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Pediatric suicide: Review of a preventable tragedy Dis Mon (IF 4.0) Pub Date : 2024-03-12 Donald E. Greydanus MD Dr. HC (ATHENS), Ahsan Nazeer MD, Zheala Qayyum MD MMsc, Dilip R. Patel MD MBA MPH, Rebecca Rausch PhD, Linh-Nhu Hoang MA, Caroline Miller MA, Summer Chahin PhD, Roger W. Apple PhD, Gautam Saha MD, G. Prasad Rao MD, Afzal Javed FRCPsych
Concepts of suicide are explored in this issue with a focus on suicide in children and adolescents. The epidemiology of pediatric suicide in the United States is reviewed; also, risk and protective factors, as well as prevention strategies, are discussed. Suicide in the pediatric athlete and the potential protective effect of exercise are examined. In addition, this analysis addresses the beneficial
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Role of gene therapy in sickle cell disease Dis Mon (IF 4.0) Pub Date : 2024-02-06 Aishwarya Raghuraman, Rebecca Lawrence, Rudrakshi Shetty, Avanthika Chaithanya, Sharan Jhaveri, Brinela Vivas Pichardo, Amulya Mujakari
Gene therapy is an emerging treatment for sickle cell disease that works by replacing a defective gene with a healthy gene, allowing the body to produce normal red blood cells. This form of treatment has shown promising results in clinical trials, and is a promising alternative to traditional treatments. Gene therapy involves introducing a healthy gene into the body to replace a defective gene. The
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Ovarian tumors in the pediatric population: An update Dis Mon (IF 4.0) Pub Date : 2024-01-28 Berrin Ergun-Longmire, Donald E. Greydanus
Research reveals that 1% of neoplasms in females under 17 years of age are ovarian neoplasms and though usually benign, malignant tumors may occur in the pediatric age group. This review considers various current concepts of these tumors including the epidemiology, risk factors, clinical presentations, diagnosis, differential diagnosis, and treatment options including the need to provide fertility-sparing
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Updates in atopic dermatitis for the primary care physician: A review of advances in the understanding and treatment of atopic dermatitis Dis Mon (IF 4.0) Pub Date : 2024-01-25 Zi-Yi Choo, Stephanie L. Mehlis, Joel C. Joyce
Atopic dermatitis (AD) is a common inflammatory skin condition occurring in both pediatric and adult patients. Pruritus is a clinical hallmark of the disease, and patients with AD often experience disruptions to their quality of life. The pathogenesis of AD is a complex and multifactorial interplay between genetic factors, epidermal barrier disruption, and immune dysregulation. Clinically, AD is characterized
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Foreword for: Ovarian tumors in the pediatric population: An update Dis Mon (IF 4.0) Pub Date : 2024-01-24 Jerrold B. Leikin
Abstract not available
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Foreword for the role of gene therapy in sickle cell disease Dis Mon (IF 4.0) Pub Date : 2024-01-24 Jerrold B. Leikin
Abstract not available
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Foreword: Updates in atopic dermatitis for the primary care physician: A review of advances in the understanding and treatment of atopic dermatitis Dis Mon (IF 4.0) Pub Date : 2024-01-24 Jerrold B Leikin
Abstract not available
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Study the relationship between left atrial (LA) volume and LV diastolic dysfunction and LV hypertrophy: Correlate LA volume with cardiovascular risk factors Dis Mon (IF 4.0) Pub Date : 2024-01-22 Shubhadarshini G. Pawar, Praveen Bharath Saravanan, Shipra Gulati, Shefali Pati, Muskan Joshi, Ajal Salam, Nida Khan
Heart failure (HF) with normal ejection fraction - the isolated diastolic heart failure, depicts increasing prevalence and health care burden in recent times. Having less mortality rate compared to systolic heart failure but high morbidity, it is evolving as a major cardiac concern. With increasing clinical use of Left atrial volume (LAV) quantitation in clinical settings, LAV has emerged as an important
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Gastrointestinal Behçet's disease: Manifestations, diagnosis, and management Dis Mon (IF 4.0) Pub Date : 2024-01-06 Zara Manuelyan, Edward Butt, Sreeram Parupudi
