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Preserving visual acuity: a compelling 12-year case study of controlling neovascular age-related macular degeneration BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-18 Rita O. Tomás, António Campos, Nuno Oliveira, Pedro Soares, João P. Sousa
In neovascular age-related macular degeneration (nAMD) trials, anti-VEGF injection frequency decreases after the first year, while outcomes remain primarily related to the number of injections. To the best of our knowledge, there are no reports of maintaining the best corrected visual acuity (BCVA) for more than 7 years in extension studies. To report a 12-year follow-up of a real-world case of nAMD
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Minimally invasive micro sclerostomy (MIMS) procedure in the treatment of open-angle glaucoma BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-18 Lilit Voskanyan, Iqbal Ike K. Ahmed, Assaf Gershoni, Edward Barayev, Vahan Papoyan, Astghik Ghazaryan, Oren Bar-Ilan, Alon Zahavi, Yoseph Glovinsky, Noa Geffen
To evaluate the safety and efficacy of the Minimally Invasive Micro Sclerotomy (MIMS) procedure in the management of uncontrolled open-angle glaucoma. A prospective, open-label, single-arm clinical evaluation with intra-subject comparisons performed at the Ophthalmologic Center after S.V. Malayan, Yerevan, Armenia. Included were adults with primary open-angle glaucoma (OAG) (N = 114) or exfoliative
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Artificial intelligence in age-related macular degeneration: state of the art and recent updates BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-15 Emanuele Crincoli, Riccardo Sacconi, Lea Querques, Giuseppe Querques
Age related macular degeneration (AMD) represents a leading cause of vision loss and it is expected to affect 288 million people by 2040. During the last decade, machine learning technologies have shown great potential to revolutionize clinical management of AMD and support research for a better understanding of the disease. The aim of this review is to provide a panoramic description of all the applications
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Effect of topical bromfenac on intraretinal cystoid lesion in simultaneous cataract and idiopathic epiretinal membrane surgery BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-15 EunAh Kim, Han Jo Kwon, Sung Who Park, Iksoo Byon
To investigate the effect of topical nonsteroidal anti-inflammatory drugs (NSAIDs,) bromfenac on the intraretinal cystic lesions (IRC) when performing simultaneous cataract and idiopathic epiretinal membrane (iERM) surgery. This study included patients with iERM who had been followed up for 6 months after vitrectomy, membrane removal, and concurrent cataract surgery. Eyes were treated with topical
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Effect of silicone oil versus gas tamponade on macular layer microstructure after pars plana vitrectomy for macula on rhegmatogenous retinal detachment BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-14 Abdulaziz Mohammed Al-Shehri, Saud Aljohani, Khalid Abdulaziz Aldihan, Musa Johaiman Alrashedi, Saad Alrasheed, Patrik Schatz
To analyze structural changes in the macular retinal layers and sub-foveal choroidal thickness (SFCT) in eyes after macula-on rhegmatogenous retinal detachment (RRD) repair by pars plana vitrectomy with either silicone oil (SO) or gas tamponade, and the effect of these changes on visual acuity. Retrospective study which included 26 eyes in the SO Group and 32 in the Gas Group. Optical coherence tomography
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Long-term outcomes of anti-vascular endothelial growth factor therapy with and without posterior scleral reinforcement on myopic maculopathy in myopic choroidal neovascularization eyes BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-13 Meng-Tian Kang, Ningli Wang, Wenjun Xu, Mayinuer Yusufu, Wu Liu, Jiaxin Tian, Yue Qi
Anti-vascular endothelial growth factor (anti-VEGF) therapy is used for myopic choroidal neovascularization (mCNV). Patchy chorioretinal atrophy (pCRA) enlargement has been reported in mCNV cases associated with vision loss. Our aim was to compare the long-term effectiveness of anti-VEGF therapy alone versus anti-VEGF followed by posterior scleral reinforcement (PSR) in controlling myopic maculopathy
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Interface fluid syndrome caused by the corneal perforation injury after small incision lenticule extraction: a case report BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-13 Xu Jing, Li Congxin, Zhang Xiaoyan, Yuan Yue, Li Jiao, Zu Peipei, Wang Yirong, Wen Ying, Bi Hongsheng
To report a case of interface fluid syndrome (IFS) following traumatic corneal perforation repair after small incision lenticule extraction (SMILE). A 23-year-old woman, with a past history of SMILE, was struck in the left eye with a barbecue prod and subsequently underwent corneal perforation repair at local hospital. Primary wound repaired with a single 10 − 0 nylon suture at the area of leakage
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Vogt-Koyanagi-Harada disease developed during chemotherapy for Hodgkin lymphoma: a case report BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-13 Mutsumi Koyama, Euido Nishijima, Takaya Honda, Chizuru Gonmori-Ohta, Takeaki Sasamoto, Katsuyuki Tanaka, Akira Watanabe, Tadashi Nakano, Masaharu Akiyama
