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Assessment of Antioxidant Enzyme Superoxide Dismutase (SOD) in Oral Cancer: Systematic Review and Meta-Analysis Dis. Markers (IF 3.464) Pub Date : 2024-3-16 Khadijah Mohideen, Krithika Chandrasekaran, Kareema M, Jeyanthikumari T, Safal Dhungel, Snehashish Ghosh
Objective. The present article aims to comprehensively review the existing literature on superoxide dismutase (SOD) levels, an antioxidant enzyme, in oral cancer. Method. An extensive literature search was conducted across various databases, including PubMed, Wiley Online Library, Science Direct, and Cross Reference, spanning 1998–2023. At the outset, 1,177 articles were initially identified, and 907
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Circulating Nucleic Acids in Colorectal Cancer: Diagnostic and Prognostic Value Dis. Markers (IF 3.464) Pub Date : 2024-2-13 Somayeh Igder, Mozhdeh Zamani, Shima Fakher, Morvarid Siri, Hassan Ashktorab, Negar Azarpira, Pooneh Mokarram
Colorectal cancer (CRC) is the third most prevalent cancer in the world and the fourth leading cause of cancer-related mortality. DNA (cfDNA/ctDNA) and RNA (cfRNA/ctRNA) in the blood are promising noninvasive biomarkers for molecular profiling, screening, diagnosis, treatment management, and prognosis of CRC. Technological advancements that enable precise detection of both genetic and epigenetic abnormalities
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Neutrophil–Lymphocyte and Platelet–Lymphocyte Ratios in Distinguishing Lung Cancer in People with HIV Dis. Markers (IF 3.464) Pub Date : 2024-1-23 Joseph Baruch Baluku, Sharon Namiiro, Brenda Namanda, Martin Nabwana, Irene Andia-Biraro, William Worodria, Robert Salata, Sayoki Mfinanga, Stanton Gerson, Bruce Kirenga
Objective. The neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) demonstrate good diagnostic accuracy in distinguishing lung cancer patients from healthy individuals, primarily in HIV-negative populations. We determined the sensitivity (Se), specificity (Sp), and area under the curve (AUC) of the NLR and PLR in discriminating between people living with HIV (PLWH) with and without
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Examining the Association of Rare Allelic Variants in Urate Transporters SLC22A11, SLC22A13, and SLC17A1 with Hyperuricemia and Gout Dis. Markers (IF 3.464) Pub Date : 2024-1-6 Jiří Vávra, Kateřina Pavelcová, Jana Mašínová, Lenka Hasíková, Eliška Bubeníková, Aneta Urbanová, Andrea Mančíková, Blanka Stibůrková
Genetic variations in urate transporters play a significant role in determining human urate levels and have been implicated in developing hyperuricemia or gout. Polymorphism in the key urate transporters, such as ABCG2, URAT1, or GLUT9 was well-documented in the literature. Therefore in this study, our objective was to determine the frequency and effect of rare nonsynonymous allelic variants of SLC22A11
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Arterial Hypertension and Its Consequences Are the Main Predictors of Embolic Stroke of Undetermined Source Dis. Markers (IF 3.464) Pub Date : 2023-11-16 Alexander B. Berdalin, Daria D. Namestnikova, Elvira A. Cherkashova, Denis A. Golovin, Ilya L. Gubskiy, Vladimir G. Lelyuk
Background and Purpose. Embolic stroke of undetermined source (ESUS) is a subcategory of cryptogenic stroke with high frequency of occurrence and insufficient understanding its risk factors leads to the lack of determined strategies for primary/secondary prevention. This study was aimed to identify the most prominent predictors of the ESUS and to generate the overall predictive model. Methods. We performed
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Exploration of Metabolite Biomarkers to Predict the Efficacy of Dupilumab Treatment for Atopic Dermatitis Dis. Markers (IF 3.464) Pub Date : 2023-11-1 Shoko Miyamoto, Yasutomo Imai, Masako Matsutani, Makoto Nagai, Kiyofumi Yamanishi, Nobuo Kanazawa, Shin Nishiumi
Dupilumab (DUP) is the first biological agent used treating atopic dermatitis (AD). Notwithstanding its high cost, the type of patient group for which the drug is effective remains unclear. In this retrospective study, we aimed to identify novel and reliable biomarkers which can be measured before DUP administration and to predict the efficacy of DUP. Serum samples from 19 patients with AD treated
