-
Thoracoscopic Intercostal Nerve Block with Cocktail Analgesics for Pain Control After Video-Assisted Thoracoscopic Surgery: A Prospective Cohort Study J. Pain Res. (IF 2.7) Pub Date : 2024-03-18 Jue Li, Yingxian Dong, Jiawei Guo, Lei Wang, Jie Tian, Li Wang, Guowei Che
Objective: To evaluate whether using a cocktail of intercostal nerve blocks (TINB) during thoracoscopic surgery results in better clinical outcomes than patient-controlled analgesia (PCIA). Methods: Patients in two medical groups undergoing video-assisted thoracoscopic surgery (VATS) for pulmonary nodules in West China Hospital of Sichuan University were collected consecutively between March 2022 and
-
Perspective on Intradiscal Therapies for Lumbar Discogenic Pain: State of the Science, Knowledge Gaps, and Imperatives for Clinical Adoption J. Pain Res. (IF 2.7) Pub Date : 2024-03-18 Morgan P Lorio, Jordan Lee Tate, Thomas J Myers, Jon E Block, Douglas P Beall
Abstract: Specific clinical diagnostic criteria have established a consensus for defining patients with lumbar discogenic pain. However, if conservative medical management fails, these patients have few treatment options short of surgery involving discectomy often coupled with fusion or arthroplasty. There is a rapidly-emerging research effort to fill this treatment gap with intradiscal therapies that
-
A Data Mining Study for Analysis of Acupoint Selection and Combinations in Acupuncture Treatment of Carpal Tunnel Syndrome J. Pain Res. (IF 2.7) Pub Date : 2024-03-18 Yujun He, Furui Miao, Cai He, Yushan Fan, Fangzhi Zhang, Pu Yang, Miaodong Wang, Jiujie He
Background: Carpal tunnel syndrome (CTS) is the most prevalent upper limb compressive neuropathy. A considerable number of clinical trials and meta-analyses have provided evidence supporting the effectiveness of acupuncture in treating CTS. Nevertheless, the ideal choice of acupoints remains ambiguous. Objective: A data mining analysis was conducted with the objective of determining the most effective
-
The New Orientation of Postoperative Analgesia: Remote Ischemic Preconditioning J. Pain Res. (IF 2.7) Pub Date : 2024-03-18 Yunyu Xiao, Shaofeng Zhang, Qiusheng Ren
Purpose of Review: Postoperative analgesia is currently a significant topic in anesthesiology. Currently, the predominant approach for achieving multimodal analgesia involves the utilization of pharmacotherapy and regional anesthesia procedures. The primary objectives of this approach are to mitigate postoperative pain, enhance patient satisfaction, and diminish overall opioid usage. Nevertheless,
-
Identifying Risk Factors for Cardiovascular Events Among Active-Duty Service Members and Veterans Prescribed Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) J. Pain Res. (IF 2.7) Pub Date : 2024-03-15 Whitney L Forbes, Justin Petway, Laura E Gressler, Hannah Thorfinnson, Ryan C Costantino, Timothy J Atkinson
Background: Oral NSAIDs are widely used analgesic medications for the treatment of musculoskeletal and inflammatory conditions. NSAIDs are associated with adverse effects that arise from COX enzyme inhibition including cardiovascular events. The combined role of patient and prescription factors associated with NSAID use on cardiovascular risk is not well characterized. Objective: The purpose of this
-
Efficacy of Acupuncture-Related Therapy for Migraine: A Systematic Review and Network Meta-Analysis J. Pain Res. (IF 2.7) Pub Date : 2024-03-15 Yinqin Liu, Yan Wang, Chuanhao Mi, Ziyue Wang, Yu Han, Xianghua Qi, Xiao Ding
Objective: Migraine is a common neurological disorder, which resulting in significant societal and personal burdens. Acupuncture has attracted widespread attention in migraine prophylaxis and treatment in recent years. Although some studies have confirmed the effectiveness of acupuncture therapy in treating migraines, there is still a lack of comprehensive evaluation regarding the comparison between
-
Looking for a Beam of Light to Heal Chronic Pain J. Pain Res. (IF 2.7) Pub Date : 2024-03-16 Jialing Xu, Hao Zhang, Dan Chen, Kaiyong Xu, Zifa Li, Hongyun Wu, Xiwen Geng, Xia Wei, Jibiao Wu, Wenqiang Cui, Sheng Wei
Abstract: Chronic pain (CP) is a leading cause of disability and a potential factor that affects biological processes, family relationships, and self-esteem of patients. However, the need for treatment of CP is presently unmet. Current methods of pain management involve the use of drugs, but there are different degrees of concerning side effects. At present, the potential mechanisms underlying CP are
-
The Clinical Efficacy of Platelet-Rich Plasma Injection Therapy versus Different Control Groups for Chronic Low Back Pain: A Network Meta-Analysis of Randomized Controlled Trials J. Pain Res. (IF 2.7) Pub Date : 2024-03-14 Xue Zhang, Aili Zhang, Hao Guan, Li Zhou, Jiao Zhang, Wenjie Yin
