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Neuroimaging the Development of Olfactory Function in a Woman With No Olfactory Bulbs. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-30 Vanda Faria,Akshita Joshi,Coralie Mignot,Divesh Thaploo,Susanne Weise,Thomas Hummel
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Hypoglossal Nerve Stimulation and Cardiovascular Outcomes for Patients With Obstructive Sleep Apnea: A Randomized Clinical Trial. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-30 Raj C Dedhia,Donald L Bliwise,Arshed A Quyyumi,Erica R Thaler,Maurits S Boon,Colin T Huntley,Everett G Seay,Akshay Tangutur,Patrick J Strollo,Nil Gurel,Brendan T Keenan
Importance Sham-controlled trials are needed to characterize the effect of hypoglossal nerve stimulation (HGNS) therapy on cardiovascular end points in patients with moderate-severe obstructive sleep apnea (OSA). Objective To determine the effect of therapeutic levels of HGNS, compared to sham levels, on blood pressure, sympathetic activity, and vascular function. Design, Setting, and Participants
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Pulmonary and Clinical Outcomes After Bilateral Submandibular Gland Excision and Parotid Duct Ligation for Refractory Sialorrhea. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-22 Ashley L Miller,Erik B Hysinger,Meredith E Tabangin,Cherie Torres-Silva,Alessandro de Alarcon,Catherine K Hart
Importance Refractory sialorrhea in children can result in pulmonary aspiration and irreversible lung damage. Despite many studies devoted to the surgical treatment of sialorrhea, there is a paucity of objective outcome measures after surgery, especially with regard to pulmonary health. Objectives To assess whether bilateral submandibular gland excision and bilateral parotid duct ligation ("DROOL"
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In-Home Smartphone-Based Prediction of Obstructive Sleep Apnea in Conjunction With Level 2 Home Polysomnography. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-16 Seung Cheol Han,Daewoo Kim,Chae-Seo Rhee,Sung-Woo Cho,Vu Linh Le,Eun Sung Cho,Hyunggug Kim,In-Young Yoon,Hyeryung Jang,Joonki Hong,Dongheon Lee,Jeong-Whun Kim
Importance Consumer-level sleep analysis technologies have the potential to revolutionize the screening for obstructive sleep apnea (OSA). However, assessment of OSA prediction models based on in-home recording data is usually performed concurrently with level 1 in-laboratory polysomnography (PSG). Establishing the predictability of OSA using sound data recorded from smartphones based on level 2 PSG
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Predictability of Olfactory Neuroblastoma Staging Systems-Reply. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-16 Garret Choby,Jamie O'Byrne
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Predictability of Olfactory Neuroblastoma Staging Systems. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-16 Ryan Sun,Tyler M Seibert,Lee-Jen Wei
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Tender Cervical Lymphadenopathy in a Pediatric Patient. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-16 Morgan P Brown,Andrew R Scott
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Partial Thyroidectomy With Incidental Metastatic Lymph Nodes. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-16 Ehab Alameer,Alana Eagan,Daniel W Scholfield,Robbie S R Woods,R Michael Tuttle,Richard J Wong,Snehal G Patel,Ian Ganly
Importance The need for completion thyroidectomy in patients with incidental metastatic lymph nodes after partial thyroidectomy is unclear. Objective To investigate the outcomes of patients with incidental metastatic lymph nodes following partial thyroidectomy. Design, Setting, and Participants A retrospective review of a prospectively maintained thyroid cancer database from 1985 to 2015 was carried
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Liquid Biopsies for Head and Neck Cancers-Any Hope for Human Papillomavirus-Negative Disease?-Reply. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-16 Rocco M Ferrandino,Marshall R Posner,Scott A Roof
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Olfactory and Gustatory Function 3 Years After Mild COVID-19-A Cohort Psychophysical Study. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-09 Paolo Boscolo-Rizzo,Thomas Hummel,Giacomo Spinato,Luigi Angelo Vaira,Anna Menini,Claire Hopkins,Giancarlo Tirelli
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Risk of Carcinoma in Pleomorphic Adenomas of the Parotid. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-01 Helena Levyn,Tejas Subramanian,Alana Eagan,Nora Katabi,Oscar Lin,NatalieDeana Dizon Badillo,German Martinez,Daniel W Scholfield,Richard J Wong,Jatin P Shah,Babak Givi,Luc G T Morris,Ian Ganly,Snehal G Patel
