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Irisin/PGC-1α/FNDC5 pathway in Parkinson’s disease: truth under the throes Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-04-01 Naif H. Ali, Nourah Ahmad Alhamdan, Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Engy Elekhnawy, Gaber El-Saber Batiha
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Impact of glyphosate-based herbicide exposure through maternal milk on offspring’s antioxidant status, neurodevelopment, and behavior Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-11 Hammou Anarghou, Hafsa Malqui, Said Ihbour, Meriem Laaroussi, Oumaima Essaidi, Hamadi Fetoui, Mohamed Bouhrim, Mohamed Najimi, Fatiha Chigr
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Advances in microscopy characterization techniques for lipid nanocarriers in drug delivery: a comprehensive review Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-09 Mohamed J. Saadh, Mohammed Ali Shallan, Uday Abdul-Reda Hussein, Amjed Qasim Mohammed, Saeb Jasim Al-shuwaili, Mukaram Shikara, Ahmed Ali Ami, Noor Alhuda Mohammad Ali Khalil, Irfan Ahmad, Huda Hayder Abbas, Ahmed Elawady
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Protective effect of alpha‑lipoic acid against in utero cytarabine exposure-induced hepatotoxicity in rat female neonates Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-09 Ramanachary Namoju, Kavitha N Chilaka
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Protective effects of docosahexaenoic acid supplementation on cognitive dysfunction and hippocampal synaptic plasticity impairment induced by early postnatal PM2.5 exposure in young rats Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-09
Abstract PM2.5 exposure is a challenging environmental issue that is closely related to cognitive development impairment; however, currently, relevant means for prevention and treatment remain lacking. Herein, we determined the preventive effect of docosahexaenoic acid (DHA) supplementation on the neurodevelopmental toxicity induced by PM2.5 exposure. Neonatal rats were divided randomly into three
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A mechanistic review of the pharmacological potential of narirutin: a dietary flavonoid Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-08 Pratibha Pandey, Fahad Khan, Seema Ramniwas, Mohd Saeed, Irfan Ahmad
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Blockade of sympathetic ganglia improves vascular dysfunction in septic shock Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-08 Ana Maria Favero, Thiele Osvaldt Rosales, Karin Scheschowitsch, Muryel Carvalho Gonçalves, Patricia Oliveira Benedet, Regina Sordi, Geisson Marcos Nardi, Jamil Assreuy
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Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na+/K+-ATPase serving as a switch-on mechanism Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-07 Chi-Min Du, Wohn-Jenn Leu, Yi-Huei Jiang, She-Hung Chan, Ih-Sheng Chen, Hsun-Shuo Chang, Lih-Ching Hsu, Jui-Ling Hsu, Jih-Hwa Guh
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Ostarine blunts the effect of endurance training on submaximal endurance in rats Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-07 Veselin Vasilev, Nikolay Boyadjiev, Petar Hrischev, Fanka Gerginska, Slavi Delchev, Desislava Arabadzhiyska, Marina Komrakova, Kai O. Boeker, Arndt F. Schilling, Katerina Georgieva
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Ameliorative effects of topical ramelteon on imiquimod-induced psoriasiform inflammation in mice Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-06
Abstract Psoriasis is a long-lasting, immune-related inflammatory skin disease that affects 2–3% of the global population. It is distinguished by erythematous, silvery, and scaly patches. Ramelteon is a type of melatonin agonist that is used to treat insomnia. It has enhanced non-classical immunomodulatory and anti-inflammatory activities. The aim of the study is to assess the ameliorative effects
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Network pharmacology and experimental verification study on the mechanism of Hedyotis diffusa Willd in treating colorectal cancer Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-06 Xiya Yuan, Haifu Huang, Changhui Yu, Zhenhao Tang, Yaoxuan Li
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Hematological changes, oxidative stress assessment, and dysregulation of aquaporin-3 channel, prolactin, and oxytocin receptors in kidneys of lactating Wistar rats treated with monosodium glutamate Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-06 Nachamada Solomon Emmanuel, Tanko Yusuf, Ibrahim Gaya Bako, Ibrahim Samaila Malgwi, Ejike Daniel Eze, Zubairu Ali, Mohammed Aliyu
