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Optimizing the transfusion strategy in surgical patients in a Lebanese university hospital Perioper. Med. (IF 2.6) Pub Date : 2024-03-15 Stephanie El Hawat, Rita Saliby, Ghassan Sleilaty, Alain El Asmar, Anthony Ghosn
Our aim was to analyze factors that influence transfusion requirements in surgical patients in order to achieve a transfusion-saving strategy. Data was collected from patient’s files at the Notre Dame de Secours-Jbeil University Hospital Center between January 2017 and June 2019. Selection was made for 400 patients who had undergone surgery and required transfusion. The studied variables were age,
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Analysis of inappropriate prophylactic use of proton pump inhibitors during the perioperative period: an observational study Perioper. Med. (IF 2.6) Pub Date : 2024-03-14 Pengpeng Liu, Guangyao Li, Qian Wu, Mei Han, Chao Zhang
The prevalence and characteristics of inappropriate use of proton pump inhibitors (PPIs) to prevent stress-related mucosal disease (SRMD) during the perioperative period and its associated factors are rarely reported. This study aimed to investigate the prevalence and characteristics of inappropriate prophylactic use of proton pump inhibitors (PPIs) during the perioperative period and identify its
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Acute Pain Services and pain-related patient-reported outcomes in Hungarian hospitals Perioper. Med. (IF 2.6) Pub Date : 2024-03-12 Orsolya Lovasi, Péter Gaál, Krisztián Frank, Judit Lám
Postoperative pain management is an important part of surgical care, where Acute Pain Service offers added value in terms of patient outcomes and costs. The technology, however, has hardly been adopted in Hungary, with only two hospitals operating Acute Pain Service and whose performance has not been evaluated yet. This research compared pain management outcomes of surgical, orthopedic, and traumatology
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Effects of short-term preoperative intranasal dexmedetomidine plus conventional treatment on delirium following cardiac surgery in patients with sleep disorders Perioper. Med. (IF 2.6) Pub Date : 2024-03-09 Jun Fang, Jia Yang, Mingyu Zhai, Qiong Zhang, Min Zhang, Yanhu Xie
To assess whether preoperative dexmedetomidine (DEX) nasal drips combined with conventional treatment could mitigate the occurrence of postoperative delirium (POD). A prospective randomised controlled study. The cardiac surgery intensive care unit (CSICU) and patient hospitalisation ward at a university hospital. A total of 100 patients (aged ≥60 years) undergoing cardiac surgery at a university hospital
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Comparison of metabolic rates of ropivacaine in cerebrospinal fluid as inferred from plasma concentrations between elderly patients and young patients Perioper. Med. (IF 2.6) Pub Date : 2024-03-06 Dongshi Lu, Fei Cai, Yu Ming, Danqing Zhang, Demu Ba, Zhouyang Wu, Zhao Zhang
With the aging of human society, more and more elderly patients have to undergo surgery and anesthesia. Clinical observations have indicated from time to time that spinal anesthesia in the elderly appears to last longer than in young people, although there is limited research in this area and the mechanism is unclear at present time. This research work is expected to help understand the decline of
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Effect of intravenous lidocaine on the ED50 of propofol induction dose in elderly patients undergoing painless gastroscopy: a prospective, randomized, double-blinded, controlled study Perioper. Med. (IF 2.6) Pub Date : 2024-03-05 Lili Tang, Wenhui Lv, Jingjing Sun, Lijian Chen
Intravenous lidocaine could be a potential alternative adjuvant to propofol-based sedation for gastroscopy in elderly patients. This study aimed to evaluate the effect of intravenous lidocaine on the median effective dose (ED50) of propofol induction dose in elderly patients undergoing painless gastroscopy. The study included 70 patients aged ≥ 60 years undergoing painless gastroscopy with 64 randomly
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Pulmonary function testing in preoperative high-risk patients Perioper. Med. (IF 2.6) Pub Date : 2024-03-05 Christine Eimer, Natalia Urbaniak, Astrid Dempfle, Tobias Becher, Dirk Schädler, Norbert Weiler, Inéz Frerichs
Postoperative respiratory failure is the most frequent complication in postsurgical patients. The purpose of this study is to assess whether pulmonary function testing in high-risk patients during preoperative assessment detects previously unknown respiratory impairments which may influence patient outcomes. A targeted patient screening by spirometry and the measurement of the diffusing capacity of
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AcumenTM hypotension prediction index guidance for prevention and treatment of hypotension in noncardiac surgery: a prospective, single-arm, multicenter trial Perioper. Med. (IF 2.6) Pub Date : 2024-03-04 Xiaodong Bao, Sathish S. Kumar, Nirav J. Shah, Donald Penning, Mitchell Weinstein, Gaurav Malhotra, Sydney Rose, David Drover, Matthew W. Pennington, Karen Domino, Lingzhong Meng, Mariam Treggiari, Claudia Clavijo, Gebhard Wagener, Hovig Chitilian, Kamal Maheshwari