Objective: Low back pain is one of the main causes of disability in the world. Although regenerative medicine may represent breakthroughs in the management of low back pain, its use remains controversial. Therefore, we conducted a meta-analysis to evaluate the clinical efficacy of platelet-rich plasma (PRP) injection therapy versus different control groups for chronic low back pain during 4 weeks,
-
Nociceptive Flexion Reflex Threshold is No Suitable Marker for Diagnosing Opioid-Induced Hyperalgesia J. Pain Res. (IF 2.7) Pub Date : 2024-03-14 Luisa Trübenbacher, Nicole Lindenberg, Bernhard M Graf, Markus Backmund, Wilhelm Unglaub, Christoph L Lassen
Background: Opioid induced hyperalgesia (OIH) describes a state of altered pain sensation due to opioid exposure. It often occurs among persons with opioid use disorder receiving substitution therapy. Methods: The purpose of this study was to find out, whether OIH diagnosis could be facilitated by an objective pain indicating marker: the Nociceptive Flexion Reflex (NFR). Forty persons with opioid use
-
Pain Comorbidities with Attention Deficit: A Narrative Review of Clinical and Preclinical Research J. Pain Res. (IF 2.7) Pub Date : 2024-03-14 Hong-Bin Liang, Wan-You He, Yan-Ping Liu, Han-Bing Wang
Abstract: A negative correlation exists between attention and pain. The cognitive impairments linked to pain can significantly impede a patient’s healing process and everyday tasks, particularly for individuals experiencing persistent pain. Furthermore, it has been demonstrated that diversion can effectively decrease pain levels in individuals. The focus of this review is to analyze clinical trials
-
Dry Needling with the Use of FRSc Technique in Addition to Standard Rehabilitation Program for Chronic Low Back Pain: A Randomized Controlled Trial Using Both PROMs and Measurement Tools J. Pain Res. (IF 2.7) Pub Date : 2024-03-13 Joanna Rajfur, Katarzyna Rajfur, Tomasz Matusz, Maria Malarska, Karolina Walewicz, Kuba Ptaszkowski, Robert Dymarek, Jakub Taradaj
Purpose: Dry needling (DN) has gained popularity for musculoskeletal conditions, but its commercial use often surpasses scientific evidence. The novel Five Regulatory Systems Concept (FRSc) of DN shows potential therapeutic mechanisms, including chronic low back pain (LBP). However, rigorous clinical assessment with patient-reported outcome measures (PROMs) and objective measures are necessary. This
-
Bone Cements Used in Vertebral Augmentation: A State-of-the-art Narrative Review J. Pain Res. (IF 2.7) Pub Date : 2024-03-13 Tyree D Williams, Talia Adler, Lindsey Smokoff, Anmoldeep Kaur, Benjamin Rodriguez, Kavita Jyoti Prakash, Edib Redzematovic, Turner S Baker, Benjamin I Rapoport, Edward S Yoon, Douglas P Beall, Jonathan S Dordick, Reade A De Leacy
Abstract: Vertebral compression fractures (VCFs) are common in osteoporotic patients, with a frequency projected to increase alongside a growing geriatric population. VCFs often result in debilitating back pain and decreased mobility. Cement augmentation, a minimally invasive surgical technique, is widely used to stabilize fractures and restore vertebral height. Acrylic-based cements and calcium phosphate
-
Update on Treating Painful Diabetic Peripheral Neuropathy: A Review of Current US Guidelines with a Focus on the Most Recently Approved Management Options J. Pain Res. (IF 2.7) Pub Date : 2024-03-13 Theresa Mallick-Searle, Jeremy A Adler
Abstract: Painful diabetic peripheral neuropathy (DPN) is a highly prevalent and disabling complication of diabetes that is often misdiagnosed and undertreated. The management of painful DPN involves treating its underlying cause via lifestyle modifications and intensive glucose control, targeting its pathogenesis, and providing symptomatic pain relief, thereby improving patient function and health-related
-
Contact-Heat Evoked Potentials: Insights into Pain Processing in CRPS Type I J. Pain Res. (IF 2.7) Pub Date : 2024-03-13 Florin Allmendinger, Paulina Simonne Scheuren, Iara De Schoenmacker, Florian Brunner, Jan Rosner, Armin Curt, Michèle Hubli
Purpose: The pathophysiological mechanisms underlying the development of chronic pain in complex regional pain syndrome (CRPS) are diverse and involve both peripheral and central changes in pain processing, such as sensitization of the nociceptive system. The aim of this study was to objectively distinguish the specific changes occurring at both peripheral and central levels in nociceptive processing
-
Novel Implantation Technique for Thoracoabdominal Peripheral Nerve Stimulation via a Transversus Abdominal Plane Approach for Treatment of Chronic Abdominal Pain J. Pain Res. (IF 2.7) Pub Date : 2024-03-12 Christopher M Lam, Sarah A Keim, Dawood Sayed, Alaa Abd-Elsayed, Amitabh Gulati, Michael E Schatman, Timothy Deer, Usman Latif
Background: Chronic abdominal pain (CAP) is a common and challenging to treat condition with a global prevalence of up to 25%. Despite extensive evaluation, approximately 40% of patients with CAP have an unknown diagnosis. Medications may be ineffective, and surgery is rarely indicated. Interventional treatment including sympathetic blocks, sympathetic neurolysis, and transversus abdominal plane (TAP)
