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Antimicrobial resistance in ocular infection: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-03-17 Maria Cabrera-Aguas, Ngozi Chidi-Egboka, Himal Kandel, Stephanie L. Watson
Antimicrobial resistance (AMR) is a global public health threat with significant impact on treatment outcomes. The World Health Organization's Global Action Plan on AMR recommended strengthening the evidence base through surveillance programs and research. Comprehensive, timely data on AMR for organisms isolated from ocular infections are needed to guide treatment decisions and inform researchers and
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Assessing the impact of COVID‐19 on diabetic retinopathy in Fiji: A 5‐year review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-03-12 Subash Bhatta, Nayana Pant, Telaite B. Keteca
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Women in ophthalmology Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-03-08 Victoria A. Cartwright, Justine R. Smith
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest.
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Correlation of structure with function: The role of optical coherence tomography in neuro‐ophthalmology Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-03-08 Celia Chen
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest.
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Management of iridocorneal endothelial syndrome from a corneal and glaucoma perspective Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-03-01 Graham A. Lee
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Five-year changes in macular thickness in the elderly population: A cohort study Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-25 Hassan Hashemi, Mehdi Khabazkhoob, Samira Heydarian, Mohammad Hassan Emamian, Akbar Fotouhi
The aim of this study is to determine the 5-year changes in macular thickness and related factors.
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A novel genomic rearrangement on chr19q13.42 leads to PRPF31‐associated retinitis pigmentosa Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-27 Qingxiang Lu, Jingye Yang, Yu Xiong, Xiaoyan Zhu, Miao Zhang, Ding'an Zhou
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest.
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Incidence of liquefied after‐cataract and interval from cataract surgery in eyes undergoing laser capsulotomy Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-26 Minh Duong, Keith Ong
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Myopia progression following 0.01% atropine cessation in Australian children: Findings from the Western Australia – Atropine for the Treatment of Myopia (WA‐ATOM) study Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-24 Samantha Sze‐Yee Lee, Vinay Kumar Nilagiri, Gareth Lingham, Magdalena Blaszkowska, Paul G. Sanfilippo, Maria Franchina, Antony Clark, David A. Mackey
BackgroundA rebound in myopia progression following cessation of atropine eyedrops has been reported, yet there is limited data on the effects of stopping 0.01% atropine compared to placebo control. This study tested the hypothesis that there is minimal rebound myopia progression after cessation of 0.01% atropine eyedrops, compared to a placebo.MethodsChildren with myopia (n = 153) were randomised
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Insights into the diagnosis and management of sarcoid uveitis: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-22 Priya D. Samalia, Lyndell L. Lim, Rachael L. Niederer
Sarcoidosis is a leading cause of non‐infectious uveitis that commonly affects middle‐aged individuals and has a female preponderance. The disease demonstrates age, sex and ethnic differences in clinical manifestations. A diagnosis of sarcoidosis is made based on a compatible clinical presentation, supporting investigations and histologic evidence of non‐caseating granulomas, although biopsy is not
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Social determinants of health and health disparities in glaucoma: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-22 Kaela Acuff, Jo‐Hsuan Wu, Varsha Varkhedi, Sally L. Baxter
Social determinants of health and barriers to care can significantly impact patients' access to glaucoma care and treatment, resulting in disparities within disease presentation, progression, management, and treatment outcomes. The widespread adoption of electronic health record systems has allowed researchers and clinicians to further explore these relationships, identifying factors such as race,
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Management of iridocorneal endothelial syndrome from a corneal and glaucoma perspective: Response Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-21 Philipp K. Roberts, Elsie Chan, Damien G. Harkin, Mark Daniell
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Causes and management of sight threatening complications of dermal filler injections: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-21 Verona E. Botha, Elizabeth A. Insull
Injectable dermal fillers continue to increase in popularity in aesthetic medicine. Although rare, vision loss secondary to filler injections is a devastating complication associated with a poor visual prognosis. The mechanism for vision loss is thought to be related to retrograde embolization of the dermal filler from peripheral vessels in the face into the ophthalmic arterial system. Early recognition
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Current understanding of subclinical diabetic retinopathy informed by histology and high-resolution in vivo imaging Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-16 Martin Hein, Hassanain Qambari, Dong An, Chandrakumar Balaratnasingam
The escalating incidence of diabetes mellitus has amplified the global impact of diabetic retinopathy. There are known structural and functional changes in the diabetic retina that precede the fundus photography abnormalities which currently are used to diagnose clinical diabetic retinopathy. Understanding these subclinical alterations is important for effective disease management. Histology and high-resolution
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Gender differences in retinal diseases: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-13 Anne Tillmann, Lala Ceklic, Chantal Dysli, Marion R. Munk
Gender medicine is a medical specialty that addresses gender differences in health and disease. Traditionally, medical research and clinical practice have often been focused on male subjects and patients. As a result, gender differences in medicine have been overlooked. Gender medicine considers the biological, psychological, and social differences between the genders and how these differences affect
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Ophthalmic sequelae of prematurity in late childhood and adulthood: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-09 Rachel A. Downes, Aleksandra V. Rachitskaya
Advances in the care of premature infants have resulted in unprecedented rates of survival of these infants into adulthood, including those born at very low gestational ages. Ophthalmologists have historically followed premature infants to assess for the presence of and potential need for treatment of retinopathy of prematurity. However, a growing body of literature suggests that the ophthalmic consequences
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The bright future for Clinical and Experimental Ophthalmology in rapidly changing times in scientific publication Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-02-05 Michael Goggin, Fred K. Chen
CONFLICT OF INTEREST STATEMENT Neither author has any conflict of interest regarding the subject matter of this editorial.
