria tomentosa aqueous extract on the response to palmitate-induced lipotoxicity in cultured skeletal muscle cells BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-15 Bruna Leticia de Freitas-Marchi, Jeniffer Farias dos Santos, Gustavo Roncoli Reigado, Myrian Thiago Pruschinski Fernandes, Felipe Santiago Chambergo Alcalde, Carla Roberta de Oliveira Carvalho, Viviane Abreu Nunes
Type 2 diabetes mellitus (T2DM) is frequently associated with dyslipidemia, which corresponds to the increase in the triglycerides and fatty acid concentrations in tissues, such as the skeletal muscle. Also, T2DM molecular mechanism involves increasing in reactive oxygen species (ROS) production and oxidative stress. The use of herbal medicines such as Uncaria tomentosa (Ut) has been proposed as an
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Explore the active ingredients and potential mechanisms of JianPi QingRe HuaYu Methods in the treatment of gastric inflammation-cancer transformation by network pharmacology and experimental validation BMC Complement. Altern. Med. (IF 4.782) Pub Date : 2023-11-14 Kechao Nie, Zhihua Zheng, Xiushen Li, Yonglong Chang, FengBin Liu, Xiaoyu Wang
JianPi QingRe HuaYu Methods (JQH) have been long used to treat chronic atrophic gastritis (CAG) and precancerous lesions of gastric cancer (PLGC). However, whether JQH can inhibit the transformation of gastritis to gastric cancer (GC) remains unclear. Herein, we first retrieved the active ingredients and targets of JQH from the TCMSP database and the targets related to the gastric inflammation-cancer