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Can bumetanide be a miraculous medicine for autism spectrum disorder: Meta-analysis evidence from randomized controlled trials Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-03-09 Hong-Li Xiao, Han Zhu, Jia-Qi Jing, Si-Jia Jia, Su-Hong Yu, Chang-Jiang Yang
The efficacy of bumetanide on autism spectrum disorders (ASD) has been extensively studied, but the results remain inconclusive, necessitating a critical examination to determine its therapeutic role. Therefore, this study conducted a meta-analysis of bumetanide treatments for ASD to explore its efficacy and identify subpopulation that responded positively. A systematic search was conducted on PubMed
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A qualitative investigation on the resilience of parents of children with autism spectrum disorder in Macau Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-03-02 Kelly Ka Lai Lam, Chong Nga Chan, Louise Ho Wong, Yanping He, Xiuyun Lin, Peilian Chi
Parenting a child with autism spectrum disorder (ASD) can be more stressful and discouraging than parenting a child with typical development, especially during the COVID-19 pandemic. This study aimed to unpack the factors and processes contributing to resilience among parents of children with ASD and the difficulties they faced during the COVID-19 pandemic lockdowns in a City in China (Macau SAR).
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Cross-lagged relations between maternal criticism and emotional and behavioral problems in children with ASD Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-03-01 Paul R. Benson
Few autism studies have examined the ways that family expressed emotion (EE) and its components, particularly parental criticism, affect and are affected by child emotional and behavior problems over time. As such, the primary purpose of this longitudinal study was to examine the direction of effects between maternal criticism and child problem behaviors to assess whether these relationships are predominately
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Social network support is associated with teacher’s perceptions of transition planning for their autistic students Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-03-01 Amanda Dimachkie Nunnally, Heather Nuske, Briana Bronstein, Fernanda Castellon, Jenny C. Chiappe, Consuelo Garcia, Samantha Hochheimer, Hyon Soo Lee, Nicole Sparapani, Sarah Vejnoska, Amber R. Fitzgerald, Lynne Levato, Jennica Li, Felicia Jones, Wendy Shih, Suzannah Iadarola, David S. Mandell, Tristram Smith, Aubyn Stahmer, Sheryl Kataoka, Connie Kasari, Elizabeth McGhee Hassrick
School transitions are accompanied by disruptions in routines and increased social and academic demands, creating challenges for autistic students, who often have difficulty coping with change. These transitions are also challenging for teachers, who often report feeling unprepared to guide their autistic students through the transition process. This study examined teacher and student factors that
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Younger age is associated with better outcomes in autism severity, language, and adaptive skills after one school year in autism special education classes Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-29 Ronit Saban-Bezalel, Ditza A. Zachor, Einat Avni, Esther Ben-Itzchak
A well-accepted hypothesis in the field of autism spectrum disorder (ASD) is that early intervention is crucial for better outcomes. However, research has noted significant variability in early intervention outcomes. This study examined the role of age in relation to outcomes in comprehensive developmental domains following one year of school in community special education classes for ASD. We compared
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A pilot mixed-methods evaluation of an intervention to reduce Korean undergraduates’ stigma toward autistic people Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-27 So Yoon Kim, Kristen Gillespie-Lynch, Wn-ho Yoon
Heightened stigma in South Korea may contribute to the difficulties that autistic undergraduate students experience in college. This study aimed to explore non-autistic Korean undergraduate students’ stigma toward autistic people using semi-structured interviews surrounding a pilot autism anti-stigma training. During the pre-intervention interview, 22 Korean undergraduate students were asked to describe
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Broad autism phenotype traits and self-reported sensory processing across sensory modalities Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-27 Carly A. Yadon, Mary Vonarx
Despite a longstanding connection between sensory processing and autism, sensory processing differences did not become part of the diagnostic criteria for autism spectrum disorder (ASD) until the DSM-5. Emerging research suggests that differences in sensory processing may be related to broad autism phenotype traits in the general population. The present study adds to this literature by including a
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An evaluation of a stepped-care telehealth program for improving the sleep of autistic children Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-26 Monique A.C. Clarke, Laurie K. McLay, Karyn G. France, Neville M. Blampied
