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Association of Depressive Symptoms with Cardiovascular Events and Plasma BNP: A Prospective Cohort Study of the Elderly Chinese Population Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-12 Xiaoxu Wang, Jianming Shi, Xiaoyan Jiang, Xiaofeng Wang
To estimate the prevalence of depressive symptoms and to evaluate the associations of mild and significant depressive symptoms with cardiovascular events and plasma BNP levels (which are surrogate endpoints for cardiovascular events) among older adults in a population-based study. A population-based prospective study of 1,432 elderly people (aged 70-84 years and without cardiovascular disease) was
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Investigating Balance-Related Gait Patterns and Their Relationship with Maximum Torques Generated by the Hamstrings and Quadriceps in Older Adults - Results from the Baltimore Longitudinal Study of Aging Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-12 Seung-uk Ko, Gerald J Jerome, Eleanor M. Simonsick, Luigi Ferrucci
Balance-related gait patterns in older adults can be objectively discerned through the examination of gait parameters, maximum leg torques, and their interconnections. To investigate the correlation between leg muscle strength and balance during gait concerning functional performance in healthy older adults. Participants included 117 adults aged 60-95 years were recruited from the Baltimore Longitudinal
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Socially Assistive Robots for Individuals with Alzheimer's Disease: A Scoping Review Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-12 Vania Karami, Mark J. Yaffe, Genevieve Gore, AJung Moon, Samira Abbasgholizadeh Rahimi
The most common form of dementia, Alzheimer's Disease (AD), is challenging for both those affected as well as for their care providers, and caregivers. Socially assistive robots (SARs) offer promising supportive care to assist in the complex management associated with AD. To conduct a scoping review of published articles that proposed, discussed, developed or tested SAR for interacting with AD patients
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Joint trajectories of physical frailty and social frailty and associations with adverse outcomes: A prospective cohort study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-05 Qinqin Liu, Yuli Huang, Shuai Gao, Binlin Wang, Yanyan Li, Huaxin Si, Wendie Zhou, Jiaqi Yu, Hejing Chen, Cuili Wang
We examined joint trajectories of physical frailty and social frailty as well as their associations with adverse outcomes. We conducted a prospective cohort study by using five waves of national data from China Health and Retirement Longitudinal Study (CHARLS 2011-2020), involving 4531 participants aged ≥60 years. We identified 4-year trajectories at three examinations from 2011 to 2015 using parallel
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The Social and Cognitive Online Training (SCOT) project: a digital randomized controlled trial to promote socio-cognitive wellbeing in older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-05 Giulia Funghi, Claudia Meli, Arianna Cavagna, Lisa Bisoffi, Francesca Zappini, Costanza Papagno, Alessandra Dodich
Objectives: Effective prevention programs targeting risk factors for cognitive decline in the elderly are recommended given the progressive increase in the ageing of the general population. The Social and Cognitive Online Training (SCOT) project is a randomized, controlled, parallel clinical trial designed to prevent the age-related decline in executive and social functions.
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Social engagement and cognitive impairment among nursing home residents: The role of sensory impairment Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-05 Shu Xu, William M. Jesdale, Catherine E. Dubé, Natalia N. Nielsen, Emily A. McPhillips, Kate L. Lapane
Using US national nursing home data, this cross-sectional study sought to evaluate 1) the association between lack of social engagement and level of cognitive impairment; and 2) the extent to which this association differs by hearing and visual impairment. Our sample included 793,846 nursing home residents aged ≥ 50 years. The Index of Social Engagement was categorized as none/lower (0, 1, 2) or higher
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Longitudinal relationship between grip strength and cognitive function in a European population older than 50 years: A cross-lagged panel model Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-05 Man Cui, Juan Wang, Miao Deng, Hailan Meng, Yanshuai Fan, Chaoyue Ku, Ruizhe Wang, Binbin Wu, Man Dai, Zhiguang Ping
The aim of this study was to investigate the dynamic longitudinal relationship between grip strength and cognitive function. 6175 participants aged ≥50 years were included in the study using three waves of follow-up data from the Survey of Health, Ageing, and Retirement in Europe in 2015 (T1), 2017 (T2) and 2019 (T3). Cognitive function was assessed using numeracy, verbal fluency, immediate recall
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Cognitively high-performing oldest old individuals are physically active and have strong motor skills–A study of the Danish 1905 and 1915 birth cohorts Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-04 Maja Hermansen, Marianne Nygaard, Qihua Tan, Bernard Jeune, Maria Semkovska, Kaare Christensen, Mikael Thinggaard, Jonas Mengel-From
