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Formulation development of a stable influenza recombinant neuraminidase vaccine candidate Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-18 Bing Li, Irina V. Ustyugova, Lisa Szymkowicz, Shaolong Zhu, Marin Ming, Karen Y. Y. Fung, Guadalupe Cortés, D. Andrew James, Michael Hrynyk, Nausheen Rahman, Roger H. Brookes, Salvador F. Ausar
Current influenza vaccines could be augmented by including recombinant neuraminidase (rNA) protein antigen to broaden protective immunity and improve efficacy. Toward this goal, we investigated for...
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A phase 3, single-arm, open-label study to evaluate the safety, tolerability, and immunogenicity of a 15-valent pneumococcal conjugate vaccine, V114, in a 3+1 regimen in healthy infants in South Korea (PNEU-PED-KOR) Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-18 Alvino Maestri, Su Eun Park, Fiona Fernandes, Zhongyi “Lucy” Li, Yae-Jean Kim, Yun-Kyung Kim, Jin Lee, Ji Young Park, Dong Hyun Kim, GyongSeon Yang, Hyunjung Lim, Jin Oh Kim, Robert Lupinacci, Tina M. Sterling, Marissa Wilck, Alejandra Esteves-Jaramillo, Natalie Banniettis
There is an ongoing burden of pneumococcal disease in children despite the use of pneumococcal conjugate vaccines (PCVs). This phase 3, open-label, single-arm, multisite, descriptive study was desi...
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Mapping the intellectual structure and landscape of colorectal cancer immunotherapy: A bibliometric analysis Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-18 Qin Ling Ou, Yong Long Chang, Jin Hui Liu, Hai Xia Yan, Lin Zi Chen, Duan Yang Guo, Si Fang Zhang
Immunotherapy, particularly immune checkpoint inhibitor (ICIs) therapy, stands as an innovative therapeutic approach currently garnering substantial attention in cancer treatment. It has become a f...
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Community based participatory research as a promising practice for addressing vaccine hesitancy, rebuilding trust and addressing health disparities among racial and ethnic minority communities Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-18 Sophie E. O’Bryan, Fatima Muñoz, David Smith, Adriana Bearse, Blanca Melendrez, Biren Kamdar, Cynthia James-Price, Daniel Ramirez, Argentina E. Servin
The COVID-19 pandemic disproportionately affected racial and ethnic minority communities across the United States (U.S.). Despite the disproportionate burden of COVID-19 faced by communities of col...
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Real-life experience on COVID-19 and seasonal influenza vaccines co-administration in the vaccination hub of the University Hospital of Palermo, Italy Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-18 Claudio Costantino, Walter Mazzucco, Arianna Conforto, Livia Cimino, Alessia Pieri, Sara Rusignolo, Nicole Bonaccorso, Floriana Bravatà, Laura Pipitone, Martina Sciortino, Marcello Tocco, Elena Zarcone, Giorgio Graziano, Fabio Tramuto, Carmelo Massimo Maida, Alessandra Casuccio, Francesco Vitale
With the pandemic, there has been a global reduction in influenza virus circulation, with WHO reporting, during 2021/22 season, laboratory testing positivity rate for influenza of less than 3%. Inf...
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Changes in vaccine coverage and incidence of acute gastroenteritis and severe rotavirus gastroenteritis in children <5 years in Shibata City, Niigata Prefecture, Japan Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-13 Tomohiro Oishi, Satoshi Hasegawa, Tokushi Nakano, Shoji Sudo, Hiroaki Kuwajima, Shuko Tokuriki, Tsutomu Tamura
Rotavirus (RV) vaccines were first introduced in 2011 and adopted for universal vaccination in 2020 in Japan. However, the effectiveness of RV vaccines after being adopted for universal vaccination...
