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Surgical Outcomes of Ipsilateral Inguinal Hernia After Kidney Transplantation Transplant. Proc. (IF 0.9) Pub Date : 2024-03-15 Hirosuke Ishikawa, Takashi Kobayashi, Kohei Miura, Masayuki Tasaki, Kazuhide Saito, Kazuyasu Takizawa, Jun Sakata, Toshifumi Wakai
We aimed to clarify the clinical features and outcomes of ipsilateral inguinal hernias after kidney transplantation. Eleven patients diagnosed with inguinal hernia on the ipsilateral side after kidney transplantation between 2011 and 2022 were analyzed. Clinical data were retrospectively reviewed from the medical records. Eleven patients were included in the analysis (median age, 68 [range, 28-75]
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The Effect of Induction Therapy on Antibody-Mediated Rejection in Kidney Transplantation: A Network Meta-Analysis Using Recent Data Transplant. Proc. (IF 0.9) Pub Date : 2024-03-14 Jin Ho Lee, Heeryong Lee, Kipyo Kim, Seoung Woo Lee, Joon Ho Song, Seun Deuk Hwang
Various induction regimens are available for kidney transplantation (KT); however, which is superior remains unclear. Moreover, although the induction regimens are effective and important for reducing side effects, their respective relationships with antibody-mediated rejection (AMR) after transplantation remain unclear. Therefore, this study aimed to elucidate the most effective induction regimen
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Donation and Equitable Access to Organ, Tissue, and Cell Transplants: A Brazilian Perspective on the Strategy and Plan of Action 2019-2030 Transplant. Proc. (IF 0.9) Pub Date : 2024-03-12 Bartira de Aguiar Roza, Sibele Maria Schuantes-Paim, Mônica Campos Daibert, Karina Dal Sasso Mendes, Neide da Silva Knihs, Patrícia Treviso, Janine Schirmer, Isabel Cristina Kowal Olm Cunha
To position the Brazilian Transplant System within the context of the 4 Strategic Lines of Action proposed by the Pan-American Health Organization. A specialist analysis was conducted through comparative analyses of the 4 Strategic Lines of Action, objectives, and indicators outlined in the Action Plan, along with the donation and transplantation system in accordance with Brazilian transplantation
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Organ Procurement From Foreigners Who Died in Poland and Organ Transplantation to Foreigners Transplant. Proc. (IF 0.9) Pub Date : 2024-03-12 Anna Pszenny, Adam Parulski, Małgorzata Hermanowicz, Jolanta Przygoda, Dorota Lewandowska, Teresa Danek, Ewa Danielewska, Jarosław Czerwiński, Artur Kamiński
The aim of the work was to present data concerning organ donation from and transplantation to foreigners in Poland. Data came from registries maintained by the Polish Transplant Coordinating Center POLTRANSPLANT, consisting of the national waiting list, deceased donor registry, transplant registry, and live donor registry.
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Experience with Tandem Pre-Dilution Online Hemodiafiltration and Centrifugal Plasma Exchange in Pretransplant Desensitization for Abo-Incompatible Kidney Transplantation: A Case Report Transplant. Proc. (IF 0.9) Pub Date : 2024-03-12 Kazuki Masuda, Toshihide Naganuma, Takuya Torigoe, Kazuya Kabei, Yuichi Machida, Tomoaki Iwai, Yoshiaki Takemoto, Junji Uchida
In the use of therapeutic plasma exchange (TPE) as antibody removal therapy for ABO-incompatible (ABOi) kidney transplantation, it is technically possible to perform online hemodiafiltration (OHDF) and TPE simultaneously for patients who are receiving OHDF. In this study, we report tandem therapy of pre-dilution OHDF and centrifugal plasma exchange (cTPE), instead of membrane plasma exchange, which
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Drug-Eluting Bead Transarterial Chemoembolization for Hepatocellular Carcinoma: The Effectiveness of Different Particle Sizes in Downstaging and Bridging in Living Donor Liver Transplantation Transplant. Proc. (IF 0.9) Pub Date : 2024-03-11 Wei-Xiong Lim, Kuan Siong Sim, Chao-Long Chen, Hsin-You Ou, Chun-Yen Yu, Yu-Fan Cheng
To compare the effectiveness of drug-eluting bead transarterial chemoembolization (DEB-TACE) with different particle sizes in bridging and downstaging in pretransplant hepatocellular carcinoma patients. Assess the recurrent and survival rates after living donor liver transplantation (LDLT). Retrospective review of 580 patients who underwent TACE using DEB from August 2012 to June 2020 at Taiwan Kaohsiung
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Knowledge and Attitudes of Dialysis Patients Toward Kidney Transplantation: Preliminary Report from a Pilot Study Preceding a Cross-Sectional Nationwide Evaluation Transplant. Proc. (IF 0.9) Pub Date : 2024-03-06 Paulina Kurleto, Maciej Kiersztejn, Nina Szumańska, Irena Milaniak, Lucyna Tomaszek, Grażyna Dębska, Edyta Turkanik, Barbara Siekierska, Rajmund Michalski, Aleksandra Tomaszek, Jacek A. Pietrzyk
