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Transfusion and Mortality in Acute Care Surgical Patients in Malawi: A Propensity-Matched Analysis J. Surg. Res. (IF 2.2) Pub Date : 2024-03-14 Selena J. An MD MSPH MA, Natasha Ngwira MBBS FCS ECSA, Dylane Davis BA, Jared Gallaher MD MPH, Anthony Charles MD MPH
Information on transfusion-associated outcomes is limited in sub-Saharan Africa. We sought to characterize predictors of mortality in transfused patients with acute care surgical conditions in Malawi. We performed a retrospective propensity-matched analysis of patients with acute care surgical conditions at Kamuzu Central Hospital in Malawi from 2013 to 2021. We compared outcomes between patients who
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The Characterization of Violent Deaths Among Asian and Pacific Islander Americans J. Surg. Res. (IF 2.2) Pub Date : 2024-03-14 Wesley Tran MD, Madeline B. Thomas MD, Denise Garofalo MD, Monica Patten MD, Rachel Graham MD MPH, Josue Estrella MD, Kaitlyn Dickinson MS, Heather Carmichael MD, Catherine G. Velopulos MD MHS, Quintin W.O. Myers PhD
Health disparities in the Asian and Pacific Islander Americans (APIAs) community have not been well described, unlike non-Hispanic Black and Hispanic communities. However, there has been a rise in violence against the APIA community. This study explores and characterizes violent death by incident (e.g., homicide, suicide), weapon (e.g., firearm, strangulation), and location types among APIAs as they
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To Resect or Not to Resect: A Nationwide Comparison of Management of Sigmoid Volvulus J. Surg. Res. (IF 2.2) Pub Date : 2024-03-13 Wardah Rafaqat MD, Emanuele Lagazzi MD, Shannon McChesney MD, Michael C. Smith MD, Mujeeb UrRahman MD, Hanjoo Lee MD, Michael P. DeWane MD, Aimal Khan MD
Despite the high recurrence rate of sigmoid volvulus, there is reluctance to perform a prophylactic colectomy in frail patients due to the operation's perceived risks. We used a nationally representative database to compare risk of recurrence in patients undergoing a prophylactic colectomy endoscopic detorsion alone. We performed a retrospective cohort study using the National Readmission Database
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General Surgery Resident Participation in a Mandatory Wellness Program: Six Years Later J. Surg. Res. (IF 2.2) Pub Date : 2024-03-08 Aleezay Haider MD, Jessica Sullivan MD, Elizabeth Lawrence MD, John C. Russell MD FACS, Jasmeet Paul MD FACS, Alissa Greenbaum MD
Following the approval of a resident-created physician wellness program in 2016, an initial survey demonstrated majority support for the implementation of a mandatory curriculum. The purpose of this study is to survey surgical residents about the wellness curriculum six years after implementation and re-evaluate preference for mandatory participation. In 2016, the CORE7 Wellness Program didactic sessions
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COVID-19 and Mortality in the Global Surgical Population: A Systematic Review and Meta-Analysis J. Surg. Res. (IF 2.2) Pub Date : 2024-03-08 Prisca Obidike MD, Allison Chang MD, Olivia Calisi MD MEd, Jungeun J. Lee BS, Paddy Ssentongo MD PhD MPH, Anna E. Ssentongo DrPH MPH, John S. Oh MD
To date, no systematic review or meta-analysis has comprehensively estimated the risk of mortality by surgery type on an international scale. We aim to delineate the risk of mortality in patients with COVID-19 who undergo surgery. PubMed (MEDLINE), Scopus, OVID, the World Health Organization Global Literature on Coronavirus Disease, and Corona–Central databases were searched from December 2019 through
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Resveratrol Promotes Diabetic Wound Healing by Inhibiting Notch Pathway J. Surg. Res. (IF 2.2) Pub Date : 2024-03-05 Yu Liu MM, Biyao Zheng MM, Hao Zheng MM, Gang Xu MM, Hai Jiang MM
Diabetic foot ulcer (DFU) is a severe complication that threatens the daily lives of patients with diabetes and represents a serious challenge to the global health system. Considering that impaired wound healing is the leading cause of DFU, exploring the mechanism of diabetic wound healing is beneficial for improving DFU treatment. Resveratrol (RES) is a native polyphenol with various pharmacological