-
Chronic Abdominal Discomfort Syndrome (CADS): Defining and Discussing a Novel Diagnosis J. Pain Res. (IF 2.7) Pub Date : 2024-03-11 Mayank Gupta, Anand S Patil, Ahish Chitneni, Michael E Schatman, Hemant Kalia, Timothy R Deer, Dawood Sayed, Amol Soin, Ganesan Baranidharan, Peter Staats, Leonardo Kapural, Phani Ashok Attaluri, Paul Verrills, Sudhir Diwan, Danielle Levin, Nimisha Halder, Alaa A Abd-Elsayed
Abstract: In this article, we propose a new diagnostic paradigm known as Chronic Abdominal Discomfort Syndrome (CADS). Patient’s presentation centers around chronic abdominal pain not explained by acute pathology with or without accompanying dyspepsia, bloating, nausea and vomiting among other symptoms. The pathophysiology is noted to be neurogenic, possibly stemming from visceral sympathetic nerves
-
Scoping Review: The Role of Psychedelics in the Management of Chronic Pain J. Pain Res. (IF 2.7) Pub Date : 2024-03-11 Christopher L Robinson, Alexandra CG Fonseca, Efemena M Diejomaoh, Ryan S D'Souza, Michael E Schatman, Vwaire Orhurhu, Trent Emerick
Introduction: Amid a lack of effective chronic pain treatments, psychedelics have gained attention as a potential solution, although their Schedule 1 classification poses challenges. Psychedelics, such as lysergic acid diethylamide (LSD) and psilocybin, have gained popularity as alternatives and adjuncts for chronic pain treatment. Studies suggest that they may modulate pain processing through agonism
-
Expert Consensus on Ion Channel Drugs for Chronic Pain Treatment in China J. Pain Res. (IF 2.7) Pub Date : 2024-03-08 Ke Ma, Zhixiang Cheng, Hao Jiang, Zhangya Lin, Chuansheng Liu, Xianguo Liu, Lijuan Lu, Yan Lu, Wei Tao, Suoliang Wang, Xiaoqiu Yang, Qishan Yi, Xiaomei Zhang, Ying Zhang, Yanqing Liu
Abstract: Ion channel drugs have been increasing used for chronic pain management with progress in the development of selective calcium channel modulators. Although ion channel drugs have been proven safe and effective in clinical practice, uncertainty remains regarding its use to treat chronic pain. To standardize the clinical practice of ion channel drug for the treatment of chronic pain, the National
-
Are There Any Advantages of the Low Opioid Anaesthesia and Non-Opioid Postoperative Analgesia Protocol: A Clinical Observational Study J. Pain Res. (IF 2.7) Pub Date : 2024-03-08 Urszula Kościuczuk, Katarzyna Tarnowska, Ewa Rynkiewicz-Szczepanska
Purpose: The methods of perioperative analgesia and pain control have changed. The principle of opioid-based analgesia has been modified to multimodal analgesia, followed by LOA (low opioid anaesthesia) and OFA (opioid-free anaesthesia). The aim was to describe the effects of LOA on nausea, vomiting, and pain control during general anaesthesia and postoperative period after laparoscopic cholecystectomy
-
Effect of Intermittent Thoracic Paravertebral Block on Postoperative Nausea and Vomiting Following Thoracoscopic Radical Resection of the Lung Cancer: A Prospective Randomized Trial J. Pain Res. (IF 2.7) Pub Date : 2024-03-07 Ting Ma, Yulong Yu, Haihua Cao, Huiqin Wang, Mingcang Wang
Purpose: To explore the benefits of ultrasound-guided intermittent thoracic paravertebral block (TPVB) combined with intravenous analgesia (PCIA) in alleviating postoperative nausea and vomiting (PONV) during video-assisted thoracic surgery (VATS). Patients and Methods: 120 patients with lung carcinoma undergoing VATS were included and divided into three groups: group S (single TPVB+PCIA), group I
-
Reviewing the Potential Role of Artificial Intelligence in Delivering Personalized and Interactive Pain Medicine Education for Chronic Pain Patients J. Pain Res. (IF 2.7) Pub Date : 2024-03-06 Christopher L Robinson, Ryan S D'Souza, Cyrus Yazdi, Efemena M Diejomaoh, Michael E Schatman, Trent Emerick, Vwaire Orhurhu
Abstract: The integration of artificial intelligence (AI) in patient pain medicine education has the potential to revolutionize pain management. By harnessing the power of AI, patient education becomes more personalized, interactive, and supportive, empowering patients to understand their pain, make informed decisions, and actively participate in their pain management journey. AI tailors the educational
-
Long-Term Follow-Up of Ultrasound-Guided Glossopharyngeal Nerve Block Treatment for Glossopharyngeal Neuralgia: A Retrospective Clinical Study of 43 Cases J. Pain Res. (IF 2.7) Pub Date : 2024-03-06 Shaohua You, Xiaoyan Qin, Li Tong, Zeguo Feng
Background: Glossopharyngeal neuralgia (GPN) is a rare chronic neuropathic pain disorder that significantly impacts quality of life. Ultrasound-guided glossopharyngeal nerve blocks (UGPNB) have gained popularity due to their various advantages. However, there have been no studies reporting the long-term outcomes of UGPNB in a larger cohort of GPN patients. Aim: This study aims to evaluate the efficacy
