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Papillary Thyroid Carcinoma with Intracytoplasmic Lumina: A Diagnostic Pitfall on Aspiration Cytology of a Metastatic Site. J. Cytol. (IF 1.3) Pub Date : 2023-08-14 Neeta Kumar,Ruchika Gupta,Sanjay Gupta
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The Structural Profile of HPV 18 in Terms of Chromosomal and Nuclear Degenerative Changes and the Ratio of Nucleus/Cytoplasm on Liquid based Cervical Cells. J. Cytol. (IF 1.3) Pub Date : 2023-08-14 Zehra Safi Oz,Figen Barut,Furuzan Kokturk,Banu Dogan Gun
Background HPV 18 is one of the important oncogenic types. HPV 18 is generally evaluated together with HPV 16 and/or high-risk HPV types in light microscopic studies. The purpose of this study was to evaluate the impact of only HPV 18 on the nucleus/cytoplasm ratio, and chromosomal and nuclear degenerative changes in liquid-based samples. Materials and Methods Eighty liquid-based cervical samples were
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The Similarities and Differences between Liquid-based and Conventional Methods in Evaluation of Thyroid Fine Needle Aspiration Cytologies. J. Cytol. (IF 1.3) Pub Date : 2023-08-14 Mehmet Özer,Selver Özekinci
Aims Thyroid nodules are one of the most frequent medical issues in endocrinology in our country and around the world. The appropriate evaluation of the nodule is critical in the management of patients. Fine needle aspiration cytology (FNAC) is one of the most accurate tools for evaluating these nodules. Conventional and liquid-based (LB) methods are available for thyroid FNAC. In this paper, we aim
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Comparative Analysis of Conventional Cytology and Liquid-Based Cytology in the Detection of Carcinoma Cervix and its Precursor Lesions. J. Cytol. (IF 1.3) Pub Date : 2023-08-14 Yashika Maheshwari,Uma Handa,Phiza Aggarwal,Bharti Goel
Context The conventional smears (CS) and Liquid based cytology (LBC) are important tools to detect carcinoma cervix and its precursor lesions. Aims The present study was done to compare the cytomorphological features of cervical lesions using both techniques and compare with the histopathological diagnosis. Settings and Design This was a prospective observational study over a period of 1.5 years at
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Study of Extramedullary Lymphoblastic Lymphoma (LBL) Diagnosed by Flowcytometric Immunophenotyping (FCI) on Fine Needle Aspirate (FNA) Sample-A Case Series of 18 Cases. J. Cytol. (IF 1.3) Pub Date : 2023-08-14 Manjiri M Makde,Purnima M Kodate,Meherbano M Kamal,Vrushali Shroff,Jayashree R Tijare,Dinkar T Kumbhalkar
Background Lymphoblastic lymphoma (LBL) accounts for about 2% of all lymphomas. Recognition of T/B-LBL albeit of their rareness is very important as they present as localized diseases with low tumor burden. They can present both at nodal and extranodal sites. Limitation of diagnosis and classification of lymphoma on fine needle aspirate (FNA) can be minimized by clubbing it with flowcytometric immunophenotyping
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The Role of Novel Tiered Reporting System in Serous Fluid Cytology and Risk of Malignancy Assessment: A Retrospective Study in a Tertiary Care Center. J. Cytol. (IF 1.3) Pub Date : 2023-08-14 Soumya Alashetty,Balu Sadasivan,Priya Dharmalingam,Nethra Rajagopal,Lucas Kavya,Malathi M Pai
Background Serous effusion cytology (SEC) reporting is important for the management of the cancer patient. The International System for Reporting Serous Fluid Cytology (ISRSFC) provides tiered reporting terminology to standardize practice, looking into the risk of malignancy (MAL) for each category. In this study, we have assessed the utility of the ISRSFC and reported our experience at a tertiary
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Cytological Diagnosis of Castleman Disease by Endoscopic Ultrasound Guided Fine Needle Aspiration. J. Cytol. (IF 1.3) Pub Date : 2023-08-14 Vikram Bhatia,Satender Pal Singh,Ajay Kumar Mishra,Indira Rath,Meghana Prabhu,Chhagan Bihari
Castleman disease is a nonmalignant, lymphoproliferative disorder. Unicentric disease type involves a single enlarged lymph node or nodal regions, and multicentric disease involves multiple lymph node site involvement. We present a case of 26-year-old young female presented to outpatient with complaint of generalized weakness and abdominal pain for last 2 months. Her imaging included positron emission