Importance Surgery is the mainstay of treatment for pleomorphic adenomas (PAs) of the parotid to prevent further growth and potential future malignant transformation. While historical case series have reported transformation rates as high as 10%, there is a lack of contemporary methodologically sound data. Objective To examine the rate of carcinoma ex pleomorphic adenoma (CXPA) detection in untreated
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Oncologic Outcome in Advanced Oral Squamous Cell Carcinoma After Refusal of Recommended Adjuvant Therapy. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-01 Friedrich Mrosk,Christian Doll,Julia Scheer,Felix Neumann,Elena Hofmann,Kilian Kreutzer,Jan Voss,Kerstin Rubarth,Marcus Beck,Max Heiland,Steffen Koerdt
Importance Clinicians may be confronted with patients refusing recommended adjuvant therapy (AT) after the primary resection of an advanced oral squamous cell carcinoma (OSCC). However, for this tumor entity, data are lacking regarding the oncological outcomes and associated factors after refusal of AT. Objective To evaluate the difference in survival and disease recurrence for patients with and without
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Methods, Detection Rates, and Survival Outcomes of Screening for Head and Neck Cancers: A Systematic Review. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-01 Edward A Sykes,Natalie Weisbrod,Ella Rival,Aminul Haque,Rui Fu,Antoine Eskander
Importance Head and neck cancers (HNCs) are often diagnosed at advanced clinical stages during their symptomatic phase, leading to a reduced treatment window and poor survival. Screening programs have been suggested as a mitigation strategy. Objective To examine the effectiveness of current HNC screening programs in improving diagnosis and survival in adults. Evidence Review This Preferred Reporting
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Team-Based Surgical Approach to Head and Neck Microvascular Free Flap Reconstruction. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-01 Pratyusha Yalamanchi,Nithin S Peddireddy,Brennan McMichael,Charles Keilin,Keith A Casper,Kelly M Malloy,Jeffrey S Moyer,Mark E P Prince,Andrew J Rosko,Chaz L Stucken,Matthew E Spector,Steven B Chinn
Importance Because microvascular free flap reconstruction is increasingly used to restore function in patients with head and neck cancer, there is a growing need for evidence-based perioperative care. Objective To assess the association of different team-based surgical approaches with intraoperative and postoperative outcomes for patients undergoing head and neck free flap reconstruction. Design, Setting
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Selective Deep Lobe Parotidectomy vs Total Parotidectomy for Patients With Benign Deep Lobe Parotid Tumors. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-01 Katherine P Wallerius,Katherine Z Xie,Lauren Y Lu,Christine M Lohse,Linda X Yin,Daniel L Price,Kathryn M Van Abel,Eric J Moore
Importance Limited literature exists on surgical outcomes after selective deep lobe parotidectomy (SDLP) with preservation of superficial lobe for patients with benign deep lobe tumors. Objective To compare the following factors for SDLP vs total parotidectomy for patients with benign tumors in the deep lobe: postoperative complications, including facial nerve paresis or paralysis, Frey syndrome, first
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Margin Assessment Methods in Oral Cavity Squamous Cell Carcinoma and Recurrence: Tumor Bed vs Resection Specimen Sampling. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-01 Shannon S Wu,Neil Woody,Jennifer Hesse,Samantha Cook,Vincent Cracolici,Jamie A Ku,Brandon Prendes,Natalie Silver,Joseph Scharpf,Philip R Brauer,Chandana A Reddy,Shauna R Campbell,Shlomo A Koyfman,Brian Burkey,Eric D Lamarre
Importance Positive margins and margin clearance are risk factors for recurrence in oral cavity squamous cell carcinoma (OCSCC), and these features are used to guide decisions regarding adjuvant radiation treatment. However, the prognostic value of intraoperative tumor bed vs resection specimen sampling is not well defined. Objective To determine the prognostic implications of intraoperative margin
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Head and Neck Surgery-The Call to Joyful Sacrificial Giving. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-01 Brian B Burkey
