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A Study of the Effectiveness of Mobile Health Application in A Self-management Intervention for Kidney Transplant Patients. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-09-01 Xiuyuan Xie,Xuejing Wang,Anqi Li,Yanhong Yan,Ting Lu,Yue Wu,Zheng Lin
INTRODUCTION With the development of information technology in medical treatment, mobile medical treatment has become a new way to seek treatment, follow-up, extended care, popular science, disease prevention and access to disease expertise. The application of mobile medical treatment is relatively mature in the management of chronic diseases. Currently, mobile medical intervention is also introduced
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A Hematopoietic Stem Cell Transplant Recipient with Nephrotic Syndrome and Immune Complex Deposits in Tubular Basement Membrane: A Rare Case Report. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-09-01 Niloofar Nematollahi,Monir Sadat Hakemi,Farnaz Tavakoli,Fatemeh Nili
Following allogenic hematopoietic stem cell transplantation (HSCT), graft-versus-host disease (GVHD) may develop which may affect several organs. Although the presence of nephrotic syndrome after HSCT is rare, sometimes it occurs in the setting of GVHD. The most common histological finding on kidney biopsy of patients with proteinuria owing to GVHD is membranous glomerulonephritis (MGN). However, reports
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Long-term Outcomes in Patients with Membranous Nephropathy: A Retrospective Cohort Study in Iran. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-09-01 Seyed Mehdi Hoseini,Neda Najafi,Mitra Mehrazma,Reihane Chegini,Mandana Rahimi,Mohsen Vahedi,Shahrzad Ossareh
INTRODUCTION Membranous nephropathy (MN) has variable clinical outcomes, ranging from spontaneous remission to slow progression to kidney failure. Since the clinical outcomes of MN have not been studied in a large sample size in Iran, this study was designed to evaluate the outcome of patients diagnosed with MN at Hasheminejad Kidney Center (HKC), Tehran. METHODS In this retrospective cohort study
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COVID-19 Associated Acute Kidney Injury: The Incidence and Associated Factors in Different KDIGO Stages Among the Hospitalized Patients. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-09-01 Jamshid Roozbeh,Anahid Hamidianjahromi,Aida Doostkam,Leila Malekmakan,Abolfazl Dorraninejad
INTRODUCTION Acute kidney injury (AKI) is the most common reported renal complication associated with COVID-19. In this study, we evaluated the frequency of AKI, the predisposing factors, and its impact on the patient's outcomes in COVID-19. METHODS By collecting retrospective data, we conducted a crosssectional study on hospitalized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected
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The Effect of Moringa Isothiocyanate-1 on Renal Damage in Diabetic Nephropathy. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-09-01 Lijing Chen,Deyong Fan,Fei Guo,Jiuhong Deng,Linlin Fu
INTRODUCTION Diabetic nephropathy (DN) is the most common clinical complication of diabetes mellitus. Moringa isothiocyanate-1 (MIC-1) is effective in the treatment of diabetes mellitus, but its mechanism of action in DN remains obscure. This research specifically probed the role of MIC-1 in modulating renal injury in DN. METHODS Six db/m mice were assigned to control group and twelve db/db mice were
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Physical Exercise of Patients on Hemodialysis, Optimistic or Pessimistic. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-09-01 Radojica V Stolic,Natasa Zdravkovic,Vekoslav Mitrovic,Andrijana Karanovic,Dragisa Rasic,Kristina Bulatovic
Chronic kidney disease leads to significant functional limitations and severe disability, which requires the application of an appropriate physical rehabilitation strategy that helps patients achieve social well-being and significant health benefits. Data sources MEDLINE, PubMed, Google Scholar and Web of Science were electronically searched, by using search terms: physical exercise, hemodialysis,
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Impact of Nanographene Oxide on Cisplatin Induced Acute Kidney Injury Managed by Stem Cells Therapy. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-09-01 Parvin Karimzadeh,Tahereh Foroutan,Mohsen Nafar,Sahar Kalavati
INTRODUCTION Graphene-based nanomaterials have shown some degrees of stem cell protection against cell death. Due to their distinctive function, the kidneys are exposed to many toxic substances. On the other hand, minor and trivial effects of stem cells have been reported for the treatment of acute kidney injury (AKI). Here, we explain the use of Graphene oxide (GO) for improving the efficacy of mesenchymal
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Correlation Between Serum Homocysteine Levels and Carotid Intima-media Thickening in Hemodialysis Patients. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-07-01 Alireza Soleimani,Seyed Hamed Tabatabaei,Maryam Soleimani,Mehrdad Sinaeinejad,Fereshteh Ghazvini,Seyed Zia Tabatabaei,Hossein Mofidi,Mehdi Kashani,Seyyed Taher Seyyed Mahmoudi