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Assessing the Modified Frailty Index and Post-Operative Outcomes in Adhesive Small Bowel Obstruction: A Retrospective Cohort Study J. Surg. Res. (IF 2.2) Pub Date : 2024-03-05 Gaurav Talwar MD BSc, Tyler McKechnie MD MSc, Janhavi Patel MD BMSc, Reva Qiu MD BSc, Kathy Wu MD HBA, Yung Lee MD MPH, Dennis Hong MD MSc FRCSC, Aristithes Doumouras MD MPH FRCSC, Jessica Bogach MD MSc FRCSC, Cagla Eskicioglu MD MSc FRCSC FASCRS
Studies identifying predictors of postoperative outcomes in adhesive small bowel obstruction are limited. This study investigates the efficacy of the modified frailty index (mFI)to predict postoperative morbidity and mortality among patients undergoing surgery for adhesive small bowel obstruction. A multicentre retrospective cohort study including patients undergoing surgery for adhesive small bowel
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A Multi-Institutional Study Comparing Stoma Location in Neonates With Intestinal Perforation J. Surg. Res. (IF 2.2) Pub Date : 2024-03-02 Stephanie Y. Chen MD, Gabriella Grisotti MD, Shale J. Mack BS, Ashley E. Walther MD, Rachel L. Chapman MD, Richard A. Falcone Jr. MD MPH, Eugene S. Kim MD
Neonates with intestinal perforation often require laparotomy and intestinal stoma creation, with the stoma placed in either the laparotomy incision or a separate site. We aimed to investigate if stoma location is associated with risk of postoperative wound complications. A multi-institutional retrospective review was performed for neonates ≤3 mo who underwent emergent laparotomy and intestinal stoma
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Cost and Late Hospital Care of Publicly Insured Children After Appendectomy J. Surg. Res. (IF 2.2) Pub Date : 2024-03-01 Kenneth A. Michelson MD MPH, Brian T. Bucher MD MPH, Mark I. Neuman MD MPH
Immediate complications of appendicitis are common, but the prevalence of long-term complications is uncertain. We studied all publicly-insured children in the US with uncomplicated or complicated appendicitis in 2018-2019 using administrative claims. The main outcome was late hospital care defined as hospitalization or abdominal procedure within 180 d of an appendicitis discharge, excluding interval
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Systematic Literature Review of Health-Related Quality-of-Life Measures for Caregivers of Older Adult Trauma Patients J. Surg. Res. (IF 2.2) Pub Date : 2024-03-01 Krista Haines DO MA, Stephanie T. Lumpkin MD, Braylee Grisel BS, Kavneet Kaur BS, Sarah Cantrell MLIS, Jennifer Freeman MD MPH, Todd Tripoli BS, Scott Gallagher MD, Suresh Agarwal MD, Christopher E. Cox MD MPH, Kenneth Schmader MD, Bryce B. Reeve PhD
As the older adult population increases, hospitals treat more older adults with injuries. After leaving, these patients suffer from decreased mobility and independence, relying on care from others. Family members often assume this responsibility, mostly informally and unpaid. Caregivers of other older adult populations have increased stress and decreased caregiver-related quality of life (CRQoL). Validated
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Pooled Analysis of Trauma Centers Better Predicts Risk Factors for Firearm Violence Reinjury J. Surg. Res. (IF 2.2) Pub Date : 2024-02-23 Derek C. Lumbard, Michaela A. West, Irena R. Cich, Salma Hassan, Sruthi Shankar, Rachel M. Nygaard
Many trauma centers use the first firearm injury admission as a reachable moment to mitigate reinjury. Understanding repeat firearm violence can be difficult in metropolitan areas with multiple trauma centers and laws that prohibit sharing private health information across health systems. We hypothesized that risk factors for repeat firearm violence could be better understood using pooled data from