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Demographic and Academic Productivity Trends Among American Head & Neck Society Fellows Over a 20-Year Period. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-11-01 Hilary C McCrary,Molly Meeker,Janice L Farlow,Nolan B Seim,Matthew O Old,Enver Ozer,Amit Agrawal,James W Rocco,Stephen Y Kang,Carol R Bradford,Catherine T Haring
Importance Historical data reveal that, compared with women, men are more likely to pursue a head and neck surgical oncology fellowship, but little is known about possible gender differences in academic productivity. Objective To assess demographic trends and academic productivity among American Head & Neck Society (AHNS) fellowship graduates. Design, Setting, and Participants This cross-sectional
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Malnutrition and Adverse Outcomes After Surgery for Head and Neck Cancer. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-26 William T Reed,Rong Jiang,Tetsu Ohnuma,Russel R Kahmke,Shreyas Pyati,Vijay Krishnamoorthy,Karthik Raghunathan,Nosayaba Osazuwa-Peters
Importance Patients with head and neck cancer (HNC) have an increased risk of malnutrition, partly due to disease location and treatment sequelae. Although malnutrition is associated with adverse outcomes, there is little data on the extent of outcomes and the sociodemographic factors associated with malnutrition in patients with HNC. Objectives To investigate the association of race, ethnicity, and
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Pediatric Patient With Persistent Postoperative Fevers After Esophageal Foreign Body Removal. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-26 Raihanah Alsayegh,Thomas Hudson,Joshua Gurberg
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Dental Extractions Before Radiation Therapy and the Risk of Osteoradionecrosis in Patients With Head and Neck Cancer. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-19 Junhyung Lee,Katrina Hueniken,Karl Cuddy,Jiajie Pu,Amr El Maghrabi,Andrew Hope,Ali Hosni,Michael Glogauer,Erin Watson
Importance Patients with head and neck cancer undergo extraction of teeth with poor prognoses to minimize post-radiation therapy (RT) extractions, which are known to cause osteoradionecrosis (ORN). However, many patients are required to start RT before the extraction sites are completely healed. The role of pre-RT extractions in the development of ORN has been disputed in literature. Objective To determine
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Promoting Surgeon-Scientists in Otolaryngology-Head and Neck Surgery-From Bench to Bedside. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-19 Nikitha Kosaraju,Donald P Keating,Grace S Kim,Lindsay S Moore,Konstantina M Stankovic
Importance Surgeon-scientists (defined as principal investigators [PIs] with a Doctor of Medicine [MD] degree or a combined MD and Doctor of Philosophy [PhD] degree) in otolaryngology-head and neck surgery (OHNS) are imperative for achieving clinical translation in the OHNS field. Objective To (1) raise awareness about the current state of surgeon-scientists in OHNS, (2) contextualize the landscape
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A Rare Case of Idiopathic Lymphadenopathy. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-19 Lexi Goehring,Joy King,Jordan Pleitz
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Improved Cochlear Implant Performance Estimation Using Tonotopic-Based Electrocochleography. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-19 Amit Walia,Matthew A Shew,Jordan Varghese,Patrick Ioerger,Shannon M Lefler,Amanda J Ortmann,Jacques A Herzog,Craig A Buchman
Importance Cochlear implantation produces remarkable results in postlingual deafness, although auditory outcomes vary. Electrocochleography (ECochG) has emerged as a valuable tool for assessing the cochlear-neural substrate and evaluating patient prognosis. Objective To assess whether ECochG-total response (ECochG-TR) recorded at the best-frequency electrode (BF-ECochG-TR) correlates more strongly
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Fiscal Irresponsibility Is a Public Health Threat. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-06 Jay F Piccirillo
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Rising Medical Complexity of Tracheotomy Placement in the Otolaryngology Department. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-05 Alexander Gelbard
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Subjective and Objective Hearing Loss Among US Adult Cancer Survivors. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-05 Qian Wang,Changchuan Jiang,Chi Wen,Hui Xie,Yannan Li,Yaning Zhang,Leila J Mady,Debora S Bruno,Giselle M A Dutcher,Lauren S Chiec,Afshin Dowlati,Melinda L Hsu
