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RWC Update: Macular Indentation to Manage Complications of Pathological Myopia; OCT Biomarker Based Decision Making in the Management of Diabetic Macular Edema; Scleritis With Chorioretinal Folds. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-11-01 Ashish Sharma,Lihteh Wu,Steven Bloom,Paulo Stanga,Inder P Singal,Khalid Al Sabti,Riccardo Sacconi,Giuseppe Querques,Jay Chhablani,Will Gibson,Kourous A Rezaei
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Optimizing Visual Outcomes in Patients With Neovascular Age-Related Macular Degeneration: the Potential Value of Sustained Anti-VEGF Therapy. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-11-01 Christina Y Weng,Rishi P Singh,Mark C Gillies,Carl D Regillo
Neovascular age-related macular degeneration (nAMD) leads to irreversible central vision loss if untreated. Frequent administration of anti-vascular endothelial growth factor (anti-VEGF) injections inhibits disease activity with excellent functional and morphological benefits. However, these injections pose a heavy therapeutic burden, and treatment discontinuation is common. Although current anti-VEGF
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Distribution of Neurofilament in Peeled Internal Limiting Membrane. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-11-01 Sanghyup Lee,Dae Hyuk You,Soojung Park,Hyun Sub Oh,Oh Woong Kwon
BACKGROUND AND OBJECTIVE The aim was to study the distribution of neurofilament in peeled internal limiting membrane (ILM). PATIENTS AND METHODS Prospective case study. Vitrectomy and ILM peeling were performed in patients with epiretinal membrane and macular hole. ILM flap specimens were obtained as one disc area size from five locations. Immunofluorescent staining was performed with an antineurofilament
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Impact of Dyslipidemia Medications on the Prevalence of Diabetic Retinopathy Among a Large US Cohort. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-11-01 Srila H Chadalavada,Jacqueline K Shaia,Matthew W Russell,Katherine E Talcott,Rishi P Singh
BACKGROUND AND OBJECTIVE Dyslipidemia medications such as statins and fibrates may be associated with a reduction in diabetic retinopathy (DR) progression, but real-world data is lacking. This study evaluates cholesterol-lowering medications and their association with the prevalence of DR and advanced DR complications. PATIENTS AND METHODS Data was collected using codes from the International Classification
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Patients With Dragged Optic Disc Vessels and Retinal Folds: Clinical Features, Multimodal Imaging, and Histopathology. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-11-01 Prashanth G Iyer,Noy Ashkenazy,Piero Carletti,Julia L Hudson,Nimesh A Patel,Jesse D Sengillo,Anne L Kunkler,Thomas A Lazzarini,Rayan Abou Khzam,Vincent Tang,Catherin I Negron,Sander Dubovy,Harry W Flynn,Audina M Berrocal
BACKGROUND AND OBJECTIVE To describe the multimodal imaging and histopathological features of patients with dragged optic disc vessels (DODV). PATIENTS AND METHODS This is a retrospective, observational analysis using multimodal imaging of eyes with DODV in patients with retinal vascular diseases including familial exudative vitreoretinopathy, inflammatory disease, and others. In addition, two additional
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Severe Retinal Displacement With Peripheral Retinal Fold Following Vitrectomy Combined With Scleral Buckle. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-11-01 Isabela M Melo,Sumana Naidu,Rajeev H Muni
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Trends in Imaging Utilization Among United States Medicare Beneficiaries and the Impact of the COVID-19 Pandemic. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-11-01 Avni P Finn,Xiangyu Ji,Qingxia Chen,Paul Sternberg,Shriji Patel
This study characterizes trends in ophthalmic imaging volume and utilization in the United States among and assesses the potential impact of the COVID-19 pandemic using data from the Centers for Medicare and Medicaid Services. Utilization of macular optical coherence tomography (OCT), optic nerve OCT, and fundus photography steadily increased from 2013 to 2020 and was not impacted by the COVID-19 pandemic
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Treatments for Acute Nonarteritic Central Retinal Artery Occlusion: Findings From a Cochrane Systematic Review. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-11-01 John C Lin,Sophia L Song,Sueko M Ng,Ingrid U Scott,Paul B Greenberg
Many interventions for nonarteritic central retinal artery occlusion (CRAO) are associated with serious complications and little effect on visual outcomes. We report on the findings of a Cochrane systematic review that searched seven databases for peer-reviewed articles reporting on treatments for acute nonarteritic CRAO. We assessed six randomized controlled trials, including interventions such as
