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Multiple high-risk HPV infections probably associated with a higher risk of low-grade cytological abnormalities but not with high-grade intraepithelial lesions of the cervix World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-14 Tong Tong, Di Su, Qi Yang, Kun Yang, Yuqi Liu, Qun Wang, Tian Tian
For women diagnosed with HR-HPV DNA positivity in community hospitals, the necessity of investigating the potential presence of multiple HR-HPV infections upon referral to tertiary medical institutions remains unclear. In our cohort, women tested positive for HR-HPV DNA during examinations in community hospitals, were subsequently referred to tertiary medical facilities, reevaluated HR-HPV genotype
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Successful multidisciplinary treatment for synchronous advanced esophageal and cecal cancers after total gastrectomy with reconstruction by jejunal interposition World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-14 Yuta Sato, Yoshihiro Tanaka, Kazuo Yamamoto, Takeshi Horaguchi, Masahiro Fukada, Yuki Sengoku, Itaru Yasufuku, Ryuichi Asai, Jesse Yu Tajima, Shigeru Kiyama, Takazumi Kato, Katsutoshi Murase, Nobuhisa Matsuhashi
Esophageal squamous cell carcinoma is characterized by field cancerization, wherein multiple cancers occur in the esophagus, head and neck, and stomach. Synchronous esophageal and colorectal cancers are also encountered with a certain frequency. A good prognosis can be expected if the tumors in both locations can be safely and completely removed. For patients with multiple cancers that occur simultaneously
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Metastatic melanoma to small bowel: metastasectomy is supported in the era of immunotherapy and checkpoint inhibitors World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-11 Paul Wong, Andrew D. Wisneski, Katy K. Tsai, Tammy T. Chang, Kenzo Hirose, Eric K. Nakakura, Adil I. Daud, Ajay V. Maker, Carlos U. Corvera
Metastatic melanoma to the small bowel is an aggressive disease often accompanied by obstruction, abdominal pain, and gastrointestinal bleeding. With advancements in melanoma treatment, the role for metastasectomy continues to evolve. Inclusion of novel immunotherapeutic agents, such as checkpoint inhibitors, into standard treatment regimens presents potential survival benefits for patients receiving
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Renal cell carcinoma with an “uncoiling” tumor thrombus: intraoperative shift from level III to level IV World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-07 Marina Mata, Marina M. Tabbara, Angel Alvarez, Javier González, Gaetano Ciancio
The gold standard treatment for renal cell carcinoma (RCC) with tumor thrombus (TT) is complete surgical excision. The surgery is complex and challenging to the surgeon, especially with large tumor thrombus extending into the inferior vena cava (IVC) and right atrium. Traditionally, these difficult cases required the use of cardiopulmonary bypass (CPB) with or without deep hypothermic cardiac arrest
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The effect of spread through air spaces on postoperative recurrence-free survival in patients with multiple primary lung cancers World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-05 Hongsheng Xie, Shihua Dou, Xiaoxiang Huang, Yuxin Wen, Lin Yang
The purpose of the study was to investigate the effect of spread through air spaces (STAS) on the postoperative prognosis of patients with multiple primary lung cancers staged from IA to IB based on tumor size. Clinicopathological and follow-up data of 122 patients with multiple primary lung cancers diagnosed at stages IA-IB and surgically treated at the Department of Thoracic Surgery, Shenzhen people’s
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Involvement of CX3CR1+ cells appearing in the abdominal cavity in the immunosuppressive environment immediately after gastric cancer surgery World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-04 Seiji Natsuki, Mami Yoshii, Hiroaki Tanaka, Takuya Mori, Sota Deguchi, Yuichiro Miki, Tatsuro Tamura, Takahiro Toyokawa, Shigeru Lee, Kiyoshi Maeda
Gastric cancer is primarily treated by surgery; however, little is known about the changes in the intraperitoneal immune environment and the prognostic impact of surgery. Surgical stress and cancer-associated inflammation cause immune cells to mobilize into the abdominal cavity via numerous cytokines. One such cytokine, CX3CR1, has various immune-related functions that remain to be fully explained
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Application of hand-sewn esophagojejunostomy in laparoscopic total gastrectomy World J. Surg. Onc. (IF 3.2) Pub Date : 2024-03-02 Hao Gu, Weixiang Li, Lianbang Zhou
To investigate the clinical efficacy and prognostic implication of hand-sewn anastomosis in laparoscopic total gastrectomy (LTG). Retrospective analysis is adopted to the clinicopathologic data of 112 patients with gastric cancer (GC) who went through LTG in the Department of General Surgery, the Second Affiliated Hospital of Anhui Medical University between October 2020 and October 2022. Among them
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Mammographically detected breast clustered microcalcifications localized by chest thin-section computed tomography World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-29 Xinjie Liu, Yuhan Bao, Laijian Sui, Jianqiao Cao, Yidan Wang, Chao Yu, Guangdong Qiao, Yizi Cong