Importance Cancer survivors are at a higher risk of developing hearing loss (HL) due to older age, chemotherapy, and radiotherapy. However, the prevalence of HL among US cancer survivors remains unknown. Additionally, there is a lack of uniform HL screening guidelines for this enlarging population. Objective To estimate the prevalence of subjective HL and objective HL by audiometry test among cancer
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Factors Associated With Otolaryngologists Performing Tracheotomy. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-05 Shady I Soliman,Bharat Akhanda Panuganti,David O Francis,John Pang,Dasha Klebaner,Alicia Asturias,Ali Alattar,Samuel Wood,Morgan Terry,Paul C Bryson,Courtney B Tipton,Elise E Zhao,Ashli O'Rourke,Chloe Santa Maria,David R Grimm,C Kwang Sung,Wilson P Lao,Jordan M Thompson,Brianna K Crawley,Sarah Rosen,Anna Berezovsky,Robbi Kupfer,Theresa B Hennesy,Matthew Clary,Ian T Joseph,Kamron Sarhadi,Maggie Kuhn
Importance Tracheotomies are frequently performed by nonotolaryngology services. The factors that determine which specialty performs the procedure are not defined in the literature but may be influenced by tracheotomy approach (open vs percutaneous) and other clinicodemographic factors. Objective To evaluate demographic and clinical characteristics associated with tracheotomies performed by otolaryngologists
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The Global Otolaryngology-Head and Neck Surgery Workforce. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-01 Beatriz Petrucci,Samuel Okerosi,Rolvix H Patterson,Sara B Hobday,Valerie Salano,Christopher J Waterworth,Robert M Brody,Holly Sprow,Blake C Alkire,Johannes J Fagan,Sharon Ovnat Tamir,Carolina Der,Mahmood F Bhutta,Ivy W Maina,Jonathan C Pang,Davina Daudu,Allan G Mukuzi,Tarika Srinivasan,Carolina A Pietrobon,Sheng-Po Hao,Doreen Nakku,Amina Seguya,Taseer F Din,Olga Djoutsop Mbougo,Lilian W Mokoh,Farizeh
Importance A core component of delivering care of head and neck diseases is an adequate workforce. The World Health Organization report, Multi-Country Assessment of National Capacity to Provide Hearing Care, captured primary workforce estimates from 68 member states in 2012, noting that response rates were a limitation and that updated more comprehensive data are needed. Objective To establish comprehensive
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Socioeconomic Status Among Cochlear Implant Candidates and Association With Surgical Pursuance. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-01 Alexandra E Quimby,Sanjena Venkatesh,Martin Corsten,James Ted McDonald,Tiffany P Hwa,Douglas C Bigelow,Michael J Ruckenstein,Stephanie Johnson-Obaseki,Jason A Brant
Importance Despite the sizeable global burden of hearing loss, cochlear implants have poor penetrance among eligible hearing-impaired individuals. Identifying populations who may benefit from a cochlear implant but among whom penetrance is poor is an important aim in reducing the health-related and economic effects of hearing loss on both individuals and society. Objectives To explore the association
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Messaging Clearly and Effectively About Hearing Loss and Increased Dementia Risk. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-01 Jan Blustein,Barbara E Weinstein,Joshua Chodosh
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The Risks and Repercussions of Poor Oral Health Among Immigrants. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-10-01 Nazineen Kandahari,Nilufar Kayhani,Zainab Farzal
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Virtual Tumor Board to Foster Interinstitutional Head and Neck Cancer Subspecialty Care. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-28 Tony K W Hung,Daphna Y Gelblum,Clinton A Kuwada,Akshay V Patel,Andrew Salner,David G Pfister,Jennifer R Cracchiolo
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Omission of Copyright Notice for Questionnaire in Supplement. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-21
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Efficacy of Gabapentin For Post-COVID-19 Olfactory Dysfunction: The GRACE Randomized Clinical Trial. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-21 Ashna Mahadev,Firas Hentati,Brevin Miller,James Bao,Amber Perrin,Dorina Kallogjeri,Jay F Piccirillo
Importance The COVID-19 pandemic affected millions of people and has become a dominant etiology of olfactory dysfunction (OD). No interventions with definitive clinical utility exist. Gabapentin represents a potential therapy for COVID-19-induced OD. Objective To evaluate the efficacy of oral gabapentin on olfactory function and olfaction-related quality of life in patients with COVID-19-induced OD
