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Atrial fibrillation and preexisting cognitive impairment in ischemic stroke patients: Dijon Stroke Registry Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-04-15 Thibaut Pommier, Gauthier Duloquin, Valentin Pinguet, Pierre-Olivier Comby, Charles Guenancia, Yannick Béjot
Atrial Fibrillation (AF) is a common cause of ischemic stroke (IS), and is associated with cognitive impairment in the general population. We aimed to compare the prevalence of preexisting cognitive impairment between IS patients with and without AF, and to assess whether prior brain damage could contribute to the observed differences. Patients with acute IS were prospectively identified from the population-based
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Factors associated with loneliness among individuals aged 80 years and over: Findings derived from the nationally representative "Old Age in Germany (D80+)" study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-04-10 André Hajek, Razak M. Gyasi, Hans-Helmut König
To clarify the factors associated with loneliness in individuals aged 80 years and older in Germany (also stratified by sex). Data from the nationally representative “Old Age in Germany (D80+)” were employed. The analytic sample equaled 10,031 individuals. The D80+ study included community-dwelling and institutionalized individuals ≥ 80 years in Germany. Multiple linear regressions were used (with
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Prevalence and factors associated with sarcopenia among Brazilian older adults: An exploratory network analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-04-06 Maura Fernandes Franco, Daniel Eduardo da Cunha Leme, Ibsen Bellini Coimbra, Arlete Maria Valente Coimbra
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The grip on healthspan: Handgrip strength as a vital sign of aging Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-04-04 Liang-Kung Chen
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Causal association of monocytes with chronic kidney disease and the mediation role of frailty: A study integrating large-scale two-sample Mendelian randomization and single-cell analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-04-03 Cong Zhang, Jielian Deng, Kangjie Li, Guichuan Lai, Hui Liu, Yuan Zhang, Haijiao Zeng, Wenlong Li, Xiaoni Zhong, Yao Wang, Biao Xie
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The role of olfactory dysfunction in mild cognitive impairment and Alzheimer's disease: A meta-analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-04-02 Jaime Bouhaben, Alice Helena Delgado-Lima, María Luisa Delgado-Losada
This comprehensive meta-analysis investigates the association between olfactory deficits in mild cognitive impairment (MCI) and Alzheimer's disease (AD). A thorough search across databases identified articles analyzing olfactory status in MCI or AD patients. Methodological quality assessment followed PRISMA guidelines. Hedges' g effect size statistic computed standard mean differences and 95% confidence
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Dynapenic abdominal obesity and incident functional disability: Results from a nationwide longitudinal study of middle-aged and older adults in China Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-04-02 Sifan Qian, Qiuqing Wen, Tiansheng Huang, Jing Chen, Xiaobin Feng
There is little epidemiological evidence on the relationship of dynapenic abdominal obesity (DAO) and the development of functional disability, particularly in Asian populations. We aimed to investigate the association of DAO with new-onset functional disability in Chinese adults. A total of 7881 participants aged ≥45 years from China Health and Retirement Longitudinal Study (CHARLS) in 2011 and 2015
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Health-related quality of life during the COVID-19 pandemic and beyond Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-30 André Hajek, Hans-Helmut König
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miR-743b-3p promotes hepatic lipogenesis via branched-chain amino acids (BCAA) metabolism by targeting PPM1K in aged mice Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-26 Ting Lu, Ying Zheng, Xiaoling Chen, Zhiyong Lin, Chaoqi Liu, Chengfu Yuan
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Non-steroidal anti-inflammatory drugs, renin-angiotensin system blockade or diuretics and risk of acute kidney injury: A case-crossover study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-26 Shao-En Weng, Wan-Tseng Hsu, Fei-Yuan Hsiao, Chii-Ming Lee
Aging-related physiological changes, such as decline in renal function, not only exacerbates pre-existing comorbidities but also escalate the susceptibility to adverse events. Previous studies have shown that non-steroidal anti-inflammatory drugs (NSAIDs) are associated with an increased risk of acute kidney injury (AKI), and the concomitant use of renin-angiotensin system blockade or diuretics may
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Short-term dynamics of loneliness and depressive symptoms: Gender differences in older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-25 Hannes Mayerl, Anna Schultz, Wolfgang Freidl, Erwin Stolz