The knowledge and attitudes of dialyzed patients toward the best method of renal replacement treatment (ie, kidney transplantation [KTx]) may be the main factor motivating them to apply and be put on the national kidney transplant waiting list, resulting in a better prognosis. Assessment of the knowledge and attitudes of dialyzed patients toward KTx. A pilot study is considered an introductory step
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Conversion From Immediate-Release to Prolonged-Release Tacrolimus in Kidney Transplant Patients With Tremor: A Case Series Study Transplant. Proc. (IF 0.9) Pub Date : 2024-03-06 Dorota Kamińska, Roman Hożejowski, Andrzej Chamienia, Alicja Dębska-Ślizień, Ilona Idasiak-Piechocka, Andrzej Oko, Iwona Baranowicz-Gąszczyk, Wojciech Załuska, Oktawia Mazanowska, Magdalena Krajewska
Tremor is common with tacrolimus treatment and is linked with peak blood drug concentrations. We investigated the effect of switching from immediate-release tacrolimus (IR-TAC) to MeltDose prolonged-release tacrolimus (LCPT) on tremor in kidney transplant recipients experiencing tremor at therapeutic levels of IR-TAC. The Activities of Daily Living Subscale (ADL, range 0-48, lower = better) of the
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Severe Bullous Erysipelas/Cellulitis, Atypically Caused by Escherichia coli, in Kidney Transplant Recipient – Case Report and Review of Literature Transplant. Proc. (IF 0.9) Pub Date : 2024-03-05 Szymczak Maciej, Augustyniak-Bartosik Hanna, Krzysztof Letachowicz, Kamińska Dorota, Banasik Mirosław, Mazanowska Oktawia, Krajewska Magdalena
Erysipelas/cellulitis are severe skin infections that are especially dangerous for immunocompromised patients. The most common cause of these diseases is streptococcal infection, but sometimes they may be caused by other Gram-positive or negative bacteria or other factors. Proper diagnosis and treatment should be implemented accurately to prevent dangerous complications. We present a case of severe
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Preoperative Intrathecal Morphine is Associated With Reduced Postoperative Pain, Agitation, and Delirium In Living Donor Kidney Transplantation Recipients Transplant. Proc. (IF 0.9) Pub Date : 2024-03-05 Ja Eun Lee, Kyo Won Lee, Eunmi Gil, Jae Berm Park, Byung Jun Kim, Ha Yeon Kim, Gaab-Soo Kim
Postoperative delirium after organ transplantation can lead to increased length of hospital stay and mortality. Because pain is an important risk factor for delirium, perioperative analgesia with intrathecal morphine (ITM) may mitigate postoperative delirium development. We evaluated if ITM reduces postoperative delirium incidence in living donor kidney transplant (LDKT) recipients. patients who received
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Immunotherapy Using Activated Natural Killer Cells Improves Postoperative Neutrophil-to-Lymphocyte Ratio and Long-Term Prognosis of Living Donor Liver Transplant Recipients With Hepatocellular Carcinoma Transplant. Proc. (IF 0.9) Pub Date : 2024-03-04 Kouki Imaoka, Masahiro Ohira, Minoru Hattori, Ichiya Chogahara, Saki Sato, Mayuna Nakamura, Tomoaki Bekki, Koki Sato, Yuki Imaoka, Ryosuke Nakano, Takuya Yano, Hiroshi Sakai, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Yuka Tanaka, Hideki Ohdan
Preoperative neutrophil-to-lymphocyte ratio (NLR) is a well-known prognostic indicator in various malignancies; however, the impact of postoperative NLR on living donor liver transplant (LDLT) recipients is unknown. Immunotherapy with donor liver-derived activated natural killer (NK) cells may improve postoperative NLR by coactivating immune cells or suppressing activated neutrophils. This study aims
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Atherosclerosis Deteriorates Liver Ischemia/Reperfusion Injury Via Interferon Regulatory Factor-1 Overexpression in a Murine Model Transplant. Proc. (IF 0.9) Pub Date : 2024-03-03 Ryosuke Nakano, Ichiya Chogahara, Masahiro Ohira, Kouki Imaoka, Saki Sato, Tomoaki Bekki, Koki Sato, Yuki Imaoka, Doskali Marlen, Yuka Tanaka, Hideki Ohdan
Abdominal aortic calcification (AAC) is associated with cardiovascular-related mortality, along with an elevated risk of coronary, cerebrovascular, and cardiovascular events. Notably, AAC is strongly associated with poor overall and recurrence free survival posthepatectomy for hepatocellular carcinoma. Despite the acknowledged significance of atherosclerosis in systemic inflammation, its response to
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Hepatocellular Carcinoma in Ceará: Epidemiology and Treatment in a Reference Liver Transplant Center in Northeast Brazil Transplant. Proc. (IF 0.9) Pub Date : 2024-02-29 P.E.G. Costa, J.H.P. Garcia, G.R. Coelho, M.A.P. Barros, E.B. Hyppolito, K.B. Pereira, T.D dos S. Rocha, G.C.G Costa
Hepatocellular carcinoma remains a significant worldwide malignancy and an important cause of cancer-related death. The incidence is increasing globally. In Latin America, there is no consistent data on the epidemiology of hepatocellular carcinoma. However, Brazil is considered a country with an intermediate incidence of this liver neoplasm. In the state of Ceará, situated in the northeast region of