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Use of Physical Therapy and Subsequent Falls Among Patients With Dizziness in the US. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-14 Schelomo Marmor,Pinar Karaca-Mandic,Meredith E Adams
Importance Among adults who present for clinical evaluation of dizziness, there is a critical need to identify interventions, such as physical therapy (PT), to mitigate the risk of falls over time. Objective The primary objective was to examine the association between receipt of PT and falls requiring medical care within 12 months of presentation for dizziness. Secondary objectives included identification
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Hearing Impairment and School Engagement Outcomes in US Children. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-14 Inderpreet Kaur Khalsa,Dylan K Chan
Importance Ensuring appropriate school engagement for deaf or hard of hearing (DHH) children in the US is important for improving their long-term outcomes as they grow into adults. Objective To examine the associations between hearing loss (HL), its sequelae (speech and/or language disorders, behavioral and/or conduct problems, and neuropsychiatric and/or learning disorders), and various school engagement
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Elexacaftor-Tezacaftor-Ivacaftor Therapy for Chronic Sinus Disease in Cystic Fibrosis. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-07 Shahid Sheikh,Mai-Lan Ho,Mariah Eisner,Courtney Gushue,Grace Paul,Melissa Holtzlander,Terri Johnson,Karen S McCoy,Meredith Lind
Importance Cystic fibrosis (CF) is a multiorgan genetic disease with progressive upper and lower airway involvement. The effects of CF transmembrane conductance regulator (CFTR) modifier therapies on CF-related upper airway disease, specifically chronic rhinosinusitis (CRS), are not characterized. Objective To determine the outcome of elexacaftor-tezacaftor-ivacaftor (ETI) on CRS as measured by changes
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Single-Case Experimental Designs and N-of-1 Trials-An Alternative to Randomized Clinical Trials for Clinical Research in Otorhinolaryngology. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Soumia Taoui,Benoît Lepage,Mathieu Marx
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Multicenter Survival Analysis and Application of an Olfactory Neuroblastoma Staging Modification Incorporating Hyams Grade. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Garret Choby,Mathew Geltzeiler,Joao Paulo Almeida,Pierre-Olivier Champagne,Erik Chan,Jeremy Ciporen,Mark B Chaskes,Juan Fernandez-Miranda,Paul Gardner,Peter Hwang,Keven Seung Yong Ji,Aristotelis Kalyvas,Keonho A Kong,Ryan McMillan,Jayakar Nayak,Jamie O'Byrne,Chirag Patel,Zara Patel,Maria Peris Celda,Carlos Pinheiro-Neto,Olabisi Sanusi,Carl Snyderman,Brian D Thorp,Jamie J Van Gompel,Sarah C Young,Georgios
Importance Current olfactory neuroblastoma (ONB) staging systems inadequately delineate locally advanced tumors, do not incorporate tumor grade, and poorly estimate survival and recurrence. Objective The primary aims of this study were to (1) examine the clinical covariates associated with survival and recurrence of ONB in a modern-era multicenter cohort and (2) incorporate Hyams tumor grade into existing
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Outcomes of Treatment With Neoadjuvant Cemiplimab for Patients With Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck: Secondary Analysis of a Phase 2 Clinical Trial. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Renata Ferrarotto,Priyadharsini Nagarajan,Jacob M Maronge,Jason M Johnson,David I Rosenthal,Jeffrey N Myers,Neil D Gross
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Setting the Stage for Olfactory Neuroblastoma. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Charles A Riley,Nathan Yang,David A Gudis
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Omission of Sources for 2 Questions in Survey Instrument. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Jasleen Singh,Sumit Dhar
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Oral Human Papillomavirus Prevalence and Genotyping Among a Healthy Adult Population in the US. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Anna R Giuliano,Marisa Felsher,Tim Waterboer,Haïtham Mirghani,Hisham Mehanna,Craig Roberts,Ya-Ting Chen,Mark Lynam,Montse Pedrós,Emilio Sanchez,Bradley Sirak,Shikha Surati,Laia Alemany,Edith Morais,Miquel Angel Pavón
