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A Historic Cohort Analysis of Radiographic and Serologic Findings in Patients With Scleroderma and Interstitial Lung Disease. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-11-20 Nikita Jhawar,Claire Wilson,Zhuo Li,Yaohua Ma,Andy Abril
BACKGROUND/OBJECTIVE Few studies have investigated associations between rheumatologic serology patterns and different interstitial lung disease (ILD) patterns. METHODS We present novel findings of a historic cohort study (n = 454) with data collected from 2011 to 2021 within our hospital system. In this institutional review board-approved study, data regarding rheumatologic serologies and ILD patterns
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Analytic and Clinical Validity of Myositis-Specific Antibodies by Line-Blot Immunoassay Is Essential. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-11-20 Chih-Wei Tseng,Minoru Satoh,Tomoko Hasegawa,Shin Tanaka,Yi-Ming Chen
OBJECTIVES This study assessed the concordance between line blot (LB) and immunoprecipitation (IP) assays for detecting myositis-specific antibodies (MSAs) in idiopathic inflammatory myopathies (IIMs) and their association with IIM subtypes. METHODS One hundred patients with IIM were enrolled, and MSA was detected using LB and IP. The IIM subtypes, including immune-mediated necrotizing myopathy-like
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What Bedside Skills Could the Modern Rheumatologist Possess? Part II. "Certain Technical Procedures". JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-11-20 Robert W Ike,Sara S McCoy,Kenneth C Kalunian
Rheumatologists have never been reluctant to adopt procedures that might enhance their diagnostic or therapeutic powers. Their propensity to penetrate the joints of the patients they were treating set them apart from the general internist. Since the 1980s, when a chance to look inside the joints they were treating attracted a few rheumatologists, other things that could be done at the bedside emerged
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Factors Associated With Mortality in Patients With Immune-Mediated Rheumatic Diseases and COVID-19 From Latin America: Data From Argentina, Mexico, and Brazil. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-11-20 Carolina Ayelen Isnardi,Deshire Alpizar-Rodriguez,Débora Cerqueira Calderaro,Claudia Diniz Lopes Marques,Guillermo Javier Pons-Estel,Ricardo Machado Xavier,Verónica Saurit,Cecilia Nora Pisoni,Yohana Soledad Tissera,Maria Eugenia D'Angelo Exeni,Paula Alba,Dora Pereira,Carla Andrea Gobbi,Maria Julieta Gamba,María Agustina Alfaro,Belén María Virasoro,Iris Jazmín Colunga-Pedraza,Fedra Irazoque-Palazuelos
OBJECTIVE To describe characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in patients with rheumatic immune-mediated inflammatory diseases (IMIDs) from Argentina, Mexico and Brazil, and to assess factors associated with mortality in this population. METHODS Data from 3 national registries, SAR-COVID (Argentina), CMR-COVID (Mexico), and ReumaCoV-Brasil (Brazil)
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Factors Associated With COVID-19 Vaccine Hesitancy in Rheumatology Outpatients in New York City. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-11-10 Medha Barbhaiya,Brandon Schneider,Jonah M Levine,Omar Bruce,Huong Do,Caroline H Siegel,Vivian P Bykerk,Candace H Feldman,Deanna Jannat-Khah,Lisa A Mandl
OBJECTIVE The aim of this study was to measure COVID-19 vaccine hesitancy among rheumatology outpatients from an early COVID-19 "hotspot" during the initial period of vaccine availability. METHODS In March 2021, a Web-based survey was sent to 7505 adults seen at a Rheumatology Division in New York City. We evaluated characteristics associated with 3 categories of COVID-19 vaccination status: declined
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Association Between Herpes Simplex Virus II Infection and Rheumatoid Arthritis in US Adults: A Population-Based Propensity Score-Matching Study. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-11-10 Tieh-Cheng Fu,Jr-Rung Lin,Ching-Mao Chang
BACKGROUND/OBJECTIVE The potential correlation between herpes simplex virus (HSV) and human papillomavirus (HPV) infections and rheumatoid arthritis (RA) has not been definitively established. Further research is needed to determine the relationship between the development of RA and the presence of these viral infections. METHODS A retrospective case-control study was conducted with data from the National
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Sedimentation Sign in Tumoral Calcinosis in Systemic Sclerosis. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-11-08 Ebonii-Mykel Grosvenor,Cindy Flower