Sleep problems are prevalent in Autistic children, adversely affecting their development, well-being and quality of life. Traditional face-to-face behavioral interventions are hindered by accessibility. Using a single-case design, this study evaluated the efficacy of a stepped-care telehealth-delivered behavioral sleep intervention (TDBSI). Seven Autistic children (aged 4–8) and their parents participated
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Self-efficacy as a mediator between involvement in intervention and quality of life in parents of children and adolescents with autism spectrum disorder Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-24 Chiara Fante, Andrea Zagaria, Barbara Dioni, Cinzia Raffin, Francesca Capelli, Tommaso Manari, Vittorio Lenzo, Raffaele De Luca Picione, Alessandro Musetti
Previous studies have suggested that increased parental involvement in intervention for children with autism spectrum disorders (ASD) may be associated with improved parental Quality of Life (QoL). This study investigates the mediating role of parental self-efficacy in the relationship between involvement in intervention and QoL in parents of children and adolescents with ASD. One hundred and eighty-eight
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Social context in stress and autism: comparing physiological profiles across two social paradigms in youth with and without autism spectrum disorder Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-23 Rachael A. Muscatello, Trey McGonigle, Simon Vandekar, Blythe A. Corbett
The social world is often stressful for individuals with autism spectrum disorder (ASD). Research shows youth with ASD demonstrate physiological hyperreactivity to some social stressors (e.g., interaction) but not others (e.g., evaluation); therefore, this study examined diagnosis (ASD or typical development (TD)), social context, perceived anxiety, and physiological responsivity across multiple stress
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Inhibition of purinergic P2 receptors prevents synaptic and behavioral alterations in a rodent model of autism spectrum disorders. Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-23 Lidia Babiec, Anna Wilkaniec, Elżbieta Gawinek, Wojciech Hilgier, Agata Adamczyk
Extracellular nucleotides acting through specific purinergic receptors play a key role in synaptic transmission and neuromodulation. Therefore, any deregulation of purine-dependent signaling may lead to synaptic dysfunction and the development of autism-like behaviors. Here, we used a well-established autism spectrum disorders (ASD) model of a single prenatal exposure to valproic acid (VPA). Wistar
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Therapeutic diets and supplementation: exploring their impact on autism spectrum disorders in childhood – A narrative review of recent clinical trials Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-22 Ruzha Pancheva, Rositsa Chamova, Dimitar Marinov, Albena Toneva, Mariya Dzhogova, Sevdzhihan Eyubova, Natalya Usheva
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by social communication deficits, restricted interests, and repetitive behaviors. Nutritional interventions have gained attention as potential therapeutic strategies for individuals with ASD. This review aims to provide a comprehensive summary of recent clinical trials investigating the effects of various nutritional interventions
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Spatial and identity cues differentially affect implicit learning in Chinese autistic children in the contextual cueing task with human stimuli Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-21 Yu Xie, Hui-Zhong He, Linda R. Watson, Zhi-Han Dong
Autistic children cannot adjust their behaviors in response to environmental social cues as readily as typically developing children. The development of adaptive social behaviors is mainly dependent on the ability to implicitly learn associations or probabilities that are embedded in the environmental cues. Mounting evidence has suggested that autistic individuals have intact implicit learning in contextual
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Factors associated with the job satisfaction of autistic adults Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-12 Shannon Crowley LaPoint
Following high school graduation, autistic adults are more likely to be disengaged from participation in employment opportunities. The autistic individuals who do obtain jobs, often experience lower rates of employment, work fewer hours, and receive less pay when compared to other non-autistic adults. However, few researchers have explored outcomes associated with the satisfaction of autistic people
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“I’m not mad, bad, and dangerous … simply wired differently”: Exploring factors contributing to good quality of life with autistic women Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-12 Arianna Paricos, Alexandra Sturrock, Katherine Twomey, Kathy Leadbitter