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Plasmacytoid Cells in Aspiration Smears of the Breast: Every Time a New Surprise. J. Cytol. (IF 1.3) Pub Date : 2023-08-14 Arundhathi Shankaralingappa,Poongodi Rajagopal,Michael L Anthony
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Heat Induced Processing of Cellblocks with Significant Reduction in Overall Turn Around Time. J. Cytol. (IF 1.3) Pub Date : 2023-08-14 Suhas Dhende,Saleem Pathuthara,Neelam Prabhudesai,Dipak Shinde,Nupur Karnik,Kedar Deodhar
Introduction Cellblock (CB) with immunohistochemistry (IHC) is practically indispensable in the diagnostic workup of serous effusions; however, CB requires a minimum of 15-20 h for routine histopathological processing. A reduction in processing time can expedite a faster diagnosis. Aim This study was undertaken to evaluate the utility of the heat-induced CB (HICB) technique. Material and Methods Two
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Bronchoalveolar Lavage in Diagnostic Evaluation of Pulmonary Diseases- An Institutional Experience. J. Cytol. (IF 1.3) Pub Date : 2023-05-22 Swalaha Sadaf Siddiqui,Tanya Sharma,Alkesh Kumar Khurana,Abhishek Goyal,Deepti Joshi,Garima Goel,Ujjawal Khurana,Neelkamal Kapoor
Background Bronchoalveolar lavage (BAL) is a widely accepted investigative tool for the diagnosis of pulmonary lesions. This study was done to find out the usefulness of BAL in diagnosis of pulmonary lesions from central Indian patient population. Methods A cross-sectional prospective study was performed over a period of three years. All the BAL specimens of patients presenting to Department of Pulmonary
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Quality and Performance of Papanicolaou Test using the Clinical and Laboratory Standards Institute (CLSI) EP12-A2 Guidelines: A Single-Center Study in Peru. J. Cytol. (IF 1.3) Pub Date : 2023-05-22 Jeel Moya-Salazar,Jennifer Huarcaya,Diana Vazquéz,Víctor Rojas-Zumaran,Hans Contreras-Pulache
Context Quality assurance in cervical cytology is based on the cyto-histological correlation that is performed in several countries even without standardized protocols. Aims To evaluate the quality of the Pap smear with the Clinical and Laboratory Standards Institute (CLSI) EP12-A2 guideline in a Peruvian hospital. Settings and Design This prospective study was carried out at tertiary care national
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Cytological Diagnosis of Pilomatrixoma and its Diagnostic Pitfalls. J. Cytol. (IF 1.3) Pub Date : 2023-05-22 Sabina Khan,Inara Abeer,Musharraf Husain,Sujata Jetley
Background Pilomatrixoma (PMX) is a relatively uncommon benign cutaneous neoplasm arising from skin adnexa. It presents as a subcutaneous asymptomatic nodule mostly in the head and neck region and is frequently misdiagnosed by the clinicians. Although easily diagnosed on histopathology, the cytologic features of PMX are less distinctive, depending on the stage and evolution of disease and may mimic
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A Study of Cytomorphological Spectrum of Head and Neck Lesions in Pediatric Age Group. J. Cytol. (IF 1.3) Pub Date : 2023-05-22 Megha M Wadone,Meenakshi M Masgal,A M Anita,P S Rajesh
Introduction Fine Needle Aspiration Cytology (FNAC) is a well-established early diagnostic technique for evaluating mass lesions in adult patients. Now, FNAC in children is gaining acceptance and is used as a first-line investigation in diagnosis of pediatric lesions. Aims To analyze the cytomorphologic spectrum of head and neck lesions in pediatric age group with histopathological correlation wherever
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Utility of Indigenous Cytology Technique in the Diagnosis of Oral Cavity Lesions using Normal Saline as a Processing Fluid: A Comparative Study. J. Cytol. (IF 1.3) Pub Date : 2023-05-22 B N Kumarguru,M Lakshmi Narayana,G Urvashi,A S Ramaswamy
Background Oral cancer is a major health problem in developing countries. Cytology has been widely accepted as a tool in the early diagnosis of cancer. Objectives To evaluate the diagnostic utility of four different cytology techniques, that is, modified brush cytology (BR) technique, brush cytology cytocentrifugation (BRCC) technique, modified scrape cytology (SR) technique, and scrape cytology cytocentrifugation
