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High heart rate variability buffers the effect of attachment insecurity on sleep quality. Psychosom. Med. (IF 3.3) Pub Date : 2024-03-04 Jensine Paoletti, Daniel L Argueta, E Lydia Wu-Chung, Michelle A Chen, Ryan L Brown, Angie S LeRoy, Kyle W Murdock, Julian F Thayer, Christopher P Fagundes
Sleep quality is an important health-protective factor. Psychosocial factors, including attachment orientation, may be valuable for understanding who is at risk of poor sleep quality and associated adverse health outcomes. High attachment anxiety is reliably associated with adverse health outcomes, while high attachment avoidance is associated with adverse health outcomes when co-occurring with poor
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Dynamic Associations Among Sleep, Emotion Dysregulation, and Desire to Live in a Perinatal Sample. Psychosom. Med. (IF 3.3) Pub Date : 2024-03-04 Parisa R Kaliush, Jonathan E Butner, Paula G Williams, Elisabeth Conradt, Sheila E Crowell
The present study prospectively examined dynamic associations among sleep, emotion dysregulation, and desire to live during the perinatal transition, as it was theorized that these factors may contribute to the emergence of postpartum suicide risk.
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Discrimination and Cardiovascular Health in Black Americans: Exploring Inflammation as a Mechanism and Perceived Control as a Protective Factor. Psychosom. Med. (IF 3.3) Pub Date : 2024-03-04 Carrington C Merritt, Keely A Muscatell
Inflammation may be an integral physiological mechanism through which discrimination impacts cardiovascular health and contributes to racial health disparities. Limited research has examined psychosocial factors that protect against the negative effects of discrimination on inflammation. Perceived control is a promising possible protective factor, given that it has been shown to moderate the relationship
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Objective and Subjective Intraindividual Variability in Sleep: Predisposing Factors and Health Consequences. Psychosom. Med. (IF 3.3) Pub Date : 2024-03-04 Chenlu Gao, Michael K Scullin
We investigated the factors that predispose or precipitate greater intra-individual variability (IIV) in sleep. We further examined the potential consequences of IIV to overall sleep quality and health outcomes, including whether these relationships were found in both self-reported and actigraphy-measured sleep IIV.
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Sleep Disturbance as a Mediator of Lung Cancer Stigma on Psychological Distress and Physical Symptom Burden. Psychosom. Med. (IF 3.3) Pub Date : 2024-02-27 Timothy J Williamson, Edward B Garon, Michael R Irwin, Alyssa K Choi, Jonathan W Goldman, Annette L Stanton
This study tested sleep disturbance as a mediator through which stigma and discrimination predict psychological distress and physical symptom burden in adults with lung cancer.
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10-year Stability of an Insomnia Sleeper Phenotype and Its Association with Chronic Conditions. Psychosom. Med. (IF 3.3) Pub Date : 2024-02-16 Soomi Lee, Claire E Smith, Meredith L Wallace, Orfeu M Buxton, David M Almeida, Sanjay R Patel, Ross Andel
To identify distinct sleep health phenotypes in adults, examine transitions in sleep health phenotypes over time and subsequently relate these to the risk of chronic conditions.
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Childhood maltreatment and leukocyte telomere length: Cardiac vagal activity influences the relation in older adults. Psychosom. Med. (IF 3.3) Pub Date : 2024-02-12 Alexandra Connor, Alain Deschamps, Lambert Busque, Jean-Claude Tardif, Vincent Bourgoin, Marie-Pierre Dubé, David Busseuil, Bianca D'Antono
Childhood maltreatment is associated with shorter leukocyte telomere length (LTL). However, the influence of cardiac vagal control on this relation is unknown. We examined whether cardiac vagal control at rest and in response to stress moderates or cross-sectionally mediates the relationship between childhood maltreatment and LTL.