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Editorial to special issue “The power of immunoprofiling supported by computational data integration and machine learning” Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-15 Elke Bergmann-Leitner
Published in Human Vaccines & Immunotherapeutics (Vol. 20, No. 1, 2024)
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Unraveling the copper-death connection: Decoding COVID-19‘s immune landscape through advanced bioinformatics and machine learning approaches Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-11 Qi Wang, Zhenzhong Su, Jing Zhang, He Yan, Jie Zhang
This study aims to analyze Coronavirus Disease 2019 (COVID-19)-associated copper-death genes using the Gene Expression Omnibus (GEO) dataset and machine learning, exploring their immune microenviro...
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Real-world effectiveness of recombinant zoster vaccine in self-identified Chinese individuals aged ≥50 years in the United States Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-15 Ana Florea, Lina Sy, Lei Qian, Bradley Ackerson, Yi Luo, Jun Wu, Yanjun Cheng, Jennifer Ku, Leticia Vega Daily, Harpreet Takhar, Jeannie Song, Elizabeth Chmielewski-Yee, O’Mareen Spence, Harry Seifert, Driss Oraichi, Hung Fu Tseng
We evaluated the vaccine effectiveness (VE) of two doses of recombinant zoster vaccine (RZV) against herpes zoster (HZ) and postherpetic neuralgia (PHN) in Chinese adults at Kaiser Permanente South...
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Using big data to analyze the vaccination status of children with congenital heart disease in Yinzhou District, China Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-11 Lin Zhang, Ziliang Yang, Yueqi Yin, Wenzan Huang, Tianfei Yi, Jianming Ping, Liya Liu, Peng Shen, Yexiang Sun, Hongbo Lin
Congenital heart disease (CHD) represents a significant population warranting particular attention concerning vaccination coverage. To comprehend the vaccination status of CHD within Yinzhou Distri...
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Human vaccines and immunotherapeutics: News February 2024 Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-13 Ronald Ellis, Adam Weiss
Published in Human Vaccines & Immunotherapeutics (Vol. 20, No. 1, 2024)
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Protective doses of tetanus toxoid immunization and its associated factors among mothers in southern Ethiopia Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-11 Maycas Gembe, Teklu Wosenyeleh, Wubishet Gezimu
The World Health Organization recommends tetanus toxoid immunization before or during pregnancy for all women of childbearing age. The goal is to reduce maternal and neonatal mortality due to tetan...
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Seroprevalence of tetanus and pertussis antibodies among health care workers in Wuhu, China Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-11 Wei Shi, Bingsong Wang, Qinghong Meng, Xianlai Zhang, Zhen Li, Fang He, Fei Ying, Linyan Cong, Kaihu Yao
This study aimed to elucidate the seroprevalence of antibodies to tetanus and pertussis among Chinese health care workers. Blood specimens from health care workers were collected during the 2021 an...
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Immunogenicity of COVID-19 vaccines in patients with cirrhosis: A meta-analysis Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-11 Lichen Ouyang, Gang Lei, Yeli Gong
The immunogenicity of COVID-19 vaccines in patients with liver cirrhosis remains largely unknown. The purpose of this meta-analysis was to investigate the immunogenicity of COVID-19 vaccines in pat...
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Using an extended information-motivation-behavioral skills model to explain HPV vaccination intention among men who have sex with men only and men who have sex with men and women Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-11 Guiqian Shi, Bing Lin, Haiying Pan, Wei He, Xiaoni Zhong
Men who have sex with men and women (MSMW) have been reported to differ in psychosocial and sexual behavior patterns from men who have sex with men only (MSMO). However, results regarding the diffe...
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An analysis of reported cases shoulder injury related to vaccine administration of after COVID-19 vaccination Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-04 Zixin Li, Shijie Chen, Mingyi Zhao
To prevent COVID-19, the COVID-19 vaccine has been widely administered worldwide, but various complications accompany this vaccine. The aim of this study was to investigate the demographic patterns...
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COVID-19 vaccine hesitancy among the Chinese elderly: A multi-stakeholder qualitative study Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-04 Xiaoyu Li, Yanping Bai, Lijun Weng, Yunshan Bai, Wenjie Gong
The United Nations reported that the mortality risk of Corona Virus Disease 2019 (COVID-19) is five times higher in the elderly than the global average. Although the COVID-19 vaccine effectively pr...
