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Efficacy and Safety of Once-Daily Vilanterol/Fluticasone Furoate MDI in Persistent Asthma: Phase 3 OD-INHALE study J. Asthma (IF 1.9) Pub Date : 2024-03-15 Avdhesh Kumar, Manish Kumar Jain, Vijaykumar Bhagwan Barge, Raghumanda Sunil Kumar, Neeraj Gupta, Harendra Yadav, Amitava Pal, Vivek Eknath Redkar, Asish Mondal, Rahul Kumar Rathore, Pavankumar Daultani, Ashok Jaiswal, Ravi T. Mehta
Introduction: Once-daily inhalers have been shown to improve adherence leading to lesser discontinuation compared to twice- or thrice-daily inhalers in management of asthma. Combination of Vilanter...
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Bacterial antigens and asthma: a comparative study of common respiratory pathogenic bacteria J. Asthma (IF 1.9) Pub Date : 2024-03-13 Jie Pang, Yifan Shi, Dan Peng, Lele Cui, Yingjie Xu, Wenjing Wang, Yue Hu, Yiran Yang, Jingjing Wang, Xiaofeng Qin, Yue Zhang, Hao Meng, Dan Wang, Ge Bai, Huihui Yuan, Jie Liu, Zhe Lv, Yan Li, Ye Cui, Wenjun Wang, Kewu Huang, Chris J Corrigan, Wei Wang, Yan Chen, Sun Ying
In a previous study we have shown that, in the presence of interleukin (IL)-33, repeated, per-nasal challenge of murine airways with Streptococcus pneumoniae (S. pneumoniae) organisms induces human...
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Cost-effectiveness of mepolizumab for severe eosinophilic asthma in China J. Asthma (IF 1.9) Pub Date : 2024-03-12 Xiong Chaogang, An Mengna, Wang Zhen, Li Ying, Gu Xin, Zhang Xin, Zhang Shengjie, Zhao Yuan, Lei Qian, Ma Wenbin, Feng Weiyi
To evaluate the economic value of mepolizumab as an add-on therapy to the standard of care (SoC) for patients with severe eosinophilic asthma in China.A Markov model with three health conditions wa...
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ARE NIGHT-TIME RESPIRATORY SYMPTOMS ASSESSED BY ASTHMA CONTROL TEST AFFECTED BY COMORBIDITIES? J. Asthma (IF 1.9) Pub Date : 2024-03-06 Alida Benfante, Alessandra Tomasello, Chiara Caponetto, Salvatore Battaglia, Nicola Scichilone
Nocturnal symptoms are common in the asthmatic population, reflecting an exaggerated airway narrowing overnight due to several factors; it is questioned to what extent the awakenings documented in ...
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Cost-Utility Analysis of Prenatal Supplementation with Long-Chain n-3 Fatty Acids to Reduce the Incidence of Wheezing and Asthma in Neonates. J. Asthma (IF 1.9) Pub Date : 2024-03-01 jefferson Antonio buendia, Diana Guerrero-Patino, Andres Zuluaga
Published in Journal of Asthma (Just accepted, 2024)
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Reactance inversion in moderate to severe persistent asthma: low birth weight, prematurity effect, and bronchodilator response J. Asthma (IF 1.9) Pub Date : 2024-03-01 Ramiro González Vera Dr., Alberto Vidal Grell Dr., José A Castro-Rodríguez Dr., María A Palomino Montenegro Dra., Alejandra Méndez Yarur
Introduction Reactance Inversion (RI) has been associated with impaired peripheral airway function in persistent asthma. However, there is little to no data about the difference between asthmatic c...
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Screening Asthmatics for Atopic Status using the ALergy EXplorer (ALEX2) Macroarray J. Asthma (IF 1.9) Pub Date : 2024-02-28 Robert G Hamilton, Mark Holbreich, Charles Bronzert, Rebecca L Anderson, Nathan Schoettler, Carole Ober
Background: Screening asthma patients for atopy facilitates management. Since 2010, the core biomarker for screening asthma subjects for atopic status has been the qualitative Phadiatop. multi-aero...