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Circular RNA expression profile and functional analysis of circUvrag in light-induced photoreceptor degeneration Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-28 Kangjie Kong, Xinyi Ding, Yingchao Wang, Sisi Xu, Gang Li, Xin Wang, Meng Zhang, Yingqin Ni, Gezhi Xu
Circular RNAs (circRNAs) are implicated in retinal pathophysiology; however, their expression profiles and functions in photoreceptor apoptosis are largely unknown. We explored circRNA-expression profiles and circUvrag (host gene: Uvrag, ultraviolet radiation resistance associated gene) function in light-induced photoreceptor apoptosis.
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Choroidal signal hypertransmission on optical coherence tomography imaging: Association with development of geographic atrophy in age-related macular degeneration Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-29 Zhichao Wu, Jan H. Terheyden, Lauren A. B. Hodgson, Robyn H. Guymer
To examine the association between large choroidal signal hypertransmission ≥250 μm (LHyperT) on optical coherence tomography (OCT) with the risk of developing geographic atrophy (GA) and compare this risk with those associated with nascent geographic atrophy (nGA).
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Disease burden, risk factors, and temporal trends of eye cancer: A global analysis of cancer registries Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-28 Junjie Huang, Sze Chai Chan, Samantha Ko, Veeleah Lok, Lin Zhang, Xu Lin, Don Eliseo Lucero-Prisno, Wanghong Xu, Zhi-Jie Zheng, Edmar Elcarte, Mellissa Withers, Martin C. S. Wong
This study aims to investigate the global disease burden, risk factors, and temporal trends of eye cancer by sex and age group.
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Infectious keratitis following corneal transplantation: A long-term cohort study Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-24 Ian Ittah-Cohen, M. Juliette Knoeri, Tristan Bourcier, Lilia Merabet, Nacim Bouheraoua, Vincent M. Borderie
To assess the long-term incidence and risk factors for post-keratoplasty infectious keratitis (IK), associated ocular pathogens, and antibiotic resistance profiles.