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Living Donor Liver Transplantation for an Infant Having Tracheostomy and Subglottic Stenosis: A Case Report Transplant. Proc. (IF 0.9) Pub Date : 2024-02-29 Ja Eun Lee, Keoungah Kim, Ji-Hye Kwon, Gaab-Soo Kim
It is uncommon to perform liver transplantation for patients with end-stage liver disease having tracheostomy. Usually, the tracheostomy cannula is changed to an oral endotracheal tube (ETT) before operation because ETT is easy to handle during operation. If routine oral ETT insertion is difficult, we should seek other solutions. We report a successful conversion from tracheostomy tube to ETT in a
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Lung Transplantation in Pulmonary Arterial Hypertension: The Portuguese Experience Transplant. Proc. (IF 0.9) Pub Date : 2024-02-29 Margarida V. Matias, Zenito Cruz, Catarina Figueiredo, Catarina Moita, Miguel Roxo, João E. Reis, Ana Rita Costa, João Santos Silva, João Maciel Barbosa, Paulo Calvinho, Luísa Semedo
In patients with pulmonary arterial hypertension (PAH), refractory to medical therapy, lung transplantation emerges as an option. This study describes the outcomes of 8 PAH patients who underwent lung transplantation. A retrospective, single-center study was conducted among patients with PAH who underwent lung transplantation in our center. Patients had a median age of 46 years, with female sex predominance
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Outcomes of Kidney Transplantation Among COVID-19 Recovered Patients in a Single Transplant Center Transplant. Proc. (IF 0.9) Pub Date : 2024-02-27 Krystal C. Cervantes, Romina A. Danguilan, Mel-Hatra I. Arakama, Eric Chua, Cybele Lara R. Abad, Rose Marie O. Rosete-Liquete
The COVID-19 pandemic significantly lowered kidney transplantation (KT) rates worldwide, and studies regarding outcomes of patients who developed COVID-19 infection before KT are limited, especially in low to middle-income countries. To determine the 1-year graft and patient survival of kidney transplant recipients who recovered from COVID-19 infection before KT. We retrospectively reviewed all adult
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Intraoperative Normal Saline Administration and Acute Kidney Injury in Patients Undergoing Liver Transplantation Transplant. Proc. (IF 0.9) Pub Date : 2024-02-26 Ji-Yoon Jung, Jae-Woo Ju, Hyun-Kyu Yoon, Ho-Jin Lee, Won Ho Kim
Normal saline is still used in patients undergoing living donor liver transplantation (LDLT) with normonatremia. We investigated whether the normal saline administered during LDLT is associated with the increased risk of acute kidney injury (AKI) compared with the balanced crystalloids. We reviewed 1011 cases undergoing LDLT. The primary exposure variable was normal saline administered intraoperatively
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MASH Continues as a Significant Burden on Metabolic Health of Liver Recipients Transplant. Proc. (IF 0.9) Pub Date : 2024-02-24 Kinga Czarnecka, Paulina Czarnecka, Olga Tronina, Teresa Bączkowska, Magdalena Durlik
Metabolic complications are a recognized health concern in liver transplant recipients that result in inferior patient-reported outcomes. Patients with MASH are known to be disproportionately affected by metabolic diseases compared to other indications for transplantation. The aim of this study was to investigate the incidence of metabolic abnormalities in liver recipients with specific focus on differences
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Effect of Donors' Biliary Variation on Postoperative Biliary Complications in Living Donor Liver Transplantation: A Single-Center Observational Study in Vietnam Transplant. Proc. (IF 0.9) Pub Date : 2024-02-23 Chi Thanh Ho, Van Quang Vu, Kim Khue Dang, Hoan My Pham, Van Thanh Le, Trung Hieu Le, Hoang Ngoc Anh Nguyen, Van Linh Ho, Ngoc Tuan Vu, Cuong Thinh Nguyen
Our study aims to evaluate the biliary anatomy variation according to the Varotti classification and its correlation with surgical outcomes for both donors and recipients undergoing living donor liver transplants (LDLTs). A retrospective analysis of 150 LDLT cases performed at a single center in Vietnam with preoperative radiologic evaluations and intraoperative surgical assessments to identify biliary
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Arteriovenous Fistula Closure Using a Simple Ligation Technique After Kidney Transplantation Transplant. Proc. (IF 0.9) Pub Date : 2024-02-23 Toshihide Naganuma, Yoshikazu Kuroki, Tomoaki Iwai, Yoshiaki Takemoto, Junji Uchida
There are advantages and disadvantages with closure of an arteriovenous fistula (AVF) after kidney transplantation, but some cases require closure. The general procedure for closure is angioplasty with exposure of the anastomotic site, but this is often time-consuming and complicated. We have developed a simpler, less invasive, and shorter procedure for AVF closure, in which the anastomotic site itself
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A Novel Pre-Clinical Modeling of Massive Hemorrhagic Shock in Non-Human Primate: A Safe and Reproducible Method (Macaca fascicularis) Transplant. Proc. (IF 0.9) Pub Date : 2024-02-23 Eun Sung Jeong, Jae Berm Park, Sean Sang Woo Park, Kyo Won Lee, Dong Suk Kim, Yoon Jae Kim, Sung Joo Kim