To explore the capability and clinical significance of chest thin-section computed tomography (CT) for localization of mammographically detected clustered microcalcifications. A total of 69 patients with 71 mammographically detected clustered microcalcifications received surgical biopsy under the guidance of mammography (MG), CT was used to localize calcifications combined with MG if calcifications
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Smartphone-based inertial measurements during Chester step test as a predictor of length of hospital stay in abdominopelvic cancer postoperative period: a prospective cohort study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-28 Ananda Quaresma Nascimento, Letícia Akemi Rosa Nagata, Manuela Trindade Almeida, Vanessa Ladyanne da Silva Costa, Ana Beatriz Rocha de Marin, Victória Brioso Tavares, Geraldo Ishak, Bianca Callegari, Enzo Gabriel Rocha Santos, Givago da Silva Souza, João Simão de Melo Neto
Objective assessment of pre-operative functional capacity in cancer patients using the smartphone gyroscope during the Chester step (CST) test may allow greater sensitivity of test results. This study has investigated whether the CST is a postoperative hospital permanence predictor in cancer patients undergoing abdominopelvic surgery through work, VO2MAX and gyroscopic movement analysis. Prospective
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Meta-analysis of clinical efficacy of thoracoscopy and robotic surgery in the treatment of mediastinal tumors World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-28 Jiying Dang, Shize Sun, Zhengqi Wu, Yidong Shan, Huiling Zhang
Comparing the clinical efficacy of thoracoscopy and robotic surgery in the treatment of mediastinal tumors using meta-analysis. Computer retrieval of PubMed, Embase, The Cochrane Library, and Web of Science databases for literature comparing the clinical effects of video-assisted thoracic surgery (VATS) and robot-assisted thoracic surgery (RATS) in treating mediastinal tumors, with the retrieval time
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Efficacy and safety of direct oral anticoagulants versus low-molecular-weight heparin for thromboprophylaxis after cancer surgery: a systematic review and meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-26 Hong Zhou, Ting-Ting Chen, Ling-ling Ye, Jun-Jie Ma, Jin-Hua Zhang
Direct oral anticoagulants (DOACs) used as an alternative to low-molecular-weight heparin (LMWH) for thromboprophylaxis after cancer surgery for venous thromboembolic events (VTE) remains unclear. This study aimed to investigate the efficacy and safety of DOACs versus LMWH in these patients. A search of EMBASE, MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science was
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The role and controversy of pelvic lymph node dissection in prostate cancer treatment: a focused review World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-26 Baonan Dong, Hui Zhan, Ting Luan, Jiansong Wang
Pelvic lymph node dissection (PLND) is commonly performed alongside radical prostatectomy. Its primary objective is to determine the lymphatic staging of prostate tumors by removing lymph nodes involved in lymphatic drainage. This aids in guiding subsequent treatment and removing metastatic foci, potentially offering significant therapeutic benefits. Despite varying recommendations from clinical practice
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Predictive accuracy of boosted regression model in estimating risk of venous thromboembolism following minimally invasive radical surgery in pharmacological prophylaxis-naïve men with prostate cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-23 Chie Hui Leong, Sushil Rodrigues Ranjan, Anna Javed, Basim S.O. Alsaedi, Ghulam Nabi
Venous thromboembolism (VTE) is a potentially life-threatening but preventable complication after urological surgery. Physicians are faced with the challenges of weighing the risks and benefits of thromboprophylaxis given scanty evidence for or against and practice variation worldwide. The primary objective of the study was to explore the possibility of a risk-stratified approach for thromboembolism
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Is there any difference in urinary continence between bilateral and unilateral nerve sparing during radical prostatectomy? A systematic review and meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-23 Peng Xiang, Zhen Du, Di Guan, Wei Yan, Mingdong Wang, Danyang Guo, Dan Liu, Yuexin Liu, Hao Ping
In men with prostate cancer, urinary incontinence is one of the most common long-term side effects of radical prostatectomy (RP). The recovery of urinary continence in patients is positively influenced by preserving the integrity of the neurovascular bundles (NVBs). However, it is still unclear if bilateral nerve sparing (BNS) is superior to unilateral nerve sparing (UNS) in terms of post-RP urinary
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Clinical characteristics and prognostic analysis of postoperative recurrence or metastasis of low-risk gastrointestinal stromal tumors World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-23 Lianlian Cao, Chen Lin, Yu Liu, Chao Sui, Zhaoping Li, Li Chen, Wenxian Guan, Liang Tao, Tingting Tao, Meng Wang, Feng Wang
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract. This study aimed to investigate the clinical characteristics and prognosis of postoperative recurrence or metastasis in patients with low-risk stromal tumors, in order to take individualized postoperative management and treatment for patients with low-risk GISTs with relatively high recurrence. We
