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Treatment of pigmented fungiform papillae of the tongue with 694 nm Q‐switched ruby laser Laser. Surg. Med. (IF 2.4) Pub Date : 2024-03-13 Joy Tao, David A. Hashemi, Jordan V. Wang, Roy Geronemus, Ronald Shelton
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest.
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Combined microfocused ultrasound and delicate pulsed light for facial rejuvenation: A prospective, randomized, and split‐face study Laser. Surg. Med. (IF 2.4) Pub Date : 2024-03-11 Yawen Wang, Jingchen Liang, Ying Chen, Jun Xia, Yanting Liu, Jing Liu, Youbao Li, Mengyao Yang, Zhao Wang, Weihui Zeng
ObjectivesPublic's interest in noninvasive skin rejuvenation treatments continues to grow. The advantage of combination therapy lies in that it can target different aspects of skin rejuvenation. This study aimed to assess the efficacy and safety of microfocused ultrasound (MFU) combined with delicate pulsed light (DPL) for facial rejuvenation.MethodsTwenty‐one patients with facial relaxation were enrolled
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Efficacy and safety of 1064‐nm fractional picosecond laser for the treatment of postmastectomy scars in transgender men: A randomized controlled trial Laser. Surg. Med. (IF 2.4) Pub Date : 2024-03-04 Suthinee Rutnin, Tanat Yongpisarn, Nawara Sakpuwadol, Amornrut Namasondhi, Cherrin Pomsoong, Teerapong Rattananukrom, Kunlawat Thadanipon
ObjectivesSubcutaneous mastectomy is a crucial component of gender affirmation therapy for transgender men (TM), but the scars that result from this procedure can frequently impair their quality of life. This study aimed to assess the efficacy and safety of 1064‐nm fractional picosecond laser (FxPico) treatment for hypertrophic and atrophic postmastectomy scars in TM.MethodsTwenty‐two patients with
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Wavelength‐dependent threshold fluences for melanosome disruption to evaluate the treatment of pigmented lesions with 532‐, 730‐, 755‐, 785‐, and 1064‐nm picosecond lasers Laser. Surg. Med. (IF 2.4) Pub Date : 2024-03-04 Yu Shimojo, Takahiro Nishimura, Daisuke Tsuruta, Toshiyuki Ozawa, Henry Hin Lee Chan, Taro Kono
Background and ObjectivesA threshold fluence for melanosome disruption has the potential to provide a robust numerical indicator for establishing clinical endpoints for pigmented lesion treatment using a picosecond laser. Although the thresholds for a 755‐nm picosecond laser were previously reported, the wavelength dependence has not been investigated. In this study, wavelength‐dependent threshold
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Proactive esophageal cooling during laser cardiac ablation: A computer modeling study Laser. Surg. Med. (IF 2.4) Pub Date : 2024-03-04 Tatiana Gomez Bustamante, Marcela Mercado Montoya, Enrique Berjano, Ana González‐Suárez, Erik Kulstad
Background and ObjectivesLaser ablation is increasingly used to treat atrial fibrillation (AF). However, atrioesophageal injury remains a potentially serious complication. While proactive esophageal cooling (PEC) reduces esophageal injury during radiofrequency ablation, the effects of PEC during laser ablation have not previously been determined. We aimed to evaluate the protective effects of PEC during
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The 730 nm picosecond titanium sapphire laser for treatment of café‐au‐lait macules in all skin types Laser. Surg. Med. (IF 2.4) Pub Date : 2024-02-28 Joan K. Fernandez, Emily L. Guo, Heather Richmond, Paul M. Friedman
ObjectivesCafé‐au‐lait macules (CALM) are benign birthmarks presenting as uniformly pigmented, well demarcated, brown patches that can be distressing to patients, especially when located in cosmetically sensitive areas. As with all pigmentary lesions in skin of color patients, CALMs have been particularly challenging to treat. Here we present the first case series characterizing treatment parameters
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Vectorized facial skin tightening: A study on the Thermal Thread Technique™ utilizing high‐intensity, high‐frequency, parallel ultrasound beam Laser. Surg. Med. (IF 2.4) Pub Date : 2024-02-27 Kentaro Oku
BackgroundFacial skin tightening with wrinkle/fine line reduction is a highly demanded procedure in the aesthetic field. Although there are studies focused on the types of energy sources, the total amount of thermal energy, and the affected depth, there have been no reports examining the relationship between the shape of thermal energy and the directivity of skin tightening. We have developed a specific