Although non-human primates are the closest animals to humans to simulate physiological and metabolic responses, there is a paucity of primate hemorrhagic shock models that are standardized and reproducible. Herein, we describe a model that is a clinical replica of extreme class IV hemorrhagic shock with a step-by-step description of the procedure in cynomolgus macaque monkeys. The physiological changes
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Efficacy and Safety of Mycophenolate Mofetil In De Novo Renal Transplantation in a Retrospective Cohort of Transplant Recipients in Colombia—Esmitren Study Transplant. Proc. (IF 0.9) Pub Date : 2024-02-23 Jose Nelson Carvajal Quiroz, Juan Sebastián Gómez Villalobos, Juan Carlos Tobón Pereira
To describe and establish the efficacy and safety of Mycophenolate Mofetil (Micoflavin) in patients with de novo renal transplantation during one-year post-transplant follow-up. As secondary objectives, the behavior of mycophenolic acid (MPA) C0 levels in this population, the relationship between MPA levels and renal function of the grafts, the incidence of acute rejection, and the incidence of adverse
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Miliary Tuberculosis as Postmortem Diagnosis in Solid Organ Transplant Recipient: Case Report and Review of the Literature Transplant. Proc. (IF 0.9) Pub Date : 2024-02-22 Hanna Storoniak, Alicja Dębska-Ślizień
The diagnosis of tuberculosis (TB) in solid organ transplant (SOT) recipients presents challenges that may lead to treatment delay. These include atypical clinical presentations, increased likelihood of negative tuberculin skin test or/and interferon-gamma release assays, and negative sputum smear results despite active disease. The treatment poses challenges due to pharmacokinetic interactions, allograft-related
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Incidence and Risk Factors Associated With Chronic Kidney Disease After Liver Transplantation: A Review of a 20-Year Experience at a Single Center Transplant. Proc. (IF 0.9) Pub Date : 2024-02-22 Chutwichai Tovikkai, Jirasawet Sawetwanichakul, Prawat Kositamongkol, Prawej Mahawithitwong, Wethit Dumronggittigule, Pholasith Sangserestid, Charnwit Assawasirisin, Somchai Limsrichamrern, Yongyut Sirivatanauksorn
Chronic kidney disease (CKD) is one of the major complications after liver transplantation (LT), with a significant impact on patient outcomes. This study aims to investigate the incidence and risk factors of CKD in LT recipients at Siriraj Hospital over the past 20 years. There were 366 adult patients undergoing LT at Siriraj Hospital between January 2002 and December 2021. After excluding patients
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High-Dose Intravenous Immunoglobulin to Treat Anti-Thymocyte Globulin Induction–Related BK Virus and Cytomegalovirus Infection in Patients with ABO-Incompatible Kidney Transplantation Transplant. Proc. (IF 0.9) Pub Date : 2024-02-22 Jin Ho Lee, Heeryong Lee, Kipyo Kim, Seoung Woo Lee, Joon Ho Song, Seun Deuk Hwang
ABO-incompatible (ABOi) transplantation is a novel method transplantation method that carries a heightened risk of infection caused by the use of high immunosuppressant doses. This elevated risk is particularly concerning for viral infections, such as cytomegalovirus (CMV) and the BK virus (BKV) increases. Herein, we present a case where high-dose intravenous immunoglobulin (IVIG) was effective in
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Prediction of Early Kidney Transplant Graft Outcome: Insulin Resistance Index Transplant. Proc. (IF 0.9) Pub Date : 2024-02-22 Tsu-Chen Lin, Kuo-Jen Lin, Yang-Jen Chiang, Sheng-Hsien Chu, Kuan-Lin Liu, Chih-Te Lin, Pai-Yen Pan, Sy-Yuan Chen, Jui-Chung Wang, Hsu-Han Wang
New-onset diabetes after transplantation and increased insulin resistance have both been shown to affect graft performance and survival after kidney transplantation. Thus, we aimed to evaluate the predictive roles of different insulin resistance indices on early graft function in kidney transplant recipients. We conducted a retrospective analysis of non-diabetic patients who received kidney transplantation
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Effect of Plasmapheresis on the Efficacy of Rituximab in Antibody-Mediated Rejection Patients Transplant. Proc. (IF 0.9) Pub Date : 2024-02-20 Jin Ho Lee, Heeryong Lee, Kipyo Kim, Seoung Woo Lee, Joon Ho Song, Seun Deuk Hwang
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Monitoring Porcine Cytomegalovirus in Both Donors and Recipients is Crucial for Recipient's Survival in Pig-to-Cynomolgus Xenotransplantation Transplant. Proc. (IF 0.9) Pub Date : 2024-02-19 O Kyung Kwon, Eun Sung Jeong, Kyo Won Lee, Mi Ran Choi, Chung Hee Sonn, Bumrae Cho, Joohyun Shim, Kimyung Choi, Sung Joo Kim, Jae Berm Park