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Associations between Structural Stigma and Allostatic Load among Sexual Minorities: Results from a Population-Based Study. Psychosom. Med. (IF 3.3) Pub Date : 2024-02-12 Robert-Paul Juster, Caroline Rutherford, Katherine Keyes, Mark L Hatzenbuehler
Structural forms of stigma and discrimination are associated with adverse health outcomes across numerous stigmatized groups, including lesbian, gay, and bisexual (LGB) individuals. Yet, the biological consequences of structural stigma among LGB populations are understudied. To begin to address this gap, we assessed associations between indicators of structural stigma (i.e., state-level policies) targeting
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Fulfilled mind, healthy gut? Relationships of eudaimonic psychological well-being with the gut microbiome in postmenopausal women. Psychosom. Med. (IF 3.3) Pub Date : 2024-01-15 Anne-Josee Guimond, Shanlin Ke, Shelley S Tworoger, Tianyi Huang, Andrew T Chan, Laura D Kubzansky, Yang-Yu Liu
Eudaimonic facets of psychological well-being (PWB), like purpose in life and sense of mastery, are associated with healthy aging. Variation in the gut microbiome may be one pathway by which mental health influences age-related health outcomes. Yet, associations between eudaimonic PWB and the gut microbiome are understudied. We examined whether purpose in life and sense of mastery, separately, were
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Cumulative stress across the lifecourse and biological aging in adulthood. Psychosom. Med. (IF 3.3) Pub Date : 2024-01-11 Shakira F Suglia Ms, Elizabeth S Clausing, Rachel C Shelton, Karen Conneely, Diddier Prada-Ortega, Immaculata DeVivo, Pam Factor-Litvak, Piera Cirillo, Andrea A Baccarelli, Barbara Cohn, Bruce G Link
Psychosocial stressors have been linked with accelerated biological aging in adults; however, few studies have examined stressors across the lifecourse in relation to biological aging.
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Dyadic Investigation of Posttraumatic Stress Symptoms and Daily Sleep Health in Patients with Cancer and their Caregivers. Psychosom. Med. (IF 3.3) Pub Date : 2024-01-11 Thomas C Tsai, Hannah-Rose Mitchell, Jamie Zeitzer, Amanda Ting, Jean-Philippe Laurenceau, David Spiegel, Youngmee Kim
Cancer can be a traumatic experience affecting multidimensional aspects of sleep among patients and caregivers. This study examined the differential associations of cancer-related post-traumatic stress symptoms (PTSS) with various sleep markers in this population.
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Pre-Existing Psychiatric Conditions as Risk Factors for Diagnosed Long COVID-19 Syndrome within Aggregated Electronic Health Record Data. Psychosom. Med. (IF 3.3) Pub Date : 2024-01-09 Lukas Bobak, Ian Dorney, Alexsandra Kovacevich, Brian Barnett, David C Kaelber
To investigate the frequency of long COVID diagnosis among patients infected with SARS-CoV-2 with pre-existing psychiatric conditions versus those without pre-existing psychiatric conditions.
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Optimism and Sleep in Aging Women: Bidirectional Relationships. Psychosom. Med. (IF 3.3) Pub Date : 2024-01-09 Addison D Monroe, Stephanie T Judge, Chelsea L Bass, Leslie J Crofford, Suzanne C Segerstrom
Sleep quality and duration are important for biological restoration and promotion of psychological well-being. Optimism may facilitate or result from sufficient sleep, but questions remain as to directionality. The present study tested how optimism is associated with levels of and variability in sleep quantity and quality in a longitudinal burst design.
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Association of 20-year longitudinal depressive symptoms with left ventricular geometry outcomes in the Coronary Artery Risk Development in Young Adults study: a role for androgens? Psychosom. Med. (IF 3.3) Pub Date : 2024-01-09 Laura A Colangelo, Allison J Carroll, Amanda M Perak, Samuel S Gidding, Joao A C Lima, Donald M Lloyd-Jones
Depression is a risk factor for coronary heart disease (CHD) and left ventricular hypertrophy (LVH) is a potent predictor of CHD events. Whether depression is associated with LVH has received limited investigation. This study assessed cross-sectional and 20-year longitudinal associations of depressive symptoms with LVH outcomes after accounting for important known confounders.
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Perceived Control and Inflammation: Mediating and Moderating Effects in the Relationship Between Cumulative Trauma and Depression. Psychosom. Med. (IF 3.3) Pub Date : 2024-01-09 Zachary E Magin, Crystal L Park, Jeffrey D Burke, Frank J Infurna
The effects of trauma exposure on depression risk and severity are well-established, but psychosocial and biological factors that impact or explain those relationships remain poorly understood. This study examined the moderating and mediating effects of perceived control and inflammation in the relationship between trauma and depression.
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Social isolation, physical activity, and subsequent changes in cognition among middle- and older-aged adults: Results from the Canadian Longitudinal Study on Aging. Psychosom. Med. (IF 3.3) Pub Date : 2024-01-08 Shawna Hopper, Andrew V Wister, Theodore D Cosco, John R Best
The objectives of this study are to: 1) evaluate associations between social isolation and change in cognition over a three-year period, and 2) evaluate whether physical activity mediates the association between social isolation and cognition change.