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A Comprehensive Review of the Intersection Between Asthma and Depression J. Asthma (IF 1.9) Pub Date : 2024-02-28 Tahoora Abdul Nasir Surve, DhruviKumari D Sharma, Kiyan Ghani Khan, Neisha Ghanie, Riley Charanrak, Mouhammad Sharifa, Samreen Begum, Maria Jose Auz, Nozima Akbarova, Maneeth Mylavarapu
Objective To emphasize the necessity for increased research in this field, incorporating depression into the preventative, diagnostic, and therapeutic considerations for asthma. Additionally, we se...
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Identification of Two Hub Genes and miRNA‑mRNA Interactions in Chronic Obstructive Pulmonary Disease (COPD) Plasma J. Asthma (IF 1.9) Pub Date : 2024-02-27 Yuanyuan Qian, Yifei Li, Jiancheng Ji, Zhaojunli Wang
We aimed to identify hub genes in chronic obstructive pulmonary disease (COPD) plasma through the exploration of a putative miRNA–mRNA regulatory network.Three datasets (GSE24709, GSE102915, GSE136...
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Prevalence of aeroallergen sensitization in children in Northern China J. Asthma (IF 1.9) Pub Date : 2024-02-26 Sainan Bian, Wenjing Zhu, Kai Guan, Li Sha
This study aimed to analyze the sensitization rate of different aeroallergens in children of different age, sex, and disease groups, describe the changing trend of different aeroallergens in differ...
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N-Acetyl Cysteine Augments Adipose Tissue-Derived Stem Cell Efficacy on Inflammatory Markers and Regulatory T Cell System Balance in an Allergic Asthma Model J. Asthma (IF 1.9) Pub Date : 2024-02-20 Maryam Radan, Farhad Abol Nejadian, Vahid Bayati, Ali Asghar Hemmati, Khojasteh Hoseinynejad, Seyyed Ali Mard
Background Allergic asthma is a destructive inflammatory process in the respiratory system. The anti-inflammatory and antioxidant effects of N-acetylcysteine (NAC) have been reported in patients wi...
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Clinical characteristics of children with asthma exacerbations: A cross-sectional descriptive study J. Asthma (IF 1.9) Pub Date : 2024-02-20 Ezgi Cay, Veysel Karakulak, Ahmet Sezer, Huseyin Baspinar, Nilgun Bahar, Busra Hatice Fidan, Mahir Serbes, Sevcan Bilen, Sevinc Puren Yucel, Dilek Ozcan, Derya Ufuk Altintas
Aim: In this cross-sectional descriptive study, we aimed to determine the clinical characteristics of children admitted to a tertiary hospital with asthma exacerbations in a city in southern Turkey...
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Impact of the pulmonary ventilation function on the prognosis of suspected asthma patients: A retrospective observational study J. Asthma (IF 1.9) Pub Date : 2024-02-22 Ming-juan Zhou, Li Fu, Wen-qian Lin, Zhen-ni Wu, Fang Nie, Chu-yin Ye, Wen-han Zhao
Asthma is a common chronic respiratory diseases, and the relationship between pulmonary ventilation function and the prognosis of patients with suspected asthma is not well understood. This study a...
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Relationship between serum IgA levels and low percentage forced expiratory volume in the first second in asthma J. Asthma (IF 1.9) Pub Date : 2024-02-20 Sahoko Imoto, Maho Suzukawa, Kazufumi Takada, Shizuka Watanabe, Asari Isao, Takahide Nagase, Hiroyuki Nagase, Ken Ohta
Immunoglobulin A (IgA) is suggested to have pathogenic effects in respiratory inflammatory diseases, including asthma. We aimed to analyze the relationship between serum IgA, and clinical indicator...