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Meta-Analysis of Assessment of Total Oxidative Stress and Total Antioxidant Capacity in Patients with Periodontitis Dis. Markers (IF 3.464) Pub Date : 2023-10-30 Khadijah Mohideen, Krithika Chandrasekaran, Harsha Veeraraghavan, Shahul Hameed Faizee, Safal Dhungel, Snehashish Ghosh
Background. Periodontitis is intricately linked to oxidative stress-antioxidant (redox) imbalance. The antioxidant system scavenges the oxygen free radicals in biological fluids in patients with periodontitis. However, little is still known about the free radicals mediated oxidative stress and reductive ability of the antioxidant system. Thus, the present meta-analysis aims to quantitatively review
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Insights into the Role of Galectin-3 as a Diagnostic and Prognostic Biomarker of Atrial Fibrillation Dis. Markers (IF 3.464) Pub Date : 2023-10-9 Yasmin Mohtasham Kia, Alessandro Cannavo, Pegah Bahiraie, Sanam Alilou, Behrad Saeedian, Nastaran Babajani, Elina Ghondaghsaz, Amirmohammad Khalaji, Amir Hossein Behnoush
Atrial fibrillation (AF) is an irregular atrial activity and the most prevalent type of arrhythmia. Although AF is easily diagnosed with an electrocardiogram, there is a keen interest in identifying an easy-to-dose biomarker that can predict the prognosis of AF and its recurrence. Galectin-3 (Gal-3) is a beta-galactoside binding protein from the lectin family with pro-fibrotic and -inflammatory effects
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Correlation Analysis of Prognostic Gene Expression, Tumor Microenvironment, and Tumor-Infiltrating Immune Cells in Ovarian Cancer Dis. Markers (IF 3.464) Pub Date : 2023-10-6 Qing Li, Zongjing Yang, Xingqing Ling, Junming Ye, Jiaying Wu, Yu Wang, Chun Yao, Jinghui Zheng
Objective. Tumor microenvironment (TME) research can provide a crucial direction for the innovation and continuous improvement of novel biologic therapies for cancer. This study examined the relationship between the TME, expression profiles of the tumor-infiltrating immune cell, and prognostic gene expression in ovarian cancer (OC). Materials and Methods. Screening of CD3E, CD3G, CD2, CD3D, CCL19,
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Retracted: Expression Profile and Prognostic Values of CDH Family Members in Lung Adenocarcinoma. Dis. Markers (IF 3.464) Pub Date : 2023-10-04 Disease Markers
[This retracts the article DOI: 10.1155/2022/9644466.].
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hsa_circ_0129047 Upregulates LYVE1 to Inhibit Hepatocellular Carcinoma Progression by Sponging miR-492 Dis. Markers (IF 3.464) Pub Date : 2023-9-30 Zhenzhen Feng, Jiyuan Wu
Compelling evidence indicates the regulatory role of circular RNAs in cancers, including hepatocellular carcinoma (HCC). Our study aimed to elucidate the regulatory function of circ_0129047 in HCC progression. A reverse transcription-quantitative polymeric chain reaction was conducted to detect the expression of circ_0129047, lymphatic vessel endothelial hyaluronan receptor-1 (LYVE1), and miR-492 in
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Retracted: Peptide ARHGEF9 Inhibits Glioma Progression via PI3K/AKT/mTOR Pathway. Dis. Markers (IF 3.464) Pub Date : 2023-08-09 Disease Markers
[This retracts the article DOI: 10.1155/2023/7146589.].
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Retracted: Identification of Atrial Fibrillation-Related lncRNA Based on Bioinformatic Analysis. Dis. Markers (IF 3.464) Pub Date : 2023-08-02 Disease Markers
[This retracts the article DOI: 10.1155/2022/8307975.].
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Retracted: Study on Circulating lncRNA Expression Profile in Patients with Cerebral Infarction. Dis. Markers (IF 3.464) Pub Date : 2023-08-02 Disease Markers
[This retracts the article DOI: 10.1155/2022/3042105.].
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Retracted: Anesthetic Effect of Dexmedetomidine in Clinical Functional Neurosurgery. Dis. Markers (IF 3.464) Pub Date : 2023-08-02 Disease Markers
[This retracts the article DOI: 10.1155/2022/6000388.].