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Preoperative serum level of CA153 and a new model to predict the sub-optimal primary debulking surgery in patients with advanced epithelial ovarian cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-23 Yue Jia, Yaping Jiang, Xiaoqi Fan, Ya Zhang, Kun Li, Haohan Wang, Xianling Ning, Xielan Yang
The aim of this study was to establish a preoperative model to predict the outcome of primary debulking surgery (PDS) for advanced ovarian cancer (AOC) patients by combing Suidan predictive model with HE4, CA125, CA153 and ROMA index. 76 AOC Patients in revised 2014 International Federation of Gynecology and Obstetrics (FIGO) stage III-IV who underwent PDS between 2017 and 2019 from Yunnan Cancer Hospital
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A case report of carcinoma of the papilla of Vater associated with a hyperplasia–dysplasia–carcinoma sequence by pancreaticobiliary maljunction World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-22 Takahiro Korai, Yasutoshi Kimura, Kazunori Watanabe, Siew-Kee Low, Masafumi Imamura, Minoru Nagayama, Kazuharu Kukita, Takeshi Murakami, Toru Kato, Yuta Kondo, Daisuke Kyuno, Taro Sugawara, Ayako Murota, Yujiro Kawakami, Yoshiharu Masaki, Hiroshi Nakase, Ichiro Takemasa
Pancreaticobiliary maljunction (PBM) is a known risk factor for biliary tract cancer. However, its association with carcinoma of the papilla of Vater (PVca) remains unknown. We report a case with PVca that was thought to be caused by the hyperplasia–dysplasia–carcinoma sequence, which is considered a mechanism underlying PBM-induced biliary tract cancer. A 70-year-old woman presented with white stool
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Laparoscopic versus laparotomic surgical treatment in apparent stage I ovarian cancer: a multi-center retrospective cohort study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-22 Jing Zhang, Meiyan Li, Lan Feng, Yinjun Zhai, Lin Wang, Yuancao Chen
Laparoscopic treatment shows non-inferior survival outcomes and better surgical outcomes in apparent stage I ovarian cancer (OC) in some studies but has not been well defined. We conducted a retrospective study of patients with apparent stage I OC treated in two hospitals between 2012 and 2022. The surgical and oncologic outcomes were evaluated between patients receiving laparoscopic and laparotomic
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Association of preoperative muscle-adipose index measured by computed tomography with survival in patients with esophageal squamous cell carcinoma World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-22 Danqi Qian, Peipei Shen, Jiahao Zhu, Shengjun Ji, Yan Kong
Conventional nutritional metrics are closely associated with the prognosis of patients with radically resected esophageal squamous cell carcinoma (ESCC). Nevertheless, the prognostic implications of muscle and adipose tissue composite indexes in ESCC remain unknown. We retrospectively analyzed clinicopathological data of 304 patients who underwent resected ESCC. To obtain measurements of the muscle
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Radiation-induced cutaneous vasculopathy of the breast: a rare case report World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-21 Hilde Van Parijs, Yves Sinove, Marilyn Carprieaux, Mark De Ridder
Radiation therapy is often indicated as part of the treatment for breast cancer and is therefore used frequently worldwide. Vasculopathy is a general term used to describe any condition that affects blood vessels. We present a case report of a patient who presented with vasculopathy as a rare late side effect of radiation therapy to the breast. This 66-year-old woman was initially treated with breast-conserving
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Younger patients with colorectal cancer may have better long-term survival after surgery: a retrospective study based on propensity score matching analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-21 Weihao Liao, Yuanxi Li, Yuheng Zou, Qinchen Xu, Xiaodong Wang, Li Li
The relationship between postoperative long-term prognosis and age in colorectal cancer patients remains controversial. The purpose of this study based on a Chinese CRC cohort is to determine the disparity in long-term survival outcomes between younger and older colorectal cancer (CRC) patients after surgery using a propensity score matching (PSM). Data for this study was derived from the CRC cohort
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Survival analysis of laparoscopic surgery and open surgery for hilar cholangiocarcinoma: a retrospective cohort study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-19 Yaolin Yin, Jilin Tao, Yin Xian, Junhao Hu, Yonghe Li, Qiang Li, Yongfu Xiong, Yi He, Kun He, Jingdong Li
This study compared the clinical efficacy and safety of laparoscopic versus open resection for hilar cholangiocarcinoma (HCCA) and analyzed potential prognostic factors. The study included patients who underwent HCCA resection at our center from March 2012 to February 2022. Perioperative complications and postoperative prognosis were compared between the laparoscopic surgery (LS) and open surgery (OS)
