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Non-Pathogenic Aspergillus oryzae Acute Exogenous Endophthalmitis after Penetrating Keratoplasty: The First Case Report in the Literature. Case Rep. Ophthalmol. Pub Date : 2023-11-27 Luigi Mosca,Laura Guccione,Maria Emanuela Toro,Luca Scartozzi,Romina Fasciani,Riccardo Torelli,Maurizio Sanguinetti,Stanislao Rizzo
The authors report a singular case of post-operative exogenous fungal endophthalmitis caused by a non-pathogenic fungal agent: Aspergillus oryzae. A 75-year-old Caucasian woman with post-penetrating keratoplasty fungal endophthalmitis due to a nonpathogenic A. oryzae, resistant to the current azoles anti-fungal agents, was treated with subtotal vitrectomy, intravitreal injection, and systemic voriconazole
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Familial Exudative Vitreoretinopathy Initially Diagnosed as Incontinentia Pigmenti in an Asymptomatic Teenager: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-11-24 Reem Karmouta,Irena Tsui,Monica Khitri
In this case report, we aim to illustrate a presentation of familial exudative vitreoretinopathy (FEVR) that closely resembles incontinentia pigmenti (IP) and the role of genetic testing that is of no cost to the patient in providing the correct diagnosis. We present a case of an 11-year-old female-to-male transgender patient with a history of hypodontia and skin hypopigmentation who was incidentally
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Long-Term Structural and Functional Assessment of Doyne Honeycomb Retinal Dystrophy following Nanosecond 2RT Laser Treatment: A Case Series. Case Rep. Ophthalmol. Pub Date : 2023-11-23 Andrea Cusumano,Benedetto Falsini,Michele D'Ambrosio,Fabian D'Apolito,Jacopo Sebastiani,Jung Hee Levialdi Ghiron,Emiliano Giardina,Raffaella Cascella
Introduction Doyne honeycomb retinal dystrophy (DHRD), or autosomal dominant radial drusen, is a genetic disease caused by pathogenic variants of the epidermal growth factor (EGF)-containing fibulin-like extracellular matrix protein 1 EFEMP1 gene and is characterized by the formation of subretinal drusenoid deposits. In a previous study, we reported the short-term beneficial effects of nanosecond laser
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Marked Choroidal Thinning Observed after Intravitreal Brolucizumab Injection. Case Rep. Ophthalmol. Pub Date : 2023-11-14 Yoshiki Ueta,Ryoma Kamada,Yuji Watanabe,Nobuya Tanaka
Introduction Here, we report a case of severe intraocular inflammation (IOI) and prominent choroidal thinning following the initial intravitreal brolucizumab injection (IVBr). Case Presentation The patient was a 75-year-old Japanese man with type 2 age-related macular degeneration of both eyes. Until 2015, he had undergone two intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections
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Two Pediatric Patients with Acute Acquired Comitant Esotropia as the First Symptom of Brainstem Tumor: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-11-08 Ayaka Yagasaki,Taishi Miyase,Shota Sakai,Kiyofumi Mochizuki,Hirokazu Sakaguchi,Teiji Yagasaki,Naoyuki Ohe,Shiho Yasue,Saori Endo,Michio Ozeki
Introduction Acute acquired comitant esotropia (AACE) is an acquired strabismus with uncrossed sudden-onset diplopia due to esodeviation, comitant esotropia without accommodation factor, or paretic eye movement. The diagnosis of AACE entails differentiation from incomitant esotropia caused by abnormalities in the central nervous system. We present 2 pediatric patients with AACE as the first symptom
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A Case of Dellen Formation following 27-Gauge Vitrectomy with Rapid Improvement by Scleral and Conjunctival Sutures. Case Rep. Ophthalmol. Pub Date : 2023-11-06 Saori Yamaguchi,Yuji Yoshikawa,Minami Chino,Kei Shinoda
Introduction Dellen is a corneal disease characterized by shallow, saucer-like excavations at the corneal margin. Herein, we presented a case of dellen formation that developed following a 27-gauge pars plana vitrectomy (PPV) and was rapidly resolved using scleral and conjunctival sutures. Case Presentation A 73-year-old woman underwent a 27-gauge PPV for the epiretinal membrane of the right eye. Intraoperatively
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Refractive Management of Surgical-Induced Presbyopia in a Young Patient with Vision-Related Quality of Life Complaints: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-11-06 Catarina Castro,Paulo Sousa,Ana Carolina Abreu,Sílvia Monteiro,Maria do Céu Pinto
Visual difficulties can negatively impact life quality. Our purpose was to report the refractive surgical planning and outcomes of a young patient with mixed astigmatism and phacoemulsification-induced presbyopia due to congenital cataracts who was unsatisfied with her vision-related quality of life. A 32-year-old woman, submitted to phacoemulsification with implantation of a monofocal intraocular