-
Pharmacopuncture Therapy as an Adjunctive Treatment for Patients with Lumbar Spinal Stenosis: A Pragmatic Randomized Controlled Pilot Trial J. Pain Res. (IF 2.7) Pub Date : 2024-03-06 Yoona Oh, Chang-Hyun Han, Yeonhak Kim, Jihun Kim, Changsop Yang, Young Eun Choi, Byoung-Kab Kang, Kun Hyung Kim, Gi Young Yang, Byung Ryul Lee, Eunseok Kim
Purpose: Pharmacopuncture therapy (PPT) combines medicinal extracts with acupuncture and is widely used as an adjunct in clinical practice. This study assessed the safety and feasibility of PPT in addition to conventional Korean Medicine treatment (CKMT), including electroacupuncture, cupping and infra-red, for lumbar spinal stenosis (LSS). Patients and Methods: Forty patients diagnosed with LSS were
-
Pulsed Radiofrequency 2 Hz Preserves the Dorsal Root Ganglion Neuron Physiological Ca2+ Influx, Cytosolic ATP Level, Δψm, and pERK Compared to 4 Hz: An Insight on the Safety of Pulsed Radiofrequency in Pain Management [Response to Letter] J. Pain Res. (IF 2.7) Pub Date : 2024-03-05 Ristiawan Muji Laksono, Taufiq Agus Siswagama, Fa'urinda Riam Prabu Nery, Walter van der Weegen, Willy Halim
Response to Letter in regards to Pulsed Radiofrequency 2 Hz Preserves the Dorsal Root Ganglion Neuron Physiological Ca2+ Influx, Cytosolic ATP Level, Δψm, and pERK Compared to 4 Hz: An Insight on the Safety of Pulsed Radiofrequency in Pain Management [Letter]
-
Acupoint Selection in Postoperative Ophthalmic Pain Management: A Data Mining Protocol J. Pain Res. (IF 2.7) Pub Date : 2024-03-05 Jing Wang, Feng Yang, Xing Wang, Fang Pang
Background: Postoperative ophthalmic pain not only induces anxiety and depression among patients, but also prolongs the recovery cycle. However, the management of postoperative pain in ophthalmology is still not standardized. The effectiveness of acupuncture in treating postoperative pain has been validated based on numerous clinical trials and meta-analysis. Our study is to conduct the first data
-
Humoral Cytokine Levels in Patients with Herpes Zoster: A Meta-Analysis J. Pain Res. (IF 2.7) Pub Date : 2024-03-05 Jiayu Yue, Ming Yao
Background: The neurocutaneous disease caused by the reactivation of varicella-zoster virus (VZV) is called herpes zoster (HZ). The virus remains in the spinal cord back root after the chickenpox disappears. Diminished immune function can reactivate VZV, causing severe neuropathic pain that can last for months or even years, leading to postherpetic neuralgia (PHN), which severely affects the patient’s
-
Opioid Use Disorder: A Qualitative Exploratory Analysis of Potential Misunderstandings in Patients with Chronic Non-Cancer Pain J. Pain Res. (IF 2.7) Pub Date : 2024-03-05 Neele Kufeld, Klaus Weckbecker, Johannes Michalak, Winfried Häuser, Frank Petzke, Norbert Scherbaum, Michael Specka, Alexandra Schmidt, Alexandra Piotrowski, Christine Kersting, Johannes Maximilian Just
Purpose: Substance use disorders (SUD) are a challenging comorbidity in patients with chronic non-cancer pain (CNCP) as they complicate diagnosis and therapy, especially when opioids are part of the therapeutic regimen. A definite diagnosis of opioid use disorder (OUD) in patients with CNCP on long-term opioid therapy (LTOT) is a prerequisite for effective and targeted therapy but may be complicated
-
Characteristic Behaviors of Pain During Movement in the Older Individuals with Dementia J. Pain Res. (IF 2.7) Pub Date : 2024-03-05 Kenta Nakada, Kazuhiro Shimo, Satoshi Ohga, Takako Matsubara
Purpose: This study assessed the pain associated with movement and exercise in older individuals with cognitive decline, using the Abbey Pain Scale (APS) to identify the sub-items that effectively reflect pain during such activities. Patients and Methods: A cross-sectional study was conducted in 225 older patients with musculoskeletal disorders and cognitive decline at the Ikeda Rehabilitation Hospital
-
Efficacy and Safety of High-Voltage Pulsed Radiofrequency versus Standard-Voltage Pulsed Radiofrequency for Patients with Neuropathic Pain: A Literature Review and Meta-Analysis J. Pain Res. (IF 2.7) Pub Date : 2024-03-04 Yu Wang, Yitong Jia, Zheng Wang, Guang Feng, Yanhui Ma, Zhen Fan, Miao Liu, Kunpeng Feng, Tianlong Wang
Background: Neuropathic pain (NP) is recognized as one of the most difficult pain syndromes which lacks a safe, well-tolerated and effective treatment. Pulsed radiofrequency (PRF), a novel and minimally invasive interventions, has been introduced to alleviate various types of NP. Previous studies reported PRF with higher voltage could further improve the treatment efficacy. Therefore, we conducted
-