NTRODUCTION Hyperhomocysteinemia is an important risk factor for cardiovascular disease in ESKD patients. Homocysteine, as an inflammatory factor, and carotid intima-media thickness (CIMT) could predict atherosclerosis in hemodialysis-treated ESKD patients. In this regard, the present study was conducted to investigate serum homocysteine level and its relationship with internal carotid intima thickness
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Comparison Between Vancomycin Lock and Taurolock Solution for the Prevention of Catheter- related Infections in Hemodialysis Patients, A Multicenter Study. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-07-01 Amir Ahmad Nassiri,Azadeh Ahmadi Koomleh,Tahereh Sabaghian,Maryam Delgosha,Monir Sadat Hakemi
INTRODUCTION Central venous catheters, frequently used in patients undergoing hemodialysis, place the patients at high risk of catheter-related infections. Therefore, it is essential to select the optimal prevention protocol for these infections. This study aims to compare the efficacy of the Taurolock solution and antibiotic lock in preventing tunneled catheter (permcath) related infections. METHODS
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Determinants of Sarcopenia in Elderly Patients with Chronic Kidney Disease. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-07-01 Jianming Zhang,Lei Ran,Yapu Zhang,Li Guo,Youlan Gong,Xiaoxi Wu,Lei Wang
INTRODUCTION This study was conducted to determine the factors affecting the development of sarcopenias in elderly patients with chronic kidney disease (CKD), in order to provide future clinical reference and guidance in preventing the occurrence of sarcopenias in patients with CKD. METHODS We included 116 CKD patients admitted to affiliated Hospital of Hebei University for retrospective analysis between
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Preventive Effects of Nicorandil and Atorvastatin in Contrastinduced Nephropathy in Patients with Renal Dysfunction Undergoing Coronary Artery Angiography: A Double Blind, Randomized, Controlled Clinical Trial. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-07-01 Sousan Mohammadi Kebar,Elham Atighi,Saeed Hosseninia,Behzad Babapour
INTRODUCTIONS Contrast-induced nephropathy (CIN) is an important issue in patients with cardiovascular disorders undergoing angiography, especially in patients with kidney failure. The purpose of the present study was to compare the preventive effects of nicorandil and atorvastatin on the incidence of CIN in patients with chronic kidney disease (CKD). METHODS In this clinical trial study, 270 patients
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Montelukast Is Effective in Treating Rhabdomyolysis Due to Intoxication: A Randomized Clinical Trial. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-07-01 Mohsen Bijandi,Mitra Rahimi,Shahin Shadnia,Babak Mostafazadeh,Latif Gachkar,Maral Ramezani,Peyman Erfan Talab Evini
INTRODUCTION Rhabdomyolysis is a clinical syndrome accompanied with biochemical changes that is diagnosed in some patients with acute chemical or drug poisoning. In this regard, the present study aimed to evaluate the effects of Montelukast in the treatment of intoxication-induced rhabdomyolysis. METHODS This single-blind randomized clinical trial study was conducted in Loghman Hakim Hospital from
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Study of The Relationship Between 24-hour Urine Protein Excretion Rate and Protein/Creatinine Ratio in Random Urine Specimen of Women with Preeclampsia. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-07-01 Farahnaz Farzaneh,Ali Alidadi,Abolfazl Payandeh,Marziyeh Ajdary,Neda Eslahi,Ali Pahlavanravi,Shahla Mirgaloybayat
INTRODUCTION Early diagnosis and management of preeclampsia are very important to reduce fetal and maternal complications. In this study, we examined the ratio of protein to creatinine in a random urine sample and its relationship to the rate of 24-hour urine protein excretion for quick detection and prompt management of this condition in women with preeclampsia. METHODS In this descriptive-analytical
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Sodium-Glucose Cotransporter-2 Inhibitors in Patients with Non-diabetic Chronic Kidney Disease: A Systematic Review. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-07-01 Nakisa Rasaei,Leila Malekmakan,Ghazal Gholamabbas,Mina Mashayekh,Farshad Hadianfard,Mahsa Torabi
Sodium-glucose cotransporter-2 (SGLT2) inhibitors modulate kidney function in diabetic chronic kidney disease trials. Furthermore, recent studies have showed their effect on kidney dysfunction in non-diabetic chronic kidney disease (CKD). Here, we focus on the impact of SGLT2 inhibitors on some renal parameters in nondiabetic CKD by discussing completed and ongoing trials. Different databases and search
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The Renal Histopathological Findings in Patients with Renal Allograft Dysfunction: A Retrospective Single Center Study. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-05-01 Mana Mohammadi Afrakoti,Amir Ahmad Nassiri,Monir Sadat Hakemi,Arya Afroughe,Mohammad Reza Ganji
INTRODUCTION Despite many advances in the development of knowledge and application of new immunosuppressive medications over the past two decades, the improvement has only been seen in the short-term outcome of kidney transplantation while the long-term survival of kidney transplantation has not significantly improved. Allograft kidney biopsy may help to determine the causes of allograft dysfunction
