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The effects of pramipexole on motivational vigour during a saccade task: a placebo-controlled study in healthy adults Psychopharmacology (IF 3.4) Pub Date : 2024-03-18 Sheena K. Au-Yeung, Don Chamith Halahakoon, Alexander Kaltenboeck, Philip Cowen, Michael Browning, Sanjay G Manohar
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Long-term disruption of tissue levels of glutamate and glutamatergic neurotransmission neuromodulators, taurine and kynurenic acid induced by amphetamine Psychopharmacology (IF 3.4) Pub Date : 2024-03-14 Ewa Taracha, Magdalena Czarna, Danuta Turzyńska, Alicja Sobolewska, Piotr Maciejak
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Synergistic use of deep TMS therapy with IV ketamine infusions for major depressive disorder: a pilot study Psychopharmacology (IF 3.4) Pub Date : 2024-03-12 Nathaniel A. Shanok, Sabrina Muzac, Leah Brown, Melissa Barrera, Raul Rodriguez
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Noribogaine acute administration in rats promotes wakefulness and suppresses REM sleep Psychopharmacology (IF 3.4) Pub Date : 2024-03-12 Juan Pedro Castro-Nin, Diego Serantes, Paola Rodriguez, Bruno Gonzalez, Ignacio Carrera, Pablo Torterolo, Joaquín González
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The role of mGluR5 on the therapeutic effects of ketamine in Wistar rats Psychopharmacology (IF 3.4) Pub Date : 2024-03-09
Abstract Rationale Ketamine produces dissociative, psychomimetic, anxiolytic, antidepressant, and anesthetic effects in a dose dependent manner. It has a complex mechanism of action that involve alterations in other glutamate receptors. The metabotropic glutamate receptor 5 (mGluR5) has been investigated in relation to the psychotic and anesthetic properties of ketamine, while its role in mediating
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Operant social self-administration in male CD1 mice Psychopharmacology (IF 3.4) Pub Date : 2024-03-08
Abstract Rationale and Objective We recently introduced a model of operant social reward in which female CD1 mice lever press for access to affiliative social interaction with a cagemate peer mouse of the same sex and strain. Here we determined the generality of the operant social self-administration model to male CD1 mice who, under certain conditions, will lever press to attack a subordinate male
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Knowledge by omission: the significance of omissions in the 5-choice serial reaction time task Psychopharmacology (IF 3.4) Pub Date : 2024-03-06 Caroline Vouillac-Mendoza, Audrey Durand, Serge H. Ahmed, Karine Guillem
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A systematic review and meta-analysis of synthetic cathinone use and psychosis Psychopharmacology (IF 3.4) Pub Date : 2024-03-06 Rishika R. Daswani, Cassandra M. Choles, David D. Kim, Alasdair M. Barr
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Chronic REM sleep deprivation leads to manic- and OCD-related behaviors, and decreases hippocampal BDNF expression in female rats Psychopharmacology (IF 3.4) Pub Date : 2024-03-02 Nahal Abbasi, Yasaman Mirabzadeh, Golnaz Khesali, Zahra Ebrahimkhani, Hanie Karimi, Salar Vaseghi
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Changes in distinct brain systems identified with fMRI during smoking cessation treatment with varenicline: a review Psychopharmacology (IF 3.4) Pub Date : 2024-03-02 Vassilis N. Panagopoulos, Alexis Bailey, George K. Kostopoulos, Andreas A. Ioannides
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Baseline prepulse inhibition dependency of orexin A and REM sleep deprivation Psychopharmacology (IF 3.4) Pub Date : 2024-03-01 Pınar Öz, Osman Kamalı, Hacer Begüm Saka, Ceren Gör, İsmail Tayfun Uzbay
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Neurexin1α knockout in rats causes aberrant social behaviour: relevance for autism and schizophrenia Psychopharmacology (IF 3.4) Pub Date : 2024-02-29 E. J. Marijke Achterberg, Barbara Biemans, Louk J. M. J. Vanderschuren
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The acute effects of cannabis, with and without cannabidiol, on attentional bias to cannabis related cues: a randomised, double-blind, placebo-controlled, cross-over study Psychopharmacology (IF 3.4) Pub Date : 2024-02-28 Daniel Hall, Will Lawn, Shelan Ofori, Katie Trinci, Anya Borissova, Claire Mokrysz, Kat Petrilli, Michael A. P. Bloomfield, Matthew B. Wall, Tom P. Freeman, H. Valerie Curran