There is increasing recognition of under-representation of autistic women in the academic literature and the impact of this on understanding, diagnosis, and support. Previous research has suggested that autistic women have poorer quality of life (QoL) than the general population. However, these findings have been established through use of QoL measures based on non-autistic norms and priorities. This
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Autistic traits in adolescents in psychiatric inpatient care: Clinical and demographic characteristics and correlates Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-08 Jessica M. Schwartzman, Alexandra H. Bettis
Rates of psychiatric hospitalization among adolescents in the United States are rising, with many adolescents presenting to these settings with diverse clinical presentations, including autistic traits. To our knowledge, there has been little research identifying clinical characteristics of adolescents with autistic traits admitted to psychiatric inpatient units, which may be leveraged to improve assessment
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The relationship between alexithymia and self-esteem in autistic adolescents Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-06 Melissa Strang, Caitlin M. Macmillan, Claire M. Brown, Merrilyn Hooley, Mark A. Stokes
Research suggests autistic adolescents experience lower self-esteem and higher cognitive alexithymia than non-autistic adolescents. Heightened cognitive alexithymia has been associated with lower self-esteem in non-autistic adolescents but remains unexamined in autistic populations. This study aimed to examine whether autism diagnosis and alexithymia subscales significantly predicted self-esteem. Data
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A replication and extension of the Cool Kids Autism Spectrum Disorder Anxiety Program: Randomised controlled trial reducing anxiety in autistic adolescents Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-03 Theresa M. Kidd, Rosanna M. Rooney, Trevor G. Mazzucchelli, Kate E. Tonta, Jacob D. Peckover, Robert T. Kane
Autistic adolescents who experience anxiety face unique challenges. Cognitive-behavioural therapy is an evidence-based treatment for anxiety in Autistic children, yet there is less evidence for adaptations of these CBT group interventions for adolescent populations. This study evaluated the efficacy of the Cool Kids Autism Spectrum Disorder Anxiety program in reducing anxiety in Autistic adolescents
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Sleep and daytime functioning in autistic teenagers: A psychological network approach Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-02-02 I.M.G. Schouwenaars, M.J.C.M. Magnée, H.M. Geurts, C.A.M. van Bennekom, S. Pillen, L.J. Waldorp, T.F. Blanken, J.P. Teunisse
Although sleep problems in autistic teenagers are associated with impaired daytime functioning, it remains unclear how sleep and daytime functioning are related. We used a network approach to disentangle patterns between sleep, sleep hygiene, and daytime functioning. Over a three-week period, 31 autistic teenagers answered daily questions about sleep and daytime functioning. Sleep tracker data were
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Impact of child-centered play therapy intervention on children with autism reflected by brain EEG activity: A randomized controlled trial Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-29 Kim-Lui Raise Chan, Guang Ouyang
Research into the effects of child-centered play therapy (CCPT) consistently highlights its positive impact on autistic children. However, its effectiveness at the neural level is underexplored. To address this research gap, the present study investigates the influence of CCPT interventions on autistic children, specifically focusing on measurable changes in brain activity through electroencephalography
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Perceptions of autistic and non-autistic adults in employment interviews: The role of impression management Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-29 Jade Eloise Norris, Jemma Nicholson, Rachel Prosser, Jessica Farrell, Anna Remington, Laura Crane, Laura Hull, Katie Maras
Social communication and interaction differences can make employment interviews particularly challenging for autistic people, who may be less able to modulate their Impression Management (IM). This makes autism a relevant test case of the extent to which behavioral IM influences perceptions of job candidates. Two studies are reported. In Study 1, lay-raters watched a video of autistic and non-autistic
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The impact of parenting stress and cultural orientation on communication skills in minimally verbal children with autism spectrum disorders: A comparative study in India and the US Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-29 Suma Suswaram, Nancy C. Brady, Brian Boyd
Assessing the impact of intrinsic and extrinsic factors on communication skill development in minimally verbal children with Autism Spectrum Disorders (MV-ASD) is crucial, yet limited research exists on cultural variations of these factors. This study explored the associations between parenting stress, cultural orientation, and communication skills in children with MV-ASD from India and the US. Data