Intraoperative hypotension is common during noncardiac surgery and is associated with postoperative myocardial infarction, acute kidney injury, stroke, and severe infection. The Hypotension Prediction Index software is an algorithm based on arterial waveform analysis that alerts clinicians of the patient’s likelihood of experiencing a future hypotensive event, defined as mean arterial pressure < 65
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Preoperative endothelial dysfunction for the prediction of acute kidney injury after cardiac surgery using cardiopulmonary bypass: a pilot study based on a second analysis of the MONS study Perioper. Med. (IF 2.6) Pub Date : 2024-02-29 Stanislas Abrard, Antoine Streichenberger, Jérémie Riou, Jeanne Hersant, Emmanuel Rineau, Matthias Jacquet-Lagrèze, Olivier Fouquet, Samir Henni, Thomas Rimmelé
Up to 42% of patients develop acute kidney injury (AKI) after cardiac surgery. The aim of this study was to describe the relationship between preoperative microcirculatory function and postoperative AKI after cardiac surgery using cardiopulmonary bypass (CPB). The prospective observational cohort MONS enrolled 60 patients scheduled for valvular (n = 30, 50%) or coronary (n = 30, 50%) surgery using
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Sevoflurane preconditioning in living liver donation is associated with better initial graft function after pediatric transplantation: a retrospective study Perioper. Med. (IF 2.6) Pub Date : 2024-02-28 Audrey Dieu, Loïc Benoit, Candice Dupont, Catherine de Magnée, Raymond Reding, Thierry Pirotte, Arnaud Steyaert
Initial allograft function determines the patient’s immediate prognosis in pediatric liver transplantation. Ischemia-reperfusion injuries play a role in initial poor graft function (IPGF). In animal studies, preconditioning with inhaled anesthetic agents has demonstrated a protective effect on the liver. In humans, the few available studies are conflicting. This study assesses the association between
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A new risk calculation model for complications of hepatectomy in adults over 75 Perioper. Med. (IF 2.6) Pub Date : 2024-02-26 Lining Xu, Weiyu Wang, Yingying Xu
Owing to poor organ function reserve, older adults have a high risk of postoperative complications. However, there is no well-established system for assessing the risk of complications after hepatectomy in older adults. This study aimed to design a risk assessment tool to predict the risk of complications after hepatectomy in adults older than 75 years. A total of 326 patients were identified. A logistic
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Comparison of two 3D scanning software to identify facial features: a prospective instrument to predict difficult airway Perioper. Med. (IF 2.6) Pub Date : 2024-02-22 Alexander Rocuts, Bibiana Avella-Molano, Amanda Behr, Farhan Lakhani, Bryant Bolds, Matias Riveros-Amado, Efrain Riveros-Perez
Clinical airway assessment has limited predictive ability to anticipate difficult airway. Three-dimensional (3D) technologies have emerged in medicine as valuable tools in different settings including innovation and surgical planning. Three-dimensional facial scanning could add value to clinical measurements and two-dimensional models to assess the airway. However, commonly used high-fidelity scans
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Impact of preoperative factors and waiting time on post-appendectomy complications: a retrospective study Perioper. Med. (IF 2.6) Pub Date : 2024-02-21 Shuo-Lun Lai, Chin-Hao Chang, Po-Chu Lee, Cheng-Maw Ho, Jin-Ming Wu, Hong-Shiee Lai, Been-Ren Lin
Several factors are associated with increased postoperative complications after appendectomies. However, few studies combined these potential factors for comprehensive prediction of surgical outcomes. Whether high-risk patients benefit from a shorter waiting time for surgery remains unclear. This study aimed to explore the impact of surgical waiting time and potential risk factors on postoperative
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Clinical effect of different concentrations of ropivacaine in the labor analgesia of dural puncture epidural technique for obese puerperae Perioper. Med. (IF 2.6) Pub Date : 2024-02-15 Liping Shi, Difei Zhang, Pengfei Ye, Weihua Peng, Yan Yin, Ye Zhang
This study was performed to analyze the clinical effect of different concentrations of ropivacaine in the labor analgesia of the dural puncture epidural (DPE) technique for obese puerperae. One hundred and fifty first-term obese women who received vaginal delivery and required labor analgesia in our hospital were selected prospectively for this study, and divided into groups A, B, and C. The three
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Multidisciplinary prehabilitation to improve frailty and functional capacity in high-risk elective surgical patients: a retrospective pilot study Perioper. Med. (IF 2.6) Pub Date : 2024-01-23 Henry Man Kin Wong, Ding Qi, Bosco Hon Ming Ma, Pik Yi Hou, Calvin Ka Woon Kwong, Anna Lee
Frailty is associated with worse outcomes and higher healthcare costs. The long waiting time for surgery is a potential ‘teachable’ moment. We examined the feasibility and safety of a pilot prehabilitation programme on high-risk frail patients undergoing major elective surgery. A single-centre, retrospective pilot study (Dec 2020–Nov 2021) on a one-stop prehabilitation programme (structured exercise