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Open Globe Injuries From Garage Door Springs. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-11-01 Priya P Shah,Romy Bejjani,Panisa Singhanetr,Neal S Patel,Nimesh A Patel,Grayson W Armstrong,Elizabeth J Rossin
We describe seven patients who were attempting to repair their garage door when a spring dislodged at high velocity, resulting in open globe injury. All patients were seen at Massachusetts Eye and Ear between the years 2008 and 2023. Their final visual acuities ranged from 20/125 to no light perception. Open globe injury appears to be a risk of attempts to repair a garage door by people who are inexperienced
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Diagnosis and Management of Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Delphi Consensus Exercise. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-10-01 Rishi P Singh,Winfried Amoaku,Francesco Bandello,Fred K Chen,Frank G Holz,Laurent Kodjikian,José M Ruiz-Moreno,Preeti Joshi,Charles C Wykoff
Geographic atrophy (GA) is a progressive and irreversible retinal disease with no comprehensive recommendations for diagnosis or monitoring. We used a Delphi approach to determine consensus in key areas around diagnosis and management of GA. A steering committee of eight retina specialists developed two sequential online surveys administered to eye care professionals (ECPs). Consensus was defined as
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Concurrent Foveoschisis and Atrophy in a Patient With X-Linked Retinoschisis and Type 1 Diabetes Mellitus. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-10-01 Sandra Hoyek,Natasha F S da Cruz,Jesse Sengillo,Nimesh A Patel,Dean Eliott,Audina M Berrocal
We report the case of a 28-year-old man with X-linked retinoschisis (XLRS) and type I diabetes mellitus. The patient had bilateral foveoschisis with a tractional retinal fold in the right eye. Optical coherence tomography (OCT) revealed hyperreflective material within the inner nuclear and outer plexiform layers, photoreceptor atrophy, and retinal pigment epithelium irregularities in both eyes. Fluorescein
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RWC Update: Enhanced ILM Peeling; Retinal Gene Therapy; Laser-Induced Retinal Break and Vitreous Hemorrhage. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-10-01 Ashish Sharma,Lihteh Wu,Steven Bloom,Paulo Stanga,Joaquín Sosa Lockward,Christina Y Weng,Mohammad A Abbas,Kourous A Rezaei
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Neovascular Age-Related Macular Degeneration in a Predominantly Black Population. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-10-01 Salman J Yousuf,Jiali Ma,Luke Nelson,Michelle Chen,Terhas A Weldeslase,Oluwasegun A Akinyemi
BACKGROUND AND OBJECTIVE We intend to study the characteristics and outcomes of an understudied patient population with neovascular age-related macular degeneration (nAMD). PATIENTS AND METHODS This retrospective study evaluated presenting features and outcomes in a predominantly Black patient population with nAMD. A multivariate regression explored baseline characteristics predictive of 1-year vision
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Reply to Letter to the Editor: Endolaserless Vitrectomy With Aflibercept Monotherapy for Proliferative Diabetic Retinopathy-Related Vitreous Hemorrhage. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-10-01 Venkatkrish M Kasetty,Dennis M Marcus
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Endolaserless Vitrectomy With Aflibercept Monotherapy for Proliferative Diabetic Retinopathy-Related Vitreous Hemorrhage. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-10-01 Jesse D Sengillo,Lauren Kiryakoza,William E Smiddy,Harry W Flynn,Jayanth Sridhar
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Proliferative Diabetic Retinopathy: Enface Optical Coherence Tomography of the Vitreous. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-10-01 Samantha M A Orr,Austin Pereira,John Golding,Netan Choudhry
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ChatGPT and GPT-4 in Ophthalmology: Applications of Large Language Model Artificial Intelligence in Retina. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-10-01 Joshua Ong,Seenu M Hariprasad,Jay Chhablani
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Retinal Detachments in Pediatric Patients With X-Linked Retinoschisis: Characteristics and Surgical Outcomes. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-10-01 Jesse D Sengillo,Hasenin Al-Khersan,Landon Rohowetz,Marissa K Shoji,Hailey Robles-Holmes,Natasha Ferreira Santos da Cruz,Catherin I Negron,Nicolas A Yannuzzi,Nimesh A Patel,Audina M Berrocal