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A Case of Traumatic Submacular Hemorrhage Treated with tPA and Pneumatic Displacement. Case Rep. Ophthalmol. Pub Date : 2023-11-01 Lorenzo Motta,Matteo Ripa,Korina Theodoraki,Timothy L Jackson,Dominic McHugh
This is a case of a 31-year-old female who presented to the emergency department at a London teaching hospital with a 24-h history of visual loss following an assault. The ophthalmological routine examination showed a submacular hemorrhage (SMH), and a computerized tomography scan demonstrated a displaced orbital floor fracture with inferior rectus entrapment and a medial wall fracture. To induce displacement
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Paracentral Acute Middle Maculopathy in Migraines with Aura. Case Rep. Ophthalmol. Pub Date : 2023-10-31 Daniel Milad,Fares Antaki,Andrew Farah,Karim Hammamji,Marc Saab
Paracentral acute middle maculopathy (PAMM) has recently been described following episodes of migraine. In this report, we present a case of PAMM and describe the role of en face optical coherence tomography (OCT). A 75-year-old woman presented with subjective vision loss over a 2-week period in the right eye. She was known for migraines with aura that presented with progressive spreading of positive
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Two-Step Iridocorneal Endothelial Syndrome Management: Endocapsular Intraocular Lens and Artificial Iris Followed by Descemet's Stripping Automated Endothelial Keratoplasty. Case Rep. Ophthalmol. Pub Date : 2023-10-27 João Pinheiro-Costa,Inês Coelho-Costa,Fernando Falcão-Reis,Tiago Monteiro,Manuel Falcão
A 54-year-old female presented with complaints of glare and progressive visual loss OS with a corrected distance visual acuity (CDVA) OS of 20/100. The patient had grade 1 corneal edema with a "beaten bronze" appearance on specularly reflected light, pseudopolycoria, and a nuclear sclerotic cataract. The diagnosis of nuclear cataract and progressive iris atrophy iridocorneal endothelial (ICE) syndrome
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Autologous Retinal Transplant Repeat Surgery after Initial Graft Failure: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-10-20 TsunKang Chiang,Jeffrey Chu,Ankur Mehra,Warren Sobol
Autologous retinal transplant (ART) has become an increasingly explored surgical option for managing large chronic holes refractory to standard surgical treatments. However, management strategies for patients who already failed a previous ART are less well-understood. Here, we report on a case of a successful repeat retinal transplant for a refractory macular hole after a previously dislocated ART
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Use of Amniotic Membrane Transplant and Deep Anterior Keratoplasty in a Patient with Bilateral Acanthamoeba Infectious Keratitis: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-10-20 Carlos A Müller-Morales,Guillermo Raul Vera-Duarte,Valeria Oliva-Bienzobas,Arturo Ramirez-Miranda,Alejandro Navas,Enrique O Graue-Hernandez
The aim of this study was to report a case with the use of amniotic membrane transplant and deep anterior keratoplasty in a patient with bilateral Acanthamoeba infectious keratitis as a treatment. A 20-year-old male presented with bilateral Acanthamoeba keratitis (AK) who was initially diagnosed with herpetic keratitis receiving full antiviral and corticosteroid topical treatment without any improvement
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Sealed Unilateral Full-Thickness Macular Hole with Amniotic Membrane Graft in a Patient with Alport Syndrome: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-10-18 Sayena Jabbehdari,Pedro S Tetelbom,David Warner,Sami H Uwaydat
We present a case of unilateral full-thickness macular hole (MH) successfully repaired with an amniotic membrane (AM) graft in a patient with Alport syndrome. A 58-year-old Asian female with past medical history of Alport syndrome diagnosed at early stage, presented with a 5-week history of vision loss in her right eye. Examination of her eyes showed normal retinal vessels and an MH measuring 1,300
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Blepharokeratoconjunctivitis Presumably Caused by Paederus fuscipes, a Beetle: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-10-16 Takashi Ono,Ryohei Nejima,Katsuhito Kinoshita,Yosai Mori,Shinichiro Ohtani,Takashi Miyai,Takuya Iwasaki,Kazunori Miyata
Toxicity of Paederus species to eyes has scarcely been reported. This report presents a case of chemical blepharokeratoconjunctivitis with delayed re-epithelialization caused by Paederus fuscipes in a patient with dry eye after laser-assisted in situ keratomileusis (LASIK). A 47-year-old woman who had undergone LASIK for myopia 10 years prior experienced visual disturbance and pain in her left eye
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Novel Surgical Treatment of an Intraretinal Juxtapapillary Hemangioblastoma Using Intraocular Diathermy Forceps: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-10-16 Koen A van Overdam,Anass Hajjaj,Lisette M Smid,Emine Kiliç,Jan H de Jong