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Repeated Δ-9-Tetrahydrocannabinol administration dose dependently increases stablished schedule-induced drinking Psychopharmacology (IF 3.4) Pub Date : 2024-02-28 Esmeralda Fuentes-Verdugo, Ricardo Pellón, Miguel Miguéns
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Calcitriol attenuates lipopolysaccharide-induced neuroinflammation and depressive-like behaviors by suppressing the P2X7R/NLRP3/caspase-1 pathway Psychopharmacology (IF 3.4) Pub Date : 2024-02-27
Abstract Rationale Microglia-mediated neuroinflammation is a vital hallmark in progression of depression, while calcitriol exerts anti-inflammatory effects in the brain. The activation of the P2X7 receptor has an important link to neuroinflammation. However, it is unclear whether calcitriol treatment exerts anti-inflammatory effects in association with P2X7R activation. Objective In this study, we
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Gut microbiota connects the brain and the heart: potential mechanisms and clinical implications Psychopharmacology (IF 3.4) Pub Date : 2024-02-26 Yi Zhang, Kai Huang, Jiahao Duan, Rong Zhao, Ling Yang
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Effects of estrogen on spatial navigation and memory Psychopharmacology (IF 3.4) Pub Date : 2024-02-26 Gina Joue, Tobias Navarro-Schröder, Johannes Achtzehn, Scott Moffat, Nora Hennies, Johannes Fuß, Christian Döller, Thomas Wolbers, Tobias Sommer
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Associations between hair-derived cannabinoid levels, self-reported use, and cannabis-related problems Psychopharmacology (IF 3.4) Pub Date : 2024-02-26
Abstract Rationale As cannabis potency and cannabis use are increasing in newly legalized markets, it is increasingly important to measure and examine the effects of cannabinoid exposure. Objectives The current study aims to assess how hair-derived cannabinoid concentrations – offering insight into three-month cumulative exposure – are associated with common self-report measures of cannabis use and
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CaMKIIa+ neurons in the bed nucleus of the stria terminalis modulate pace of natural reward seeking depending on internal state Psychopharmacology (IF 3.4) Pub Date : 2024-02-24 Patty T. Huijgens, Roy Heijkoop, Louk J.M.J. Vanderschuren, Heidi M.B. Lesscher, Eelke M.S. Snoeren
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Dorsal hippocampal astrocytes mediate the development of heroin withdrawal-enhanced fear learning Psychopharmacology (IF 3.4) Pub Date : 2024-02-24 Shveta V. Parekh, Lydia O. Adams, Gillian A. Barkell, Jacqueline E. Paniccia, Kathryn J. Reissner, Donald T. Lysle
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A dose-ranging study of the physiological and self-reported effects of repeated, rapid infusion of remifentanil in people with opioid use disorder and physical dependence on fentanyl Psychopharmacology (IF 3.4) Pub Date : 2024-02-22 Joshua A. Lile, Thomas P. Shellenberg, Shanna Babalonis, Kevin W. Hatton, Lon R. Hays, Abner O. Rayapati, William W. Stoops, Michael J. Wesley
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Attenuated incubation of ethanol-induced conditioned taste aversion in a model of dependence Psychopharmacology (IF 3.4) Pub Date : 2024-02-22 Lindsey A. Ramirez, Kathryn R. Przybysz, Joseph R. Pitock, E. Margaret Starr, Hyerim Yang, Elizabeth J. Glover
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Synergistic antidepressant-like effect of citicoline and CB 1 agonist in male mice Psychopharmacology (IF 3.4) Pub Date : 2024-02-21 Aysan Amanzade, Fatemeh Khakpai, Mohammad-Reza Zarrindast
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Withdrawal syndrome after antipsychotics discontinuation: an analysis of the WHO database of spontaneous reports (Vigibase) between 2000 and 2022 Psychopharmacology (IF 3.4) Pub Date : 2024-02-20 Wilhelm Storck, Tanguy Taillefer de Laportalière, Antoine Yrondi, Hervé Javelot, Fabrice Berna, François Montastruc
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The role of the peripheral and central adrenergic system in the construction of the subjective emotional experience of panic Psychopharmacology (IF 3.4) Pub Date : 2024-02-16 Jette H. de Vos, Koen R. J. Schruers, Glen Debard, Bert Bonroy, David E. J. Linden, Nicole K. Leibold