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Relationship Between Malnutrition Inflammation Score and Dietary Fat Quality Indices with Cardiovascular Diseases in Hemodialysis Patients. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-05-01 Zahra Mirali,Golnaz Majdizadeh,Mahsa Baghbani,Shahrzad Ossareh,Nooshin Dalili,Ariyo Movahedi
INTRODUCTIONS Malnutrition-inflammation-atherosclerosis is an independent risk factor and the most significant cause of death in dialysis patients, accounting for about 50% of deaths in the population. Moreover, the high incidence of cardiovascular-induced mortality in patients with end-stage kidney disease cannot be fully attributed to cardiovascular (CVD) risk factors only. Studies suggest that risk
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Estimating Patient Survival and Risk of End-Stage Kidney Disease in Patients With Autosomal Dominant Polycystic Kidney Disease in Iran. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-05-01 Tahereh Malakoutian,Shahrokh Izadi,Parisa Honarpisheh,Seyed Morteza Bagheri,Negin Saffarzadeh,Hounaz Akbari
INTRODUCTION Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary kidney disease that can affect several organs. The clinical course of the disease varies among patients; some never become symptomatic, and others reach end-stage kidney disease (ESKD) in the 5th decade of their life. METHODS This historical cohort study was conducted on ADPKD patients to investigate kidney and patient
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Excretion of Nitrogenous Waste Products from the Intestinal Fluid Simulator Using Super Absorbent Polymer: A New Generation Dialysis. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-05-01 Behzad Abedi,Hamid Tayebi Khosroshahi
INTRODUCTION End stage kidney disease (ESKD) is a life-threatening disorder, which results from loss of function of more than 75% of renal tissue. Many treatment modalities have been attempted for this disease, but only renal transplantation, hemodialysis and peritoneal dialysis have been practically accepted. Each of these methods have certain disadvantages, therefore other treatment modalities are
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Serum Levels of Indoxyl Sulfate and P-cresol in Type II Diabetic Patients With and Without Nephropathy. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-05-01 Roghayeh Oladi-Ghadikolaei,Akbar Aliasgharzadeh,Ali Shayanfar,Jafar Soleymani,Milad Moradi,Abolghasem Jouyban,Hamid Tayebi Khosroshahi
INTRODUCTION Indoxyl sulfate (IS) and para-cresol (p-cresol) are uremic toxins with high protein bonding index that accumulate in the body with decreasing kidney function. The main purpose of the current investigation was to compare the concentration of p-cresol and IS in serum of the type II diabetic individuals with and without nephropathy. METHODS Fifty-five patients with type II diabetes mellitus
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Allicin Protects Renal Function, Improves Oxidative Stress and Lipid Peroxidation in Rats with Chronic Renal Failure. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-05-01 Ningning Xu,Weinan Han,Guoping Yun,Lulu Shi
INTRODUCTION The research was an attempt to explore the potential impact of allicin on lipid peroxidation and oxidative stress in rats diagnosed with chronic kidney disease (CKD), and to determine its underlying mechanism. METHODS Sixty rats were randomly divided into sham-operated, modelling, and allicin low, medium, and high dose groups. The histopathological structure of the kidney was observed
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Efficacy and Safety of Angiotensin Receptor Blockers in Pediatric Patients (Aged 6 to 18) with Hypertension: A Systematic Review. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-05-01 Sahar Bassiri,Elham Bakhtiari,Nafise Ghaffarian,Nasrin Moazzen,Yalda Ravanshad,Anoush Azarfar
Angiotensin receptor blockers (ARBs) are commonly prescribed in pediatric hypertension because of the fundamental role of the renin-angiotensin-aldosterone system in the pathogenesis of hypertension. We, therefore, aimed to systematically review articles that investigated efficacy and safety of ARB agents in the pediatric population aged over six years. To do so, the databases of Web of Science, PubMed/MEDLINE
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Predictor Factors of Return to Work in Workers with Kidney Transplantation in Iran: A Retrospective Cohort Study. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-03-01 Elaheh Kabir Mokamelkhah,Tahereh Malakoutian,Saber Mohammadi,Negin Kassiri,Niloofar Safaei,Afshin Zarafshar
INTRODUCTION Return to work after a kidney transplantation in a previously functioning person is determined by a number of medical and non-medical factors. In this regard, this study was to investigate the factors that influence return to work in kidney transplant recipients. METHODS This retrospective cohort study was conducted in patients with kidney transplant in the main nephrology center in Tehran
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Association of Metabolic Syndrome and Hyperuricemia in the Recipients of Kidney Transplants: A Single-Center Study. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-03-01 Maryam Salari,Mohammad Ali Yaghoubi,Maryam Miri,Hassan Mehrad-Majd,Maryam Hami