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Positive Rate of Malignant Cells in Endometrial Cytology Samples of Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer Patients: A Systematic Review and Meta-Analysis. J. Cytol. (IF 1.3) Pub Date : 2023-05-22 Tiantian Wang,Yadi Bin,Lanbo Zhao,Qiling Li
To estimate the feasibility of diagnosing ovarian cancer, fallopian tube cancer, and primary peritoneal cancer through endometrial cytology, we performed a systematic review and meta-analysis to calculate the pooled positive rate of malignant cells in endometrial cytology samples. We queried PubMed, EMBASE, Medline, and Cochrane Central Register of Controlled Trails from inception to November 12, 2020
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Screening of Endometrial Cancer Related to Lynch Syndrome in China by Suction Curettage-Based Cytology and Histology: A Retrospective Study. J. Cytol. (IF 1.3) Pub Date : 2023-05-02 Bo Yang,Huiqin Guo,Guqun Shen
Objective To explore the feasibility of sampling Chinese patients by suction curettage for cytological and histological screening of endometrial cancer related to Lynch syndrome. Methods This retrospective study enrolled patients who underwent endometrial biopsy at our hospital between May 2018 and January 2019. Endometrial sampling (cytological and micro-histological specimens) was conducted by suction
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Diagnostic Value of Preparing Additional Liquid-Based Cytology Slides and Cell Blocks from Residue Material in Thyroid fine Needle Aspiration. J. Cytol. (IF 1.3) Pub Date : 2023-05-02 Senay Erdogan-Durmus,Zeynep B Erdem,Ozden Yulek
Background and Aims After liquid-based cytology (LBC) technique developed for cervical cytology, it has been used for nongynecological samples and has been very successful. It offers having extra slides of the samples for further examination and ancillary tests. Moreover, cell blocks can be formed from the residue material. The study aimed to evaluate the importance of preparing a second LBC slide
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Role of Bronchoscopic Cytology in Diagnosis of Pulmonary Lesions. J. Cytol. (IF 1.3) Pub Date : 2023-03-21 Anjali Rao Kedige,Udipi Shastri Dinesh
Objectives Respiratory cytology specimens such as bronchoalveolar lavage (BAL) and bronchial wash (BW) obtained using a fiberoptic bronchoscope are very useful in detecting or ruling out various inflammatory conditions, infections, and neoplastic lesions. A study was carried out to determine the usefulness of respiratory cytology in the diagnosis of pulmonary lesions and the limitations of cytology
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High-risk Human Papillomavirus (hrHPV) Prevalence and Genotype Distribution among Turkish Women. J. Cytol. (IF 1.3) Pub Date : 2023-03-20 Melin Gecer
Purpose This study aimed to determine the rates of distribution of high-risk HPV (hrHPV) genotypes according to cervical smear samples and biopsy results in a large sample of Turkish women. Methods The study was conducted with 4,503 healthy volunteer women aged 19-65 years. Samples of cervical smears were collected during the examination and liquid-based cytology was used for the Pap tests. The Bethesda
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Cytological Features of "Non-Invasive Follicular Tumour with Papillary like Nuclear Features" - A Single Institutional Experience in India. J. Cytol. (IF 1.3) Pub Date : 2023-03-13 K Amita,H B Rakshitha,M Sanjay,Prashantha Kalappa
Background The term noninvasive follicular tumor with papillary-like nuclear features (NIFTP) was introduced as a surrogate for noninvasive encapsulated follicular variant of papillary thyroid carcinoma with a defined set of histopathologic criteria. There are very few studies depicting the cytological cues for the diagnosis of NIFTP. The objective of the study was to determine the spectrum of cytological
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Fine Needle Aspiration Cytology of Maxillary Ameloblastoma: A Cytological Eye-Opener. J. Cytol. (IF 1.3) Pub Date : 2023-03-10 Akriti Jindal,Gargi Kapatia,Manjit K Rana,Nikhil Rajan,Utkarshni Khera
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Microcystic Meningioma - A Diagnostic Dilemma During Intraoperative Squash Smear Study. J. Cytol. (IF 1.3) Pub Date : 2023-02-15 Sukhpreet Kaur,Rahul Karode,Hanni V Gulwani