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Ablative fractional CO2 laser treatment promotes wound healing phenotype in skin macrophages Laser. Surg. Med. (IF 2.4) Pub Date : 2024-02-26 Martin Wiinberg, Thomas L. Andresen, Merete Haedersdal, Uffe H. Olesen
Ablative fractional laser (AFL) treatment is a well-established method for reducing signs of skin photoaging. However, the biological mechanisms underlying AFL-induced healing responses and skin rejuvenation remain largely unknown. It is known that macrophages play an important role in orchestrating healing, normalization, and remodeling processes in skin. Macrophage phenotypes are characterized by
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Time-resolved fluorescence and diffuse reflectance for lung squamous carcinoma margin detection Laser. Surg. Med. (IF 2.4) Pub Date : 2024-02-15 Sarah Costa, Qiyin Fang, Thomas Farrell, Erica Dao, Michael Farquharson
A major challenge in non-small cell lung cancer surgery is the occurrence of positive tumor margins. This may lead to the need for additional surgeries and has been linked to poor patient prognosis. This study aims to develop an in vivo surgical tool that can differentiate cancerous from noncancerous lung tissue at the margin.
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Full-face and neck resurfacing with a novel ablative fractional 2910 nm erbium-doped fluoride glass fiber laser for advanced photoaging Laser. Surg. Med. (IF 2.4) Pub Date : 2024-02-14 Taryn N. Murray, Jamie K. Hu, Paul M. Friedman
Ablative fractional lasers have long been considered the gold standard for facial resurfacing for advanced photoaging. These lasers offer an improved safety profile compared to traditional ablative lasers but typically require more treatment sessions given their fractional approach. In this study, we evaluate a new novel 2910 nm erbium-doped fluoride glass fiber laser (2910 nm fiber laser) (UltraClear;
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Neck and chest rejuvenation with fractional 1440 and 1927-nm low-powered diode laser Laser. Surg. Med. (IF 2.4) Pub Date : 2024-02-09 Lauren Hoffman, Eleanor Smeallie, Nkem Ugonabo, Anne Chapas
Ultraviolet light and infrared radiation exposure to the chest and neck can result in photoaging changes, such as rhytids, skin roughness, and dyschromia, which can be treated with nonablative fractionated lasers. The low-powered fractionated 1440 and 1927-nm diode lasers have been shown to safely reduce facial photodamage. This study was conducted to investigate the safety and efficacy of a low-powered
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Histological evaluation of monopolar and bipolar radiofrequency microneedling treatment in a porcine model Laser. Surg. Med. (IF 2.4) Pub Date : 2024-02-09 Hao Wang, Michael R. Hamblin, Yi Zhang, Yidan Xu, Xiang Wen
Fractional radiofrequency microneedling (FRM) is widely used as an option for skin rejuvenation, however there is a lack of histological evidence for the various energy delivery systems available. The objective was to assess thermal denaturation of tissue and the wound healing response in monopolar mode versus bipolar mode. Histological analysis was performed to demonstrate the efficacy of automatic
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Laser-assisted topical delivery of vismodegib reduces hedgehog gene expression in human basal cell carcinomas in vivo Laser. Surg. Med. (IF 2.4) Pub Date : 2024-02-04 Uffe H. Olesen, Kristian Kåber Pedersen, Katrine Togsverd-Bo, Edyta Biskup, Anni Linnet Nielsen, Malene Jackerott, Gael Clergeaud, Thomas L. Andresen, Merete Haedersdal
Systemically delivered hedgehog inhibitors including vismodegib and sonidegib are widely used to treat basal cell carcinomas (BCCs). Ablative fractional laser (AFL)-assisted topical delivery of vismodegib has been demonstrated in preclinical studies. The aim of this explorative clinical study was to evaluate intratumoral vismodegib concentrations and effect on hedgehog pathway gene expression following
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Histological examination of skin tissue in the porcine animal model after application of a new monopolar radiofrequency Laser. Surg. Med. (IF 2.4) Pub Date : 2024-02-02 Chong Zhang, Meng Wang, Yi Li, Yan Yan
This study aims to evaluate the safety of the radiofrequency device and its efficacy in various treatment and refrigeration modes.
