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Thank you to our 2023 reviewers Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-12-02
Abstract not available
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Gaining insights into virotherapy with canine models Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-12-02 Jacob L. Léger, Lee-Hwa Tai
Abstract not available
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Targeting mesothelin in cancer Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-12-03 Cem Elbi
Abstract not available
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miR-146a: Overcoming coldness in ovarian cancer Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-12-03 Yanqi Ye, Nanhai G. Chen
Abstract not available
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New advances in cancer therapy targeting TGF-β signaling pathways Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-12-03 Minyue Shou, Hanyu Zhou, Ling Ma
Abstract not available
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The Role and Application of Vesicles in Triple-negative Breast Cancer: Opportunities and Challenges Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-23 Ya-Nan Wei, Chun-Yan Yan, Meng-Lu Zhao, Xi-He Zhao
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Bispecific CD33/CD123 targeted chimeric antigen receptor T cells for the treatment of acute myeloid leukemia Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-20 Justin C. Boucher, Bishwas Shrestha, Paresh Vishwasrao, Mark Leick, Estelle V. Cervantes, Tayyebb Ghafoor, Kayla Reid, Kristen Spitler, Bin Yu, Brian C. Betts, Jose A. Guevara-Patino, Marcela V. Maus, Marco L. Davila
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CM082 Enhances the Efficacy of Chemotherapeutic Drugs by Inhibiting the Drug Efflux Function of ABCG2 Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-10 Lejia Xu, Jiwei Huang, Jie Liu, Yun Xi, Zongheng Zheng, Kenneth K.W. To, Zhen Chen, Fang Wang, Yongming Zhang, Liwu Fu
Abstract not available
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Beyond ENO1, emerging roles and targeting strategies of other enolases in cancers Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-10 Jiaojiao Ni, Yihui Huang, Chaoqun Li, Qian Yin, Jieer Ying
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Molecular Therapy Oncology: What’s in a name? Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-10 Timothy P. Cripe
Abstract not available
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Kinetic analysis of oncolytic OrfV-induced innate and adaptive immune responses in a murine model of late-stage ovarian cancer Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-10 Jessica A. Minott, Jacob P. van Vloten, Jake G.E. Yates, Lisa A. Santry, Kathy Matuszewska, Madison Pereira, Melanie M. Goens, Alicia M. Viloria-Petit, Geoffrey A. Wood, Khalil Karimi, James J. Petrik, Byram W. Bridle, Sarah K. Wootton
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Pre-treatment with systemic agents for advanced NSCLC elicits changes in the phenotype of autologous T cell therapy products Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-10 Charlotte O’Brien Gore, Amy Billman, Suchete Hunjan, Jayne Colebrook, Desmond Choy, Wilson Li, Jack Haynes, Jennifer Wade, Emily Hobern, Louisa McDonald, Sophie Papa, Martijn Brugman, Shahram Kordasti, Claudia Montiel-Equihua
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Retraction Notice to: miR-140-3p Inhibits Cutaneous Melanoma Progression by Disrupting AKT/p70S6K and JNK Pathways through ABHD2 Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-03 Yuanmin He, Yan Yang, Yongmei Liao, Jixiang Xu, Li Liu, Changqiang Li, Xia Xiong
Abstract not available
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Dual blockade of CD47 and CD24 signaling using a novel bispecific antibody fusion protein enhances macrophage immunotherapy Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-04 Yun Yang, He Wu, Yan Yang, Yan Kang, Runjia He, Bei Zhou, Huaizu Guo, Jing Zhang, Jianqin Li, Chunpo Ge, Tianyun Wang
