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Use of multisensory stimulation interventions in the treatment of major neurocognitive disorders Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-12-23 Catherine Cheng, Glen B. Baker, Serdar M. Dursun
ABSTRACT OBJECTIVE: Behavioral and psychological symptoms of dementia (BPSD) are a heterogeneous constellation of non-cognitive symptoms and behaviours that can cause significant patient distress and present complex management challenges. Behavioural and pharmacological treatments are used to decrease the symptoms, preserve function and increase quality of life. In the treatment of individuals with
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Adjunct ketamine treatment effects on treatment-resistant depressive symptoms in chronic treatment-resistant schizophrenia patients are short-term and disassociated from regional homogeneity changes in key brain regions – a pilot study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-12-23 Jiaen Ye, Xiaodong Lin, Deguo Jiang, Min Chen, Yanchi Zhang, Hongjun Tian, Jie Li, Chuanjun Zhuo, Yanling Zhao
ABSTRACT BACKGROUND: To investigate the effects of adjunct ketamine treatment on depressive symptoms and brain activity in chronic treatment-resistant schizophrenia (CTRS) patients with treatment-resistant depressive (TRD) symptoms. METHODS: Calgary Depression Scale for Schizophrenia (CDSS), positive and negative syndrome scale (PANSS), and regional homogeneity (ReHo) results were compared before versus
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Validity and reliability study of the Turkish version of the tolerance for mental pain scale-10 Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-12-23 Mehmet Emin Demirkol, Lut Tamam, Zeynep Namlı, Özge Eriş Davul
ABSTRACT OBJECTIVE: Psychological pain has been accepted as one of the most critical psychological risk factors underlying suicidal ideation and behaviour. Suicide is chosen as a way to get rid of intense, painful and unbearable psychological pain. Since the level of tolerance rather than the intensity of psychological pain was considered to be more predictive for suicide, we aimed to investigate the
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Establishing the cut-off scores for the severity ranges of schizophrenia on the BPRS-6 scale: findings from the REAP-AP Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-12-23 Seon-Cheol Park, Eun Young Jang, Kiwon Kim, Hoseon Lee, Joonho Choi, Amitava Dan, Arshad Hussain, Andi Jayalangkara Tanra, Takahiro A. Kato, Kok Yoon Chee, Sih-Ku Lin, Chay Hoon Tan, Afzal Javed, Norman Sartorius, Naotaka Shinfuku, Yong Chon Park
ABSTRACT Objective: Using data from the Research on Asian Psychotropic Prescription Patterns for Antipsychotics (REAP-AP), our study aimed to establish the remission and severity ranges (mild, moderate, and severe) of schizophrenia on the Brief Psychiatric Rating Scale-6 (BPRS-6). Methods: A total of 1,438 patients with schizophrenia from India, Indonesia, Japan, Malaysia, and Taiwan were enrolled
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CNR2 rs2229579 and COMT Val158Met variants, but not CNR2 rs2501432, IL-17 rs763780 and UCP2 rs659366, contribute to susceptibility to substance use disorder in the Turkish population Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-12-03 Selin Kurnaz, Ahmet Bulent Yazici, Ayse Feyda Nursal, Pinar Cetinay Aydin, Ayca Ongel Atar, Nazan Aydin, Zeliha Kincir, Sacide Pehlivan
ABSTRACT OBJECTIVE: Substance use disorders (SUD) are among the most important public health problems throughout the world. We investigated whether COMT (Val108/158Met), CNR2 (rs2501432 and rs2229579), UCP2 (rs659366), and IL-17 (rs763780) gene variants were associated with SUD and its clinical parameters in a Turkish population. METHODS: We conducted a case–control study among 136 subjects with SUD
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Social cognition and emotion regulation may be impaired in adolescents with obesity independent of the presence of binge eating disorder: a two-center study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-11-28 Serkan Turan, Gonca Özyurt, Gönül Çatlı, Yeşim Öztürk, Ayhan Abacı, Aynur Pekcanlar Akay
ABSTRACT Background: Binge eating disorder (BED) and obesity in adolescents is associated with variations in social cognition and emotion regulation. The current study aimed to evaluate the Theory of Mind (ToM) abilities in adolescents with obesity with and without BED and to examine how they related to emotional and psychopathologic evaluations. Methods: One hundred twenty-eight adolescents comprising