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Retracted: Apelin Alleviates Meniscus Endothelial Cell Apoptosis in Osteoarthritis. Dis. Markers (IF 3.464) Pub Date : 2023-08-02 Disease Markers
[This retracts the article DOI: 10.1155/2022/3556372.].
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Retracted: PM2.5 Exposure Induces Lung Injury and Fibrosis by Regulating Ferroptosis via TGF-β Signaling. Dis. Markers (IF 3.464) Pub Date : 2023-07-26 Disease Markers
[This retracts the article DOI: 10.1155/2022/7098463.].
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Retracted: E2F1 Affects the Therapeutic Response to Neoadjuvant Therapy in Breast Cancer. Dis. Markers (IF 3.464) Pub Date : 2023-07-26 Disease Markers
[This retracts the article DOI: 10.1155/2022/8168517.].
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Retracted: Correlation between Intestinal Microflora in Irritable Bowel Syndrome and Severity. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/1031844.].
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Retracted: Effect of HIV-1 Protease Inhibitor on IL-18 and IL-1β in Rats with Insulinoma. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/1868749.].
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Retracted: CKS2 and S100A12: Two Novel Diagnostic Biomarkers for Rheumatoid Arthritis. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/2431976.].
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Retracted: The Higher Expression of CDCA2 Associated with Poor Prognosis in Glioma. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/2184867.].
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Retracted: Clinical Characteristics and Risk Factors for Pulmonary Infection in Emergency ICU Patients. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/7711724.].
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Retracted: lncRNA GAS5 Induces Cell Apoptosis in Acute Myeloid Leukemia by Targeting Nrf2. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/5178122.].
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Retracted: Posterior Lumbar Plexus Block Anesthesia for Elderly Patients with Lower Limb Fracture. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/8494796.].
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Retracted: PTPN11 Gene Mutations and Its Association with the Risk of Congenital Heart Disease. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/8290779.].
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Retracted: Research Progress of PI3K/PTEN/AKT Signaling Pathway Associated with Renal Cell Carcinoma. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/1195875.].
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Retracted: HSPA5 Inhibitor Meliorate DSS-Induced Colitis through HSPA1A/CHIP. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/7115181.].
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Retracted: Expression and Clinical Significance of HER2 Gene and DNMT1 in Non-Small-Cell Lung Cancer. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/8426384.].
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Retracted: Functional Analysis of Serum Long Noncoding RNAs in Patients with Atrial Fibrillation. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/2799123.].
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Retracted: DDTC Suppresses Ovarian Cancer Development via the PI3K/AKT/mTOR Signaling Pathway. Dis. Markers (IF 3.464) Pub Date : 2023-07-19 Disease Markers
[This retracts the article DOI: 10.1155/2022/1941077.].
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Evaluation of lncRNA Expression Pattern and Potential Role in Heart Failure Pathology Dis. Markers (IF 3.464) Pub Date : 2023-7-12 Xiatian Chen, Chengzhen Shi, Jinning Gao, Juan Carlos Cueva Jumbo, Yin Wang, Xin Li, Cheng Zhao, Hua Yu, Peifeng Li, Lynn Htet Htet Aung
During the last few decades, the morbidity and mortality of heart failure (HF) have remained on an upward trend. Despite the advances in therapeutic and diagnostic measures, there are still many aspects requiring further research. This study is aimed at finding potential long noncoding RNAs (lncRNAs) that could aid with the diagnosis and treatment of HF. We performed RNA sequencing on the peripheral
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Retracted: Environmental and Genetic Factors in the Pathogenesis of COPD in the Road-Working Population. Dis. Markers (IF 3.464) Pub Date : 2023-07-12 Disease Markers
[This retracts the article DOI: 10.1155/2021/9953234.].
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Retracted: Study on the Effect of MRI in the Diagnosis of Benign and Malignant Thoracic Tumors. Dis. Markers (IF 3.464) Pub Date : 2023-07-12 Disease Markers
[This retracts the article DOI: 10.1155/2021/3265561.].
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Retracted: Association between lncRNA GAS5, MEG3, and PCAT-1 Polymorphisms and Cancer Risk: A Meta-Analysis. Dis. Markers (IF 3.464) Pub Date : 2023-07-12 Disease Markers
[This retracts the article DOI: 10.1155/2020/6723487.].