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Knowledge, attitude, and practice toward herpes zoster (HZ) and HZ vaccination: Concept elicitation findings from a multi-country study in the Asia Pacific Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-04 Jing Chen, Sumitra Shantakumar, Jennifer Si, Regina Gowindah, Raunak Parikh, Felix Chan, Macy Chan, Won Suk Choi, Erick Huang, Kuo-Chin Huang, Li-Min Huang, Hyungwoo Kim, Choon Kit Leong, Hoe-Nam Leong, Yubin Seo, Charles Williams, Andrew TY Wong
Herpes zoster (HZ) is a prevalent disease characterized by a painful rash. A multi‑country study was conducted to elicit public and physician knowledge, attitude, and practice (KAP) toward HZ disea...
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The role of vaccine literacy and health literacy in the health prevention decision-making process Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-06 Claudia Isonne, Carolina Marzuillo, Paolo Villari, Valentina Baccolini
Published in Human Vaccines & Immunotherapeutics (Vol. 20, No. 1, 2024)
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Factors influencing adverse events following COVID-19 vaccination Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-06 Paola Villanueva, Ellie McDonald, Julio Croda, Mariana Garcia Croda, Margareth Dalcolmo, Glauce dos Santos, Bruno Jardim, Marcus Lacerda, David J. Lynn, Helen Marshall, Roberto D. Oliveira, Jorge Rocha, Alice Sawka, Fernando Val, Laure F. Pittet, Nicole L. Messina, Nigel Curtis
Various novel platform technologies have been used for the development of COVID-19 vaccines. In this nested cohort study among healthcare workers in Australia and Brazil who received three differen...
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Enhanced passive safety surveillance of high-dose and standard-dose quadrivalent inactivated split-virion influenza vaccines in Germany and Finland during the 2022/23 influenza season Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-06 Marina Amaral de Avila Machado, Sonja Gandhi-Banga, Sophie Gallo, Tathyana Giannotti Cousseau, Reddappa Maniganahally Byrareddy, Markku Nissilä, Jörg Schelling, Celine Monfredo
Enhanced Passive Safety Surveillance (EPSS) was conducted for quadrivalent inactivated split-virion influenza vaccines (IIV4) in Germany (high dose [HD]) and Finland (standard dose [SD]) for the no...
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Parental intention on getting children COVID-19 vaccinations: Invariance evaluation across parenting roles and COVID-19-like symptoms experiences among Iranians during the pandemic period Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-06 Daniel Kwasi Ahorsu, Marc N. Potenza, Chung-Ying Lin, Amir H. Pakpour
Countries worldwide are facing challenges with increasing the COVID-19 vaccination rates for children. This study examined associations between perceived knowledge, coping appraisal, threat apprais...
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Introduction of the pneumococcal conjugate vaccine in humanitarian and fragile contexts: Perspectives from stakeholders in four African countries Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-05 Baldeep K. Dhaliwal, Rose Weeks, Jasmine Huber, Aminata Fofana, Mohamed Bobe, Antoinette Demian Mbailamen, George Legge, Gassim Cisse, Anita Shet
Childhood pneumonia causes a significant burden of preventable child morbidity and mortality in Chad, Guinea, Somalia/Somaliland, and South Sudan. Leaders from these countries have committed to red...
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Enhancing vaccine effectiveness in the elderly to counter antibiotic resistance: The potential of adjuvants via pattern recognition receptors Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-04 Myunghwan Jung, Hongmin Kim, Eunsol Choi, Min-Kyoung Shin, Sung Jae Shin
Vaccines are an effective way to prevent the emergence and spread of antibiotic resistance by preventing diseases and establishing herd immunity. However, the reduced effectiveness of vaccines in t...
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Attitudes toward a future norovirus vaccine among members of an integrated healthcare delivery system in Portland, Oregon, 2016-2017 Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-28 Holly C. Groom, Mark Schmidt, Laura E. Calderwood, Sara A. Mirza, Claire Mattison, Suzanne Salas, Judy Donald, Allison L. Naleway
With recent advances in U.S. clinical trials for norovirus vaccines, it is an opportune time to examine what is known about the public receptivity to this novel vaccine. From October 2016–September...