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C-Myc protein expression indicates unfavorable clinical outcome in surgically resected small cell lung cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-19 Christian Lang, Zsolt Megyesfalvi, Andras Lantos, Felicitas Oberndorfer, Mir Alireza Hoda, Anna Solta, Bence Ferencz, Janos Fillinger, Anna Solyom-Tisza, Alessandro Saeed Querner, Felix Egger, Kristiina Boettiger, Thomas Klikovits, Gerald Timelthaler, Ferenc Renyi-Vamos, Clemens Aigner, Konrad Hoetzenecker, Viktoria Laszlo, Karin Schelch, Balazs Dome
By being highly involved in the tumor evolution and disease progression of small cell lung cancer (SCLC), Myc family members (C-Myc, L-Myc, and N-Myc) might represent promising targetable molecules. Our aim was to investigate the expression pattern and prognostic relevance of these oncogenic proteins in an international cohort of surgically resected SCLC tumors. Clinicopathological data and surgically
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Comparison of liver resection and radiofrequency ablation in long-term survival among patients with early-stage hepatocellular carcinoma: a meta-analysis of randomized trials and high-quality propensity score-matched studies World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-19 Lingbo Hu, Jiangying Lin, Aidong Wang, Xingpeng Shi, Yingli Qiao
Whether radiofrequency ablation (RFA) and liver resection (LR) are comparable treatments for early-stage hepatocellular carcinoma (HCC) is controversial. We conducted this study to provide ample clinical evidence for the argument. The PubMed, Embase, Web of Science, and Cochrane Library databases were systematically searched to identify randomized controlled trials (RCTs) and propensity score-matched
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A MRI radiomics-based model for prediction of pelvic lymph node metastasis in cervical cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-17 Tao Wang, Yan-Yu Li, Nan-Nan Ma, Pei-An Wang, Bei Zhang
Cervical cancer (CC) is a common malignancy of the female reproductive tract, and preoperative prediction of lymph node metastasis (LNM) is essential. This study aims to design and validate a magnetic resonance imaging (MRI) radiomics-based predictive model capable of detecting LNM in patients diagnosed with CC. This retrospective analysis incorporated 86 and 38 CC patients into the training and testing
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Analgesic efficacy of an opioid-free postoperative pain management strategy versus a conventional opioid-based strategy following laparoscopic radical gastrectomy: an open-label, randomized, controlled, non-inferiority trial World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-15 Zhimin Lin, Zhongbiao Chen, Yongliang Li
In patients undergoing laparoscopic radical gastrectomy, the use of subcostal transversus abdominis plane block (STAPB) for completely opioid-free postoperative pain management lacks convincing clinical evidence. This study included 112 patients who underwent laparoscopic radical gastrectomy at the 900TH Hospital of the Joint Logistics Support Force from October 2020 to March 2022. Patients were randomly
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Surgical outcomes after reoperation for patients with recurrent presacral tumors: a retrospective study World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-15 Rui Li, Zhiyuan Yu, Jiahu Ye, Xin Liu, Peiyu Li, Xudong Zhao
Relevant reports on the surgical resection and prognosis of recurrent presacral tumors are limited. The objective of this study was to explore the outcomes associated with surgical resection of recurrent presacral tumors. The data of patients with recurrent presacral tumors who received surgical resection in our hospital between June 2009 and November 2018 were retrospectively analyzed. Thirty-one
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Advances in the assessment of cosmetic outcomes, sensory alteration in surgical areas, and health-related quality of life of endoscopic thyroidectomy World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-13 Di Zhou, Zeyu Zhang, Xiaolin Dou, Fada Xia, Xinying Li
Endoscopic thyroidectomy has been preliminarily proven effective and safe for thyroid diseases. The cosmetic outcomes and life quality are critical contents of postoperative assessment. This review will primarily focus on the assessment methods and results related to cosmetic outcomes, sensory alteration of surgical area, and quality of life following endoscopic thyroidectomy. A comprehensive search
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Presurgical computed tomography-guided localization of lung ground glass nodules: comparing hook-wire and indocyanine green World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-10 Rui Han, Long-Fei Wang, Fei Teng, Jia Lin, Yu-Tao Xian, Yun Lu, An-Le Wu
Presurgical computed tomography (CT)-guided localization is frequently employed to reduce the thoracotomy conversion rate, while increasing the rate of successful sublobar resection of ground glass nodules (GGNs) via video-assisted thoracoscopic surgery (VATS). In this study, we compared the clinical efficacies of presurgical CT-guided hook-wire and indocyanine green (IG)-based localization of GGNs
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Case report of penile squamous cell carcinoma continuous treatment with BRCA2 mutation World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-09 Qing Zhang, Yaping Li, Yanrui Zhang, Zhiping Deng, Yi Ding