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Retracted: Distinct Urinary Metabolic Biomarkers of Human Colorectal Cancer. Dis. Markers (IF 3.464) Pub Date : 2023-07-12 Disease Markers
[This retracts the article DOI: 10.1155/2022/1758113.].
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Retracted: Study on the Killing Effect of γδT Cells Activated by Rukangyin on Breast Cancer MDA-MB-231 Cells. Dis. Markers (IF 3.464) Pub Date : 2023-07-12 Disease Markers
[This retracts the article DOI: 10.1155/2021/5838582.].
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Retracted: The Crucial Role of CXCL8 and Its Receptors in Colorectal Liver Metastasis. Dis. Markers (IF 3.464) Pub Date : 2023-07-12 Disease Markers
[This retracts the article DOI: 10.1155/2019/8023460.].
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Retracted: Pathogenic Characterization of a Porcine Circovirus Type 3 Isolate from Heilongjiang, China. Dis. Markers (IF 3.464) Pub Date : 2023-07-12 Disease Markers
[This retracts the article DOI: 10.1155/2021/9434944.].
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Retracted: Therapy Strategy of CD47 in Diffuse Large B-Cell Lymphoma (DLBCL). Dis. Markers (IF 3.464) Pub Date : 2023-07-12 Disease Markers
[This retracts the article DOI: 10.1155/2021/4894022.].
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Aldolase A Promotes Colorectal Cancer Progression through Targeting COPS6 and Regulating MAPK Signaling Pathway Dis. Markers (IF 3.464) Pub Date : 2023-7-6 Ya Lu, Yuan Zhang, Xinyue Wang, Hui Zhang, Yue Zhu, Junying Zhang, Huanhuan Sha, Renrui Zou, Yujie Gan, Ying Sui, Juan Wang, Tongde Du, Jianzhong Wu, Jifeng Feng
Colorectal cancer (CRC) is a serious threat to human health, and its underlying mechanisms remain to be further explored. Aldolase A (ALDOA) has received increasing attention for its reported association with multiple cancers, but the role and mechanisms of ALDOA in CRC are still unclear. In the current study, high expression levels and enzymatic activity of ALDOA were detected in CRC tissues and cell
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Retracted: Efficacy of Laparoscopic Totally Extraperitoneal Repair for Inguinal Hernia. Dis. Markers (IF 3.464) Pub Date : 2023-06-21 Disease Markers
[This retracts the article DOI: 10.1155/2022/2970257.].
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Retracted: Development and Validation of Diagnostic Models for Hand-Foot-and-Mouth Disease in Children. Dis. Markers (IF 3.464) Pub Date : 2023-06-21 Disease Markers
[This retracts the article DOI: 10.1155/2021/1923636.].
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Retracted: Effects of Dexmedetomidine on Postoperative Pain and Recovery Time in Obese Patients. Dis. Markers (IF 3.464) Pub Date : 2023-06-21 Disease Markers
[This retracts the article DOI: 10.1155/2022/9715704.].
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Retracted: BERT-Based Clinical Name Entity Reorganization Model for Health Diagnosis. Dis. Markers (IF 3.464) Pub Date : 2023-06-21 Disease Markers
[This retracts the article DOI: 10.1155/2022/2297063.].
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Retracted: Correlation of Clinicopathological Factors with Brain Tumor-Related Epilepsy in Glioma. Dis. Markers (IF 3.464) Pub Date : 2023-06-21 Disease Markers
[This retracts the article DOI: 10.1155/2022/4918294.].