INTRODUCTION The prevalence of hyperuricemia shows an increasing trend among kidney transplant recipients. The association between metabolic syndrome and hyperuricemia among the recipients of kidney transplants may consequently lead to reduction in graft survival. In this regard, the present study aimed at comparing the kidney transplant recipients with and without metabolic syndrome in terms of the
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Obesity and the Risk of Developing Kidney Stones: A Systematic Review and Meta-analysis. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-03-01 Elham Emami,Saeid Heidari-Soureshjani,Atrin Oroojeni Mohammadjavad,Catherine Mt Sherwin
Obesity is a growing problem that causes various metabolic disorders and organ dysfunction. The present systematic review and meta-analysis examined the impact of obesity on the risk of kidney stones. This meta-analysis was designed according to PRISMA guidelines. This extensive search was conducted on June 6, 2022, using relevant keywords in databases including PubMed, Web of Science, EMBASE, and
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Glucocorticoid Receptor Polymorphisms and Avascular Osteonecrosis After Kidney Transplantation. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-03-01 Jalal Etemadi,Mohammad Reza Jafari Nakhjavani,Saber Sepehri,Roza Motavalli,Seyed Sina Hejazian,Seyyedeh Mina Hejazain,Sima Abediazar,Sepideh Zununi Vahed
INTRODUCTION Glucocorticoids (GCs) are commonly prescribed as immunosuppressive agents after kidney transplantation and their most common non-traumatic adverse effect is Avascular Necrosis (AVN) of the femoral head. In this regard, this study aimed to evaluate the glucocorticoid receptor (GR) polymorphisms among kidney transplant recipients and their potential role as a risk factor for the incidence
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Prevalence and Prognosis of Post-transplant Glomerulonephritis in Kidney Transplant Biopsies, A Single- Center Report. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-03-01 Roghayeh Jafari,Mitra Mehrazma,Mohsen Vahedi,Shahrzad Ossareh
INTRODUCTION Recurrence of glomerulonephritis (GN) after kidney transplant (Tx) may be associated with allograft loss. This study aimed to evaluate the frequency and prognosis of de novo or recurrent post-Tx GN. METHODS We reviewed 1305 kidney Tx biopsy samples obtained between 2006 and 2020. The biopsy specimens were divided into post-Tx GN (recurrent or de novo) and control groups (i.e., no detectable
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Urinary MicroRNAs, Possible Biomarkers for Early Detection of Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD). Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-03-01 Yaghoob Ghasemi,Alireza Mardomi,Effat Alizadeh,Hamid Tayebi Khosroshahi
INTRODUCTION Autosomal dominant polycystic kidney disease (ADPKD) is a prevalent renal disorder that causes abnormal growth of renal epithelial cells. The excessive expansion of renal epithelial cells can lead to cyst formation that is associated with serious renal complications. The early diagnosis of ADPKD makes the control of the disease somehow attainable. Regarding the diagnostic potential of
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Effect of Pre-dialysis Serum Sodium Measurement on Reduction of Hemodialysis Complications. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-03-01 Khadijeh Yazdi,Sara Saadatmand,Einollah Mollai,Maliheh Abbasi,Majid Dastorani,Saeid Amirkhanlou
INTRODUCTION Despite great advances in hemodialysis, complications during dialysis remain in force. Accurate assessment of dry weight is a determining factor in the prevention of hemodialysis complications. This study is designed to evaluate the effect of adjustment of ultrafiltration rate, on hemodialysis complications, based on dry weight calculation, by measuring the pre-dialysis serum sodium. METHODS
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Carotid Intima-media Thickness in Hemodialysis Patients and Related Biochemical and Clinical Factors. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-01-01 Azita Zafar Mohtashami,Babak Hadian,Mohammad Heidarian,Parisa Khalili
INTRODUCTION Cardiovascular complications are the most frequent cause of death in chronic kidney disease that happens due to both general and uremic risk factors. Recently, the medical literature has declared the carotid artery intima-media thickness to be an indicator for predicting cardiovascular diseases. METHODS This paper is an attempt to introduce an analytical cross-sectional study of 128 hemodialysis
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Contrast-induced Nephropathy in Kidney Transplant Recipients: A Single-center Experience. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-01-01 Osama A Gheith,Ayman M Nagib,Medhat A Halim,Tarek Mahmoud,Prasad Nair,Hasaneen Abo-Atya,Mohamed Shaker,Mohamed Mostafa,Hosam Attia,Torki Alotaibi
INTRODUCTION Data regarding contrast-induced nephropathy (CIN) in kidney transplant (KT) recipients are scarce despite the distinct risk factors such as the use of immunosuppressive agents, sympathetic denervation, glomerular hyperfiltration, and high prevalence of the cardiovascular disease. This study aimed to determine the prevalence of CIN in KT recipients who received low-osmolality iodine-based
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Measured GFR in Donor Selection, to Do or Not to Do? That is the Question. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-01-01 Shiva Samavat,Homa Masrour,Azadeh Ahmadikoomleh,Ali Reza Khoshdel,Mohsen Nafar,Nooshin Dalili,Ahmad Firouzan,Fatemeh Poorrezagholi,Fariba Samadian,Samaneh Hoseinzadeh