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Treatment with the PPARα agonist fenofibrate improves the efficacy of CD8+ T cell therapy for melanoma Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-03 Mohadeseh Hasanpourghadi, Arezki Chekaoui, Sophia Kurian, Raj Kurupati, Robert Ambrose, Wynetta Giles-Davis, Amara Saha, Xu Xiaowei, Hildegund C.J. Ertl
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Bacterial cancer therapy using the attenuated fowl-adapted Salmonella enterica serovar Gallinarum Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-02 Daejin Lim, Kwangsoo Kim, Taner Duysak, EunA. So, Jae-Ho Jeong, Hyon E. Choy
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Improved oncolytic activity of a reovirus mutant that displays enhanced virus spread due to reduced cell attachment Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-11-02 Francisca Cristi, Maiah Walters, Nashae Narayan, Kate Agopsowicz, Mary M. Hitt, Maya Shmulevitz
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Targeting the lactic acid metabolic pathway for antitumor therapy Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-10-31 Zhi Li, Jiuwei Cui
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Replication-incompetent influenza A viruses armed with IFN-γ effectively mediate immune modulation and tumor destruction in mice harboring lung cancer Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-10-31 Ramona Meissner, Viktor Wixler, Franziska Paulina Wulfert, Jasmin Carina Jacob, Benjamin G. Hale, Thomas Robeck, Dörthe Masemann, Yvonne Boergeling, Stephan Ludwig
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A library of cancer testis specific T cell receptors for T cell receptor gene therapy Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-10-23 Marije A.J. de Rooij, Dennis F.G. Remst, Dirk M. van der Steen, Anne K. Wouters, Renate S. Hagedoorn, Michel G.D. Kester, Miranda H. Meeuwsen, Tassilo L.A. Wachsmann, Arnoud H. de Ru, Peter A. van Veelen, Els M.E. Verdegaal, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk
Abstract not available
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Peritoneal-directed chimeric oncolytic virus CF17 prevents malignant ascites and improves survival in gastric cancer peritoneal metastases Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-10-19 Annie Yang, Zhifang Zhang, Shyambabu Chaurasiya, Anthony K. Park, Jianming Lu, Sang-In Kim, Hannah Valencia, Yuman Fong, Yanghee Woo
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An epitope encoded by uORF of RNF10 elicits a therapeutic anti-tumor immune response Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-10-19 Lili Zeng, Wei Zheng, Jiahui Zhang, Jiawen Wang, Qing Ji, Xinglong Wu, Yaming Meng, Xiaofeng Zhu
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Neoadjuvant systemic oncolytic vesicular stomatitis virus is safe and may enhance long-term survivorship in dogs with naturally occurring osteosarcoma Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-10-14 Kelly M. Makielski, Aaron L. Sarver, Michael S. Henson, Kathleen M. Stuebner, Antonella Borgatti, Lukkana Suksanpaisan, Caitlin Preusser, Alexandru-Flaviu Tabaran, Ingrid Cornax, M. Gerard O’Sullivan, Andrea Chehadeh, Donna Groschen, Kelly Bergsrud, Sara Pracht, Amber Winter, Lauren J. Mills, Marc D. Schwabenlander, Melissa Wolfe, Michael A. Farrar, Gary R. Cutter, Shruthi Naik
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Oncolytic virotherapy targeting the IL15 pathway Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-10-11 So Young Yoo, Jeong Heo
Abstract not available
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Ligand-based, piggyBac-engineered CAR-T cells targeting EGFR are safe and effective against non-small cell lung cancers Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-10-11 Thanyavi Chinsuwan, Koichi Hirabayashi, Shuji Mishima, Aiko Hasegawa, Miyuki Tanaka, Hidemi Mochizuki, Akihito Shimoi, Takashi Murakami, Shigeki Yagyu, Kimihiro Shimizu, Yozo Nakazawa
Abstract not available
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Advancements in CRISPR screens for the development of cancer immunotherapy strategies Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-10-05 Yan-Ruide Li, Zibai Lyu, Yanxin Tian, Ying Fang, Yichen Zhu, Yuning Chen, Lili Yang