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Evaluation of the quality and content of YouTube videos as an educational resource in developing patients' inhaler use skills J. Asthma (IF 1.9) Pub Date : 2024-02-15 Ozlem Canbolat, Ayse Buket DoganAktas, Gulhayat Sipal, Kokturk Nurdan
Background: YouTube has educational videos on inhalers. However, their content and quality are not adequately known.Objectives: This study investigated the quality and content of educational YouTub...
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The Turkish Adaptation of The Adherence to Asthma Medication Questionnaire J. Asthma (IF 1.9) Pub Date : 2024-02-15 Döndü Erdoğan İnan, Ülkü Polat
Background: This study was conducted to adapt the Adherence to Asthma Medication Questionnaire (AAMQ-13) into Turkish.Methods: The research was conducted in the pulmonology outpatient clinic of a s...
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Toll-like receptor 4 Mediated Autophagy regulates Airway Smooth Muscle Cells behavior J. Asthma (IF 1.9) Pub Date : 2024-02-13 LiXia Hou, HuiQing Zuo, Bo Xiao, Dong Yao
Objectives: Airway remodeling, a prominent feature of asthma, involves aberrant proliferation, apoptosis, and migration of airway smooth muscle cells (ASMCs). Toll-like receptors (TLRs) are implica...
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The relationships between Physical activity and asthma control and Body Mass Index (BMI) in patients with asthma J. Asthma (IF 1.9) Pub Date : 2024-02-08 Bonny Rockette-Wagner, Juan P. Wisnivesky, Fernando Holguin, Jyoti Ankam, Arushi Arora, Emily Federmann, Vongphone Smith, Alex D. Federman, Molly B. Conroy
Asthma is one of the most common chronic conditions in developed countries. We examined whether physical activity (PA) is related to asthma control and body mass index (BMI) in asthma patients.Cros...
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Machine learning-based prediction of in-hospital mortality in patients with pneumonic chronic obstructive pulmonary disease exacerbations J. Asthma (IF 1.9) Pub Date : 2024-02-08 Lin Yu, Xia Ruan, Wenbo Huang, Na Huang, Jun Zeng, Jie He, Rong He, Kai Yang
While linear regression and LASSO models have been established for predicting in-hospital mortality, there is currently no validated clinical prediction algorithm to predict in-hospital mortality f...
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Tropical high altitude and severe asthma in adults: house dust mite sensitization and phenotypic distribution J. Asthma (IF 1.9) Pub Date : 2024-02-08 Carlos A. Torres-Duque, Abraham Alí-Munive, Diego Severiche-Bueno, Mauricio Durán-Silva, Carlos E. Aguirre-Franco, Angélica González-Florez, María José Pareja-Zabala, Libardo Jiménez-Maldonado, Mauricio Gonzalez-Garcia
There is a lack of information on house dust mite (HDM) sensitization and phenotype distribution in patients with severe asthma (SA) living permanently at high-altitude (HA) in tropical regions, wh...
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Safety and efficacy of benralizumab in elderly subjects with severe asthma J. Asthma (IF 1.9) Pub Date : 2024-02-08 Marcela Valverde-Monge, Remedios Cárdenas, Ismael García-Moguel, Ana Rosado, Mar Gandolfo-Cano, Teresa Robledo Echarren, María del Mar Moro-Moro, María del Mar Reaño Martos, Rafael Pineda-Pineda, Cristina Martin-Arriscado Arroba, Javier Domínguez-Ortega, AIRE Group
The prevalence of asthma in adults >65 years old is approximately 12–14%, and 10% have severe asthma. A higher mortality rate is observed in subjects with asthma >65 years old and especially >80 ye...
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Adherence to the asthma pathway, including pre-triage bronchodilator history, reduces hospitalizations J. Asthma (IF 1.9) Pub Date : 2024-02-08 Suttipong Ittiporn, Kanlaya Prajongdee
Objective: To determine if adherence to an asthma treatment pathway is associated with a decrease in hospitalizations.Methods: A prospective cohort design was conducted of Thai children aged 2–15 y...