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Immunoglobulin A Vasculitis as a Sign of Recurrence of Lingual Cancer. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-10-24 Hirotaka Yamamoto,Yoshinori Taniguchi
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Impact of the COVID-19 Pandemic on the Management of Juvenile Idiopathic Arthritis: Analysis of United States Commercial Insurance Data. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-10-12 Daniel B Horton,Yiling Yang,Amanda Neikirk,Cecilia Huang,Stephen Crystal,Amy Davidow,Kevin Haynes,Tobias Gerhard,Carlos D Rose,Brian L Strom,Lauren Parlett
BACKGROUND/OBJECTIVE Given limited information on health care and treatment utilization for juvenile idiopathic arthritis (JIA) during the pandemic, we studied JIA-related health care and treatment utilization in a commercially insured retrospective US cohort. METHODS We studied rates of outpatient visits, new disease-modifying antirheumatic drug (DMARD) initiations, intra-articular glucocorticoid
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Association of Systemic Lupus Erythematosus Disease Activity With Choroidal Thickness. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-10-12 Iris Lee,Andrea Ramirez Gomez,Alfred H J Kim,Dean W Coble,Brigid Marshall,Aaditya Shah,Seth Eisen,Rajendra S Apte,Tingting Li
OBJECTIVE To determine the association between disease activity and choroidal thickness in patients with systemic lupus erythematosus (SLE). METHODS We conducted a cohort study of 24 SLE patients and 13 healthy controls recruited at Washington University School of Medicine between June 2019 and November 2021. SLE disease activity was assessed using the SLE Disease Activity Index-2000 Responder Index-50
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Burden of Other Musculoskeletal Disorders in Latin America and the Caribbean: Findings of Global Burden of Disease Study 2019. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-10-06 Claudia Mendoza-Pinto,Ivet Etchegaray-Morales,Pamela Munguía-Realpozo,Adriana Rojas-Villarraga,Ángel David Osorio-Peña,Socorro Méndez-Martínez,Mario García-Carrasco
OBJECTIVE To describe the results from the Global Burden Disease (GBD) study 2019 on the burden of other musculoskeletal (MSK) disorders in Latin America and the Caribbean (LAC). METHODS In this cross-sectional study, we analyzed data from all LAC region in the GBD study from 1990 to 2019. Other MSK (other than rheumatoid arthritis, osteoarthritis, gout, low back pain, and neck pain) burden was measured
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Characteristics and Disease Burden of Patients With Eosinophilic Granulomatosis With Polyangiitis Initiating Mepolizumab in the United States. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-10-02 Jared Silver,Arijita Deb,Elizabeth Packnett,Donna McMorrow,Cynthia Morrow,Michael Bogart
BACKGROUND/OBJECTIVE Although the high disease burden associated with eosinophilic granulomatosis with polyangiitis (EGPA) has been established, the disease burden in patients initiating mepolizumab in real-world practice is poorly understood. This study aimed to assess characteristics and burden of real-world patients with EGPA initiating mepolizumab. METHODS This was a database study (GSK study ID:
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Clinical Efficacy of 2-Needle Joint Lavage for Osteoarthritis-Related Knee Pain and Predictors of Response Based on Knee MRI Osteoarthritis Knee Score: A Medical Records Review Study. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-10-02 Shiyao Li,Xiaohan Jiang,Junnan Wang,Yang Chen,Rongchao Shi,Feier Ding,Lingyan Chu,Tao Sun
BACKGROUND Knee osteoarthritis (OA) is notoriously difficult to treat. Pain is the key symptom for patients to seek medical attention. This study aimed to evaluate the therapeutic efficacy of joint lavage (JL) for OA-related knee pain and to explore the knee pathological changes detected by magnetic resonance imaging that may affect the prognosis of patients who received JL. METHODS Eighty-two hospitalized
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Can Whole-Body Magnetic Resonance Imaging Predict Relapse in Juvenile Idiopathic Arthritis? A Longitudinal Pilot Study. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-10-02 Deeksha Bhalla,Narendra Bagri,Manisha Jana,Ashish Datt Upadhyay
OBJECTIVE To determine the utility of whole-body magnetic resonance imaging (WB MRI) to predict relapse in children with juvenile idiopathic arthritis (JIA) in clinical remission. METHODS Consecutive patients with JIA who fulfilled the Wallace criteria for remission were recruited into this longitudinal pilot study and underwent WB MRI. A radiological score was devised, incorporating synovitis, bone