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Frailty and brain changes in older adults without cognitive impairment: a scoping review Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-04 Gabriela Cabett Cipolli, Isadora Cristina Ribeiro, Clarissa Lin Yasuda, Márcio Luiz Figueredo Balthazar, André Fattori, Mônica Sanches Yassuda
Little is known about changes in the brain associated with frailty, in particular, which brain areas could be related to frailty in older people without cognitive impairment. This scoping review mapped evidence on functional and/or structural brain changes in frail older adults without cognitive impairment. The methodology proposed by the JBI® was used in this study. The search in PubMed, PubMed PMC
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The influence of intergenerational support on cognitive functioning among middle-aged Chinese: Moderation by personal income Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-04 Ping Wang, Chunhai Tao
To analyze the effects of personal income on the relationship between intergenerational support (IS) and cognitive functioning. Data were obtained from four waves of nationally representative surveys of the 2011–2018 China Health and Retirement Longitudinal Study (CHARLS), involving 8,207 participants aged 45 ∼ 60 at baseline. Multivariate linear regression models using generalized estimating equations
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Urban-rural differences in the prevalence and associated factors of sarcopenia: A systematic review and meta-analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-03 Xiaoyan Li, Rongyun Wang, Zhuoer Hou, Qiuhua Sun
Loss of muscle mass, muscle strength, and/or physical performance due to aging is known as sarcopenia. Regardless of how serious this illness is, no single diagnostic criteria have been established. Much research conducted recently has demonstrated differences between built environment characteristics (i.e., urban and rural) and the occurrence of sarcopenia; however, variations in sarcopenia prevalence
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Interrelationships between physical multimorbidity, depressive symptoms and cognitive function among older adults in China, India and Indonesia: a four-way decomposition analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-03-03 Kanya Anindya, Yang Zhao, Thanh Hoang, John Tayu Lee, Sanjay Juvekar, Anand Krishnan, Vanessa Mbuma, Tarishi Sharma, Nawi Ng
This paper explores the role of depressive symptoms (mediator/moderator) in the association between physical multimorbidity (exposure) and cognitive function (outcome) among older adults in the three most populous middle-income countries. This study used cross-sectional data from China (2015 China Health and Retirement Longitudinal Study), India (2017/2018 Longitudinal Ageing Study in India), and Indonesia
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Self-rated Health in Old Age, related factors and Survival: A 20-Year Longitudinal Study within the Silver-MONICA cohort. Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-29 Ariel Almevall, Albin Dahlin Almevall, Jerry Öhlin, Yngve Gustafson, Karin Zingmark, Johan Niklasson, Peter Nordström, Erik Rosendahl, Stefan Söderberg, Birgitta Olofsson
Self-rated health (SRH) offers insights into the evolving health demographics of an ageing population. To assess change in SRH from old age to very old age and their associations with health and well-being factors, and to investigate the association between SRH and survival. All participants in the MONICA 1999 re-examination born before 1940 (n=1595) were included in the Silver-MONICA baseline cohort
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Grip strength buffers the harmful association between multimorbidity and depression among middle-aged and older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-28 Clément Blanchet, Miguel Peralta, Marcelo de Maio Nascimento, Élvio R. Gouveia, Gerson Ferrari, Tiago D. Ribeiro, Adilson Marques
Grip strength (GS) is associated to both multimorbidity and depression, however its possible moderating effect is unknown. This study aimed to investigate GS moderating effect on the association between multimorbidity and depression. Data from SHARE wave 8 was used. Participant were 41457 middle-aged and older adults (17954 men) from 18 European countries. A regression analysis was conducted for the
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Trends in incidence, mortality, dynamic needs and rapid evolution of healthcare in dementia Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-27 Ke-Zong Ma, Chaur-Jong Hu
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Prediction of decline in activities of daily living using motor performance tests in older adults requiring long-term care Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-27 Shinnosuke Hato, Yuta Hayashi, Hiroyuki Shimada
This study aimed to predict decline in activities of daily living (ADL) in older adults requiring long-term care, using motor performance tests. This prospective cohort study was conducted among 3948 older adults using day care services in Japan. ADL decline was assessed using the Functional Independence Measure at the start of day care service use and 12 months later. Grip strength (GS), one-leg standing