BACKGROUND AND OBJECTIVE Retinal detachments (RDs) are a complication of X-linked retinoschisis (XLRS) with a poor prognosis. This study aims to report outcomes of XLRS-RD repair in pediatric patients. MATERIALS AND METHODS The study is a retrospective analysis of pediatric patients undergoing vitreoretinal surgery for XLRS-RDs from 2000 to 2022. RESULTS Nine patients (11 eyes) met inclusion criteria
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Induction of Posterior Vitreous Detachment Using Perfluorooctane Dissection in a Pediatric Patient. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-09-01 Sandra Hoyek,Frances Wu,Audina M Berrocal,Nimesh A Patel
BACKGROUND AND OBJECTIVE Inducing a posterior vitreous detachment (PVD) may be challenging, especially in pediatric patients with firm vitreo-retinal adherence. This case report will present an alternative method of PVD induction using adjunctive perfluorooctane (PFO). MATERIALS AND METHODS An 11-year-old boy underwent scleral buckle placement and 23-gauge pars plana vitrectomy for macula-off retinal
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Nocardia Scleritis Progressing to Endophthalmitis in the Setting of Scleral Buckle Extrusion. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-09-01 Lediana Goduni,Kenneth C Fan,Diana M Laura,Joshua H Uhr,Jayanth Sridhar,Jay Chhablani
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Increase in Retinal Detachment Repair Over a Ten-Year Period at an Academic Center Compared to National Trends. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-09-01 Nikhil Bommakanti,Benjamin K Young,Thomas J Wubben,David N Zacks,Mark W Johnson
BACKGROUND AND OBJECTIVE This study aimed to determine whether cases of surgical retinal detachment (RD) repair at a tertiary care center from January 1, 2011 to December 31, 2020 increased proportionately to macular surgery cases as a control and to national trends. PATIENTS AND METHODS Current Procedural Terminology codes were used to identify cases of primary RD repair (67107, 67108), complex RD
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RWC Update: Intruding Scleral Buckle; Vitrectomy for Floaters; Group-Type Congenital Pigmented Nevi of the RPE. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-09-01 Ashish Sharma,Lihteh Wu,Steven Bloom,Paulo Stanga,Hussain Ahmad Khaqan,Gerardo Garcia-Aguirre,Joe Yuenpang Cheung,Kourous A Rezaei
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Subthreshold Micropulse Laser Acute Exudative Maculopathy in Central Serous Chorioretinopathy. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-09-01 José Ignacio Fernández-Vigo,Jacobo Enríquez-Fuentes,Carlos Oribio-Quinto,Antonio Domingo-Alarcón,Francisco Javier Moreno-Morillo
Photodynamic acute exudative maculopathy is a transient increase in subretinal fluid (SRF) within the first days after treatment in different chorioretinal diseases and tumors. Recently, this entity has attracted much attention. However, no cases of acute exudative maculopathy have been described after subthreshold laser (STL). This report presents the case of a 35-year-old male with chronic central
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Prevalence of Dome-Shaped Macula and Tilted Disc Syndrome in High Myopia. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-09-01 Jazmin Baca-Moreno,Andrée Henaine-Berra,Hillary Kimberly Osorio-Landa,David Berrones-Medina,Gerardo García-Aguirre
BACKGROUND AND OBJECTIVE Dome-shaped macula (DSM) and tilted disc syndrome (TDS) are two macular abnormalities that may occur in eyes with high myopia. The aim of this study was to determine the prevalence of both entities in our population. PATIENTS AND METHODS This was a prospective and observational study. Optical coherence tomography of the macula was performed in eyes with high myopia (spherical
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Evaluation of Inflammation in the Peripheral Multiple Sclerosis Retina Using Ultra-Widefield Optical Coherence Tomography: A Pilot Study. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-09-01 Matthew M O'Riordan,Mark T Cahill,Matthew Campbell,Hugh Kearney
BACKGROUND AND OBJECTIVE Reports of fundus fluorescein angiography (FFA) in active multiple sclerosis (MS) have shown peripheral perivenous sheathing. We sought to assess the feasibility of ultra-widefield (UWF) FFA and optical coherence tomography (OCT) in assessing the peripheral retina in MS. MATERIALS AND METHODS Participants with MS and healthy controls underwent bilateral UWF fundus photography
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Double Reverse Overlapping Scleral Trapdoor (DROST) Technique for the Removal of Juxtalenticular Intraocular Foreign Body. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-09-01 Georgios Blatsios,Nikolaos E Bechrakis
We describe the double reverse overlapping scleral trapdoor (DROST) technique, a novel minimally invasive technique for the removal of very anterior intraocular foreign bodies without the need of pars plana vitrectomy. [Ophthalmic Surg Lasers Imaging Retina 2023;54:600-602.].