Previous research examining the relationship between loneliness and depressive symptoms often treated these constructs as static traits rather than dynamic states. The current study focused on the short-term, prospective link between loneliness and depressive symptoms, while also analyzing potential gender differences. We modeled panel data from seven bi-weekly assessments gathered in the FRequent
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Effects of 12 weeks of inspiratory muscle training and whole body vibration on the inflammatory profile, BDNF and muscular system in pre-frail elderly women: A randomized controlled trial Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-24 Helga Cecília Muniz de Souza, Maíra Florentino Pessoa, Rafaela dos Santos Clemente, Alanna Vasconcelos da Silva, Pablo Ramon Gualberto Cardoso, Juliana Fernandes, Arméle Dornelas de Andrade
to investigate the effects of the whole body vibration (WBV) and inspiratory muscle training (IMT) on the inflammatory profile and in muscle mass and strength in pre-frail older women. this study was a randomized double-blind trial. Forty two older women aged 60–80 years were randomly allocated to IMT + WBV (G1), IMTsham + WBV (G2) or Sham groups (G3). During 12 weeks G1 received both trainings, whereas
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Body mass index and multimorbidity risk: A systematic review and dose-response meta-analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-24 Jun Shan, Rulan Yin, Sirirat Panuthai
To verify the dose-response relationship between body mass index (BMI) and multimorbidity risk. PubMed, CINAHL, and Embase were systematically studied until January 25, 2023. Original articles on BMI and multimorbidity risk were included. Random effects model and dose-response meta-analysis were used to estimate the pooled odds ratio (OR) with 95 % confidence interval (CI). Subgroup analysis was performed
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Incidence of fragility hip fracture across the Asia-pacific region: A systematic review Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-21 Lloyd LY Chan, YY Ho, Morag E Taylor, Catherine Mcveigh, Sonya Jung, Elizabeth Armstrong, Jacqueline CT Close, Lara A Harvey
This systematic review aimed to update fragility hip fracture incidences in the Asia Pacific, and compare rates between countries/regions. A systematic search was conducted in four electronic databases. Studies reporting data between 2010 and 2023 on the geographical incidences of hip fractures in individuals aged ≥50 were included. Exclusion criteria were studies reporting solely on high-trauma, atypical
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Unveiling the muscle-brain axis: A bidirectional mendelian randomization study investigating the causal relationship between sarcopenia-related traits and brain aging Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-21 Zefang Li, Xueqiang Wu, Zhaojun Yan, Yiping Cui, Yueling Liu, Song Cui, Yining Wang, Tianyu Liu
Observational studies suggest an association between sarcopenia-related traits and brain aging, but whether this association reflects a causal relationship remains unclear. This study aims to employ Mendelian randomization (MR) methods to investigate the causal impact of sarcopenia-related traits on brain aging. This study presents a comprehensive analysis of genome-wide association study (GWAS) summary
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APOE and Alzheimer's disease: Pathologic clues from transgenic Drosophila melanogaster Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-20 Mohammad Haddadi, Mehrnaz Haghi, Niloofar Rezaei, Zahra Kiani, Taha Akkülah, Arzu Celik
Alzheimer's disease (AD) is one of the most common forms of neurodegenerative diseases. Apolipoprotein E4 (ApoE4) is the main genetic risk factor in the development of late-onset AD. However, the exact mechanism underlying ApoE4-mediated neurodegeneration remains unclear. We utilized to examine the neurotoxic effects of various human APOE isoforms when expressed specifically in glial and neural cells
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Prevalence of social frailty and risk factors among community-dwelling older adults: A systematic review and meta-analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-16 Bingyun Jia, Zhizhong Wang, Tao Zhang, Xilin Yue, Senhao Zhang
Older people are more vulnerable to social frailty due to age, physical condition and socio-economic status. Since social frailty can lead to adverse health outcomes, it is essential to understand the current state of social frailty among community-dwelling older adults. To consolidate existing evidence for rates of social frailty and risk factors. Two researchers independently selected studies, extracted
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Achieving consensus on assessing health-related quality of life (HRQoL) in people with cognitive impairments (CI)[sbnd]a Delphi study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-16 A. Feißel, M. Berwig, L. Boyer, T. Bratan, C. Schlüfter, J. Loss, C. Apfelbacher