Background Meningiomas are generally slow-growing, benign, and non-infiltrating in nature. They are usually easy to diagnose cytologically if they are of the meningothelial type; however, they may cause diagnostic challenges when they manifest as unusual morphological variants, like the microcystic type. Because of the rarity of microcystic meningioma (MM), information on its cytological features is
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Role of Guided FNA in Gallbladder Cancer: A Retrospective 3-Year Study. J. Cytol. (IF 1.3) Pub Date : 2023-02-15 Surbhi Goyal,Garima Prasad,Dimple Chaudhary,Puja Sakhuja,Siddhartha Srivastava,Anil K Aggarwal
Background A majority of the patients with gall bladder cancer (GBCa) present at an advanced stage and have poor survival. The aim is to retrospectively study the role of guided FNA in the diagnosis of GBCa in a superspecialty institute and to describe the cytomorphologic spectrum of gall bladder (GB) lesions in the North Indian population. Materials and Methods All suspected cases of GBCa who underwent
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Analysis of Intraoperative Squash Cytology of Central Nervous System Lesions and its Correlation with Immunohistopathology and Radiology. J. Cytol. (IF 1.3) Pub Date : 2023-01-17 Shilpa Accamma Philip,Earla Lakshmi Bai,G J Vani Padmaja,Swarajya Kumari
Context Central nervous system lesions are diverse and remain one of the most challenging domains for neuropathologists. Intraoperative cytological diagnosis is now a universally accepted technique in diagnosis of central nervous system (CNS) lesions. Aims 1) To analyze and compare cytomorphological features of CNS lesions in intraoperative squash smears with histopathology, immunohistochemistry, and
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Evaluation of the Cytonucleomorphometric Parameters for Cases Diagnosed as Squamous Cell Abnormality on Conventional Cervico-Vaginal Pap Smears. J. Cytol. (IF 1.3) Pub Date : 2022-12-26 Satyam Mishra,Ujjawal Khurana,Neelkamal Kapoor,Ankur Joshi,Deepti Joshi
Background and Aim The natural history of cervical cancer is unique that it is preceded by a precancerous condition for a long time. Morphometry as a tool can be used in early and accurate diagnosis of these precancerous and cancerous lesions. The present study aims at assessing the utility of cellular and nuclear morphometry in differentiating squamous cell abnormality from benign conditions and also
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Immunocytochemical Evaluation of TTF-1, Napsin-A, and p-63 for Subtyping of Non-Small Cell Lung Carcinoma and Clinicopathological Correlation. J. Cytol. (IF 1.3) Pub Date : 2022-11-14 Tarun Sharma,Prajna Das,Ranjita Panigrahi,C Mohan Rao,Jayashree Rath
Background Carcinoma of lung is the most common cause of cancer-associated mortality worldwide. About 70% of lung cancer cases are unresectable and present in advanced stages. So, cytology and small core needle biopsy specimen are available for diagnostic as well as prognostication workup. Subtyping of non-small cell lung cancer (NSCLC) is essential for the treatment and further workup study. For this
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The Prevalence of Cervical HPV Infection and Genotype Distribution in 856,535 Chinese Women with Normal and Abnormal Cervical Lesions: A Systemic Review. J. Cytol. (IF 1.3) Pub Date : 2022-11-11 Yan-Qin Yu,Jin-Qi Hao,Maria J G Mendez,S Bangura Mohamed,Shi-Lan Fu,Fang-Hui Zhao,You-Lin Qiao
Cervical cancer is the commonest cancer affecting women worldwide. During the last decades, the incidence and mortality rates of cervical cancer have increased in China. This research aims to assess the overall and genotype-specific prevalence of the human papillomavirus (HPV) infection among Chinese women with normal cervix, considering age, and geographic location. We selected studies about HPV prevalence
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Accuracy of Bronchial Cytological Diagnosis in Lung Lesions in Comparison with Histopathology. J. Cytol. (IF 1.3) Pub Date : 2022-11-11 Shreya Goel,Sunil K Yeshvanth,Ritu Asnani,Divya Joshi
The incidence of lung cancer has been increasing in the recent years. Bronchial cytology using Papanicolaou society of cytopathology (PSC) system is an effective method for triaging patients. The present study attempts to evaluate the bronchial cytological diagnosis with histopathological correlation of lung lesions. Aims i. To study the cytological features of lung lesions. ii. To assess the sensitivity