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Venous Tortuosity in COL4A2-Associated Gould Syndrome. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Jin Kyun Oh,Sarah R Levi,Jose Ronaldo Lima de Carvalho,Aliaa H Abdelhakim,Michio Hirano,Irene H Maumenee,Stephen H Tsang
Mutations in collagen-encoding genes have been linked to numerous systemic diseases. Specifically, pathologic alterations in COL4A2 have been linked to Gould syndrome, a hereditary angiopathy affecting the brain, kidneys, and eyes. However, the ocular phenotype associated with COL4A2-associated disease has yet to be fully characterized. In this report, we describe a novel variant in COL4A2 identified
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Age-Related Alterations of the Macular Choroid in Healthy Eyes Assessed by Swept-Source Optical Coherence Tomography Angiography. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Aditya Verma,Kowsigan Magesan,Maanasi Mahalingam,Amose T,SriniVas R Sadda,Giulia Corradetti,Ahmed Roshdy Alagorie,Ramya Gnanaraj,Parveen Sen
OBJECTIVE To analyze age-related changes in the choroid in healthy eyes using swept-source optical coherence tomography angiography (SS-OCTA). PATIENTS AND METHODS This was a cross-sectional, prospective, observational study enrolling 222 eyes of 116 healthy participants. SS-OCTA images were captured using the PLEX Elite 9000 (Carl Zeiss Meditec) with a 6 x 6 mm pattern centered on the fovea. Subfoveal
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Lowering the Incidence of Endophthalmitis Following Intravitreal Anti-VEGF Injection: An Analysis of Aseptic Protocol Adjustment. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Ogul E Uner,Diana Lee,Remington Horesh,Brian Jewart,Christopher Seebruck
BACKGROUND AND OBJECTIVE The impact of anti-sepsis-anesthesia sequence in intravitreal injection (IVI)-associated endophthalmitis is unknown. We compared outcomes of patients who had 10% topical povidone-iodine before or after 2% topical lidocaine gel during IVIs. PATIENTS AND METHODS A retrospective study of IVIs in nine clinical sites was undertaken. Group 1 had lidocaine gel applied first. This
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Vitreous Hemorrhage in Pediatric Patients With X-Linked Retinoschisis: Characteristics and Outcomes. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Natasha F S da Cruz,Jesse D Sengillo,Hasenin Al-Khersan,Catherin I Negron,Marley B Felder,Nimesh A Patel,Audina M Berrocal
OBJECTIVE To report the management and outcomes of vitreous hemorrhage in pediatric patients with X-linked retinoschisis (XLRS). MATERIALS AND METHODS Retrospective case series of pediatric patients with XLRS with vitreous hemorrhage between January 2000 and January 2022 at the Bascom Palmer Eye Institute. RESULTS Nine patients (12 eyes) met inclusion criteria. The average age at presentation was 5
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The Incidence, Time to Development, and Risk Factors for Fellow Eye Retinal Vein Occlusions. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Brian J Liu,Jacqueline K Shaia,Kevin Allan,Blanche L Kuo,Rishi P Singh,Katherine E Talcott
BACKGROUND AND OBJECTIVE Little is known about factors affecting risk or time to development of fellow eye retinal vein occlusion (RVO). The purpose of this study was to examine the incidence and risk factors for fellow eye RVO. PATIENTS AND METHODS This was a retrospective case-control study comparing unilateral and fellow eye RVO patients. This study was exempt by the Cleveland Clinic Institutional
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RWC Update: Subretinal Cysticercosis; Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy; Waardenburg Syndrome With Pseudo-Choroidal Melanocytosis. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Ashish Sharma,Lihteh Wu,Steven Bloom,Paulo Stanga,Marcio B Nehemy,Diva Kant Misra,María H Berrocal,Luis Acaba-Berrocal,Gil Calvão-Santos,Keissy Sousa,Kourous A Rezaei
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Immunological and Inflammatory Side Effects of Treatments for Age-Related Macular Degeneration. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 TsunKang Chiang,Shree K Kurup,Seenu M Hariprasad