The surgical treatment of intraretinal juxtapapillary retinal hemangioblastomas (JRHs) was previously contraindicated because of the significant risk of collateral damage to the macula and optic nerve. This case report discusses the effectiveness and safety of a novel surgical technique using intraocular bipolar diathermy forceps to coagulate feeder and draining blood vessels of an intraretinal JRH
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Supplementary Implantation of 1stQ AddOn® Sulcus-Fixated Intraocular Lens to Treat Negative Dysphotopsia: A Retrospective Case Series. Case Rep. Ophthalmol. Pub Date : 2023-10-13 Maxim Van Slycken,Guy Sallet,Thierry Derveaux
Negative dysphotopsia (ND) refers to the subjective perception of an arc-shaped darkness or shadow in the temporal field of vision. This condition occurs after uneventful cataract surgery with an in-the-bag intraocular lens (IOL). To address this issue, supplementary implantation of conventional three-piece IOLs in the sulcus or dedicated supplementary Rayner Sulcoflex® IOL have been used successfully
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Bilateral Optic Disc Swelling with Persistent Visual Loss in Anemia: Case Report. Case Rep. Ophthalmol. Pub Date : 2023-10-11 Kim Van Langenhove,Marcel Paulus Maria Ten Tusscher
A 56-year-old man with a medical history of alcoholic cirrhosis presented with acute bilateral loss of vision. On admission, the patient had pale skin and low arterial pressure. Ophthalmic examination demonstrated a visual acuity of 6/9 in the right eye and the absence of light perception in the left. Automated perimetry revealed a superior altitudinal defect in the right eye. Optic disc swelling,
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Management of Large Conjunctival Cysts in a Patient with Stevens-Johnson Syndrome: A Case Report and Review of the Literature. Case Rep. Ophthalmol. Pub Date : 2023-10-06 Sadid Hooshmandi,Kiana Hassanpour,Amirreza Veisi,Vahid Movafaghi,Farideh Langari,Mohammad-Mehdi Sadoughi,Mohammad Ali Javadi
Stevens-Johnson syndrome (SJS) is a life-threatening mucocutaneous disease with various etiologies including drugs, infections, and malignancies. Ocular manifestations of SJS vary from the membrane, symblepharon formation, and epithelial defect in the acute phase to trichiasis, eyelid margin keratinization, and lacrimal duct obstruction in the chronic phase. A 13-year-old boy with a history of drug-induced
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Cohen Syndrome: Novel VPS13B Genetic Variants in a Male Portuguese Patient with Pigmentary Retinopathy. Case Rep. Ophthalmol. Pub Date : 2023-10-06 Rodrigo Vilares-Morgado,Ana Margarida Ferreira,Renato Santos-Silva,Rita Quental,Ângela Carneiro,Sérgio Estrela-Silva
The purpose of this clinical report was to describe a case of Cohen syndrome with its classical ophthalmological manifestations and novel VPS13B genetic variants. A 39-year-old Caucasian male patient with severe rod-cone retinal dystrophy and no history of parental consanguinity was referred to our ophthalmology department. Ophthalmologic history included high bilateral myopia and a 3-year prior bilateral
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Severe Corneal Melt Post Trans-Scleral Cyclodiode in a Case of Neovascular Glaucoma Secondary to Coats Disease: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-10-06 Jackson Chee Chea Lee,Geoffrey Zhi Peng Chan,Humma Shahid
A novel case of neurotrophic keratitis and severe corneal melt requiring surgical management is presented 1 month following trans-scleral cyclodiode for Coats disease and neovascular glaucoma. Risk factors contributing to the complication include previous extracapsular cataract surgery, perioperative use of topical non-steroidal anti-inflammatories and dexamethasone/neomycin, as well as other topical
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A Case of Nocardia africana-Related Keratitis. Case Rep. Ophthalmol. Pub Date : 2023-10-06 Winai Chaidaroon,Prangchanok Sawetwong,Sirinya Manochomphu
Nocardia spp. are gram positive, aerobic, weakly acid-fast bacteria. Nocardia spp. keratitis is a rare ocular infection classically described following corneal injury or vegetative and soil exposure. However, keratitis caused by Nocardia africana had never been reported in the literature. We first reported a 70-year-old male who had a traumatic ocular injury to his left eye a month ago. With his complaint
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Berlin's Edema with Atypical Optical Coherence Tomography Findings: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-10-02 Homayoun Nikkhah,Narges Karrabi,Farangis Yazdanjou
Berlin's edema is an acute traumatic maculopathy following ocular blunt trauma, with the major site of injury is photoreceptor outer segments and retinal pigment epithelium (RPE). Optical coherence tomography (OCT) is a useful tool to diagnose and follow microstructural changes in Berlin's edema. In this report, we present an atypical case of Berlin's edema that resembled Vogt-Koyanagi-Harada disease