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Diagnosis of Pleural Fluid Effusions by Cell Block and Pleural Biopsy - A Comparative Study. J. Cytol. (IF 1.3) Pub Date : 2022-11-08 S S Sabitha Rani,Immadi Sudhakar Vamshidhar,Nitin Ashok John,Jyoti John
Background Cytological smear and cell block are commonly used to diagnose pleural fluid effusion. However, there is a paucity of information in the literature where a comparison between a cytological smear and a cell block with corresponding pleural biopsy has been done. This study aimed to evaluate the accuracy of cytological smears, cell blocks, and pleural biopsy for the diagnosis of malignant tumors
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Comparison of Modified Ultrafast Giemsa Stain with the Standard May Grunwald Giemsa Stain in FNAC of Various Organs. J. Cytol. (IF 1.3) Pub Date : 2022-11-08 B Deepthi,Aruna K Prayaga,N Rukmangadha
Background The May-Grünwald Giemsa Stain is one of the preferred Romanwsky stains in studying cell morphology of air-dried smears with respect to cellular and nuclear size details and metachromatic extracellular ground with an approximate staining time of 20-30 min. A reduction in staining time and possible application of an ultrafast stain for rapid onsite evaluation (ROSE) of cytological material
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Liquid-Based Cytology in the Detection of Premalignant Lesions in Patients with "Atypia in Squamous Cells" in Conventional Cytology. J. Cytol. (IF 1.3) Pub Date : 2022-10-29 Lia Barrios,Yoled Vizcaíno,Ines Benedetti
Background The management of patients with "Atypical Squamous Cells" (ASC) in conventional papanicolaou smears (CPS) is based on the risk of high-grade squamous intraepithelial lesion (HSIL). The efficacy of liquid-based cytology (LBC) to detect this premalignant lesion is variable, with little evidence of its performance in Colombian patients. Aims The aim of this study is to determine the performance
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Alveolar Rhabdomyosarcoma with CD 56 Positivity: A Mimic of Extranodal NK/T Cell Lymphoma. J. Cytol. (IF 1.3) Pub Date : 2022-10-29 Uma Kumar,Abhijit Das,Rani Sahu,Pinky Kachhap
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Association of Peritoneal Cytology with Other Prognostic Factors in Endometrial Cancer. J. Cytol. (IF 1.3) Pub Date : 2022-10-28 Slobodan Maricic,Aljosa Mandic,Tijana Vasiljević,Bojana Gutic,Nemanja Stevanovic,Tamara Maksimovic
Purpose It is still debatable whether surgical staging of endometrial cancer (EC) should include sampling of peritoneal cytology (PC) and for what purpose this should be done. The aim of our study was to determine the significance of peritoneal cytology in EC and its association with other histological and clinical parameters. Methods This is a retrospective study that comprises of results from 357
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Reproducibility of the "International Academy of Cytology Yokohama System for Reporting Breast Cytology" - A Retrospective Analysis of 70 Cases. J. Cytol. (IF 1.3) Pub Date : 2022-10-28 Anup K Boler,Shreosee Roy,Ankita Chakraborty,Arghya Bandyopadhyay
Background Fine-needle aspiration cytology (FNAC) is the most practiced initial method for evaluation of breast lesions. The International Academy of Cytology Yokohama System for Reporting Breast (IAC YSRB) Fine-Needle Aspiration Biopsy Cytopathology has been developed to standardize the reporting system. However, literature available on the inter-observer reproducibility of 5 IAC YSRB categories is
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Diagnostic Accuracy and Agreement Between Inter- and Intra-Observers in the Absence of Clinical History for Liquid-Based Preparation of Gynecology Specimens. J. Cytol. (IF 1.3) Pub Date : 2022-08-17 Nur Amirah Roslan,Mohd Nazri Abu,Farid Ridhuan Ismail
Context The clinical history in cytology is the best source of information to ensure the accuracy of diagnosis, facilitating a slide observer to interpret and relate their findings in screening gynecology slides. Aims This study aims to evaluate the performance of slide observers to screen-blinded gynecology slides without providing any information on clinical history. Setting and Design A correlational