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Awareness, knowledge, disease prevention practices, and immunization attitude of hepatitis E virus among food handlers in Klang Valley, Malaysia Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-03-03 Sakshaleni Rajendiran, Wong Li Ping, Yuvaneswary Veloo, Syahidiah Syed Abu Thahir
Concern about the zoonotic Hepatitis E virus (HEV) is rising. Since, food handlers are at greater risk in contracting HEV, the present study aims to determine awareness, knowledge, prevention pract...
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Immune regulation and the tumor microenvironment in anti-PD-1/PDL-1 and anti-CTLA-4 therapies for cancer immune evasion: A bibliometric analysis Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-28 Yi Huang, Zhijian Chen, Gang Shen, Shuogui Fang, Junjiong Zheng, Zepai Chi, Yuanfeng Zhang, Yitong Zou, Qinghua Gan, Chengxiao Liao, Yuhui Yao, Jianqiu Kong, Xinxiang Fan
This study aims to conduct a bibliometric analysis, employing visualization tools to examine literature pertaining to tumor immune evasion related to anti-CTLA-4 and anti-PD-1/PD-L1 therapy from 19...
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Prevention of bleomycin-induced pulmonary fibrosis by vaccination with the Tocilizumab mimotope Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-26 Jin Guo, Lin Yang, Haoming Song, Li Bai
Mimotope, a kind of peptide vaccine, is developed to bind natural receptor and inhibit the downstream signaling. We have demonstrated that the vaccination of Tocilizumab mimotopes could alleviate t...
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Politics and confidence toward the COVID-19 vaccination: A Brazilian cross-sectional study Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-26 Marco Antonio Catussi Paschoalotto, Joana Cima, Eduardo Costa, Sara Valente de Almeida, Joana Gomes da Costa, João Vasco Santos, Claudia Souza Passador, João Luiz Passador, Pedro Pita Barros
This study has the aim of assessing the Brazilian perceptions, influencing factors and political positioning on the confidence concerning COVID-19 vaccination. To achieve the objective, the methods...
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A systematic literature review of human papillomavirus vaccination strategies in delivery systems within national and regional immunization programs Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-27 Marisa Felsher, Meheret Shumet, Cristinela Velicu, Ya-Ting Chen, Kinga Nowicka, Magdalena Marzec, Gabriela Skowronek, Izabela Pieniążek
The uptake of human papillomavirus (HPV) vaccine remains suboptimal despite being a part of routine vaccination within national immunization program(s). This indicates probable challenges with the ...
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First pediatric B-acute lymphoblastic leukemia patient treated with anti-CD19 chimeric antigen receptor T-cell therapy: Long-term remission or early cure? Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-25 Dimitrios Bouzianas, Stella Bouziana
Published in Human Vaccines & Immunotherapeutics (Vol. 20, No. 1, 2024)
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Sustainable financing for vaccination towards advancing universal health coverage in the WHO African region: The strategic role of national health insurance Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-27 Abdu A. Adamu, Rabiu I. Jalo, Ibrahim D. Muhammad, Téné-Alima Essoh, Duduzile Ndwandwe, Charles S. Wiysonge
There is a growing political interest in health reforms in Africa, and many countries are choosing national health insurance as their main financing mechanism for universal health coverage. Althoug...
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Safety and reactogenicity of the BNT162b2 COVID-19 vaccine: Development, post-marketing surveillance, and real-world data Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-26 Frank van den Ouweland, Nicola Charpentier, Özlem Türeci, Ruben Rizzi, Federico J. Mensa, Claudia Lindemann, Shanti Pather
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to urgent actions by innovators, vaccine developers, regulators, and other stakeholders to ensure public acce...
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Parental willingness of HPV vaccination in Mainland China: A meta-analysis Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-22 Sensen Tan, Sumeng Wang, Xunwen Zou, Xinhua Jia, Chenyunhao Tong, Jian Yin, Xuemei Lian, Youlin Qiao
This meta-analysis aimed to systematically review and analyze parental awareness of human papillomavirus (HPV) and its vaccine, as well as parental willingness of the HPV vaccine in China. The lite...