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Desmopressin to reduce periprocedural bleeding and transfusion: a systematic review and meta-analysis Perioper. Med. (IF 2.6) Pub Date : 2024-01-23 Carol Wang, Victoria Lebedeva, Jeffy Yang, Joshua Anih, Lily J. Park, Freeman Paczkowski, Pavel S. Roshanov
We systematically reviewed the literature to investigate the effects of peri-procedural desmopressin in patients without known inherited bleeding disorders undergoing surgery or other invasive procedures. We included 63 randomized trials (4163 participants) published up to February 1, 2023. Seven trials were published after a 2017 Cochrane systematic review on this topic. There were 38 trials in cardiac
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Days at home alive after major surgery in patients with and without diabetes: an observational cohort study Perioper. Med. (IF 2.6) Pub Date : 2024-01-22 Amanda Habermann, Matilda Widaeus, Navid Soltani, Paul S. Myles, Linn Hallqvist, Max Bell
We hypothesized that days at home alive up to 30 days after surgery (DAH30), a novel patient-centered outcome metric, as well as long-term mortality, would be impaired in patients with type 1 or 2 diabetes mellitus (DM) undergoing major surgery. This cohort study investigated patients > 18 years with and without DM presenting for major non-cardiovascular, non-ambulatory surgical procedures at 23 hospitals
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Postoperative and postdischarge nausea and vomiting following ambulatory eye, head, and neck surgeries: a retrospective cohort study comparing incidence and associated factors Perioper. Med. (IF 2.6) Pub Date : 2024-01-20 Mark Xiao, Dongdong Yao, Kara G. Fields, Pankaj Sarin, Alvaro Andres Macias, Sunil Eappen, Jeremy Juang
Ambulatory surgery is often followed by the development of nausea and/or vomiting (N/V). Although risk factors for postoperative nausea and vomiting (PONV) are frequently discussed, the distinction between PONV and postdischarge nausea and vomiting (PDNV) is unclear. This is especially troublesome given the potential consequences of postdischarge nausea and vomiting (PDNV), which include major discomfort
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Correction: A comparative study on the effect of dopamine vs phenylephrine in improving the cutaneous analgesic effect of mexiletine in rats Perioper. Med. (IF 2.6) Pub Date : 2024-01-11 Kesong Zheng, Mingming Han, Fang Kang, Chengwei Yang, Juan Li
Correction: Perioperative Medicine 12, 26 (2023) https://doi.org/10.1186/s13741-023-00314-2 Following publication of the original article (Zheng et al. 2023), the author would like to reorder details in affiliation 1. The correction details for the affiliation 1 are: Department of Anesthesiology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and
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Examining workload variations among different surgical team roles, specialties, and techniques: a multicenter cross-sectional descriptive study Perioper. Med. (IF 2.6) Pub Date : 2024-01-02 Sepideh Totonchilar, Akram Aarabi, Naeimeh Eftekhari, Masoumeh Mohammadi
A high workload may negatively impact the surgical team's performance and jeopardize patient safety. The aim of this study was to measure the workload of the surgical team across different surgical roles, specialties, and techniques in several hospitals. This cross-sectional multicenter study was performed in the operating rooms of eight teaching hospitals affiliated with Isfahan University of Medical
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Perioperative Quality Initiative (POQI) consensus statement on perioperative assessment of right ventricular function Perioper. Med. (IF 2.6) Pub Date : 2023-12-08 Stephanie O. Ibekwe, Jean Deschamps, Michael P W Grocott, Yafen Liang, Andrew Shaw, Tjorvi E. Perry
The right ventricle (RV) plays a central role in the maintenance of effective cardiac pump function. Despite overwhelming evidence that perioperative RV dysfunction (RVD) and failure (RVF) are associated with poor clinical outcomes, there are very few published recommendations or guidelines for comprehensive, evidence-based RV assessment on the risk of developing either during the perioperative period
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Prediction of mortality in secondary peritonitis: a prospective study comparing p-POSSUM, Mannheim Peritonitis Index, and Jabalpur Peritonitis Index Perioper. Med. (IF 2.6) Pub Date : 2023-12-08 Akshant Anil Pathak, Vivek Agrawal, Naveen Sharma, Karan Kumar, Chinmay Bagla, Aakash Fouzdar
Risk scoring systems are required to allow accurate prognostication, compare outcomes of surgery, and allow patients to make informed decisions about their health. This prospective study compares the p-POSSUM (Portsmouth Modification to Physiological and Operative Severity Score for Enumeration of Mortality), Mannheim Peritonitis Index, and Jabalpur Peritonitis Index for their utility in predicting
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Anesthetic management of a huge retroperitoneal leiomyoma: a case report Perioper. Med. (IF 2.6) Pub Date : 2023-11-28 Yue Shi, Bo Zhu, Yu Zhang, Yuguang Huang
Retroperitoneal leiomyomas are rare, with just over 100 cases reported in the literature. Perioperative management of retroperitoneal leiomyomas can be challenging due to the large tumor size and the risk of hemorrhage. We report a case of a 40-year-old Han woman with a 40-cm retroperitoneal leiomyoma. General anesthesia was performed for the surgical resection. Key flow parameters like cardiac output