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The severity of depressive symptoms as an independent predictor of Sustained Virological Response during treatment for hepatitis C with pegylated interferon-α2a and oral ribavirin. Psychosom. Med. (IF 3.3) Pub Date : 2024-01-08 Tomasz Pawłowski, Marek Radkowski, Karol Perlejewski, Tomasz Laskus, Krzysztof Małyszczak
Sustained virologic response (SVR) is the best indicator of successful therapy for hepatitis C virus (HCV) infection. Patients with chronic HCV infection treated with pegylated interferon-alfa and ribavirin (PEG-IFN-α /RBV) can achieve SVR 56% of the time.Objectives. To evaluate baseline predictors of SVR in patients treated with PEG-IFN-α /RBV for HCV chronic infection.
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Glucocorticoid and adrenergic receptor distribution across human organs and tissues: a map for stress transduction. Psychosom. Med. (IF 3.3) Pub Date : 2024-01-08 Sophia Basarrate, Anna S Monzel, Janell Smith, Anna Marsland, Caroline Trumpff, Martin Picard
Psychosocial stress is transduced into disease risk through energy-dependent release of hormones from the HPA and SAM axes. The levels of glucocorticoid and adrenergic hormones, together with the sensitivity of tissues to their signaling, define stress responses. To understand existing pathways responsible for the psychobiological transduction of stressful experiences, we provide a quantitative whole-body
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Increased Cardiometabolic Risk in Healthy Young Adults with Early Life Stress. Psychosom. Med. (IF 3.3) Pub Date : 2023-12-29 Meghan J Kulak, William Lewis-de Los Angeles, Teresa E Daniels, Karen J Mathis, Asi P Gobin, Laura E Laumann, Quincy Beck, Audrey R Tyrka
To evaluate the relationship between early life stress (ELS) and metabolic risk in healthy young adults and assess the role of health behaviors.
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Neighborhood Perceptions are Associated with Intrinsic Amygdala Activity and Resting-State Connectivity with Salience Network Nodes Among Older Adults. Psychosom. Med. (IF 3.3) Pub Date : 2023-12-28 Lola R Ortiz-Whittingham, Liang Zhan, Erika N Ortiz-Chaparro, Yvonne Baumer, Shannon Zenk, Melissa Lamar, Tiffany M Powell-Wiley
Neighborhood perceptions are associated with physical and mental health outcomes; however, the biological associates of this relationship remain to be fully understood. Here, we evaluate the relationship between neighborhood perceptions and amygdala activity and connectivity with salience network (i.e. insula, anterior cingulate, thalamus) nodes.
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Association of diabetes mellitus in pregnancy and perinatal depression. Psychosom. Med. (IF 3.3) Pub Date : 2023-11-22 Richelle D Björvang, Iliana Liakea, Beatrice Carpentsier, Zoltan Kozinszky, Alkistis Skalkidou, Emma Fransson
Diabetes is frequently linked with depression, and both conditions are common complications during pregnancy. However, research findings exploring the relationship between Diabetes Mellitus in Pregnancy (DMP) and Perinatal Depression (PND) have been inconsistent. Thus, this study seeks to examine the association between DMP and PND in a prospective population-based cohort.
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Association between global sleep quality and coronary microvascular function in male physicians with occupational burnout. Psychosom. Med. (IF 3.3) Pub Date : 2023-11-17 Roland von Känel, Mary Princip, Sarah A Holzgang, Alexia Rossi, Andreas A Giannopoulos, Ronny R Buechel, Claudia Zuccarella-Hackl, Aju P Pazhenkottil
Occupational burnout has been associated with an increased risk of coronary heart disease, although the mechanisms involved are elusive. We investigated whether poor global sleep quality is associated with impaired coronary microvascular function in male physicians, a professional group at increased risk for burnout.
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How Loneliness Gets Under the Skin: Inflammation Mediates the Relationship between Loneliness and Gait Speed. Psychosom. Med. (IF 3.3) Pub Date : 2023-11-17 Rebecca K MacAulay, Holly R Timblin, Morgan D Tallman
Loneliness is linked to interleukin-6 (IL-6), a marker of systemic inflammation, which chronically has deleterious effects on physical and mental health across the adult life span. This study investigated cross-sectional relationships among loneliness, IL-6, demographics, multimorbidity, depression, obesity, friendship quantity, and slowed gait.