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Clinical Characteristics and Prognostic Value of Ro52/SSA Antibodies in Idiopathic Inflammatory Myopathies. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-10-01 Elizabeth Pepper,Lilian Vilar,Ian M Ward
BACKGROUND/PURPOSE Anti-Ro52 are myositis-associated antibodies found in idiopathic inflammatory myopathies (IIMs). This chart review aims to evaluate the frequency, significance, and associated clinical characteristics of Ro52/SSA positivity in IIM patients. METHODS We performed a chart review of IIM patients diagnosed between January 2006 and December 2020. All patients met either the 1975 Bohan
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HLA Alleles in a Behçet Disease Multiethnic Population With and Without Ophthalmic Manifestations. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-10-01 Francisco Assis de Andrade,Luís Cristóvão Porto,Manuella Lima Gomes Ochtrop,Ana Beatriz Santos Bacchiega,Ricardo de Almeida Neves,Leonardo Morette,Gilson Santos,Alexandre Wagner Silva de Souza,Kimble Matos,Roger Abramino Levy
OBJECTIVE The aim of this study was to analyze HLA alleles in patients with Behçet disease (BD) and their correlation with ophthalmic manifestations (OMs) in a multiethnic Brazilian population. METHODS This case-control study compared 72 BD patients with or without OM who underwent a thorough ophthalmologic evaluation, including best-corrected visual acuity, bino-ophthalmoscopy, and HLA analysis, with
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Unintentional Monotherapy in Rheumatoid Arthritis Patients Receiving Tofacitinib and Drug Survival Rate of Tofacitinib. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-09-19 Nevsun Inanc,Kerem Y Abacar,Mehmet A Ozturk,Abdurrahman Tufan,Hazan Karadeniz,Ismail Sari,Gercek Can,Yesim Erez,Yavuz Pehlivan,Huseyin E Dalkilic,Tugba Ocak,Ayse Cefle,Ayten Yazici,Abdurrahman S Senel,Servet Akar,Elif Durak-Ediboğlu,Suleyman S Koca,Rabia Piskin-Sagir,Sema Yilmaz,Semral Gulcemal,Ozgul Soysal-Gunduz,Canberk S Basibuyuk,Serdar Alkan,Teoman Y Cesur,Fatos Onen
OBJECTIVE To determine the rate of unintentional monotherapy (UM; switching to monotherapy from combination therapy of patients' own volition) in rheumatoid arthritis patients receiving tofacitinib and to evaluate tofacitinib survival rate. METHODS This national, multicenter study included patients' data from the TURKBIO Registry. Demographics, clinical characteristics, disease duration and activity
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Clinical Features and Imaging Characteristics of Intracranial Vascular Involvement in Takayasu Arteritis: An Analysis of 9 Cases. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-09-19 Sandeep Yadav,Rohini Samant,Aditi Patankar,Charulata Sankhla
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HIV-Associated Rheumatic Diseases: A Narrative Review. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-09-19 Bushra Akram,Meeshal Khan,Mary Beth Humphrey
Human immunodeficiency virus (HIV) is widely prevalent among the world population. Although, historically, it has been linked to opportunistic infections in keeping with immunodeficiency and immune dysregulation, it has also been associated with a wide variety of autoimmune manifestations. With the introduction of highly active antiretroviral therapy and subsequent restoration of immunity, there have
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Evaluation of Gastrointestinal System Complaints and Comorbidities in Pediatric Familial Mediterranean Fever Patients. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-09-19 Hatice Dilara Karakas,Zarife Kuloglu,Fatma Aydin,Serpil Ozdemir,Pinar Ozge Avar-Aydin,Ceyda Tuna Kirsaclioglu,Nilgun Cakar,Zeynep Birsin Ozcakar
OBJECTIVE Familial Mediterranean fever (FMF) is the most prevalent hereditary autoinflammatory disease among children. Abdominal pain and various gastrointestinal system (GIS) manifestations may arise directly from FMF or concomitantly with FMF. This study aimed to evaluate GIS complaints and findings other than classic peritonitis attacks in patients with FMF and to interpret concomitant GIS and hepatic
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Response to: "Interleukin-23 Blockade Is Not Effective in Axial Spondyloarthritis". JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-09-07 Eric Peters,Richard C Chou,Stephen J Rozzo,Siu-Long Yao,Ferran José García Fructuoso
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Interleukin-23 Blockade Is Not Effective in Axial Spondyloarthritis. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-09-07 Daniel Wendling