Shifts in Students’ Attitudes Towards Pain Patients, Pain, and Opioid Management Following a Dedicated Medical School Pain Curriculum J. Pain Res. (IF 2.7) Pub Date : 2024-03-02 Shravani Durbhakula, Tony Y Wang, Kara G Segna, Gerard R Limerick, Mustafa Y Broachwala, Michael E Schatman, Munfarid A Zaidi, Ingharan James Siddarthan, Serkan Toy
Objective: To examine the immediate effects of a comprehensive pain course on medical students’ pre-existing perceptions and attitudes toward pain patients and opioid management. Methods: First-year medical students at a major academic medical center enrolled in a required pre-clerkship pain course in June 2020 and completed pre- and post-course online surveys with Likert-scale questions about their
-
The Emotion Regulation of Acupuncture in Chronic Low Back Pain: A Clinical Neuroimaging Protocol J. Pain Res. (IF 2.7) Pub Date : 2024-03-01 Peng Lai, Shirui Cheng, Xingyao Chen, Fangdong Cheng, Jun Cheng, Ming Xin, Deliang Zhu, Zhengjie Li, Xi Wu, Fang Zeng
Introduction: Acupuncture is effective for patients with chronic low back pain (CLBP), which can relieve pain intensity and regulate negative emotional states such as pain-related anxiety and depression. Previous studies mainly discuss the analgesic mechanism of acupuncture treatment of CLBP, but there are multiple dimensions to pain, including sensation, emotion and cognition. Therefore, this study
-
Knowledge Mapping Analysis of Research on Pregnancy-Related Pelvic Girdle Pain (PPGP) from 2002 to 2022 Using Bibliometrics [Corrigendum] J. Pain Res. (IF 2.7) Pub Date : 2024-03-01 Linli Xu, Yuanchao Li, Yanan He, Mengtong Chen, Yuting Zhang, Chunlong Liu, Li Zhang
-
Multimodal Acute Pain Management in the Parturient with Opioid Use Disorder: A Review J. Pain Res. (IF 2.7) Pub Date : 2024-02-29 Victor Koltenyuk, Ismat Mrad, Ian Choe, Mohamad Ibrahim Ayoub, Sangeeta Kumaraswami, Jeff L Xu
Abstract: The opioid epidemic in the United States has led to an increasing number of pregnant patients with opioid use disorder (OUD) presenting to obstetric units. Caring for this complex patient population requires an interdisciplinary approach involving obstetricians, anesthesiologists, addiction medicine physicians, psychiatrists, and social workers. The management of acute pain in the parturient
-
The Association Between Orofacial Pain and Depression: A Systematic Review J. Pain Res. (IF 2.7) Pub Date : 2024-02-29 Hadia Anita, Farah Asnely Putri, Tantry Maulina
Background: The occurrence of orofacial pain is often accompanied by comorbid conditions such as depression. Even though previous studies suggested a bidirectional correlation between orofacial pain and psychological factors, some studies still provided contradictory results. Objective: This systematic review aimed at providing scientific evidence regarding the association between orofacial pain and
-
Acupuncture-Related Therapy for Knee Osteoarthritis: A Narrative Review of Neuroimaging Studies J. Pain Res. (IF 2.7) Pub Date : 2024-02-27 Yuzhu Qu, Ying Peng, Yan Xiong, Xiaohui Dong, Peihong Ma, Shirui Cheng
Abstract: Acupuncture has been widely applied for treating knee osteoarthritis (KOA). Numerous studies have found that acupuncture can effectively alleviate KOA symptoms. With the advancement of neuroimaging techniques, integrating neuroimaging with in-depth investigations of acupuncture mechanisms has emerged as a hot topic in traditional Chinese medical neuroscience research. This review aimed to
-
Pulsed Radiofrequency 2 Hz Preserves the Dorsal Root Ganglion Neuron Physiological Ca2+ Influx, Cytosolic ATP Level, Δψm, and pERK Compared to 4 Hz: An Insight on the Safety of Pulsed Radiofrequency in Pain Management [Letter] J. Pain Res. (IF 2.7) Pub Date : 2024-02-27 Marc Russo
Letter for the article Pulsed Radiofrequency 2 Hz Preserves the Dorsal Root Ganglion Neuron Physiological Ca2+ Influx, Cytosolic ATP Level, Δψm, and pERK Compared to 4 Hz: An Insight on the Safety of Pulsed Radiofrequency in Pain Management
-
Endoscopic Revision Strategies and Outcomes for Recurrent L4/5 Disc Herniation After Percutaneous Endoscopic Transforaminal Discectomy J. Pain Res. (IF 2.7) Pub Date : 2024-02-23 Antao Lin, Yan Wang, Hao Zhang, Kai Zhu, Dan Zhou, Jianwei Guo, Wenhao Zhao, Chuanli Zhou, Xuexiao Ma
Objective: We explore the endoscopic revision and surgical techniques for L4/5 recurrent disc herniation (rLDH) after percutaneous endoscopic transforaminal discectomy (PETD). Methods: A retrospective study was conducted. From January 2016 to September 2022, 96 patients who underwent percutaneous endoscopic lumbar discectomy for L4/5 rLDH after PETD were enrolled in the study. Based on the revision
-
Clinical Outcomes of Percutaneous Transforaminal Endoscopic Discectomy Assisted with Selective Nerve Root Block for Treating Radicular Pain with Diagnostic Uncertainty in the Elderly J. Pain Res. (IF 2.7) Pub Date : 2024-02-20 Yanjie Zhu, Xinkun Zhang, Guangfei Gu, Yunshan Fan, Zhi Zhou, Chaobo Feng, Xin Gu, Shisheng He