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Development of a weighted scoring model for social activities to predict disability incidents among older Japanese adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-27 Takahiro Shimoda, Kouki Tomida, Chika Nakajima, Ayuka Kawakami, Hiroyuki Shimada
Social activities contribute to health improvements in older adults, but methods for evaluating these activities are not yet established. We developed a scoring model for social activity, weighted by specific activities, to assess the association between disability incidence in older adults and social activities. Data were obtained from Japan's National Center for Geriatrics and Gerontology Study of
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Findings from a pragmatic cluster randomised controlled feasibility trial of a music and dance programme for community dwelling older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-24 Amanda M. Clifford, Pui-Sze Cheung, Nicola O’ Malley, Steven Byrne, Aoife Whiston, Brendan Kennelly, Tumeliwa Mphepo, Zohreh Eshghimanesh, Lehana Thabane, Quinette Louw, Hilary Moss, Rosemary Joan Gowran, Desmond O’ Neill, Liam Glynn, Catherine B. Woods, Catherine Maher, Ali Sheikhi, Jon Salsberg, Orfhlaith Ni Bhriain
Functional decline, chronic illness, reduced quality of life and increased healthcare utilisation are common in older adults. Evidence suggests music and dance can support healthy ageing in older adults. This study explored the feasibility, potential for effect and cost effectiveness of the () programme among community-dwelling older adults using a pragmatic cluster-randomised, controlled feasibility
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Association between handgrip strength weakness and asymmetry with incident hip fracture among older Chinese adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-23 Shengliang Zhou, Haibo Si, Limin Wu, Yuan Liu, Linbo Peng, Mingyang Li, Bin Shen
To evaluate the association between handgrip strength (HGS) weakness and asymmetry with incident hip fracture among older Chinese adults. Data was obtained from the 2011 and 2015 waves of the China Health and Retirement Longitudinal Study (CHARLS). HGS weakness was defined as maximal HGS 〈 28 kg in men and < 18 kg in women. HGS asymmetry was defined as the HGS ratio < 0.9 or 〉 1.1. Participants were
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Association between the sarcopenia-related traits and Parkinson's disease: A bidirectional two-sample Mendelian randomization study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-20 Yingqi She, Yaming He, Jianwei Wu, Ning Liu
To explore the causal association between sarcopenia-related traits and Parkinson's disease by Mendelian randomization (MR) approach. A genome-wide association study (GWAS) of sarcopenia-related traits was done at the UK Biobank (UKB). The traits were appendicular lean mass, low hand grip strength (including the European Working Group on Sarcopenia in Older People (EWGSOP) and the Foundation for the
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Cynaroside extends lifespan and improves the neurondegeneration diseases via insulin/IGF-1 signaling pathway in Caenorhabditis elegans Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-20 Yi Xiao, Yan Zhang, Linlu Li, Nian Jiang, Changyan Yu, Sanhua Li, Xinting Zhu, Fang Liu, Yun Liu
The evolutionarily conserved insulin/IGF-1 signaling pathway plays a central role in aging and aging related diseases such as neurodegeneration diseases. Inhibition of insulin/IGF-1 signaling pathway has been proposed as a effective way to extend lifespan and delay neurodegeneration diseases in different organisms. Cynaroside (Cyn), a flavonoid contained in many medical plants and in vegetables, had
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Changes in immune cell subtypes during ageing Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-20 Khin Aye Thin, Andrew Cross, Phonthep Angsuwatcharakon, Apiwat Mutirangura, Charoenchai Puttipanyalears, Steven W Edwards
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Differential modulation of corticomotor excitability in older compared to young adults following a single bout of strength -exercise Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-20 Ummatul Siddique, Ashlyn K. Frazer, Janne Avela, Simon Walker, Juha P. Ahtiainen, Meghan Tanel, Sergio Uribe, Yonas Akalu, Mohamad Rostami, Jamie Tallent, Dawson J. Kidgell
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Trajectories of cognitive decline in different domains prior to AD onset in persons with mild cognitive impairment Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-20 Manqiong Yuan, Meng Rong, Xianxian Long, Shuli Lian, Ya Fang
To explore the trajectories and the change-points of global and five domain-specific cognitive functions before the onset of Alzheimer's disease (AD). Data was retrieved from the Alzheimer's Disease Neuroimaging Initiative with follow-up from 2005 to 2022. Participants with mild cognitive impairment (MCI) at baseline and those who progressed to AD during follow-up were included. The time of AD onset
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Best practices for implementing a technology-based intervention protocol: Participant and researcher considerations Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-19 George Mois, Elizabeth A. Lydon, Vincent F. Mathias, Sarah E. Jones, Raksha A. Mudar, Wendy A. Rogers