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Letter Regarding: “Prophylactic Central Neck Dissection Based on Preoperative Imaging and Intraoperative Surgeon’s Palpation versus Total Thyroidectomy Alone for Papillary Thyroid Cancer” J. Surg. Res. (IF 2.2) Pub Date : 2024-02-21 Srishti Sharma, Deepak Kumar, Prashant Kumar Singh, Chandan Kumar Jha
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Neighborhood Socioeconomic Status and Readmission in Acute Type A Aortic Dissection Repair J. Surg. Res. (IF 2.2) Pub Date : 2024-02-20 Tom Liu, Paul J. Devlin, Beth Whippo, Patricia Vassallo, Andrew Hoel, Duc Thinh Pham, Douglas R. Johnston, Sukit Chris Malaisrie, Christopher K. Mehta
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No Association of Blood Alcohol Concentration on Burn Patient Outcomes J. Surg. Res. (IF 2.2) Pub Date : 2024-02-19 Justin Bria, Awni Shahait, Luz Nagle, Michael White, Samantha Tarras
Alcohol abuse is common among burn patients. Burn patients under the influence of alcohol are at risk for developing organ failure, prolonged hospital duration, and increased intensive care unit (ICU) resources. Our study aims to analyze the association between presenting alcohol levels and the outcomes of burn patients. A retrospective analysis of admitted burn patients was performed from 2016 to
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Stop the Bleed in the Era of Virtual Learning: A Novel Strategy for Remote Teaching and Evaluation J. Surg. Res. (IF 2.2) Pub Date : 2024-02-19 Fatemeh P. Parvin-Nejad, Geetasravya Vegunta, Giovanna Mele, Ziad C. Sifri
Traumatic hemorrhage is a leading cause of preventable mortality worldwide. The Stop the Bleed (STB) course was developed to equip layperson bystanders with basic bleeding control knowledge and skills. However, large in-person courses have been disrupted due to COVID-19. The aim of this study was to determine the feasibility of teaching and evaluating STB skills through remote video-based instruction
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Pediatric Trauma Care Disparities: Association of Race and Sex With High Acuity Trauma Hospital Admissions J. Surg. Res. (IF 2.2) Pub Date : 2024-02-19 Prerna Ladha, Caleb W. Curry, Avanti Badrinathan, Marisa R. Imbroane, Rasika V. Bhamre, John J. Como, Esther S. Tseng, Vanessa P. Ho
For adult trauma patients, the likelihood of receiving treatment at a hospital properly equipped for trauma care can vary by race and sex. This study examines whether a pediatric patient's race/ethnicity and sex are associated with treatment at a high acuity trauma hospital (HATH). Using the 2017 National Inpatient Sample, we identified pediatric trauma patients ( ≤16 y) using International Classification
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Immune Landscape of Epstein–Barr Virus–Associated Gastric Cancer: Analysis From a Western Academic Institution J. Surg. Res. (IF 2.2) Pub Date : 2024-02-17 Elliott J. Yee, Danielle Gilbert, Jeffrey Kaplan, Linda van Dyk, Sunnie S. Kim, Leslie Berg, Eric Clambey, Sachin Wani, Martin D. McCarter, Camille L. Stewart
Epstein–Barr virus–associated gastric cancer (EBVaGC) may be a meaningful biomarker for potential benefit from immunotherapy. Further investigation is needed to characterize the immune landscape of EBVaGC. We assessed our institutional frequency of surgically treated EBVaGC and analyzed the immunologic biomarker profile and tumor-infiltrating lymphocyte (TIL) phenotypes of a series of EBVaGC compared
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Is REBOA the Last Card to Control a Massive Gastrointestinal Bleeding? J. Surg. Res. (IF 2.2) Pub Date : 2024-02-17 Fernando Rodríguez-Holguín, Alexander Salcedo, Philip Leib, Yaset Caicedo, José Julián Serna, Luis Toro, Sandra Carvajal, Manolo Riascos, Michael W. Parra, Alberto García, Carlos A. Ordoñez
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a potential tool for the management of massive gastrointestinal bleeding (MGB). This study aims to describe the experience of the use of REBOA as adjunctive therapy in patients with MGB and to evaluate its effectiveness. Serial cases of patients with hemorrhagic shock secondary to MGB in whom REBOA was placed were collected. Patient