Purpose: To investigate the clinical outcomes of percutaneous transforaminal endoscopic discectomy assisted with selective nerve root block for treating radicular pain with diagnostic uncertainty in the elderly. Methods: A total number of 36 elderly patients were included in the study. Clinical outcomes collected for analysis include operative time, hospital stay time, Visual Analog Scale, and Oswestry
-
Investigating the Impact of Stress on Pain: A Scoping Review on Sense of Control, Social-Evaluative Threat, Unpredictability, and Novelty (STUN Model) J. Pain Res. (IF 2.7) Pub Date : 2024-02-20 Karen Ghoussoub, Catherine Isadora Côté, Maude Fortier, Bénédicte Nauche, Pierre Rainville, M Gabrielle Pagé
Background: Stress can have paradoxical effects on pain, namely hyperalgesia and hypoalgesia. Four situational characteristics activate the hypothalamic–pituitary–adrenal axis, leading to a physiological stress response: lacking Sense of control, social-evaluative Threat, Unpredictability and Novelty (STUN). This scoping review reports on the types of evidence published on the effects of STUN characteristics
-
Spinal Cord Stimulation for Intractable Visceral Pain Originating from the Pelvic and Abdominal Region: A Narrative Review on a Possible New Indication for Patients with Therapy-Resistant Pain J. Pain Res. (IF 2.7) Pub Date : 2024-02-19 Matthanja Bieze, Annelotte Pauline van Haaps, Leonardo Kapural, Sean Li, Kris Ferguson, Ralph de Vries, Michael E Schatman, Velja Mijatovic, Jan Willem Kallewaard
Aim: Visceral pain, characterized by pain that is diffuse and challenging to localize, occurs frequently and is difficult to treat. In cases where the pain becomes intractable despite optimal medical management, it can affect patients’ Quality of Life (QoL). Spinal Cord Stimulation (SCS) has emerged as a potential solution for intractable visceral pain. Purpose: In this narrative review, we collected
-
Post-Doctoral Training in Pain Medicine: Too Little, Yet Not Too Late? J. Pain Res. (IF 2.7) Pub Date : 2024-02-19 Scott G Pritzlaff, Miles Day, Sayed E Wahezi, Michael E Schatman
Post-Doctoral Training in Pain Medicine: Too Little, Yet Not Too Late?
-
Effect of Pericapsular Nerve Group Block with Different Concentrations and Volumes of Ropivacaine on Functional Recovery in Total Hip Arthroplasty: A Randomized, Observer-Masked, Controlled Trial J. Pain Res. (IF 2.7) Pub Date : 2024-02-14 Ying Huang, Yao Lu, Jun Wang, Qiang Lu, Hai-Feng Bao, Lang Liu, Chun-Shan Dong
Purpose: The pericapsular nerve group (PENG) block provides satisfactory postoperative analgesia without hampering motor function for total hip arthroplasty (THA); however, unexpected motor block has been observed clinically. It is unknown whether this motor block is related to the dose of ropivacaine. We aimed to conduct a prospective randomized trial to test whether reducing the volume or concentration
-
Effect of Best Practice Alert (BPA) on Post-Discharge Opioid Prescribing After Minimally Invasive Hysterectomy: A Quality Improvement Study J. Pain Res. (IF 2.7) Pub Date : 2024-02-14 Alexandra Jankulov, Sawsan As-Sanie, Christopher Zimmerman, Jessica Virzi, Sudharsan Srinivasan, Hae Mi Choe, Chad M Brummett
Purpose: The aim of this study was to describe the effectiveness of an electronic health record best practice alert (BPA) in decreasing gynecologic post-discharge opioid prescribing following benign minimally invasive hysterectomy. Patients and Methods: The BPA triggered for opioid orders > 15 tablets. Prescribers’ options included (1) decrease to 15 ≤ tablets; (2) remove the order/utilize a defaulted
-
Knowledge Mapping Analysis of Research on Pregnancy-Related Pelvic Girdle Pain (PPGP) from 2002 to 2022 Using Bibliometrics J. Pain Res. (IF 2.7) Pub Date : 2024-02-13 Linli Xu, Yuanchao Li, Yanan He, Mengtong Chen, Yuting Zhang, Chunlong Liu, Li Zhang
Background: Pregnancy-related Pelvic Girdle Pain (PPGP) is a prevalent condition characterized by various physiological and pathological processes in the female body. The objective of this study is to offer a comprehensive understanding of the current research landscape, key areas of interest, and potential future directions in the field of PPGP. Methods: Using Web of Science, we explored PPGP literature
-
TEDOFA Trial Study Protocol: A Prospective Double-Blind, Randomized, Controlled Clinical Trial Comparing Opioid-Free versus Opioid Anesthesia on the Quality of Postoperative Recovery and Chronic Pain in Patients Receiving Thoracoscopic Surgery J. Pain Res. (IF 2.7) Pub Date : 2024-02-12 Bijia Song, Xiuliang Li, Jiguang Yang, Wenjing Li, Lei Wan
Introduction: Seeking effective multimodal analgesia and anesthetic regimen is the basis for the success of ERAS. Opioid-free anesthesia (OFA) is a multimodal anesthesia associating hypnotics, N-methyl-D-aspartate (NMDA) antagonists, local anesthetics, anti-inflammatory drugs and α-2 agonists. Although previous studies have confirmed that OFA is safe and feasible for VATS surgery, there is great heterogeneity