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Altered cooperativeness in patients with polycystic ovary syndrome Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-11-25 Erson Aksu, Elmas Beyazyüz, Yakup Albayrak, Nihan Potas, Ferit Durankuş, Gamze Uvaçin, Murat Beyazyüz
ABSTRACT OBJECTIVE: In the present study, we aimed to compare temperament and character traits between patients with polycystic ovary syndrome (PCOS) and age-body mass index-matched healthy controls (HC). We hypothesized that patient with PCOS would differ in terms of temperament and character traits compared with HCs. MATERIAL AND METHODS: Fifty patients who were diagnosed with PCOS and 42 age-body
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Antidepressant-like activities of extracts of the fungus Paecilomyces tenuipes M98 Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-11-19 Yaying Li, Long Han, Tong Lu, Muhammad Noman, Weidong Qiang, Xinxin Lan, Tingting Gao, Jinnan Guo, Xiaomei Zhang, Haiyan Li, Jing Yang, Linna Du
ABSTRACT Objective: Depression is an disease that seriously endangers the physical and mental health of human body. However, in view of the limitation of existing antidepressants, it's urgent to find new antidepressants from natural products. The aim of this study was to evaluate the effect of Paecilomyces tenuipes, which is an important entomogenous fungus in China. Methods: This research was intent
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The psychometric properties of the Generalized Anxiety Disorder scale (GAD-7) among Korean university students Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-11-18 Boram Lee, Yang Eun Kim
ABSTRACT OBJECTIVE: The seven-item Generalized Anxiety Disorder scale (GAD-7) is a practical self-report measure that screens for the severity of Generalized Anxiety Disorder in primary care. Previous studies have shown that the GAD-7 is theoretically sound, but the results regarding its psychometric properties have been somewhat inconsistent with both adult and student samples. Despite these findings
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Automatic thoughts, cognitive distortions, dysfunctional attitudes, core beliefs, and ruminative response styles in unipolar major depressive disorder and bipolar disorder: a comparative study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-11-18 Nurgul Yesilyaprak, Sedat Batmaz, Mesut Yildiz, Emrah Songur, Esma Akpinar Aslan
ABSTRACT OBJECTIVES: We aimed to compare patients with bipolar disorder and major depressive disorder, who were either in an acute depressive episode or in remission, and a healthy control group on their cognitions related to depression and mania/hypomania, and on their response styles. METHODS: A total of 300 participants who presented to our outpatient psychiatry department were included in the study
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Association between emotional functioning and biological rhythm disruptions in patients with schizophrenia Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-11-04 Cigdem Sahbaz, Ayse Kurtulmus
ABSTRACT Objective: Dysregulation of biological rhythm is associated with reduced executive functioning and potentiating psychosis, which are essential for the Theory of Mind (ToM) among patients with schizophrenia. However, the association between cognitive dysfunction, emotional information and disruption of biological rhythm remains uncertain. Methods: Forty-one patients with schizophrenia and forty
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Effect of Ferritin on Short-Term Treatment Response in Attention Deficit Hyperactivity Disorder. Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2016-11-08 Pinar Oner,Ozgur Oner,Esra Cop,Kerim M Munir
OBJECTIVES Several studies have shown that iron deficiency and ferritin levels are associated with parent and teacher Attention Deficit Hyperactivity Disorder (ADHD) ratings. Although there are conflicting results, it has also been reported that iron supplementation may help to decrease ADHD symptoms. When all these previous studies are taken into account, it is clear that a large study investigating
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Effects of maternal symptom ratings and other clinical features on short-term treatment response to OROS methylphenidate in children and adolescents with ADHD in a naturalistic clinical setting. Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2016-10-18 Esra Cop Tasgin,Ozgur Oner,Pinar Yurtbasi,Kerim Munir