The prevalence of impairments of cognitive functions is expected to increase. Enhancing the QoL of those affected is important. HRQoL in people with CI can be assessed by self-report, proxy-report or observation but there is uncertainty how to best assess HRQoL in people with CI, and which assessment method is most appropriate. Therefore the aim of our study was to use Delphi methodology in order to
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Dementia in Taiwan Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-16 Kelly Cotton, Joe Verghese
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Increased trend in dementia incidence within a Taiwanese National Cohort: What have we learned? What can we do? Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-16 Davide Angioni, Pierre-Jean Ousset, Bruno Vellas
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A major step towards utilization of administrative data in the field of dementia Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-15 Shinya Ishii
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Functional limitation among middle age and older adults: Exploring cross-national gender disparities Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-14 Shane D. Burns, Jennifer A. Ailshire, Eileen M. Crimmins
Functional limitations are prevalent among aging demographics, especially women. Structural and health factors, which vary worldwide, influence rates of functional limitations. Yet, gender disparities in functional limitation remain unclear in a global context. We use 2018 data from the Health and Retirement Study (HRS) international family of studies with respondents ages 50–64 and ( = 87,479) and
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Association of depressive symptoms with cardiovascular events and plasma BNP: A prospective cohort study of the elderly Chinese population Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-12 Xiaoxu Wang, Jianming Shi, Xiaoyan Jiang, Xiaofeng Wang
To estimate the prevalence of depressive symptoms and to evaluate the associations of mild and significant depressive symptoms with cardiovascular events and plasma BNP levels (which are surrogate endpoints for cardiovascular events) among older adults in a population-based study. A population-based prospective study of 1,432 elderly people (aged 70–84 years and without cardiovascular disease) was
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Investigating balance-related gait patterns and their relationship with maximum torques generated by the hamstrings and quadriceps in older adults - Results from the Baltimore longitudinal study of aging Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-12 Seung-uk Ko, Gerald J Jerome, Eleanor M. Simonsick, Luigi Ferrucci
Balance-related gait patterns in older adults can be objectively discerned through the examination of gait parameters, maximum leg torques, and their interconnections. To investigate the correlation between leg muscle strength and balance during gait concerning functional performance in healthy older adults. Participants included 117 adults aged 60-95 years were recruited from the Baltimore Longitudinal
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Socially Assistive Robots for patients with Alzheimer's Disease: A scoping review Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-12 Vania Karami, Mark J. Yaffe, Genevieve Gore, AJung Moon, Samira Abbasgholizadeh Rahimi
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Joint trajectories of physical frailty and social frailty and associations with adverse outcomes: A prospective cohort study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-05 Qinqin Liu, Yuli Huang, Shuai Gao, Binlin Wang, Yanyan Li, Huaxin Si, Wendie Zhou, Jiaqi Yu, Hejing Chen, Cuili Wang
We examined joint trajectories of physical frailty and social frailty as well as their associations with adverse outcomes. We conducted a prospective cohort study by using five waves of national data from China Health and Retirement Longitudinal Study (CHARLS 2011–2020), involving 4531 participants aged ≥60 years. We identified 4-year trajectories at three examinations from 2011 to 2015 using parallel
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The Social and Cognitive Online Training (SCOT) project: A digital randomized controlled trial to promote socio-cognitive well-being in older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-05 Giulia Funghi, Claudia Meli, Arianna Cavagna, Lisa Bisoffi, Francesca Zappini, Costanza Papagno, Alessandra Dodich
Effective prevention programs targeting risk factors for cognitive decline in the elderly are recommended given the progressive increase in the aging of the general population. The Social and Cognitive Online Training (SCOT) project is a randomized, controlled, parallel clinical trial designed to prevent the age-related decline in executive and social functions. The study included 60 cognitively healthy