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Macular Thickness Fluctuations in Eyes With Diabetic Macular Edema Treated With Intravitreal Steroid. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Vivian D Roan,Blanche L Kuo,Brian J Liu,Carolina C S Valentim,Rishi P Singh
BACKGROUND AND OBJECTIVE Macular thickness fluctuations (MTF) over time may be more predictive of visual outcomes than absolute macular thickness in patients with diabetic macular edema (DME) treated with anti-vascular endothelial growth factor (anti-VEGF). It is unclear whether this association exists in DME patients treated with intravitreal steroids or whether steroids confer reduced MTF versus
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Vogt-Kayanagi-Harada-Like Uveitis Induced by Dabrafenib/Trametinib Therapy for Cutaneous Malignant Melanoma. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Nilufer Zorlutuna Kaymak,Aysin Tuba Kaplan
A 54-year-old woman with cutaneous malignant melanoma developed Vogt-Kayanagi-Harada (VKH)-like uveitis induced by dabrafenib/trametinib therapy. Dabrafenib was discontinued but she continued to use trametinib due to the risk of disease progression. Intraocular inflammation resolved after cessation of dabrafenib and administration of topical and systemic corticosteroids. Our patient outlines the importance
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Repair of a Tractional Retinal Detachment in the Setting of an Idiopathic Vasoproliferative Tumor. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Jennifer O Adeghate,Samantha R Goldburg,Brian Marr,Alan Sheyman,Jules Winokur,Talia R Kaden
Vasoproliferative tumors (VPT) are benign retinal lesions that may cause epiretinal membrane proliferation and tractional retinal detachments (TRD). We describe a case of a 71-year-old woman who presented with a macula involving TRD in the setting of a VPT. Given the limited number of publications on the management of these cases, we aim to articulate some principles we believe may be helpful in planning
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Evaluation of Automated Measurement of Macular Ischemic Changes in Retinal Vein Occlusion With Optical Coherence Tomography Angiography. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Jens U Werner,Jens Dreyhaupt,Christian Enders
OBJECTIVE The foveal avascular zone (FAZ) is altered in patients with retinal vein occlusion (RVO) and correlates inversely with visual acuity. Optical coherence tomography angiography (OCTA) is an imaging tool to visualize FAZ safely and easily. Automated measurements can facilitate interpretation of OCTA images. In this comparative cross-sectional study, we compare the results of manual measurement
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Myopic Traction Maculopathy in Low Myopia. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Emily D Cole,Mark W Johnson
We describe a case of myopic traction maculopathy (MTM) in a patient with low myopia that resolved with surgical intervention. Our patient demonstrated no other features of myopic degeneration and none of the typical tractional elements that cause MTM, such as vitreomacular traction due to partial posterior vitreous detachment (PVD) with vitreomacular adhesion, epiretinal membrane, or a remnant cortical
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Industry Collaborations: What Is the Role of the University-Based Ophthalmologist? Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-08-01 Avni P Finn,Caroline Baumal
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RWC Update: Segmental Scleral Buckling; Complement Inhibition in Geographic Atrophy; Tattoo-Induced Uveitis. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-07-01 Ashish Sharma,Lihteh Wu,Steven Bloom,Paulo Stanga,Ahmed Sallam,Jerónimo Villa-Piñeros,Francisco J Rodríguez,Natasa Draca,Ratko Lazic,Kourous A Rezaei
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Quantitative Evaluation of Progression of Retinal Vascularization After 60 Weeks Postmenstrual Age in Infants Treated With Bevacizumab. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Sadık Etka Bayramoğlu,Nihat Sayin