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Geriatric Assessment in Colorectal Surgery: A Systematic Review J. Surg. Res. (IF 2.2) Pub Date : 2024-02-16 Christy E. Cauley, Aubrey Samost-Williams, Lisa Philpotts, Mary Brindle, Zara Cooper, Christine S. Ritchie
The prevalence of colorectal surgery among older adults is expected to rise due to the aging population. Geriatric conditions (e.g., frailty) are risk factors for poor surgical outcomes. The goal of this systematic review is to examine how current literature describes geriatric assessment interventions in colorectal surgery and associated outcomes. Systematic searches of Ovid MEDLINE, Cochrane Library
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Assessing the Readability of Clinical Trial Consent Forms for Surgical Specialties J. Surg. Res. (IF 2.2) Pub Date : 2024-02-16 Amir H. Karimi, Maura R. Guyler, Christian J. Hecht, Robert J. Burkhart, Alexander J. Acuña, Atul F. Kamath
To evaluate the readability of surgical clinical trial consent forms and compare readability across surgical specialties. We conducted a cross-sectional analysis of surgical clinical trial consent forms available on ClinicalTrials.gov to quantitatively evaluate readability, word count, and length variations among different specialties. The analysis was performed between November 2022 and January 2023
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A Retrospective Analysis of Surgical Acuity & Procedure Volume Before & During the COVID-19 Pandemic J. Surg. Res. (IF 2.2) Pub Date : 2024-02-15 Xavier P. Fowler, Brianna Krafcik, Ming Cai, Barbara Gladders, Emily Spangler, Kayla O. Moore, Sandra Wong, David Stone, David Soybel, Jesse Columbo, Philip P. Goodney, Louise Davies
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Cryoablation Reduces Opioid Consumption and Length of Stay After Pulmonary Metastasectomy J. Surg. Res. (IF 2.2) Pub Date : 2024-02-15 Charbel Chidiac, Kristin Wharton, Alejandro V. Garcia, Daniel S. Rhee
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Comparing Robotic, Thoracoscopic, and Open Segmentectomy: A National Cancer Database Analysis J. Surg. Res. (IF 2.2) Pub Date : 2024-02-15 Raul Caso, Thomas J. Watson, Eshetu Tefera, Robert Cerfolio, Abbas E. Abbas, John F. Lazar, Marc Margolis, Ann E. Hwalek, Puja Gaur Khaitan
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Evaluating Global Surgery Partnerships From Low and Middle Income Country Perspectives J. Surg. Res. (IF 2.2) Pub Date : 2024-02-15 Kelsi N. Krakauer, Lye-Yeng Wong, Joseph Tobias, Olubunmi Majekodunmi, Darius Balumuka, Kali Bravo, Emmanuel Ameh, Samuel Finlayson, Benedict Nwomeh, Ziad Sifri, Anthony Charles, Sanjay Krishnaswami
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Limited English Proficiency Is Not Associated With Poor Postoperative Outcomes or Follow-up Rates in Patients Undergoing Breast Reduction Mammoplasty – A Single Institution Retrospective Cohort Study J. Surg. Res. (IF 2.2) Pub Date : 2024-02-15 Wang Fei, Shah Jinesh, Greige Nicolas, Yi Joseph, Ni Jason, Joseph A. Ricci
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Desmopressin, Misoprostol, nor Carboprost Affect Platelet Aggregability Following Traumatic Brain Injury and Aspirin J. Surg. Res. (IF 2.2) Pub Date : 2024-02-14 Matthew R. Baucom, Adam D. Price, Nicholas Weissman, Lisa England, Rebecca M. Schuster, Timothy A. Pritts, Michael D. Goodman
Desmopressin (DDAVP) has been utilized clinically in patients taking aspirin (ASA) to improve drug-induced platelet dysfunction. Misoprostol and carboprost, prostaglandin analogs commonly used for postpartum hemorrhage, may also induce platelet aggregation. The aim of this study was to determine the effects of DDAVP, misoprostol, and carboprost administration on platelet aggregability following traumatic
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Documentation of Trauma-Informed Care Elements for Young People Hospitalized After Assault Trauma J. Surg. Res. (IF 2.2) Pub Date : 2024-02-14 Insia Zufer, Rebecca L. Fix, Elizabeth Stone, Rachel Cane, Joseph V. Sakran, Isam Nasr, Katherine Hoops