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Critical Analysis of Laboratory Requisition Forms Received in a Cytopathology Laboratory of a Tertiary Care Centre: An Audit and Review of Literature. J. Cytol. (IF 1.3) Pub Date : 2022-08-17 Shivali Sehgal,Sujata Jetley,Zeeba S Jairajpuri,Sabina Khan
Background A laboratory requisition form (LRF) is the main communication link between the laboratories and the clinicians. In a cytopathology laboratory, incomplete forms with inadequate information significantly impact the quality of the results and waste precious time of the lab. Aims The aim of this study was to audit the LRFs for adequacy of demographic and clinical data and to analyze the reasons
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Diagnosis of Lung Adenocarcinoma with Clear Cell Features in Pleural Effusion: Cytomorphologic Features, Immunocytochemical Studies, and Differential Diagnosis. J. Cytol. (IF 1.3) Pub Date : 2022-08-17 Senay Erdogan-Durmus,Ozden Yulek,Zeynep Betul Erdem
Clear cell adenocarcinoma (CCA) of the lungs is no longer referred to as a subtype in recent classifications of lung adenocarcinoma. Like signet ring features, clear cell features are regarded as cytological features rather than histological subtypes. Additionally, in serous fluids, adenocarcinoma metastasis with clear cell features is a diagnostic challenging entity due to other tumors that come to
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CSF Involvement by Nonhematolymphoid Malignancies: A Descriptive Study with Emphasis on Cytomorphological Clues. J. Cytol. (IF 1.3) Pub Date : 2022-08-17 Vidhya Vikashini Balasubramaniam,Saranya Mohan,Suganya Kuppovi Reddy,Jinkala Sree Rekha,Debasis Gochhait,Neelaiah Siddaraju
Introduction Detection of malignant cells in cerebrospinal fluid (CSF) samples in suspected cases of malignancy is critical for the management of patients. CSF involvement by nonhaematolymphoid malignancies is less common. We aimed to study the cytomorphologic characteristics of various nonhaematolymphoid malignancies in CSF. Methods A retrospective cytomorphological analysis of 27 CSF cytology smears
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The Indian Academy of Cytologists Guidelines for Reporting Serous Effusion (IACGRSE): An Interobserver Agreement Analysis. J. Cytol. (IF 1.3) Pub Date : 2022-08-17 Vaishali B Nagose,Meharbano M Kamal,Surbhi S Kathuria,Shraddha A Laddhad
Context The Indian Academy of Cytologists published Guidelines and categories for Reporting Serous Effusions (IACGRSE) in 2020 to improve consistency and reproducibility of fluid cytology reporting and to guide patient management. Aims To evaluate category-wise agreement while using IACGRSE 2020 categories. To analyze interobserver agreement among participants with different level of training and years
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Reclassification of Salivary Gland Aspirates Based on "The Milan System for Reporting Salivary Gland Cytology": A Five-Year Retrospective Study. J. Cytol. (IF 1.3) Pub Date : 2022-08-02 Saloni Pahwa,Poonam Panjwani,V Gnanapriya
Introduction The Milan System for reporting salivary gland cytopathology helps standardize reporting systems across institutions, improve communication between clinicians and pathologists and guide the clinical management of patients. Aims This study was undertaken to evaluate the utility of the Milan system classification in cytology reporting. Settings and Design The present study is a retrospective
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Correlation Between Fine-Needle Aspiration Cytology, Cell Block Cytology, and Histopathology in the Diagnosis of Thyroid Lesions. J. Cytol. (IF 1.3) Pub Date : 2022-07-30 Mohit Jambhulkar,Jasvinder K Bhatia,Samresh K Singh
Context Fine-needle aspiration cytology is considered the gold standard screening test in the evaluation of a thyroid nodule. We studied whether cell block cytology can be used in addition to conventional smears for the evaluation of tissue from fine-needle aspirations or fluid aspirations and also compared it with histopathological diagnosis. Aims The primary aim of this study was to know the utility
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Cytological Diagnosis of Malignant Mesothelioma: A Case Series. J. Cytol. (IF 1.3) Pub Date : 2022-07-30 Sakshi Dahiya,Meeta Singh,Shyama Jain,Bembem Khuraijam,Naman Suroya,Shramana Mandal