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Sterile Corneal Infiltrates following Cataract Surgery: Case Series. Case Rep. Ophthalmol. Pub Date : 2023-09-26 Antonella Franch,Silvia Bini,Lorena Francescutti,Federica Birattari,Pia Leon,Daniele Bonamartini,Tommaso Gambato,Romeo Altafini
We report a case series of 26 eyes of 26 patients undergoing planned cataract surgery from December 2021 to March 2022, who were diagnosed as having whitish round infiltrates in the surgical corneal incisions. The infiltrates were detected at the first check after 5-8 days from cataract surgery and were located either within the main corneal incision and/or in the smaller incisions. Corneal infiltrates
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PHACE(S) Syndrome with Ocular Involvements and No Periocular Hemangioma. Case Rep. Ophthalmol. Pub Date : 2023-09-22 Aisha Sheriff Kalambe,Kazunobu Sugihara,Kei Yamamoto,Sakiko Kawano,Chigusa Oyama,Takeshi Taketani,Kenji Hayashida,Masaki Tanito
PHACE(S) syndrome is a neurocutaneous disorder with a hallmark finding of an infantile facial hemangioma (IFH) >5 cm. Eye examination of patients with PHACE(S) syndrome with no IFH at periorbital region is reported to be of low yield. We report a unique case of the syndrome with ocular manifestations without periorbital IFH or systemic findings. A 3-week-old female infant with right periauricular IFH
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Documented Reperfusion of the Retina on Fluorescein Angiography after Administration of Intravenous Prostaglandin E1 for Central Retinal Artery Occlusion: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-09-21 J Anthony Chacko,Heather V Broyles,Joseph G Chacko,Sami H Uwaydat
Central retinal artery occlusion (CRAO) can result in devastating permanent vision loss. Presently, there is no evidence-based treatment for CRAO that is widely accepted. In the literature, multiple studies propose intravenous (IV) prostaglandin E1 (IV PGE1) as a potential treatment option for patients with CRAO. We illustrate 2 cases of CRAO successfully treated with IV PGE1. In both cases, our patients
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Macula-Off Retinal Detachment with Refractory Macular Hole Previously Closed with Autologous Platelet-Rich Plasma: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-09-19 Guglielmo Parisi,Federico Ricardi,Giacomo Boscia,Andrea Ghilardi,Francesco Gelormini,Paola Marolo,Matteo Fallico,Sergio D'Antico,Marika Salafia,Michele Reibaldi
The purpose of this report was to present a case of a refractory full-thickness macular hole (FTMH) complicated with recurrent retinal detachment (RD) previously treated with an autologous platelet-rich plasma (aPRP) plug. A 65-year-old male patient presented to our department with a FTMH, RD, and a giant retinal break. Preoperative best corrected visual acuity (BCVA) was 1.40 logMAR (20/500). A 25-G
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Long-Term Follow-Up of a Family with Retinal Dystrophy Caused by RPE65 Mutation. Case Rep. Ophthalmol. Pub Date : 2023-09-19 Ágnes Jánossy,Eszter Vizvári,Máté Lőrincz,Szilvia Pál,Dóra Nagy,György Benedek,Edit Tóth-Molnár,Márta Janáky
We present here the case histories of two siblings, a boy and a girl, with Leber's congenital amaurosis (LCA). The diagnosis was based on non-recordable full-field electroretinogram (ffERG). The long-term ophthalmologic follow-up included kinetic perimetry (Goldmann), visual evoked potentials with flash stimulation, optical coherence tomography (OCT: B-scan images at the area of fovea), and multifocal
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Rare Case of Bilateral Orbital Cellulitis in an Adult, Caused by Enterococcus faecalis. Case Rep. Ophthalmol. Pub Date : 2023-09-18 Georgi Balchev,Vesela Ivancheva,Zehra Bahar Gey
Orbital cellulitis is a serious, life-threatening infection, typically in paediatric patients, and its bilateral presentation in adults is atypic. We present an unusual bilateral manifestation of orbital cellulitis and abscess, caused by Enterococci in an adult patient. E. faecalis is an extremely rare cause of orbital inflammation and we found three published case reports only, all of which are unilateral
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Semi-Autologous Corneal Transplantation with Simultaneous Bilateral Surgery: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-09-12 Nefeli E Kounatidou,Dimitra Kopsini,Allister Gibbons,Ashley M Crane,Sotiria Palioura,Eduardo C Alfonso
The present report describes a case of semi-autologous corneal transplantation with bilateral surgery using two operating microscopes simultaneously. An 86-year-old man with history of six prior failed penetrating keratoplasties in his right eye presented with decreased vision. His other eye was deeply amblyopic but had a clear 30-year-old Castroviejo-square graft with an endothelial cell count of