OBJECTIVE To investigate the effect of Attention Deficit Hyperactivity Disorder (ADHD), antisocial behavior and anxiety/depression ratings of mothers, and child and adolescents' age, gender, ADHD subtype, and comorbidity on one-month drug treatment response to OROS methylphenidate in ADHD in a naturalistic setting. METHODS The analyses included 223 subjects (191 boys, 32 girls; age 6-15 years, mean:
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Distinctive clinical correlates of hazardous drinking Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-10-18 Ok-Jin Jang, Seon-Choel Park, Se-Hoon Kim, Sung-Young Huh, Ji-Hoon Kim
ABSTRACT The present study was conducted to identify clinical correlates of hazardous drinking (HD). The data were derived from the Korean Research for Development of Alcohol Addiction Diagnosis and Assessment System. Variable measurement were personal characteristics, lifetime alcohol use history, Motivational Structure Questionnaire for alcoholics, Alcohol Outcome Expectancies Scale, and Alcohol
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Syrian Civil War’s effects on Turkish school children: prevalence and predictors of psychopathology Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-10-15 Sinem Tabur, Ali Evren Tufan, Veysi Çeri, Bengi Semerci
ABSTRACT Objectives: The Syrian Civil War forced millions into asylum in neighbouring countries. Refugees/asylum seekers have elevated risk for psychopathology with the most important being post-traumatic stress disorder (PTSD). Subjective experiences and symptoms of the hosting populations which have also experienced similar traumas have received relatively little attention up to now. We aimed to
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Early effects of selective serotonin reuptake inhibitors (SSRIs) on cornea and lens density in patients with depression Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-10-11 Yalçın Karaküçük, Abdullah Beyoglu, Aysegül Çömez, Fatma Özlem Orhan, Merve Demir
ABSTRACT PURPOSE: To investigate the effects of SSRIs on cornea and lens density, intraocular pressure (IOP) and anterior chamber parameters, including anterior chamber volume (ACV), anterior chamber depth (ACD), corneal volume (CV) and central corneal thickness (CCT), in patients with depression during a three-month follow-up period. METHOD: In this prospective study, 31 total patients, who were prescribed
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Thymoquinone (TQ) demonstrates its neuroprotective effect via an anti-inflammatory action on the Aβ(1–42)-infused rat model of Alzheimer's disease Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-10-11 Birsen Elibol, Sule Terzioglu-Usak, Merve Beker, Cigdem Sahbaz
ABSTRACT OBJECTIVES: Alzheimer’s disease (AD) is a severe neurodegenerative disease with presentation of the neuronal death, memory loss and cognitive decline. The relationship between neuroinflammation and AD has been well documented. However, the options of anti-inflammatory treatment are very limited in patients with AD. Previous studies showed that flavonoids might be an effective treatment and
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Pregabalin abuse among patients with opioid use disorders may increase the severity of withdrawal symptoms: a single-center, case-control study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-10-09 Özlem Çıtak Ekici, Volkan Şahiner, Gamze Erzin, Davut Ocak, Şafak Yalçın Şahiner, Erol Göka
ABSTRACT OBJECTIVE: Opioid addiction is a disease that is increasing in our country, Turkey, and around the world, which it is difficult to treat in medical, social, and economic terms. Pregabalin is a preparation used for the treatment of epilepsy, neuropathic pain, and anxiety disorders. In opioid users, pregabalin is increasingly being self-administered off-label due to its euphoria effect at high
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Antineuronal antibodies and 8-OHdG an indicator of cerebellar dysfunction in autism spectrum disorder: a case–control study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-10-03 Fethiye Kilicaslan, Hamza Ayaydin, Hakim Celik, Meryem Ozlem Kutuk, Hasan Kandemir, Ismail Koyuncu, Adnan Kirmit
ABSTRACT Objectives: Autism spectrum disorder (ASD) is a neurodevelopmental disorder, that starts in early childhood and presents with deficiencies in social-communicational domains along with restricted and repetitive behaviours/interests. While genetic factors are dominant in its pathogenesis, many factors, including neurological, environmental and immunological have been identified. Furtheremore
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Is restless legs syndrome related with depression/anxiety disorders or medications used in these disorders? A cross-sectional, clinic-based study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-10-03 Davut Ocak, Vahap Ozan Kotan, Salih Cihat Paltun, Makbule Çiğdem Aydemir