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Efficacy of Bhramari pranayama and Om chanting on asthma control, quality of life, and airway inflammation in asthmatic children: an open-label randomized controlled trial J. Asthma (IF 1.9) Pub Date : 2024-02-08 Rashmi Yadav, Sushil Kumar Kabra, Raj Kumar Yadav, Arnab Nandy, Ashish Datt Upadhyay, Kana Ram Jat, Rakesh Lodha
To explore the efficacy of combination of Bhramari pranayama and om chanting as an adjunct to standard pharmacological treatment on asthma control, quality of life, pulmonary function, and airway i...
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Activation of Notch1-GATA3 pathway in asthma bronchial epithelial cells induced by acute PM2.5 exposure and the potential protective role of microRNA-139-5p J. Asthma (IF 1.9) Pub Date : 2024-02-12 Junjun Huang, Yan Hu, Yunxia Wang, Zhou Jin
PM2.5 is closed linked to asthma exacerbation. The Notch1 pathway acts as an important pathway, ultimately inducing T-helper cells that express GATA3 and its corresponding Th2 cytokines. The regula...
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Emergency Management and Asthma Risk in Young Medicaid-Enrolled Children with Recurrent Wheeze J. Asthma (IF 1.9) Pub Date : 2024-02-07 Isabel J. Hardee, Isabella Zaniletti, Melisa S. Tanverdi, Andrew H. Liu, Rakesh D. Mistry, Nidhya Navanandan
To describe clinical characteristics of young children presenting to the emergency department (ED) for early recurrent wheeze, and determine factors associated with subsequent persistent wheeze and...
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Digitally monitored inhaled therapy: A ‘Smart’ way to manage severe asthma? J. Asthma (IF 1.9) Pub Date : 2024-02-07 Dominic L Sykes, Yee Yong See, Evon C Y Chow, Michael G Crooks, Helena Cummings, Mandy Robinson, Karen Watkins, Joanne Thompson, Kylie Overton, Charlotte Riches, Shoaib Faruqi
One of the fundamental challenges of managing patients with severe asthma is treatment adherence, particularly with inhaled corticosteroids. Adherence is difficult to measure objectively and poor a...
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Effect of stearoyl-coenzyme a desaturase 1 (SCD1) on the function of mast cells J. Asthma (IF 1.9) Pub Date : 2024-02-05 Xiuqing Zhang, Aiguo Li, Yifan Zhu, Feng Liu, Deyu Zhao, Heng Tang, Changdi Xu
Background: The prevalence of childhood asthma and obesity is increasing, while obesity increases the risk and severity of asthma. Lipid metabolism has been considered as an important factor in the...
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Evaluating the implementation of a community health worker-delivered intervention integrating asthma care in West Philadelphia public schools J. Asthma (IF 1.9) Pub Date : 2024-02-01 Kayla Clark, Elizabeth Messineo, Tyra Bryant-Stephens, Angela Song, Darby Marx, Adina Lieberman, Rinad S. Beidas, Courtney Benjamin Wolk
Schools are an important setting because students spend much of their time in school and engage in physical activity during the school day that could exacerbate asthma symptoms. Our objective is to...
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Near fatal asthma in a case of allergic bronchopulmonary aspergillosis (ABPA) treated with ECMO J. Asthma (IF 1.9) Pub Date : 2024-01-31 Shili Zhong, Zhengbin Wu, Chunyan Chen, Hong Xiao, Zhen Wang
Fatal asthma is a rapidly progressing and highly fatal form of asthma. Mechanical ventilation, although necessary for respiratory support, can exacerbate the condition and lead to ventilator-associ...