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Social engagement and cognitive impairment among nursing home residents: The role of sensory impairment Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-05 Shu Xu, William M. Jesdale, Catherine E. Dubé, Natalia N. Nielsen, Emily A. McPhillips, Kate L. Lapane
Using US national nursing home data, this cross-sectional study sought to evaluate 1) the association between lack of social engagement and level of cognitive impairment; and 2) the extent to which this association differs by hearing and visual impairment. Our sample included 793,846 nursing home residents aged ≥ 50 years. The Index of Social Engagement was categorized as none/lower (0, 1, 2) or higher
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Longitudinal relationship between grip strength and cognitive function in a European population older than 50 years: A cross-lagged panel model Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-05 Man Cui, Juan Wang, Miao Deng, Hailan Meng, Yanshuai Fan, Chaoyue Ku, Ruizhe Wang, Binbin Wu, Man Dai, Zhiguang Ping
The aim of this study was to investigate the dynamic longitudinal relationship between grip strength and cognitive function. 6175 participants aged ≥50 years were included in the study using three waves of follow-up data from the Survey of Health, Ageing, and Retirement in Europe in 2015 (T1), 2017 (T2) and 2019 (T3). Cognitive function was assessed using numeracy, verbal fluency, immediate recall
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Cognitively high-performing oldest old individuals are physically active and have strong motor skills–A study of the Danish 1905 and 1915 birth cohorts Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-04 Maja Hermansen, Marianne Nygaard, Qihua Tan, Bernard Jeune, Maria Semkovska, Kaare Christensen, Mikael Thinggaard, Jonas Mengel-From
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Frailty and brain changes in older adults without cognitive impairment: A scoping review Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-04 Gabriela Cabett Cipolli, Isadora Cristina Ribeiro, Clarissa Lin Yasuda, Márcio Luiz Figueredo Balthazar, André Fattori, Mônica Sanches Yassuda
Little is known about changes in the brain associated with frailty, in particular, which brain areas could be related to frailty in older people without cognitive impairment. This scoping review mapped evidence on functional and/or structural brain changes in frail older adults without cognitive impairment. The methodology proposed by the JBI® was used in this study. The search in PubMed, PubMed PMC
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The influence of intergenerational support on cognitive functioning among middle-aged Chinese: Moderation by personal income Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-04 Ping Wang, Chunhai Tao
To analyze the effects of personal income on the relationship between intergenerational support (IS) and cognitive functioning. Data were obtained from four waves of nationally representative surveys of the 2011–2018 China Health and Retirement Longitudinal Study (CHARLS), involving 8,207 participants aged 45 ∼ 60 at baseline. Multivariate linear regression models using generalized estimating equations
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Urban-rural differences in the prevalence and associated factors of sarcopenia: A systematic review and meta-analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-03 Xiaoyan Li, Rongyun Wang, Zhuoer Hou, Qiuhua Sun
Loss of muscle mass, muscle strength, and/or physical performance due to aging is known as sarcopenia. Regardless of how serious this illness is, no single diagnostic criteria have been established. Much research conducted recently has demonstrated differences between built environment characteristics (i.e., urban and rural) and the occurrence of sarcopenia; however, variations in sarcopenia prevalence
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Interrelationships between physical multimorbidity, depressive symptoms and cognitive function among older adults in China, India and Indonesia: a four-way decomposition analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-03 Kanya Anindya, Yang Zhao, Thanh Hoang, John Tayu Lee, Sanjay Juvekar, Anand Krishnan, Vanessa Mbuma, Tarishi Sharma, Nawi Ng
This paper explores the role of depressive symptoms (mediator/moderator) in the association between physical multimorbidity (exposure) and cognitive function (outcome) among older adults in the three most populous middle-income countries. This study used cross-sectional data from China (2015 China Health and Retirement Longitudinal Study), India (2017/2018 Longitudinal Ageing Study in India), and Indonesia
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Self-rated health in old age, related factors and survival: A 20-Year longitudinal study within the Silver-MONICA cohort Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-29 Ariel Almevall, Albin Dahlin Almevall, Jerry Öhlin, Yngve Gustafson, Karin Zingmark, Johan Niklasson, Peter Nordström, Erik Rosendahl, Stefan Söderberg, Birgitta Olofsson