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The evolution of vaccine hesitancy through the COVID-19 pandemic: A semi-structured interview study on booster and bivalent doses Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-23 Jeanna Parsons Leigh, Emily A. FitzGerald, Stephana Julia Moss, Michal S. Cherak, Rebecca Brundin-Mather, Alexandra Dodds, Henry T. Stelfox, Ève Dubé, Kirsten M. Fiest, Donna M. Halperin, Sofia B. Ahmed, Shannon E. MacDonald, Sharon E. Straus, Terra Manca, Josh Ng Kamstra, Andrea Soo, Shelly Longmore, Shelly Kupsch, Bonnie Sept, Scott A. Halperin
We sought in-depth understanding on the evolution of factors influencing COVID-19 booster dose and bivalent vaccine hesitancy in a longitudinal semi-structured interview-based qualitative study. Se...
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A scoping review of active, participant centred, digital adverse events following immunization (AEFI) surveillance of WHO approved COVID-19 vaccines: A Canadian immunization Research Network study Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-19 Mohamed Serhan, Athanasios Psihogios, Nooh Kabir, A. Brianne Bota, Salima S. Mithani, David P. Smith, David T. Zhu, Devon Greyson, Sarah Wilson, Deshayne Fell, Karina A. Top, Julie A. Bettinger, Kumanan Wilson
This scoping review examines the role of digital solutions in active, participant-centered surveillance of adverse events following initial release of COVID-19 vaccines. The goals of this paper wer...
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Real-world data of China: Analysis of HPV vaccine coverage and post-vaccination adverse reaction monitoring in Western Chinese provinces from 2018 to 2021 Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-19 Jing An, Yan Liu, Yingchun Ma, Yong-Zhuo Jiao, Xue-Feng Liang, Na Jin, Junyi Bao, Nan Jiang, Xiao-Shu Zhang
To investigate the HPV vaccine coverage and post-vaccination adverse reactions in Gansu Province, Western China, from 2018 to 2021. Data on suspected adverse reactions to HPV vaccines were collecte...
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High impact of quadrivalent human papillomavirus vaccine across racial/ethnic groups: National Health and Nutrition Examination Survey, 2003–2006 and 2015–2018 Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-19 Ruth Stefanos, Rayleen M. Lewis, Troy D. Querec, Julia W. Gargano, Elizabeth R. Unger, Lauri E. Markowitz
Human papillomavirus (HPV) causes cervical as well as other cancers. Racial and ethnic disparities in cervical cancer incidence and mortality in the United States are well documented. HPV vaccinati...
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Perceptions about respiratory syncytial virus (RSV) and attitudes toward the RSV vaccine among the general public in China: A cross-sectional survey Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-18 Qiang Wang, Shixin Xiu, Liuqing Yang, Lan Li, Min Yang, Xuwen Wang, Yuan Shen, Weibing Wang, Leesa Lin
Our study aims to assess the public’s perceptions of respiratory syncytial virus (RSV) and attitudes toward the RSV vaccine and to identify associated factors in China. A nationwide cross-sectional...
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Development of a quantitative ELISA for SARS-CoV-2 vaccine candidate, NDV-HXP-S, with CpG 1018® adjuvant Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-19 Marcus Estrada, Changcheng Zhu, Anan Bzami, Jessica A. White, Manjari Lal
NDV-HXP-S is a Newcastle disease virus (NDV) vectored vaccine candidate which expresses the S-antigen of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This vaccine candidate is unde...
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Perceived impact of discussions with a healthcare professional on patients’ decision regarding COVID-19 vaccine Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-12 Alric Charmasson, Marie Ecollan, Philippe Jaury, Henri Partouche, Adèle Frachon, Juliette Pinot
There is evidence that advice from Healthcare Professionals (HCPs) plays an important role in patients’ decision to get vaccinated, but the extent to which patients perceive this impact is unclear....