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Eccentric Fixation and Good Visual Acuity in a Child with Large Traumatic Macular Hole: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-09-12 Hassan Asadigandomani,Nader Mohammadi,Hamid Riazi-Esfahani,Motahhareh Sadeghi,Elias Khalili Pour
A girl of 8 years old was referred to our clinic with a history of penetrating injury to her left eye 6 years ago with light perception vision and a large traumatic macular hole in her right eye. Her right eye's vision was 4/10 when she first visited our clinic. Considering the patient's one-eye status, her parents' reluctance to undergo surgery, and the possibility of spontaneous closure of traumatic
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A Case of Binocular Metastatic Choroidal Tumor Originating from Pulmonary Adenocarcinoma Successfully Treated with Molecular Target Therapy. Case Rep. Ophthalmol. Pub Date : 2023-09-08 Masataka Yamaoka,Tsutomu Igarashi,Naka Shiratori,Keiki Miyadera,Teppei Sugano,Rintaro Noro,Hiroshi Takahashi
The occurrence of ocular metastasis from lung cancer is uncommon. In our current case, we report on a 64-year-old male patient found to have metastatic lesions in both choroids after being diagnosed with lung adenocarcinoma. As the patient was found to have a mutation in the epidermal growth factor receptor (EGFR), he was treated with the EGFR tyrosine kinase inhibitor (EGFR TKI), afatinib. However
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Presumed Melanocytoma-Associated Choroidal Neovascular Membrane with Hemorrhage Successfully Treated with Intravitreal Aflibercept Injections. Case Rep. Ophthalmol. Pub Date : 2023-09-06 Austin S Yu,Jordan A Sugarman,Stephanie J Weiss
A patient presented with melanocytoma and associated choroidal neovascular membrane with hemorrhage involving the macula. The patient was treated with monthly aflibercept (Eylea) injections with significant improvement of best corrected visual acuity. In this report, we explore the development of a choroidal neovascular membrane (CNVM) formation in a patient with melanocytoma and the effect of intravitreal
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Pathogenicity of Variant m.13528A>G in MT-ND5 in Leber's Hereditary Optic Neuropathy Is Unsupported. Case Rep. Ophthalmol. Pub Date : 2023-09-05 Josef Finsterer,Sounira Mehri
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Reticular Pseudodrusen Voids after Rhegmatogenous Retinal Detachment. Case Rep. Ophthalmol. Pub Date : 2023-08-30 Vegard Asgeir Forsaa,Vilde Marie Thomseth
We present a case of reticular pseudodrusen (RPD) regression on multimodal retinal imaging following a rhegmatogenous retinal detachment. Two mechanisms of action can be postulated. The subretinal deposits dissolve due to voluminous subretinal fluid during retinal separation from the retinal pigment epithelium and are in turn mechanically cleared during retinal re-attachment surgery. Alternatively
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Atypical Central Retinal Artery Occlusion following COVID-19 Infection: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-08-30 Hamid Reza Heidarzadeh,Mojtaba Abrishami,Mehrdad Motamed Shariati,Seyed Hossein Ghavami Shahri,Mohammad Reza Ansari Astaneh
Herein, we report a patient with atypical central retinal artery occlusion (CRAO) following COVID-19 recovery. A 44-year-old male was referred to the emergency room with a history of diplopia and sudden-onset painless visual loss in his left eye. He had a history of 1-week hospitalization for severe COVID-19 infection with pneumonia 3 weeks before, with positive real-time reverse transcription polymerase
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Isolated Kaposi's Sarcoma of the Bulbar Conjunctiva as an Initial Manifestation of AIDS: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-08-30 Hend Alsawadi,Abdulaziz Al-Somali,Hatim Najmi,Fatimah Al-Mubarak
Kaposi's sarcoma (KS) is a malignant vascular endothelium-cell-derived tumor caused by human herpesvirus 8. It is one of the most common tumors among human immunodeficiency virus (HIV)-infected patients; however, isolated KS is rarely reported as the initial presentation. This study describes a rare case in which isolated KS of the bulbar conjunctiva was the first presenting symptom leading to the
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Optic Neuritis following Second Administration of COVID-19 Vaccine: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-08-23 Edward Saxton,Binita Panchasara,Susan Sarangapani
A 28-year-old woman presented to eye casualty with signs and symptoms suggestive of optic neuritis following a recent COVID-19 vaccination (the Moderna mRNA-1273 vaccine). The best corrected visual acuity was 6/15 in the right eye and 6/6 in the left eye with a relative afferent pupillary defect in the right eye. Following examination and investigation, she was found to fit the McDonald criteria for
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Subperiosteal Orbital Hematoma: A Rare Clinical Manifestation of Sickle Cell Disease - A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-08-18 Najib-Georges Hanna,Asma Musleh,Hasan Khan,Emaan Chaudry,Corinne Lahoud