BACKGROUND AND OBJECTIVE To investigate the progression of retinal vascularization after 60 weeks postmenstrual age (PMA) in eyes treated with intravitreal bevacizumab (IVB). PATIENTS AND METHODS Twenty-seven eyes that were treated with IVB and underwent two consecutive fluorescein angiographies (FA) after 60 weeks PMA. Horizontal disc diameter (DD), disc-to-fovea (DF) distance, and length of temporal
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Rapid Improvement in Lipid Maculopathy Following Faricimab Therapy in Recalcitrant Familial Exudative Vitreoretinopathy. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Hashem H Ghoraba,Charles DeBoer,Darius M Moshfeghi
A monocular 22-year-old man with recalcitrant familial exudative vitreoretinopathy presented with progressive subretinal lipid exudation and lipid maculopathy that responded poorly to repeated aflibercept injections. The subretinal exudation started temporally and gradually progressed, involving the macula and the retinal periphery in all 4 quadrants. At the 22-month follow-up visit, macular and peripheral
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A Review of Novel Anesthetic Technique for Vitreoretinal Surgery. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Steven Dodson,Rui Wang,Bozho Todorich
BACKGROUND AND OBJECTIVE Currently, there is no standardized formulation of intravenous anesthetic that exists for vitreoretinal surgery. We describe a novel anesthetic protocol for vitreoretinal surgery that is safe and effective for patients and surgeons alike. STUDY DESIGN Review the current challenges to vitreoretinal anesthetic technique and descriptive overview outlining the proposed anesthetic
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The Impact of Social Determinants of Health on Presentation, Treatment, and Outcomes in Branch Retinal Vein Occlusion With Cystoid Macular Edema. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Anania G Woldetensaye,Jenna M Selander,Harrison Huang,Palak V Patel,Alex Villarreal,Richard A Hesse,Margaret A Greven
BACKGROUND AND OBJECTIVE To investigate the impact of social determinants of health on the presentation, treatment, and outcomes of branch retinal vein occlusion (BRVO) with cystoid macular edema (CME). PATIENTS AND METHODS A retrospective chart review was conducted of patients with BRVO and CME treated with anti-vascular endothelial growth factor (anti-VEGF) injections at Atrium Health Wake Forest
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New Imaging Technology for Simultaneous Multiwavelength-UWF Fundus Fluorescein Angiography and Indocyanine Green Angiography With Navigated Central and Peripheral SS-OCT. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Francisco Javier Valentin Bravo,William Ayliffe,Sebastian Francis Eduardo Stanga,Ursula Inge Reinstein,Rob Moxham,Zeb Tariq,Susan M Downes,Paulo Eduardo Stanga
OBJECTIVE Our aim was to assess central and peripheral retinal and choroidal diseases using novel simultaneous multiwavelength-ultra-widefield (MW-UWF) fundus fluorescein angiography (FFA)/indocyanine green angiography (ICGA) with navigated central and peripheral swept-source optical coherence tomography (SS-OCT) technology. METHODS Retrospective evaluation was carried out of 30 consecutive patients
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Clinical Factors and Outcomes of Acute-Onset Endophthalmitis Following Small-Gauge Pars Plana Vitrectomy Surgery. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Tommaso Vagaggini,Olufemi E Adams,Christian D Curran,Michael L Prairie,Mikayla J Baker,Ananth Sastry,Edwin H Ryan,D Wilkin Parke,Robert A Mittra,Peter H Tang
BACKGROUND AND OBJECTIVES Describe risk factors, findings, and outcomes of acute endophthalmitis (AE) following small-gauge pars plana vitrectomy (PPV). PATIENTS AND METHODS This was a retrospective single-center, nonrandomized study of post-PPV AE patients from 2013 to 2021. All received vitreous biopsy before treatment. Patients were divided into cohorts: 1) PPV within 3 days of diagnosis (Urgent-PPV)