Xenotransplantation, particularly when involving pig donors, presents challenges related to the transmission of porcine cytomegalovirus (pCMV) and its potential impact on recipient outcomes. This study aimed to investigate the relationship between pCMV positivity in both donors and recipients and the survival time of cynomolgus monkey recipients after xenogeneic kidney transplantation. We conducted
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Effect of Induction Therapy Dose on Survival in Abo-Incompatible Kidney Transplantation: A Network Meta-Analysis Using Recent Data Transplant. Proc. (IF 0.9) Pub Date : 2024-02-19 Jin Ho Lee, Hee Ryong Lee, Seoung Woo Lee, Joon Ho Song, Seun Deuk Hwang
Rituximab is an essential induction immunosuppressant for ABO-incompatible kidney transplantation (KT) (ABOi-KT). However, studies on the optimal dose of rituximab are insufficient, and there are dosage differences between transplant centers and countries. Therefore, we conducted a study to determine the survival outcomes of patients receiving the most effective and safe dose of rituximab during ABOi-KT
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Autologous Blood Transfusion During Elective Surgery in a Candidate for Living Donor Transplantation: A Case Report Transplant. Proc. (IF 0.9) Pub Date : 2024-02-19 Magdalena Jankowska, Lin Akily, William Karlsen, Anna Jaźwińska, Hanna Suchanek, Alicja Dębska-Ślizień
Blood transfusions are risk factors for alloimmunization and unfavorable outcomes in solid organ transplant recipients. We propose the adoption of autologous blood transfusion (ABT) in transplant candidates and recipients referred to elective surgery. We present a case of a 45-year-old man with chronic kidney disease stage 5 due to polycystic kidney disease, who was qualified for a native kidney nephrectomy
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Challenges of Implementing a Human Multi-Tissue Bank in a Public Hospital in the Interior of São Paulo: Under the Light of the Quality Management System Transplant. Proc. (IF 0.9) Pub Date : 2024-02-19 Luiz Henrique de Freitas Filho, Cristina de Carvalho Silva Neves, Nilcilene Pinheiro Silva, Carlos Alexandre Curylofo Corsi, Evelyn Machado Cardoso, João Batista de Miranda, Gustavo Constantino de Campos
Human multi-tissue banks (HMTB) are important health institutions specialized in the capture, processing, and distribution of human tissues for transplants and research, aiming for safety and quality in the supply of their products, intended for reconstructive surgeries and injury repair, in addition to contributing to the advancement of research developed in regenerative medicine. This study aims
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Gaining Consensus Around Patient Risk Groups and Prognostic Profiles to Guide CMV Management Among Patients With Allogeneic Hematopoietic Stem Cell Transplant: Insights From a Delphi Panel With Hematopoietic Stem Cell Transplant Experts Transplant. Proc. (IF 0.9) Pub Date : 2024-02-18 Marlon Graf, Rifat Tuly, Priti Pednekar, Connie Wang, Katharine Batt
This study aimed to characterize patient risk groups and prognostic profiles to optimize clinical decision-making and guide appropriate medical cytomegalovirus (CMV) management among patients with allogeneic hematopoietic stem cell transplant (HSCT). Between 8/2021 and 2/2022, a 3-round modified Delphi study was conducted to generate consensus among 10 international experts in HSCT and infectious diseases
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The Effects of Busulfan on Xenogeneic Transplantation of Human Peripheral Blood Mononuclear Cells in Recipient Mice Transplant. Proc. (IF 0.9) Pub Date : 2024-02-16 Inseon Bak, Myeongjin Choi, Eunhye Yu, Kyeong-Won Yoo, Seo Yule Jeong, Jungyun Lee, Minseong Jo, Kyoung-Sik Moon, Dae-Yeul Yu
Humanized mouse models with engraftment of human peripheral blood mononuclear cells (PBMCs) or hematopoietic stem cells (HSCs) are effective tools for the study of human immunity. Busulfan has been used as a substitute for irradiation in human hematopoietic stem cell (HSC) transplantation models, but it has not been tested in human peripheral blood mononuclear cell (PBMC) transplantation models. This
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Arctigenin Induces Apoptosis in Melanoma Cells by Reducing the Expression of BCL-2 and VEGF Transplant. Proc. (IF 0.9) Pub Date : 2024-02-16 Yang Gao, He-peng Wang, Hai-fei Wang, Shi-meng Ma, Zi-wei Du, Jia Liu
To investigate the biological effects of arctigenin on B16-F10 melanoma cells in vitro and to explore its mechanism. B16-F10 melanoma cells in vitro were treated with the blank control solution and arctigenin solution of different concentrations, respectively. Cell proliferation and apoptosis were analyzed using the CCK-8 assay and cell loss assay, and the effect of arctigenin on melanoma cell proliferation
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Size Matching Deceased Donor Livers: The Tampa General Measurement System Transplant. Proc. (IF 0.9) Pub Date : 2024-02-16 Rachel Hogen, Thasya Smith, Bethany Jowers, Ambuj Kumar, Jacentha Buggs, Alejandro Chavarriaga, Ashish Singhal, Diego Reino, Vijay Subramanian, Kiran Dhanireddy