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Rapidly progressive mucus plugs in allergic bronchopulmonary mycosis J. Asthma (IF 1.9) Pub Date : 2024-01-31 Osamu Miyazaki,, Akira Igarashi,, Kento Sato,, Sumito Inoue,, Ryuto Yokoyama,, Masaki Nakane,, Sahoko Kodama,, Ryo Hasegawa,, Shigeharu Ueki,, Takashi Yaguchi,, Akira Watanabe,, Masafumi Watanabe
Allergic bronchopulmonary mycosis (ABPM) is a chronic airway disease characterized by the presence of fungi that trigger allergic reactions and airway obstruction. Here, we present a unique case of...
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Atomized inhalation of Icaritin reduces airway inflammation and remodeling in asthmatic mice J. Asthma (IF 1.9) Pub Date : 2024-01-31 Yintong He, Jian Cui, Bo Xiao, Lixia Hou, Zhimei Li, Huiqin Zuo, Yutong He, Dong Yao
Asthma is a disease characterized by airway hyperresponsiveness and airway inflammation. Icaritin (ICT) is a plant hormone with various pharmacological activities such as anti-inflammatory, immune ...
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Insight into the role of mitochondrion-related gene anchor signature in mitochondrial dysfunction of neutrophilic asthma J. Asthma (IF 1.9) Pub Date : 2024-01-31 Lu Lin, Zeng-hua Liao, Chao-qian Li
At present, targeting molecular-pharmacological therapy is still difficult in neutrophilic asthma. The investigation aims to identify and validate mitochondrion-related gene signatures for diagnosi...
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Efficacy of bronchial thermoplasty in a patient panel with uncontrolled severe persistent asthma J. Asthma (IF 1.9) Pub Date : 2024-01-31 Antonios Zikos, Marvin Balaan, Emily Hobart, Sandeep Bansal, Rihab Saeed, Tariq Cheema, Deborah Gentile
Bronchial thermoplasty (BT) is an approved procedure to manage uncontrolled severe persistent asthma. Many insurance providers are reluctant to pay for BT without proven benefit among their specifi...
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Biologics for asthma and risk of pneumonia J. Asthma (IF 1.9) Pub Date : 2024-01-31 Maria Gabriella Matera, Josuel Ora, Luigino Calzetta, Paola Rogliani, Mario Cazzola
Modification of the immune system with biologics raises theoretical concerns about the risk of infections but it is still unclear whether currently routinely used biologics in severe asthma may fac...
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There is no association between serum endotoxin levels and inflammation in asthma J. Asthma (IF 1.9) Pub Date : 2024-01-30 Ozlem Candan, Tayfur Toptas, Semra Demir, Fusun Erdenen
Endotoxin, in lipopolysaccharide structure (LPS), is the main component of the outer membrane of gram negative bacteria. LPS levels were associated with inflammatory disease. Asthma is a chronic in...
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Assessment of acute asthma in children: Do parents and healthcare providers speak the same language? J. Asthma (IF 1.9) Pub Date : 2024-01-24 J.V. Markwat, J. vanLeeuwen, A. W. A. Kamps
ObjectiveEducation and self-management plans enhance parents' self-efficacy in managing their child's asthma symptoms. By understanding how parents recognize and interpret acute asthma symptoms, we...
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Decoding the Genetic Landscape of Allergic Rhinitis: A Comprehensive Network Analysis Revealing Key Genes and Potential Therapeutic Targets J. Asthma (IF 1.9) Pub Date : 2024-01-24 Chile Yuan, Xiaohong Lin, Ruosha Liao
Allergic Rhinitis (AR), an inflammatory affliction impacting the upper respiratory tract, has been registering a substantial surge in incidence across the globe.We embarked on examination of differ...
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Anti-IL-5 and anti-IL-5R biologics for severe asthma. Are there any differences in their effects? J. Asthma (IF 1.9) Pub Date : 2024-01-24 P Granda, E Villamañán, C Carpio, D Laorden, S Quirce, R Álvarez-Sala, on behalf of the NEUMO Study Group
The aim of this retrospective multicentre study is to describe the clinical characteristics of patients diagnosed with severe eosinophilic asthma receiving anti-IL-5/anti-IL-5Rα therapies and to co...