Sickle cell disease (SCD), an inherited vaso-occlusive disorder, results in recurrent painful episodes and a variety of serious systemic complications that can lead to severe disabilities and even death. Here, we report a case of a 19-year-old African American patient with homozygous sickle cell trait who presented with right upper lid edema and ptosis, 3 days after his admission to the hospital following
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Three-Year Follow-Up of Results of Intraocular Lens Fixation in Patients with Retinitis Pigmentosa. Case Rep. Ophthalmol. Pub Date : 2023-08-16 Gen Miura,Takayuki Baba
This is a retrospective, consecutive, noncomparative case series of 6 eyes of 5 retinitis pigmentosa (RP) patients who had undergone pars plana vitrectomy (PPV) and intraocular lens (IOL) implantation. The aim of this case series was to report the long-term outcomes of PPV with IOL implantation in patients with RP). The surgical procedures, visual function, refractive error, corneal endothelial cell
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Delayed Bacterial Endotheliitis and Endophthalmitis 11 Years after Cataract Surgery. Case Rep. Ophthalmol. Pub Date : 2023-08-16 Elisabeth Poon,Alexander Poon,Penelope McKelvie,Lewis Levitz,Ehud Zamir
Infective endophthalmitis is an uncommon complication following intraocular surgery. Chronic endophthalmitis may present some time after intraocular surgery, making the diagnosis challenging. Cutibacterium acnes is a well-recognised causative agent of these chronic infections. Practitioners should be aware of the conditions required to culture this slow-growing organism. We report a case of delayed
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Monitoring Delayed Toxoplasmosis-Related Branch Retinal Artery Occlusion Using Widefield en face Optical Coherence Tomography and Multimodal Imaging. Case Rep. Ophthalmol. Pub Date : 2023-08-16 Prashanth Iyer,Noy Ashkenazy,Jeremy Liu,Diana Laura,Marilyn Ann Marquez,Thomas Albini
Ocular toxoplasmosis has a known, rare association with acute retinal artery occlusion (RAO). We describe a 21-year-old male who presented with acute focal toxoplasmosis chorioretinitis in the right eye treated with intravitreal clindamycin, intravitreal dexamethasone, and adjunct oral therapy for vision-threatening retinitis with subsequent quiescence. Nine months from his initial presentation, the
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Eyelid Soft Tissue Chondroma: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-08-14 Abeer A AlHazzani,Rawan H Malaikah,Faisal A Altahan,Maria A Arafah,Yasser H Al-Faky
Soft tissue chondromas are rare benign tumors that occur in extraosseous and extra-synovial locations. We report herein a rare presentation of eyelid soft tissue chondroma in a 45-year-old male presented with a 2-year history of a slowly enlarging subcutaneous firm mass on the left upper eyelid, and complete excision of the lesion followed by histopathological examination rendered the diagnosis of
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A Rare Case of Direct Spontaneous Carotid-Cavernous Fistula in a 6-Month-Old Infant and Review of the Literature. Case Rep. Ophthalmol. Pub Date : 2023-08-14 Sandeep Pal,Pradhnya A Sen,Narendra Patidar,Harshdeep Singh Gabba,Sangeeta Bhadra
Direct or type A CCFs are the direct connection between the cavernous segment of the internal carotid artery and the cavernous sinus. While most direct CCFs are caused by trauma, spontaneous direct CCFs are extremely rare in infants. In this report, we describe a 6-month-old child with bulges in the right eye that had been present since 20 days after birth. On examination, there was a right eye abduction
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Intermittent Orbital Pain due to Hemodynamic Collapse of an Orbital Varix: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-08-14 Naoki Kaneko,Daniel B Rootman,Ariel Takayanagi,Robert Goldberg,Gary R Duckwiler,Satoshi Tateshima
Orbital varices typically present with symptoms related to dilation or thrombosis. We describe a rare presentation of an orbital varix with pain caused by hemodynamic collapse of the varix. A woman in the third decade presented with position-dependent orbital pain and enophthalmos. She was found to have an intraorbital varix and a separate pterygoid varix. The patient underwent endovascular treatment
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Hypertensive Retinopathy as a Presenting Sign of Pheochromocytoma with Malignant Hypertension: A Child Case. Case Rep. Ophthalmol. Pub Date : 2023-08-11 Filippo Billia,Nadia Palmieri,Andrea Maccari,Feliciana Menna,Andrea Consigli
A 13-year-old was admitted to our clinic complaining about a vision loss of over 2 weeks. Bilateral optic disc edema, peripapillary flame-shaped hemorrhages, macular star pattern exudates, and cotton wool spots were found in fundoscopic examination. The OCT exam showed bilaterally serous retinal detachments in sub-foveal region with intraretinal exudates. A pediatric examination found a high systemic