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Serum hypoxia-inducible factor-1 alpha (HIF-1α) and apelin levels in children and adolescents diagnosed with autism spectrum disorder Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-25 Esen Yildirim Demirdöğen, Mehmet Akif Akinci, Abdullah Bozkurt, Özgür Esmeray, Fatma Betül Özgeriş, Nezahat Kurt, Neslihan Yüce
Autism spectrum disorder (ASD) is a neurodevelopmental disorder in which underlying etiological factors remains unclear. The important environmental factors associated with ASD, include neuroinflammation, hypoxia, and oxidative stress. HIF-1α and apelin are biochemical markers that play important roles in neuroinflammation, hypoxia and oxidative stress. The aim of this study is to determine whether
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Effects of autistic traits on prosocial tendencies: The chain mediating role of fear of missing out and interpersonal security Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-25 Qin Luo, Hai Li, Yaojie Lin, Rongqing Hu, Hong Li, Shuo Zhao
Increasing evidence suggests that the defining features of autism spectrum disorder are present to varying degrees throughout the general population. Therefore, exploring factors associated with prosocial behavior in individuals with elevated levels of autistic traits may offer valuable insights into both autistic traits and prosocial behavior. In this study, our goal was to determine the relationship
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Gastrointestinal symptoms have a non-temporal association with regression in a cohort with autism spectrum disorder using the simons simplex collection Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-20 Jacob Albers, Adriana Bagos-Estevez, LeeAnne Green Snyder, Athanasios Tsalatsanis, Amelia Boehme, Jennifer M. Bain
Autism spectrum disorder (ASD) can present with developmental regression. In this study, we hypothesize an association between Gastrointestinal (GI) symptoms and regression. We conducted a two-part analysis using data from the Simon Simplex Collection consisting of 2564 ASD probands. Independent sample t-tests or chi-squared tests were utilized comparing regression against no-regression groups, and
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A qualitative study of physical activity drivers in autistic individuals using COM-B. Autistic and non-autistic perspectives Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-18 Katherine Parsons, Simon Payne, Nigel Holt, Joanne Wallace
Background Despite evidence of the health benefits of physical activity in non-autistic populations and the additional benefits for autistic populations, physical activity levels remain stubbornly low in autistic individuals. Understanding the determinants of physical activity is essential in order to support intervention development. Methods The current research applied the Theoretical Domains Framework
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The utilization of psychopharmacological treatments for individuals with autism spectrum disorder (ASD) in a middle-income European country Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-16 Irena Stojanovska, Anirban Chatterjee, Yasir Ahmed Syed, Vladimir Trajkovski
Background Studies examining the utilization of psychopharmacological treatments (psychotropic medications) for autism spectrum disorder (ASD) have primarily been carried out in affluent nations. Nonetheless, there is an evident dearth of data originating from low- and middle-income countries. Our study sought to comprehensively evaluate the usage of psychopharmacological treatments and the effectiveness
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The relationships of autistic child characteristics, metacognitive beliefs, and autistic traits with affiliate stigma among parents of children with autism spectrum conditions: A moderated mediation study Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-18 Yu Ma, Liz Yuanxi Lee, Yuying Wang, Xuemin Zhang
Background Caregivers of children with autism spectrum conditions (ASCs) are typically affected by autism-related stigma, which is internalized to form affiliate stigma. Limited studies have explored the factors potentially associated with affiliate stigma among parents of children with ASC. The present study examined the relationships among autistic child characteristics, parental autistic traits
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Higher autism trait severity in children associates with diminished integration of angry prosody in semantic processing Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-13 Gilbert Ka-Bo Lau, Ming Lui, Andrea Hildebrandt, Werner Sommer, Changsong Zhou
Background Previous studies examined group differences of individuals with and without autism. This study investigated individual differences in automatic integration of emotional prosody during semantic processing at the behavioral and neural levels among children using a continuous measure of autism trait severity. Method Event-related potentials (ERPs) of 46 children, 21 of them diagnosed with ASD