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Selective neural inhibition via photobiomodulation alleviates behavioral hypersensitivity associated with small sensory fiber activation Laser. Surg. Med. (IF 2.4) Pub Date : 2024-01-30 Andrew Buzza, Kalista Tapas, Junqi Zhuo, Juanita J. Anders, Stephen J. Lewis, Michael W. Jenkins, Michael Moffitt
Photobiomodulation at higher irradiances has great potential as a pain-alleviating method that selectively inhibits small diameter nerve fibers and corresponding sensory experiences, such as nociception and heat sensation. The longevity and magnitude of these effects as a function of laser irradiation parameters at the nerve was explored.
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Efficacy and safety of fractional microneedle radiofrequency for atrophic acne scars: A real-world clinical study of 126 patients Laser. Surg. Med. (IF 2.4) Pub Date : 2024-01-28 Ziwei Ding, Yuan Guo, Yuehong Guo, Yanqiu Tang, Xufeng Yin, Hui Hua, Zhanchao Zhou, Bingrong Zhou
To analyze the clinical efficacy and safety of fractional microneedle radiofrequency (FMR) for facial atrophic acne scars in a real-world setting.
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Hyperspectral imaging for monitoring of free flaps of the oral cavity: A feasibility study Laser. Surg. Med. (IF 2.4) Pub Date : 2024-01-21 Axelle Felicio-Briegel, Matthäus Linek, Ronald Sroka, Adrian Rühm, Christian Freymüller, Magdalena Stocker, Philipp Baumeister, Christoph Reichel, Veronika Volgger
Hyperspectral imaging (HSI) provides spectral information about hemoglobin, water and oxygen supply and has thus great potential in perfusion monitoring. The aim of the present study was to investigate the feasibility of HSI in the postoperative monitoring of intraoral free flaps.
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The use of fractional radiofrequency in Asian patients to improve skin texture Laser. Surg. Med. (IF 2.4) Pub Date : 2024-01-21 Mandy W. M. Chan, Agnes W. S. Chan, Christina S. M. Wong, Samantha Y. N. Shek, Chi Keung Yeung, Taro Kono, Henry H. L. Chan
Fractional radiofrequency devices have been demonstrated to improve skin texture, such as smoothness, rhytides, brightness, and atrophic acne scars, by increasing dermal thickness, dermal collagen content, and dermal fibrillin content. The objective of the study is to assess the efficacy and adverse effects of this device on Asian patients of skin type III and IV with skin textural changes.
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Novel 40 µm spot size 3050/3200 nm DFG laser versus CO2 laser for laser-assisted drug delivery Laser. Surg. Med. (IF 2.4) Pub Date : 2024-01-16 Parita T. Suwan, Ga Ram Ahn, Roger Sumner, Dilip Paithankar, Ilya V. Yaroslavsky, Gregory Altshuler, Valeriya Arkhipova, Dieter Manstein, Michael Wang-Evers
The use of ablative fractional lasers to enhance the delivery of topical drugs through the skin is known as laser-assisted drug delivery. Here, we compare a novel 3050/3200 nm difference frequency generation (DFG) fiber laser (spot size: 40 µm) to a commercially used CO2 laser (spot size: 120 µm). The objective is to determine whether differences in spot size and coagulation zone (CZ) thickness influence
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Treatment of hypopigmented burn hypertrophic scars with short-term topical tacrolimus does not lead to repigmentation Laser. Surg. Med. (IF 2.4) Pub Date : 2024-01-15 Esteban A. Molina, Taryn E. Travis, Lou'ay Hussein, Mary A. Oliver, John W. Keyloun, Lauren T. Moffatt, Jeffrey W. Shupp, Bonnie C. Carney
Dyschromia is an understudied aspect of hypertrophic scar (HTS). The use of topical tacrolimus has successfully shown repigmentation in vitiligo patients through promotion of melanogenesis and melanocyte proliferation. It was hypothesized that HTSs treated with topical tacrolimus would have increased repigmentation compared to controls.