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An insight into thymidylate synthase inhibitor as anticancer agents: an explicative review Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-06 Aratrika Sen, Dipanjan Karati
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Enhanced upregulation of SIRT1 via pioglitazone and ligustrazine confers protection against ethanol-induced gastric ulcer in rats Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-05 Sara A. Mahmoud, Abeer Elkhoely, Elsayed K. El-Sayed, Amany A. E. Ahmed
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Thiacloprid impairs reproductive functions of male Wistar rats Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-05
Abstract Global male infertility correlated to the rise of endocrine-disrupting chemicals, including insecticides, has grown into a pressing problem. Thiacloprid is one of the most commonly used neonicotinoids that accounts for more than 25% of the global pesticide industry. However, its impact on the reproductive system and male fertility has not been fully elucidated. The object of this study was
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Long-term administration of omeprazole in mice: a study of behavior, inflammatory, and oxidative stress alterations with focus on central nervous system Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-04 Dulce Maria Nascimento Coelho, Dilailson Carlos Costa Júnior, Daniel Moreira Alves da Silva, Ana Carolina Benício Alves, Raquell de Castro Chaves, Manoela de Oliveira Rebouças, José Tiago Valentim, Andressa Alexandre de Oliveira, Iardja Stefane Lopes Sales, Lucas Antonio Duarte Nicolau, Francisca Cléa Florenço de Sousa
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Glycitein prevents reserpine-induced depression and associated comorbidities in mice: modulation of lipid peroxidation and TNF-α levels Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-02 Diksha, Lovedeep Singh
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Prescriptions of homeopathic remedies at the expense of the German statutory health insurance from 1985 to 2021: scientific, legal and pharmacoeconomic analysis Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-02 Hauke Leemhuis, Roland Seifert
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Curcumin inhibits the development of colorectal cancer via regulating the USP4/LAMP3 pathway Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-01 Hai Wei, Xianzhe Li, Fu Liu, Yuan Li, Bin Luo, Xin Huang, Hang Chen, Bo Wen, Pei Ma
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Targeted cancer treatment using folate-conjugated sponge-like ZIF-8 nanoparticles: a review Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-03-01 Mahsa Akbari Oryani, Shamim Nosrati, Hossein Javid, Ali Mehri, Alireza Hashemzadeh, Mehdi Karimi-Shahri
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Doxorubicin alters G-protein coupled receptor-mediated vasocontraction in rat coronary arteries Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-08 Caroline Lozahic, Helen Maddock, Mark Wheatley, Hardip Sandhu
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Enhancing treatment strategies for small bowel cancer: a clinical review of targeted therapy and immunotherapy approaches Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-08 Mehrshad Ebrahimpour, Hamidreza Hosseinzadeh, Farshad Abedi, Mohammad Moeini Nodeh, Abolghasem Allahyari, Amirhossein Sahebkar, Omid Arasteh
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Galbanic acid suppresses melanoma cell migration and invasion by reducing MMP activity and downregulating N-cadherin and fibronectin Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-07 Masoumeh Azad, Fatemehsadat Hosseini, Halimeh Hassanzade, Shahin Gharedaghi, Elahe Mahdipour, Fatemeh B. Rassouli, Khadijeh Jamialahmadi
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Network pharmacology and molecular docking–based investigation of monocyte locomotion inhibitory factor attenuates traumatic brain injury by regulating aquaporin 4 expression Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-07 Xinyu Li, Yulin Ma, Mengting Lv, Yuan Gao, Yuefan Zhang, Tiejun Li
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Hispidulin targets PTGS2 to improve cyclophosphamide-induced cystitis by suppressing NLRP3 inflammasome Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-07 Songlin Liu, Shuhang Li, Yuping Dong, Kun Qiao, Yang Zhao, Jianyong Yu