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Coagulation Dysfunction in Patients with Liver Cirrhosis and Splenomegaly and Its Countermeasures: A Retrospective Study of 1522 Patients Dis. Markers (IF 3.464) Pub Date : 2023-6-7 Yunfu Lv, Ning Liu, Yejuan Li, Jincai Wu, Jinfang Zheng, Xinqiu Li, Min Zeng
Objective. Patients with cirrhosis and splenomegaly often have coagulation dysfunction which affects treatment and prognosis. This study explores the status, grading, and treatment strategies of coagulation dysfunction in patients with liver cirrhosis and splenomegaly. Methods. A retrospective cohort study was conducted on the clinical data on consecutive patients with cirrhosis and splenomegaly treated
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Identifying Hub Genes and miRNA-mRNA Regulatory Networks in Mice Infected with H1N1 Influenza Virus Dis. Markers (IF 3.464) Pub Date : 2023-5-16 Mingyang Li, Qizhi He, Lingli Chen
H1N1 influenza virus is a major factor in seasonal influenza outbreaks. After the body is infected with the influenza virus, the expression of certain mRNAs, including miRNAs, could be affected. However, the association between these mRNAs and miRNAs remains unclear. This study is aimed at identifying differentially expressed genes (DEGs) and miRNAs (DEmiRs) caused by H1N1 influenza virus infection
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Prognostic Factors and Survival of Chinese Patients with Cardiac Amyloidosis Dis. Markers (IF 3.464) Pub Date : 2023-5-16 Lu Zhang, Sulei Li, Bohan Liu, Jing Wang, Yang Mu, Xuan Zhou, Hongbin Liu
Purpose. To identify the survival and prognostic factors for cardiac amyloidosis (CA) in Chinese patients. Methods. This was a prospective cohort study of 72 patients diagnosed with CA and admitted to the PLA General Hospital between November 2017 and April 2021. Demographic, clinical, laboratory, electrocardiographic, conventional ultrasound, endocardial LS during LV systole (LV ENDO LSsys), and myocardial
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Cuproptosis-Related Genes CDK1 and COA6 Involved in the Prognosis Prediction of Liver Hepatocellular Carcinoma Dis. Markers (IF 3.464) Pub Date : 2023-5-11 Sanfeng Han, Tao Ye, Yuqin Mao, Bo Hu, Chen Wang
Background. Liver hepatocellular carcinoma (LIHC) is the most frequently seen type of primary liver cancer. Cuproptosis is a novel form of cell death highly associated with mitochondrial metabolism. However, the clinical impact and pertinent mechanism of cuproptosis genes in LIHC remain largely unknown. Methods. From public databases, we systematically assessed common genes from LIHC differentially
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Low Plasma Levels of Hyaluronic Acid Might Rule Out Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation Dis. Markers (IF 3.464) Pub Date : 2023-4-17 Carmen De Ramón Ortiz, Raul Justo Sanz, Yan Beauverd, Karem Humala, Ana López de la Guia, Raquel De Paz, Mercedes Gasior, Pilar Gómez Prieto, Marta Fabra Urdiola, Miguel Canales Albendea, Nora Butta, Victor Jiménez Yuste
Background. Sinusoidal obstructive syndrome (SOS) is a potentially fatal complication secondary to hematopoietic stem cell transplant (HSCT) conditioning. Endothelial damage plasma biomarkers such as plasminogen activator inhibitor-1 (PAI-1), hyaluronic acid (HA), and vascular adhesion molecule-1 (VCAM1) represent potential diagnostic tools for SOS. Methods. We prospectively collected serial citrated
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Bioinformatics Analysis Identifies EPAS1 as a Novel Prognostic Marker Correlated with Immune Infiltration in Acute Myeloid Leukemia Dis. Markers (IF 3.464) Pub Date : 2023-4-17 Shichun Wang, Pengyu Zhang
EPAS1 plays an important role in the development and progression of multiple tumor types by interacting with a series of other molecules. However, the prognostic and diagnostic values of EPAS1 in acute myeloid leukemia (AML) remain unknown. Here, we systematically explored and clarified the potential functions of EPAS1 in AML using data from Xena Browser and TCGA database. The expression of EPAS1 was
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Erythrocytic, Enzymatic, and Histological Markers of Oxidative Stress in Subacute and Chronic Stage Infections in Wistar Rats (Rattus norvegicus) Infected with Trypanosoma brucei brucei Dis. Markers (IF 3.464) Pub Date : 2023-4-17 Z. Abubakar, N. T. Dabo
Trypanosomiasis is a complex of diseases caused by a haemoprotozoan parasite of medical and veterinary importance. One of the leading factors that cause morbidity and death in trypanosomiasis is oxidative stress. The oxidative stress biomarkers in trypanosomiasis at the subacute and chronic stages of infection were investigated in this study. A total of twenty-four Wistar rats were used; the animals