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Long-term efficacy and safety of nonablative monopolar radiofrequency in the treatment of moderate to severe acne vulgaris Laser. Surg. Med. (IF 2.4) Pub Date : 2024-01-14 Woraphong Manuskiatti, Supisara Wongdama, Noldtawat Viriyaskultorn, Jayne Bernadeth Li, Kanokvalai Kulthanan, Thanya Techapichetvanich
Acne vulgaris (AV) is a prevalent skin condition known for its potential to cause scarring and psychological distress, often leading to diminished self-esteem. While topical and oral treatments are commonly prescribed, some patients experience treatment failure, adverse effects, or contraindications to conventional therapies. In response to these challenges, laser and energy-based device therapies
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Line-field confocal optical coherence tomography for in vivo visualization of morphological characteristics of squamous cell carcinoma in a murine model Laser. Surg. Med. (IF 2.4) Pub Date : 2023-12-21 Uffe H. Olesen, Camilla Foged, Kevin Jacobsen, Vinzent K. Ortner, Gabriella Fredman, Uwe Paasch, Merete Haedersdal
Non-invasive imaging with line-field confocal optical coherence tomography (LC-OCT) can support the diagnosis of squamous cell carcinoma (SCC) through visualization of morphological characteristics specific to skin cancer. We aimed to visualize prominent morphological characteristics of SCC using LC-OCT in a well-established murine SCC model.
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Corneal wound healing following infrared laser irradiation at the wavelengths of 1.319 and 10.6 μm Laser. Surg. Med. (IF 2.4) Pub Date : 2023-12-17 Congling Zhou, Yixue Yin, Jiarui Wang, Ziqi Ren, Luguang Jiao, Li Zhong, Zaifu Yang
To investigate the wound healing of rabbit cornea following infrared laser irradiations at the wavelengths of 1.319 and 10.6 μm.
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Cover Image: Volume 55 Issue 10 Laser. Surg. Med. (IF 2.4) Pub Date : 2023-12-13 Arsham Hamidi, Yakub A. Bayhaqi, Sandra Drusová, Alexander A. Navarini, Philippe C. Cattin, Ferda Canbaz, Azhar Zam
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Spectral effects and enhancement quantification in healthy human saliva with surface-enhanced Raman spectroscopy using silver nanopillar substrates Laser. Surg. Med. (IF 2.4) Pub Date : 2023-12-10 Esmat Zamani, Nassim Ksantini, Guillaume Sheehy, Katherine J. I. Ember, Bill Baloukas, Oleg Zabeida, Tran Trang, Myriam Mahfoud, Jolanta-Ewa Sapieha, Ludvik Martinu, Frédéric Leblond
Raman spectroscopy as a diagnostic tool for biofluid applications is limited by low inelastic scattering contributions compared to the fluorescence background from biomolecules. Surface-enhanced Raman spectroscopy (SERS) can increase Raman scattering signals, thereby offering the potential to reduce imaging times. We aimed to evaluate the enhancement related to the plasmonic effect and quantify the
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Analysis of lithotripsy efficiency and stone retropulsion displacement according to pulse characteristics of Ho: YAG laser with Moses effect Laser. Surg. Med. (IF 2.4) Pub Date : 2023-11-30 Kanghae Kim, Young-Seok Seo, Phil-Sang Chung, Joo Beom Eom
Compared to the conventional Ho: YAG laser, a Ho: YAG laser device has been reported that has a Moses effect to reduce stone retropulsion and increase lithotripsy efficiency. The principle of this equipment is to convert a single laser pulse into two pulses. Most studies on such lasers are limited to lithotripsy efficiency and the prevention of stone retropulsion; studies according to each pulse condition
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Fluence is unequal to incident energy density or radiant exposure. Laser. Surg. Med. (IF 2.4) Pub Date : 2023-11-29 Martin J C van Gemert,Ton G van Leeuwen
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Fractional non-ablative assisted bimatoprost delivery: A synergistic approach for treating post-inflammatory hypopigmentation following cosmetic procedures in skin of color patients. Laser. Surg. Med. (IF 2.4) Pub Date : 2023-11-29 Kelli Jablon,Erin Theisen,Sarah H Hsu,Jeffrey S Dover,Hye Jin Chung
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Evaluation of thermodynamic bioeffects of long-pulsed 1064 nm laser in the photothermal lipolysis Laser. Surg. Med. (IF 2.4) Pub Date : 2023-11-29 Shan Wu, Zhixuan Jiang, Jiying Dong, Min Yao
To evaluate the lipolysis effect of air cooling assisted long-pulsed 1064 laser for improving local adiposity.