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Multiple Myeloma-Associated Leukocytoclastic Vasculitis Mimicking Autoimmune Vasculitis. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-08-30 Kenji Ishiguro,Shunta Kaneko
A 52-year-old man was admitted because of complaints of swelling and skin rashes on the extremities, fever, and arthralgia. Physical examination revealed bilateral ankle and wrist joint tenderness and livedo racemosa and purpura on the lower extremities (Figure, A). Cutaneous lesion biopsy showed leukocytoclastic vasculitis (Figure, B). Laboratory testing revealed a hemoglobin level of 5.6 g/dL, mildly
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Barriers and Solutions for Pediatric Rheumatology Referrals in a Rural Area: Physician Survey Results From Montana State. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-08-30 Julie A Campbell,Lauren Wilson,Susan Shenoi
BACKGROUND Currently, there are 9 states across the United States that do not have a pediatric rheumatologist, including the state of Montana. Patients in these states are often cared for by outreach clinics staffed by pediatric rheumatology (PR) providers from other states or looked after by in-state adult rheumatologists or in-state primary care providers. METHODS Using a web-based survey, we determined
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Clinical Use of Belimumab for Systemic Lupus Erythematosus in the Setting of Advanced Chronic Kidney Disease and End-Stage Kidney Disease on Dialysis: A Case Series. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-08-25 Matthew S Snyder,Angel Chen,Richard Furie,Sonali Narain,Galina S Marder
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Does the Type of Failure and the Choice of the Second Biologic Influence Response and Persistence on Medication in Rheumatoid Arthritis? JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-08-24 Louis Bessette,Mohammad Movahedi,George Reed,Joel M Kremer,Kevin Kane,Edward Keystone
BACKGROUND The type of failure may predict response to a second biologic. We evaluated the response to a second tumor necrosis factor inhibitor (TNFi) or non-TNFi in patients failing their initial TNFi, either primarily or secondarily. METHODS Patients with rheumatoid arthritis who were biologic-naive and had a Clinical Disease Activity Index (CDAI) >10, who started their first TNFi for ≥3 months and
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What Bedside Skills Could the Modern Rheumatologist Possess? Part I. The Basics. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-08-09 Robert W Ike,Sara S McCoy,Kenneth C Kalunian
The hands-on aspect of rheumatologic practice serves to balance its more cerebral features with the everyday necessity to touch patients to assess their condition, obtain samples for diagnosis, and deliver therapy, all cementing the important bond between patient and physician. Factors over recent years, ranging from the intercession of the electronic medical record to COVID, have weakened this bond
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Aortitis in Eosinophilic Granulomatosis With Polyangiitis. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-08-08 Hirotaka Yamamamoto,Yoshinori Taniguchi
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Letter to the Editor: Argentine Guidelines for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis in Postmenopausal Women and Men Aged 50 Years and Older. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-08-08 Jorge Luis Alberto Morales Torres,Luis Fernando Vidal Neira,Osvaldo Daniel Messina,Willem Lems,Cristiano Zerbini
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Ulcerative Gottron Papules in Association With Transcriptional Intermediary Factor 1-γ Antibody. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-07-27 Eaman Alhassan
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Relapsing-Remitting Form of Arthropathy Occurs in Patients With Mast Cell Activation Syndrome. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-07-27 Carlos A Cañas,Gabriel J Tobón,Fabio Bonilla-Abadía,Iván Posso-Osorio
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Cervical Spine Erosions Mimicking Vertebral Fractures. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-07-27 Sandy Lee
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The Juvenile Spondyloarthritis Disease Activity Index Is a Useful Tool in Enthesitis-Related Arthritis: Real-Life Data. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-07-26 Merve Cansu Polat,Zahide Ekici Tekin,Elif Çelikel,Vildan Güngörer,Tuba Kurt,Melike Mehveş Kaplan,Nilüfer Tekgöz,Müge Sezer,Cüneyt Karagöl,Serkan Coşkun,Nimet Öner,Serdar Sezer,Banu Çelikel Acar