-
Exacerbation of Pre-Existing Chronic Pain in Older Adults After SARS-CoV-2 Infection: A Single-Center, Cross-Sectional, Observational Study J. Pain Res. (IF 2.7) Pub Date : 2024-02-12 Chenhui Wang, Lei Han, Yuru Li, Xibin Mi, Mengwei Yan, Xinxiu Yu, Yu Lu, Meihong Shi, Pengfei Liu, Liang Han, Baoguo Wang
Purpose: To identify the prevalence of exacerbation of pre-existing chronic pain after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and investigate the impact of exacerbated previous chronic pain on quality of life, sleep quality, anxiety and depression levels and risk factors associated with exacerbated chronic pain among elderly coronavirus disease of 2019 (COVID-19) survivors
-
Assessment of the Effects of Sphingosine Kinase 1/Sphingosine-1-Phosphate on Microangiogenesis at Rat Myofascial Trigger Points Using Contrast-Enhanced Ultrasonography J. Pain Res. (IF 2.7) Pub Date : 2024-02-12 Xin Fang, Yalong Yin, Haimei Lun, Yaoli Liu, Shangyong Zhu
Purpose: Few studies have assessed the effects of sphingosine kinase 1/sphingosine-1-phosphate (SPHK1/S1P) on microangiogenesis at rat myofascial trigger points (MTrPs) using contrast-enhanced ultrasonography (CEUS). This study aimed to address these deficiencies. Here, we investigated the effects of SPHK1/S1P on MTrP microangiogenesis and the value of CEUS in evaluating these effects. Methods: Forty
-
Evidence-Based Opinions from Multidisciplinary Experts on Use of Naturopathic Herbal Remedies in Pain Management J. Pain Res. (IF 2.7) Pub Date : 2024-02-08 Ali Mobasheri, Aliyyaa Spring-Charles, Francesco Carlo Gamaleri, Joyce McSwan, Manohar Garg, Vidhu Sood Sethi
Background: Pharmacological approaches to acute and chronic pain management, including non-steroidal anti-inflammatory drugs (NSAIDs) and opioids, are respectively associated with adverse reactions (such as gastrointestinal, cardiovascular, and renal effects) that might limit their use in patients with comorbidities and controversy related to inappropriate use. Naturopathic remedies might offer patients
-
Optimizing Temporal Summation of Heat Pain Using a Constant Contact Heat Stimulator J. Pain Res. (IF 2.7) Pub Date : 2024-02-08 Parker A Kell, Claudia N Vore, Burkhart J Hahn, Michael F Payne, Jamie L Rhudy
Purpose: Temporal summation (TS) of pain occurs when pain increases over repeated presentations of identical noxious stimuli. TS paradigms can model central sensitization, a state of hyperexcitability in nociceptive pathways that promotes chronic pain onset and maintenance. Many experimenters use painful heat stimuli to measure TS (TS-heat); yet, TS-heat research faces unresolved challenges, including
-
Delayed-Onset Muscle Soreness Alters Mechanical Sensitivity, but Not Thermal Sensitivity or Pain Modulatory Function J. Pain Res. (IF 2.7) Pub Date : 2024-02-08 Jessica Peterson, Grant Chesbro, Michael G Bemben, Rebecca D Larson, Hugo M Pereira, Christopher D Black
Introduction: Many clinical musculoskeletal pain conditions are characterized by chronic inflammation that sensitizes nociceptors. An unresolved issue is whether inflammation affects all nociceptors in a similar manner. Exercise-induced muscle damage (EIMD) has been proposed as a model for simulating clinical inflammatory pain in healthy samples. We sought to test the effect of EIMD on various painful
-
Bibliometric Analysis of Research on Traditional Chinese Exercise and Osteoarthritis J. Pain Res. (IF 2.7) Pub Date : 2024-02-08 Qiu Zeng, Xiaoyi Liu, Lina Li, Qin Zhang, Chengping Luo, Shu Yang, Shuqiang Wu, An Yang, Jie Li
Background: Osteoarthritis (OA) is a common disease in geriatric rehabilitation medicine caused by the progressive destruction of articular cartilage. Traditional Chinese exercise (TCE) is an important component of traditional sports in China and aims to stretch the musculoskeletal tract and relieve joint pain. Bibliometrics can help researchers find suitable partners and understand the research hotspots
-
Efficacy of Lateral View Needle Placement for Sacroiliac Joint Injections J. Pain Res. (IF 2.7) Pub Date : 2024-02-07 Phillip Mitchell Johansen, Alan M Nguyen, Ali Ahmed Mohamed, Natasha Mehta, Julie Georgia Pilitsis, Benjamin Westerhaus, Anthony Giuffrida
Introduction: Sacroiliac joint (SIJ) pathology is typically diagnosed and treated with fluoroscopy-guided intraarticular injections. Most practitioners use only an anteroposterior (AP) or oblique view. Although injection into the periarticular space may yield adequate pain relief, intraarticular needle placement is imperative to identify SIJ pathology and plan future management. This study highlights
-
Development and Evaluation of a Virtual Reality Simulator for Spinal Cord Stimulation: A Randomized Controlled Trial J. Pain Res. (IF 2.7) Pub Date : 2024-02-07 Ji Yeong Kim, Yookyung Jang, Eun Jang Yoon, Wootaek Lee, Jaewoo Kim, Jae Chul Koh