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Comparison of quartz and sapphire optical chambers for infrared laser sealing of vascular tissues using a reciprocating, side-firing optical fiber: Simulations and experiments Laser. Surg. Med. (IF 2.4) Pub Date : 2023-11-27 Woheeb M. Saeed, Patrick J. O'Brien, Jude Yoshino, Aidan R. Restelli, Alexandria J. Traynham, Nathaniel M. Fried
Infrared (IR) lasers are being tested as an alternative to radiofrequency (RF) and ultrasonic (US) surgical devices for hemostatic sealing of vascular tissues. In previous studies, a side-firing optical fiber with elliptical IR beam output was reciprocated, producing a linear IR laser beam pattern for uniform sealing of blood vessels. Technical challenges include limited field-of-view of vessel position
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Impact of skin hydration on patterns of microthermal injury produced by fractional CO2 laser Laser. Surg. Med. (IF 2.4) Pub Date : 2023-11-21 Emily Wenande, Anna Hastrup, Gabriella Louise Fredman, Uffe Høgh Olesen, Albert Wolkerstorfer, Merete Haedersdal
The impact of skin hydration on patterns of thermal injury produced by ablative fractional lasers (AFLs) is insufficiently examined under standardized conditions. Using skin with three different hydration levels, this study assessed the effect of hydration status on microchannel dimensions generated by a fractional CO2 laser.
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Influence of tissue desiccation on critical temperature for thermal damage during Er:YAG laser skin treatments Laser. Surg. Med. (IF 2.4) Pub Date : 2023-11-16 Matjaž Lukač, Jure Košir, Tilen Žel, Marko Kažič, Dominik Šavli, Matija Jezeršek
Erbium lasers have become an accepted tool for performing both ablative and non-ablative medical procedures, especially when minimal invasiveness is desired. Hard-tissue desiccation during Er:YAG laser procedures is a well-known phenomenon in dentistry, the effect of which is to a certain degree being addressed by the accompanying cooling water spray. The desiccation of soft tissue has attracted much
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LASERS: Where we began, where we have gone, where we are now. Where will we go? Laser. Surg. Med. (IF 2.4) Pub Date : 2023-11-13 Lou Reinisch
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LC-OCT imaging and application to energy based device therapy. Laser. Surg. Med. (IF 2.4) Pub Date : 2023-11-08 Thomas M Beachkofsky,James M Grichnik,Peter R Shumaker
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Needle-free electronically-controlled jet injector treatment with bleomycin and lidocaine is effective and well-tolerated in patients with recalcitrant keloids Laser. Surg. Med. (IF 2.4) Pub Date : 2023-11-07 Vazula Zulfra Bekkers, Fatima Khan, Pim Aarts, Katarzyna Zdunczyk, Errol Prospero Prens, Albert Wolkerstorfer, Robert Rissmann, Martijn Bastiaan Adriaan van Doorn
The treatment of recalcitrant keloids is challenging. Although intralesional bleomycin using conventional needle injectors (CNI) is effective, it has important drawbacks, such as the need for repetitive and painful injections. Therefore, we aimed to evaluate the effectiveness, tolerability and patient satisfaction of intralesional bleomycin with lidocaine administered with a needle-free electronically-controlled
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Comments on "Melasma treatment with a 1064 nm, picosecond-domain laser with a fractionated multibeam lens array". Laser. Surg. Med. (IF 2.4) Pub Date : 2023-10-27 Manoj Pawar,Assel Satvaldinova,Mehak Singh
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Cover Image: Volume 55 Issue 9 Laser. Surg. Med. (IF 2.4) Pub Date : 2023-10-23 Eric F. Bernstein, Lisa D. Basilavecchio, Jenny Wang
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Multimodal feedback systems for smart laser osteotomy: Depth control and tissue differentiation Laser. Surg. Med. (IF 2.4) Pub Date : 2023-10-23 Arsham Hamidi, Yakub A. Bayhaqi, Sandra Drusová, Alexander A. Navarini, Philippe C. Cattin, Ferda Canbaz, Azhar Zam