ABSTRACT Objective: The aim of this study is to investigate the frequency and severity of restless legs syndrome (RLS) in patients diagnosed with depression or anxiety disorder and the relationship of RLS with medications used in these disorders and clinical/sociodemographic characteristics of the patients. Methods: Four hundred and fifty-four consecutive patients who were treated with medication for
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Comparison of the groups treated with mirtazapine and selective serotonine reuptake inhibitors with respect to birth outcomes and severity of psychiatric disorder Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-10-03 Buket Belkız Güngör, Nalan Öztürk, Ayça Öngel Atar, Nazan Aydın
ABSTRACT Objective: The literature provides very limited information on mirtazapine usage in the pregnancy period. The groups including pregnant women who used SSRI or mirtazapine as a single treatment, SSRI–mirtazapine combination treatment and unmedicated groups were compared with respect to illness severity and birth outcomes. Method: The study sample included 120 pregnant women; 40 women with SSRI
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Efficacy and acceptability of three prolactin-sparing antipsychotics in patient with schizophrenia: a network meta-analysis Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-09-27 Jianjie Huang, Min Chen, Ce Chen, Xiaodong Lin, Deguo Jiang, Yonghui Zhang, Lina Wang, Chuanjun Zhuo, Hongjun Tian, Chenyuan Du
ABSTRACT Background: The present study aimed to systematically evaluate three prolactin-sparing antipsychotics for treating schizophrenia. Methods: We performed a meta-analysis of three prolactin-sparing antipsychotics in patients with schizophrenia. Endpoints of interest were the Positive and Negative Syndrome Scale (PANSS), Brief Psychiatric Rating Scale (BPRS), Clinical Global Impressions-Severity
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Reliability, validity, and factorial structure of the Turkish version of the Freiburg Mindfulness Inventory (Turkish FMI) Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-09-13 Hasan Turan Karatepe, Kaasım Fatih Yavuz
ABSTRACT OBJECTIVES: Mindfulness is the awareness that emerges through paying attention on purpose, in the present moment, and nonjudgementally to the unfolding of experience moment to moment. Mindfulness-based interventions are frequently used in clinical situations and in establishing psychological well-being in a non-clinical sample as psychological techniques. Therefore, many mindfulness measures
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Aripiprazole as a treatment option for delusional parasitosis: case series of 8 patients Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-08-31 Meltem Çınar, Pelin Kutlutürk, İrem Ekmekçi Ertek, Behçet Coşar
ABSTRACT OBJECTIVE: Delusional parasitosis (DP), also known as Ekbom’s Syndrome, is a rare, generally monosymptomatic disorder that characterizes with the fixed belief of being infected by parasites without any evidence of medical or microbiological proof. These patients are examined in dermatology and infection clinics with symptoms and signs of pruritus, skin and subcutaneous scars secondary to itching
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The relationship between oxytocin, vasopressin and atrial natriuretic peptide levels and cognitive functions in patients with schizophrenia Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-08-16 Tugba Mutu Pek, Esra Yazici, Derya Guzel, Elif Kose, Ahmet Bülent Yazıcı, Atila Erol
ABSTRACT Objective: The aim of this study was to investigate the relationship between oxytocin (OXT), vasopressin (AVP) and atrial natriuretic peptide (ANP) levels and cognitive functions in schzophrenia as well as to compare the findings to those in healthy controls. Method: Patients with chronic schizophrenia and (n=63) healthy controls (n=60) were evaluated with the Rey Auditory Verbal Learning
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The effects of childhood emotional abuse on aggressive obsessions among patients with obsessive compulsive disorder may be mediated by symptoms of depression and anxiety Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-07-22 Ayşegül Kart, Hakan Türkçapar
ABSTRACT OBJECTIVE: The purpose of this study was to evaluate the relationship between childhood traumas (CTs) and severity and symptom dimensions of Obsessive Compulsive Disorder (OCD). METHOD: One hundred and sixty (160) patients diagnosed with OCD were included. The Yale-Brown Obsessive-Compulsive Scale (YBOCS), the Childhood Trauma Questionnaire (CTQ), the Beck Depression Inventory (BDI), and the