Penile squamous cell carcinoma (PSCC) is a highly aggressive malignancy with a poor prognosis. BRCA1/2 mutations are associated with impaired DNA double-strand break repair and are among the common mutations in penile cancer, potentially paving the way for poly ADP-ribose polymerase inhibitor therapy. We report a 65-year-old male with PSCC who progressed to thigh metastasis at 10 months after partial
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Individualized detection of TMPRSS2-ERG fusion status in prostate cancer: a rank-based qualitative transcriptome signature World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-09 Yawei Li, Hang Su, Kaidong Liu, Zhangxiang Zhao, Yuquan Wang, Bo Chen, Jie Xia, Huating Yuan, De-Shuang Huang, Yunyan Gu
TMPRSS2-ERG (T2E) fusion is highly related to aggressive clinical features in prostate cancer (PC), which guides individual therapy. However, current fusion prediction tools lacked enough accuracy and biomarkers were unable to be applied to individuals across different platforms due to their quantitative nature. This study aims to identify a transcriptome signature to detect the T2E fusion status of
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Preoperative predictors for non-resectability in perihilar cholangiocarcinoma World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-07 Carlos Constantin Otto, Anna Mantas, Lara Rosaline Heij, Daniel Heise, Maxime Dewulf, Sven Arke Lang, Tom Florian Ulmer, Edgar Dahl, Philipp Bruners, Ulf Peter Neumann, Jan Bednarsch
Explorative laparotomy without subsequent curative-intent liver resection remains a major clinical problem in the treatment of perihilar cholangiocarcinoma (pCCA). Thus, we aimed to identify preoperative risk factors for non-resectability of pCCA patients. Patients undergoing surgical exploration between 2010 and 2022 were eligible for the analysis. Separate binary logistic regressions analyses were
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Efficacy and safety of laparoscopic liver resection versus radiofrequency ablation in patients with early and small hepatocellular carcinoma: an updated meta-analysis and meta-regression of observational studies World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-07 Mahmoud Shaaban Abdelgalil, Basma Ehab Amer, Noha Yasen, Mohamed El-Samahy, Ahmed K. Awad, Bahaa Elfakharany, Omar Saeed, Mohamed Abd-ElGawad
Hepatocellular carcinoma (HCC) is the most common type of liver cancer, accounting for 90% of cases worldwide and a significant contributor to cancer-related deaths. This study comprehensively compares the safety and efficacy of laparoscopic liver resection (LLR) versus laparoscopic or percutaneous radiofrequency ablation (LRFA or PRFA) in patients with early and small HCC. We systematically searched
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Identification of predictors for short-term recurrence: comprehensive analysis of 296 retroperitoneal liposarcoma cases World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-06 Zhiyuan Yu, Rui Li, Zhen Yuan, Jiahu Ye, Ping He, Peiyu Li, Yan Sun, Xudong Zhao
The short-term (≤ 1 year) recurrence (STR) is the primary determinant impacting both the life quality and survival duration in patients who have undergone surgical resection for retroperitoneal liposarcoma (RPLS), a condition with intricate and ambiguous pathogenesis. The purpose of this study was to analyze the risk factors associated with STR in cases of RPLS and primary retroperitoneal liposarcoma
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Safety and efficacy of stoma site selection in CT-guided percutaneous gastrostomy: a retrospective analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-06 Hu Chang-ming, Qi Xiao-mei, Liu Li, Liang Qing-Hua, Xiong Jun-ru, Li Liang-shan, Deng Liang-yu, Huang Xue-quan, He Chuang
To compare the safety and efficacy of CPG in the rectus abdominis and intercostal regions. This retrospective study included 226 patients who underwent CPG at a single center, with the stoma placed in the rectus abdominis or intercostal region. Surgical outcomes and complications, such as pain and infection within 6 months postoperatively, were recorded. The surgical success rate was 100%, and the
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CD47—a novel prognostic predicator in epithelial ovarian cancer and correlations with clinicopathological and gene mutation features World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-06 Xukai Luo, Jiahang Mo, Min Zhang, Wu Huang, Yiting Bao, Ruoyao Zou, Liangqing Yao, Lei Yuan
Epithelial ovarian cancer (EOC) is insensitive to immunotherapy due to its poor immunogenicity; thus, suitable biomarkers need to be identified for better prognostic stratification and individualized treatment. CD47 is a novel immunotherapy target; however, its impact on EOC prognosis is controversial and correlation with genetic features is unclear. The aim of this study was to investigate the prognostic
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Textbook oncologic outcomes are associated with increased overall survival in patients with pancreatic head cancer after undergoing laparoscopic pancreaticoduodenectomy World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-06 Jing Zhang, He Cai, Man Zhang, Xin Wang, Yunqiang Cai, Bing Peng
Textbook oncologic outcomes (TOO) have been used to evaluate long-term oncologic outcomes for patients after pancreaticoduodenectomy (PD) but not laparoscopic pancreaticoduodenectomy (LPD). The aim of the study was to assess the prognostic value of TOO for patients with pancreatic head cancer undergoing LPD and discuss the risk factors associated with achieving TOO. Patients with pancreatic head cancer