OBJECTIVE To compare enthesitis-related arthritis (ERA) patients with active and inactive disease at 6 months and define baseline predictors for disease inactivity. In addition, to evaluate the demographic, clinical, and laboratory characteristics of ERA patients and to identify the real-life impact of the Juvenile Spondyloarthritis Disease Activity Index (JSpADA) in predicting active disease in ERA
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Efficacy and Safety of Tofacitinib in Anti-Melanoma Differentiation-Associated 5 Gene Antibody-Positive Dermatomyositis. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-07-26 Shanshan Li,Sizhao Li,Jinping Wang,Ling Zhang,Jianghui Duan,Xin Lu,Lu Zhang,Guochun Wang
OBJECTIVES This study aimed to evaluate the efficacy and safety of tofacitinib for the treatment of anti-melanoma differentiation-associated 5 gene (anti-MDA5) antibody-positive dermatomyositis (DM). METHODS This study included 52 patients with anti-MDA5 antibody-positive DM (MDA5 + DM) who were treated with tofacitinib and followed up. Clinical and laboratory data of these patients were recorded between
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The Effect of Clinical and Genetic Variables of Familial Mediterranean Fever Patients: Real Life Data. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-07-26 Nimet Öner,Elif Çelikel,Vildan Güngörer,Zahide Ekici Tekin,Serkan Coşkun,Cüneyt Karagöl,Müge Sezer,Nilüfer Tekgöz,Melike Mehveş Kaplan,Merve Cansu Polat,Banu Çelikel Acar
BACKGROUND The Eurofever/the Pediatric Rheumatology International Trials Organization (PRINTO) classification criteria for familial Mediterranean fever (FMF) include a combination of clinical symptoms and genotype. The pathogenicity of gene variants associated with FMF is categorized by the International Study Group for Systemic Autoinflammatory Diseases (INSAID) classification criteria. OBJECTIVE
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Bilateral Achilles Tendinopathy and Rupture With Fluoroquinolone Use. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-07-11 Joanne S Cunha,Anthony M Reginato
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Characteristics of Patients With Behçet Disease From the Van Province, Eastern Turkey: Definition of Disease Clusters in a Tertiary Referral Center. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-06-28 Emin Oguz,Murat Bektaş
BACKGROUND Behçet disease (BD) is a chronic inflammatory systemic disease that affects skin mucosa, joints, eyes, and blood vessels. Behçet disease shows some clinical differences in terms of disease manifestations and prognosis among the Silk Road countries, as well as various ethnicities even in the same country. In this study, we aimed to evaluate the clinical features and disease course of BD using
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Hypertrophic Osteoarthropathy Associated With Pancoast Tumor: Do Not Miss Secondary Hypertrophic Osteoarthropathy! JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-06-28 Hirotaka Yamamoto,Yoshinori Taniguchi
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Palliative Care Utilization for Hospitalized Patients With Inclusion Body Myositis: A Nationwide Study. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-06-28 Kamini Kuchinad,Mahrukh Nadeem,Ambereen Kurwa Mehta,David Shih Wu,Ché Matthew Harris,Jemima Albayda
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Eosinophilic Fasciitis: A Rare Mimicker of Systemic Sclerosis. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-06-21 Seth J VanDerVeer,Kyle D Maier
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Polyarteritis Nodosa: Gangrene in a Rheumatoid Arthritis Patient. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-06-20 Yuki Koshida,Takashi Yamane
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Localized Scleroderma in an African American. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-06-20 Seth J VanDerVeer,Kyle D Maier
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The Retroperitoneal Space: A Forgotten Place of Serious Disease. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-05-31 Ricardo Craveiro Costa,Rita Marchante Pita,João Nascimento,Carmen do Carmo,Paula Estanqueiro,Manuel Salgado
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The Association of Grit With Burnout Components (Professional Efficacy, Exhaustion, and Cynicism) Among Academic Rheumatologists: The TRUMP 2 -SLE Study. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-05-25 Yoshia Miyawaki,Ken-Ei Sada,Kenta Shidahara,Shoichi Nawachi,Yosuke Asano,Yu Katayama,Keigo Hayashi,Eri Katsuyama,Takayuki Katsuyama,Mariko Takano-Narazaki,Yoshinori Matsumoto,Nao Oguro,Nobuyuki Yajima,Yuichi Ishikawa,Natsuki Sakurai,Chiharu Hidekawa,Ryusuke Yoshimi,Takanori Ichikawa,Dai Kishida,Yasuhiro Shimojima,Jun Wada,Noriaki Kurita