The study aimed to improve the safety and accuracy of laser osteotomy (bone surgery) by integrating optical feedback systems with an Er:YAG laser. Optical feedback consists of a real-time visual feedback system that monitors and controls the depth of laser-induced cuts and a tissue sensor differentiating tissue types based on their chemical composition. The developed multimodal feedback systems demonstrated
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Biological effect of laser-assisted scar healing (LASH) on standardized human three-dimensional wound healing skin models using fractional non-ablative 1540 nm Er:Glass or 1550 nm diode lasers Laser. Surg. Med. (IF 2.4) Pub Date : 2023-10-19 Helena I. Riedemann, Yvonne Marquardt, Manuela Jansen, Jens M. Baron, Sebastian Huth
In postoperative wound healing after surgical operations or ablative laser treatments, recent studies suggest the timely use of non-ablative fractional laser treatments with the aim to improve wound healing and prevent pathological scar formation. However, the underlying molecular mechanisms are poorly understood. The aim of this study was to investigate the effects of laser-assisted scar healing (LASH)
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Single treatment scar resurfacing with a novel ablative fractional 2910 nm erbium-doped fluoride glass fiber laser Laser. Surg. Med. (IF 2.4) Pub Date : 2023-10-17 Taryn N. Murray, Emily L. Guo, Heather Richmond, Paul M. Friedman
INTRODUCTION Scars are a common dermatologic complaint that can adversely affect an individual's quality of life. With diverse etiologies and types of scars, treatment is often challenging. Myriad treatment options exist ranging from topical medications to surgical revision, however, no scar treatment has been as revolutionary as lasers. Since its introduction, ablative laser resurfacing technology
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Modified painless photodynamic therapy for facial multiple actinic keratosis in China: A prospective split-face control study Laser. Surg. Med. (IF 2.4) Pub Date : 2023-10-09 Jiandan Li, Yunfeng Zhang, Guolong Zhang, Linglin Zhang, Zhongxia Zhou, Peiru Wang, Xiuli Wang
Aminolevulinic acid photodynamic therapy (ALA-PDT) is an effective treatment for multiple actinic keratosis (AK). However, PDT-induced pain often discontinues the therapy to reduce its efficacy, limiting its application. If modified painless PDT schedule with shorter photosensitizer dressing and higher dose illumination could achieve good efficacy in AK, it is still unknown.
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Conventional drilling versus ultrasound and laser osteotomy in mandibular third molar surgery: A comparative study Laser. Surg. Med. (IF 2.4) Pub Date : 2023-10-09 Bistra Blagova, Dimo Krastev, Lina Malinova
There are few research works with in-depth studies and direct simultaneous comparisons of the effects on tissue reactions and patients' recovery following in vivo conventional drilling, ultrasound- and laser-assisted osteotomy in humans.
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Rational of topical photodynamic therapy (PDT) with 5-aminolevulinic acid (5-ALA) for treatment of endocervical canal low-grade squamous intraepithelial lesion with high-risk human papillomavirus infection Laser. Surg. Med. (IF 2.4) Pub Date : 2023-09-26 Lin-Jing Yuan, Ke He, Cai-Xia Zhu, Tie-Feng Cao, Mian He
The detection and continuous monitoring of low-grade squamous intraepithelial lesions (LSIL) within the endocervical canal pose considerable challenges, and the effectiveness of ablation treatment is also constrained. In this context, the potential efficacy of 5-aminolevulinic acid photodynamic therapy (5-ALA PDT) in targeting these concealed lesions merits exploration. The present study undertakes
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Balloon-assisted laser application for endoscopic treatment of biliary stricture Laser. Surg. Med. (IF 2.4) Pub Date : 2023-09-20 Seonghee Lim, Van Gia Truong, Seok Jeong, Jiho Lee, Byeong-il Lee, Hyun Wook Kang
Malignant biliary stricture is a ductal narrowing of the bile duct that is often diagnosed at an advanced stage, leading to difficulty in resection. The current study aims to evaluate the feasibility of endobiliary laser treatment by quantifying the extent of coagulative necrosis in tissue under various conditions.