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Effects of arginine vasopressin on human anxiety and associations with sex, dose, and V1a-receptor genotype Psychopharmacology (IF 3.4) Pub Date : 2024-02-15
Abstract Rationale Arginine vasopressin (AVP) has dose- and sex-specific effects on social behavior, and variation in social responses is related to variation in the V1a receptor gene in animals. Whether such complexity also characterizes AVP effects on anxiety in humans, or whether V1a genotype is related to anxiety and/or AVP’s ability to affect it, remains to be determined. Objective To test if
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Distinct roles of the left and right prelimbic cortices in the modulation of ethanol consumption in male mice under acute and chronic social defeat stress Psychopharmacology (IF 3.4) Pub Date : 2024-02-13 Lucas Canto-de-Souza, Daniela Baptista-de-Souza, Ricardo Luiz Nunes-de-Souza, Cleopatra Planeta
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The impact of doxycycline on human contextual fear memory Psychopharmacology (IF 3.4) Pub Date : 2024-02-09 Jelena M. Wehrli, Yanfang Xia, Aslan Abivardi, Birgit Kleim, Dominik R. Bach
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Individual differences in GHB consumption in a new voluntary GHB self-administration model in outbred rats Psychopharmacology (IF 3.4) Pub Date : 2024-02-09
Abstract Background and purpose The use of the recreational drug gamma-hydroxybutyric acid (GHB) has increased over the past decade, concomitantly leading to a higher incidence of GHB use disorder. Evidence-based treatment interventions are hardly available and cognitive effects of long-term GHB use remain elusive. In order to study the development of GUD and the causal effects of chronic GHB consumption
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Relationship between opioid cross-tolerance during buprenorphine stabilization and return to opioid use during buprenorphine dose tapering Psychopharmacology (IF 3.4) Pub Date : 2024-02-08 Mark K. Greenwald, Tolani Sogbesan, Tabitha E.H. Moses
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Intermittent nicotine access is as effective as continuous access in promoting nicotine seeking and taking in rats Psychopharmacology (IF 3.4) Pub Date : 2024-02-07 Hajer E. Algallal, Vincent Jacquemet, Anne-Noël Samaha
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Diosgenin alleviates alcohol-mediated escalation of social defeat stress and the neurobiological sequalae Psychopharmacology (IF 3.4) Pub Date : 2024-02-05 Benneth Ben-Azu, Emuesiri Goodies Moke, Lilian E. Chris-Ozoko, Efe J. Jaiyeoba-Ojigho, Olusegun G. Adebayo, Abayomi Mayowa Ajayi, Mega O. Oyovwi, Gideon Odjugo, Vincent I. Omozojie, Goddey Ejomafuwe, Nzubechukwu Onike, Aya-Ebi O. Eneni, Chukwuyenum P. Ichipi-Ifukor, Ifeakachuku F. Achuba
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Rapamycin attenuates reconsolidation of a backwards-conditioned aversive stimuli in female mice Psychopharmacology (IF 3.4) Pub Date : 2024-02-05 Jared Trask, Phillip E. MacCallum, Haley Rideout, Evan L. Preisser, Jacqueline J. Blundell
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Subthalamic high-frequency deep brain stimulation reduces addiction-like alcohol use and the possible negative influence of a peer presence Psychopharmacology (IF 3.4) Pub Date : 2024-02-03 Lucie Vignal, Cassandre Vielle, Maya Williams, Nicolas Maurice, Mickael Degoulet, Christelle Baunez
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Serum indoleamine 2, 3-dioxygenase and tryptophan-2, 3-dioxygenase: potential biomarkers for the diagnosis of major depressive disorder Psychopharmacology (IF 3.4) Pub Date : 2024-01-30
Abstract Objective The objective of this study was to observe the changes in the levels of indoleamine 2, 3-dioxygenase (IDO) and tryptophan-2, 3-dioxygenase (TDO) in patients with major depressive disorder (MDD) and investigate their potential role as novel biomarkers for diagnosing MDD. Methods A total of 55 MDD patients and 55 healthy controls (HC) were enrolled in the study. The severity of MDD
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Corydaline alleviates Parkinson’s disease by regulating autophagy and GSK-3β phosphorylation Psychopharmacology (IF 3.4) Pub Date : 2024-01-30 Kaikai Zhou, Shasha Xu