Ocular manifestations are known for non-Hodgkin lymphoma, but are rare for Hodgkin lymphoma. We report a case of Vogt-Koyanagi-Harada (VKH) disease presenting as serous retinal detachment and uveitis in both eyes in a child undergoing chemotherapy for Hodgkin lymphoma. The patient was a 7-year-old boy with stage IIB Hodgkin lymphoma (nodular lymphocyte predominant type) who was undergoing chemotherapy
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Strabismus management in retinoblastoma survivors BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-13 Babak Masoomian, Carol L. Shields, Hamid Riazi Esfahani, Atefeh Khalili, Fariba Ghassemi, Pukhraj Rishi, Mohammad Reza Akbari, Masoud Khorrami-Nejad
To report the result of strabismus surgery in eye-salvaged retinoblastoma (Rb) patients. A retrospective case series including 18 patients with Rb and strabismus who underwent strabismus surgery after completing tumor treatment by a single pediatric ophthalmologist. A total of 18 patients (10 females and 8 males) were included with a mean age of 13.3 ± 3.0 (range, 2–39) months at the time tumor presentation
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Short-term effect of intravitreal dexamethasone implant in refractory diabetic macular edema BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-11 Jazmín Baca Moreno, David Berrones Medina, María Fernanda Rosellón-Escobar, José Gerardo García-Aguirre
To evaluate the short-term effects (hours-days) of intravitreal dexamethasone implant (IDI) in eyes with diabetic macular edema (DME) refractory to anti-vascular endothelial growth factor (VEGF) injections. This was a prospective, single-arm, interventional clinical series. Eyes with DME and 3–9 injections of ranibizumab without a good response were included. Patients underwent a single IDI. Best-corrected
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Sling for the sling: a new technique for long-term correction of severe congenital ptosis BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-07 Ahmed N. Kotb, Noha M. Soliman, Ahmer Raza, Noran A. Nour, Hala K. Mattout
Severe congenital ptosis poses a complex challenge for oculoplastic surgeons, requiring meticulous surgical intervention to restore eyelid function and improve aesthetic outcomes mainly by using frontalis sling approach. A crucial issue in frontalis sling surgeries is the sustainability of effect. This retrospective study reports the outcomes of two surgical techniques for treating severe congenital
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Retinochoroiditis secondary to Rickettsia typhi infection: a case report BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-07 Joanne Makhoul, Yael Ben-Arie-Weintrob, Dror Ben Ephraim Noyman
To report a case of unusual presentation of retinochoroiditis caused by Rickettsia typhi in a patient without prior uveitis. In this case, we describe a 24-year-old male soldier with no previous eye disease, who was referred to our ophthalmology department due to bilateral retinochoroiditis and vitritis. The patient initially presented with a paracentral scotoma in his right eye persisting for 7 days
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Measurement of the distance between corneal apex and pupil center in patients following small-incision lenticule extraction or implantable collamer lens implantation and its correlation with the surgical-induced astigmatism BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-07 Yishan Qian, Lan Ding, Yanlan Ding, Lin Jiang, Zesheng Liu, Xingtao Zhou
To investigate the change in the distance between corneal apex and pupil center after small-incision lenticule extraction (SMILE) or implantable collamer lens (ICL) implantation and its correlation with surgical-induced astigmatism (SIA). This study included patients who had undergone SMILE (n = 112) or ICL implantation (n = 110) to correct myopia and myopic astigmatism. The angle kappa was measured
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The effect of polyethylene cover intervention on ocular surface disorder of intensive care unit patients: a systematic review and meta-analysis BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-06 Maryam Askaryzadeh Mahani, Monirosadat Nematollahi, Fatameh Bahramnezhad, Jamileh Farokhzadian
Polyethylene covers have been proven to be effective in protecting the eyes in patients with decreased or disappeared blink reflexes, but their advantages compared to other conventional methods are still unclear. This systematic review and meta-analysis study aimed to elucidate the impact of polyethylene covers in the prevention of ocular surface disease (OSD) in patients admitted to the intensive
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Comparison of bleb morphologies between phacoemulsification combined with Ex-PRESS mini shunt implantation, phacotrabeculectomy and trabeculectomy alone: a two-year retrospective in vivo confocal microscopy study BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-06 Yuqiao Zhang, Chunxin Lai, Suwen Zhao, Ling Li, Xiaoyang Luo, Yanlei Chen, Yongyi Niu, Yongjie Qin, Hongyang Zhang