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Reconsidering the inclusion of Ladapo’s work in the meta-analysis: Validity concerns and implications Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-15 Borja Somovilla Del Saz
This is a response to Marchand & Masoud’s response letter regarding my criticism “Response to Dr. Somovilla del Saz’s letter to the editor regarding “Risk of all-cause and cardiac-related mortality...
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Serological assessment of the durability of vaccine-mediated protection against SARS-CoV-2 infection Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-15 John T. Bates, Seth T. Lirette, Andrew P. Farmer, Michael A. Bierdeman, Kristina B. Seyfarth, Dallas R. Ederer, Denise D. Montgomery, Grace C. Burnett, Amanda T. Pham, Gailen D. Marshall
Virus-neutralizing antibodies are often accepted as a correlate of protection against infection, though questions remain about which components of the immune response protect against SARS-CoV-2 inf...
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Cost-based COVID-19 vaccination and willingness to pay: A post-pandemic review Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-15 Li Ping Wong, Hai Yen Lee, Haridah Alias, Gregory Zimet, Tongyu Liu, Yulan Lin, Zhijian Hu
The primary objective of this paper is to serve as a valuable resource for policymakers who are confronted with the evolving landscape of the coronavirus disease 2019 (COVID-19), considering both f...
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Impact of the COVID-19 pandemic on social media utilization, influences related to parental vaccine decision making, and opinions on trustworthy social media vaccination campaigns: A qualitative analysis Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-14 Holly B. Fontenot, Kevin M. Quist, Gary Glauberman, Alexandra Michel, Gregory Zimet
There is a continued need for research to better understand the influence social media has on parental vaccination attitudes and behaviors, especially research capturing the effects of the COVID-19...
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The trends and hotspots of immunotherapy for metastatic colorectal cancer from 2013 to 2022: A bibliometric and visual analysis Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-14 Yifan Gong, Jianping Kang, Mingting Wang, Firdaus Hayati, Syed Sharizman Syed Abdul Rahim, Lucky Poh Wah Goh
An increasing body of research indicates that immunotherapy has demonstrated substantial effectiveness in the realm of metastatic colorectal cancer(mCRC), especially among patients with deficient m...
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Ethical concerns regarding heterologous COVID-19 vaccine administration Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-14 Somsri Wiwanitkit, Viroj Wiwanitkit
Published in Human Vaccines & Immunotherapeutics (Vol. 20, No. 1, 2024)
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Exploration of genetic characterization in hyperprogressive disease after immunotherapy retreatment in a patient with LCNEC: A case report Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-13 Yao Zhang, Jiayao Yang, Tianyu Shao, Jialu Chen, Qijin Shu, Liumei Shou
Immune checkpoint inhibitors (ICIs) have emerged as a promising therapeutic option for large cell neuroendocrine carcinoma (LCNEC). However, various studies have suggested a potential risk of hyper...
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The community nurse’s role on the promotion of papillomavirus vaccination among young students: A study protocol Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-14 Valentina Simonetti, Marco Tomietto, Dania Comparcini, Francesco Pastore, Pasquale Stefanizzi, Silvio Tafuri, Giancarlo Cicolini
Vaccination is the principal strategy for primary prevention of infection by Human Papilloma Virus (HPV), which causes different pathological conditions, up to cancer, in both males and females. Ho...
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Neutralizing antibody titers over 12 months after SARS-CoV-2 mRNA vaccine booster in patients with relapsing multiple sclerosis continuously treated with ofatumumab Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-12 Tjalf Ziemssen, Marie Groth, Benjamin Ettle, Tobias Bopp
Booster vaccinations against SARS-CoV-2 are recommended 6–12 months after the last dose or infection in elderly and high-risk groups. The present analysis aims to evaluate whether an interval short...
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“Going vaccine hunting”: Multilevel influences on COVID-19 vaccination among racialized sexual and gender minority adults—a qualitative study Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-12 Peter A. Newman, Duy Anh Dinh, Notisha Massaquoi, Charmaine C. Williams, Ashley Lacombe-Duncan, Suchon Tepjan, Thabani Nyoni
High levels of COVID-19 vaccine hesitancy have been reported among Black and Latinx populations, with lower vaccination coverage among racialized versus White sexual and gender minorities. We exami...