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Mindfulness-Based Stress Reduction reduces pro-inflammatory gene regulation but not systemic inflammation among older adults: A randomized controlled trial. Psychosom. Med. (IF 3.3) Pub Date : 2023-11-17 Emily K Lindsay, Anna L Marsland, Steven W Cole, Janine M Dutcher, Carol M Greco, Aidan G C Wright, Kirk Warren Brown, J David Creswell
Aging is associated with increased pro-inflammatory gene expression and systemic inflammation, and psychosocial stress may accelerate these changes. Mindfulness interventions show promise for reducing psychosocial stress and extending healthspan. Inflammatory pathways may play a role. In a sample of lonely older adults, we tested whether mindfulness training reduces proinflammatory gene expression
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Lifespan socioeconomic context is associated with cytomegalovirus and late-differentiated CD8+ T and NK cells: Initial results in older adults. Psychosom. Med. (IF 3.3) Pub Date : 2023-11-16 Rebecca G Reed, Abby R Hillmann, Steven R Presnell, Ahmad Al-Attar, Charles T Lutz, Suzanne C Segerstrom
Lower socioeconomic status (SES) can accelerate immune aging; however, it is unknown whether and how lifespan socioeconomic context (SEC) -the relative wealth and quality of the communities an individual lives in across their lifespan- impacts immune aging. We examined the effects of childhood and adulthood SEC on late-differentiated immune cells and investigated the mediating and moderating role of
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Self-acceptance and Purpose in life are Mechanisms Linking Adverse Childhood Experiences to Mortality Risk. Psychosom. Med. (IF 3.3) Pub Date : 2023-11-16 Páraic S O'Súilleabháin, Sinéad D'Arcy-Bewick, Milou Fredrix, Máire McGeehan, Emma Kirwan, Meredith Willard, Amanda A Sesker, Angelina R Sutin, Nicholas A Turiano
Adverse childhood experiences (ACEs) are associated with increased risk of premature mortality, but it is not clear why. Individuals with ACEs tend to have lower self-acceptance and purpose in life, which may be pathways between ACEs and risk of premature mortality. As such, we tested whether purpose and self-acceptance are mechanisms that link ACEs to mortality risk.
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The impact of mindfulness-based interventions on objective physiological measures of autonomic function for individuals with medical conditions: a review of the evidence. Psychosom. Med. (IF 3.3) Pub Date : 2023-11-14 Rachel Churchill, Brenda Swartz, Anneka Johnston-Dumerauf, Angelos Halaris
Autonomic dysregulation is common in many medical conditions and can have a widespread, negative impact on multiple bodily systems, leading to poorer health outcomes. Thus, addressing autonomic dysregulation as part of a comprehensive treatment plan is important. The goal of this paper was to gain a better understanding of the physiological benefits of a mindfulness-based intervention (MBI) for a population
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Treatment effects on psychophysiological stress responses in youth with obesity. Psychosom. Med. (IF 3.3) Pub Date : 2023-11-10 Annelies Van Royen, Ine Verbiest, Heleen Goemaere, Taaike Debeuf, Nathalie Michels, Sandra Verbeken, Caroline Braet
Stress plays a central role in obesity development but research on treatment options to tackle elevated stress levels in youth with obesity is scarce. The present study examined the impact of the Multidisciplinary Obesity Treatment (MOT; lifestyle intervention including physical exercise, healthy meals, and Cognitive Behavioral Techniques) on physiological stress parameters in youth with obesity and
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Effects of daily posttraumatic stress disorder symptoms on heart rate variability. Psychosom. Med. (IF 3.3) Pub Date : 2023-11-10 Danica C Slavish, Camilo J Ruggero, Keke Schuler, Joseph E Schwartz, Benjamin Luft, Roman Kotov
Posttraumatic stress disorder (PTSD) is common, debilitating, and associated with increased risk for health problems, including cardiovascular disease (CVD). PTSD is related to poor autonomic function indicated by reduced heart rate variability (HRV). Yet very little work has tested the timescale or direction of these effects, given most evidence comes from cross-sectional studies. Documentation of
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Financial Hardship and Age-Related Decrements in Kidney Function among Black and White Adults in the Midlife in the United States (MIDUS) Study. Psychosom. Med. (IF 3.3) Pub Date : 2023-11-10 Agus Surachman, Meera Harhay, Alexis R Santos, Jonathan Daw, Lacy M Alexander, David M Almeida, Christopher L Coe
This analysis examined if financial hardship was associated with age-related decrements in kidney function using a material-psychosocial-behavioral framework. We also tested if this association was mediated by comorbidity of cardiometabolic risk factors (obesity, elevated blood pressure, and insulin resistance).