No reliable or standardized system exists for measuring the size of deceased donor livers to determine whether they will fit appropriately into intended recipients. This retrospective, single-center study evaluated the efficacy of Tampa General Hospital's size-matching protocol for consecutive, deceased donor liver transplantations between October 2021 and November 2022. Our protocol uses cross-sectional
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Impact of HLA Eplet Mismatch on De Novo Donor Specific Antibody Formation After Kidney Transplantation Transplant. Proc. (IF 0.9) Pub Date : 2024-02-16 Peerawit Yanyiam, Surasak Kantachuvesiri, Duangtawan Thammanichanond
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Open-Label Randomized Controlled Study of Ciprofloxacin vs Rifaximin as Neutropenia Prophylaxis in Allogeneic Hematopoietic Stem Cell Transplantation Transplant. Proc. (IF 0.9) Pub Date : 2024-02-16 Eleni Gavriilaki, Despina Mallouri, Evgenia Laspa, Anna Papakonstantinou, Andriana Lazaridou, Christos Varelas, Eirini Baldoumi, Angeliki Giannakopoulou, Christos Demosthenous, Anna Vardi, Zoi Bousiou, Ioannis Batsis, Georgia Gkioula, Achilles Anagnostopoulos, Ioanna Sakellari
Loss of microbiota diversity has been clearly associated with poor outcomes in the allogeneic hematopoietic stem cell transplantation setting. However, the choice of the optimal antibiotic prophylaxis during the pre-engraftment phase remains unclear. We designed a prospective randomized study to compare our standard-of-care neutropenia prophylaxis (ciprofloxacin) with rifaximin. We enrolled 38 consecutive
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Routine Kidney Graft Ultrasound After Elective Ureteric Stent Removal: Does it Help? Transplant. Proc. (IF 0.9) Pub Date : 2024-02-16 R. Haridian Sosa Barrios, Víctor Burguera Vion, Daniel Villa Hurtado, Elizabeth R. Viera Ramírez, Cristina Galeano Álvarez, Miriam Roncal Redín, Milagros Fernández Lucas, Maite E. Rivera Gorrín
Transplantation (KTx) is considered to be the best renal replacement therapy, and improving its outcomes remains a primary challenge. KTx ureteral stenting has been used to prevent urological complications, but there is no consensus on the timing of stent removal, and literature regarding routine ultrasonography after ureteric stent removal (RUSUS) to detect complications is lacking. Point-of-care
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Hypomagnesemia May Predict Better Survival and Reduced Nonrelapse Mortality in Allogeneic Hematopoietic Stem Cell Transplantation Recipients Transplant. Proc. (IF 0.9) Pub Date : 2024-02-16 Emine Merve Savaş, Zeynep Arzu Yegin, Münevver İrem Kök, Hande Tuğba Karayel, Zübeyde Nur Özkurt, Merve Nazlı Bozer, Melike Çamoğlu, Özlem Gülbahar
Magnesium (Mg) is an essential element that is required as a cofactor for many cellular reactions, including immunologic pathways. The aim of this study was to investigate the potential impact of serum Mg levels on allogeneic hematopoietic stem cell transplantation (alloHSCT) outcomes. Medical records of 340 alloHSCT recipients (median age: 45 [18-71] years; M/F: 210/130) were reviewed for this retrospective
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Sclerotherapy of the Post renal Transplant Lymphoceles: A Meta-Analysis Transplant. Proc. (IF 0.9) Pub Date : 2024-02-16 Ursula des Bordes, Timothy Hoang, Benjamin S. Dale, Ashwani Kumar Sharma
This study evaluated the effectiveness of sclerotherapy in treating lymphoceles after kidney transplantation, focusing on factors such as recurrence rates and procedural success. Retrospective studies using sclerotherapy as the only form of treatment for postrenal transplant lymphoceles were included. All studies used percutaneous transcatheter sclerotherapy as treatment, and the success rate of the
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Tacrolimus-Associated Terminal Ileitis After Kidney Transplantation, Mimicking Crohn Disease: A Case Report Transplant. Proc. (IF 0.9) Pub Date : 2024-02-16 Andrea Collini, Alessandra Ongaro, Evaldo Favi, Stefano Lazzi, Giorgio Micheletti, Giuliana Ruggieri
The onset of gastroduodenal ulcers is a frequent complication after transplantation, whereas cases of intestinal ulcers are sporadic and poorly described in the literature. A patient on immunosuppressive therapy with tacrolimus and mycophenolate mofetil after kidney transplant for immunoglobulin A–related glomerulonephritis developed symptoms compatible with Crohn disease 7 months after the transplant
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Results in Kidney Transplant Recipients from Living Donors 75 Years of Age or Older Transplant. Proc. (IF 0.9) Pub Date : 2024-02-16 Sevim Nuran Kuşlu Çiçek, Amil Huseynov, Murat Tuncer
The increasing age of patients receiving renal replacement therapy (RRT) in Turkey, coupled with a shortage of kidney donors, has led to longer waiting times for transplants and an escalation in mortality rates. This retrospective study aimed to assess the effect on transplant outcomes of accepting kidneys from donors ≥70 years of age, given the rising number of older patients in the population. In