Technology-based interventions present a promising approach to support health and wellness for older adults with a range of cognitive abilities. Technology can enhance access to interventions and support scaling of programs to reach more people. However, the use of technology for intervention delivery requires particular attention to users’ needs and preferences and ensuring the materials are adaptable
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Beyond clinical practice guidelines: The risk-treatment paradox in frail older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-13 Liang-Kung Chen
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The impact of frailty on initiation, continuation and discontinuation of secondary prevention medications following myocardial infarction Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-13 Hannah Doody, Justine Ayre, Adam Livori, Jenni Ilomäki, Viviane Khalil, J. Simon Bell, Jedidiah I Morton
To evaluate the association between frailty and initiating, continuing, or discontinuing secondary prevention medications following myocardial infarction (MI). We conducted a cohort study using linked health data, including all adults aged ≥65 years who discharged from hospital following MI from January 2013 to April 2018 in Victoria, Australia (N=29,771). The Hospital Frailty Risk Score (HFRS) was
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Effect of dual-task training on balance in older adults: A systematic review and meta-analysis Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-09 Seda Ercan Yildiz, Oznur Fidan, Cagrı Gulsen, Ertugrul Colak, Gulsum Aydan Genc
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Dentition status and risk of frailty in older Chinese people: a 16-year prospective cohort study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-08 Shiqi Lin, Qi Yu, Jiajia Li, Xiaojin Yan
: To explore associations of dentition status with frailty and death. : Based on the “Chinese Longitudinal Healthy Longevity Survey (CLHLS) in 2002-2018”, a prospective cohort study was conducted that 21,159 participants not frail and aged ≥ 65 were included at baseline. The outcome was frailty and death. Frailty index (FI) was constructed based on 44 health items. The mediation role of high sensitivity
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Longitudinal associations between sensory and cognitive functioning in adults 60 years or older in Sweden and Denmark Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-07 Andreea-Corina Badache, Johan Rehnberg, Elina Mäki-Torkko, Stephen Widen, Stefan Fors
The objective of this study is to explore the bidirectional, longitudinal associations between self-reported sensory functions (hearing/vision) and cognitive functioning among older adults in Sweden and Denmark during the period 2004-2017. The study is based on data from The Survey of Health, Ageing and Retirement in Europe and consists of 3164 persons aged 60 to 93 years. Within-person associations
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Deterioration of fine motor skills and functional disability in patients with moderate-to-advanced Parkinson disease: A longitudinal follow-up study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-07 Yin-Chia Huang, Chien-Tai Hong, Wen-Chou Chi, Chia-Feng Yen, Hua- Fang Liao, Tsan-Hon Liou, Lung Chan
Parkinson disease (PD) caused substantially disability. The impairment of fine motor skills (FMSs) is correlated with the severity of functional disability (FD) cross-sectionally in people with PD (PwP). The present study investigated the decline in FMSs and the predictive value of baseline FMSs for the progression of FD. People with moderate-to-advanced PD who received two evaluations within 1–5 years
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Is polypharmacy a risk factor for aspiration pneumonia in older adults? A case-control study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-06 Haruko Suzuki, Akio Yamamoto, Kumiko Ono, Yoji Yamada, Yutaro Oki, Mineko Ohira, Akira Ishikawa
The incidence of aspiration pneumonia and the number of medicines prescribed increase with older age. Many medicines pose a risk for aspiration pneumonia, especially those that decrease swallowing function. Older adults with polypharmacy often receive a combination of these medicines. This study aimed to clarify whether polypharmacy is a risk factor for aspiration pneumonia. : Older adults aged ≥65
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Causal relationships of physical activity and leisure sedentary behaviors with COPD: A Mendelian randomization study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-05 Yixuan Gao, Conghui Li, Junping Li, Ling Li
Background Chronic diseases such as chronic obstructive pulmonary disease (COPD) have been linked to low levels of physical activity (PA) and higher frequency of leisure sedentary behavior (LSB). The main causes of COPD include respiratory and peripheral muscle dysfunction, low levels of PA, and LSB which are associated with a higher risk of developing COPD. The attribution relationship between PA
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Reducing the drug burden of sedative and anticholinergic medications in older adults: a scoping review of explicit decision criteria Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-05 Hector Rodríguez-Ramallo, Nerea Báez-Gutiérrez, Ángela Villalba-Moreno, Didiana Jaramillo Ruiz, Bernardo Santos-Ramos, Elena Prado-Mel, Susana Sanchez-Fidalgo