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The First Generation of Asian American Pediatric Surgical Trainees in North America J. Surg. Res. (IF 2.2) Pub Date : 2024-02-14 Kenneth W. Gow, XiaoYue Han, Eugene S. Kim, Meera Kotagal, Grace Mak, Sanjay Krishnaswami
Pediatric surgical trainees come from diverse races and ethnicities. However, Asian-Americans (AAs) including West, South, and East Asians may represent a unique group of individuals. We sought to identify any unique challenges and experiences. Pediatric surgical trainees were identified from, “” and Celebrating 50 Years: Canadian Association of Paediatric Surgeons/Association Canadienne de Chirurgie
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Anatomy Versus Biology: What Guides Chemotherapy Decisions in Older Patients With Breast Cancer? J. Surg. Res. (IF 2.2) Pub Date : 2024-02-14 Sydney M. Record, Samantha M. Thomas, William M. Tian, Astrid Botty van den Bruele, Akiko Chiba, Gayle DiLalla, Maggie L. DiNome, Gretchen Kimmick, Laura H. Rosenberger, Hannah E. Woriax, E. Shelley Hwang, Jennifer K. Plichta
With the increasing utilization of genomic assays, such as the Oncotype DX recurrence score (RS), the relevance of anatomic staging has been questioned for select older patients with breast cancer. We sought to evaluate differences in chemotherapy receipt and/or survival among older patients based on RS and sentinel lymph node biopsy (SLNB) receipt/result. Patients aged ≥ 65 diagnosed with pT1-2/cN0/M0
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Evaluating the Effectiveness of Trauma-Informed Care Frameworks in Provider Education and the Care of Traumatized Patients J. Surg. Res. (IF 2.2) Pub Date : 2024-02-13 Brian Chin, Quratulain Amin, Nickolas Hernandez, D-Dre Wright, Muhammad Usman Awan, Donald Plumley, Tracy Zito, Adel Elkbuli
Trauma-informed care (TIC) spans many different health care fields and is essential in promoting the well-being and recovery of traumatized individuals. This review aims to assess the efficacy of TIC frameworks in both educating providers and enhancing care for adult and pediatric patients. A literature search was conducted using PubMed, EMBASE, Proquest, Cochrane, and Google Scholar to identify relevant
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Augmented Reality Guided Laparoscopic Liver Resection: A Phantom Study With Intraparenchymal Tumors J. Surg. Res. (IF 2.2) Pub Date : 2024-02-13 Mathieu Ribeiro, Yamid Espinel, Navid Rabbani, Bruno Pereira, Adrien Bartoli, Emmanuel Buc
Augmented reality (AR) in laparoscopic liver resection (LLR) can improve intrahepatic navigation by creating a virtual liver transparency. Our team has recently developed Hepataug, an AR software that projects the invisible intrahepatic tumors onto the laparoscopic images and allows the surgeon to localize them precisely. However, the accuracy of registration according to the location and size of the
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Associations Between Program Doximity Reputation Rank and Well-Being in General Surgery Residents J. Surg. Res. (IF 2.2) Pub Date : 2024-02-12 Tanaz Naterwala, Matthew C. Chia, Rhami Khorfan, Elaine O. Cheung, Joshua S. Eng, Yue-Yung Hu, Karl Y. Bilimoria
Burnout and mistreatment are prevalent among surgical residents with considerable program-level variation. Applicants consider “program reputation,” among other factors, when ranking programs. Although highly subjective, the only available measure of program reputation is from a physician survey by Doximity. It is unknown how program reputation is associated with resident well-being and mistreatment
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Luminal Delivery of Pectin-Modified Oxygen Microbubbles Mitigates Rodent Experimental Intestinal Ischemia J. Surg. Res. (IF 2.2) Pub Date : 2024-02-12 Mathew Morreau, Ernest Cheah, Sachin Thakur, Jiwon Hong, Anthony Hickey, Anthony Phillips, John Windsor
Ischemic gut injury is common in the intensive care unit, impairs gut barrier function, and contributes to multiorgan dysfunction. One novel intervention to mitigate ischemic gut injury is the direct luminal delivery of oxygen microbubbles (OMB). Formulations of OMB can be modified to control the rate of oxygen delivery. This project examined whether luminal delivery of pectin-modified OMB (OMBp5)