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Depression, Inflammation, and the Moderating Role of Metformin: Results from the Midlife in the United States (MIDUS) Study and Sacramento Area Latino Study on Aging (SALSA). Psychosom. Med. (IF 3.3) Pub Date : 2023-10-24 Sumaiyah U Syed, Jared I Cortez, Stephanie J Wilson
Depression can promote inflammation and accelerate aging. Metformin, a widely prescribed antidiabetic, has shown promising preclinical evidence of aging-related health benefits, including decreased inflammation. The current study examined whether metformin usage buffers the association between depressive symptoms and inflammatory markers in two large samples of middle-aged and older, primarily white
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Chronic social and psychological stress impact select neuropathologies in the PS19 mouse model of tauopathy. Psychosom. Med. (IF 3.3) Pub Date : 2023-10-03 Carey E Lyons, Sara I Graves, Maria Razzoli, Karthik Jeganathan, Rachel P Mansk, Seth McGonigle, Nivedita Sabarinathan, Jan M van Deursen, Darren J Baker, Alessandro Bartolomucci
Despite advances toward understanding the etiology of Alzheimer's disease (AD), it remains unclear which aspects of this disease are affected by environmental factors. Chronic life stress increases risk for aging-related diseases including AD. The impact of stress on tauopathies remains understudied. We examined the effects of stress elicited by social (chronic subordination stress, CSS) or psychological/physical
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All Stressors Aren't Equal: The Salience of Racial Discrimination and Appraisal for Blood Pressure in African American Women. Psychosom. Med. (IF 3.3) Pub Date : 2023-09-29 Alexis Reeves, Eli K Michaels, Marilyn D Thomas, Uche Okoye, Melisa M Price, Rebecca E Hasson, David H Chae, Amani M Allen
Psychosocial stress is a major predictor of chronic disease among African American (AA) women. Stress is a process involving exposure, appraisal of threat, coping, and psychobiologic adaptation. However, many studies focus on the frequency of stress events and/or coping; few explicitly study stress events and their appraisals. AA women experience high levels of racial discrimination, a well-known form
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Bidirectional associations between pain and perceived stress among veterans: Depressive disorder as a predisposing factor. Psychosom. Med. (IF 3.3) Pub Date : 2023-09-29 Shaddy K Saba, Jordan P Davis, John J Prindle, Esther Howe, Denise D Tran, John Bunyi, Justin F Hummer, Carl Andrew Castro, Eric R Pedersen
Military veterans who were injured in combat very often report pain along with co-occurring perceived stress and pre-existing depressive disorder. The systems model of pain is a theoretical model suggesting pain and perceived stress are bidirectionally associated at the within-person level, and associations are heightened among those with depressive disorder. However, the systems model of pain has
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Circulating cell-free mitochondrial DNA (cf-mtDNA) and depressive symptoms among low-active adults who smoke. Psychosom. Med. (IF 3.3) Pub Date : 2023-09-29 Teresa E Daniels, Emily K Zitkovsky, Laura E Laumann, Zachary J Kunicki, Destiny J Price, Abigail L Peterson, Phyllis A Dennery, Hung-Teh Kao, Stephanie H Parade, Lawrence H Price, Ana M Abrantes, Audrey R Tyrka
Mitochondrial dysfunction is implicated in the pathophysiology of psychiatric disorders. Levels of circulating cell-free mitochondrial DNA (cf-mtDNA) are observed to be altered in depression. However, the few studies that have measured cf-mtDNA in depression have reported conflicting findings. This study examined cf-mtDNA and depressive symptoms in low- active adults who smoke.
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Associations of Germline Genetic Variants with Depression and Fatigue among Hematologic Cancer Patients Treated with Allogeneic Hematopoietic Cell Transplantation. Psychosom. Med. (IF 3.3) Pub Date : 2023-09-06 Aasha I Hoogland, Brian D Gonzalez, Jong Y Park, Brent J Small, Steven K Sutton, Joseph A Pidala, Kristen S Smith, Julienne E Bower, Paul B Jacobsen, Heather S L Jim
Depression and fatigue are common among cancer patients and are associated with germline genetic variation. The goal of this pilot study was to examine genetic associations with depression and fatigue in the year after allogeneic HCT.