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Determination of Risk Factors for Acute Kidney Injury In Orthotopic Cardiac Transplantation Transplant. Proc. (IF 0.9) Pub Date : 2024-02-15 Deniz Sarp Beyazpinar, Adem İlkay Diken, İzzet Hafez, Arif Okay Karslioğlu, Denizhan Akpinar, Murat Özkan, Hakkı Tankut Akay, Bahadır Gültekin, Atilla Sezgin
In this study, we try to determine risk factors for acute kidney injury in orthotopic cardiac transplantation patients. Between February 2003 and December 2022, all cardiac transplantation patients were retrospectively reviewed. Finally, 102 patients enrolled in this study. Demographic data, comorbidities, preoperative cardiac catheterization parameters, preoperative and postoperative blood test results
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Gene Ex Vivo Transduction Effects on Flap Survival and MicroRNAs Expression Analysis in Rat Allotransplantation Model Transplant. Proc. (IF 0.9) Pub Date : 2024-02-15 Yeonjin Jeong, Se Yeon Lee, Seok Kyung In, Miso Choi, Seokchan Eun
The lack of noninvasive biomarkers for graft rejection remains a challenge for the accurate monitoring of vascularized composite allotransplants. Viral vector-mediated gene transfer is a promising method for preventing graft rejection. In this study, we aimed to establish the expression profile of microRNAs (miRNAs) in skin flap allotransplantation, with or without gene transfer, and determine the
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Graft Protective and Intercellular Immunomodulatory Effects by Adoptive Transfer of an Agonistic Anti-BTLA mAb (3C10) Induced CD4+CD25+ Regulatory T Cells in Murine Cardiac Allograft Transplant Model Transplant. Proc. (IF 0.9) Pub Date : 2024-02-15 Hisanori Masaoka, Yasuto Yamamoto, Masateru Uchiyama, Kazuhito Iguchi, Masahiro Nakamura, Hideo Yagita, Tomohiro Imazuru, Tomoki Shimokawa
We demonstrated that an agonistic anti-B and T lymphocyte attenuator antibody (3C10) prolonged cardiac survival by inducing regulatory T cells (Treg). However, the mechanisms of immune tolerance in the recipients remained unclear. In this study, we investigated the graft-protective and intercellular immunomodulatory effects of adoptive transfer (AT) of 3C10-induced Tregs in a murine cardiac allograft
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Knowledge, Attitudes, Willingness, and Associated Factors to Organ Donation Among Intensive Care Unit Health Care Workers: Findings of a Cross-Sectional Study Transplant. Proc. (IF 0.9) Pub Date : 2024-02-15 Chu Gao, Yaqin Dai, Yufei Chai, Yingying Wang, Jiayun Wu, Mengyuan Ye, Xiaoyan Yi, Xiurong Jiang, Qin Jia
The lack of donor organs is a major barrier to the advancement of organ transplantation. This study aimed to understand the current status of knowledge, attitudes, and willingness to donate organs among intensive care unit (ICU) health care workers and analyzed the influencing factors to provide a scientific basis for improving the situation of a serious imbalance between the ratio of organ supply
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Haeme Oxygenas-1-Induced Liver Regeneration Protects Graft Against Small-for-Size Syndrome in Rats Transplant. Proc. (IF 0.9) Pub Date : 2024-02-15 Shiguo Xu, Bing Cheng, Bo Xie, Ning He
Haeme oxygenase (HO-1) affords protection against ischemia/reperfusion (I/R) injury; however, its effects on liver regeneration remain poorly explored. Our previous studies have shown that HO-1 is probably involved in liver regeneration, but its role in small-for-size syndrome (SFSS) is still unclear. Therefore, this study aims to investigate the effects of HO-1 on small-for-size graft (SFSG) and the
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Resource Use and Financial Impact of Oral Step-Down Therapy for Resistant Cytomegalovirus in Solid Organ Transplant Recipients Transplant. Proc. (IF 0.9) Pub Date : 2024-02-14 Hanna Kleiboeker, Jillian L. Descourouez, Lucas T. Schulz, Didier A. Mandelbrot, Jon S. Odorico, Christopher M. Saddler, Jeannina A. Smith, Margaret R. Jorgenson
Cytomegalovirus (CMV) infections are common opportunistic infections in solid organ transplants (SOT) with increased health care resource USE and costs. Costs are further increased with ganciclovir-resistance (GR). This study aimed to evaluate the real-world impact of conversion to oral step-down therapy on duration of foscarnet and hospital length of stay (LOS) for treatment of GR-CMV infections in
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Type A Aortic Dissection in Heart Transplantation Recipients in the United States Transplant. Proc. (IF 0.9) Pub Date : 2024-02-14 Yunda Wang, Joy Mohnot, Kanhua Yin, Niloo M. Edwards, Nikola Dobrilovic, Yong Zhan
Type A aortic dissection in heart transplantation recipients is rare and lethal, with limited research beyond case reports. This study aimed to analyze patient characteristics and clinical outcomes of this condition through a US national database. The National Inpatient Sample database (2002-2018) was used to identify all type A aortic dissection in heart transplantation recipients aged >18 years.