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Perioperative Outcomes After Adrenalectomy for Secondary Adrenal Malignancy J. Surg. Res. (IF 2.2) Pub Date : 2024-02-09 Rebecca L. Green, Terry P. Gao, Lindsay E. Kuo
The risk of adverse outcomes after adrenal metastasectomy is not well defined. Knowledge of these risks is essential to guide patient counseling. The 2015-2020 National Surgical Quality Improvement Program datasets were combined. Patients who underwent adrenalectomy for secondary adrenal malignancy (SM) and benign nonfunctional (BNF) adrenal neoplasms were identified; BNF neoplasms were chosen as a
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Timing and Location of Venous Thromboembolisms After Surgery for Inflammatory Bowel Disease J. Surg. Res. (IF 2.2) Pub Date : 2024-02-09 Nicholas P. McKenna, Katherine A. Bews, Kevin T. Behm, Kellie L. Mathis, Robert R. Cima, Elizabeth B. Habermann
Patients with inflammatory bowel disease are reported to be at elevated risk for postoperative venous thromboembolism (VTE). The rate and location of these VTE complications is unclear. Patients with ulcerative colitis (UC) or Crohn’s disease (CD) undergoing intestinal operations between January 2006 and March 2021 were identified from the medical record at a single institution. The overall incidence
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Effectiveness of Stitch With Pledget to Prevent Prolonged Air Leak in Thoracoscopic Lung Resection J. Surg. Res. (IF 2.2) Pub Date : 2024-02-09 Toshiki Tanaka, Junichi Murakami, Sota Yoshimine, Naohiro Yamamoto, Kazuhiro Ueda, Ryo Suzuki, Hiroshi Kurazumi, Kimikazu Hamano
We previously demonstrated the usefulness of combining stitching with covering to seal alveolar air leaks in an animal model. This study aimed to clarify the effectiveness and feasibility of this sealing method in the clinical setting. Data of 493 patients who underwent thoracoscopic anatomical resection between 2013 and 2020 for lung cancer were retrospectively reviewed. Prolonged air leak was defined
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Which Localizing Strategy is the Most Cost-Effective in Reoperative Primary Hyperparathyroidism? J. Surg. Res. (IF 2.2) Pub Date : 2024-02-09 Victor Gazivoda, Katherine M. Prioli, Albert C. Li, Laura Pizzi, Amanda M. Laird, Toni Beninato
2%-10% of patients with primary hyperparathyroidism (PHPT) who undergo parathyroidectomy develop persistent/recurrent disease. The aim of this study was to determine which preoperative localization method is most cost-effective in reoperative PHPT. Clinical decision analytic models comparing cost-effectiveness of localizing studies in reoperative PHPT were constructed using TreeAge Pro. Cost and probability
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Hospital-Wide Adherence to Postsurgical Opioid Prescribing Guidelines: A Retrospective Cohort Study J. Surg. Res. (IF 2.2) Pub Date : 2024-02-09 Jacob P. Siebenmorgen, Johnathan H. Goree, Eric R. Siegel, Sarah E. Norman, Benjamin M. Stronach, Jeffrey B. Stambough, Simon C. Mears
Lowering opioid prescription doses and quantity decreases the risk of chronic opioid usage. A tool was inserted into the brief operative note for the surgeon to assess the severity of pain associated with the procedure. We studied surgeon adherence to current opioid-prescribing recommendations. Retrospective cohort study with 5486 patients were included in the study population. Each patient's prescription
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The Retained Surgical Items Risk Assessment Scale: Development and Psychometric Characteristics J. Surg. Res. (IF 2.2) Pub Date : 2024-02-09 Hamide Nur Erkan, Özlem Soyer Er
Retained surgical items in operating rooms (ORs) continue to contribute significantly to medical errors. The first step in addressing the problem of retained surgical items is to identify the main risk factors. Identification of risk factors can impact OR standards and reduce such errors. The research included 270 participants. The data of the study were collected with the Sociodemographic and Clinical