Purpose: The aim of this prospective study was to develop a virtual reality simulator (VRS) for spinal cord stimulation (SCS) trials and establish its effectiveness. Methods: We developed a VRS for SCS training by integrating patient imaging data analytics, creating artificial X-ray images, and using spatial alignment techniques and virtual reality technologies. The simulator was created by a physician
-
Efficacy and Safety of Loxoprofen Sodium Hydrogel Patch in Patients with Chronic Inflammatory Pain: A 4-Week Real-World Study J. Pain Res. (IF 2.7) Pub Date : 2024-02-05 Yang Chen, Xiaoen Bian, Junnan Wang, Fang Yan, Jing Gao, Tao Sun
Purpose: Chronic inflammatory pain is usually treated with oral non-steroidal anti-inflammatory drugs (NSAIDs). However, oral NSAIDs can cause some adverse events, and local preparation is an important alternative drug. Currently, small sample clinical studies show that loxoprofen sodium hydrogel patch (LX-P) has good analgesic and anti-inflammatory effects; however, there is a lack of real-world clinical
-
Exploring Referral and Service Utilization Patterns Within an Outpatient Interdisciplinary Pediatric Chronic Pain Program J. Pain Res. (IF 2.7) Pub Date : 2024-02-03 Aimee K Hildenbrand, Christina M Amaro, Benjamin Bear, Catherine M Soprano, Katherine S Salamon
Purpose: We examine referral sources and clinical characteristics for youth presenting to an outpatient interdisciplinary pediatric chronic pain program. Patients and Methods: Referral data were extracted from the electronic health record. PROMIS Pediatric Anxiety and Pain Interference Scales were administered at an initial evaluation visit. Results: The program received 1488 referrals between 2016
-
The Short-Term Outcome of Transforaminal Epidural Steroid Injection in Patients with Radicular Pain Due to Foraminal Stenosis from Lumbar Isthmic Spondylolisthesis J. Pain Res. (IF 2.7) Pub Date : 2024-02-03 Gyu-Sik Choi, Mathieu Boudier-Revéret, Min Cheol Chang
Purpose: In this study, we evaluated the therapeutic outcomes of transforaminal epidural steroid injection (TFESI) in managing chronic radicular pain due to foraminal stenosis. Furthermore, we evaluated its effectiveness according to isthmic spondylolisthesis (IS) severity. Patients and Methods: We included 40 patients with radicular pain due to IS-derived foraminal stenosis in our study and treated
-
Artificial Intelligence and Pain Medicine: An Introduction J. Pain Res. (IF 2.7) Pub Date : 2024-02-02 Jonathan M Hagedorn, Tony K George, Rohit Aiyer, Keith Schmidt, John Halamka, Ryan S D'Souza
Abstract: Artificial intelligence was introduced 60 years ago and has evolved immensely since that time. While artificial intelligence is found in nearly all aspects of our life, the use of artificial intelligence in the healthcare industry has only recently become apparent and more widely discussed. It is expected that artificial intelligence will allow improved disease recognition, treatment optimization
-
Measurement of the Association of Pain with Clinical Characteristics in Oral Cancer Patients at Diagnosis and Prior to Cancer Treatment J. Pain Res. (IF 2.7) Pub Date : 2024-02-02 Caroline M Sawicki, Malvin N Janal, Sung Hye Gonzalez, Angie K Wu, Brian L Schmidt, Donna G Albertson
Aim: Oral cancer patients suffer pain at the site of the cancer, which degrades quality of life (QoL). The University of California San Francisco Oral Cancer Pain Questionnaire (UCSFOCPQ), the only validated instrument specifically designed for measuring oral cancer pain, measures the intensity and nature of pain and the level of functional restriction due to pain. Purpose: The aim of this study was
-
Opioid Receptor Mu 1 Gene (OPRM1) A118G Polymorphism and Emotional Modulation of Pain J. Pain Res. (IF 2.7) Pub Date : 2024-02-01 Edward A Trimble, Parker A Kell, Matteo A Avella, Christopher R France, Jamie L Rhudy
Purpose: The A118G polymorphism in the opioid receptor mu 1 gene (OPRM1) is associated with decreased opioid receptor availability, altered emotion, and increased pain. Given that emotions modulate pain (positive emotions inhibit pain, negative emotions enhance pain), we predicted that G allele carriers would experience impaired emotional modulation of pain compared to non-G allele carriers. Patients
-
Cortical Sulcal Abnormalities Revealed by Sulcal Morphometry in Patients with Chronic and Episodic Migraine J. Pain Res. (IF 2.7) Pub Date : 2024-02-01 Shanyu Liu, Xiaolin Hou, Min Shi, Yuling Shen, Zhaoying Li, Zhenzhu Hu, Dongdong Yang
Purpose: Previous studies have reported mixed results regarding the importance of cortical abnormalities in patients with migraines. However, cortical sulci, as a component of the cerebral cortex, have not been specifically investigated in migraine patients. Therefore, we aim to evaluate alterations in cortical sulcal morphology among patients with chronic migraine (CM), episodic migraine (EM), and