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Prognostic factors in clinicopathology of oesophagogastric adenocarcinoma: a single-centre longitudinal study of 347 cases over a 20-year period Pathology (IF 4.5) Pub Date : 2024-02-27 Qin Huang, Edward Lew, Yuqing Cheng, Kevin Huang, Vikram Deshpande, Shweta Shinagare, Xin Yuan, Jason S. Gold, Daniel Wiener, H. Christian Weber
Oesophagogastric adenocarcinoma (EGA) includes oesophageal (EA), gastro-oesophageal junctional (GEJA), and gastric (GA) adenocarcinomas. The prognostic values of clinicopathological factors in these tumours remain obscure, especially for GEJA that has been inconsistently classified and staged. We studied the prognosis of EGA patients among the three geographic groups in 347 consecutive patients with
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Clinical profile and serological correlation with haemolysis in DAT-positive autoimmune haemolytic anaemia patients in Bangladesh Pathology (IF 4.5) Pub Date : 2024-02-24 Anika Mahmood, Ayesha Khatun, Mahamudul Hasan, Sonia Shormin Miah, Md Mazharul Hoque Tapan, Atiar Rahman
Discerning the type of autoimmune haemolytic anaemia (AIHA) is crucial for transfusion support and initiation of treatment. This study aimed to establish the clinical profile and serological character of red cell autoantibodies and to investigate the relationship with haemolysis in AIHA patients who were direct antiglobulin test (DAT)-positive.
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Cutaneous diatoms from diatomaceous earth mimicking myiasis infection Pathology (IF 4.5) Pub Date : 2024-02-17 Simon F. Roy, Goran Micevic, Jennifer M. McNiff, Sean R. Christensen, Shawn E. Cowper
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Granuloma formation is insufficient for differentiating hidradenitis suppurativa and cutaneous Crohn's disease Pathology (IF 4.5) Pub Date : 2024-02-17 Moeza Arona Merchant, Timothy Liu, Erin McMeniman, Duncan Lambie
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Epithelioid cell histiocytoma associated with IRF2BP2::NTRK1 fusion Pathology (IF 4.5) Pub Date : 2024-02-17 Benjamin A. Wood, Urszula Carr, Chris Van Vliet, Nima Mesbah Ardakani
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SMARCA4 deficiency and mutations are frequent in large cell lung carcinoma and are prognostically significant Pathology (IF 4.5) Pub Date : 2024-02-15 Alvin Ho-Kwan Cheung, Kit-Yee Wong, Shuk-Ling Chau, Fuda Xie, Zeta Mui, Gordon Yuan-Ho Li, Molly Siu Ching Li, Joanna Tong, Calvin Sze-Hang Ng, Tony S. Mok, Wei Kang, Ka-Fai To
SMARCA4 mutation has emerged as a marker of poor prognosis in lung cancer and has potential predictive value in cancer treatment, but recommendations for which patients require its investigation are lacking. We comprehensively studied alterations and the clinicopathological significance in a large cohort of immunohistochemically-subtyped non-small cell lung cancer (NSCLC). A total of 1416 patients
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The frequency and clinical outcome of mono-hit and multi-hit TP53 aberrations in newly diagnosed multiple myeloma Pathology (IF 4.5) Pub Date : 2024-02-15 Sreejesh Sreedharanunni, Shelly Singla, Anand Balakrishnan, Archana Singh, Manu Jamwal, Namrata Singh, Charanpreet Singh, Aditya Jandial, Deepesh Lad, Praveen Sharma, Man Updesh Singh Sachdeva, Pankaj Malhotra, Reena Das
We investigated the frequency and outcome of mono-hit and multi-hit aberrations [biallelic or ≥1 mutations () or with variant allele frequency (VAF) ≥55%] in an Indian cohort of newly diagnosed multiple myeloma (NDMM) patients. We employed fluorescence in situ hybridisation (FISH; =457) and targeted next-generation sequencing (NGS; =244) on plasma cell-enriched samples. We also studied the impact of
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Observations from a national sample exchange program for molecular haematology testing Pathology (IF 4.5) Pub Date : 2024-02-12 Clare Gould, Michelle McBean, Ella Thompson, Jennifer Lickiss, Ing Soo Tiong, David Westerman, Piers Blombery
External quality assessment programs (EQAP) for molecular haematology generally only assess the analytical phase of laboratory testing or provide limited evaluation of post-analytical components. We incorporated comprehensive post-analytical evaluation into an existing national inter-laboratory sample exchange program for molecular haematology due to the increasing complexity of diagnostic molecular