To describe the extent, characteristics, and knowledge gaps regarding explicit decision criteria for deprescribing drugs with anticholinergic or sedative properties (Ach/Sed) in older adults. Scoping review. Original studies, clinical trial protocols, grey literature, and Summaries of Product Characteristics. Searches targeting explicit decision criteria for deprescribing Ach/Sed were performed across
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Effect of long-term care insurance in a pilot city of China: Health benefits among 12,930 disabled older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-03 Lijun Zeng, Yue Zhong, Yuxiao Chen, Mei Zhou, Shaoyang Zhao, Jinhui Wu, Birong Dong, Qingyu Dou
The surge of disabled older people have brought enormous burdens to society. The aim of this study was to examine the impact of long-term care insurance (LTCI) implementation on mortality and changes in physical ability among disabled older adults. This was a prospective observational study based on data from the government-led LTCI program in a pilot city of China from 2017 to 2021. Administrative
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Intrinsic capacity and multimorbidity predicting incident disability–Insights from the I-Lan Longitudinal Aging Study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-03 Wei-Ju Lee, Li-Ning Peng, Ming-Hsien Lin, Ching-Hui Loh, Fei-Yuan Hsiao, Liang-Kung Chen
Objectives: This longitudinal cohort study aimed to examine the effect of intrinsic capacity (IC) and multimorbidity on the development of new disabilities.
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Prevalence, perceptions, and experiences of frailty among older migrants from Low- and Middle-Income Countries to High Income Countries: A mixed method systematic review Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-02 Gideon Dzando, Paul Ward, Hailay Abrha Gesesew, Jessica Tyndall, Rachel C. Ambagtsheer
Frailty is increasingly becoming a public health concern, especially among vulnerable populations. Older migrants from Low- and Middle-Income Countries to High Income Countries present with poorer health and are at increased risk of becoming frail. This review aims to explore the prevalence, perceptions, and experiences of frailty among older migrants from Low- and Middle-Income Countries to High Income
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Social participation and functional disability trajectories in the last three years of life: The Japan Gerontological Evaluation Study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-02 Takayuki Ueno, Junko Saito, Hiroshi Murayama, Masashige Saito, Maho Haseda, Katsunori Kondo, Naoki Kondo
: Functional disability has various patterns from onset until death. Although social participation is a known protective factor against functional disability among older individuals, it is unclear whether social participation is associated with the trajectory patterns of functional disability prior to death. This study assessed the association between social participation, specifically in horizontal
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Transition of visceral adiposity index and risk of cardiovascular disease in middle-aged and older Chinese adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-01 Yougen Yuan, Xiangming Hu, Junguo Jin, Jieliang Liu, Lujing Jiang, Guang Li, Yingling Zhou, Yanqiu Ou, Haojian Dong
Visceral obesity and the lifetime risk of cardiovascular disease (CVD) have received increasing attention. However, the relationship between dynamic changes in visceral obesity and CVD has not been studied. We aimed to determine the association of visceral adiposity index (VAI) transition with CVD risk. A total of 5395 participants were recruited in 2011-2012 and followed up until 2018 from the China
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Multifaceted roles of sleep on healthy longevity Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-01 L, i, a, n, g, -, K, u, n, g, , C, h, e, n
Abstract not available
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Weight loss and functional decline in older Japanese people: A cohort study using large-scale claims data Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-01 Sachiko Ono, Yusuke Sasabuchi, Hayato Yamana, Isao Yokota, Akira Okada, Hiroki Matsui, Shunsuke Itai, Kazumichi Yonenaga, Kanata Tonosaki, Rinji Watanabe, Yosuke Ono, Hideo Yasunaga, Kazuto Hoshi
The association between weight loss and subsequent functional decline is uncertain. The study aims to elucidate the association between weight loss over a year and subsequent functional decline requiring assistance in performing their activities of daily living in older individuals. The study used data from the publicly funded Long-Term Care Insurance service in Japan, which provides coverage for long-term
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C-reactive protein and cognitive impairment: a bidirectional Mendelian randomization study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-02-01 Wenhuo Xie, Chenghua Kong, Wei Luo, Jiaping Zheng, Yu Zhou