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Comparing safety and efficacy of acoustic subcision at two different rapid acoustic pulse rates to improve the appearance of cellulite Laser. Surg. Med. (IF 2.4) Pub Date : 2023-09-11 Brian S. Biesman, Christopher C. Capelli
A recent study showed the safety and efficacy of a noninvasive acoustic subcision device to improve the appearance of cellulite via delivery of rapid acoustic pulses in a single treatment visit.
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Correlation between the efficacy of picosecond-domain laser treatment for solar lentigo and the vascularity in the upper dermis using optical coherence tomography angiography in Asian women Laser. Surg. Med. (IF 2.4) Pub Date : 2023-09-07 Yusuke Hara, Masato Ninomiya, Toyonobu Yamashita, Kei Negishi
The purpose of this study was to noninvasively confirm the characteristics of the dermal vasculature in patients with solar lentigo (SL) and determine any association with the efficacy of picosecond-domain laser (PSL) treatment.
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Melasma treatment with a 1064 nm, picosecond-domain laser with a fractionated multibeam lens array Laser. Surg. Med. (IF 2.4) Pub Date : 2023-09-05 Eric F. Bernstein, Lisa D. Basilavecchio, Jenny Wang
Picosecond-domain lasers have been fitted with fractionated optics for dermal remodeling. This study evaluates the safety and efficacy of a multiwavelength picosecond-domain laser, using a 1064 nm multibeam lens array, for improving the appearance of melasma.
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Split-face study to evaluate efficacy of global cryomodulation for reduction of pain and inflammation after nonablative fractional resurfacing Laser. Surg. Med. (IF 2.4) Pub Date : 2023-09-03 Taryn N. Murray, Kavita Darji, Paul M. Friedman
Cryomodulation, or the delivery of controlled cooling to downregulate inflammatory processes in the skin, has been proposed to mitigate acute side effects following various dermatologic treatments. A new controlled cooling device has been developed to deliver cryomodulation for a range of different indications. In this clinical study, we evaluate the device for the reduction of pain, erythema, and
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Objective monitoring of laser tattoo removal in human volunteers using an innovative optical technique: A proof of principle Laser. Surg. Med. (IF 2.4) Pub Date : 2023-09-01 Neža Golmajer Zima, Nina Verdel, Matjaž Lukač, Boris Majaron
Assess the suitability of the technique for objective monitoring of laser tattoo removal by an extended treatment protocol.
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Corneal damage threshold induced by supercontinuum source: A further study Laser. Surg. Med. (IF 2.4) Pub Date : 2023-09-01 Luguang Jiao, Chao Wang, Jiarui Wang, Zaifu Yang
Previous report shows that corneal spot size is an important influence factor on damage threshold induced by supercontinumm (SC) source. However, damage thresholds were determined for the spot size of only 0.37 mm due to the low output of the employed SC source at that time. The objectives of this study are to determine the lowest possible corneal damage threshold at a large corneal spot size using
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Needleless laser injector versus needle injection for skin enhancement and rejuvenation effect of dermal filler Laser. Surg. Med. (IF 2.4) Pub Date : 2023-08-26 Hye Sung Han, Bo Ri Kim, Minjae Kim, Jung-Im Na, Suk Bae Seo, Chang-Hun Huh, Jung-Won Shin
A needleless laser-induced microjet injector is a novel transdermal drug delivery system that can rapidly inject a very small and precise drug dose into the skin with minimal pain and downtime. In this study, we aimed to compare the laser-induced microjet injection versus needle injection of polylactic acid/hyaluronic acid filler for skin enhancement and rejuvenation.