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A novel GPI-anchored dominant-negative TGF-β receptor II renders T cells unresponsive to TGF-β signaling Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-09-25 Sven H. Petersen, Kays Al Badawy, Richard Hopkins, Dang L. Vu, Mehran Rahmani, Sonia M.P. Maia, John E. Connolly
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Breaking the barriers in cancer care: The next generation of herpes simplex virus-based oncolytic immunotherapies for cancer treatment Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-09-19 Nikhil I. Khushalani, Kevin J. Harrington, Alan Melcher, Praveen K. Bommareddy, Dmitriy Zamarin
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Ligand-based, piggyBac-engineered CAR-T cells targeting EGFR are safe and effective against non-small cell lung cancers Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-09-16 Thanyavi Chinsuwan, Koichi Hirabayashi, Shuji Mishima, Aiko Hasegawa, Miyuki Tanaka, Hidemi Mochizuki, Akihito Shimoi, Takashi Murakami, Shigeki Yagyu, Kimihiro Shimizu, Yozo Nakazawa
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Allogeneic tumor cell-derived extracellular vesicles stimulate CD8 T cell response in colorectal cancer Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-09-16 Travis J. Gates, Dechen Wangmo, Xianda Zhao, Subbaya Subramanian
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miR-146a inhibits ovarian tumor growth in vivo via targeting immunosuppressive neutrophils and enhancing CD8+ T cell infiltration Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-09-13 Rui Chen, Elaina Coleborn, Chintan Bhavsar, Yue Wang, Louisa Alim, Andrew N. Wilkinson, Michelle A. Tran, Gowri Irgam, Sharat Atluri, Kiefer Wong, Jae-Jun Shim, Siddharth Adityan, Ju-Seog Lee, Willem W. Overwijk, Raymond Steptoe, Da Yang, Sherry Y. Wu
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Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-09-13 Zehua Sun, Xiaojie Chu, Cynthia Adams, Tatiana V. Ilina, Michel Guerrero, Guowu Lin, Chuan Chen, Dontcho Jelev, Rieko Ishima, Wei Li, John W. Mellors, Guillermo Calero, Dimiter S. Dimitrov
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Oncolytic myxoma virus is effective in murine models of triple negative breast cancer despite poor rates of infection Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-09-01 Raquela J. Thomas, Mee Y. Bartee, Miriam Valenzuela-Cardenas, Eric Bartee
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Transgenic viral expression of PH-20, IL-12, and sPD1-Fc enhances immune cell infiltration and anti-tumor efficacy of an oncolytic virus Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-31 Soon-Oh Hong, Joonsung Kim, Sungmin Lee, Jaeil Shin, Hwanjun Choi, Eunjin Lee, Hyesoo Kang, Hyesun Lee, Soondong Lee, Naeun Yun, Jiwon An, Heonsik Choi, Hyeree Kim, Wonseok Kang, Yeup Yoon, Sujeong Kim
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Smoking induces WEE1 expression to promote docetaxel resistance in esophageal adenocarcinoma Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-28 Md Obaidul Islam, Krishnapriya Thangaretnam, Heng Lu, Dunfa Peng, Mohammed Soutto, Wael El-Rifai, Silvia Giordano, Yuguang Ban, Xi Chen, Daniel Bilbao, Alejandro V. Villarino, Stephan Schürer, Peter J. Hosein, Zheng Chen
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Enhancing the effectiveness of γδ T cells by mRNA transfection of chimeric antigen receptors or bispecific T cell engagers Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-24 John Anderson, Marta Barisa
Abstract not available
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A new strategy for treating colorectal cancer: Regulating the influence of intestinal flora and oncolytic virus on interferon Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-24 Jia Yi, Peizhe Lin, Qingbo Li, Ao Zhang, Xianbin Kong