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Kidney Transplantation Anastomotic Time Is Jointly Associated With Resident and Attending Experience J. Surg. Res. (IF 2.2) Pub Date : 2024-02-08 Caroline M. Godfrey, Laura A. Rausch, Irene D. Feurer, Scott A. Rega, David Shaffer, Bernard DuBray, Laura Hickman, Kyla Terhune, Rachel Forbes
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Development of a Predictive Nomogram for Circumferential Resection Margin in Rectal Cancer Surgery J. Surg. Res. (IF 2.2) Pub Date : 2024-02-08 Megan Shroder, Molly M. Ford, Fei Ye, Zhiguo Zhao, Aimal Khan, Shannon McChesney, M. Benjamin Hopkins, Alexander T. Hawkins
Circumferential resection margin (CRM) is a key quality metric and predictor of oncologic outcomes and overall survival following surgery for rectal cancer. We aimed to develop a nomogram to identify patients at risk for a positive CRM in the preoperative setting. We performed a retrospective evaluation of the National Cancer Database from 2010 to 2014 for patients with clinical stage I-III rectal
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Assessing Adequacy: A Meta-Analysis of Rapid Onsite Evaluation of Thyroid Nodules J. Surg. Res. (IF 2.2) Pub Date : 2024-02-07 Peter P. Issa, Christina McCarthy, Mohammad Hussein, Aaron L. Albuck, Essam Emad, Mohamed Shama, Krzysztof Moroz, Eman Toraih, Emad Kandil
Fine-needle aspiration (FNA) is the standard form of preoperative evaluation of thyroid nodule cytological status. A significant number FNAs are classified as inadequate for interpretation, requiring a repeat FNA which is potentially avoidable, costly, and delays treatment. To address these concerns and maximize first-time FNA adequacy, rapid onsite evaluation (ROSE) of FNA specimens was introduced
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Large-Diameter Fenestrated Endograft Repair of Abdominal Aortic Aneurysms Is Not Associated With Medium-Term Outcomes J. Surg. Res. (IF 2.2) Pub Date : 2024-02-07 Issam Koleilat, Varun Dalmia, Paola Batarseh, Anvit Rai, Matthew Carnevale, John Phair, Jeff Indes
Recent data suggests that infrarenal abdominal aortic aneurysm (AAA) endovascular repair (EVAR) with large diameter grafts (LGs) may have a higher risk of endoleak and reintervention. However, this has not been studied extensively for fenestrated endovascular aneurysm repair (fEVAR). We, therefore, sought to evaluate the outcomes of patients undergoing fEVAR with large-diameter endografts. Patients
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The 5-Factor Modified Frailty Index is a Concise and Effective Predictor of 30-day Adverse Outcomes in Carotid Endarterectomy J. Surg. Res. (IF 2.2) Pub Date : 2024-02-07 Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen
Frailty is a clinically identifiable condition characterized by heightened vulnerability. The 5-item Modified Frailty Index provides a concise calculation of frailty that has proven effective in predicting adverse perioperative outcomes across a variety of surgical disciplines. However, there is a paucity of research examining the validity of 11-item Modified Frailty Index (mFI-5) in carotid endarterectomy
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Just Say NO: Inhaled Nitric Oxide Effect on Respiratory Parameters Following Traumatic Brain Injury in Humans and a Porcine Model J. Surg. Res. (IF 2.2) Pub Date : 2024-02-06 Adam D. Price, Matthew R. Baucom, Thomas C. Blakeman, Maia Smith, Dina Gomaa, Chelsea Caskey, Timothy Pritts, Richard Strilka, Richard D. Branson, Michael D. Goodman
The mechanism of post-traumatic brain injury (TBI) hypoxemia involves ventilation/perfusion mismatch and loss of pulmonary hypoxic vasoconstriction. Inhaled nitric oxide (iNO) has been studied as an adjunct treatment to avoid the use of high positive end-expiratory pressure and inspired oxygen in treatment-refractory hypoxia. We hypothesized that iNO treatment following TBI would improve systemic and