INTRODUCTION The accurate assessment of the pre-donation glomerular filtration rate (GFR) is a crucial step in donor selection. We conducted a prospective cross-sectional study to identify the best equation to estimate GFR and the necessity of a radio-nuclear scan in GFR evaluation. METHODS In this study, 154 potential donors were enrolled, and GFR equations (the MDRD study, the CKD-EPI study, and
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Acute Kidney Injury in Pediatric Patients with COVID-19; Clinical Features and Outcome. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-01-01 Mahbubeh Mirzaee,Mahnaz Jamee,Masoumeh Mohkam,Fatemeh Abdollah Gorji,Mitra Khalili,Sedigheh Rafiei Tabatabaei,Abdollah Karimi,Shahnaz Armin,Roxana Mansour Ghanaie,Seyed Alireza Fahimzad,Zahra Pournasiri,Seyed Mohammad Taghi Hosseini Tabatabaei,Reza Dalirani,Nasrin Esfandiar,Mina Alibeik
INTRODUCTION Renal disorders have been reported as the underlying cause as well as complications of critical COVID-19 in pediatric patients. The purpose of this study was to investigate the pattern of kidney involvement, particularly acute kidney injury (AKI), among pediatric patients with COVID-19. METHODS In this prospective study, hospitalized pediatric patients with a clinical diagnosis of COVID-19
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Assessment of Urinary Level of Neutrophil Gelatinaseassociated Lipocalin (NAGL) in Children with Renal Scar Due to Vesicoureteral Reflux. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-01-01 Alireza Eskandarifar,Rama Naghshizadian,Adnan Tari
INTRODUCTION Renal scarring is a serious complications of urinary tract infection and vesicoureteral reflux (VUR). The dimercaptosuccinic acid (DMSA) scan is the gold standard method for diagnosing renal scars but is an expensive procedure that risks ionizing materials and is not available to everyone. Neutrophil gelatinase-associated lipocalin (NGAL) increases following inflammation, infection, and
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Roles of Clinical Features and Chest CT in Predicting the Outcomes of Hospitalized Patients with COVID-19 Developing AKI. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-01-01 Tahereh Sabaghian,Masoomeh Raoufi,Shekoofeh Yaghmaei,Omid Moradi,Azamalsadat Alavi,Hemmat Ebrat Balkhkanlou,Farnoosh Masbough,Ali Falsafi,Minoo Heidari Almasi
This research aimed to evaluate the clinical features and computed tomography (CT) scans associated with poor outcomes in COVID-19 patients with acute kidney injury (AKI). A total of 351 COVID-19 patients (100 AKI, 251 non-AKI) hospitalized at Imam Hossein Teaching Hospital affiliated to Shahid Beheshti University of Medical Sciences were included. To investigate the factors associated with in-hospital
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Prediction of Acute Kidney Injury by Fibroblast Growth Factor 23 (FGF-23) in Adult Patients, A Meta-analysis Study. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2023-01-01 Wei Tao,Shu-Wen Guo,Yu-Jie Fan,Feng Zheng
INTRODUCTION The aim of the current meta-analysis was to assess the predictive value of blood fibroblast growth factor 23 (FGF-23) for acute kidney injury (AKI) in adult patients. METHODS We retrieved relative publications from electronic databases including the Cochrane Library, PubMed, Google Scholar, Scopus, web of science, and Wanfang Data from their inception to Aug 2022. RESULTS This meta-analysis
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Recurrent Acute Kidney Injury Caused by Idiopathic Renal Hypouricemia: The First Report from Iran with A Novel Mutation. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-11-01 Bahman Bashardoust,Majid Hedayati
Numerous factors have been involved in exercise-induced acute kidney injury (EIAKI), such as using non-steroidal anti-inflammatory drugs following exercise and idiopathic renal hypouricemia (IRHUC). IRHUC is an autosomal recessive inherited disorder characterized by impaired tubular uric acid transfer, impaired reabsorption, and accelerated uric acid secretion. Some IRHUC patients have been shown to
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Challenging Issues in Diagnosis and Screening of BK Virus Nephropathy in Kidney Transplant Recipients, A Multicenter Experience in Iranian Population. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-11-01 Fatemeh Nili,Seyed Mohammadreza Khatami,Malihe Saberafsharian,Reza Shahsiah,Yadollah Shakiba,Golnar Seirafi,Yasaman Sadeghi,Maryam Miri,Reza Ataei,Maliheh Mohamadhoseini
INTRODUCTION BK virus nephropathy (BKVN) is an important complication of kidney transplantation and kidney biopsy remains the gold standard for its diagnosis. Urine/serum polymerase chain reaction (PCR) is a more sensitive diagnostic method, although it has some potential limitations. METHODS This study enrolled all kidney transplant recipients who underwent kidney transplant biopsy, collected from
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Chronic Kidney Disease in Isfahan Province, Action Plan for Screening in A Population-based Study. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-11-01 Firouzeh Moeinzadeh,Marjan Mansourian,Mojgan Mortazavi,Shiva Seirafian,Shahrzad Shahidi,Zahra Tasdighi,Sahar Vahdat,Shahram Taheri,Mohammad Hossein Rouhani,Mohammad Saleki,Mostafa Rezaei,Mohammad Hossein Masoudi,Zahra Zamani,Nahid Rafie