Objectives While C-reactive protein (CRP) has been solidly linked as a risk factor for cognitive impairment, observational research alone cannot definitively demonstrate a causal relationship. This study therefore sought to determine whether there was an association between CRP and the development of cognitive impairment. Methods This study employed bidirectional Mendelian randomization (MR) to investigate
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Examining the role of attention focus walking training on conscious motor processing during rehabilitation by older adults at risk of falling: A randomized controlled trial Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-28 Toby C.T. Mak, Shamay S.M. Ng, Melody C.Y. Leung, Thomson W.L. Wong
This study examined the impact of walking training with different attention focus instructions on real-time conscious motor processing and fall-related rehabilitation outcomes in older adults at risk of falling. A total of 102 community-dwelling older adults (mean age = 75.2 years, SD = 6.8 years) were randomly assigned to three groups: no attention focus walking group (NAFWG), external attention focus
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Effects of Resistance Training Associated with a Verbal Fluency Task on Physical Performance and Cognitive Function in Frail Nursing Home Residents Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-28 Hélio José Coelho-Júnior, Erivaldo Machado Araújo, Marco Carlos Uchida, Emanuele Marzetti, Samuel da Silva Aguiar
Objectives Studies examining the effects of dual-task resistance training (RT) o nursing-home residents are still scarce. To add knowledge to this field, the present study compared the effects of 12-week RT and RT plus cognitive task (COG) programs on physical performance and cognitive function in a sample of frail nursing home residents. Methods This is an experimental study that combined data from
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Related risk factors for age-dependent telomere shortening change with age from the perspective of life course Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-26 Yin Chen, XiWen Ding, Ayizuhere Aierken, Yuan Chen, Ying Li
Background Many related factors can accelerate the age-dependent telomere shortening, but some problems remain unresolved. This study aimed to assess the risk factors of telomere attrition at different age stages. Methods This study was a population-based nationally representative survey study. All data were collected using a standard methodology by the national surveillance system. Quantitative polymerase
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Multiple long-term conditions, loneliness and social isolation: A scoping review of recent quantitative studies Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-26 Hilda Hounkpatin, Glenn Simpson, Miriam Santer, Andrew Farmer, Hajira Dambha-Miller
Multiple long-term conditions (MLTC), loneliness and social isolation are common in older adults. Recent studies have explored the association of MLTC with loneliness and social isolation. This scoping review aimed to map this current evidence and identify gaps in the literature. A scoping review was conducted following the PRISMA guidelines for scoping reviews. Ovid Medline, Embase, CINAHL, The Cochrane
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Causal association of rheumatoid arthritis with frailty and the mediation role of inflammatory cytokines: A Mendelian randomization study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-24 Long Wen, Jingwen Fan, Xuezhong Shi, Huiping Zhou, Yongli Yang, Xiaocan Jia
Previous observational studies have suggested the association between rheumatoid arthritis (RA) and frailty. However, it remains obscure whether this association is causal. This study aims to investigate the causal association of RA with frailty and the mediation effect of inflammatory cytokines using Mendelian randomization (MR) design. Summary-level data for RA ( = 58,284), frailty index (FI) ( =
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Physical activity positively impacts disability outcomes during transition from midlife to early older age irrespective of body mass index Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-23 Terrie Vasilopoulos, David Drozda, Heather K. Vincent
We examined the effects of physical activity (PA) and body mass index (BMI) longitudinal patterns (trajectories) on subjective measures of mobility, function, and disability in adults and assessed whether effects of PA trajectories on function varied due to BMI. Group-based trajectory analyses were used to determine patterns of change in PA and BMI using data from the Health and Retirement Study 1931–1941
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Effectiveness of a combined lifestyle intervention for older people in long-term care: A randomized controlled trial Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-23 Andrea Conti, Diego Concina, Annalisa Opizzi, Agatino Sanguedolce, Carmela Rinaldi, Sophia Russotto, Elena Grossini, Carla Maria Gramaglia, Patrizia Zeppegno, Massimiliano Panella
Lifestyle medicine interventions combining physical, nutritional, and psychological components have been found effective in general older population. However, evidence from the long-term care (LTC) is scarce. We conducted a pragmatic, two-arm, parallel group, superiority randomized controlled trial. Residents living in a LTC facility for one or more years, able to discern and to express informed consent