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Molecular mechanism of Spatholobi Caulis treatment for cholangiocarcinoma based on network pharmacology, molecular docking, and molecular dynamics simulation Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-07 Xu Chen, Bo Sun, Jia Zeng, Zhangtao Yu, Jie Liu, Zhiguo Tan, Yuhang Li, Chuang Peng
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The therapeutic value of Myrtus communis L.: an updated review Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-06 Ali Esmail Al-Snafi, John Oluwafemi Teibo, Hazem M. Shaheen, Opeyemi Abigail Akinfe, Titilade Kehinde Ayandeyi Teibo, Numonde Emieseimokumo, Mohamed M. Elfiky, Hayder M. Al-kuraishy, Ali I. Al-Garbeeb, Athanasios Alexiou, Marios Papadakis, Hitham Alaa Mohammed Mahana, Ahmed Maher Younes, Osama Ashraf Elbanna, Abd-elrahman Ali Radwan Qasem, Ibrahim Yasser Ibrahim Shahin, Gaber El-Saber Batiha
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Urolithin A exerts a protective effect on lipopolysaccharide-induced acute lung injury by regulating HMGB1-mediated MAPK and NF-κB signaling pathways Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-06 Pengfei Jiao, Yingrui Wang, Gaofei Ren, Dan Chu, Yameng Li, Yingwu Yang, Tianqing Sang
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Anti-inflammatory activity of benidipine hydrochloride in LPS-activated mammalian macrophages Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-05 Hülya Servi, Tanya Beril Korkmaz, Furkan Ayaz
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Further investigations on the influence of protein phosphatases on the signaling of muscarinic receptors in the atria of mouse hearts Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-03 Ulrich Gergs, Silke Wackerhagen, Tobias Fuhrmann, Inka Schäfer, Joachim Neumann
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Diffractaic acid exerts anti-cancer effects on hepatocellular carcinoma HepG2 cells by inducing apoptosis and suppressing migration through targeting thioredoxin reductase 1 Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-03 Emine Karaca Sulukoğlu, Şükran Günaydın, Şeyda Nur Kalın, Ahmet Altay, Harun Budak
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The protective effect and mechanism of piperazine ferulate in rats with 5/6 nephrectomy-caused chronic kidney disease Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-02 Xiu-Meng Zhang, Xin-Ran Min, Dan Li, Bo Li, Yi-Xin rui, Hong-Xiao Xie, Rong Liu, Nan Zeng
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Sonchus oleraceus L.: ethnomedical, phytochemical and pharmacological aspects Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-02 Oscar Antonio Sánchez-Aguirre, Alberto Sánchez-Medina, Enrique Juárez-Aguilar, José Martín Barreda-Castillo, Leticia Margarita Cano-Asseleih
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A switch in letters leads to the “creation” of Eszett (ß)-catenin rather than beta (β)-catenin Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-01 Jaime A. Teixeira da Silva
A simple replacement—most likely due to a linguistic error—of the Greek letter beta (β) by the German letter Eszett (ß), has led to the introduction of an error in a body of literature related to beta (β)-catenin, resulting in the “creation” of a non-existent compound and false positive, Eszett (ß)-catenin. A search on 9 December 2023 in PubMed for ß-catenin and β-catenin revealed 395 and 45,919 results
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Can acetate via FFA receptors contribute to the diabetogenic effect of statins? Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-01 Finn Olav Levy, Jan-Bjørn Osnes
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Progress in discovery and development of natural inhibitors of histone deacetylases (HDACs) as anti-cancer agents Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-01 Abhishek Wahi, Priti Jain, Apurba Sinhari, Hemant R. Jadhav
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Phytochemical studies of white mulberry fruits (Morus alba L.) Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-01 Nurdaulet Zhumabayev, Kairat Zhakipbekov, Narbek Zhumabayev, Ubaidilla Datkhayev, Saken Tulemissov
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Gentiopicroside inhibits retinoblastoma cell proliferation, invasion, and tumorigenesis in nude mice by suppressing the PI3K/AKT pathway Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-02-01 Jiayang Yin, Feng Zhang, Jiamin Cao, Zhaochangci Chen, Wei Xiong
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Verification of nucleotide sequence reagent identities in original publications in high impact factor cancer research journals Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-09 Pranujan Pathmendra, Yasunori Park, Francisco J. Enguita, Jennifer A. Byrne