To compare the bleb morphologies of phacoemulsification combined with Ex-PRESS implantation (Phaco-ExPRESS), phaco trabeculectomy (Phaco-Trab), and trabeculectomy (Trab) in postoperative two years. Patients with primary open-angle glaucoma (POAG) with or without cataracts were included in this study. All patients underwent surgeries of either Phaco-ExPRESS, Phaco-Trab, or Trab. The morphologic structures
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Association between body stature with ocular biometrics and refraction among Chinese preschoolers BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-06 Linling Li, Chimei Liao, Xiaojuan Zhang, Juan Lu, Yangfa Zeng, Min Fu, Decai Wang
To evaluate the association of body stature with ocular biometrics and refraction in preschool children. A cross-sectional, school-based study was conducted in Shenzhen, China. Preschool children aged 3 to 6 from 10 randomly-selected kindergartens were recruited. Ocular biometric parameters, including axial length (AL), anterior chamber depth (ACD), vitreous chamber depth (VCD), corneal radius curvature
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Frosted branch angiitis in a patient with systemic juvenile idiopathic arthritis: a case report BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-05 Jarret L. Garbrecht, Zachary R. Powell, Cynthia K. McClard, Jila Noori
Frosted branch angiitis is a retinal vascular condition that is associated with a viral infection or autoimmune disorders like Crohn’s disease, systemic lupus erythematosus, and Behcet’s disease. Frosted branch angiitis presents with vascular inflammation, retinal edema, and severe retinal vascular sheathing. We present a case of systemic juvenile idiopathic arthritis, an autoinflammatory disease,
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Novel surgical approaches for treating myopic traction maculopathy: a meta-analysis BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-05 Miguel A. Quiroz-Reyes, Erick A. Quiroz-Gonzalez, Miguel A. Quiroz-Gonzalez, Virgilio Lima-Gomez
Myopic traction maculopathy (MTM) is a complication of pathological myopia and encompasses various pathological conditions caused by tractional changes in the eye. These changes include retinoschisis, foveal retinal detachment, and lamellar or full-thickness macular holes (FTMHs). This meta-analysis evaluated the safety and efficacy of novel surgical for treating MTM. To compare the outcomes of different
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Potential causal associations between leisure sedentary behaviors, physical activity, sleep traits, and myopia: a Mendelian randomization study BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-05 Xiao-Bin Zhang, He-He Jiang, Lin-Lin Zhang, Chun-Jing Li, Chen Chen, Meng-Zhen Xing, Yu-Ning Ma, Yu-Xia Ma
Myopia is the most prevalent refractive error and a growing global health concern that significantly affects visual function. Researchers have recently emphasized considerably on the influence of lifestyle on myopia incidence and development. This study investigates the relationship between leisure sedentary behaviors (LSB)/physical activity (PA)/sleep traits and myopia. LSB, PA, and sleep trait-associated
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Dislocation force of scleral flange-fixated intraocular lens haptics BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-05 Spela Stunf Pukl, Martin Kronschläger, Manuel Ruiss, Stéphane Blouin, Emre Rüştü Akcan, Oliver Findl
To measure the dislocation forces in relation to haptic material, flange size and needle used. Hanusch Hospital, Vienna, Austria. Laboratory Investigation. 30 G (gauge) thin wall and 27 G standard needles were used for a 2 mm tangential scleral tunnel in combination with different PVDF (polyvinylidene fluoride) and PMMA (polymethylmethacrylate haptics). Flanges were created by heating 1 mm of the haptic
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Subthreshold micropulse laser therapy for early postoperative macular thickening following surgical removal of epiretinal membrane BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-05 Hongjie Lin, Zijing Huang, Dingguo Huang, Dezhi Zheng, Peimin Lin, Yangxuan Lin, Weiqi Chen
This study aimed to investigate the functional and anatomical outcomes of subthreshold micropulse laser (SMPL) therapy in eyes with early postoperative macular thickening after idiopathic epiretinal membrane (iERM) removal. This was a prospective and interventional study. Forty-eight eyes from 48 patients with macular edema at 1 month after iERM removal were randomly divided into two groups. Patients
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Intrapapillary hemorrhage with adjacent peripapillary subretinal hemorrhage of both eyes after COVID-19 infection: a case report BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-04 Yifan Wang, Hong Chen, Lifei Yuan, Yijia Fan, Yilei Liang, Haiyu Zhang, Ziyao Dang, Lifei Wang
Intrapapillary hemorrhage with adjacent peripapillary subretinal hemorrhage is commonly observed in myopia with tilted optic disc. It presents with typical features on the fundus and follows a self-limiting course. However, due to its complex etiology, clinicians sometimes lack sufficient understanding of it which can easily lead to misdiagnosis or overtreatment. In this case report, we describe a