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Non-coding RNA and gene expression analyses of papillary renal neoplasm with reverse polarity (PRNRP) reveal distinct pathological mechanisms from other renal neoplasms Pathology (IF 4.5) Pub Date : 2024-02-07 Stéphane Nemours, María Armesto, María Arestín, Claudia Manini, Doriana Giustetto, Maris Sperga, Kristyna Pivovarcikova, Delia Pérez-Montiel, Ondrej Hes, Michal Michal, José I. López, Charles H. Lawrie
Papillary renal neoplasm with reversed polarity (PRNRP) is a recently described rare renal neoplasm. Traditionally, it was considered a variant of papillary renal cell carcinoma (PRCC). However, several studies reported significant differences between PRNRP and PRCC in terms of clinical, morphological, immunohistochemical and molecular features. Nonetheless, PRNRP remains a poorly understood entity
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Effects of blood sample storage time, temperature, anti-coagulants and blood stabiliser on lymphocyte phenotyping Pathology (IF 4.5) Pub Date : 2024-02-07 Yunyu Lao, Alex Quach, Khalida Perveen, Charles Hii, Antonio Ferrante
Medical diagnostic laboratories have come under further scrutiny to ensure quality standards of their service and external quality assurance (EQA) programs involving multiple laboratories have been used to gauge this quality based on a consensus. However, because of the geographical distances within a country or internationally, cell surface marker expressions may change due to time delays and transport
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Red cell antibodies: frequency in the Western Australian Antibody Register and Australian blood donor populations Pathology (IF 4.5) Pub Date : 2024-02-06 Georgina Jacko, Tanya Powley, Tanya Cawthorne, Zhi Tan, James Daly
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Pathology: the narrative continues Pathology (IF 4.5) Pub Date : 2024-02-01 R, i, c, h, a, r, d, , A, ., , S, c, o, l, y, e, r
Abstract not available
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Mpox detection in clinical specimens by three commercial real-time PCR assays demonstrates comparable results Pathology (IF 4.5) Pub Date : 2024-02-01 Siobhan Hurley, Ki Wook Kim, Ana Domazetovska, Cynthia Yau, Malinna Yeang, Linda Donovan, Jen Kok, William Rawlinson
Abstract not available
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Clinical significance of low level JAK2 V617F in peripheral blood testing Pathology (IF 4.5) Pub Date : 2024-02-01 Matthew Rubic, Linda Lee, William Stevenson
Abstract not available
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Pathology: evolution not revolution Pathology (IF 4.5) Pub Date : 2024-02-01 J, o, h, n, , R, ., , B, u, r, n, e, t, t
Abstract not available
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Primary genital tract tuberculosis in a postmenopausal Australian woman: a rare case report Pathology (IF 4.5) Pub Date : 2024-01-27 Han Lin Aung, Samuel Foong, Alyona Dziouba, Preeti Patil, Ivana Rizzuto
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Assessment of variant penetrance may improve the specificity of reproductive genetic carrier screening Pathology (IF 4.5) Pub Date : 2024-01-27 Samuel Cotton
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An overview of critical incidents deaths Pathology (IF 4.5) Pub Date : 2024-01-27 Issabella Brouwer, Sairita Maistry
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Merkel cell carcinoma and polyomavirus in a high UV index population Pathology (IF 4.5) Pub Date : 2024-01-27 N. Abeysekera, D. Xing, M. Lyle, K. Merollini, A. Gill, L. Banney, R. Donkin, A. Dettrick
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A rare case of Volvariella volvacea pneumonia Pathology (IF 4.5) Pub Date : 2024-01-27 Wenjie Huang, Mei Gie Tan, Chun Yuen Chow, Yen Ee Tan
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The impact of ABO blood group on ALP reference values Pathology (IF 4.5) Pub Date : 2024-01-27 K. Rankin, M.P. Nascimento, M. Theophilos, C. Lynch, A. Carter, K.A. Sikaris