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NT-proBNP Levels and Collateral Circulation Status in Patients with Acute Ischemic Stroke Dis. Markers (IF 3.464) Pub Date : 2023-4-14 Xiaozhu Shen, Xianxian Zhang, Mengqian Liu, Nan Dong, Juan Liao, Guoqing Zhou, Zhiyong Cao, Liqiang Yu, Yiwen Xu, Yi Jiang, Yue Wan, Qi Fang
Background and Objectives. Strokes resulting from atrial fibrillation (AF) increase with age. The relationship between N-terminal- (NT-) prohormone brain natriuretic peptide (NT-proBNP) level and National Institutes of Health Stroke Scale (NIHSS) score is not well established. Also, the collateral circulation plays an important role in NHISS scores. In this study, the effects of NT-proBNP on collateralization
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Treatment with Antiviral Drugs Will Significantly Inhibit the HIV-1 RNA POL Gene Expression and Viral Load in AIDS Patients Dis. Markers (IF 3.464) Pub Date : 2023-4-14 Penghui Shi, Xiaodong Wang, Miaomiao Su, Juan Meng, Hao Wang, Weiguang Fan
Objective. This study is to investigate the difference in HIV-1 RNA pol gene expression in AIDS patients before and after antiviral treatment and its effect on the expression level of CD4+/CD8+ T cells in peripheral blood. Methods. The participants included 200 AIDS patients who had undergone antiviral medication, and the quantity of HIV-1 RNA pol gene was determined using nested polymerase chain reaction
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The Identification and Clinical Value Evaluation of CYCS Related to Asthma through Bioinformatics Analysis and Functional Experiments Dis. Markers (IF 3.464) Pub Date : 2023-4-14 Yan Li, Li Li, Hua Zhao, Xiwen Gao, Shanqun Li
Background. Asthma is one of the most common respiratory diseases and one of the largest burdens of health care resources across the world. This study is aimed at using bioinformatics methods to find effective clinical indicators for asthma and conducting experimental validation. Methods. We downloaded GSE64913 data and performed differentially expressed gene (DEG) screening. Weighted gene coexpression
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Evaluation of Pleurotus Mushroom Effects on Histopathological Changes in Organs of Diabetic Rats Dis. Markers (IF 3.464) Pub Date : 2023-4-14 Sushil Kumar Dubey, Sachchida Nand Rai, Vinay Kumar Singh, Anand Kumar Bajpeyee, M. P. Singh
Diabetes mellitus (DM) is a metabolic disorder that can be categorized mainly into type 1 and type 2. Diabetes type 1 is caused due to β-cell destruction, whereas type 2 is caused by the resistance of cell receptors. Many therapies are available for the management of diabetes, but they have some side effects, and as a result of this, people are attracted to natural treatments. Pleurotus mushrooms are
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Association between Serum Cys C and PTB Cavitation Dis. Markers (IF 3.464) Pub Date : 2023-4-12 Shumin Tan, Duochi Wu, Yeying Wu, Xing Ren, Jiaxiu Liu, Xiaobin Wei
Background. Cystatin C (Cys C) not only regulates the body’s immune defenses but also contributes to tissue degradation and destruction by causing an imbalance between protease and antiprotease in infectious diseases. Is Cys C involved in pulmonary tuberculosis (PTB) infection and cavitation? We therefore conducted a retrospective study on this question to provide a basis for further studies. Methods
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Identification of Inflammatory Gene in the Congenital Heart Surgery Patients following Cardiopulmonary Bypass via the Way of WGCNA and Machine Learning Algorithms Dis. Markers (IF 3.464) Pub Date : 2023-4-12 Liang Cai, Bingdong Zhang
Performing cardiopulmonary bypass (CPB) to reduce ischemic injury during surgery is a common approach to cardiac surgery. However, this procedure can lead to systemic inflammation and multiorgan dysfunction. Therefore, elucidating the molecular mechanisms of CPB-induced inflammatory cytokine release is essential as a critical first step in identifying new targets for therapeutic intervention. The GSE143780
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Keloid Core Factor CTRP3 Overexpression Significantly Controlled TGF-β1-Induced Propagation and Migration in Keloid Fibroblasts Dis. Markers (IF 3.464) Pub Date : 2023-4-12 Lin He, Chan Zhu, Huicong Dou, Xueyuan Yu, Jing Jia, Maoguo Shu
Purpose. Keloid is a type of benign fibrous proliferative tumor characterized by excessive scarring. C1q/TNF-related protein 3 (CTRP3) has been proven to possess antifibrotic effect. Here, we explored the role of CTRP3 in keloid. In the current research, we examined the influence of CTRP3 on keloid fibroblasts (KFs) and investigated the potential molecular mechanism. Methods. KF tissue specimens and