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Global retinoblastoma studies: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-23 Vijitha S. Vempuluru, Arpita Maniar, Swathi Kaliki
In the current era of global health awareness for retinoblastoma (RB), the challenge that lies ahead of us is providing optimal care for children affected with RB in underdeveloped nations. The understanding of similarities and disparities between various nations across the world aids in achieving comparable outcomes. With dissolving geographic barriers and evolving collaboration, global collaborative
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Managing the apparently blind child presenting in the first year of life: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-19 Kate E. Leahy, Edward Lo-Cao, Robyn V. Jamieson, John R. Grigg
Severe vision impairment and blindness in childhood have a significant health burden on the child, family and society. This review article seeks to provide a structured framework for managing the apparently blind child presenting in the first year of life, starting from a comprehensive history and examination. Different investigation modalities and the increasingly important role of genetics will also
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The status of women in academic ophthalmology: Authorship of papers, presentations, and academic promotions Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-12 Vasiliki P. Giannakakos, Misha Syed, Susan M. Culican, Jamie B. Rosenberg
As the field of ophthalmology has evolved in the last several decades, so has the gender distribution of ophthalmologists. We conducted a narrative review to further characterise the status of women in the realm of publication, presentations, editorial positions, grants, academic promotion, and financial compensation. While the proportion of women publishing, presenting, and filling academic and editorial
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Adult stem cells in the eye: Identification, characterisation, and therapeutic application in ocular regeneration – A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-12 Yuting Xiao, Charles N. J. McGhee, Jie Zhang
Adult stem cells, present in various parts of the human body, are undifferentiated cells that can proliferate and differentiate to replace dying cells within tissues. Stem cells have specifically been identified in the cornea, trabecular meshwork, crystalline lens, iris, ciliary body, retina, choroid, sclera, conjunctiva, eyelid, lacrimal gland, and orbital fat. The identification of ocular stem cells
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Pregnancy and the eye: What do we need to watch out for? A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-12 Reema Madike, Sudha Cugati, Queena Qin, Celia Chen
Pregnancy causes changes in all body systems, including the eye. The eye can undergo physiological and pathological changes in pregnancy. Some changes exacerbate pre-existing eye conditions while other conditions manifest for the first-time during pregnancy. Early recognition and management are essential to prevent sight threatening complications. In addition, some obstetric complications can be associated
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Recent advances in the use of optical coherence tomography in neuro-ophthalmology: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-12 Jasmine Yaowei Ge, Zhen Ling Teo, Jing Liang Loo
Optical coherence tomography (OCT) is an in vivo imaging modality that provides non-invasive, high resolution and fast cross-sectional images of the optic nerve head, retina and choroid. OCT angiography (OCTA) is an emerging tool. It is a non-invasive, dye-free imaging approach of visualising the microvasculature of the retina and choroid by employing motion contrast imaging for blood flow detection
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Optical coherence tomography biomarkers in early and intermediate age-related macular degeneration: A clinical guide Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-12 Lourdes Vidal-Oliver, Elena Montolío-Marzo, Roberto Gallego-Pinazo, Rosa Dolz-Marco
Advanced forms of age-related macular degeneration (AMD), characterised by atrophic and neovascular changes, are a leading cause of vision loss in the elderly population worldwide. Prior to the development of advanced AMD, a myriad of risk factors from the early and intermediate stages of AMD have been published in the scientific literature over the last years. The ability to precisely recognise structural
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Ultrasound biomicroscopy in the management of complex cataract and intraocular lens: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-12 Nicole S.W. Chan, Jane S. Lim, Lakshmanasamudram S. Mohanram, Soon-Phaik Chee
Ultrasound biomicroscopy (UBM) is an invaluable investigation for imaging anterior segment structures. Although it is operator-dependent and time consuming, unlike optical-based imaging techniques, it is able to image structures posterior to the iris, such as the zonules, ciliary body and part of the pars plana. It is especially useful in advanced cataracts, traumatic cataracts, subluxed lenses, posterior
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Tracing the barriers to decarbonising ophthalmology: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-11 Lydia Lam, Darren Bradbrook, Jesse Gale
As climate change demands increasingly urgent mitigation of greenhouse gas emissions, the health sector needs to do its part to decarbonise. Ophthalmologists share concerns about climate change and seek opportunities to reduce their environmental impact. When measuring the footprint of ophthalmology, major contributions are from patient travel to clinics, and from the large amounts of single-use disposable
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How does ocular graft-versus-host disease fit under the dry eye umbrella? A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2024-01-10 Nicole B. Kantor, Arianna Tovar, Trent Wang, Anat Galor
Graft-versus-host disease (GVHD) is a systemic disease that can affect multiple organs as a consequence of an allogeneic haematopoietic stem cell transplant. One organ system that is often affected in GVHD is the eyes. Ocular GVHD (oGVHD) may involve various structures within the eye including the lacrimal glands, eyelids, conjunctiva, cornea, and nasolacrimal ducts, and is a source of morbidity in
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Lipids from ocular meibum and tears may serve as biomarkers for depression and post-traumatic stress disorder Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-12-26 Ashlyn A. Gary, Amanda Prislovsky, Arianna Tovar, Elyana Locatelli, Elizabeth R. Felix, Daniel Stephenson, Charles E. Chalfant, James Lai, Colin Kim, Nawajes Mandal, Anat Galor
There is a need to develop biomarkers for diagnosis and prediction of treatment responses in depression and post-traumatic stress disorder (PTSD).