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Incidental Unilateral Macular Lesions in Children. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Miriam Ehrenberg,Orly Gal Or,Ronit Friling,Yair Pesoa,Gad Dotan,Amir Sternfeld
BACKGROUND This study aims to examine the rare entity of unilateral macular lesions in the pediatric population and describe the distinct diagnoses and characterizations related to these findings. METHODS A retrospective cohort design. The database of the ophthalmology clinic in a tertiary medical center was reviewed to identify all children with incidental unilateral macular findings, examined during
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Multimodal Imaging Study of Patients With Vitamin A Deficiency Retinopathy. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Francesco Pichi,Shaikha Aljneibi,Piergiorgio Neri,Pukhraj Rishi,Maria Vittoria Cicinelli,Ugo Introini,Sumit Sharma,Marion R Munk,Sirichai Pasadhika,Julio J Gonzalez-Lopez,Andrea Lembo,Paolo Nucci,Netan Choudhry,Ester Carreño
OBJECTIVES To describe multimodal imaging findings of vitamin A deficiency retinopathy. METHODS A retrospective study of patients with serum retinol < 0.3 mg/L. Fundus color photos, spectral domain-optical coherence tomography (SD-OCT), and fundus autofluorescence (FAF) were reviewed and, when available, electrophysiological tests were analyzed. RESULTS Forty-five eyes (63.9 ± 15.7 years) were included
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RWC Update: Vitrectomy Surgery in a Pre-Phthisical Eye; Update on the Surgical Management of Macular Holes: The Inverted ILM Flap Technique and How It Revolutionized Macular Hole Surgery; Retinal Arteriovenous Malformation. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Ashish Sharma,Lihteh Wu,Steven Bloom,Paulo Stanga,Marcio B Nehemy,Carlos E Veloso,Zofi A Anna Nawrocka,Jerzy Nawrocki,Şengül Özdek,Ece Özdemir Zeydanlı,Kourous A Rezaei
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Risk Factors for the Development of Fellow Eye Horseshoe Retinal Tears Following Horseshoe Retinal Tear in the Presenting Eye. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Enoch T Peng,Matthew N Parvus,Hannah J Yu,Stephen M Laswell,William A Pearce,Kenneth C Fan,James C Major,David M Brown,Charles C Wykoff,Sagar B Patel
BACKGROUND This study investigated factors associated with fellow eye horseshoe retinal tear (HST) development in consecutive patients with a presenting eye HST. MATERIALS AND METHODS Medical records were reviewed for patients with initial HSTs between 2015 and 2017 and 24 factors were analyzed. Logistic regression was used to assess factors associated with fellow eye HST development. RESULTS In total
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Near-Complete Drusen Resolution With Brolucizumab: A Mechanism for Proinflammatory Mediated Drusen Clearance? Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Matthew O'Riordan,Natalie Hudson,Jeffrey O'Callaghan,Matthew Campbell,Mark Cahill
A 68-year-old woman with macular drusen was diagnosed with neovascular age-related macular degeneration (AMD) and treated with intravitreal brolucizumab. She had a good response to treatment with reduced height of the pigment epithelial detachment, and a good visual outcome. Remarkably, she had a near-complete resolution of macular drusen, yet this was accompanied by the development of anterior uveitis
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Gender and Research Productivity of Vitreoretinal Surgery Fellowship Program Directors. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 John C Lin,Anagha Lokhande,Ingrid U Scott,Paul B Greenberg
BACKGROUND AND OBJECTIVE Characteristics of vitreoretinal surgery fellowship program directors (PDs) in North America are not well described. This study reports on the gender and research productivity of vitreoretinal surgery PDs in the United States and Canada. MATERIALS AND METHODS We reviewed demographics, total number of Scopus-indexed publications, h-index, and m-quotient for vitreoretinal surgery