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Fear of anesthesia for cesarean section among pregnant women: a multicenter cross-sectional study Perioper. Med. (IF 2.6) Pub Date : 2023-11-24 Ramzi Shawahna, Mohammad Jaber, Iyad Maqboul, Hatim Hijaz, Eman Arjan, Maisa Karaki, Keen Nasser
Fear of anesthesia for cesarean section delivery is an important health issue that should be addressed by anesthesiologists, obstetricians, and other providers of antenatal and perioperative healthcare. This multicenter study was conducted to assess the fear of anesthesia for cesarean section among Palestinian pregnant women and to identify the predictors of high fear. The study was conducted in a
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The effect of using virtual reality technology on anxiety and vital signs before surgery in patients undergoing open heart surgery Perioper. Med. (IF 2.6) Pub Date : 2023-11-24 Ameneh Amiri, Rostam Jalali, Nader Salari
Preoperative anxiety is one of the most common psychological problems in open-heart surgery patients. Not controlling this problem can negatively the operation outcome and the patient’s physical condition. Among various training methods and tools introduced to deal with this issue, the ideal method still remains unknown. Therefore, the present study was to determine the effect of using virtual reality
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Efficacy and safety of perioperative use of non-steroidal anti-inflammatory drugs for preemptive analgesia in lumbar spine surgery: a systematic review and meta-analysis Perioper. Med. (IF 2.6) Pub Date : 2023-11-23 Nanshan Ma, Ping Yi, Zhencheng Xiong, Haoning Ma, Mingsheng Tan, Xiangsheng Tang
Lumbar spine disorders have become an increasingly common health problem in recent years. Modern clinical studies have shown that perioperative analgesia at certain doses can reduce postoperative pain by inhibiting the process of peripheral sensitization and central sensitization, which is also known as “preemptive analgesia,” Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of drugs that
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Mismatch of populations between randomised controlled trials of perioperative interventions in major abdominal surgery and current clinical practice Perioper. Med. (IF 2.6) Pub Date : 2023-11-16 Elliott Ridgeon, Rory Shadwell, Alice Wilkinson, Peter M. Odor
Demographics of patients undergoing major abdominal surgery are changing. External validity of relevant RCTs may be limited by participants not resembling patients encountered in clinical practice. We aimed to characterise differences in age, weight, BMI, and ASA grade between participants in perioperative trials in major abdominal surgery and patients in a reference real-world clinical practice sample
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Periarticular injection, iPACK block, and peripheral nerve block in pain management after total knee arthroplasty: a structured narrative review Perioper. Med. (IF 2.6) Pub Date : 2023-11-15 Małgorzata Domagalska, Katarzyna Wieczorowska-Tobis, Tomasz Reysner, Grzegorz Kowalski
Total knee arthroplasty (TKA) is commonly performed in patients with end-stage osteoarthritis or rheumatoid arthritis of the knee to reduce joint pain, increase mobility, and improve quality of life. However, TKA is associated with moderate to severe postoperative pain, which remains a significant clinical challenge. Surgeon-administered PAI and anesthesiologist-administered iPACK have proven viable
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Perioperative myocardial injury is associated with increased postoperative non-cardiac complications in patients undergoing vascular surgery: a post hoc analysis of a randomised clinical pilot trial Perioper. Med. (IF 2.6) Pub Date : 2023-11-13 A. Valadkhani, A. Gupta, M. Bell
Elevated cardiac biomarkers, such as high-sensitivity cardiac Troponin T and N-terminal pro-B-type natriuretic peptide improve the prediction of major adverse cardiac events. However, very few trials have investigated the association between perioperative cardiac injury and non-cardiac complications. The primary aim of this study was to determine the association between peri-operative myocardial injury
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Protocol: dexmedetomidine on myocardial injury after noncardiac surgery—a multicenter, double-blind, controlled trial Perioper. Med. (IF 2.6) Pub Date : 2023-11-11 Huayue Liu, Juan Zhang, Ke Peng, Xiaowen Meng, Xisheng Shan, Wenwen Huo, Hong Liu, Yishan Lei, Fuhai Ji
Myocardial injury after noncardiac surgery (MINS) is common in elderly patients and considered as an independent predictor of 30-day mortality after noncardiac surgery. Dexmedetomidine possesses cardiac-protective profile. Previous clinical studies have found that perioperative application of dexmedetomidine is associated with decreased 1-year mortality in patients undergoing cardiac surgery. The current
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Preoperative moderate to severe anemia is associated with increased postoperative major adverse cardiac and cerebral events and pulmonary complications: a propensity score-matched analysis in hip fracture surgery patients over 80 years old Perioper. Med. (IF 2.6) Pub Date : 2023-11-10 Li Min, Yang Linyi, Li Chen, Shen Jiang, Chen Chen