Background Mesotheliomas are neoplasms of the serosal lining of the body cavities. Diagnosis requires a multimodal approach of clinical findings, cytology, and histopathology with immunohistochemistry (IHC). The published sensitivity of cytology for diagnosing mesothelioma ranges from 30% to 75%. Aim and Objectives This study aimed to calculate the incidence of malignant mesothelioma (MM) at our institute
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FNA Unravelling the Mystery Behind the Cheek Mass to Pivot to a Diagnosis of a Primary Extracranial-Extraspinal-Meningioma with Intracranial Component. J. Cytol. (IF 1.3) Pub Date : 2022-07-30 Megha Murali,Ashitha Nanaiah,C P Arpitha,V Srinivas,Usha Kini
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How Accurately FNAC Reflects the Breast Papillary Lesions? J. Cytol. (IF 1.3) Pub Date : 2022-02-17 Gülistan Gümrükçü,Meryem Doğan,Nilüfer Gürsan,Barış Boylu,Erhan Ekren,Fügen Vardar Aker
Context Diagnosis of papillary lesions of the breast by fine needle aspiration cytology (FNAC) is problematic. For this reason, it is situated in the indeterminate zone in classification systems. Aims To ascertain the accuracy of cytological diagnosis of papillary lesions in distinguishing papillary lesions from non-papillary lesions and to determine whether papillomas can be reliably distinguished
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Evaluation of Use of RPMI Medium to Preserve Cell Morphology for Pleural/Peritoneal Fluid Cytology. J. Cytol. (IF 1.3) Pub Date : 2022-02-17 Usha Rani,Meeta Singh,Armaan Saith,Shayama L Jain,Anurag Aggarwal,Sunita Aggarwal
Introduction Cytologic evaluation is the best way to detect the presence of malignancy in body cavity fluids. Roswell Park Memorial Institute (RPMI) medium or RPMI 1640 is used in cell culture, tissue culture, and also to improve the cellularity and morphology of CSF cytology specimens. Objectives To determine whether RPMI medium can be used to preserve cell morphology in pleural/peritoneal effusion
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Intraoperative Sentinel Lymph Node Imprint Cytology Diagnosis in Breast Cancer Patients by General Surgical Pathologists: A Single-Institution Experience of 4327 Cases. J. Cytol. (IF 1.3) Pub Date : 2022-02-17 Yi-Chin Chang,Chi-Yuan Tzen
Context Sentinel lymph node (SLN) biopsy is the standard of care for breast cancer (BC) patient staging. The axillary node status can be evaluated by frozen section (FS) or imprint cytology (IC). Despite the major disadvantages of tissue loss and freezing artifact in FS, many pathologists consider SLN IC a more difficult task requiring special expertise and prefer FS to IC. Aims To conduct a large
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Analytical and Post Analytical Phase of an ISO 15189:2012 Certified Cytopathology Laboratory-A Five Year Institutional Experience. J. Cytol. (IF 1.3) Pub Date : 2022-02-03 Smita Chandra,Anuradha Kusum,Dushyant Singh Gaur,Harish Chandra
Objective Analytical and post analytical phase are integral part of total quality management system and include steps from submission of slides till reports are dispatched. The present study was conducted to analyze the analytical and post analytical phase of the ISO15189:2012 certified cytopathology laboratory. It was also intended to study the various errors which were encountered and steps taken
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Alveolar Rhabdomyosarcoma of the Parotid Region: A Cytopathological Diagnosis. J. Cytol. (IF 1.3) Pub Date : 2022-01-31 Pranjal Kalita,Biswajit Dey,Bifica Sofia Lyngdoh,Yookarin Khonglah,Devina Laishram
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Cytomorphological Categorization of Thyroid Lesions according to The Bethesda System for Reporting Thyroid Cytology and Correlation with their Histological Outcome: An Indian Oncology Centre Experience. J. Cytol. (IF 1.3) Pub Date : 2022-01-31 Meenakshi Kamboj,Anurag Mehta,Sunil Pasricha,Gurudutt Gupta,Anila Sharma,Garima Durga
Objective The objective of this study was to report the experience of an Indian premiere tertiary care oncology center in reporting fine needle aspiration cytology of thyroid lesions according to the Bethesda system of reporting thyroid cytopathology (TBSRTC) given by National Cancer Institute (NCI). These were then correlated with their histopathological outcome, analyzing the level of specificity