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Association of Self-Reported Autonomic Symptoms with Sensor-Based Physiological Measures. Psychosom. Med. (IF 3.3) Pub Date : 2023-09-06 Jacek Kolacz, Xiwei Chen, Evan J Nix, Olivia K Roath, Logan G Holmes, Clarissa Tokash, Stephen W Porges, Gregory F Lewis
Autonomic regulation of organ and tissues may give rise to disruptions of typical functions. The Body Perception Questionnaire Short Form (BPQ-SF) includes items that were developed to assess autonomic symptoms in daily life. This pair of studies aimed to establish previously unexplored psychometric properties of the BPQ-SF autonomic symptoms scale, develop normative values for clinical and research
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Older Adults' Social Profiles and Links to Functional and Biological Aging in the United States and Mexico. Psychosom. Med. (IF 3.3) Pub Date : 2023-09-06 Stephanie J Wilson, Christina M Marini
Social stress-loneliness, isolation, and low relationship quality-increase risks for aging-related diseases. However, the ways in which they intersect to undermine healthy aging remain poorly understood. We utilized latent class analysis to identify groups of older adults based on their social stress in both the United States and Mexico. Thereafter, we examined their cross-sectional associations with
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Association between estradiol and human aggression: a systematic review and meta-analysis. Psychosom. Med. (IF 3.3) Pub Date : 2023-08-24 Yalan Wang, Haifang Wang, Jianzheng Cai, Weixia Yu, Yingying Zhang, Ying Zhang, Zhaofang Tang
Although several studies have examined the association between estradiol and human aggression, a consistent understanding of their correlation has yet to be established. This study aimed to investigate this relationship comprehensively.
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Is positive communication sufficient to modulate procedural pain and anxiety in the emergency room? A randomized controlled trial. Psychosom. Med. (IF 3.3) Pub Date : 2023-08-24 Chantal Berna, Anne Favre-Bulle, Adelaïde Bonzon, Nathan Gross, Ariane Gonthier, Hélène Gerhard-Donnet, Patrick Taffé, Olivier Hugli
Research suggests that therapeutic communication could enhance patient comfort during medical procedures. Few studies have been conducted in clinical settings, with adequate blinding. Our hypothesis was that a positive message could lead to analgesia and anxiolysis, and that this effect would be enhanced by an empathetic interaction with the nurse performing the procedure, compared to an audio-taped
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Respiratory Interoception and Pathological Illness Anxiety: Disentangling Bias. Psychosom. Med. (IF 3.3) Pub Date : 2023-08-21 Timo Slotta, Carolin Wolters, Zeynep Marx, Michael Witthöft, Alexander L Gerlach, Anna Pohl
Biased interoception decoupled from physiology might be relevant in the etiology of pathological illness anxiety. Empirical evidence for interoceptive deviations in illness anxiety is scarce but potentially informative to optimize treatments. We hypothesized that persons with pathological illness anxiety differ fundamentally in the classification of bodily sensations from those without pathological
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Parental preconception posttraumatic stress symptoms and maternal prenatal inflammation prospectively predict shorter telomere length in children. Psychosom. Med. (IF 3.3) Pub Date : 2023-08-21 Gabrielle R Rinne, Judith E Carroll, Christine M Guardino, Madeleine U Shalowitz, Sharon Landesman Ramey, Christine Dunkel Schetter
Parental trauma exposure and trauma-related distress can increase risk for adverse health outcomes in offspring, but the pathways implicated in intergenerational transmission are not fully explicated. Accelerated biological aging may be one mechanism underlying less favorable health in trauma-exposed individuals and their offspring. This study examines associations of preconception maternal and paternal
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Short sleep and insomnia are associated with accelerated epigenetic age. Psychosom. Med. (IF 3.3) Pub Date : 2023-08-21 Cynthia D J Kusters, Eric T Klopack, Eileen M Crimmins, Teresa E Seeman, Steve Cole, Judith E Carroll
Short sleep and insomnia are each associated with greater risk for age-related disease, which suggests that insufficient sleep may accelerate biological aging. We examine whether short sleep and insomnia alone or together relate to epigenetic age among older adults.
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Lower Body Mass Index at Baseline is Related to Steeper Cognitive Decline in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Cohort. Psychosom. Med. (IF 3.3) Pub Date : 2023-08-21 Andreana P Haley, Alexandra L Clark, Audrey Duarte
Midlife obesity is a risk factor for dementia, while obesity in older age may be protective of cognition, a phenomenon known as the "obesity paradox." The mechanisms underlying this phenomenon and the relationship between Body Mass Index (BMI) and cognitive function over time remain unclear.
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Effectiveness of Human-supported and Self-help eHealth Lifestyle Interventions for Patients with Cardiometabolic Risk Factors: A Meta-analysis. Psychosom. Med. (IF 3.3) Pub Date : 2023-08-07 Talia R Cohen Rodrigues, Linda D Breeman, Asena Kinik, Thomas Reijnders, Elise Dusseldorp, Veronica R Janssen, Roderik A Kraaijenhagen, Douwe E Atsma, Andrea W M Evers
eHealth is a useful tool to deliver lifestyle interventions for patients with cardiometabolic diseases. However, there are inconsistent findings about whether these eHealth interventions should be supported by a human professional, or whether self-help interventions are equally effective.