Importance In the US, oropharyngeal cancer, predominantly caused by high-risk (HR) human papillomavirus (HPV) infection, is the most frequent HPV-associated cancer, surpassing cervical cancer. However, little is known about oral HPV prevalence and genotype distribution in the general population. Objective To assess oral HPV prevalence and factors associated with HR and low-risk infection in a general
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Exploring Olfactory Dysfunction as a Marker of Frailty and Postoperative Outcomes in Head and Neck Cancer. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Leila J Mady,Emma De Ravin,Varun Vohra,Joseph Lu,Jason G Newman,Daniel E Hall,Pamela H Dalton,Nicholas R Rowan
Importance Olfactory dysfunction (OD) is increasingly recognized as a robust marker of frailty and mortality. Despite broad recognition of frailty as a critical component of head and neck cancer (HNC) care, there is no standardized frailty assessment. Objective To assess the prevalence of OD and its association with frailty and postoperative outcomes in HNC. Design, Setting, and Participants In this
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Lead Time to Recurrence After Posttreatment Plasma and Saliva HPV DNA Testing in Patients With Low-Risk HPV Oropharynx Cancer. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Joseph Califano,Andrew Yousef,Heba Mostafa,Alexandra Valsamakis,Xinlian Zhang,Nikolaos Batis,Christy Varghese,Joanna Parish,Michael Forman,Junko Jarrett,Karen Messer,Hisham Mehanna
Importance Head and neck squamous cell carcinoma is a highly lethal cancer that is often associated with human papillomavirus (HPV). Recent studies have shown promise in the use of HPV DNA detection in salivary rinses and plasma as a factor associated with a future diagnosis of HPV-positive oropharynx cancer (HPVOPC). However, the use of plasma and salivary HPV DNA detection in defining risk for recurrence
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The Role of Ear, Nose, and Throat Specialists in the Nose-to-Brain Pathway. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Thomas Radulesco,Elie Serrano,Justin Michel
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Identifying Factors of Operative Efficiency in Head and Neck Free Flap Reconstruction. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Muayyad Alhefzi,Jennifer Redwood,Alexandra C Hatchell,Jennifer L Matthews,William K F Hill,C David McKenzie,Shamir P Chandarana,T Wayne Matthews,Robert D Hart,Joseph C Dort,Christiaan Schrag
Importance Head and neck oncological resection and reconstruction is a complex process that requires multidisciplinary collaboration and prolonged operative time. Numerous factors are associated with operative time, including a surgeon's experience, team familiarity, and the use of new technologies. It is paramount to evaluate the contribution of these factors and modalities on operative time to facilitate
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Atypical Activation of Laryngeal Somatosensory-Motor Cortex During Vocalization in People With Unexplained Chronic Cough. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-09-01 Stephanie Misono,Jiapeng Xu,Jinseok Oh,Anna Sombrio,Ali Stockness,Arash Mahnan,Jürgen Konczak
Importance Unexplained chronic cough is common and has substantial negative quality-of-life implications, yet its causes are not well understood. A better understanding of how peripheral and central neural processes contribute to chronic cough is essential for treatment design. Objective To determine if people with chronic cough exhibit signs of abnormal neural processing over laryngeal sensorimotor
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Differences in Receipt of Immunotherapy Treatment Among Patients With Head and Neck Cancer. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-31 Shreya P Ramkumar,Arun Bhardwaj,Amila Patel,Krishnamoorthy Seetharaman,Amanda Christman,Ninad Amondikar,Dina K Abouelella,Adnan S Hussaini,Justin M Barnes,Eric Adjei Boakye,Tammara L Watts,Nosayaba Osazuwa-Peters
Importance The US Food and Drug Administration approved immune checkpoint inhibitors (immunotherapy) for select cases of head and neck squamous cell carcinoma (HNSCC) in 2016. However, it is unclear whether there are clinical or sociodemographic differences among patients receiving immunotherapy as part of their care. Given the known disparities in head and neck cancer care, we hypothesized that there
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Somatic and Germline Mutations in Atypical Parathyroid Tumors. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-31 Timothy M Ullmann,Michelle Mulder,Stephanie Davis,Taufiq Rajwani,Elham Khanafshar,Quan-Yang Duh