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Progression of Pentosan-Polysulfate Sodium-Associated Retinopathy: Intermediate Follow-Up. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Ella H Leung,Ana Levie-Sprick,Sahana Sharma,Gregory D Lee,Hyung Cho,David Chin Yee,Krishna Mukkamala
BACKGROUND AND OBJECTIVE To compare the risk factors for the development and progression of pigmentary retinopathy in patients exposed to pentosan polysulfate sodium (PPS). MATERIALS AND METHODS Retrospective cohort study of patients exposed to PPS with at least two follow-up visits with multimodal imaging. RESULTS A total of 97 patients were included (33 with PPS-associated retinopathy and 64 without)
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Utilization of Crowdfunding for Medical Expenses Related to Vitrectomy. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-06-01 Urvi Gupta,Madhukar Kumar,Anna K Wu,Rishi P Singh
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Visualization of Changes in Retinal Vascular Resistance Before and After Administration of Anti-Vascular Endothelial Growth Factor for Branch Retinal Vein Occlusion. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-05-01 Ryo Tomita,Takeshi Iwase
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Macular Hole Closure With Intravitreal Dexamethasone Implant. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-05-01 Arsalan A Ali,Ashkan M Abbey
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New Terminology and Methodology for the Assessment of the Vitreous, Its Floaters and Opacities, and Their Effect on Vision: Standardized and Kinetic Anatomical and Functional Testing of Vitreous Floaters and Opacities (SK VFO Test). Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-05-01 Paulo Eduardo Stanga,Francisco Javier Valentin Bravo,Ursula Inge Reinstein,Sebastian Francis Eduardo Stanga,John Marshall,Timothy J Archer,Dan Z Reinstein
OBJECTIVE To introduce VFO and SK VFO Test: new, more representative terminology for symptoms of vitreous floaters/opacities (VFO) and new standardized kinetic (SK) anatomical-functional assessment. MATERIALS AND METHODS Eight eyes underwent before-after limited vitrectomy (LV): best-corrected visual acuity, low-luminance visual acuity, Minnesota Low Vision Reading Chart near visual acuity in logMAR
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Hyperreflective Vasculature: A Negative Prognostic Sign for Retinal Vein Occlusion on Near-Infrared Reflectance Imaging. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-05-01 Saena Arifeen Sadiq,Shubhendu Mishra,Rukhsana G Mirza
BACKGROUND AND OBJECTIVE To investigate the clinical significance of hyperreflective vasculature visualized on near-infrared reflectance (NIR) in patients with retinal vein occlusion (RVO). METHODS In this retrospective study, RVO patients with NIR imaging and at least 1-year follow-up, and without confounding disease, were included. Two blinded independent graders identified vascular hyperreflectivity
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RWC Update: Intraoperative Fluorescein Angiography, Plasma Rich in Growth Factor as Adjuvant to Vitrectomy in High Myopic Retinal Detachment Associated With Full-Thickness Macular Hole, Giant Tear of the Retinal Pigment Epithelium. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-05-01 Ashish Sharma,Lihteh Wu,Steven Bloom,Paulo Stanga,Marta S Figueroa,Andrea Govetto,Anjana Mirajkar,Manish Nagpal,Navneet Mehrotra,Akansha Sharma,Kourous A Rezaei
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Dose-Dependent and Reversible Serous Retinal Detachments in Fibroblast Growth Factor Receptor Inhibitor-Associated Retinopathy. Ophthalmic Surg. Lasers Imaging Retina (IF 1.0) Pub Date : 2023-01-05 Deep Parikh,Veshesh Patel,Nicolas Yannuzzi,Scott H Greenstein,Dean Eliott,Leo A Kim
We report two cases of fibroblast growth factor receptor (FGFR) inhibitor-associated retinopathy, including the first case of Debio 1347 associated retinopathy manifesting with bilateral serous retinal detachments along the superotemporal arcades and a case of erdafitinib associated retinopathy manifesting with classic foveal serous retinal detachments. Both cases demonstrate a clear dose-dependent