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Clinical Implications of Serum Mac-2 Binding Protein in Patients After Living Donor Liver Transplantation for Biliary Atresia Transplant. Proc. (IF 0.9) Pub Date : 2024-02-14 Takehisa Ueno, Koki Takase, Koichi Deguchi, Motonari Nomura, Miho Watanabe, Masafumi Kamiyama, Yuko Tazuke, Takeshi Kimura, Hiroomi Okuyama
Patients who undergo pediatric living donor liver transplantation (LDLT) sometimes develop graft fibrosis. Recently, Mac-2 binding protein glycosylation-modified isomer (M2BPGi) was developed as a new marker of hepatic fibrosis progression. We performed this study to examine the relationship between serum M2BPGi levels and liver histologic findings in patients after LDLT for biliary atresia. Patients
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Daprodustat for Post-Transplant Anemia in Renal Transplant Recipients Transplant. Proc. (IF 0.9) Pub Date : 2024-02-13 Yuichi Machida, Tomoaki Iwai, Kazuya Kabei, Toshihide Naganuma, Junji Uchida
Daprodustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, has been reported to be effective in treating conservative renal failure and renal anemia in patients undergoing dialysis. However, its effects on post-transplant anemia have not yet been reported. This study aimed to determine whether daprodustat may be a useful treatment for post-transplant anemia. Excluding 5 cases in which the
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Effects of Livact Granule on Liver Function Recovery After Donor Right Hemi-Hepatectomy Transplant. Proc. (IF 0.9) Pub Date : 2024-02-13 Gun Hyung Na, Ho Joong Choi, Jin Ha Chun, Yoonyoung Choi, Sung Eun Park, Tae Ho Hong, Young Kyoung You
Living donor liver transplantation (LDLT) is currently widespread due to organ shortage. Because LDLT is a high-risk surgery for the donor, donor safety becomes an important issue. In adult LDLT, right lobe grafts are usually used, posing a greater risk to the donor than a left lobe. Reports have demonstrated that branched-chain amino acids help patients recover after hepatectomy. This study aimed
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Proposal of a Network System to Solve the Problem of Small Volume in Liver Transplantation; Catholic Medical Center Network Transplant. Proc. (IF 0.9) Pub Date : 2024-02-13 Yoonyoung Choi, Ho Joong Choi, Haneol Park, Yoonkyung Woo, Jinha Chun, Young Chul Yoon, Tae Yun Lee, Gun Hyung Na, Chang Ho Seo, Jae Hyun Han, Jung Hyun Park, Eui Soo Han, Tae Ho Hong, Young Kyoung You
Liver transplantation (LT) is a complex and demanding procedure associated with significant perioperative challenges and risks. Concerns have arisen regarding LT outcomes in low-volume centers. We implemented an integrated training and surgical team network to address these concerns within the Catholic Medical Center (CMC) network. This study presents a comprehensive review of our 9-year LT experience
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Renal Artery Stenosis in Living Donor Kidney Transplantation: A Rare Cause of “Flash Edema” Transplant. Proc. (IF 0.9) Pub Date : 2024-02-13 Bruno Fraga Dias, Roberto Marques, Vitória Faria, Patrícia Domingues, Catarina Ribeiro, José Silvano, Jorge Malheiro, Manuela Almeida, Sofia Pedroso, La Salete Martins
Transplant renal artery stenosis (TRAS) is a well-recognized vascular complication after kidney transplantation, with an incidence ranging from 1% to 23%. TRAS often presents with clinical features such as refractory hypertension, de novo hypertension, allograft dysfunction, and the presence of a bruit over the graft. A rare manifestation of TRAS is flash pulmonary edema. Here, we present a case of
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Histochemical Identification of Motor Fascicles Using Cholinesterase Staining in Rats Using a Mixed Nerve Model Transplant. Proc. (IF 0.9) Pub Date : 2024-02-13 Yeonjin Jeong, Se Yeon Lee, Miso Choi, Seokchan Eun
Inappropriate matching of motor and sensory fibers after nerve repair or grafting can lead to nerve recovery failure. Identifying the motor and sensory fascicles enables surgeons to match them accurately and correctly align nerve stumps, which is crucial for neural regeneration. Very few methods have been reported to differentiate between the sensory and motor nerve fascicles, and the replicability
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Comparison of Optical Trocar Access Versus Veress Needle Insertion Technique for Peritoneal Entry in Laparoscopic Donor Nephrectomy Transplant. Proc. (IF 0.9) Pub Date : 2024-02-13 Askin Eroglu, Rahmi Gokhan Ekin
Nearly half of all complications in laparoscopic surgery occur at the intraperitoneal access. We compared direct optical entry (DOE) with Veress needle entry (VNE) in terms of abdominal entry time and entry-associated complications in patients who underwent laparoscopic donor nephrectomy (LDN). Between June 2010 and July 2023, data from 813 patients who underwent LDN were analyzed. Age, male-to-female
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Technical Considerations in the Pig-To-Human Kidney Xenotransplant: A Historical Perspective Transplant. Proc. (IF 0.9) Pub Date : 2024-02-13 Dai Dao Nghiem
As the limited supply of human donor organs remains the greatest barrier to renal transplantation, porcine renal xenografts have the potential to reduce the organ shortage. Recent attempts at using genetically engineered porcine renal xenografts have met with technical and functional problems. It is theorized that if transplantation of the en bloc kidneys had been performed: (1) the double nephron