INTRODUCTION We intended to explore the prevalence of chronic kidney disease (CKD) and its different stages, as well as CKD associated variables in the adult population in Isfahan province, Iran. METHODS Adults aged ≥ 18 were recruited in a cross-sectional study from 2017 to 2019. Data including demographics, anthropometrics, and laboratory findings were collected from each subject. The equation of
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Antibody-mediated Rejection of Kidney Allografts Following COVID-19: A Report of Two Cases. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-11-01 Seyed Amirhossein Fazeli,Miralireza Takyar,Mahmoud Parvin,Abdolreza Haririan,Amirhesam Alirezaei
Increased risk of graft rejection could be the consequence of COVID-19 in kidney transplant recipients (KTRs). We report two cases of kidney transplant (KT) with stable graft function who experienced antibody-mediated rejection (ABMR) following recovery from COVID-19. It seems that reduced immunosuppression during the acute illness, is the main explanation for post-COVID-19 ABMR. However, the inflammatory
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Hemodynamic Profile of Patients with ESKD Referred to Heart Failure Department of Rajaie Heart Center, A Data from Right Heart Catheterization Registry. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-11-01 Leili Valizadeh,Hoda Raffiei Jelodar,Sepideh Taghavi,Ahmad Amin,Hamideh Khesali,Reza Ravanparsa,Marzieh Mirtajaddini,Razie Omidvar,Zahra Shafii,Nasim Naderi
INTRODUCTION Cardiovascular disorders are the leading cause of mortality and morbidity in patients with end-stage kidney disease (ESKD). We aimed to describe different patterns of cardiovascular abnormalities, the hemodynamics and the outcomes of ESKD patients referred to a tertiary center for heart failure programs, in detail. METHODS In this cohort, all ESKD patients who were referred by nephrologists
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Virulence Factors of Staphylococcus Aureus Hemolysin HLA and HLB Isolated from Catheters of Dialysis Patients Referred to Nikan Hospital in Tehran During the Spring and Summer of 2021. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-11-01 Mehrdad Jafari Fesharaki,Sara Alipanahi,Nazila Arbabsoleimani,Fatemeh Pourrezagholi,Zeinab Piravar
INTRODUCTION Staphylococcus aureus (S. aureus) is one of the most frequent causes of infection around the world. Insertion of intravascular catheter and formation of biofilms by methicillinresistant Staphylococcus aureus (MRSA) have contributed to the increased risk of infection, and morbidity and mortality rates. Biofilms formation on intravascular catheters and other medical devices are of major
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Revisiting the Management of Pediatric Kidney Transplants, A Multicenter Analysis Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-11-01 Farahnak Assadi,Nakysa Hooman,Abdolhassan Seyedzadeh,Anoush Azarfar,Elaheh Malakan Rad,Behnaz Bazargani,Arash Abasi,Mastaneh Moghtaderi,Afshin Safaeiasl,Nasrin Esfandiar,Ali Derakhsan,Hamidreza Badeli,Alireza Eskandarifar,Mojgan Mazaheri,Fatemeh Ghane Sharbaf
The newest Kidney Disease Improving Global Outcomes (KDIGO) guideline recommendations were investigated mainly for the care of adult kidney transplant recipients, but no guideline exists for the management of pediatric transplant recipients. This review provides update recommendations in the management of pediatric kidney transplantation. Four electronic databases, PubMed, EMBASE, Google Scholar, and
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Rapidly progressive IgA nephritis and sarcoidosis. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-09-01 Ivo Jelicic,Suzana Mladinov
Renal sarcoidosis frequently causes granulomatous interstitial nephritis, but clinically relevant nephritis is uncommon. IgA nephropathy caused by sarcoidosis is usually associated with milder stages of renal dysfunction, and only one case of rapidly progressive IgAN has been reported to date. We present an interesting case of a patient with a rapidly progressive form of IgA nephropathy caused by sarcoidosis
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Cilostazol-induced Acute Kidney Injury in A Patient With Diabetic Foot Ulcer: A Case Report and Review of Literature. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-09-01 Shahrzad Shahidi,Elham Kabiri Naeini,Sadegh Mazaheri-Tehrani
INTRODUCTION Cilostazol is an antiplatelet agent, that has been recently used as an adjunctive therapy in the management of diabetic foot ulcers. Headache, diarrhea, palpitations, and edema are reported as common side effects. CASE PRESENTATION A 53-year-old woman was admitted to hospital, with decreased urine output and increased serum creatinine level. She had taken Cilostazol for the first time
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Online Clearance Monitoring With Electrical Conductance (Dt/V) Versus Blood-driven (Kt/V) of Urea: A Compressional Study. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-09-01 Hamid Tayebi-Khosroshahi,Arman Ghahremanzadeh,Morteza Ghojazedeh,Jeiran Dehgan