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Visual outcome of various dose of glucocorticoids treatment in nonarteritic anterior ischemic optic neuropathy– a retrospective analysis BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-04 Fang-Fang Zhao, Yun Chen, Tai-Ping Li, Yun Wang, Hong-Jie Lin, Jian-Feng Yang, Lan Chen, Shao-Ying Tan, Jia-Jian Liang, Ling-Ping Cen
The objective of this investigation was to assess the therapeutic efficacy of distinct glucocorticoid therapy dosages in the management of acute nonarteritic anterior ischemic optic neuropathy (NAION). This retrospective, unmasked, and non-randomized study included a total of 85 patients. The patients were categorized into four groups: Group 1 (control) consisted of 15 patients who did not receive
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Epstein-Barr virus-positive iris diffuse large B-cell lymphoma detected by metagenomic next-generation sequencing BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-04 Xiao-na Wang, Jing Hong, Yong-gen Xu, Pei Zhang, Ying-yu Li, Hong-liang Dou, Hai-ping Li
Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma (DLBCL) is a relatively rare subtype of DLBCL. Herein, we report a case of a patient with EBV-positive iris DLBCL after undergoing penetrating keratoplasty and discuss its possible pathogenesis. A 72-year-old male patient presented to our hospital with progressive blurring of vision in the left eye for the past 4 months. Small white nodular
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Self-supervised pre-training for joint optic disc and cup segmentation via attention-aware network BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-04 Zhiwang Zhou, Yuanchang Zheng, Xiaoyu Zhou, Jie Yu, Shangjie Rong
Image segmentation is a fundamental task in deep learning, which is able to analyse the essence of the images for further development. However, for the supervised learning segmentation method, collecting pixel-level labels is very time-consuming and labour-intensive. In the medical image processing area for optic disc and cup segmentation, we consider there are two challenging problems that remain
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Efficacy of 5-fluorouracil (5-FU) and low molecular weight heparin (LMWH) in high-risk pediatric retinal detachment; randomized clinical trial BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-04 Mohamed Nasr, Ahmed Abdelhadi, Amr Bessa, Tamer Moussa Ibrahim
Pediatric rhegmatogenous retinal detachments (PRRDs) are complex, rare occurrences and are often related to trauma or congenital abnormalities. Children often do not recognize or report symptoms of retinal detachment. Thus at presentation, PRRD is typically advanced often with macular involvement, proliferative vitreoretinopathy (PVR), chronic duration, and poor visual acuity. Because 5-FU and LMWH
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Acute retinal pigment epitheliitis during treatment of hyperprolactinaemia BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-01 Małgorzata Kowalik-Jagodzińska, Karolina Czajor, Anna Turno-Kręcicka
Acute retinal pigment epitheliitis (ARPE) is a rare, idiopathic and self-limiting disease. The article aims to present ARPE in a patient using D2 dopamine receptor agonists for the treatment of hyperprolactinemia. A 28-year-old female during hyperprolactinaemia treatment suffered from a dyschromatopsia and a central visual field defect in the left eye. She noticed a deterioration of vision and discontinued
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Comparison of cognitive workload and surgical outcomes between a three-dimensional and conventional microscope macular hole surgery BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-01 Aditya Kelkar, S. Natarajan, Akshay Kothari, Mounika Bolisetty
Performing a surgical task subjects the surgeon to multitudinal stressors, especially with the newer 3D technology. The quantum of cognitive workload using this modern surgical system in comparison to the Conventional microscope system remains unexplored. We evaluate the surgeon’s cognitive workload and the surgical outcomes of macular hole(MH) surgery performed on a 3D versus a Conventional microscope
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The non-linear relationship between serum albumin and diabetic retinopathy in type 2 diabetes mellitus: a secondary analysis based on a cross-sectional study BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-01 Guo-Qiang Zeng, Yu-Feng Yao, Jian-Bo Zhong, Yi Zhang, Bai-Kang Ye, Xiao-Yan Dou, Li Cai
Most studies had shown a linear relationship between serum albumin (sALB) and the prevalence of diabetic retinopathy (DR). Thus, the purpose of this study is to investigate whether their relationship is non-linear. We included 426 patients with type 2 diabetes who were hospitalized in Guangdong Provincial People’s Hospital from December 2017 to November 2018. The outcome was the prevalence of DR. A
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Study of myopia progression and risk factors in Hubei children aged 7–10 years using machine learning: a longitudinal cohort BMC Ophthalmol. (IF 2.0) Pub Date : 2024-03-01 Wenping Li, Yuyang Tu, Lianhong Zhou, Runting Ma, Yuanjin Li, Diewenjie Hu, Cancan Zhang, Yi Lu