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The management of uterine tumor resembling an ovarian sex cord tumor (UTROSCT): case series and literature review World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-03 Jie Lin, Linying Liu, Linghua Wang, Ning Ma, Kailin Zhang, Ning Xie, Haijuan Yu, Sufang Deng, Yang Sun
To present a case series of 11 rare uterine tumors resembling ovarian sex cord tumors (UTROSCTs), and review the literature on this topic to offer up-to-date treatment management for UTROSCTs. Eight cases from Fujian Cancer Hospital between January 2017 and May 2023 and three patients from Fujian Union Hospital between October 2012 and October 2020 were retrospectively reviewed. All cases were pathologically
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Prognostic factors for invasive mucinous adenocarcinoma of the lung: systematic review and meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-02 Ting Zhao, Jianhua Yi, Dan Luo, Junjun Liu, Xianming Fan, Qibiao Wu, Wenjun Wang
Invasive mucinous adenocarcinoma of the lung (IMA) is a unique and rare subtype of lung adenocarcinoma with poorly defined prognostic factors and highly controversial studies. Hence, this study aimed to comprehensively identify and summarize the prognostic factors associated with IMA. A comprehensive search of relevant literature was conducted in the PubMed, Embase, Cochrane, and Web of Science databases
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The value of machine learning approaches in the diagnosis of early gastric cancer: a systematic review and meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-02-01 Yiheng Shi, Haohan Fan, Li Li, Yaqi Hou, Feifei Qian, Mengting Zhuang, Bei Miao, Sujuan Fei
The application of machine learning (ML) for identifying early gastric cancer (EGC) has drawn increasing attention. However, there lacks evidence-based support for its specific diagnostic performance. Hence, this systematic review and meta-analysis was implemented to assess the performance of image-based ML in EGC diagnosis. We performed a comprehensive electronic search in PubMed, Embase, Cochrane
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Optimal peritoneal cancer index cutoff point for predicting surgical resectability of pseudomyxoma peritonei in treatment-naive patients World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-31 Mingjian Bai, Yunxiang Li, Hairong Pu, Yueming Xu, Jingliang Chen, Hongbin Xu, Hongjiang Wei, Guowei Liang, Ruiqing Ma, Jing Feng
The peritoneal cancer index (PCI) has been used to predict surgical outcomes for pseudomyxoma peritonei (PMP). The present study aimed to establish the optimal cutoff point for PCI to predict surgical resectability of PMP. A total of 366 PMP patients were included. The patients were divided into low-grade and high-grade groups. Based on the completeness of the cytoreduction (CC) score, both low-grade
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Association between preoperative sarcopenia and prognosis of pancreatic cancer after curative-intent surgery: a updated systematic review and meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-30 Chenming Liu, Liang An, Siyuan Zhang, Shiqing Deng, Neng Wang, Haijun Tang
Sarcopenia is associated with poor outcomes in many malignancies. However, the relationship between sarcopenia and the prognosis of pancreatic cancer has not been well understood. The aim of this meta-analysis was to identify the prognostic value of preoperative sarcopenia in patients with pancreatic cancer after curative-intent surgery. Database from PubMed, Embase, and Web of Science were searched
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The impact of lymphadenectomy on ovarian clear cell carcinoma: a systematic review and meta-analysis World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-29 Yan Liu, Feng Geng, Hongyang Zhang, Jing Xue, Ran Chu
Ovarian clear cell carcinoma (OCCC) shares treatment strategies with epithelial ovarian cancer (EOC). Due to OCCC's rarity, there's a lack of prospective studies on its surgery, resulting in heterogeneous and limited existing data. This study aims to clarify the prognostic significance of lymphadenectomy in OCCC patients. We systematically searched Web of Science, Scopus, PubMed, and Google Scholar
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Association of a novel frameshift variant and a known deleterious variant in MMR genes with Lynch syndrome in Chinese families World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-27 Juyi Li, Haichun Ni, Xiufang Wang, Wenzhuo Cheng, Li Li, Yong Cheng, Chao Liu, Yuanyuan Li, Aiping Deng
Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome. This condition is characterized by germline variants in DNA mismatch repair (MMR) genes, including MLH1, MSH2, MSH6, and PMS2. In this study, we analyzed the molecular defects and clinical manifestations of two families affected with CRC and proposed appropriate individual preventive strategies for all carriers of the
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Multivariate analysis of prognostic factors in patients with lip squamous cell carcinoma after surgery World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-26 Hao Cheng, Jin-Hong Xu, Jia-Qi He, Xi-Yang Yang, Xu-Ning Shen, Xue-Lian Xu