Anemia is a common health problem in the elderly. Preoperative anemia is a risk factor for postoperative outcomes in the elderly for hip fracture. The objective of the study was to explore the relationship between preoperative moderate to severe anemia and postoperative morbidity and mortality in hip fracture patients over 80 years old. We performed a retrospective cohort study exploring preoperative
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The impact of preoperative malnutrition on postoperative delirium: a systematic review and meta-analysis Perioper. Med. (IF 2.6) Pub Date : 2023-10-26 Bo Dong, Jing Wang, Pan Li, Jianli Li, Meinv Liu, Huanhuan Zhang
Postoperative delirium (POD) is a common postoperative complication, characterized by disturbance of attention, perception, and consciousness within 1 week after surgery, and linked to cognitive decline, increased mortality, and other serious surgical outcomes. Early identification and treatment of risk factors for POD could reduce the occurrence of delirium and the related poor outcomes. Malnutrition
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Significant perioperative parameters affecting postoperative complications within 30 days following craniotomy for primary malignant brain tumors Perioper. Med. (IF 2.6) Pub Date : 2023-10-23 Yao-Chung Yang, Yao-Shen Chen, Wei-Chuan Liao, Chun-Hao Yin, Yung-Shang Lin, Meng-Wei Chen, Jin-Shuen Chen
The occurrence of postoperative complications within 30 days (PC1M) of a craniotomy for the removal of a primary malignant brain tumor has been associated with a poor prognosis. However, it is still unclear to early predict the occurrence of PC1M. This study aimed to identify the potential perioperative predictors of PC1M from its preoperative, intraoperative, and 24-h postoperative parameters. Patients
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Unplanned admissions after day-case surgery in an Italian third-level pediatric hospital: a retrospective study Perioper. Med. (IF 2.6) Pub Date : 2023-09-26 Alessandro Vittori, Luigi Tritapepe, Fabrizio Chiusolo, Emanuele Rossetti, Marco Cascella, Emiliano Petrucci, Roberto Pedone, Franco Marinangeli, Elisa Francia, Ilaria Mascilini, Giuliano Marchetti, Sergio Giuseppe Picardo
Increasing procedures in day-case surgery can mitigate the costs of health service, without reducing safety and quality standards. The Ospedale Pediatrico Bambino Gesù has adopted an educational program for healthcare personnel and patients’ families to increase the number of day-case surgery procedures performed without reducing the level of safety. The unplanned admission rate after day-case surgery
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Restrictive versus conventional ward fluid therapy in non-cardiac surgery patients and the effect on postoperative complications: a meta-analysis Perioper. Med. (IF 2.6) Pub Date : 2023-09-21 Joachim J. Bosboom, Marije Wijnberge, Bart F. Geerts, Martijn Kerstens, Michael G. Mythen, Alexander P. J. Vlaar, Markus W. Hollmann, Denise P. Veelo
Diligent fluid management is an instrumental part of Enhanced Recovery After Surgery. However, the effect of a ward regimen to limit intravenous fluid administration on outcome remains unclear. We performed a meta-analysis investigating the effect of a restrictive versus a conventional fluid regimen on complications in patients after non-cardiac surgery in the postoperative period on the clinical ward
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Effect of chamomile intake on blood coagulation tests in healthy volunteers: a randomized, placebo-controlled, crossover trial Perioper. Med. (IF 2.6) Pub Date : 2023-09-20 Jonathon A. Schwartz, Jamie L. Romeiser, Reona Kimura, Lisa Senzel, Dennis Galanakis, Darcy Halper, Shayla Mena, Elliott Bennett-Guerrero
Chamomile is consumed worldwide for enjoyment and its potentially desirable properties. Widespread patient resource websites, however, discourage preoperative chamomile intake, lest bleeding could worsen. This precaution, though, stems largely from indirect evidence in one case report. To evaluate if chamomile ingestion impacts coagulation assays via coumarin-like substances, we designed a randomized
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The effect of COVID-19 pandemic on perioperative factors: data from the Swedish Perioperative Register Perioper. Med. (IF 2.6) Pub Date : 2023-09-16 Karuna Dahlberg, Sandra Månsson, Sara Lyckner, Lenita Lindgren, Fredrik Alm
The COVID-19 pandemic has affected healthcare organizations in many areas. The aim of this study was to describe surgical interventions, anesthesia, and postoperative outcomes in adult patients during the first wave and 1 year into the COVID-19 pandemic in Sweden, and to compare these outcomes with outcomes during the same period the year before the pandemic. Data were collected from the Swedish PeriOperative
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Perioperative mortality of emergency and elective surgical patients in a low-income country: a single institution experience Perioper. Med. (IF 2.6) Pub Date : 2023-09-16 Samrawit Degu, Segni Kejela, Henok TekleSelassie Zeleke
The perioperative mortality rate is an indicator of access to safe anesthesia and surgery. Studies showed higher perioperative mortality rates among low- and middle-income countries. But the specific causes and factors contributing to perioperative death have not been adequately studied in the Ethiopian context. This is a retrospective institutional study of the largest academic medical center in Ethiopia