To investigate the trend of refractive error among elementary school students in grades 1 to 3 in Hubei Province, analyze the relevant factors affecting myopia progression, and develop a model to predict myopia progression and the risk of developing high myopia in children. Longitudinal study. Using a cluster-stratified sampling method, elementary school students in grades 1 to 3 (15,512 in total)
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Psychometric assessment of patients with central serous chorioretinopathy and correlation with disease stage and progression: a case control study BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-29 Hinrich J. Hufnagel, Claas Lahmann, Hansjürgen Agostini, Clemens Lange, Laurenz J. B. Pauleikhoff
Central serous chorioretinopathy (CSC) has frequently been associated with increased stress levels as well as an increased prevalence of other psychiatric conditions. This study used standardized psychometric scores to assess stress, depression and anxiety levels of CSC patients and compared them to controls without retinal disease (“healthy”) and with branch retinal vein occlusion (BRVO). Monocentric
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Micropulse transscleral cyclophotocoagulation (MP-CPC): efficacy endpoints for the treatment of refractory paediatric glaucoma - a retrospective case-series BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-28 Nasser Balbaid, Mohammed AlJodai, Ghadeer Fairaq, Maram AlEnzi, Sami AlShahwan
This study evaluates the efficacy and safety of micropulse transscleral cyclophotocoagulation (MP-CPC) in paediatric patients. This retrospective case-series recruited 44 eyes for glaucoma patients who were younger than 17 years and were treated with MP-CPC and followed for at least one year. Pre- and post-intervention intraocular pressure (IOP) was compared out to at least one year postoperatively
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Could driving help us to “see better”? A comparative assessment of saccadic efficiency, visual speed, and attention BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-27 Andrés Gené-Sampedro, Francisco Alonso, Javier Gene-Morales, Pedro Lourenço Monteiro, Sergio A. Useche
This study aimed at comparing drivers’ and non-drivers’ results in the Adult Developmental Eye Movement with Distractors test (ADEMd) and the Useful Field of View test (UFOV). One hundred and twenty Spaniards (mean age 50.90 ± 17.32 years) without eye disease voluntarily participated in this cross-sectional descriptive study. Participants in a single experimental session completed a questionnaire on
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Investigation of alterations in retrobulbar hemodynamics and their correlation with choroidal thickness after strabismus surgery BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-27 Aslihan Uzun, Hilal Altas, Asena Keles Sahin
To evaluate the changes in retrobulbar circulation after strabismus surgery and to assess the relationship of these changes with choroidal thickness (CT). This prospective study included 26 eyes of 26 patients who underwent strabismus surgery and 15 eyes of 15 healthy individuals as control group. The patients who had single horizontal muscle surgery were included in Group 1 (n = 14); and those who
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Outcomes of gonioscopy-assisted transluminal trabeculotomy in primary congenital glaucoma treatment: a retrospective study BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-26 Junyi Lai, Yunsheng Qiao, Chen Tan, Junyi Chen
This retrospective study aimed to evaluate the efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) in Chinese patients with primary congenital glaucoma (PCG) and identify factors influencing surgical success. Fourteen patients (24 eyes) diagnosed with PCG who underwent gonioscopy-assisted transluminal trabeculotomy were recruited, and data on intraocular pressure (IOP), antiglaucoma
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Differences in anterior chamber depth in keratoconus patients with binocular very asymmetry ectasia BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-26 Zizhen Wang, Haowen Ma, Yu Zhang, Yifei Yuan, Yan Liu, Yueguo Chen
To evaluate the difference in anterior chamber depth (ACD) between two eyes among keratoconus patients with binocular very asymmetric ectasia (VAE) and to explore the influencing factors. The corneal curvature and ACD in both eyes of patients with VAE were measured by Sirius (version 3.2, CSO, Italy) at the following points: corneal vertex, maximum curvature (apex), and the 1.5 mm, 2.5 mm, and 3.5 mm
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Clinical performance and shape analysis of trifocal intraocular lenses via scanning electron microscopy BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-26 Kazuya Yamashita, Koji Hayashi, Seiichiro Hata
To evaluate visual performance after implantation of the TFNT (Acrysof Panoptix, Alcon, Fort Worth, Texas, USA) and CNWT (Clareon Panoptix, Alcon, Fort Worth, Texas, USA) intraocular lens (IOL), and compare the lens shape observed by scanning electron microscope (SEM). Eighteen patients (18 eyes) received implantation of the CNWT and Twenty patients (20 eyes) received implantation of the TFNT. Exclusion
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Early choroidal and retinal changes detected by swept-source oct in type 2 diabetes and their association with diabetic kidney disease: a longitudinal prospective study BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-23 Monica Oliveira da Silva, Anne Elise Cruz do Carmo Chaves, Glauber Corrêa Gobbato, Fabio Lavinsky, Daniel Lavinsky