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Massive Uveal Relapse of Retinoblastoma Presumed to Be Choroidal Tumorous Involvement: Case Series. Case Rep. Ophthalmol. Pub Date : 2023-08-10 Fariba Ghassemi,Masoud Rahimi,Hamid Riazi-Esfahani,Alireza Khodabandeh,Babak Masoomian,Sara Taghizadeh,Shervin Sharifkashani
We report the choroidal and ciliary body invasion by retinoblastoma (RB) in a salvaged eye after complete and successful primary treatment. Case 1: A 25-month-old boy was referred due to group B RB lesions based on the International Classification of RB (ICRB; groups A-E) in the right eye (OD). His left eye (OS) was enucleated because of advanced group E RB. After 47 months of uneventful follow-up
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Effect of the First-Line Therapy with Osimertinib for a Metastatic Choroidal Tumor in Advanced-Stage Lung Cancer: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-07-13 Ikuko Umeda,Yuta Kitamura,Hirotaka Yokouchi,Takayuki Baba
Although the advent of molecular-targeted drugs has improved the prognosis of various cancers, the long-term prognosis and side effects as the first-line therapy for metastatic choroidal tumors remain unclear. We describe a case in which the first-line therapy of osimertinib has shown long-term successful and minimum side effect responses for metastatic choroidal tumors in a patient with advanced-stage
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Lymphocytic Panhypophysitis Mimicking Glaucoma: Case Report. Case Rep. Ophthalmol. Pub Date : 2023-07-12 Phillip Howard Keys,Patrick J Hunt,Clement Anozie,Samir Cayenne,Pamela Davila-Siliezar,Noor Laylani,Andrew G Lee
Lymphocytic hypophysitis (LH) is a primary inflammatory disorder of the pituitary gland and infundibulum that commonly manifests in both mass effect and endocrinologic symptoms. Although the exact pathophysiology remains unclear, it has been increasingly linked to an autoimmune process. Complications arise by two separate mechanisms. Inflammation in the sella can lead to headaches and visual field
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Preservation of Vision after Early Recognition of Anterior Ischemic Optic Neuropathy in a Patient with Sepsis. Case Rep. Ophthalmol. Pub Date : 2023-07-12 Amir R Vosoughi,Jonathan A Micieli
Non-arteritic ischemic optic neuropathy (NAION) can rarely occur in the setting of sudden vascular compromise, especially in patients with a "disk-at-risk" appearance. Anemia and hypotension are believed to be the main precipitators of shock-induced NAION. Early recognition of this phenomenon can prevent further visual loss and result in partial visual recovery. We here present a 56-year-old patient
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Optic Nerve Sheath Fenestration as Adjuvant Treatment for Severe Pseudotumor Cerebri Syndrome Induced by All-Trans Retinoic Acid. Case Rep. Ophthalmol. Pub Date : 2023-07-12 Kenzo Hokazono,Leonardo Provetti Cunha,Rony Carlos Preti,Leandro Cabral Zacharias,Mário Luiz Ribeiro Monteiro
All-trans retinoic acid (ATRA) is a vitamin A derivative which can increase intracranial pressure, causing visual loss and papilledema. Those patients should be treated similarly to others patients with idiopathic intracranial hypertension. We described a case of a 32-year-old woman presenting with severe visual loss and intracranial hypertension induced by ATRA for acute promyelocytic leukemia, which
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Undesirable High Astigmatism after Penetrating Keratoplasty in Pseudophakia Corrected with an Add-On Toric Intraocular Lens. Case Rep. Ophthalmol. Pub Date : 2023-07-10 Pau Cid-Bertomeu,Magí Vilaltella,Valentín Huerva
The purpose of the present case is to report the visual outcomes of a pseudophakic patient with high post-penetrating keratoplasty astigmatism treated with implantation of toric AddOn® intraocular lens (IOL) in the sulcus. A 79-year-old man with a ophthalmologic history of pseudoexfoliative glaucoma and Fuchs endothelial dystrophy had a graft failure after Descemet's stripping automated endothelial
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Orbital Gas after 25-Gauge Pars Plana Vitrectomy with Incorrect Gas Mixture. Case Rep. Ophthalmol. Pub Date : 2023-07-10 Noy Ashkenazy,Carl J Danzig,Andrew J Rong,Sarah P Read,Michelle M Maeng,Harry W Flynn,Thomas A Albini
We present 2 cases of sutureless 25-gauge pars plana vitrectomy and fluid-gas exchange, in which incorrect gas concentrations likely led to elevated intraocular pressures and retrobulbar gas. Combined removal of orbital gas with anterior orbitotomy and pars plana vitrectomy was performed in the first case to address expanding intraocular and retrobulbar gas resulting from a suspected error in gas dilution
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A Case of Bilateral Frosted Branch Angiitis after mRNA COVID-19 Vaccination. Case Rep. Ophthalmol. Pub Date : 2023-07-10 Mai Kitaoka,Takako Ohnishi,Satoshi Sugaya,Harumasa Yokota,Taiji Nagaoka,Satoru Yamagami