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Reporting quality of randomized controlled trials in prehabilitation: a scoping review Perioper. Med. (IF 2.6) Pub Date : 2023-08-31 Dominique Engel, Giuseppe Dario Testa, Daniel I. McIsaac, Francesco Carli, Daniel Santa Mina, Gabriele Baldini, Celena Scheede-Bergdahl, Stéphanie Chevalier, Linda Edgar, Christian M. Beilstein, Markus Huber, Julio F. Fiore, Chelsia Gillis
Inadequate study reporting precludes interpretation of findings, pooling of results in meta-analyses, and delays knowledge translation. While prehabilitation interventions aim to enhance candidacy for surgery, to our knowledge, a review of the quality of reporting in prehabilitation has yet to be conducted. Our objective was to determine the extent to which randomized controlled trials (RCTs) of prehabilitation
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Prevalence of preoperative anxiety among hospitalized patients in a developing country: a study of associated factors Perioper. Med. (IF 2.6) Pub Date : 2023-08-24 Ramzi Shawahna, Mohammad Jaber, Iyad Maqboul, Hatim Hijaz, Marah Tebi, Nada Al-Sayed Ahmed, Ziyad Shabello
Preoperative anxiety is a health concern among patients scheduled for surgical interventions. Little is known about the prevalence of preoperative anxiety among patients in different healthcare systems of developing countries. This study was conducted to determine the prevalence of preoperative anxiety among patients undergoing surgery in Palestine. Another objective was to identify the factors associated
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Comparison of two handgrip dynamometers in older adults before elective surgery Perioper. Med. (IF 2.6) Pub Date : 2023-08-23 Maricarmen S. Andrade, Macarena P. Honorato, Javiera P. Vargas, María de los Angeles Galvez, Mariana R. Rojas
Handgrip strength is a useful measurement of muscle strength and has been proposed as a single predictor of postoperative outcomes in older adults. The aim of this study was to assess the correlation and concordance of Camry digital hand grip dynamometer (EH101) with gold standard Jamar® hydraulic handgrip dynamometer in older adults previous to elective surgery. A cross-sectional study was conducted
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Outpatient compared to inpatient thyroidectomy on 30-day postoperative outcomes: a national propensity matched analysis Perioper. Med. (IF 2.6) Pub Date : 2023-08-08 Lauren Traill, Mark C. Kendall, Maria Paula Caramez, Patricia Apruzzese, Gildasio De Oliveira
To address the postoperative outcomes between outpatient and inpatient neck surgery involving thyroidectomy procedures. A cohort analysis of surgical patients undergoing primary, elective, total thyroidectomy from multiple United States medical institutions who were registered with the American College of Surgeons National Surgical Quality Improvement Program from 2015 to 2018. The primary outcome
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Randomized controlled trial of liberal vs. standard fasting instructions in percutaneous cardiac procedures Perioper. Med. (IF 2.6) Pub Date : 2023-08-08 Derek J. Atkinson, Jamie L. Romeiser, Ibrahim O. Almasry, Henry J. Tannous, Puja B. Parikh, Elliott Bennett-Guerrero
Pre-procedural fasting to reduce aspiration risk is usual care prior to surgery requiring anesthesia. Prolonged fasting, however, can result in dehydration and may adversely affect patient experience and outcomes. Previous studies suggest that providing a supplemental beverage to patients undergoing cardiac and a variety of other surgical procedures improves patients’ subjective assessment of thirst
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A multidisciplinary opioid-reduction pathway for robotic prostatectomy: outcomes at year one Perioper. Med. (IF 2.6) Pub Date : 2023-08-01 Michael W. Manning, John Whittle, Matthew Fuller, Sara H. Cooper, Erin L. Manning, Joe Chapman, Judd W. Moul, Timothy E. Miller
Opioid use has come under increasing scrutiny, driven in part by the opioid crisis and growing concerns that up to 6% of opioid-naïve patients may become chronic opioid users. This has resulted in a revaluation of perioperative practice. For this reason, we implemented a multidisciplinary pathway to reduce perioperative opioid usage through education and standardization of practice. A single-centre
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Risk factors for postoperative cognitive dysfunction in elderly patients undergoing surgery for oral malignancies Perioper. Med. (IF 2.6) Pub Date : 2023-07-20 Yujia Wu, Cong Yu, Feng Gao
We aimed to analyse postoperative cognitive dysfunction (POCD) incidence and risk factors in elderly adults who underwent surgery for oral malignancies. A total of 112 elderly patients (aged ≥ 55 years) were selected for expanded resection of oral malignancy and cervical lymphatic dissection at our institution from December 2020 to December 2021. Participants were cognitively evaluated using the neuropsychological
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Multimodal prehabilitation in patients with non-small cell lung cancer undergoing anatomical resection: protocol of a non-randomised feasibility study Perioper. Med. (IF 2.6) Pub Date : 2023-07-19 Charlotte Johanna Laura Molenaar, Erik Martin Von Meyenfeldt, Carlijn Tini Ireen de Betue, Rosaline van den Berg, David Wouter Gerard ten Cate, Goof Schep, Magdolen Youssef-El Soud, Eric van Thiel, Nicky Rademakers, Sanne Charlotte Hoornweg, Gerrit Dirk Slooter, Frank van den Broek, Geertruid Marie Heleen Marres