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Autism identity in young adults and the relationships with participation, quality of life, and well-being Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-06 Liron Lamash, Dovrat Sagie, Efrat Selanikyo, Sonya Meyer, Eynat Gal
Background Autism presents self-identity challenges across the lifespan. Like “illness identity,” the degree to which a person integrates chronic illness into their self-identity, autism identity entails unique issues following diagnosis. Accepting the diagnosis allows better coping with its challenges and psychological, social, and physical functioning. However, knowledge of autism identity’s relationship
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Comparing the autism service needs and priorities of Indigenous and newcomer families in Canada: Qualitative insights Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2024-01-06 Vanessa C. Fong, Janet McLaughlin, Margaret Schneider, Grant Bruno
Background Indigenous Peoples and newcomers are two of the largest and fastest growing populations in Canada (Statistics Canada, 2022; Zimonjic, 2022). Yet despite this, little is known about their experiences navigating and accessing autism services for their children. Method To address this gap, the current study sought to explore the autism service needs and priorities of Indigenous and newcomer
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Using the LENA® system for children with autism in educational settings: A comparison with human coders Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-30 Moon Young Savana Bak, Seungwon Chung, Sarah M. Avendaño, Joshua B. Plavnick, Julie S. Brehmer, Amber M. Reilly
Researchers recommend collecting repeated or prolonged natural language samples to supplement direct assessments and anecdotal reports in language studies for autistic children. Several studies have used the Language Environment Analysis® (LENA) system to collect language samples from autistic children. However, there has been little research that investigates the reliability of using the LENA system
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Individual, social, and life course risk factors for experiencing interpersonal violence among autistic people of varying gender identities: A mixed methods systematic review Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-27 Kassandrah Cooke, Kathryn Ridgway, Laura Pecora, Elizabeth Westrupp, Darren Hedley, Merrilyn Hooley, Mark A. Stokes
Background Interpersonal violence is a widespread yet understudied issue in autism spectrum disorder (henceforth, ‘autism’). Characteristic of autism are high rates of gender diversity, and so increased multiple minority group membership. Under minority stress and intersectionality models, minority identity presents greater risk of violence, while demographic variables (e.g., gender, sexuality, race)
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Relationship between perceived discrimination and social anxiety among parents of children with autism spectrum disorders in China: The mediating roles of affiliate stigma and perceived social support Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-26 Sisi Wang, Tianhao Wu, Jingjing Liu, Wenjun Guan
Background Social anxiety among parents of children with autism spectrum disorders (ASD) is a critical issue because it could lead to adverse consequences for psychological and social functioning. Research shows that there is a positive correlation between perceived discrimination and social anxiety. Affiliate stigma and low levels of perceived social support, which may stem from experiences of discrimination
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Maternal multivitamin supplementation is associated with symptoms in offspring with autism spectrum disorder: A multi-center study in China Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-27 Xiujie Qi, Ting Yang, Jie Chen, Li Chen, Ying Dai, Hua Wei, Feiyong Jia, Lijie Wu, Yan Hao, Ling Li, Jie Zhang, Xiaoyan Ke, Mingji Yi, Qi Hong, Jinjin Chen, Shuanfeng Fang, Yichao Wang, Qi Wang, Chunhua Jin, Tingyu Li
Background We aimed to investigate the relationship between maternal vitamin D and multivitamin supplementation during pregnancy and the risk of autism spectrum disorder (ASD) and symptoms in offspring with ASD. Methods This study enrolled 1321 children with ASD and 1200 typically developing (TD) children under 7 years old in China. Maternal vitamin supplements were classified for vitamin D, multivitamin
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Creative performance and attitudes toward creativity in adults with autism spectrum disorder Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-26 Alice Cancer, Sara Schiattone, Martina Monfredini, Alessandro Antonietti, Barbara Colombo
Previous studies have shown contrasting results on the creative skills of adults with autism spectrum disorder (ASD). ASD thinking, which has been reported to often show lower flexibility, has been previously associated with lower scores in creative tasks aimed at measuring the ability to generate a large number of diverse ideas. However, enhanced originality of responses was observed in ASD, mostly