To evaluate structural changes in retina and choroid in patients with type 2 diabetes (T2D) and their association with diabetic kidney disease (DKD). T2D patients with mild or no diabetic retinopathy (DR) were followed for 3 years using structural SS-OCT and OCT angiography (OCT-A) taken every 6 months. Parameters were compared longitudinally and according to the DKD status on baseline. One hundred
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Morphological and functional characteristics of the meibomian gland in pediatric patients with epiblepharon BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-22 Junping Li, Xiaolin Qin, Hong Jiang, Yunan Guo, Xin Liu, Rui Zhang, Lu Jiang, Anshi Du
To observe morphologic and functional changes in meibomian glands in pediatric patients with and without lower eyelid epiblepharon. In this prospective observation study, 55 eyes of 55 patients( 24 males, 31 females; mean age ± SD,9.82 ± 2.59 years; range 6–14 years) and 60 eyes of 60 controls ( 32 males, 28 females; mean age ± SD,10.57 ± 2.75 years; range 6–14 years) were included. The following tests
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Refractive error and vision related quality of life BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-22 Mojtaba Rajabpour, Haleh Kangari, Konrad Pesudovs, Masoud Khorrami-nejad, Saeed Rahmani, Sahar Mohaghegh, Shima Moradnejad
To investigate and compare the vision-related quality of life (QOL) in different types of refractive error (RE). This cross-sectional study was performed on 200 subjects, categorized into four groups of 50 each, consisting of subjects with myopia, hyperopia, astigmatism, and emmetropia, the latter being the control group. The mean age of the participants was 23.88 ± 5.87 (range, 15 to 38: 110 females
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Recurrence of macular edema in patients with branch retinal vein occlusion: a proteomic study BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-22 Yin Liu, Xiaohu Wang, Yonghong Sheng, Haili Jin, Linfeng Han, Jun Xu, Qingqing Fu, Jing Liu, Feng Ji, He Ding, Xiaochen Xu, KunChao Wu, Pengfei Zhang, Guoping Wang
Branch retinal vein occlusion (BRVO) is a common retinal vascular disease leading to severe vision loss and blindness. This study aimed to investigate and reveal the pathophysiological mechanisms underlying macular edema (ME) recurrence in patients with BRVO through a proteomic approach. We detected proteins in the aqueous humor of 14 untreated, four refractory, and four post-operative patients with
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Goldenhar syndrome with limbal neoformation, microtia and skeletal deformities: a case report and literature review BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-22 Yushan Fu, Haotian Yu, Jiajia Zhang, Nan Zhou
To report a case of a 4-year-old patient with Goldenhar syndrome. The author presents a rare case report involving a 4-year-old boy with multiple malformations. A comprehensive examination showed that the patient primarily had a limbal dermoid. He also has bilateral microtia and ear canal deformities. The skull CT scan and spine X-ray showed Maxillofacial Abnormalities and scoliosis. Whole Exome Sequencing
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Comparing forceps and self-assembled intraocular rare earth magnet in removing metallic intraocular foreign bodies in 25-guage vitrectomy BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-21 Huajin Li, Kailing Zheng, Huihang Wang, Maosong Xie
To compare the efficacy and efficiency of self-assembled intraocular rare earth magnet and forceps in removing intraocular foreign bodies(IOFBs) undergoing 25-gauge(G) pars plana vitrectomy. A total of 30 patients with metallic IOFB underwent 25-G PPV were enrolled into this study. Self-assembled intraocular rare earth magnet were used in 15 patients(bar group), and forceps were used in 15 patients(forceps
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Subjective versus objective refraction in healthy young adults BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-20 Yuval Kozlov, Michael Kinori, Sharon Armarnik, Tal Yahalomi, Aya Ekshtein, Leora Levian, Daphna Mezad-Koursh, Joseph Pikkel, Oded Ben-Ari
To evaluate objective and subjective refraction differences in healthy young adults. Data concerning candidates for the Israeli Air Force Flight Academy, as well as active air force pilots in all stages of service who underwent a routine health checkup between the years 2018 and 2019 were retrospectively analyzed. Objective refraction measured using a single autorefractometer was compared with subjective
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Efficacy of Repeated Low-Level Red Light (RLRL) therapy on myopia outcomes in children: a systematic review and meta-analysis BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-20 Mohamed Ashraf Youssef, Ahmed Ragab Shehata, Ahmed Moataz Adly, Mohamed Ragab Ahmed, Hoda Fahmy Abo-Bakr, Rehab Mahmoud Fawzy, Ahmed Taha Gouda