Lip squamous cell carcinoma (LSCC) was one of the most common cancer types of head and neck tumors. This study aimed to find more predictors of the prognosis in postoperative LSCC patients. A total of 147 LSCC patients between June 2012 and June 2018 were collected from two tertiary care institutions. There were 21 clinicopathological factors included and analyzed in our study. The univariate and multivariate
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IFIT3 accelerates the progression of head and neck squamous cell carcinoma by targeting PD-L1 to activate PI3K/AKT signaling pathway World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-25 Peng Liu, Xin Kong, Shijiang Yi, Ying Chen, Wenlong Luo
Emerging evidence has shown interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) may be predicted to be a candidate oncogene and involved in the onset and progression of cancer, but IFIT3’s potential role in cancer, particularly in head and neck squamous cell carcinoma (HNSC), is not well recognized. This study aims to reveal the role of IFIT3 in HNSC and the underlying molecular mechanism
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Inactivation and replantation of the knee joint: an infeasible surgical method World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-25 Zhichao Tian, Yang Yang, Peng Zhang, Xin Wang, Weitao Yao
The inactivation and replantation of autologous tumor bones are important surgical methods for limb salvage in patients with malignancies. Currently, there are few reports on the inactivation and replantation of the knee joint. In this study, we aimed to evaluate the feasibility of our surgical approach. This is a retrospective case series study. We retrospectively collected the clinical data of patients
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Prognostic significance and survival benefits of postoperative adjuvant chemotherapy in patients with stage IA lung adenocarcinoma with non-predominant micropapillary components World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-25 Rongyang Li, Jianhao Qiu, Zhenyi Li, Haiming Li, Zhanpeng Tang, Wenhao Yu, Hui Tian, Zhenguo Sun
The prognostic significance of adjuvant chemotherapy (ACT) for patients with stage IA micropapillary non-predominant (MPNP) lung adenocarcinoma (LUAD) remains unknown. This study aimed to investigate the effects of postoperative ACT in patients with stage IA MPNP-LUAD. A total of 149 patients with pathological stage IA MPNP-LUAD who underwent surgery at our center were retrospectively analyzed. Propensity
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Effect of adjuvant chemotherapy on the oncological outcome of rectal cancer patients with pathological complete response World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-25 Jianguo Yang, Qican Deng, Yong Cheng, Zhongxue Fu, Xin Wu
Locally advanced rectal cancer is typically treated using a combination of neoadjuvant chemoradiotherapy and total mesorectal resection. While achieving pathological complete response following neoadjuvant chemoradiotherapy has been recognized as a positive prognostic factor in oncology, the necessity of adjuvant chemotherapy for locally advanced rectal cancer patients with pathological complete response
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Association between postoperative pathological results and non-sentinel nodal metastasis in breast cancer patients with sentinel lymph node-positive breast cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-24 Lingguang Dong, Suosu Wei, Zhen Huang, Fei Liu, Yujie Xie, Jing Wei, Chongde Mo, Shengpeng Qin, Quanqing Zou, Jianrong Yang
For patients with 1–2 positive sentinel lymph nodes (SLN) identified by biopsy, the necessity of axillary lymph node dissection (ALND) remains a matter of debate. The primary aim of this study was to investigate the association between postoperative pathological factors and non-sentinel lymph node (NSLN) metastases in Chinese patients diagnosed with sentinel node-positive breast cancer. This research
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Risk factors and prognosis of malignant peritoneal mesothelioma with paraneoplastic syndrome World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-24 Xin-Li Liang, Yan-Dong Su, Xin-Bao Li, Yu-Bin Fu, Ru Ma, Rui Yang, He-Liang Wu, Yan Li
Malignant peritoneal mesothelioma (MPM) is a rare and highly aggressive tumor. Its clinical manifestations are diverse, and the symptoms are not specific. Some patients will develop paraneoplastic syndrome (PS) during the disease course. This study aims to analyze the risk factors of PS in patients with MPM and their impacts on prognosis. The clinical data of MPM patients who underwent cytoreductive
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Malignant myoepithelioma of the external auditory canal — a rare case report with literature review and clinical importance of foramen of Huschke World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-24 Zuzana Mateášiková, Richard Salzman, Jaroslav Michálek
A malignant myoepithelioma is a rare tumor, mostly arising from the salivary glands. Myoepitheliomas of the ear have rarely been reported. The manuscript reports myoepithelial carcinoma of the external auditory canal (EAC) spreading to the infratemporal fossa. A clinician must be aware of anatomical variation of the bony EAC wall, such as the foramen of Huschke. This rare defect may be a pathway for
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Correlation between sarcopenia and esophageal cancer: a narrative review World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-24 Shenglan Li, Kaiqiang Xie, Xiaoxiong Xiao, Pingsheng Xu, Mimi Tang, Dai Li