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Promoting Knowledge of Metered Dose Inhaler (MDI) Usage Among Pharmacy Professional Students through A Mobile App J. Asthma (IF 1.9) Pub Date : 2024-01-18 Muhammad Thesa Ghozali, Tasya Aulia Mutiara
Introduction:Efficient asthma management necessitates optimal usage of metered-dose inhalers (MDIs). As future health professionals, pharmacy students are pivotal in disseminating accurate methodol...
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Mepolizumab in children and adolescents with severe eosinophilic asthma not eligible for Omalizumab: a single centre experience J. Asthma (IF 1.9) Pub Date : 2024-01-19 Y T Lim, T C Williams, R J Langley, E Weir
Background Mepolizumab is an anti-interleukin-5 monoclonal antibody shown to reduce asthma exacerbations in adults and adolescents with severe eosinophilic asthma.Aim To assess the impact of mepoli...
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The Effect of Online Peer and Adult Education Given to Adolescents with Allergic Asthma on Their Quality of Life, Self-Efficacy, Anxiety, and Disease Knowledge and Management: A Randomized Controlled Study J. Asthma (IF 1.9) Pub Date : 2024-01-16 Pelin Karatas, Husniye Calisir
Objective: To examine the effect of interactive online education given by peers or adults on anxiety, self-efficacy, quality of life, disease knowledge and management in adolescents with allergic a...
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ASTHMAXcel PRO Patient Satisfaction and Usability Field Testing J. Asthma (IF 1.9) Pub Date : 2024-01-16 Nicole Wedel, Nicole Zinger, Anjani K Singh, Savneet Kaur, Obumneme Njeze, Emine Cosar, Wenzhu Mowrey, Samuel Green, Marina Reznik, John Feldman, Zhaoyuan Su, Asif Ansari, Carol Elrington, Manuja Mathur, Kai Zheng, Sunit P Jariwala
Published in Journal of Asthma (Just accepted, 2024)
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ABPA and AFRS: Addressing Prevalence, Early Diagnosis, Allergens, and Occupational Concerns J. Asthma (IF 1.9) Pub Date : 2024-01-12 Anu Priya Minhas, Santasabuj Das
ObjectiveThis study aimed to comprehensively investigate the prevalence of ABPA and AFRS, scrutinize existing diagnostic criteria and immunoassays, pinpoint their limitations, highlight ABPA as an ...
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Associations of Personal Urinary Volatile Organic Compounds and Lung Function in Children J. Asthma (IF 1.9) Pub Date : 2024-01-10 Dawon Park, Eun Kyo Ha, Haeri Jung, Ju Hee Kim, Jeewon Shin, Mi Ae Kim, Youn Ho Shin, Hye Mi Jee, Man Yong Han
BackgroundWe investigated the correlation between urine VOC metabolites and airway function in children exposed to anthropogenic volatile organic compounds (VOCs), notable pollutants impacting resp...
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Aquatic exercise for people with asthma: a systematic review with meta-analysis of randomized controlled trials J. Asthma (IF 1.9) Pub Date : 2024-01-10 Franciele Angelo Deus, Cecylia Leiber Fernandes e Castro, Vinícius Cunha Oliveira, Pedro Henrique Scheidt Figueiredo, Henrique Silveira Costa, Diego Mendes Xavier, Wellington Fabiano Gomes, Vanessa Pereira Lima
Introduction Aquatic exercises are among the types of exercise most tolerated by people with asthma. Therefore, the objective of this study was to synthesize the evidence on the effects of aquatic ...