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Combining superpulse dynamic CO2 laser and supramolecular salicylic acid in the treatment of dense comedones with higher clearance in a shorter time: A prospective, randomized, split-face clinical trial Laser. Surg. Med. (IF 2.4) Pub Date : 2023-08-15 Meng-yao Yang, Jing Liu, Di-chao Ning, Yan-ting Liu, Dan Ye, Chen Tu, Zhao Wang, Wei-Hui Zeng
Dense comedones are common in patients with acne vulgaris, and promoting treatment can prevent the progression of acne lesions. However, the efficacy-time conflict makes the treatment challenging and the medication options are limited by the side effects.
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Fractional ablative CO2 laser and oral isotretinoin—A prospective randomized controlled split-face trial comparing concurrent versus delayed laser treatment for acne scars Laser. Surg. Med. (IF 2.4) Pub Date : 2023-08-09 Eyal Taleb, Elisa S. Gallo, Fares Salameh, Amir Koren, Waseem Shehadeh, Ofir Artzi
Therapeutic dogma has been to treat acne scars with ablative fractional laser no less than 6 months after isotretinoin (ITN) cessation.
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Real-time laser speckle contrast imaging measurement during normothermic machine perfusion in pretransplant kidney assessment Laser. Surg. Med. (IF 2.4) Pub Date : 2023-08-09 Yitian Fang, Lisanne van Ooijen, Gisela Ambagtsheer, Anton V. Nikolaev, Marian C. Clahsen-van Groningen, Jenny Dankelman, Ron W. F. de Bruin, Robert C. Minnee
Normothermic machine perfusion (NMP) provides a platform for pre-transplant kidney quality assessment that is essential for the use of marginal donor kidneys. Laser speckle contrast imaging (LSCI) presents distinct advantages as a real-time and noncontact imaging technique for measuring microcirculation. In this study, we aimed to assess the value of LSCI in visualizing renal cortical perfusion and
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Full-thickness skin rejuvenation by a novel dual-length microneedle radiofrequency device: A proof-of-concept study using human skin Laser. Surg. Med. (IF 2.4) Pub Date : 2023-08-07 Ga Ram Ahn, You Na Jang, So Young Lee, Woo Ju Kim, Hye Sung Han, Kwang Ho Yoo, Tae Hui Bae, Jaesang Barn, Joon Seok, Beom Joon Kim
A novel dual-length microneedle radiofrequency (DLMR) device has been developed to achieve full-thickness skin rejuvenation by stimulating the papillary and reticular dermis simultaneously. This device's dual-level targeting concept need to be validated on human skin, although its clinical efficacy has been demonstrated in a previous study.
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Prospective study to assess the efficacy and safety of a noninvasive electro-muscular stimulation for improvement of muscle strength and muscle toning of the extremities Laser. Surg. Med. (IF 2.4) Pub Date : 2023-08-07 Nkem Ugonabo, Pooja H. Rambhia, Janet You, Omar A. Ibrahimi, Anne Chapas
We sought to evaluate the safety and efficacy of an electrical muscle stimulation (EMS) device in the improvement of muscle strength and toning of the upper extremities. This device, which is FDA-cleared as a two-channel muscle stimulator, provides up to eight electrodes with waveforms inducing muscle stimulation. Although a prior study demonstrated it is safe and effective for use in the abdomen,
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Breast tissue analysis using a clinically compatible combined time-resolved fluorescence and diffuse reflectance (TRF-DR) system Laser. Surg. Med. (IF 2.4) Pub Date : 2023-08-01 Erica Dao, Gabriela Gohla, Phillip Williams, Peter Lovrics, Fares Badr, Qiyin Fang, Thomas Farrell, Michael Farquharson
This work aims to develop a clinically compatible system that can perform breast tissue analysis in a more time efficient process than conventional histopathological assessment. The potential for such a system to be used in vivo in the operating room or surgical suite to improve patient outcome is investigated.
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Clinical evaluation of a new fractional ablative 2910 nm erbium laser on photodamaged skin: A pilot study Laser. Surg. Med. (IF 2.4) Pub Date : 2023-08-01 Mona M. Selim, Joseph A. Lowery, Hasina S. Maredia, Brian D. Zelickson
To examine the efficacy and safety of a new fractional, ablative erbium:glass fiber (Er:glass) laser (2910 nm) at improving clinical signs of photodamaged skin.