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Intimate Partner Violence and Inflammaging: Conflict Tactics Predict Inflammation Among Middle-Aged and Older Adults. Psychosom. Med. (IF 3.3) Pub Date : 2023-08-07 Annelise A Madison, Stephanie J Wilson, M Rosie Shrout, William B Malarkey, Janice K Kiecolt-Glaser
In long-term relationships, conflict is inevitable, but physical and psychological aggression is not. Intimate partner violence (IPV) is a known risk factor for age-related disease onset, and inflammation likely links the two. This study explores relationships between frequency of constructive (i.e., negotiation) and destructive (i.e., aggression) conflict tactics with inflammation in both younger
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DNA methylation signatures of functional somatic syndromes: Systematic review. Psychosom. Med. (IF 3.3) Pub Date : 2023-08-03 Susanne Fischer, Maria Kleinstäuber, Laura M Fiori, Gustavo Turecki, Julia Wagner, Roland von Känel
Functional somatic syndromes (FSS) are highly prevalent across all levels of healthcare. The fact that they are characterised by medically unexplained symptoms, such as fatigue and pain, raises the important question of their underlying pathophysiology. Psychosocial stress represents a significant factor in the development of FSS and can induce long-term modifications at the epigenetic level. The aim
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Social Regulation of the Neural Threat Response Predicts Subsequent Markers of Physical Health. Psychosom. Med. (IF 3.3) Pub Date : 2023-08-03 Jingrun Lin, Nauder Namaky, Meghan Costello, Bert N Uchino, Joseph P Allen, James A Coan
Social support has been linked to a vast range of beneficial health outcomes. However, the physiological mechanisms of social support are not well characterized. Drawing on fMRI and health-related outcome data, this study aimed to understand how neural measures of "yielding" - the reduction of brain activity during social support - moderates the link between social support and health.
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Technological Innovations in Biobehavioral and Psychosomatic Medicine. Psychosom. Med. (IF 3.3) Pub Date : 2023-07-31 Mirela Habibović, Bruce Rollman
The role of technological innovations in healthcare has increased over the past years and will continue to improve the diagnosis, monitoring and treatment of various physical and mental disorders. In biobehavioral and psychosomatic medicine. the use of technology has also increased both in research and clinical contexts. The articles in the current special issue of Psychosomatic Medicine focus on technological
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Validation of Photoplethysmography Using a Mobile Phone Application for the Assessment of Heart Rate Variability in the Context of Heart Rate Variability-Biofeedback. Psychosom. Med. (IF 3.3) Pub Date : 2023-07-25 Willeke van Dijk, Anja C Huizink, Mirjam Oosterman, Imke L J Lemmers-Jansen, Wieke de Vente
Heart rate variability-biofeedback (HRV-BF) is an effective intervention to reduce stress and anxiety and requires accurate measures of real-time HRV. HRV can be measured through photoplethysmography (PPG) using the camera of a mobile phone. No studies have directly compared HRV-BF supported through PPG against classical electrocardiogram (ECG). The current study aimed to validate PPG HRV measurements
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Differential Associations of Childhood Abuse and Neglect with Adult Autonomic Regulation and Mood-Related Pathology. Psychosom. Med. (IF 3.3) Pub Date : 2023-07-25 Sarah K Stevens, DeWayne P Williams, Julian F Thayer, Alyson K Zalta
This study assessed whether different types of childhood maltreatment (i.e., abuse vs. neglect) had differential relationships with heart rate variability (HRV) and baroreflex sensitivity (BRS). Additionally, this study tested the indirect effect of maltreatment subtypes on adult mood-related psychopathology via HRV, and whether these relationships differed in those with HRV above and below established
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Racial discrimination and hypothalamic-pituitary-adrenal axis dysregulation in adolescents with overweight and obesity: does context matter? Psychosom. Med. (IF 3.3) Pub Date : 2023-07-13 Jonel E Emlaw, Tiwaloluwa A Ajibewa, Claudia M Toledo-Corral, Rebecca E Hasson
The role of context, for which a discriminatory event occurs, on cortisol dysregulation is unclear in adolescents at higher risk for chronic disease. The purpose of this study was to perform a cross-sectional analysis examining the association between racial discrimination context (peer, educational, institutional, and cumulative) and diurnal cortisol patterning in adolescents with overweight and obesity
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Racial and educational disparities in cumulative exposure to hardships of the 2008 Great Recession and inflammation. Psychosom. Med. (IF 3.3) Pub Date : 2023-07-13 Julie A Kirsch, Christopher Coe, Carol D Ryff
This cross-sectional analysis examined self-reported economic hardships of the 2008 Great Recession, race/ethnicity, educational attainment, and psychological well-being (PWB) as predictors of systemic inflammatory physiology at midlife. We also tested for differential vulnerability in the relationship between recession hardship and inflammatory physiology by race/ethnicity, education, and PWB.