We report a case of bilateral frosted branch angiitis (FBA) following mRNA-1273 COVID-19 vaccination. A 79-year-old male was referred to our hospital with a sudden onset of blurred vision in the right eye, which occurred during his return home after receiving the third dose of a messenger RNA (mRNA) COVID-19 vaccine. Fundoscopy revealed severe retinal vasculitis with sheathing of the artery and vein
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Infestation of the Eyelid by an Egg-Laying Tick: Case Report. Case Rep. Ophthalmol. Pub Date : 2023-07-07 Sina Hakami,Youssef Afifi,Younes Azzagnuni,Dorine Makhoul,Aurélie Le
In this report, we describe a rare case of a tick egg-laying infestation of the eyelid. A 7-year-old girl consulted our hospital after a trip in Thailand for an itchy and painful eyelid. The first examination at the slit lamp showed the tick's body attached to the left superior eyelid margin, surrounded by its eggs. The tick detached itself afterward and a tobramycin prophylactic treatment was introduced
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A Case of Autism Spectrum Disorder with Perforated Keratomalacia due to Vitamin A Deficiency. Case Rep. Ophthalmol. Pub Date : 2023-07-07 Daisuke Nakata,Sayaka Kakehi,Hiroshi Okada,Koji Hirano,Masayuki Horiguchi,Yasuki Ito
We report a case of a patient with autism spectrum disorder (ASD) and perforated keratomalacia secondary to vitamin A deficiency. A 6-year-old boy complained of difficulty in opening the eyelids. The ocular conjunctiva was hyperemic and keratinized with purulent ocular (eye) discharge. Both corneas showed epithelial defects with hypopyon. The serum vitamin A level was ≤5 IU/dL (normal 97-316), leading
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Orbital Perivascular Epithelioid Cell Tumor in a Case of Tuberous Sclerosis. Case Rep. Ophthalmol. Pub Date : 2023-07-07 Shaikha H Aljneibi,Aisha A Aldhanhani,Khaled Abuhaleeqa,Francesco Pichi
The aim of the study was to report a case of orbital perivascular epithelioid cell tumor (PEComa) in a known diagnosed patient of tuberous sclerosis and retinal astrocytic hamartoma. 43-year-old female presented with rapid progressive painful proptosis in the left eye, also reported new mass growing in her upper back. The patient past medical history is significant for left renal angiomyolipoma and
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Ocular Syphilis with Retinal and Disc Neovascularization Treated with Bevacizumab: A Case Report. Case Rep. Ophthalmol. Pub Date : 2023-07-03 Lucia Comastri,Milagros Heredia,Diego Bar,Guillermo Iribarren,Ariel Schlaen
We report the findings observed in a young woman with ocular syphilis complicated with retinal and disc neovascularization successfully treated with intravitreal bevacizumab. Fluorescein angiography revealed in both eyes intense hyperfluorescence at the level of the disc, multifocal venous wall staining, multifocal paravenous leakage, multiple peripheral saccular venular dilations, diffuse retinal
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Left Superior Homonymous Quadrantanopia due to Giant Virchow-Robin Space. Case Rep. Ophthalmol. Pub Date : 2023-07-03 Michelle Lim,Jonathan A Micieli
A 51-year-old man was referred by his optometrist for an incidental finding of a visual field defect. Humphrey 24-2 SITA-Fast visual field testing revealed a left superior homonymous quadrantanopia, and magnetic resonance imaging of the brain showed a 2.0 × 0.5-cm oblong-shaped cerebrospinal fluid space posterior to the right basal ganglia. This space coursed close to the lateral geniculate body and
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Peripheral Ophthalmic Artery Aneurysm Associated with Multifocal Intracranial and Extracranial Aneurysms: Case Report and Literature Review. Case Rep. Ophthalmol. Pub Date : 2023-06-22 Zixin Hong,Jonathan E Noonan,Peter J Mitchell,Thomas G Hardy
Peripheral ophthalmic artery aneurysm is a rare disease entity. We review the relevant literature and report a case of fusiform aneurysm involving the entire intraorbital ophthalmic artery in association with multiple intracranial and extracranial aneurysms, diagnosed on digital subtraction angiography. The patient suffered irreversible blindness secondary to compressive optic neuropathy which did
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Management of Coats-Like Disease in a Forty-Four-Year-Old Patient with FSHD Type I. Case Rep. Ophthalmol. Pub Date : 2023-06-16 Francesca Bruzzone,Tim Beltraminelli,Alex Casanova,Moreno Menghini
A forty-four-year-old female patient known for FSHD type I, with unremarkable past ocular history, complained of progressive visual acuity deterioration during a routine ophthalmological visit. Best-corrected visual acuity (BCVA) was 1.0 decimal Snellen equivalent bilaterally. Dilated fundus examination showed evidence of retinal Coats-like disease in the left eye, while the right eye showed significant