Myopia is the most prevalent form of refractive error that has a major negative impact on visual function and causes blurring of vision. We aimed to determine if Repeated Low-Level Red Light (RLRL) treatment is beneficial in treating childhood myopia in terms of axial length (AL), spherical equivalent refraction (SER), and sub foveal choroidal thickness (SFCT). This systematic review was performed
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Refractive outcomes of immediately sequential bilateral cataract surgery in eyes with long and short axial lengths BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-20 André S. Pollmann, Michael Trong Duc Nguyen, Milime Keyeutat, Éliane Danis, Georges M. Durr, Younes Agoumi, Samir Jabbour
To report the refractive outcomes of long (≥25.00 mm) and short (≤22.00 mm) axial length (AL) eyes undergoing immediately sequential bilateral cataract surgery (ISBCS). In this retrospective cohort study, patients who underwent ISBCS were identified and eyes of patients with bilateral long and short ALs were included. Pre- and postoperative biometry, autorefraction, and ocular comorbidities or complications
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Quantitative evaluation of ocular vascularity and correlation analysis in patients with diabetic retinopathy by SMI and OCTA BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-19 Jin Wei, Chong Chen, Yinchen Shen, Fang Li, Shu Yiyang, Haiyun Liu
To find potential relation between retrobulbar vessels and fundus microvessels and to detect sensitive and effective clinical indicators in predicting the progress of diabetic retinopathy (DR), ocular hemodynamics were measured using superb microvascular imaging (SMI) and ultrawide-field optical coherence tomography angiography (UWF-OCTA). Observational, cross-sectional study evaluating ocular hemodynamics
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Efficacy and safety of intravitreal injections of conbercept for the treatment of idiopathic choroidal neovascularization BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-19 Gaixia Zhai, Yuanzhen Su, Shaopeng Wang, Hui Lu, Na Liu
To determine the efficacy and safety of intravitreally injected conbercept, a vascular endothelial growth factor receptor fusion protein, for the treatment of idiopathic choroidal neovascularization (ICNV). This retrospective study analyzed outcomes in 40 patients (40 eyes) with ICNV who received intravitreal injections of conbercept 0.5 mg (0.05 ml) and were followed up for at least 12 months. All
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Ocular parameters associated with visual performance of enhanced monofocal intraocular lens BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-19 Da Ran Kim, Young Chae Yoon, Woong-Joo Whang, Ho Sik Hwang, Kyung-Sun Na
An enhanced monofocal intraocular lenses (IOLs) (Tecnis Eyhance ICB00 and Tecnis Eyhance Toric DIU) has been developed to enhance intermediate vision while avoiding the disadvantages of multifocal IOLs. Although many studies have demonstrated the improvement of intermediate visual acuity with enhanced monofocal IOLs, it is not known specifically for which patients these IOLs should be recommended or
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Disease quiescence in endophthalmitis patients treated with anti-VEGF injections for retinal pathologies BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-16 Brice Nguedia Vofo, Majd Saada, Antonio Rivera, Sigalit Cohen, Tareq Jaouni, Samer Khateb
The most feared complication of intravitreal injections is the development of endophthalmitis, which could lead to irreversible visual loss. The aim of this study was to characterize the clinical profiles, causative pathogens, and clinical outcome of patients post-endophthalmitis. Retrospective, single center case series study. Clinical records, causative pathogens and management of all cases of endophthalmitis
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Rotational stability of monofocal and diffractive multifocal toric intraocular lens with identical design and material: a propensity score based prospective comparative study BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-16 Runhan Shi, Dongmei Ma, Qiulin Zeng, Zhixiang Hua, Wenqian Shen, Lei Cai, Jin Yang
To compare the rotational stability of a monofocal and a diffractive multifocal toric intraocular lens(IOLs) with identical design and material. This prospective study enrolled patients who underwent plate-haptic toric IOL (AT TORBI 709 M and AT LISA 909 M) implantation. Propensity score matching (PSM) was performed to balance baseline factors. Follow-up examinations were conducted at 1 h, 1 day, 3
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Abnormalities of retinal function in type 2 diabetes mellitus patients without clinical diabetic retinopathy detected by multifocal electroretinogram BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-15 Rong-Rong Li, Yang Yang, Meng-Ge Zhang, Jie Wang, Hong Chen, Shan Liu, Hui Miao, Yun-Chang Wang
To study the changes of retinal function in type 2 diabetes mellitus(DM) patients without apparently diabetic retinopathy via multifocal electroretinogram. Methods: Thirty-six type 2 DM patients (72 eyes) without visible diabetic retinopathy were selected as the experimental group, and thirty-five healthy subjects (70 eyes) were selected as the control group. All subjects were underwent multifocal