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Association of objectively measured physical activity with incidence disability in older adults with/without social isolation Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-23 Masanori Morikawa, Kenji Harada, Satoshi Kurita, Kazuya Fujii, Chiharu Nishijima, Daisuke Kakita, Hiroyuki Shimada
This study aimed to investigate association between objectively measured physical activities with incidence disability in older adults with and without social isolation. This 5-year longitudinal observational study used a population-based study from a sub-cohort of the National Center for Geriatrics and Gerontology Study of Geriatric Syndrome. In Japan, Incident disability is defined as a new case
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Longitudinal analysis of the mediating role of self-perception of aging in the relationship between frailty and intrinsic capacity: A cross-lagged mediation model Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-22 Junjun Sun, Ning Zhou, Huimin Zhang, Huimin Wu, Feifei Wang, Yanyan Luo
The causal relationship between intrinsic capacity and frailty in older adults, as well as the underlying temporal mechanisms, remained poorly understood. The study aimed to investigate the causal association between intrinsic capacity and frailty while exploring the potential mediating role of self-perception of aging. A survey was conducted with a sample of 429 participants who completed measures
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Divergent clinical implications of elevated serum vitamin B12 in all-cause mortality based on different origins Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-20 Liang-Kung Chen
Abstract not available
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Adverse outcomes of intrinsic capacity in older adults: A scoping review Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-17 Yiyi Yang, Guifen Ma, Suhong Wei, Xiaoqin Wei, Bailing Yan, Yue Yuan, Yajing Chen, Jiangxia Qin, Yuxia Ma
Background and Purpose Intrinsic capacity (IC) has been shown to have the greatest impact on an individual's health status and health trajectory and can independently predict adverse outcomes such as mortality and care dependency in older adults. However, the current understanding of adverse outcomes associated with IC is incomplete.
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Trends in dementia incidence and mortality, and dynamic changes in comorbidity and healthcare utilization from 2004–2017: a Taiwan national cohort study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-14 Shih-Tsung Huang, Ching-Hui Loh, Chi-Hung Lin, Fei-Yuan Hsiao, Liang-Kung Chen
Aims This study aims to ascertain dementia incidence from 2004-2017 in Taiwan, and to examine the disease course in comorbidity, treatments, healthcare usage, and mortality among older people with incident dementia preceding the diagnosis of dementia and afterwards. Methods Taiwan National Health Insurance data on people aged≥65 years with incident dementia from January 2004 to December 2017 were excerpted
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Development and validation of a medication-based risk prediction model for acute kidney injury in older outpatients Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-15 Mee Yeon Lee, Kyu-Nam Heo, Suhyun Lee, Young-Mi Ah, Jaekyu Shin, Ju-Yeun Lee
Older adults are at an increased risk of acute kidney injury (AKI), particularly in community settings, often due to medications. Effective prevention hinges on identifying high-risk patients, yet existing models for predicting AKI risk in older outpatients are scarce, particularly those incorporating medication variables. We aimed to develop an AKI risk prediction model that included medication-related
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Longitudinal trajectories of handgrip strength and their association with motoric cognitive risk syndrome in older adults Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-15 Hui Chang, Yu Zhao
To identify heterogeneous developmental trajectories of handgrip strength (HGS) in Chinese older adults and to explore the relationship between different developmental trajectories and motoric cognitive risk syndrome (MCR). We used three waves of longitudinal data from the China Health and Retirement Longitudinal Study from 2011 to 2015, which involved 3773 older adults. Growth mixture modeling (GMM)
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Healthy aging trajectories and their predictors among Chinese older adults: Evidence from a 7-year nationwide prospective cohort study Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-15 Xu Wang, Jinzhao Xie, Menglin Shang, Ping Yin, Jing Gu
This study aimed to identify healthy aging trajectories of Chinese older adults, and explore the factors contributing to these trajectories. We used data from four waves (2011–2018) of China Health and Retirement Longitudinal Study. We developed a healthy aging metric based on the healthy aging framework of World Health Organization (WHO) and Bayesian multilevel item response theory (IRT) method. The
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A combined circulating microRNA panel predicts the risk of vascular calcification in community-dwelling older adults with age strata differences Arch. Gerontol. Geriatr. (IF 4.0) Pub Date : 2024-01-15 Szu-Ying Lee, Chia-Ter Chao, Der-Sheng Han, Chih-Kang Chiang, Kuan-Yu Hung