OBJECTIVES There is a high prevalence of burnout among rheumatologists. Grit, which is defined as possessing perseverance and a passion to achieve long-term goals, is predictive of success in many professions; however, whether grit is associated with burnout remains unclear, especially among academic rheumatologists, who have multiple simultaneous responsibilities. Thus, the purpose of this study was
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Mind the Gap: A Longitudinal Analysis of the Experiences of Adolescents and Parents in a Rheumatology Transition Clinic. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-05-25 Molly J Dushnicky,Claire Fine,Tania Cellucci,Stephanie Garner,Liane Heale,Mark Matsos,Karen A Beattie,Michelle Batthish
BACKGROUND The transition from pediatric to adult care is a critical time when adolescent patients and their families face many challenges. This period can be associated with an increase in disease-related morbidity and mortality. The aim of our study is to identify gaps in transition-related care to help guide areas for improvement. METHODS Patients (14-19 years) with juvenile idiopathic arthritis
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Clinical Characteristics and Outcomes of Mexican Patients With Behçet’s Syndrome JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-05-12 Andrea Hinojosa-Azaola, Isabela Ramírez-Mulhern, Ana Figueroa-Pariente, Eduardo Martín-Nares
Objective The aim of this study was to describe the clinical characteristics and outcomes of Mexican patients with Behçet syndrome (BS) from a single center. Methods This medical records review study included patients with established BS diagnosis, followed up in a tertiary care center in Mexico City from 2000 to 2020. Demographics, clinical characteristics, laboratory and imaging studies, disease
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A Randomized, Double-Blind, Placebo-Controlled Phase 2a Study of Tildrakizumab Efficacy and Safety in Patients With Active Ankylosing Spondylitis JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-05-10 Eric Peters, Richard C. Chou, Stephen J. Rozzo, Siu-Long Yao, Ferran José García Fructuoso
Objective Tildrakizumab is an anti-interleukin-23p19 monoclonal antibody approved to treat moderate to severe plaque psoriasis. This study evaluated the efficacy and safety of tildrakizumab in patients with ankylosing spondylitis (AS). Methods In this randomized, double-blind, parallel-group, multinational trial (clinicaltrials.gov NCT02980705), patients with active AS, according to modified New
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Patterns of Relapse and Complications of Immunoglobulin G4–Related Disease JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-05-09 Jie-Ying Kowa, Tae Kyoung Kim, Korosh Khalili, Khaled Y. Elbanna
Background Immunoglobulin G4–related disease (IgG4-RD) is a multisystemic fibroinflammatory condition potentially resulting in organ dysfunction. We aimed to evaluate imaging characteristics of disease relapse and complications in this cohort of patients. Methods This was a cohort study of IgG4-RD patients imaged between 2010 and 2020. Radiological manifestations of disease activity (remission/stability
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Isolated Superior Mesenteric Artery Vasculitis as a Cause of Abdominal Pain JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-05-09 Hirotaka Yamamoto, Yoshinori Taniguchi
This manuscript demonstrates that although isolated superior mesenteric artery vasculitis that also could be called as localized vasculitis of the gastrointestinal tract was rare entity, it is so significant as differential diagnosis of abdominal pain in addition to idiopathic dissection, infective arteritis, and lymphoma. This case should remind readers to consider isolated superior mesenteric artery
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Patterns of Involvement of the Hand Joints in Classical Rheumatoid Arthritis JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-05-09 Ronald J. Anderson, Jing Cui, Michael E. Weinblatt, Daniel H. Solomon, Chinmayi Naik, Nancy A. Shadick
Background Symmetrical involvement of the hand joints is described as characteristic of rheumatoid arthritis (RA). Quantitative data on specific patterns of involvement are lacking. Objective The Brigham Rheumatoid Arthritis Sequential Study was created for observational studies of patients with RA and afforded a unique opportunity to answer these questions. Methods Of 1598 subjects in the Brigham