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Caregiver perspectives, experiences and service satisfaction, and health service utilization among families of children with developmental disorders at a tertiary center in a low-resource setting Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-22 Florence N.O. Okwara, Kirsten A. Donald
Background We describe the health perspectives, experiences, and level of service satisfaction among caregivers of children with autism spectrum disorder (ASD) and those with global developmental delays (GDD) attending services at a tertiary paediatric center, and how these influence health services utilization (HSU). Methods In this cross-sectional study, we interviewed caregivers using pre-validated
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Qualitative and quantitative pretend play and their predictors in children with autism spectrum disorder: A path-analysis study Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-20 Yen-Ting Yu, Hsiu-Man Chiu, Chien-Ho Lin, Ching-Lin Hsieh, Kuan-Lin Chen
Children with autistic spectrum disorder (ASD) often have difficulties in both qualitive and quantitative pretend play. Theory of mind (ToM), symptom severity, and verbal comprehension appear to be potential correlates of pretend play. However, the underlying relationships of these correlates to pretend play remain unclear. Therefore, we applied path analysis to explore the relationships among these
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Heart rate variability biofeedback as an anxiety intervention for college students with autism spectrum disorder Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-14 Ryan Coleman, Kayla Trites, Brandon Parker, Nicholas Benson
Background Students with Autism Spectrum Disorder (ASD) attending higher education face an increased risk for the development of anxiety disorders. This can lead to poor academic outcomes, social difficulties, health problems, economic struggles, and other lifelong challenges. Heart Rate Variability Biofeedback Therapy (HRVBT) is a technique with preliminary positive results for the treatment of anxiety
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Trace element levels and autism spectrum disorder in a sample of Algerian children: A case-control study investigation Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-13 Younes Zebbiche, Belkis Stambouli, Imene Kaddour-Benkada, Ahmed Amziane, Akli Islam Chebli, Mohammed Yacine Achouri, Reda Djidjik, Barkahoum Alamir
The prevalence of autism has been increasing in recent years due to better screening. diagnosis. and awareness campaigns. Toxic metals are considered to be one of the environmental factors that may contribute to autism spectrum disorders (ASD). This study aimed to investigate the levels of toxic and essential trace elements in autistic children and their connection to autism. The study included 40
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Interaction between XRN2 mutation and gut microbiota on the risks of autism spectrum disorder Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-13 Haoxue Wang, Quan Zhang, Yanlin Chen, Fang Hou, Kaiheng Zhu, Qi Jiang, Pei Xiao, Zhen Xiang, Xvfang Wu, Yixi Fan, Xinyan Xie, Li Li, Ranran Song
Background The intestinal dysbiosis can be observed in patients with autism spectrum disorder (ASD), partly explained by the alteration in gut microbiota composition. Our study aims to screen ASD causal variants and explore the potential interaction between variants and gut microbiota. Methods We conducted the expression quantitative trait loci (eQTL) analysis to identify variations that regulated
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Iron, magnesium, zinc and selenium - The most common elemental deficiencies in children with autism spectrum disorder Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-08 Katarzyna A. Kaczmarek, Małgorzata Dobrzyńska, Sławomira Drzymała-Czyż
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Examining daily impact of mood and quality of social support for caregivers of children on the autism spectrum Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-05 Mackenzie Robeson, Katey Hayes, Kristina Rossetti Shekouh, Erica Ahlich, Kimberly Zlomke
Background Caregivers of children on the autism spectrum often report elevated levels of perceived stress which may lead to poorer ratings of quality of life (QOL), though this relation has not yet been investigated at the daily level. Caregiver daily mood and quality of social support may buffer the relation of perceived stress to QOL. Method The current study utilizes mobile ecological momentary
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Psychometric properties of the 10-item Autism Quotient in an acute psychiatric sample Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-05 Chloe C. Hudson, Harris E. Bajwa, Courtney Beard, Thröstur Björgvinsson
Purpose Diagnoses of autism spectrum disorder (ASD) are commonly missed among psychiatric patients. As such, a brief screening tool that reliably captures ASD symptoms could help to facilitate access to diagnosis. We evaluated the factor structure, internal consistency, and convergent validity of the 10-item Autism Spectrum Quotient (AQ-10; Allison et al., 2012) in a diagnostically diverse sample of