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A Comparative Study of Squash Smear Cytology Diagnosis and Radiological Diagnosis with Histopathology in Central Nervous System Lesions. J. Cytol. (IF 1.3) Pub Date : 2022-01-21 B N Kumarguru,G Santhipriya,S Kranthi Kumar,R Ramesh Kumar,A S Ramaswamy,P Janakiraman
Background Space occupying lesions (SOLs) of central nervous system (CNS) constitutes important cause of neurological morbidity and mortality. Squash cytology is technically a simple and rapid intraoperative diagnostic tool. Radiology is supportive of histopathological diagnosis. Objectives To enumerate the histopathological patterns of various central nervous system (CNS) lesions, to correlate cytopathological
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USG Guided Fine Needle Aspiration Cytology along with Immunocytochemistry to Diagnose Primary Malignant Mixed Mullerian Tumors: A Three-Year Study from a Tertiary Care Center. J. Cytol. (IF 1.3) Pub Date : 2022-01-21 Radhika Agarwal,Meeta Singh,Sneha Goswami,Shramana Mandal,Devender Verma,Nita Khurana,Shyama Jain,Nidhi Verma
Aims and Objectives To study the diagnostic utility of fine-needle aspiration cytology (FNAC) and immunocytochemistry in diagnosing primary malignant mixed Mullerian tumors (MMMT). Materials and Methods A 3-year retrospective study carried out in a tertiary care hospital, which included all the gynecological patients who underwent USG-guided FNAC of their abdominopelvic masses. Observations and Results
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Evaluation of hTERT Gene Expression and Chromosome 7 Copy Number Variation in Anal Squamous Intra-Epithelial Lesions: A Pilot Study. J. Cytol. (IF 1.3) Pub Date : 2022-01-21 Tanvi Arora,Neelam Wadhwa,Divya Aggarwal,Deepika Pandhi,Preeti Diwaker,Vinod K Arora
Background Akin to cervical squamous intra-epithelial neoplasia (CIN), anal squamous intra-epithelial lesion (a-SIL) is attributed to persistent infection with high-risk human papilloma virus infection. Amplification of human telomerase reverse transcriptase (hTERT) gene and aneuploidy are known to correlate with CIN evolution. It is plausible that the underlying genetic events in a-SIL are similar
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Association of micronuclear frequency with dysplasia and cytogenetic changes (p53 mutation and p16 expression) in oral potentially malignant disorders J. Cytol. (IF 1.3) Pub Date : 2022-01-01 Suvidha Tammewar,Rasika Gadkari
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Schwannoma of submandibular gland: A rare salivary gland neoplasm diagnosed by fine needle aspiration J. Cytol. (IF 1.3) Pub Date : 2022-01-01 TugbaTaskin Turkmenoglu,Sehbal Arslankoz
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Preliminary cytomorphologic diagnosis of hematolymphoid malignancies in effusions: A cyto-histo correlation with lessons on restraint J. Cytol. (IF 1.3) Pub Date : 2022-01-01 Debasis Gochhait,BidishK Patel,Sreerekha Jinkala,Vidhyalakshmi Rangarajan,Narasimhapriyan Kannan,S Durgadevi,Neelaiah Siddaraju
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Exfoliation of uterine leiomyosarcoma in cervical scrape smear with histopathological correlation J. Cytol. (IF 1.3) Pub Date : 2022-01-01 Priyanka Uttam,AshishK Gupta,Nighat Hussain,Nidhi Rai
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Strength and weaknesses of application of international academy of cytology yokohama system for reporting breast fine-needle aspiration cytopathology J. Cytol. (IF 1.3) Pub Date : 2022-01-01 Preeti Agarwal,Isha Makker,Shivanjali Raghuvanshi,Madhu Kumar,Mala Sagar
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Xanthogranulomatous cholecystitis with coexisting carcinoma- A diagnostic pitfall in cytology J. Cytol. (IF 1.3) Pub Date : 2022-01-01 Anupama Arya,Shaily Goyal,Dilip Kumar,Poonam Das
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Cytological diagnosis of chondromyxoid fibroma J. Cytol. (IF 1.3) Pub Date : 2022-01-01 PV Nishath,Purushotham Reddy,SM Choukimath,AA Hosangadi
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Application of the Indian academy of cytologists recommendations for reporting serous fluid cytopathology in routine reporting of ascitic fluid specimen and assessment of the risk of malignancy J. Cytol. (IF 1.3) Pub Date : 2022-01-01 AmitKumar Adhya,Shilpy Jha,Madhusmita Sethy