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Acute Brain Infarction in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: A Korean Single-Center Study JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-05-09 Jang Woo Ha, Joonnyung Heo, Jung Yoon Pyo, Sung Soo Ahn, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee
Objectives This study investigated the clinical and radiological features of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) patients with acute brain infarction, using a cohort of Korean patients with AAV. Methods This study included 263 patients with AAV. Acute brain infarction was defined as infarction that occurred within 7 days or less. The brain territories affected by
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Clinical Image: Histoplasmosis Mimicking Granulomatosis With Polyangiitis in HIV Patient. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-04-28 Fabio Torres-Saavedra,Lina Leon-Sierra
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A Case of Statin-Associated Immune-Mediated Necrotizing Myopathy. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-04-28 Dachen Zuo
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Learn Labial Salivary Gland Biopsy Online. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-04-27 Robert W Ike,Sara S McCoy
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Risk Factors for Relapse and/or Prolonged Glucocorticoid Therapy in Polymyalgia Rheumatica: Multicenter Study in 185 Patients JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-04-26 Juan Pablo Vinicki, Oscar Gut, María del Rosario Maliandi, Jose Luis Velasco Zamora, Miguel Linarez, Maria Alejandra Cusa, Julio Got, Maria Andrea Spinetto, Adrian Jorge Estevez, Alejandro Brigante, Ana Carolina Curti, Ana Carolina Costi, Javier Cavallasca
Background In polymyalgia rheumatica (PMR) relapses and long-term GC dependency are common. We assessed risk factors for higher relapse rate and/or prolonged glucocorticoid therapy in PMR patients. Methods A multicenter and observational study (chart review) of PMR patients seen between 2006 and 2021 who had at least a 3-month follow-up period after starting GCs was performed. Results were expressed
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Disease-Modifying Antirheumatic Drug Use and Its Effect on Long-term Opioid Use in Patients With Rheumatoid Arthritis JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-04-26 Akhil Sood, Yong-Fang Kuo, Jordan Westra, Mukaila A. Raji
Background/Objectives The prevalence of chronic pain is high in patients with rheumatoid arthritis (RA), increasing the risk for opioid use. The objective of this study was to assess disease-modifying antirheumatic drug (DMARD) use and its effect on long-term opioid use in patients with RA. Methods This cohort study included Medicare beneficiaries with diagnosis of RA who received at least 30-day
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Risk Factors and Clinical Outcomes Associated With Sarcopenia in Rheumatoid Arthritis: A Systematic Review and Meta-analysis JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-04-26 Keith Tam, Matthew Wong-Pack, Theodore Liu, Jonathan Adachi, Arthur Lau, Jinhui Ma, Alexandra Papaioannou, Isabel B. Rodrigues
Sarcopenia is underrecognized in patients with rheumatoid arthritis (RA). Risk factors of sarcopenia and its impact on outcomes in RA patients are relatively unknown. We conducted a systematic review to identify factors and outcomes associated with sarcopenia in RA. We conducted this review according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 guidelines. We
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Predictive Factors of Hospital-Acquired Bacterial Infections in Patients With Systemic Lupus Erythematosus JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-04-26 Mauricio Restrepo-Escobar, Paula A. Granda-Carvajal, Daniel C. Aguirre-Acevedo, Fabián Jaimes, Gloria M. Vásquez
Objective We aimed to identify the predictive factors of hospital-acquired bacterial infections in patients with systemic lupus erythematosus (SLE). Methods This chart review study included patients with SLE who were hospitalized between 2009 and 2020 for reasons other than infection. The outcome was defined as any infection confirmed using any bacterial isolation method or diagnosed by treating
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The Mushroom Femoral Head in Legg-Calvé-Perthes Disease. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-04-26 Eaman Alhassan,Stratos Christianakis
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Gastrointestinal Behçet Disease Secondary to Myelodysplastic Syndrome. JCR: J. Clin. Rheumatol. (IF 3.4) Pub Date : 2023-04-26 Kai Shen,Chenlu Yang