Self-rated health (SRH) offers insights into the evolving health demographics of an ageing population. To assess change in SRH from old age to very old age and their associations with health and well-being factors, and to investigate the association between SRH and survival. All participants in the MONICA 1999 re-examination born before 1940 ( = 1595) were included in the Silver-MONICA baseline cohort
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Grip strength buffers the harmful association between multimorbidity and depression among middle-aged and older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-28 Clément Blanchet, Miguel Peralta, Marcelo de Maio Nascimento, Élvio R. Gouveia, Gerson Ferrari, Tiago D. Ribeiro, Adilson Marques
Grip strength (GS) is associated to both multimorbidity and depression, however its possible moderating effect is unknown. This study aimed to investigate GS moderating effect on the association between multimorbidity and depression. Data from SHARE wave 8 was used. Participant were 41457 middle-aged and older adults (17954 men) from 18 European countries. A regression analysis was conducted for the
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Trends in incidence, mortality, dynamic needs and rapid evolution of healthcare in dementia Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-27 Ke-Zong Ma, Chaur-Jong Hu
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Prediction of decline in activities of daily living using motor performance tests in older adults requiring long-term care Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-27 Shinnosuke Hato, Yuta Hayashi, Hiroyuki Shimada
This study aimed to predict decline in activities of daily living (ADL) in older adults requiring long-term care, using motor performance tests. This prospective cohort study was conducted among 3948 older adults using day care services in Japan. ADL decline was assessed using the Functional Independence Measure at the start of day care service use and 12 months later. Grip strength (GS), one-leg standing
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Development of a weighted scoring model for social activities to predict disability incidents among older Japanese adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-27 Takahiro Shimoda, Kouki Tomida, Chika Nakajima, Ayuka Kawakami, Hiroyuki Shimada
Social activities contribute to health improvements in older adults, but methods for evaluating these activities are not yet established. We developed a scoring model for social activity, weighted by specific activities, to assess the association between disability incidence in older adults and social activities. Data were obtained from Japan's National Center for Geriatrics and Gerontology Study of
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Findings from a pragmatic cluster randomised controlled feasibility trial of a music and dance programme for community dwelling older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-24 Amanda M. Clifford, Pui-Sze Cheung, Nicola O’ Malley, Steven Byrne, Aoife Whiston, Brendan Kennelly, Tumeliwa Mphepo, Zohreh Eshghimanesh, Lehana Thabane, Quinette Louw, Hilary Moss, Rosemary Joan Gowran, Desmond O’ Neill, Liam Glynn, Catherine B. Woods, Catherine Maher, Ali Sheikhi, Jon Salsberg, Orfhlaith Ni Bhriain
Functional decline, chronic illness, reduced quality of life and increased healthcare utilisation are common in older adults. Evidence suggests music and dance can support healthy ageing in older adults. This study explored the feasibility, potential for effect and cost effectiveness of the () programme among community-dwelling older adults using a pragmatic cluster-randomised, controlled feasibility
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Association between handgrip strength weakness and asymmetry with incident hip fracture among older Chinese adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-23 Shengliang Zhou, Haibo Si, Limin Wu, Yuan Liu, Linbo Peng, Mingyang Li, Bin Shen
To evaluate the association between handgrip strength (HGS) weakness and asymmetry with incident hip fracture among older Chinese adults. Data was obtained from the 2011 and 2015 waves of the China Health and Retirement Longitudinal Study (CHARLS). HGS weakness was defined as maximal HGS 〈 28 kg in men and < 18 kg in women. HGS asymmetry was defined as the HGS ratio < 0.9 or 〉 1.1. Participants were
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Association between the sarcopenia-related traits and Parkinson's disease: A bidirectional two-sample Mendelian randomization study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-20 Yingqi She, Yaming He, Jianwei Wu, Ning Liu
To explore the causal association between sarcopenia-related traits and Parkinson's disease by Mendelian randomization (MR) approach. A genome-wide association study (GWAS) of sarcopenia-related traits was done at the UK Biobank (UKB). The traits were appendicular lean mass, low hand grip strength (including the European Working Group on Sarcopenia in Older People (EWGSOP) and the Foundation for the
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Cynaroside extends lifespan and improves the neurondegeneration diseases via insulin/IGF-1 signaling pathway in Caenorhabditis elegans Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-20 Yi Xiao, Yan Zhang, Linlu Li, Nian Jiang, Changyan Yu, Sanhua Li, Xinting Zhu, Fang Liu, Yun Liu