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Postpartum Insomnia and Poor Sleep Quality are Longitudinally Predictive of Postpartum Mood Symptoms. Psychosom. Med. (IF 3.3) Pub Date : 2023-07-13 Michele L Okun, Andrew Lac
Insomnia and poor sleep quality are frequently reported by perinatal women. Both are noted to increase risk for postpartum depression, with less known about their association with postpartum anxiety. The study sought to assess whether perinatal sleep disturbances predicted depression and anxiety symptomatology across each month of the first 6 months postpartum in women with a history of depression
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Longitudinal Patterns of Engagement and Clinical Outcomes: Results from a Therapist-Supported Digital Mental Health Intervention. Psychosom. Med. (IF 3.3) Pub Date : 2023-07-07 Kirstin Aschbacher, Luisa M Rivera, Silvan Hornstein, Benjamin W Nelson, Valerie L Forman-Hoffman, Nicholas C Peiper
Digital mental health interventions (DMHI) are an effective treatment modality for common mental disorders like depression and anxiety; however, the role of intervention engagement as a longitudinal "dosing" factor is poorly understood in relation to clinical outcomes.
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Smartphone Photoplethysmography Pulse Rate Covaries with Stress and Anxiety During a Digital Acute Social Stressor. Psychosom. Med. (IF 3.3) Pub Date : 2023-07-07 Benjamin W Nelson, Helen M K Harvie, Barbie Jain, Erik L Knight, Leslie E Roos, Ryan J Giuliano
Heart rate is a transdiagnostic correlate of affective states and the stress diathesis model of health. While most psychophysiological research has been conducted in laboratory environments, recent technological advances have provided the opportunity to index pulse rate dynamics in real world environments with commercially available mobile health (mHealth) and wearable photoplethysmography (PPG) sensors
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Spousal synchrony in allostatic load among older couples in the Health and Retirement Study. Psychosom. Med. (IF 3.3) Pub Date : 2023-07-07 Yan-Liang Yu, Robert-Paul Juster
Using national data from the Health and Retirement Study, this study examined interpartner associations of allostatic load (AL) among 2,338 different-sex couples (N = 4,676 individuals) over a four-year period among older American couples from a dyadic approach.
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Personal and interpersonal factors moderate the relation between human-made trauma and hypertension: a path analysis approach. Psychosom. Med. (IF 3.3) Pub Date : 2023-06-27 Achille M Bapolisi, Pierre Maurage, Coralie M G Georges, Géraldine Petit, Mitterrand Balola, Cirhuza J Cikomola, Bernard Rime, Pierre Philippot, Alexandre Persu, Philippe de Timary
While the link between trauma, post-traumatic stress disorder (PTSD) and hypertension is established, its underlying mechanisms remain underexplored.
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Recovery sleep following sleep restriction is insufficient to return elevated daytime heart rate and systolic blood pressure to baseline levels. Psychosom. Med. (IF 3.3) Pub Date : 2023-06-27 David A Reichenberger, Kelly M Ness, Stephen M Strayer, Gina Marie Mathew, Margeaux M Schade, Orfeu M Buxton, Anne-Marie Chang
Sleep restriction alters daytime cardiac activity, including elevating heart rate (HR) and blood pressure (BP). There is minimal research on the cumulative effects of sleep loss and the response after subsequent recovery sleep on HR and BP. This study examined patterns of HR and BP across baseline, sleep restriction, and recovery conditions using multiple daytime cardiac measurements.
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Acute and chronic stress associations with blood pressure: An ecological momentary assessment study on an app-based platform. Psychosom. Med. (IF 3.3) Pub Date : 2023-06-27 Hio Wa Mak, Amie M Gordon, Aric A Prather, Elissa S Epel, Wendy Berry Mendes
This study examines the within- and between-person associations of acute and chronic stress with blood pressure (BP) and heart rate (HR) using an app-based research platform.