Behçet's disease (BD) is a rare, inflammatory vascular disorder with recurrent oral and genital aphthous ulcers, along with ocular and cutaneous manifestations. Gastrointestinal (GI) BD may involve any portion of the GI tract. However, it is commonly described in the terminal ileum, followed by the ileocecal region. Diagnosis is challenging given lack of pathognomonic tests; therefore, it is based
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Forword for selected topics in pathology of the gastrointestinal tract Dis Mon (IF 4.0) Pub Date : 2024-01-05 Jerrold B. Leikin
Abstract not available
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Factors influencing the quality of life in inflammatory bowel disease: A comprehensive review Dis Mon (IF 4.0) Pub Date : 2023-12-23 Samina Khan, Sneha Annie Sebastian, Mihirkumar P. Parmar, Nitin Ghadge, Inderbir Padda, Ahmed S. Keshta, Naofel Minhaz, Apurva Patel
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Navigating the path of TOF- A Literature review unveiling maternal-fetal dynamics, treatment strategies and psychological dimensions Dis Mon (IF 4.0) Pub Date : 2023-11-10 Poulami Roy, Viraj Sah, Novonil Deb, Vikash Jaiswal
Tetralogy of Fallot (TOF) is a complex congenital heart defect that poses unique challenges for both mothers and their unborn children. This comprehensive review, titled aims to provide a holistic exploration of the maternal-fetal dynamics, treatment strategies, and psychological dimensions involved in navigating the path of TOF during pregnancy. It delves into the physiological changes that occur
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The association of Pulmonary Hypertension and right ventricular systolic function –updates in diagnosis and treatment Dis Mon (IF 4.0) Pub Date : 2023-09-19 Shubhadarshini G. Pawar, Nida Khan, Ajal Salam, Muskan Joshi, Praveen Bharath Saravanan, Shreya Pandey
Right ventricular (RV) systolic function is an essential but neglected component in cardiac evaluation, and its importance to the contribution to overall cardiac function is undermined. It is not only sensitive to the effect of left heart valve disease but is also more sensitive to changes in pressure overload than the left ventricle. Pulmonary Hypertension is the common and well-recognized complication
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Gene therapy for heart failure: A novel treatment for the age old disease Dis Mon (IF 4.0) Pub Date : 2023-09-19 Neel Vora, Parth Patel, Aarsh Gajjar, Parva Ladani, Ashwati Konat, Devanshi Bhanderi, Srikanth Gadam, Priyadarshi Prajjwal, Kamal Sharma, Shivaram Poigai Arunachalam
Across the globe, cardiovascular disease (CVD) is the leading cause of mortality. According to reports, around 6.2 million people in the United states have heart failure. Current standards of care for Heart Failure can delay but not prevent progression of disease. Gene therapy is one of the novel treatment modalities that promises to fill this limitation in the current standard of care for Heart Failure
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Health equity in pediatrics: Current concepts for the care of children in the 21st century (Dis Mon) Dis Mon (IF 4.0) Pub Date : 2023-09-20 Cheryl A. Dickson MD MPH, Berrin Ergun-Longmire MD, Donald E. Greydanus MD DrHC (Athens), Ransome Eke MD PhD, Bethany Giedeman BS, Nikoli M. Nickson BA, Linh-Nhu Hoang MA, Uzochukwu Adabanya MD MPH, Daniela V. Pinto Payares BS MS, Summer Chahin PhD, Jerica McCrary BS MPA, Katie White MA, Jin Hyung Moon BS, Nizoramo Haitova PhD, Jocelyn Deleon MD, Roger W. Apple PhD
This is an analysis of important aspects of health equity in caring for children and adolescents written by a multidisciplinary team from different medical centers. In this discussion for clinicians, we look at definitions of pediatric health equity and the enormous impact of social determinants of health in this area. Factors involved with pediatric healthcare disparities that are considered include
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Foreword: Clinical issues in cardiology Dis Mon (IF 4.0) Pub Date : 2023-09-16 Jerrold B. Leikin
Abstract not available
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Myopathies of endocrine origin: A review for physicians Dis Mon (IF 4.0) Pub Date : 2023-09-16 Devarsh N. Shah, Harshal Prakash Chorya, N. Nishitha Ramesh, Sulochana Gnanasekaram, Neil Patel, Yashendra Sethi, Nirja Kaka