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Insulin resistance is associated with the presence and severity of retinopathy in patients with type 2 diabetes Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-12-22 Yu-Xin Xu, Sheng-Dan Pu, Yi-Tong Zhang, Xue-Wei Tong, Xiao-Tong Sun, Yong-Yan Shan, Xin-Yuan Gao
To assess the relationship between novel insulin resistance (IR) indices and the presence and severity of diabetic retinopathy (DR) in patients with type 2 diabetes.
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Epiretinal membrane in uveitis: Rate, visual prognosis, complications and surgical outcomes Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-12-18 Aaron Yap, Lucy M. Lu, Joanne L. Sims, Sarah Welch, Rachael L. Niederer
Epiretinal membrane (ERM) is a common finding in patients with uveitis that contributes to visual impairment. We describe the long-term visual acuity (VA) and morphometric progression in patients with uveitis and epiretinal membrane (ERM).
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Impact of COVID-19 on ophthalmic medical access during successive waves: Demographics, disease factors, and wave locations Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-12-13 Kwanghyun Lee, Young Min Park, Jung-Kyu Choi, Jaekwang Lee
The coronavirus disease (COVID-19) pandemic significantly impacted medical care, including ophthalmology. This study aimed to identify factors associated with reduced ophthalmic medical access during the pandemic.
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Systematic review and appraisal of quality, definitions and treatment recommendations of clinical guidelines for glaucoma suspects Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-12-13 Zhichao Wu, Senuri Karunaratne, Ghee Soon Ang, Keith R. Martin, Laura E. Downie
To appraise the quality of clinical practice guidelines for glaucoma suspects, and to assess their consistency for how a ‘glaucoma suspect’ is defined and their recommendations for treatment initiation for such individuals.
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Unilateral intraindividual comparison and bilateral performance of a monofocal spherical and diffractive extended depth of field intraocular lens mix-and-match approach Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-12-04 Jascha A. Wendelstein, Marina Casazza, Sophia Reifeltshammer, Kamran Riaz, Seth Pantanelli, Siegfried Mariacher, Theo G. Seiler, Thomas Kohnen, Matthias Bolz
To evaluate the intraindividual visual performance of a spherical and extended depth of field (EDOF) IOL used in a mix-and-match approach.
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Ophthalmic surgery in patients with only one seeing eye: Only eye study 4 (OnES 4). Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-28 Shenouda Girgis,Jonathan P Whyte,Peter Shah,Graham A Lee
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Uveitis masquerade syndromes: An approach to diagnosis Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-23 Ming Lee Lin, Anthony J. Hall
Uveitis masquerade syndromes are a diverse group of clinical entities which mimic conventional immune-mediated uveitis due to the presence of inflammatory signs but are resistant to anti-inflammatory therapy. Misdiagnosis hinders appropriate management in these conditions and may result in poor outcomes. This review discusses commonly encountered neoplastic and non-neoplastic disease processes that
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Evaluation of ocular surface following PreserFlo Microshunt implantation: Functional outcomes and quality of life Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-20 Gloria Gambini, Matteo Mario Carlà, Federico Giannuzzi, Alfonso Savastano, Tomaso Caporossi, Antonio Baldascino, Danilo Iannetta, Lorenzo Vielmo, Stanislao Rizzo
This study aimed to evaluate the impact of PreserFlo Microshunt on the ocular surface, focusing on both objective and subjective parameters.
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Treatments for geographic atrophy are on our doorstep: Are we ready? Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-12 Amy Cohn, Robyn H. Guymer
CONFLICT OF INTEREST STATEMENT AC: speaker fees: Bayer, Novartis and Roche. Travel fees: Bayer. RHG: Advisory board, consulting fees—Apellis, Bayer, Novartis and Roche/Genentech.
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Welcoming artificial intelligence into ophthalmology Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-12 Justine R. Smith
CONFLICT OF INTEREST STATEMENT Justine R. Smith has no conflicts of interest to declare.
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Uptake of paediatric vision screening in Queensland, Australia: An analysis of socioeconomic factors. Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-14 Ye Li,Shelley Duffy,Sagen Wilks,Rachel Keel,Rachael Beswick,Shuan Dai
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Only Eye Study 5 (OnES 5): A quantitative study of patient experiences undergoing surgery in their only seeing eye. Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-14 Eagle D Ngo,Graham A Lee,Shenouda Girgis,Peter Shah
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Incidence and associations of vitreous haemorrhage in proliferative diabetic retinopathy. Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-14 Shenouda Girgis,Helen Hyun-Jin Do,Belinda Leong,Gerald Liew
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Keratoconus in Down syndrome: Prevalence, risk factors, severity and corneal tomographic characteristics Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-14 Joyce J. Mathan, Akilesh Gokul, Samantha K. Simkin, Jay J. Meyer, Charles N. J. McGhee
This study investigated the prevalence, risk factors and severity of corneal tomographic features of keratoconus in Down syndrome (DS). Additionally, previous studies indicate anomalous corneal features in DS, without keratoconus, this study characterised corneal features in DS without keratoconus.