In recent years, the research on the relationship between sarcopenia before and after the treatment of esophageal cancer, as well as its impact on prognosis of esophageal cancer, has increased rapidly, which has aroused people’s attention to the disease of patients with esophageal cancer complicated with sarcopenia. This review examines the prevalence of sarcopenia in patients with esophageal cancer
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Re-exploration of prognosis in type B thymomas: establishment of a predictive nomogram model World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-23 Ke Zhao, Lei Liu, Xiaoyun Zhou, Guige Wang, Jiaqi Zhang, Xuehan Gao, Libing Yang, Ke Rao, Chao Guo, Ye Zhang, Cheng Huang, Hongsheng Liu, Shanqing Li, Yeye Chen
To explore the risk factors for disease progression after initial treatment of type B thymomas using a predictive nomogram model. A single-center retrospective study of patients with type B thymoma was performed. The Cox proportional hazard model was used for univariate and multivariate analyses. Variables with statistical and clinical significance in the multivariate Cox regression were integrated
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Immune characteristics of dedifferentiated retroperitoneal liposarcomas and the reliability of regional samples in evaluating their tumor immune microenvironments World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-23 Changsheng Zhou, Ming Li, Yantao Ren, Fenglin Miao, Yue Wang, Ting Wu, Xin Gou, Wengang Li
Tumor immunotherapy is a new treatment breakthrough for retroperitoneal liposarcoma (RPLS), which is highly invasive and has few effective treatment options other than tumor resection. However, the heterogeneity of the tumor immune microenvironment (TIME) leads to missed clinical diagnosis and inappropriate treatment. Therefore, it is crucial to evaluate whether the TIME of a certain part of the tumor
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Patients with high nuclear grade pT1-ccRCC are more suitable for radical nephrectomy than partial nephrectomy: a multicenter retrospective study using propensity score World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-23 Haozhe Xu, Zhuo Xing, Kai Ai, Jie Wang, Zhengtong Lv, Haitao Deng, Ke Li, Yang Wang, Yuan Li
Partial nephrectomy (PN) is usually recommended for T1 stage clear cell renal cell carcinoma (ccRCC) regardless of the nuclear grades. However, the question remains unresolved as to whether PN is non-inferior to RN in patients with T1-ccRCC at higher risk of recurrence. In fact, we found that patients with high nuclear grades treated with PN had poorer prognosis compared with those treated with radical
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Mortality and morbidity after colorectal cancer resection surgery in elderly patients: a retrospective population-based study in Sweden World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-22 Maria Normann, Niklas Ekerstad, Eva Angenete, Mattias Prytz
Colorectal cancer is primarily a condition of older adults, and surgery is the cornerstone of treatment. As life expectancy is increasing and surgical techniques and perioperative care are developing, curative surgery is often conducted even in ageing populations. However, the risk of morbidity, functional decline, and mortality following colorectal cancer resection surgery are known to increase with
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Transforming growth factor-induced gene TGFBI is correlated with the prognosis and immune infiltrations of breast cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-20 Haiwei Wang, Xinrui Wang, Liangpu Xu
Transforming growth factor β (TGFβ) is a critical regulator of lung metastasis of breast cancer and is correlated with the prognosis of breast cancer. However, not all TGFβ stimulated genes were functional and prognostic in breast cancer lung metastatic progress. In this study, we tried to determine the prognosis of TGFβ stimulated genes in breast cancer. TGFβ stimulated genes in MDA-MB-231 cells and
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Development and validation of nomogram for predicting early recurrence after radical gastrectomy of gastric cancer World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-19 Mengxuan Cao, Can Hu, Siwei Pan, Yanqiang Zhang, Pengcheng Yu, Ruolan Zhang, Xiangdong Cheng, Zhiyuan Xu
After radical surgery, early detection of recurrence and metastasis is a crucial factor in enhancing the prognosis and survival of patients with gastric cancer (GC). Therefore, assessing the risk of recurrence in gastric cancer patients and determining the timing for postoperative recurrence is crucial. The clinicopathological data of 521 patients with recurrent gastric cancer, who underwent radical
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Clinical evaluation of augmented reality-based 3D navigation system for brachial plexus tumor surgery World J. Surg. Onc. (IF 3.2) Pub Date : 2024-01-17 Xuanyu Zhao, Huali Zhao, Wanling Zheng, Andreas Gohritz, Yundong Shen, Wendong Xu
Augmented reality (AR), a form of 3D imaging technology, has been preliminarily applied in tumor surgery of the head and spine, both are rigid bodies. However, there is a lack of research evaluating the clinical value of AR in tumor surgery of the brachial plexus, a non-rigid body, where the anatomical position varies with patient posture. Prior to surgery in 8 patients diagnosed with brachial plexus