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Treatment Strategies and Tumor Characteristics and Overall Survival Among Patients With Anaplastic Thyroid Cancer-Reply. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-31 Shannon S Wu,Jessica L Geiger,Joseph Scharpf
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Deciphering Knowledge and Opinions of Human Papillomavirus and Human Papillomavirus Vaccination for Facilitation of Point-of-Care Vaccination in Adults. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-31 Jacob C Bloom,Nicole Kaufmann,Shirley Koss,Heather A Edwards,Rebecca B Perkins,Daniel L Faden
Importance Human papillomavirus (HPV) vaccination rates remain significantly below rates for other common childhood vaccines, which has implications for future rates of HPV-associated oropharyngeal squamous cell carcinoma (OPSCC). Objective To assess whether individuals who were aware of the association between HPV and OPSCC would be more likely to have been previously vaccinated. Design, Setting,
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Association Between Antibiotic Prescribing and Time to Diagnosis of Head and Neck Cancer. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-24 James A Gallogly,Austin T Armstrong,Jennifer V Brinkmeier,Joanne Salas,Matthew C Simpson,Henry Ideker,Ronald J Walker,Sean T Massa
Importance Diagnostic delay can negatively affect patient outcomes in head and neck cancer (HNC). Neck mass and other symptoms of undiagnosed HNC may be treated with antibiotics, delaying diagnosis and treatment, despite current clinical practice guidelines. Objective To investigate temporal trends, associated factors, and time from symptom onset to antibiotic prescribing before an HNC diagnosis. Design
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Virtual Tumor Boards for Remote Learning in Head and Neck Surgical Oncology. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-24 Michael R Papazian,Michael Chow,Donald Weed,Jeffrey C Liu,Arnaud F Bewley,Michael G Moore,Babak Givi
Importance In addition to their patient management value, multidisciplinary tumor boards have been recognized as effective learning tools. However, the value of using a virtual tumor board as a learning tool for head and neck surgical oncology fellows has not been studied. Objective To describe the structure and content of the American Head and Neck Society (AHNS) Virtual Tumor Board and assess its
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Antibiotic Prescribing Prior to Head and Neck Cancer Diagnosis-Warning, Detour Ahead. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-24 Evan M Graboyes,Gerald E Harmon,Eugene G Brown
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Dysphagia Outcomes Before and After Adenotonsillectomy in Children With Obstructive Sleep Apnea: A Secondary Analysis of a Randomized Clinical Trial. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-17 Chao Wang,Huiying Hu,Kai Sun,Yulong Ma,Yuanyuan Lu,Kai Liu,Zhenkun Yu
Importance Obstructive sleep apnea (OSA) and tonsil hypertrophy may be associated with dysphagia. However, randomized clinical trials assessing dysphagia outcomes in children randomized to adenotonsillectomy (AT) vs watchful waiting with supportive care (WWSC) are lacking. Objective To assess dysphagia outcomes in children with OSA and tonsil hypertrophy managed with AT or WWSC. Design, Setting, and
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Monitoring Adverse Effects of Radiation Therapy in Patients With Head and Neck Cancer: The FACT-HN-RAD Patient-Reported Outcome Measure. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-17 Laila A Gharzai,Michelle L Mierzwa,John Devin Peipert,Kedar Kirtane,Keith Casper,Poonam Yadav,Nan Rothrock,David Cella,Sara Shaunfield
Importance Patients undergoing radiation therapy (RT) for head and neck squamous cell carcinoma (HNSCC) experience a range of debilitating adverse effects (AEs). Patient-reported outcome (PRO) measures to quantify these AEs are a necessary and important component of health care; however, currently available PRO options often measure only disease-related symptoms or AEs of non-RT treatments. Objective
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Uvular Lesion in a 62-Year-Old Man. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-17 Tara Talebi-Talghian,Nsangou Ghogomu
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Mastoiditis in a Patient With Seizures. JAMA Otolaryngol. Head Neck Surg. (IF 7.8) Pub Date : 2023-08-10 Cody Moezzi,Bradley Pickett