Myopathies are a common manifestation of endocrine disorders. Endocrine myopathies are often overlooked while considering differential diagnoses in patients with musculoskeletal symptoms. The hindrance to mobility and the musculoskeletal discomfort owing to these myopathies are important causes of disability and depreciated quality of life in these patients. Endocrine myopathies occur due to the effects
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Updates in the management of atrial fibrillation: Emerging therapies and treatment Dis Mon (IF 4.0) Pub Date : 2023-09-15 Saud Muthanna Shakir Al-Ezzi, Isha Bista, Mohammed Muthanna Al-Ezzi, Priyadarshi Prajjwal, Safa Muthanna Shakir Al-Ezzi, Himani Harshad Pattani, Bita Amiri, Mohammed Dheyaa Marsool Marsool
Objective The most common and clinically important cardiac arrhythmia is atrial fibrillation (AF), which has a large negative impact on the public's health due to higher fatalities, morbidity, and healthcare expenditure rates. This study aims to provide valuable insights into the effectiveness and outcomes of various treatment approaches and interventions for AF. Study design Systematic review. Method
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Heart Failure: Recent Advances and Breakthroughs Dis Mon (IF 4.0) Pub Date : 2023-09-12 Sneha Annie Sebastian, Edzel Lorraine Co, Arun Mahtani, Inderbir Padda, Mahvish Anam, Swapna Susan Mathew, Ayesha Shahzadi, Maha Niazi, Shubhadarshini Pawar, Gurpreet Johal
Heart failure (HF) is a common clinical condition encountered in various healthcare settings with a vast socioeconomic impact. Recent advancements in pharmacotherapy have led to the evolution of novel therapeutic agents with a decrease in hospitalization and mortality rates in HF with reduced left ventricular ejection fraction (HFrEF). Lately, the introduction of artificial intelligence (AI) to construct
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Foreword: Musculoskeletal disorders in elite athletes and endocrine – induced myopathies Dis Mon (IF 4.0) Pub Date : 2023-09-15 Jerrold B. Leikin
Abstract not available
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Prevalence, diagnosis and management of musculoskeletal disorders in elite athletes: A mini-review Dis Mon (IF 4.0) Pub Date : 2023-09-15 Carlos Romero-Morales, Daniel López-López, Jaime Almazán-Polo, Sara Mogedano-Cruz, María Dolores Sosa-Reina, Guillermo García-Pérez-de-Sevilla, Sebastián Martín-Pérez, Ángel González-de-la-Flor
Musculoskeletal injuries in elite sports are ones of the most impact issue because their remarkable impact on performance caused by drastic absence of training and competition and a progressive deterioration in physical health, emotional and social athletes' dimensions. Also, the prevalence of epidemiologic research found an incidence of musculoskeletal disorders vary within sports and in elite athletes
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Foreword: Health equity in pediatrics: Current concepts for the care of children in the 21st century Dis Mon (IF 4.0) Pub Date : 2023-09-14 Jerrold B. Leikin MD
Abstract not available
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Tachy-brady syndrome: Electrophysiology and evolving principles of management Dis Mon (IF 4.0) Pub Date : 2023-09-09 Inderbir Padda, Sneha Annie Sebastian, Nimrat Khehra, Arun Mahtani, Yashendra Sethi, Venkatesh Panthangi, Matthew Fulton, Dhrubajyoti Bandyopadhyay, Gurpreet Johal
Sudden alterations in the heart rate may be associated with diverse symptoms. Sinus node dysfunction (SND), also known as sick sinus syndrome, is a sinoatrial (SA) node disorder. SND is primarily caused by the dysfunction of the pacemaker, as well as impaired impulse transmission resulting in a multitude of abnormalities in the heart rhythms, such as bradycardia-tachycardia, atrial bradyarrhythmias
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Ulcerative colitis: Addressing the manifestations, the role of fecal microbiota transplantation as a novel treatment option and other therapeutic updates Dis Mon (IF 4.0) Pub Date : 2023-06-24 Mohammed Dheyaa Marsool Marsool, Neel Vora, Ali Dheyaa Marsool Marsool, Shefali Pati, Manasi Narreddy, Parth Patel, Srikanth Gadam, Priyadarshi Prajjwal
The prevalence and incidence of Ulcerative Colitis (UC), a recurrent and remitting inflammatory condition, are rising. Any part of the colon may be affected, beginning with inflammation of the mucosa in the rectum and continuing proximally continuously. Bloody diarrhea, tenesmus, fecal urgency, and stomach pain are typical presenting symptoms. Many patients present with extraintestinal manifestations
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