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Influencing factors comparing different vault groups after phakic implantable collamer lens implantation: review and meta-analysis BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-15 Pengcheng Zhang, Chenjun Guo, Song Wang, Wenshan Jiang, Dan Wang, Hong Yan
Studies on the factors affecting vault after posterior chamber phakic Implantable Collamer Lens (ICL) have been carried out, but most of them are single-centered and subjective selections of parameters. The present study aimed to systematically analyze the factors for vault. A systematic review of case series, case-control, and cohort studies derived from the articles published in PubMed, the Cochrane
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Knowledge about glaucoma among adults in Africa: a systematic review BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-14 Wondwossen Yimam, Tamrat Anbesaw, Muhammed Seid, Prem Kumar, Hawa Wolie
Africa is one of the continents with a substantial burden of glaucoma, where it is approximately twice as common as it is worldwide. If left untreated, glaucoma can cause blindness and permanent vision loss if it is not addressed promptly. Good knowledge is essential for preventing glaucoma’s irreversible blindness and ocular damage. However, no systematic review has been done to report the pooled
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Tuberculum meningioma with recovery of glaucoma-like visual field defects after chiasmal decompression: a case report BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-14 Kaori Hanai, Masato Hashimoto, Hirohiko Nakamura
To report a case of tuberculum meningioma with recovery of glaucoma-like visual field defects after chiasmal decompression. A 39-year-old woman presenting with headache was found to have bilateral arcuate retinal nerve fiber layer (RNFL) thinning on optical coherence tomography (OCT) with a corresponding arcuate scotomas consistent with glaucomatous change. However a suprasellar tumor compressing the
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The distribution characteristics of strabismus surgery types in a tertiary hospital in the Central Plains region during the COVID-19 epidemic BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-14 Lijuan Lang, Kexin Guo, Luxi Zhang, Jiong Zhang, Yujie Liu, Junbo Rong, Limin Xu, Zhigang Li
This study aimed to analyze the distribution of different types of strabismus surgery in a tertiary hospital in Central China during the three-year period of the COVID-19 pandemic. A retrospective analysis was conducted on the clinical data of strabismus patients who underwent surgery and were admitted to the Department of Strabismus and Pediatric Ophthalmology at the First Affiliated Hospital of Zhengzhou
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A case of iridoschisis with partial lens dislocation in both eyes BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-14 Tong-Tong Niu, Wen-Jian Xin
Iridoschisis is a rare condition that primarily affects individuals aged 60–70 years. The predominant characteristics of iridoschisis involve the tissue splitting and separation of the iris stromal layers, often resulting in two distinct layers and the presence of floating fibers in the anterior chamber. This article reports the case of a 48-year-old male with iridoschisis with partial lens dislocation
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Peripheral and posterior pole retinal changes in highly myopic Chinese children and adolescents BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-13 Wenli Zhang, Fan Yang, Shirong Chen, Tingkun Shi
This study was conducted to evaluate the prevalence and related factors of peripheral and posterior pole retinal changes in highly myopic Chinese children and adolescents. A hospital-based cross-sectional study was designed. A total of 120 subjects with high myopia were recruited and underwent cycloplegic refraction, dilated fundus examination, and optical coherence tomography. A statistical analysis
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Correlation between choroidal vascularity and retrobulbar ocular blood flow changes and thyroid-associated ophthalmopathy activity: a cross-sectional study BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-13 Xinghong Sun, Mengru Su, Xiaowen Zhang, Haiyun Shen, Zhenggao Xie, Wentao Kong, Dandan Zhu
To evaluate the alterations in retrobulbar color Doppler imaging (CDI) parameters and retinal/choroidal optical coherence tomography angiography (OCTA) parameters and their association with the clinical activity and severity in thyroid-associated orbitopathy (TAO) patients. In this study, the retrobulbar flow parameters including resistance index (RI), Pulsatile Index(PI), peak systolic velocity (PSV)
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Macular hole following scleral buckling for rhegmatogenous retinal detachment: a case series BMC Ophthalmol. (IF 2.0) Pub Date : 2024-02-13 Fangyu Wang, Zhongqiao Zhu, Hong Yan, Yao Yang, Laxiao Niu, Jing Liu
Macular hole (MH) development following scleral buckling (SB) surgery for rhegmatogenous retinal detachment (RRD) repair is rare. This study presents both full-thickness MH (FTMH) and lamellar MH (LMH) cases following SB for the treatment of RRD. Clinical records of patients undergoing SB surgery for treatment of RRD at the Xi’an People’s Hospital (Xi’an Fourth Hospital) from January 2016 to December