The evolutionarily conserved insulin/IGF-1 signaling pathway plays a central role in aging and aging related diseases such as neurodegeneration diseases. Inhibition of insulin/IGF-1 signaling pathway has been proposed as a effective way to extend lifespan and delay neurodegeneration diseases in different organisms. Cynaroside (Cyn), a flavonoid contained in many medical plants and in vegetables, had
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Changes in immune cell subtypes during ageing Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-20 Khin Aye Thin, Andrew Cross, Phonthep Angsuwatcharakon, Apiwat Mutirangura, Charoenchai Puttipanyalears, Steven W Edwards
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Differential modulation of corticomotor excitability in older compared to young adults following a single bout of strength -exercise Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-20 Ummatul Siddique, Ashlyn K. Frazer, Janne Avela, Simon Walker, Juha P. Ahtiainen, Meghan Tanel, Sergio Uribe, Yonas Akalu, Mohamad Rostami, Jamie Tallent, Dawson J. Kidgell
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Trajectories of cognitive decline in different domains prior to AD onset in persons with mild cognitive impairment Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-20 Manqiong Yuan, Meng Rong, Xianxian Long, Shuli Lian, Ya Fang
To explore the trajectories and the change-points of global and five domain-specific cognitive functions before the onset of Alzheimer's disease (AD). Data was retrieved from the Alzheimer's Disease Neuroimaging Initiative with follow-up from 2005 to 2022. Participants with mild cognitive impairment (MCI) at baseline and those who progressed to AD during follow-up were included. The time of AD onset
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Best practices for implementing a technology-based intervention protocol: Participant and researcher considerations Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-19 George Mois, Elizabeth A. Lydon, Vincent F. Mathias, Sarah E. Jones, Raksha A. Mudar, Wendy A. Rogers
Technology-based interventions present a promising approach to support health and wellness for older adults with a range of cognitive abilities. Technology can enhance access to interventions and support scaling of programs to reach more people. However, the use of technology for intervention delivery requires particular attention to users’ needs and preferences and ensuring the materials are adaptable
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Beyond clinical practice guidelines: The risk-treatment paradox in frail older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-13 Liang-Kung Chen
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The impact of frailty on initiation, continuation and discontinuation of secondary prevention medications following myocardial infarction Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-13 Hannah Doody, Justine Ayre, Adam Livori, Jenni Ilomäki, Viviane Khalil, J. Simon Bell, Jedidiah I Morton
To evaluate the association between frailty and initiating, continuing, or discontinuing secondary prevention medications following myocardial infarction (MI). We conducted a cohort study using linked health data, including all adults aged ≥65 years who discharged from hospital following MI from January 2013 to April 2018 in Victoria, Australia (N=29,771). The Hospital Frailty Risk Score (HFRS) was
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Effect of dual-task training on balance in older adults: A systematic review and meta-analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-09 Seda Ercan Yildiz, Oznur Fidan, Cagrı Gulsen, Ertugrul Colak, Gulsum Aydan Genc
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Dentition status and risk of frailty in older Chinese people: a 16-year prospective cohort study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-08 Shiqi Lin, Qi Yu, Jiajia Li, Xiaojin Yan
To explore associations of dentition status with frailty and death. Based on the “Chinese Longitudinal Healthy Longevity Survey (CLHLS) in 2002-2018”, a prospective cohort study was conducted that 21,159 participants not frail and aged ≥ 65 were included at baseline. The outcome was frailty and death. Frailty index (FI) was constructed based on 44 health items. The mediation role of high sensitivity
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Longitudinal associations between sensory and cognitive functioning in adults 60 years or older in Sweden and Denmark Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-07 Andreea-Corina Badache, Johan Rehnberg, Elina Mäki-Torkko, Stephen Widen, Stefan Fors
The objective of this study is to explore the bidirectional, longitudinal associations between self-reported sensory functions (hearing/vision) and cognitive functioning among older adults in Sweden and Denmark during the period 2004–2017. The study is based on data from The Survey of Health, Ageing and Retirement in Europe and consists of 3164 persons aged 60 to 93 years. Within-person associations