INTRODUCTION The rates of morbidity and mortality in patients receiving routine hemodialysis have been demonstrated to be significantly affected by the dose of HD. As the national and international standards for determination of dialysis adequacy vary among countries, it is necessary to investigate the optimum criteria for HD adequacy. In this study, we aimed at comparing HD adequacy, through two methods
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The Correlation Between Copeptin and Volume Status in Chronic Hemodialysis Patients. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-09-01 Negar Sheikh Davoodi,Farzanehsadat Minoo
INTRODUCTION Currently There is no noninvasive chemical biomarker, available for evaluating volume status, in individuals with endstage kidney disease (ESKD). This study aimed to determine the relationship between copeptin level and volume status in hemodialysis patients. METHODS This clinical trial enrolled 84 patients with ESKD (Mean age ± SD: 54.31 ± 15.47) on maintenance hemodialysis (3-times weekly
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Clinical Outcomes of 141 Cases of Isolated Antenatal Hydronephrosis; An Observational Study. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-09-01 Abbas Madani,Elham Pourbakhtyaran,Fatemeh Sharifi,Masoumeh Mohkam,Mastaneh Alaei,Pooria Ahmadi
INTRODUCTION Hydronephrosis, a condition that is mostly congenital, is considered as the most common type of pediatric urinary tract disorder. The aim of this study was the evaluation of the prognosis and outcomes of hydronephrosis in cases of congenital hydronephrosis. METHODS In a cross-sectional study, run in a tertiary clinic of pediatric nephrology, from 2015 to 2020, patients with fetal hydronephrosis
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Value of Color Doppler Ultrasonography for Diagnosing Early Diabetic Nephropathy. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-09-01 Linshen Ke,Yanyan Guo,Xiuli Geng
INTRODUCTION Early diagnosis of diabetic nephropathy (DN), the leading cause of death in diabetic patients, is an important issue in preventing and reducing the disease burden for patients and the healthcare system. In this study, we aimed at investigating the value of color doppler ultrasonography in the diagnosis of early diabetic nephropathy (DN). METHODS Two hundred and thirty-eight diabetic patients
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The Epidemiological Characteristics and Outcome of COVID-19 in Patients Undergoing Peritoneal Dialysis: A Multi-center Study in Iran. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-09-01 Jalal Azmandian,Zahra Shafii,Shahrokh Ezzatzadegan Jahromi,Nader Nourimajalan,Shiva Seyrafian,Abdolamir Atapour,Shahnaz Atabak,Saeideh Mazloomzadeh,Zeinab Norouzi,Iraj Najafi
The pandemic of COVID-19 emerged in December 2019. Although numerous features of the illness have been investigated, the impact of disease on those patients with underlying diseases, is still a major problem. The aim of this multicenter, cohort study, was to determine the clinical manifestations of COVID-19 in peritoneal dialysis (PD) patients. Five hundred and five patients, receiving PD, were enrolled
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Effect of Vitamin D on Urinary Albumin Excretion in Diabetic Nephropathy Patients: A Meta-analysis of Randomized Controlled Trials. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-09-01 Lei He,Lin Zhou,Tian-Ya Zhao,Alexander Temple Witherspoon,Long Ouyang
It remains controversial, whether vitamin D reduces urinary albumin excretion in patients with diabetic nephropathy (DN). This metaanalysis was designed to evaluate the therapeutic effect of vitamin D, on urinary albumin excretion, in DN patients. Electronic databases, including PubMed, Embase, Web of Science, and Cochrane library were searched for randomized controlled trials (RCTs), regarding the
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Acute Cellular Rejection in A Kidney Transplant Recipient Following Vaccination with Inactivated SARS-CoV-2 Vaccine. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-07-01 Soumia Missoum,Mourad Lahmar,Ghalia Khellaf
SARS-CoV-2 vaccines are being administered worldwide. Most of the reported side effects are mild and self-limiting with few reported cases of severe adverse reactions. Here we report a case of acute cellular rejection in a kidney transplant recipient following vaccination with an inactivated SARS-CoV-2 vaccine. fifty- one years old man with autosomal dominant polycystic kidney disease, who had received
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Silica Urinary Stones: A Case Report and A Brief Review of Literature. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-07-01 Yasar Caliskan,Jonathan Buck,Lindsay Lombardo,Bahar Bastani
Silicate stones are extraordinarily rare in human beings, but when present, they are often associated with ingestion of Magnesium Trisilicate, an antacid medication. However, there have been few case reports of patients who developed silicate stones, without ingestion of Magnesium Trisilicate. Hereby, we present the case of a 67-year-old man who developed acute kidney injury due to obstructive uropathy
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Efficacy of Sinopharm® COVID-19 Vaccine in Hemodialysis Patients: A Preliminary Report. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-07-01 Amirhesam Alirezaei,Seyed Amirhossein Fazeli,Meysam Shafiei,Amirhossein Miladipour