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The Intersection of Family Planning and Perception of Career Advancement in General Surgery J. Surg. Res. (IF 2.2) Pub Date : 2024-02-06 Ashaka Patel, Claire A. Wilson, Jacob Davidson, Jennifer Y. Lam, M. Elise Graham, Natashia M. Seemann
Women in surgery face unique challenges, particularly as it relates to family planning, parental leave, infant feeding, and career advancement. This study highlights disparities in present day general surgery training to tackle longstanding gender inequities. An open, anonymous online survey was distributed to Canadian residents, fellows, and practicing general surgeons through the Canadian Association
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Modern Trends for Primary Hyperparathyroidism: Intervening on Less Biochemically Severe Disease J. Surg. Res. (IF 2.2) Pub Date : 2024-02-06 Lauren N. Krumeich, Angelica Santos, Douglas L. Fraker, Rachel R. Kelz, Heather Wachtel
Primary hyperparathyroidism (PHPT) is defined by autonomous parathyroid hormone secretion, which has broad physiologic effects. Parathyroidectomy is the only cure and is recommended for patients demonstrating symptomatic disease and/or end organ damage. However, there may be a benefit to intervening before the development of complications. We sought to characterize institutional trends in the biochemical
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Heart Transplantation for Adults With Congenital Heart Disease Can Be Performed at Adult or Pediatric Hospitals With Comparable Outcomes J. Surg. Res. (IF 2.2) Pub Date : 2024-02-05 Krishna Bhandari, Khaled Shorbaji, Curry Sherard, Sarah Chen, Brett Welch, Arman Kilic
The goal of this study was to evaluate the relationship between hospital-related factors and hospital type on outcomes of heart transplantation for patients with adult congenital heart disease (ACHD). Patients with ACHD who underwent heart transplant between 2010 and 2021 were identified using the United Network for Organ Sharing data registry. The primary outcome was post-transplant mortality. Kaplan–Meier
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Understanding Treatment Decision-Making in Older Women With Breast Cancer: A Survey-Based Study J. Surg. Res. (IF 2.2) Pub Date : 2024-02-05 Ruby J. Kazemi, Callie VanWinkle, Cecilia M. Pesavento, Ton Wang, Lesly A. Dossett
For women ≥70 y old with early-stage hormone receptor–positive, human epidermal growth factor receptor 2–negative breast cancer, the national guidelines recommend the omission of sentinel lymph node biopsy (SLNB) and post-lumpectomy radiotherapy. However, national-level data suggest these treatments remain common. We utilized a survey-based approach to explore patient-level factors driving overutilization
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Renal Dysfunction at Discharge and Long-Term Survival in Acute Type A Aortic Dissection J. Surg. Res. (IF 2.2) Pub Date : 2024-02-05 Elizabeth L. Norton, Faraz N. Longi, Xiaoting Wu, Katelyn Monaghan, Karen M. Kim, Shinichi Fukuhara, Himanshu J. Patel, G. Michael Deeb, Bo Yang
We aimed to investigate the association between renal dysfunction at discharge and long-term survival in acute type A aortic dissection (ATAAD) patients following surgery. From 2000 to 2021, 784 patients underwent aortic repair for an ATAAD. Patients were stratified based on creatinine (Cr) level at discharge alive or dead: normal Cr ( = 582) and elevated Cr defined as >1.3 mg/dL for males and >1.0
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Testing for Primary Hyperparathyroidism in 17,491 Patients With Hypercalcemia J. Surg. Res. (IF 2.2) Pub Date : 2024-02-05 Paul M. Bunch, Joseph Rigdon, Leon Lenchik, Matthew A. Gorris, Reese W. Randle
Primary hyperparathyroidism (PHPT) is underdiagnosed and associated with many adverse health effects. Historically, many hypercalcemic patients have not received parathyroid hormone (PTH) testing; however, underlying reasons are uncertain. Our goals are to determine the PTH testing rate among hypercalcemic individuals at a large academic health system and to assess for characteristics associated with