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Validity and reliability of the Turkish version of the knowledge about childhood autism among health workers questionnaire Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-07-11 Börte Gürbüz Özgür, Hatice Aksu, Erhan Eser
ABSTRACT Objective: The aim of this study is to present the psychometric properties of the Turkish version of the knowledge about childhood autism among health workers (KCAHW) questionnaire. Methods: Three hundred fifteen primary health care facility workers and 28 child and adolescent mental health professionals were enrolled in this study. Participants filled out socio-demographic data forms and
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Bipolar disorder and perceived social support: relation with clinical course, and the role of suicidal behaviour Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-07-10 Ozlem Kazan Kizilkurt, Ferzan Ergun Giynas, Medine Yazici Gulec, Hüseyin Gulec
ABSTRACT Objective: The objective in this study was to analyse the effects of the perceived social support from the family, friends and other important people in the lives of patients with bipolar disorder(BD) in remission on clinical course and suicidal behaviour in a multidimensional model. Method: The study conducted 100 patients diagnosed with BD-1(remission) according to DSM-5. All participants
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The effects of atomoxetine on weight, height, and body mass index in Turkish children and adolescents with attention deficit hyperactivity disorder Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-07-09 Serkan Turan, Aynur Pekcanlar Akay
ABSTRACT Background: We aimed to examine the long-term effects of atomoxetine on height, weight, and body mass index in Turkish children and adolescents with attention deficit hyperactivity disorder (ADHD). Methods: Participants (6–18 years, 146 boys, 52 girls) with ADHD who used atomoxetine for at least 1 year were included in a retrospective study. Weight, height, and BMI z scores were converted
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The effects of focused ultrasound pulsation of nucleus accumbens in opioid-dependent rats Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-07-09 Erdem Deveci, Alperen Kılıç, Onur Yılmaz, Aynur Nabi, Arif Sanlı Ergün, Ayhan Bozkurt, Ayşe Kurtulmuş, Ahmet Öztürk, Mukaddes Eşrefoğlu, Mehmet Şerif Aydın, Ebru Şahan, İsmet Kırpınar
ABSTRACT Background: Deep Brain Stimulation (DBS) is the only modality proven to be effective on selective stimulation of the deep brain structures. It was previously reported that, by using DBS, stimulation of nucleus accumbens (NA), a region that plays a pivotal role in the pathogenesis of substance addiction, is effective for the treatment of substance addiction. Objective: The purpose of the current
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Body image, depression and eating behaviour: a comparative study in eating disordered women and healthy controls Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-07-04 F. Elif Ergüney Okumuş, H. Özlem Sertel Berk, Başak Yücel
ABSTRACT OBJECTIVE: The aim of this study is to compare eating behaviours, body image, and depressive symptoms in eating disordered women with a demographically matched healthy control sample to evaluate the predictors of eating behaviour. METHODS: 150 women (75 in the Eating Disorders Group-EDG and 75 in Healthy Control Group-HCG) participated in the study. All participants completed the Eating Disorder
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Retinal nerve fiber layer, macular thickness and anterior segment measurements in attention deficit and hyperactivity disorder Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-06-30 Taha Ayyildiz, Didem Ayyildiz
ABSTRACT AIM: We aimed to explore whether there is difference in terms of Retinal Nerve Fiber Layer (RNFL) thickness, macula thickness and anterior segment structures of the eye between children and adolescents with ADHD and healthy controls. METHOD: Children and adolescents aged 8–16 years who were admitted to the Child Psychiatry outpatient clinic of Ahi Evran University Hospital diagnosed with ADHD
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Neurodevelopmental and growth follow-up of the baby exposed to antipsychotics during pregnancy and lactation: a case report Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-06-13 Ömer Faruk Uygur, Hilal Uygur