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Claudin18.2 bispecific T cell engager armed oncolytic virus enhances antitumor effects against pancreatic cancer Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-24 Shiyu Liu, Fan Li, Li Deng, Qiongqiong Ma, Wenyi Lu, Zhuoqian Zhao, Huanzhen Liu, Yixuan Zhou, Manli Hu, Hui Wang, Yingbin Yan, Mingfeng Zhao, Hongkai Zhang, Mingjuan Du
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Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-20 Chiara F. Magnani, Renier Myburgh, Silvan Brunn, Morgane Chambovey, Marianna Ponzo, Laura Volta, Francesco Manfredi, Christian Pellegrino, Steve Pascolo, Csaba Miskey, Nicolás Sandoval-Villegas, Zoltán Ivics, Judith A. Shizuru, Dario Neri, Markus G. Manz
Abstract not available
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Hypoxia-regulated secretion of IL-12 enhances antitumor activity and safety of CD19 CAR-T cells in the treatment of DLBCL Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-18 Wenping Zhou, Jinxin Miao, Zhenguo Cheng, Zhimin Wang, Jianyao Wang, Haoran Guo, Pengju Wang, Shuangshuang Lu, Lingling Si, Zhongxian Zhang, Louisa Chard Dunmall, Yanyan Liu, Nicholas R. Lemoine, Yaohe Wang
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JNTX-101, a novel albumin-encapsulated gemcitabine prodrug, is efficacious and operates via caveolin-1-mediated endocytosis Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-18 Tiantian Cui, Sergio Corrales-Guerrero, Veronica Castro-Aceituno, Sindhu Nair, Daniel C. Maneval, Curtis Monnig, Patrick Kearney, Sam Ellis, Nicholas Raheja, Neil Raheja, Terence M. Williams
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Therapeutic potential of gene therapy for gastrointestinal diseases: Advancements and future perspectives Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-18 Ning-ning Yue, Hao-ming Xu, Jing Xu, Min-zheng Zhu, Yuan Zhang, Cheng-Mei Tian, Yu-qiang Nie, Jun Yao, Yu-jie Liang, De-feng Li, Li-sheng Wang
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Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-18 Amos Hong Pheng Loh, Min Thura, Abhishek Gupta, Sheng Hui Tan, Kelvin Kam Yew Kuan, Koon Hwee Ang, Khurshid Merchant, Kenneth Tou En Chang, Hui Yi Yon, Yong Chen, Mathew Hern Wang Cheng, Arjandas Mahadev, Matthew Chau Hsien Ng, Michaela Su-Fern Seng, Prasad Iyer, Pei Ling Chia, Shui Yen Soh, Qi Zeng
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Interleukin-6-controlled, mesenchymal stem cell-based sodium/iodide symporter gene therapy improves survival of glioblastoma-bearing mice Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-15 Carolin Kitzberger, Khuram Shehzad, Volker Morath, Rebekka Spellerberg, Julius Ranke, Katja Steiger, Roland E. Kälin, Gabriele Multhoff, Matthias Eiber, Franz Schilling, Rainer Glass, Wolfgang A. Weber, Ernst Wagner, Peter J. Nelson, Christine Spitzweg
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Endogenous H3.3K27M derived peptide restricted to HLA-A∗02:01 is insufficient for immune-targeting in diffuse midline glioma Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-15 Stacie S. Wang, Kirti Pandey, Katherine A. Watson, Rebecca C. Abbott, Nicole A. Mifsud, Fiona M. Gracey, Sri H. Ramarathinam, Ryan S. Cross, Anthony W. Purcell, Misty R. Jenkins
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Oncolytic virotherapy with chimeric VSV-NDV synergistically supports RIG-I-dependent checkpoint inhibitor immunotherapy Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-08-05 Janina Marek, Lorenz Hanesch, Teresa Krabbe, Nadia El Khawanky, Simon Heidegger, Jennifer Altomonte
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The quest for effective immunotherapies against malignant peripheral nerve sheath tumors: Is there hope? Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-07-31 Siddhi N. Paudel, Brian Hutzen, Timothy P. Cripe
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Nanobody-derived bispecific CAR-T cell therapy enhances the anti-tumor efficacy of T cell lymphoma treatment Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-07-28 Baijin Xia, Keming Lin, Xuemei Wang, FeiLi Chen, Mo Zhou, Yuzhuang Li, Yingtong Lin, Yidan Qiao, Rong Li, Wanying Zhang, Xin He, Fan Zou, Linghua Li, Lijuan Lu, Cancan Chen, WenYu Li, Hui Zhang, Bingfeng Liu