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Adult consequences of repeated nicotine and Δ9-tetrahydrocannabinol (THC) vapor inhalation in adolescent rats Psychopharmacology (IF 3.4) Pub Date : 2024-01-29 Arnold Gutierrez, Kevin M. Creehan, Yanabel Grant, Michael A. Taffe
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Acute, but not repeated, cocaine exposure alters allopregnanolone levels in the midbrain of male and female rats Psychopharmacology (IF 3.4) Pub Date : 2024-01-29 Minna H. McFarland, Meira M. F. Machado, Griffin M. Sansbury, Kate C. Musselman, Giorgia Boero, Todd K. O’Buckley, Crystal C. Carr, A. Leslie Morrow, Donita L. Robinson
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The relevance between abnormally elevated serum ceramide and cognitive impairment in Alzheimer’s disease model mice and its mechanism Psychopharmacology (IF 3.4) Pub Date : 2024-01-26 Xin Liu, Yongzeng Jin, Xinyi Cheng, Qinghua Song, Yanan Wang, Ling He, Tong Chen
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An economon model of drug addiction Psychopharmacology (IF 3.4) Pub Date : 2024-01-26
Abstract The term “economon” (i:’ka.nə.muhn; plural: economa) is introduced here to describe an economic unit composed of two participants engaged in mutually reinforcing operant behavior. Economa are basic building blocks of transactional behavior that aggregate in social networks called economies. In a drug-addiction economon, operant behavior by one participant (the “supplier”) provides an addictive
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Activation of NOP receptor increases vulnerability to stress: role of glucocorticoids and CRF signaling Psychopharmacology (IF 3.4) Pub Date : 2024-01-25 Victor A. D. Holanda, Raissa N. de Almeida, Matheus C de Oliveira, Edilson D. da Silva Junior, Nicole L. Galvão-Coelho, Girolamo Calo’, Chiara Ruzza, Elaine C. Gavioli
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Cue-exposure treatment influences resting-state functional connectivity—a randomized controlled fMRI study in alcohol use disorder Psychopharmacology (IF 3.4) Pub Date : 2024-01-23 Àlvar Farré-Colomés, Haoye Tan, Sarah Gerhardt, Martin Fungisai Gerchen, Martina Kirsch, Sabine Hoffmann, Peter Kirsch, Falk Kiefer, Sabine Vollstädt-Klein
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An automated group-housed oral fentanyl self-administration method in mice Psychopharmacology (IF 3.4) Pub Date : 2024-01-22 Noa Peretz-Rivlin, Idit Marsh-Yvgi, Yonatan Fatal, Anna Terem, Hagit Turm, Yavin Shaham, Ami Citri
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Meta-analysis and systematic review of vesicular monoamine transporter (VMAT-2) inhibitors in schizophrenia and psychosis Psychopharmacology (IF 3.4) Pub Date : 2024-01-19 Anne Connolly, Phoebe Wallman, Olubanke Dzahini, Oliver Howes, David Taylor
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Aripiprazole and its adverse effects in the form of impulsive-compulsive behaviors: A systematic review of case reports Psychopharmacology (IF 3.4) Pub Date : 2024-01-16 Mehdi Akbari, Shiva Jamshidi, Sonay Sheikhi, Farhad Alijani, Parsa Kafshchi, David Taylor
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Pharmaco-toxicological effects of the novel tryptamine hallucinogen 5-MeO-MiPT on motor, sensorimotor, physiological, and cardiorespiratory parameters in mice—from a human poisoning case to the preclinical evidence Psychopharmacology (IF 3.4) Pub Date : 2024-01-12
Abstract Rationale The 5-methoxy-N-methyl-N-isopropyltryptamine (5-MeO-MiPT, known online as “Moxy”) is a new psychedelic tryptamine first identified on Italian national territory in 2014. Its hallucinogen effects are broadly well-known; however, only few information is available regarding its pharmaco-toxicological effects. Objectives Following the seizure of this new psychoactive substances by the
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Effects of social housing conditions on ethanol-induced behavioral sensitization in Swiss mice Psychopharmacology (IF 3.4) Pub Date : 2024-01-11 Théo van Ingelgom, Vincent Didone, Leeloo Godefroid, Étienne Quertemont
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Combination strategy employing BACE1 inhibitor and memantine to boost cognitive benefits in Alzheimer’s disease therapy Psychopharmacology (IF 3.4) Pub Date : 2024-01-10 Abu Md Mamun Tarif, Hasi Huhe, Masuo Ohno