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Dry eye symptoms and signs in United States Gulf War era veterans with myalgic encephalomyelitis/chronic fatigue syndrome Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-12 Victor Sanchez, Colin K. Kim, Elyana V. T. Locatelli, Adam K. Cohen, Kimberly Cabrera, Kristina Aenlle, Nancy G. Klimas, Robert O'Brien, Anat Galor
To examine ocular symptoms and signs of veterans with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) diagnosis, ME/CFS symptoms, and controls.
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Assessing the carbon footprint of fluorinated gases in vitreoretinal surgery. Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-11-10 Yuqing Lu,Doron Hickey,Penelope Allen,Thomas L Edwards
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Predicting ophthalmic clinic non-attendance using machine learning: Development and validation of models using nationwide data Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-10-27 Finley Breeze, Ruhella R. Hossain, Michael Mayo, James McKelvie
Ophthalmic clinic non-attendance in New Zealand is associated with poorer health outcomes, marked inequities and costs NZD$30 million per annum. Initiatives to improve attendance typically involve expensive and ineffective brute-force strategies. The aim was to develop machine learning models to accurately predict ophthalmic clinic non-attendance.
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Six-year analysis of the pathogenic spectrum, risk factors, and prognosis of non-traumatic fungal keratitis in Northern China. Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-10-24 Yani Wang,Huabo Chen,Fangyuan Wang,Yanling Dong
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Twenty-four-month real-life treatment outcomes of polypoidal choroidal vasculopathy versus type 1 macular neovascularization in Caucasians Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-10-23 Matteo Airaldi, Alessandro Invernizzi, Vuong Nguyen, Stela Vujosevic, Federico Ricci, Pietro Monaco, Marco Nassisi, Daniel Barthelmes, Mark Gillies, Francesco Viola
To compare 24-month real-world outcomes of Vascular Endothelial Growth Factor (VEGF) inhibitors for Polypoidal Choroidal Vasculopathy (PCV) and type 1 Macular Neovascularization (MNV) in a Caucasian population.
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If you like it, should you really put a ring in it? Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-10-06 Gerard Sutton, Chris Hodge
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest.
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Online uveitis support groups: A modern day survival guide Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-10-06 Ming Lee Lin
CONFLICT OF INTEREST STATEMENT The author declares no conflict of interest.
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Increasing ocular syphilis and syphilis notifications in Australia and the state of Victoria between 2017 and 2022. Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-10-06 Sachin Phakey,Jasmine Lichtenstein,Lyndell L Lim
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Next-generation sequencing of uveal melanoma with clinical and histological correlations: Prognostic value of new mutations in the PI3K/AKT/mTOR pathway Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-10-06 Manuel Pérez-Pérez, Alessandro Agostino, Carmen García de Sola-Llamas, Michael Ruvolo, Angel Vilches-Arenas, M. Isabel Relimpio-López, Francisco Espejo-Arjona, Laura Macías-García, Manuel De Miguel-Rodríguez, Antonio García-Escudero, Miguel A. Idoate, Juan J. Ríos-Martín
Uveal melanoma (UM) is the eye's most common primary malignancy and there are no effective therapies for disseminated disease. It is important to try to know the patient's prognosis. The aim of this study was to reflect genetic variants, studied using NGS, of a series of 69 cases of UM and its correlation with histopathology and clinical progression.
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Clinical outcomes of fiducial-free proton beam therapy in Asian patients with uveal melanoma. Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-09-24 Hung-Da Chou,Wing-Keen Yap,Chun-Chieh Wang,An-Ning Chao
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Treatment of dry age-related macular degeneration: A review Clin. Exp. Ophthalmol. (IF 4.0) Pub Date : 2023-09-22 Shenouda Girgis, Lawrence R. Lee
Age-related macular degeneration is a global disease with a significant societal impact. The advent of anti-vascular endothelial growth factor therapy (anti-VEGF) has revolutionised the treatment of neovascular age-related macular degeneration (nAMD). Dry age-related macular degeneration (dAMD) is being investigated for possible therapeutic options. The therapeutic categories undergoing clinical trials