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Oncolytic virotherapy with intratumoral injection of vaccinia virus TG6002 and 5-fluorocytosine administration in dogs with malignant tumors Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-07-20 Jérémy Béguin, Eve Laloy, Sandrine Cochin, Murielle Gantzer, Isabelle Farine, Christelle Pichon, Baptiste Moreau, Johann Foloppe, Jean-Marc Balloul, Christelle Machon, Jérôme Guitton, Dominique Tierny, Bernard Klonjkowski, Eric Quéméneur, Christelle Maurey, Philippe Erbs
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Neoadjuvant use of oncolytic herpes virus G47Δ prevents local recurrence after insufficient resection in tongue cancer models Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-07-19 Kosuke Inoue, Hirotaka Ito, Miwako Iwai, Minoru Tanaka, Yoshiyuki Mori, Tomoki Todo
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Current advances of liquid biopsies in prostate cancer: Molecular biomarkers Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-07-19 Murad Alahdal, Roshane A. Perera, Marcio Covas Moschovas, Vipul Patel, Ranjan J. Perera
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Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-07-19 Chiara F. Magnani, Renier Myburgh, Silvan Brunn, Morgane Chambovey, Marianna Ponzo, Laura Volta, Francesco Manfredi, Christian Pellegrino, Steve Pascolo, Csaba Miskey, Zoltán Ivics, Judith A. Shizuru, Dario Neri, Markus G. Manz
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Development of a bicistronic anti-CD19/CD20 CAR construct including abrogation of unexpected nucleic acid sequence deletions Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-07-19 Norris Lam, Richard Finney, Shicheng Yang, Stephanie Choi, Xiaolin Wu, Lauren Cutmore, Jorge Andrade, Lei Huang, Christina Amatya, Margaret Cam, James N. Kochenderfer
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Oncolytic virus-driven immune remodeling revealed in mouse medulloblastomas at single cell resolution Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-07-19 Jack Hedberg, Adam Studebaker, Luke Smith, Chun-Yu Chen, Jesse J. Westfall, Maren Cam, Amy Gross, Ilse Hernandez-Aguirre, Alexia Martin, Doyeon Kim, Ravi Dhital, Yeaseul Kim, Ryan D. Roberts, Timothy P. Cripe, Elaine R. Mardis, Kevin A. Cassady, Jeffrey Leonard, Katherine E. Miller
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Dynamic fine-tuning of CAR-T cell therapy Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-06-29 Pierre V.M. Trehin, Geisler Muñoz-Guamuro, Wilfried Weber
Abstract not available
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Potent and selective eradication of tumor cells by an EpCAM-targeted Ras-degrading enzyme Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-06-27 Valentina Palacio-Castañeda, Bas van de Crommert, Elke Verploegen, Mike Overeem, Jenny van Oostrum, Wouter P.R. Verdurmen
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PTEN potentiation of oncolytic HSV therapy for glioblastoma Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-06-02 Christian Migliarese, Hiroaki Wakimoto
Abstract not available
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Radiovirotherapy at twenty Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-05-26 David Dingli
Abstract not available
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Trap and ambush therapy using sequential primary and tumor escape-selective oncolytic viruses Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-05-22 Mason J. Webb, Timothy Kottke, Benjamin L. Kendall, Jack Swanson, Chisom Uzendu, Jason Tonne, Jill Thompson, Muriel Metko, Madelyn Moore, Mitesh Borad, Lewis Roberts, Rosa M. Diaz, Michael Olin, Antonella Borgatti, Richard Vile
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Enhancing the effectiveness of γδ T cells by mRNA transfection of chimeric antigen receptors or bispecific T cell engagers Mol. Ther. Oncolytics (IF 5.7) Pub Date : 2023-05-22 Scott A. Becker, Brian G. Petrich, Bing Yu, Kristopher A. Knight, Harrison C. Brown, Sunil S. Raikar, Christopher B. Doering, H. Trent Spencer