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Relevance of mutation-derived neoantigens and non-classical antigens for anticancer therapies Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-12 Belen Aparicio, Patrick Theunissen, Sandra Hervas-Stubbs, Puri Fortes, Pablo Sarobe
Efficacy of cancer immunotherapies relies on correct recognition of tumor antigens by lymphocytes, eliciting thus functional responses capable of eliminating tumor cells. Therefore, important effor...
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Change in intention and hesitancy regarding COVID-19 vaccines in a cohort of adults in Quebec during the pandemic Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-12 Maude Dionne, Louis Rochette, Denis Hamel, Ève Dube
Although COVID-19 vaccine uptake was high in Quebec for the primary series, vaccine acceptance decreased for the subsequent booster doses. This article presents the evolution of vaccine intention, ...
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A phase 4, open-label study to evaluate the safety and immunogenicity of DTaP5-HBV-IPV-Hib in children previously vaccinated with DTaP2-HBV-IPV-Hib or DTaP5-HBV-IPV-Hib (V419-016) Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-08 Andrea Guerra, Claudio Costantino, Federico Martinon-Torres, Soeren Westerholt, Courtney Lambeth, Ziqiang Chen, Jessie Lumley, Tomas Marcek, David Johnson, Marissa Wilck
DTaP5-HBV-IPV-Hib (Vaxelis®) is a hexavalent combination vaccine (HV) indicated in infants and toddlers for the prevention of diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis, and invasiv...
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Another measles outbreak in the Philippines? The essentiality of a successful vaccination program and public cooperation Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-12 Dalmacito A. Cordero Jr.
Published in Human Vaccines & Immunotherapeutics (Vol. 20, No. 1, 2024)
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Cost-effectiveness analysis of vaccination strategies against meningococcal disease for children under nine years of age in China Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-13 Haonan Zhang, Haijun Zhang, Hai Fang
Meningococcal vaccination strategies in China are intricate, including multiple vaccines targeting different serogroups. The current National Immunization Program (NIP) includes two polysaccharide ...
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Vaccines targeting ESR1 activating mutations elicit anti-tumor immune responses and suppress estrogen signaling in therapy resistant ER+ breast cancer Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-08 Gabrielle P. Dailey, Christopher A. Rabiola, Gangjun Lei, Junping Wei, Xiao-Yi Yang, Tao Wang, Cong-Xiao Liu, Melissa Gajda, Amy C. Hobeika, Amanda Summers, Robert D. Marek, Michael A. Morse, Herbert K. Lyerly, Erika J. Crosby, Zachary C. Hartman
ER+ breast cancers (BC) are characterized by the elevated expression and signaling of estrogen receptor alpha (ESR1), which renders them sensitive to anti-endocrine therapy. While these therapies a...
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Bibliometric analysis of immunotherapy for bladder cancer: A correspondence Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-08 Ruochen Bao, Hongtao Qu, Baifeng Li, Kai Cheng, Yandong Miao, Jiangtao Wang
Published in Human Vaccines & Immunotherapeutics (Vol. 20, No. 1, 2024)
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“Why has this new vaccine come and for what reasons?” key antecedents and questions for acceptance of a future maternal GBS vaccine: Perspectives of pregnant women, lactating women, and community members in Kenya Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-12 Rupali J. Limaye, Prachi Singh, Berhaun Fesshaye, Clarice Lee, Jessica Schue, Ruth A. Karron
Group B streptococcus (GBS) is a leading global cause of neonatal sepsis and meningitis, stillbirth, and puerperal sepsis. While intrapartum antibiotic prophylaxis (IAP) is a currently available GB...
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Human vaccines and immunotherapeutics: News January 2024 Hum. Vaccines Immunother. (IF 4.8) Pub Date : 2024-02-07 Ronald Ellis, Adam Weiss
Published in Human Vaccines & Immunotherapeutics (Vol. 20, No. 1, 2024)