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Factors associated with emergency department visits for asthma resulting in hospital admission— United States, 2020 J. Asthma (IF 1.9) Pub Date : 2024-01-09 Xiaoting Qin, Cynthia A. Pate, Hatice S. Zahran
ObjectiveTo identify risk factors associated with hospital admission following an ED visit for asthma at the time of discharge among U.S. children and adults.MethodsAsthma emergency department visi...
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Impact of pollen season and viral disease COVID-19 on respiratory function of the adult population in eastern Slovakia: analysis of spirometric data and results of a questionnaire survey J. Asthma (IF 1.9) Pub Date : 2024-01-09 Gabriela Harvanová, Alexander Csanády, Silvia Duranková
Asthma is a chronic heterogeneous disease with characteristic symptoms, but with proper treatment the patient can lead a full life. In patients with allergic asthma, symptoms appear after irritatio...
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Association between PRKG1 Gene and Gene-Environment Interactions with Pediatric Asthma J. Asthma (IF 1.9) Pub Date : 2024-01-09 Jun Liu, Bing Wei, Yuxuan Zhang, Yuan You, Yanjie Zhi
To investigate the relationship between single nucleotide polymorphisms (SNPs) of cGMP-dependent protein kinase I (PRKG1) gene and gene-environment interactions with bronchial asthma in children.10...
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Prevalence and Characteristics in Long COVID among Adults with Asthma in the United States J. Asthma (IF 1.9) Pub Date : 2024-01-08 Chun-Tse Hung, Yu-Chien Hung, Chi-Won Suk
The purpose of this study was to assess: (1) the prevalence of long COVID by asthma status, and (2) the characteristics associated with developing long COVID among adults with asthma in the United ...
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Possible role of HE4 level elevation in the pathogenesis of TH2-high asthma J. Asthma (IF 1.9) Pub Date : 2024-01-09 Kan Zhang, Yu Cao, Hexuan Tang, Dang Lin
As a heterogeneous disease, asthma is characterized by airway hyperresponsiveness, airway inflammation, and airway mucus hypersecretion. According to the pathological changes, symptoms, preventive ...
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Pretreatment asthma control test score as a predictive score for clinical remission after bronchial thermoplasty in younger patients with severe asthma and preserved lung function J. Asthma (IF 1.9) Pub Date : 2024-01-01 Fumihiro Kashizaki, Kenji Konishi, Hao Chen, Arihito Tanaka, Atsushi Miyasaka, Shunsuke Okazaki, Chihiro Yamada, Nanami Tsuchiya, Kentaro Yumoto, Harumi Koizumi, Kenichi Takahashi, Takeshi Kaneko
Bronchial thermoplasty (BT) decreases the incidence of asthma exacerbations, emergency room visits, and hospitalizations among patients with severe asthma. Predictors of BT effectiveness remain unc...
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Correlation between Changes in Serum YKL-40, LXRs, PPM1A, and TGF-β1 Levels and Airway Remodeling and Lung Function in Patients with Bronchial Asthma J. Asthma (IF 1.9) Pub Date : 2024-01-02 Ying Zhu, Bowen Huang, Guang Jiang
Objective: This study investigates the correlation between serum levels of YKL-40, LXRs, PPM1A, and TGF-β1 and airway remodeling and lung function in bronchial asthma patients.Methods: The study in...
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U-shaped association between 25-Hydroxyvitamin D Concentration and the prevalence of asthma in the overweight and obese U.S. population J. Asthma (IF 1.9) Pub Date : 2024-01-02 XueLi Shi, ZiJia Yan, Jing Xue, CongLi Tian
vitamin D supplementation has shown promise in averting asthma. However, the association between 25(OH)D levels and asthma prevention in various demographic groups remains inconclusive. Here, we ex...