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Working together: The role of autistic students’ behavioral adjustment in promoting positive parent-teacher relationships Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-05 Lana Andoni, Abbey Eisenhower, Cyanea Y.S. Poon, Kohrissa Joseph, Jan Blacher, Alice Carter
Background Autistic children experience more externalizing and internalizing symptoms relative to non-autistic peers. Higher quality parent-teacher relationships (PTR) may support children’s adjustment. At the same time, higher levels of these mental health difficulties may create a strained relationship between parents and teachers. Therefore, the relation between PTR quality and externalizing or
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Use of standardized motor assessments in children with autism spectrum disorder: A meta-analysis and systematic review Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-06 Maninderjit Kaur, Perman Gochyyev, Devashish Tiwari
Background To summarize and appraise the existing literature on the use of standardized motor assessments in children with Autism Spectrum Disorder (ASD), with a special focus on the trends for administering and reporting standardized results in this population. Methods A thorough literature search was conducted for studies published from 2000 to 2023 on the motor skills of children with ASD using
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A meta-analysis of self-management interventions for students with ASD Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-06 Gretchen Scheibel, Lauren M. Zaeske, Elisabeth J. Malone, Kathleen N. Zimmerman
Background Self-management interventions (SMI) are a broad class of interventions used to teach students to assess, monitor, and adjust their own behavior without direct intervention from an educator. SMI support students with autism spectrum disorder (ASD) to learn valuable self-awareness and self-determination skills for better outcomes in adulthood. Methods A systematic review and meta-analysis
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Relationships between autistic traits, motor skills and socioeconomic status Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-02 Siobhan de Lange, Dee Muller, Chloe Dafkin
Background Autism is a neurodevelopmental condition that presents with social and communicative difficulties as well as restricted or repetitive behaviors. Previous research has highlighted the ubiquity of motor impairments in autistic children, but the relationship between the severity of motor impairment and the degree of autistic traits has not yet been adequately researched. The role of socioeconomic
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Predictive validity and cut-off score of the Mealtime Behavior Questionnaire for children with autism spectrum disorder Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-12-02 Kazuyo Nakaoka, Kiyomi Tateyama, Takuma Yuri, Shun Harada, Shinichi Takabatake
Purpose This study examined the predictive validity of the Autism Spectrum Disorder Mealtime Behavior Questionnaire (ASD-MBQ) and determined the optimal cutoffs to differentiate problematic mealtime behaviors related to autism spectrum disorder (ASD) in children with ASD and non-autistic children in early childhood. Methods The participants were parents/caregivers of children aged 3–6 years. The ASD-MBQ
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A social-competence group intervention featuring didactic teaching and practice in play contexts for preschool children with autism spectrum disorders Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-11-30 Fu-Mei Chiang, Yen-Ting Yu, Ming-Hsuan Liu, Ching-Chiau Kuo, Ching-Lin Hsieh, Kuan-Lin Chen
Background Relatively few intervention programs of social competence have been specifically designed for preschool children with autism spectrum disorders (ASD). This randomized controlled trial (RCT) investigated the effectiveness of the social-competence group intervention (SCGI), which features a combination of didactic teaching and practice in play contexts for preschool children with ASD. Methods
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Social validity of telepractice in families with children with autism Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-11-30 Pau García-Grau, Gabriel Martínez-Rico, Margarita Cañadas, Rómulo J. González-García
This research evaluates the social validity (SV) of Telepractice as an intervention modality in families with children with ASD. The study analyzed the SV perceived by families according to the characteristics of the intervention and service delivery. A total of 168 Spanish families with a child with ASD or developmental delay at risk for ASD receiving support services from 45 centers in 44 cities
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Brief report: Temporal distribution of visual attention between the eyes and mouth in young autistic children Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-11-30 Pauline MAES, Fanny STERCQ, Mikhail KISSINE