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Deterioration of fine motor skills and functional disability in patients with moderate-to-advanced Parkinson disease: A longitudinal follow-up study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-07 Yin-Chia Huang, Chien-Tai Hong, Wen-Chou Chi, Chia-Feng Yen, Hua- Fang Liao, Tsan-Hon Liou, Lung Chan
Parkinson disease (PD) caused substantially disability. The impairment of fine motor skills (FMSs) is correlated with the severity of functional disability (FD) cross-sectionally in people with PD (PwP). The present study investigated the decline in FMSs and the predictive value of baseline FMSs for the progression of FD. People with moderate-to-advanced PD who received two evaluations within 1–5 years
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Is polypharmacy a risk factor for aspiration pneumonia in older adults? A case-control study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-06 Haruko Suzuki, Akio Yamamoto, Kumiko Ono, Yoji Yamada, Yutaro Oki, Mineko Ohira, Akira Ishikawa
The incidence of aspiration pneumonia and the number of medicines prescribed increase with older age. Many medicines pose a risk for aspiration pneumonia, especially those that decrease swallowing function. Older adults with polypharmacy often receive a combination of these medicines. This study aimed to clarify whether polypharmacy is a risk factor for aspiration pneumonia. : Older adults aged ≥65
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Causal relationships of physical activity and leisure sedentary behaviors with COPD: A Mendelian randomization study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-05 Yixuan Gao, Conghui Li, Junping Li, Ling Li
Background Chronic diseases such as chronic obstructive pulmonary disease (COPD) have been linked to low levels of physical activity (PA) and higher frequency of leisure sedentary behavior (LSB). The main causes of COPD include respiratory and peripheral muscle dysfunction, low levels of PA, and LSB which are associated with a higher risk of developing COPD. The attribution relationship between PA
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Reducing the drug burden of sedative and anticholinergic medications in older adults: a scoping review of explicit decision criteria Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-05 Hector Rodríguez-Ramallo, Nerea Báez-Gutiérrez, Ángela Villalba-Moreno, Didiana Jaramillo Ruiz, Bernardo Santos-Ramos, Elena Prado-Mel, Susana Sanchez-Fidalgo
To describe the extent, characteristics, and knowledge gaps regarding explicit decision criteria for deprescribing drugs with anticholinergic or sedative properties (Ach/Sed) in older adults. Scoping review. Original studies, clinical trial protocols, grey literature, and Summaries of Product Characteristics. Searches targeting explicit decision criteria for deprescribing Ach/Sed were performed across
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Effect of long-term care insurance in a pilot city of China: Health benefits among 12,930 disabled older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-03 Lijun Zeng, Yue Zhong, Yuxiao Chen, Mei Zhou, Shaoyang Zhao, Jinhui Wu, Birong Dong, Qingyu Dou
The surge of disabled older people have brought enormous burdens to society. The aim of this study was to examine the impact of long-term care insurance (LTCI) implementation on mortality and changes in physical ability among disabled older adults. This was a prospective observational study based on data from the government-led LTCI program in a pilot city of China from 2017 to 2021. Administrative
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Intrinsic capacity and multimorbidity predicting incident disability–Insights from the I-Lan Longitudinal Aging Study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-03 Wei-Ju Lee, Li-Ning Peng, Ming-Hsien Lin, Ching-Hui Loh, Fei-Yuan Hsiao, Liang-Kung Chen
This longitudinal cohort study aimed to examine the effect of intrinsic capacity (IC) and multimorbidity on the development of new disabilities. The study utilized data from 1,009 participants without disabilities from the I-Lan Longitudinal Aging Study. Multivariable logistic regressions were employed to assess the predictive capability of IC (ranging from 0 to 100) and multimorbidity for incident
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Prevalence, perceptions, and experiences of frailty among older migrants from Low- and Middle-Income Countries to High Income Countries: A mixed method systematic review Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-02 Gideon Dzando, Paul Ward, Hailay Abrha Gesesew, Jessica Tyndall, Rachel C. Ambagtsheer
Frailty is increasingly becoming a public health concern, especially among vulnerable populations. Older migrants from Low- and Middle-Income Countries to High Income Countries present with poorer health and are at increased risk of becoming frail. This review aims to explore the prevalence, perceptions, and experiences of frailty among older migrants from Low- and Middle-Income Countries to High Income