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Evaluation of the protective effect of losartan in acetaminophen-induced liver and kidney damage in mice Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-09 Serkan Şahin, Ayça Çakmak Aydın, Ayşe Yeşim Göçmen, Emin Kaymak
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Role of hippocampal and prefrontal cortical cholinergic transmission in combination therapy valproate and cannabidiol in memory consolidation in rats: involvement of CREB- BDNF signaling pathways Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-08 Navid Fatahi, Majid Jafari-Sabet, Gelareh Vahabzadeh, Alireza Komaki
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TLQP-21 facilitates diabetic wound healing by inducing angiogenesis through alleviating high glucose-induced injuries on endothelial progenitor cells Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-06 Yaqi Fang, Yuexia Zhu, Minxia Zhang, Hua Ying, Yubo Xing
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Protective effects of 4-methylumbelliferone on myocardial ischemia/reperfusion injury in rats through inhibition of oxidative stress and downregulation of TLR4/NF-κB/NLRP3 signaling pathway Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-06 Alireza Moradi, Mohammad Reza Aslani, Hamzeh Mirshekari Jahangiri, Nasim Naderi, Nahid Aboutaleb
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Chronic Cinacalcet improves skin flap survival in rats: the suggested role of the nitric oxide pathway Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-06 Mostafa Akbariani, Farahnaz Bidari Zerehpoosh, Zohreh Shahabi, Amir Shadboorestan, Zahra Hami, Ehsan Nasiroleslami, Sevda Shayesteh, Mohsen Chamanara, Ahmad Reza Dehpour
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Sesamol as a potent anticancer compound: from chemistry to cellular interactions Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-05 Ajay Kumar, Payal Bajaj, Brahmjot Singh, Kapil Paul, Pooja Sharma, Sukanya Mehra, Robin, Pardeep Kaur, Shivam Jasrotia, Parveen Kumar, Rajat, Vipourpreet Singh, Hardeep Singh Tuli
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Chemical composition, biological activities, and molecular mechanism of Inula viscosa (L.) bioactive compounds: a review Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-05 Sara Ouari, Nadia Benzidane
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Long-term efficacies of selective vasodilators in pulmonary arterial hypertension: a comprehensive comparison using a spontaneous reporting database Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-05 Koji Suzuki, Tatsuya Yagi, Junichi Kawakami
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Remdesivir: treatment of COVID-19 in special populations Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-05
Abstract Remdesivir (RDV) is the mainstay antiviral therapy for moderate to severe COVID-19. Although remdesivir was the first drug approved for COVID-19, information about its efficacy and safety profile is limited in a significant segment of the population, such as people with underlying diseases, the elderly, children, and pregnant and lactating women. The efficacy and safety profile of RDV in disease
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Effectiveness of epidural morphine for the treatment of cancer pain in patients with gastrointestinal neoplasm—a systematic review Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-05 Yasmim Jianjulio Nassif, Maria Elisa Zanin, Joselin Valeska Martinez-Sobalvarro, Carlos Marcelo de Barros, Maurílio Pacheco-Neto, Tiago Marques dos Reis, Márcia Helena Miranda Cardoso-Podestá, Larissa Helena Torres
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Hypericum perforatum: a comprehensive review on pharmacognosy, preclinical studies, putative molecular mechanism, and clinical studies in neurodegenerative diseases Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-04 Meghraj Vivekanand Suryawanshi, Pranjal P. Gujarathi, Taufik Mulla, Imtiyaz Bagban
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Initial characterization of a transgenic mouse with overexpression of the human D1-dopamine receptor in the heart Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-04
Abstract Dopamine can exert effects in the mammalian heart via five different dopamine receptors. There is controversy whether dopamine receptors increase contractility in the human heart. Therefore, we have generated mice that overexpress the human D1-dopamine receptor in the heart (D1-TG) and hypothesized that dopamine increases force of contraction and beating rate compared to wild-type mice (WT)