Background Face scanning studies in autistic children report mixed results as to attention allocated to the eyes and mouth regions. While face scanning is a dynamic process, the way autistic children distribute their attention between the eyes and mouth of their interlocutor is usually analyzed by averaging the proportion of time spent looking either on the eyes or the mouth over the whole duration
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Omega 3 effects on sleep and body composition in children with autism spectrum disorder: A randomized placebo-controlled trial Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-11-25 Zahra Gohari Dezfuli, Hamideh Salehi, Keivan Karimi, Kurosh Djafarian
Background Sleep disturbances and disruptions in body composition, encompassing factors like fat mass, and lean body mass are common challenges in individuals with autism spectrum disorder (ASD). Despite numerous studies in this field, research has not yet yielded clear and definitive results. Methods In this randomized clinical trial, we investigated the effects of omega-3 supplementation (360 mg
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Remote vs. in-person schooling during the COVID-19 pandemic and internalizing symptoms among children on the autism spectrum Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-11-16 Audrey Courreges, Chrystyna D. Kouros, Naomi V. Ekas, Sam Levy
Background Children on the autism spectrum encountered interruptions to their education due to the COVID-19 pandemic (White et al., 2021). This study examined the extent to which autistic children’s anxiety and depressive symptoms during the pandemic were associated with the school format they attended in October 2020 (remote, in-person/hybrid, homeschool), controlling for their pre-pandemic symptoms
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Preliminary efficacy of a transition training program for autistic adolescents Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-11-17 Sarah A. Schoen, Andrea Valdez
Purpose Young autistic adults experience poor transition outcomes in the area of employment. With reduced opportunities to develop work skills, there are also reduced opportunities for socialization, independence and experiences of success. Thus, there is a need for transition planning programs for autistic adolescents and youth. Method This pilot study employed two complementary methodologies. A non-concurrent
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The experience of anxiety for autistic children and young people: A thematic synthesis review Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-11-17 Claire Neilson, Caroline Bond
Background Anxiety is a commonly co-occurring mental health condition for autistic children and young people. Literature indicates a fractured conceptualisation of the construct of anxiety and measurement tools may be insensitive to unique autistic presentations. The neurodiversity paradigm calls for a shift towards qualitative research methodologies situated within everyday realities. The purpose
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“That he won't experience life like he should”: Exploring worries of family caregivers of transition-age autistic youth Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-11-10 Sarah Balser, Grazia DiPierro, Caroline Duke Chaikin, Rita Obeid, Kristen A. Berg, Karen J. Ishler
Background Caregiver (CG) worry, a dimension of CG burden, has rarely been explored in CGs of transition-aged autistic youth. The present study investigated CG, youth, and service characteristics as potential predictors of CG worry and explored expressed concerns from CGs about their autistic youth and their care. Method Data were drawn from a study of 174 family CGs of transition-age autistic youth
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Preliminary analysis of a clinical trial of children with autism spectrum disorder treated with DHA-rich marine Schizochytrium sp. oil and multi-vitamin/mineral complex Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-11-11 Giuliana Franzago Salmazo, Maria Aparecida Baptista de Oliveira, Fernando Augusto Lima Marson, Juliana Mozer Sciani
Background Autism spectrum disorder (ASD) is a syndrome characterized by alterations in social interaction and communication, frequently associated with stereotyped patterns, such as repetitive behavior. Inflammation and oxidative stress are frequently observed in patients, and natural products that control these aspects can be an alternative for ASD treatment. Method: In this prospective case series
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Examining the feasibility and effectiveness of PEERS for adolescents via telehealth during the COVID-19 pandemic Res. Autism Spectr. Disorder. (IF 3.293) Pub Date : 2023-11-06 Chimei M. Lee, Connor Petricek, Morgan Haga, Samantha Smalley, Katherine Pelletier, Nimco Essa, Rebekah L. Hudock
Background The PEERS program is an evidence-based social skills intervention focusing on skills related to making and keeping friends as well as managing conflict and rejections. Because of the COVID-19 pandemic, social skills interventions have been moving to virtual settings, including PEERS; however, limited research on the feasibility and efficacy of telehealth group therapy has been done. Method