The preoperative period can be used to enhance a patient’s functional capacity with multimodal prehabilitation and consequently improve and fasten postoperative recovery. Especially, non-small cell lung cancer (NSCLC) surgical patients may benefit from this intervention, since the affected and resected organ is an essential part of the cardiorespiratory fitness. Drafting a prehabilitation programme
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Postoperative analgesia for upper gastrointestinal surgery: a retrospective cohort analysis Perioper. Med. (IF 2.6) Pub Date : 2023-07-18 Katrina P. Pirie, Andy Wang, Joanna Yu, Bao Teng, Matthew A. Doane, Paul S. Myles, Bernhard Riedel
Thoracic epidural analgesia is commonly used for upper gastrointestinal surgery. Intrathecal morphine is an appealing opioid-sparing non-epidural analgesic option, especially for laparoscopic gastrointestinal surgery. Following ethics committee approval, we extracted data from the electronic medical records of patients at Royal North Shore Hospital (Sydney, Australia) that had upper gastrointestinal
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Ability of the integrated pulmonary index to predict impending respiratory events in the early postoperative period Perioper. Med. (IF 2.6) Pub Date : 2023-07-17 Stephen Probst, Jamie Romeiser, Tong J. Gan, Darcy Halper, Andrew R. Sisti, Hiroshi Morimatsu, Kentaro Sugimoto, Elliott Bennett-Guerrero
In the early postoperative period, respiratory compromise is a significant problem. Standard-of-care monitoring includes respiratory rate (RR) and pulse oximetry, which are helpful; however, low SpO2 is often a late sign during decompensation. The FDA-approved Capnostream-20p monitor records four variables (SpO2, RR, End-tidal CO2, heart rate), which are combined by fuzzy logic into a single, unit-less
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Effects of opioid-free total intravenous anesthesia on postoperative nausea and vomiting after treatments of lower extremity wounds: protocol for a randomized double-blind crossover trial Perioper. Med. (IF 2.6) Pub Date : 2023-07-14 Ya-juan Zhu, Dan Wang, Yu-qin Long, Long Qian, Hong Liu, Fu-hai Ji, Ke Peng
Postoperative nausea and vomiting (PONV) are common after general anesthesia and surgery. This study aims to compare the effects of total intravenous opioid-free anesthesia (OFA) with conventional opioid-based anesthesia (OBA) on PONV in patients following treatments for wounds of lower extremities. This randomized, double-blind, crossover trial will include a total of 72 adult patients scheduled for
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“A breach in the protocol for no good reason”: a surgical antimicrobial prophylaxis experience in an Ethiopian academic medical center Perioper. Med. (IF 2.6) Pub Date : 2023-07-13 Veronica Afework, Segni Kejela, Nebyou Seyoum Abebe
An appropriately administered surgical antimicrobial prophylaxis decreases the rate of surgical site infections. Although evidence-based clinical practice guidelines have been published on surgical antimicrobial prophylaxis, the rate of adherence to the protocol and the impact of extending antimicrobial prophylaxis postoperatively is yet to be well elucidated. A total of general surgery and vascular
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Treatment of iron deficiency in patients scheduled for pancreatic surgery: implications for daily prehabilitation practice in pancreatic surgery Perioper. Med. (IF 2.6) Pub Date : 2023-07-11 Allard G. Wijma, Michele F. Eisenga, Maarten W. Nijkamp, Frederik J. H. Hoogwater, Joost M. Klaase
Preoperative anemia is a frequent complication in pancreatic surgical patients, and it adversely affects morbidity, mortality, and postoperative red blood cell (RBC) transfusion rates. Iron deficiency (ID) is often the underlying cause of anemia and constitutes a modifiable risk factor. Single-center, longitudinal prospective cohort study conducted between May 2019 and August 2022 at the University
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Perioperative redox changes in patients undergoing hepato-pancreatico-biliary cancer surgery Perioper. Med. (IF 2.6) Pub Date : 2023-07-10 Jia L. Stevens, Helen T. McKenna, Helder Filipe, Laurie Lau, Bernadette O. Fernandez, Andrew J. Murray, Martin Feelisch, Daniel S. Martin
Tissue injury induces inflammation and the surgical stress response, which are thought to be central to the orchestration of recovery or deterioration after surgery. Enhanced formation of reactive oxygen and nitrogen species accompanies the inflammatory response and triggers separate but integrated reduction/oxidation (redox) pathways that lead to oxidative and/or nitrosative stress (ONS). Quantitative
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Process, structural, and outcome quality indicators to support perioperative opioid stewardship: a rapid review Perioper. Med. (IF 2.6) Pub Date : 2023-07-10 C. Thomas, M. Ayres, K. Pye, D. Yassin, S. J. Howell, S. Alderson
Opioids are effective analgesics but can cause harm. Opioid stewardship is key to ensuring that opioids are used effectively and safely. There is no agreed set of quality indicators relating to the use of opioids perioperatively. This work is part of the Yorkshire Cancer Research Bowel Cancer Quality Improvement programme and aims to develop useful quality indicators for the improvement of care and