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A comparative analysis of phenotypic susceptibility methodologies in non-diphtheriae corynebacterial Pathology (IF 4.5) Pub Date : 2024-01-27 Suzanne English, Bradley Watson, John Merlino, Rebecca Davis
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Tumours of the nipple – evidence gaps mapped from the fifth edition of the WHO classification of tumours of the breast: preliminary results Pathology (IF 4.5) Pub Date : 2024-01-27 Zi Long Chow, Nur Diyana Md Nasir, Menaka Dilani Samarawickrema Lokuhetty, Puay Hoon Tan
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Intravascular large B-cell lymphoma presenting in the prostate Pathology (IF 4.5) Pub Date : 2024-01-27 Hamish Smith, Vipul Vyas
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Cortar: quantifying and reporting variant associated mis-splicing from RNA-sequencing Pathology (IF 4.5) Pub Date : 2024-01-27 Rhett G. Marchant, Adam M. Bournazos, Himanshu Joshi, Sandra T. Cooper
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How the Australian Functional Genomics Network (AFGN) contributes to improved patient care Pathology (IF 4.5) Pub Date : 2024-01-27 Hamish S. Scott, Ebony Matotek, Tessa Mattiske, Robert J. Bryson-Richardson, Ian Smyth, Jozef Gecz, John Christodoulou, Nathan Palpant, Kelly Smith, Coral Warr, Bruce Bennetts, Paul Thomas, Josephine Bowles, Massimo Hilliard, Gary Hime, Livia Hool, Leonie Quinn, Ernst Wolvetang, Robyn Jamieson, Gareth Baynam, Tracy Dudding-Byth, Tiong Yang Tan, Di Milnes, Mathew Wallis, Elizabeth Palmer, Chirag Patel
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Drug deaths – to autopsy or not to autopsy? Pathology (IF 4.5) Pub Date : 2024-01-27 L. Iles, M. Burke, M. Archer, C. Zhou
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Top End forensic imaging Pathology (IF 4.5) Pub Date : 2024-01-27 Marianne Tiemensma, Sarah Constantine
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Estimating the burden of undiagnosed Ureaplasma species and Mycoplasma hominis infection/colonisation in lung and renal transplant patients, and establishing antimicrobial susceptibility testing for these organisms in New Zealand Pathology (IF 4.5) Pub Date : 2024-01-27 Andrew Fox-Lewis, Sally Roberts, Owen B. Spiller
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Primary salivary gland carcinoma with unusual morphologic features Pathology (IF 4.5) Pub Date : 2024-01-27 Jack Naughton, Anthony Longano
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A neuropathological perspective on fetal holocarboxylase synthetase deficiency Pathology (IF 4.5) Pub Date : 2024-01-27 Kyra J. Lyell, Martin A. Weber, Antonia W. Shand, Rita Caldas, Aparna Ramachandran, James Christie, P. Ian Andrews, Jason Pinner, Michael L. Rodriguez
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Absence of integrated bone marrow biopsy reporting significantly impacts diagnosis of acute myeloid leukaemia – a retrospective study Pathology (IF 4.5) Pub Date : 2024-01-27 Matthew Tong, Ashley McEwan, Heather Range, Omali Pitiyarachchi, Rebecca Han Nguyen, Joseph Descallar, John Dang Trinh Nguyen, Bartlomiej Getta, Lindsay Dunlop, Nicholas Viiala
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Megakaryocytes in effusion cytology – a potential diagnostic pitfall Pathology (IF 4.5) Pub Date : 2024-01-27 Hui Min Tan, Min En Nga
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Acute behavioural disturbance – what do we mean? Pathology (IF 4.5) Pub Date : 2024-01-27 Margaret Stark
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Squamoid cysts of the pancreatic duct – an innocent pancreatic cyst Pathology (IF 4.5) Pub Date : 2024-01-27 Eva Tang, Khashayar Asadi
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The differential diagnosis of ischemic colitis Pathology (IF 4.5) Pub Date : 2024-01-27 Rhonda K. Yantiss
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Keratomycosis secondary to Scedosporium species Pathology (IF 4.5) Pub Date : 2024-01-27 Wenjie Huang, Mei Gie Tan, Yen Ee Tan
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A rare diagnosis of autosomal recessive recurrent biparental complete hydatidiform mole: the importance of clinical history and genetic testing Pathology (IF 4.5) Pub Date : 2024-01-27 Jennifer Phan, Shanna Kerin, Wendy Waters, Theresa Power, Sui Yu, Tristan Hardy