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Levels of neuronal pentraxin 2 in plasma is associated with cognitive function in patients with schizophrenia Psychopharmacology (IF 3.4) Pub Date : 2024-01-08 Jiahui Zhou, Xiaojing Li, Xiujuan Wang, Yongfeng Yang, Aoyang Nai, Han Shi, Jingyuan Zhao, Jianhong Zhang, Shuang Ding, Yong Han, Qing Liu, Luwen Zhang, Tengfei Chen, Bing Liu, Weihua Yue, Luxian Lv, Wenqiang Li
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Pharmacological diacylglycerol lipase inhibition impairs contextual fear extinction in mice Psychopharmacology (IF 3.4) Pub Date : 2024-01-06 Liorimar Ramos-Medina, Luis E. Rosas-Vidal, Sachin Patel
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Nucleus accumbens core dopamine D2 receptors are required for performance of the odor span task in male rats Psychopharmacology (IF 3.4) Pub Date : 2024-01-06 Timothy J. Onofrychuk, Ashton L. Heidt, Spencer N. Orvold, Quentin Greba, John G. Howland
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Insight into differing decision-making strategies that underlie cognitively effort-based decision making using computational modeling in rats Psychopharmacology (IF 3.4) Pub Date : 2024-01-03
Abstract Rationale The rat cognitive effort task (rCET), a rodent model of cognitive rather than physical effort, requires animals to choose between an easy or hard visuospatial discrimination, with a correct hard choice more highly rewarded. Like in humans, there is stable individual variation in choice behavior. In previous reports, animals were divided into two groups—workers and slackers—based
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Mice with an autism-associated R451C mutation in neuroligin-3 show intact attention orienting but atypical responses to methylphenidate and atomoxetine in the mouse-Posner task Psychopharmacology (IF 3.4) Pub Date : 2024-01-03 Shuting Li, Carlos May, Terence Y. Pang, Leonid Churilov, Anthony J. Hannan, Katherine A. Johnson, Emma L. Burrows
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The imidazoline I2 receptor agonist 2-BFI reduces abuse-related effects of morphine: self-administration and drug discrimination Psychopharmacology (IF 3.4) Pub Date : 2023-12-30 Justin N. Siemian, Kristen Woodhouse, David H. Liu, Yanan Zhang, Jun-Xu Li
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The effect of psychoactive bacteria, Bifidobacterium longum Rosell®-175 and Lactobacillus rhamnosus JB-1, on brain proteome profiles in mice Psychopharmacology (IF 3.4) Pub Date : 2023-12-29 Łukasz S. Jarosz, Katarzyna Socała, Katarzyna Michalak, Adrian Wiater, Artur Ciszewski, Małgorzata Majewska, Agnieszka Marek, Zbigniew Grądzki, Piotr Wlaź
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Lack of effect of methamphetamine on reward-related brain activity in healthy adults Psychopharmacology (IF 3.4) Pub Date : 2023-12-23 Connor J. Haggarty, James E. Glazer, Robin Nusslock, Royce Lee, Harriet de Wit
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The ad-libitum taste test as measure of momentary alcohol use in the laboratory: an investigation of construct validity and confounding factors Psychopharmacology (IF 3.4) Pub Date : 2023-12-23 Sebastian Trautmann, Anja Kräplin, Markus Muehlhan, Fée Ona Fuchs, Beate Loesch, Charlotte Wittgens
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Allosteric inhibition of phosphodiesterase 4D induces biphasic memory-enhancing effects associated with learning-activated signaling pathways Psychopharmacology (IF 3.4) Pub Date : 2023-12-19 Kohei Jino, Keisuke Miyamoto, Tomoe Kanbara, Chie Unemura, Naotaka Horiguchi, Yukio Ago
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Randomized controlled trial of propranolol on social communication and anxiety in children and young adults with autism spectrum disorder Psychopharmacology (IF 3.4) Pub Date : 2023-12-13 David Q. Beversdorf, Bradley Ferguson, Samantha Hunter, Kathy Hirst, Bridget Lolli, Katherine R. Bellesheim, Amy U. Barton, Julie Muckerman, Nicole Takahashi, Kimberly Selders, Ryan Holem, Kristin Sohl, Peter Dyke, Janine Stichter, Micah Mazurek, Stephen Kanne
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Effect of prenatal and early post-natal oxycodone exposure on the reinforcing and antinociceptive effects of oxycodone in adult C57BL/6 J mice Psychopharmacology (IF 3.4) Pub Date : 2023-12-13 Yong Zhang, Eduardo R. Butelman, Mary Jeanne Kreek