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Changes in estimated glomerular filtration rate in patients administered proton pump inhibitors: a single-center cohort study Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-03
Abstract Proton pump inhibitor (PPI) use may be associated with renal dysfunction. Renal dysfunction in PPI users requires evaluation of development and progression risks simultaneously, using estimated glomerular filtration rate (eGFR) slope, which indicates changes in eGFR per year. To the best of our knowledge, no studies have evaluated eGFR slope in PPI users. This study investigated the association
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Diosgenin potentiates the anticancer effect of doxorubicin and volasertib via regulating polo-like kinase 1 and triggering apoptosis in hepatocellular carcinoma cells Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-02
Abstract A common approach to cancer therapy is the combination of a natural product with chemotherapy to overcome sustained cell proliferation and chemotherapy resistance obstacles. Diosgenin (DG) is a phytosteroidal saponin that is naturally present in a vast number of plants and has been shown to exert anti-cancer activities against several tumor cells. Herein, we assessed the chemo-modulatory effects
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Gastrodin: a comprehensive pharmacological review Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-02 Yulin Wang, Mengting Bai, Xian Wang, Zhaolei Peng, Chunyan Cai, Jingjing Xi, Chunmei Yan, Jia Luo, Xiaofang Li
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PDE3B regulates KRT6B and increases the sensitivity of bladder cancer cells to copper ionophores Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-02 Yuankang Feng, Zhenlin Huang, Liang Song, Ningyang Li, Xiang Li, Huihui Shi, Ruoyang Liu, Fubo Lu, Xu Han, Yafei Ding, Yinghui Ding, Jun Wang, Jinjian Yang, Zhankui Jia
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Arenobufagin regulates the p62-Keap1-Nrf2 pathway to induce autophagy-dependent ferroptosis in HepG2 cells Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2024-01-02
Abstract Hepatocellular carcinoma (HCC) is the most prevalent type of primary liver cancer, accounting for the overwhelming majority of malignant liver tumors. Therefore, how to effectively prevent and cure HCC has become a research hotspot. Many studies have shown that arenobufagin can induce apoptosis, ferroptosis, and autophagy of tumor cells. An increasing number of studies have shown that autophagy
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Daidzein nanosuspension in combination with cisplatin to enhance therapeutic efficacy against A549 non-small lung cancer cells: an in vitro evaluation Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2023-12-30 Seyma Oncu, Merve Becit-Kizilkaya, Serkan Sen, Afife Busra Ugur-Kaplan, Meltem Cetin, Sefa Celik
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Apigenin protects melanocytes and improve tyrosinase activity in a hydroquinone induced vitiligo mouse model targeting P38 MAP kinase signaling: histopathology and immunohistochemistry analysis Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2023-12-29 Kanupriya Chauhan, Falguni Goel, Shamsher Singh
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The effect of intra-nasal co-treatment with insulin and growth factor-rich serum on behavioral defects, hippocampal oxidative-nitrosative stress, and histological changes induced by icv-STZ in a rat model Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2023-12-29
Abstract Impaired insulin and growth factor functions are thought to drive many alterations in neurodegenerative diseases like dementia and seem to contribute to oxidative stress and inflammatory responses. Recent studies revealed that nasal growth factor therapy could induce neuronal and oligodendroglia protection in rodent brain damage induction models. Impairment of several growth factors signaling
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The role of beta-adrenoreceptors in postoperative ileus in rats Naunyn-Schmiedeberg's Arch. Pharmacol. (IF 3.6) Pub Date : 2023-12-29
Abstract The aim of the research was to evaluate the influence of antagonists of specific beta-adrenergic receptor subtypes on bowel motility following abdominal surgery in rat model of postoperative ileus. Bowel motility was measured by the intestinal transit of Evans blue introduced via orogastric tube after surgical procedures of skin incision, laparotomy and laparotomy with gut manipulation. Male