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A challenging case of eosinophilic meningitis Pathology (IF 4.5) Pub Date : 2024-01-27 Yu-Ting Tina Wang, Preeti Chaudhri
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Fibrosis in long-term liver allograft Pathology (IF 4.5) Pub Date : 2024-01-27 Jo Lin Tee, Jennifer Borowsky
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Osseous metaplasia in a case of clear cell renal cell carcinoma: a case report and literature review Pathology (IF 4.5) Pub Date : 2024-01-27 Nabaa Agha, Dimuth N. Gunawardane
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Epidemiology of multi-resistant Gram-negative bacilli (MRGNR) in Great Western NSW Pathology (IF 4.5) Pub Date : 2024-01-27 Balotlhanyi Mokotedi, Harsha Samarasekara
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Assessing equity in Medicare-funded breast cancer genetic testing Pathology (IF 4.5) Pub Date : 2024-01-27 Essra Bartlett
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Detection of IFNAR1 GLU386* loss-of-function variant in dried blood spot cards Pathology (IF 4.5) Pub Date : 2024-01-27 See-Tarn Woon, Felicia Tjandra, John Mackay, Thomas Lumley, Pippa Grainger, Andrew Wood, Kuang-Chih Hsiao, Rohan Ameratunga
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Ossifying fibromyxoid tumour with atypical features: a case report and review of literature Pathology (IF 4.5) Pub Date : 2024-01-27 Alexander A. Borecki, Mitali Fadia
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CD68 positive alveolar soft part sarcoma – a case report and review of the literature Pathology (IF 4.5) Pub Date : 2024-01-27 Richi Jiang, John Slavin, Benjamin Popp
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Malignant struma ovarii – a case report and literature review Pathology (IF 4.5) Pub Date : 2024-01-27 Hannah Sawkins, Deborah Smith, Peter Hutson
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Comparing formic acid vs hydrochloric acid decalcification protocols on immunohistochemistry of bone marrow trephine biopsies Pathology (IF 4.5) Pub Date : 2024-01-27 Wan Danial Noor, Muhajir Mohamed
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Paediatric lingual hamartoma: a 12-year review of lingual hamartomas diagnosed at an Australian tertiary children’s hospital Pathology (IF 4.5) Pub Date : 2024-01-27 Donya Tohidi-Esfahani, Helen Doyle, Ali Moghimi, Michael Krivanek, Nicole Graf
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A laboratory review of significant hypogammaglobulinaemia – an opportunity for intervention? Pathology (IF 4.5) Pub Date : 2024-01-27 Sarah Thang, Aruna Kodituwakku, David Gillis
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Translating p53 immunohistochemistry into laboratory practice in myeloid malignancies Pathology (IF 4.5) Pub Date : 2024-01-27 Ricky Nelles, Michael Tallack, Courtney Tate, Stewart Hunt, Hnin Aung, Louise Seymour
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Artificial intelligence in anatomical pathology – ethical and regulatory considerations Pathology (IF 4.5) Pub Date : 2024-01-27 Sarushen Gounden
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Chronic lymphocytic leukemia: a case report with an unusual finding Pathology (IF 4.5) Pub Date : 2024-01-27 Kristopher Wilckens, Afaq Khan
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A cryptic case of clonal evolution in a PDGFRA-rearranged myeloid neoplasm Pathology (IF 4.5) Pub Date : 2024-01-27 William Nicol, Sarah Thang, Ricky Nelles, Sarbjit Riyat, Hnin Aung, David Gillis, Louise Seymour, Bronwyn Williams
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Estimation of low IgG concentration using the globulin gap Pathology (IF 4.5) Pub Date : 2024-01-27 Ke Li Chow, Kathryn Patchett, Kahn Preece, Theo de Malmanche
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The whether, whither or wither of allergen microarrays Pathology (IF 4.5) Pub Date : 2024-01-27 Karl Baumgart
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Arteriovenous malformation within a thyroid nodule – a rare mimic of malignancy and cause of increased vascularity Pathology (IF 4.5) Pub Date : 2024-01-27 Catherine G.Y. Ngan, Tiffany Symes