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The effect of intraoperative goal-directed fluid therapy combined with enhanced recovery after surgery program on postoperative complications in elderly patients undergoing thoracoscopic pulmonary resection: a prospective randomized controlled study Perioper. Med. (IF 2.6) Pub Date : 2023-07-10 Hongmei Ma, Xin Li, Zhe Wang, Qiao Qiao, Yanfeng Gao, Hui Yuan, Bin Guan, Zheng Guan
To investigate the effect of intraoperative goal-directed fluid therapy (GDFT) combined with enhanced recovery after surgery (ERAS) program on postoperative complications in elderly patients undergoing thoracoscopic pulmonary resection. Patients, more than 60 years old, undergoing thoracoscopic pulmonary resection for non-small cell lung cancer were randomly divided into GDFT group and restrictive
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Effects of goal-directed fluid management guided by a non-invasive device on the incidence of postoperative complications in neurosurgery: a pilot and feasibility randomized controlled trial Perioper. Med. (IF 2.6) Pub Date : 2023-07-05 Ondrej Hrdy, Milos Duba, Andrea Dolezelova, Ivana Roskova, Martin Hlavaty, Rudolf Traj, Vit Bönisch, Martin Smrcka, Roman Gal
The positive effects of goal-directed hemodynamic therapy (GDHT) on patient-orientated outcomes have been demonstrated in various clinical scenarios; however, the effects of fluid management in neurosurgery remain unclear. Therefore, this study was aimed at assessing the safety and feasibility of GDHT using non-invasive hemodynamic monitoring in elective neurosurgery. The incidence of postoperative
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Cardiopulmonary exercise testing before and after intravenous iron in preoperative patients: a prospective clinical study Perioper. Med. (IF 2.6) Pub Date : 2023-07-03 James O. M. Plumb, James M. Otto, Shriya B. Kumar, Sitara Bali, Mai Wakatsuki, Walter F. J. Schmidt, Hugh E. Montgomery, Michael P. W. Grocott, Denny Z. Levett
Anemia is associated with impaired physical performance and adverse perioperative outcomes. Iron-deficiency anemia is increasingly treated with intravenous iron before elective surgery. We explored the relationship between exercise capacity, anemia, and total hemoglobin mass (tHb-mass) and the response to intravenous iron in anemic patients prior to surgery. A prospective clinical study was undertaken
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A preoperative ultrasound-based protocol for optimisation of fluid therapy to prevent early intraoperative hypotension: a randomised controlled study Perioper. Med. (IF 2.6) Pub Date : 2023-06-27 Marcell Szabó, András Péter Pleck, Sándor Árpád Soós, Bánk Keczer, Balázs Varga, János Széll
Intraoperative hypotension is a risk factor for postoperative complications. Preoperative dehydration is a major contributor, although it is difficult to estimate its severity. Point-of-care ultrasound offers several potential methods, including measurements of the inferior vena cava. The addition of lung ultrasound may offer a safety limit. We aimed to evaluate whether the implication of an ultrasound-based
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Incidence of intraoperative hypotension during non-cardiac surgery in community anesthesia practice: a retrospective observational analysis Perioper. Med. (IF 2.6) Pub Date : 2023-06-24 Wael Saasouh, Anna L. Christensen, Fei Xing, Desirée Chappell, Josh Lumbley, Brian Woods, Monty Mythen, Richard P. Dutton
Intraoperative hypotension (IOH) is well-described in the academic setting but not in community practice. IOH is associated with risk of postoperative morbidity and mortality. This is the first report of IOH in the community setting using the IOH measure definition from the Centers for Medicare and Medicaid Services Merit-based Incentive Payment System program. Objectives: To describe the incidence
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Postoperative rehospitalization in older surgical patients: an age-stratified analysis Perioper. Med. (IF 2.6) Pub Date : 2023-06-21 Caroline Andrew, Christina M. Fleischer, Pablo Martinez Camblor, Vinca Chow, Alexandra Briggs, Stacie Deiner
Older adults comprise 40% of surgical inpatients and are at increased risk of postoperative rehospitalization. A decade ago, 30-day rehospitalizations for Medicare patients were reported as 15%, and more than 70% was attributed to medical causes. In the interim, there have been several large-scale efforts to establish best practice for older patients through surgical quality programs and national initiatives
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Comparison of tramadol and lornoxicam for the prevention of postoperative catheter-related bladder discomfort: a randomized controlled trial Perioper. Med. (IF 2.6) Pub Date : 2023-06-19 Xin Liao, Min Xie, Shuying Li, Xiaolan Yu
Catheter-related bladder discomfort (CRBD is a painful complication of intraoperative urinary catheterization after anaesthesia. We conducted this study to compare the effect of tramadol and lornoxicam for the prevention of postoperative CRBD. One-hundred twenty patients (aged 18–60 years, ASA physical status 1–2, undergoing elective uterine surgery requiring intraoperative urinary catheterization