INTRODUCTION SARS-CoV-2 infection have been reported to have a greater mortality rate in adults receiving dialysis, as compared to general population. Hence, vaccination is very important in this vulnerable population group, in order to achieve an acceptable level of immunity. The aim of this study was to compare the level of anti-SARS-CoV-2 anti-spike protein receptor-binding domain IgG neutralizing
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Study on the Relationship Between Peritoneal Dialysis Ultrafiltration Failure and Aquaporin 1, Aquaporin 3, and Vascular Endothelial Growth Factor A Expression. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-07-01 Yu Guigui,Wang Ying,Ji Lijun,Wang Feng,Li Feife
INTRODUCTION The aim of this study was to investigate the expression of aquaporin 1 (AQP-1), AQP-3 and vascular endothelial growth factor A (VEGF-A) in peritoneal tissues of patients without kidney disease, chronic kidney disease at stages 5 (CKD 5) and patients on prolonged peritoneal dialysis with ultrafiltration failure (PDUFF), and elucidate the possible mechanism of peritoneal dialysis ultrafiltration
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Comparison of Propofol-Fentanyl with Midazolam-Ketamine Combination in Pediatric Patients Undergoing Kidney Biopsy. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-07-01 Anoush Azarfar,Yalda Ravanshad,Mohaddeseh Golsorkhi,Elnaz Zahiri,Mohamad Gharavi Fard,Mohsen Akhondi,Alireza Ghodsi,Sahar Ravanshad
INTRODUCTION Kidney biopsy is a procedure of choice for the diagnosis of many kidney diseases. In children it is performed with the use of sedatives. The aim of this study was to compare the combination of propofol/fentanyl with midazolam/ketamine for sedation in pediatric patients undergoing kidney biopsy. METHODS In this double-blinded clinical trial, seventeen children, candidate of kidney biopsy
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Desmopressin Acetate in Percutaneous Ultrasound-Guided Native Kidney Biopsy in Patients with Reduced Kidney Function: A Double-Blind Randomized Controlled Trial. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-07-01 Shahab Aldin Sattari,Azita Shahoori,Heshmatollah Shahbazian,Leila Sabetnia,Asieh Aref,Ali Reza Sattari,Ali Ghorbani
INTRODUCTION Bleeding events are the most common complications after kidney biopsy. This study aims to evaluate the effect of desmopressin administration on bleeding complication, in native kidney biopsy candidates with reduced kidney function. METHODS This double-blind randomized clinical trial enrolled 18 to 80 years old patients with 15 < eGFR < 90 mL/min/ 1.73m² from July 2017 to August 2020. Patients
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Effect of Electrolyte Imbalance on Mortality and Late Acute Kidney Injury in Hospitalized COVID-19 Patients. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-07-01 Tahereh Sabaghian,Mohamadjavad Honarvar,Seyed Amir Ahmad Safavi-Naini,Arefe Sadat Sadeghi Fadaki,Mohamad Amin Pourhoseingholi,Hamidreza Hatamabadi
INTRODUCTION As a multisystem illness, Coronavirus disease 2019 (COVID-19) can damage different organs. This study investigated the effect of electrolyte imbalance (EI), with or without concomitant renal dysfunction, on the prognosis of COVID-19 in hospitalized patients. METHODS We evaluated 499 hospitalized patients with confirmed COVID-19, without a history of chronic kidney disease. The patients'
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Effect of Calcium-based Phosphate Binders Versus Sevelamer on Mortality of Patients with Hemodialysis: A Meta-analysis. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-07-01 Poxuan Zhang,Shengmei Sang,Jinlan Huang,Sujuan Feng,Caiyun Feng,Rong Wang
Chronic kidney disease is a public health problem. The purpose of this study was to compare the effects of sevelamer and calciumbased binders on mortality of hemodialysis patients. PubMed, EMBASE and Web of Science were searched for related articles published before May 14, 2020. We included six studies with 43330 participants, of which 21147 and 22183 received calciumbased phosphate binders and sevelamer
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The Association Between Plasma MicroRNA-451 Expression Levels and Chronic Kidney Disease in Children with β-Thalassemia Major. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-05-01 Heba Mostafa Ahmed,Dina Badea Georgy,Mohamed Hussein Meabed,Rehab Muhammad Abd El Kareem,Osama Ezzat Botrous
INTRODUCTION Patients with β -thalassemia major (β -TM) had a high rate of glomerular dysfunction due to chronic anemia, iron overload, and chelation therapy. There is also evidence of proximal tubular damage, as almost all patients have various amounts of proteinuria. MicroRNAs are non-coding RNA molecules that regulate gene expression. In diabetes, a relative increase in renal microRNA-451 appeared
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A Novel Mutation in CLDN16 Gene Causing Familial Hypomagnesemia, Hypercalciuria, Nephrocalcinosis in An Iranian Family. Iran. J. Kidney Dis. (IF 1.3) Pub Date : 2022-05-01 Tahereh Malakoutian,Bahareh Madadi,Siamak Saber
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is a rare autosomal recessive disorder that is characterized by renal magnesium wasting, hypercalciuria and eventually kidney failure which mostly affects children and young aged adults. Mutation of genes of claudin-16 and claudin-19 are involved in the pathogenesis of this disorder, which leads to renal magnesium and calcium