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Exploring the diversity of CFTR gene mutations in cystic fibrosis individuals of South Asia J. Asthma (IF 1.9) Pub Date : 2023-12-28 Hassan Rafique, Anum Safdar, Muhammad Usman Ghani, Ali Akbar, Farheena Iqbal Awan, Zartashay Naeem, Ali Amar, Mudassar Fareed Awan, Syed Wajahat Ullah, Rehan Sadiq Shaikh
Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the CFTR gene. This study aimed to identify the spectrum of CFTR variants reported in individuals with CF from South A...
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Doxofylline as a steroid-sparing treatment in Mexican children with asthma J. Asthma (IF 1.9) Pub Date : 2023-12-28 Sandra Nora González-Díaz, Ignacio J. Ansotegui, Carlos Macouzet-Sánchez, Natalhie Acuña-Ortega, Carlos de la Cruz-de la Cruz
The aim of this pilot study was to assess the efficacy of doxofylline as an ICS-sparing agent in the treatment of Mexican children with asthma.10-week, open-label, crossover, pilot study, we examin...
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Assessment of lifestyle and coping strategies among asthmatic patients during the Covid-19 crisis J. Asthma (IF 1.9) Pub Date : 2023-12-29 Eshrak Hashem, Faten Kandil, Fatmah Alsharif, Loujain Sharif, Asmaa Khaled
COVID-19 can cause an asthma attack by triggering asthma symptoms, such as wheezing, chest tightness, and difficulty breathing, which are distressing for patients and can cause anxiety. Additionall...
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Application of Different Counseling Strategies for Better Adult Asthma Control J. Asthma (IF 1.9) Pub Date : 2023-12-28 Basma M.E. Mohamed, Nabila laz, Haitham Saeed, Saleh Alghamdi, Mohamed AbdElrahman, Mohamed E.A. Abdelrahim, Hoda Rabea
Patients with asthma find it difficult to use their pressurized metered dose inhalers (pMDI) correctly. Several counseling methods are available to teach the patients how to use their inhaler devic...
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Global Influence of Dupilumab on Quality of Life in a Severe Asthma Patient with T2 Multimorbidities: A Case Report on Atopic Dermatitis, Chronic Rhinosinusitis with Nasal Polyposis, and Eosinophilic Esophagitis J. Asthma (IF 1.9) Pub Date : 2023-12-28 Monica Colque-Bayona, Natalia Hernández-Cano, Margarita Tomás-Pérez, Teresa Caballero, Santiago Quirce, Javier Domínguez-Ortega
Interleukin (IL)-4 and IL-13 are considered key drivers of type 2 inflammatory diseases. Dupilumab is a fully human monoclonal antibody that blocks the shared receptor component for IL-4 and IL-13,...
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Patient-reported outcome measures in severe asthma: an expert consensus J. Asthma (IF 1.9) Pub Date : 2023-12-26 Eva Martínez-Moragón, Ignacio Antepara Ercoreca, María Muñoz García, on behalf of the PROs-SA group of experts, Francisco Casas Maldonado, Marta Calvín Lamas, Eusebi Chiner Vives, Carlos Crespo Diz, David Díaz-Pérez, Ibon Eguiluz Gracia, Sara García Gil, Ruperto González-Pérez, Alicia Habernau Mena, Tamara Hermida Valverde, Sònia Jornet Montaña, Valentín López-Carrasco, Icíar Martínez López, Vicente
The study aimed to reach a consensus on the most relevant patient-reported outcomes (PROs), the corresponding measures (PROMs), and measurement frequency during severe asthma patient follow-up.Two ...
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Economic Evidence Supports the Cost Savings of Sputum Eosinophil Counts to guide the treatment of pediatrics patients with Persistent Asthma: Implications for Clinical Practice Guidelines in Middle-Income Countries. J. Asthma (IF 1.9) Pub Date : 2023-12-25 Jefferson Antonio Buendía, Diana Guerrero Patiño, Andrés Felipe ZuluagaSalazar
BACKGROUND: Tailoring asthma interventions based on biomarkers could substantially impact the high cost associated with asthma morbidity. For policymakers, the main concern is the economic impact o...