ABSTRACT Clozapine is an antipsychotic drug for the treatment-resistant schizophrenia. Although clozapine is superior to other antipsychotics, it is less common in psychiatric prescriptions due to clozaphobia. Little is known about the use of clozapine during pregnancy and lactation, or its effect on the mother, foetus and baby. Pregnancy category of clozapine is considered to be of relatively reliable
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Establishing the cut-off score for aggression on the Brief Psychiatric Rating Scale-Excited Component (BPRS-EC) in schizophrenia patients Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-06-04 Seon-Cheol Park, Eun Young Jang, Gyung-Mee Kim, Ajit Avasthi, Sandeep Grover, Andi Jayalangkara Tanra, Takahiro A. Kato, Kok Yoon Chee, Mian-Yoon Chong, Afzal Javed, Chay Hoon Tan, Norman Sartorius, Naotaka Shinfuku, Yong Chon Park
ABSTRACT OBJECTIVE: We aimed to present the scalability and cut-off score for the presence of aggression on the Brief Psychiatric Rating Scale-Excited Component (BPRS-EC) in schizophrenia patients. METHODS: From the Research on Asian Psychotropic Prescription Patterns for Antipsychotics, 1,438 Asian patients with schizophrenia were recruited in present study. The Mokken analysis was used to evaluate
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Comparison of long-term efficacy and safety of blonanserin treatment in individuals with first-episode and relapsed schizophrenia: a 3-year retrospective study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-06-04 Lyang Huh, Bong Ju Lee
ABSTRACT Purpose: The objective of this retrospective chart review study was to evaluate the long-term efficacy and tolerability of blonanserin treatment in individuals with schizophrenia. Patients and methods: We collected data from 28 (56%) antipsychotic-naïve subjects with first-episode (FE) schizophrenia and 22 subjects with relapsed schizophrenia treated with blonanserin. We investigated psychiatric
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Processing speed may improve earlier than response inhibition/ interferens in children with ADHD-combined type receiving methylphenidate: a single-center study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-05-21 Fatih Hilmi Çetin, Hasan Ali Güler, Sevde Afife Ersoy, Serhat Türkoğlu
ABSTRACT OBJECTIVES: The aim of this study was to determine the order of improvement in response inhibition, interference capacity, and processing speed in the Stroop test after starting methylphenidate treatment in children with ADHD. METHODS: This study included a total of 52 children aged 7–16 years who were diagnosed with combined-type ADHD for the first time and who began to use methylphenidate
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Parent-reported social problems and clinician-evaluated adverse effects may be differentially affected by differing extended release methylphenidate formulations: a prospective, naturalistic study from Turkey Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-05-03 Merve Cikili Uytun, Fatih Hilmi Çetin, Zehra Babadağı
ABSTRACT OBJECTIVE: Medikinet retard® is a nonosmotic, extended-release formulation of Methylphenidate (MPH) and has been used in Turkey for the last 4–5 years. The aim of our study is to compare the efficacy on functionality of Medikinet retard® and Concerta® and their adverse events. METHODS: Participants were referred to the Kayseri Training and Research Hospital and followed up there between August
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Evaluation of depression comorbidity in obstructive sleep apnea syndrome Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-04-25 Şule Şirin Berk, Sema Baykara
ABSTRACT BACKGROUND: Diagnosis and treatment of the comorbid depression in patients with obstructive sleep apnea syndrome could be effective on the reduction of morbidity and mortality. OBJECTIVES: The present study aimed to investigate the depression comorbidity in OSAS patients grouped by Apnea-Hypopnea Index (AHI). However, the previous studies on the presence of depression in OSAS reported inconsistent
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Patients without psychopathology applying for aesthetic rhinoplasty may display elevated harm avoidance and reduced self-directedness: a cross-sectional, case–control study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-04-16 Mehmet Gurkan Gurok, Faruk Kılıç, Sema Sağlam, Neşe Göçer Gürok, M. Murat Kuloğlu, Alpagan M. Yıldırım
ABSTRACT Objective: The present study was intended to compare the body image, self-esteem, temperament and character traits of a group of patients who applied for aesthetic rhinoplasty with healthy controls subjects. Methods: Thirty patients who applied the Plastic, Reconstructive and Aesthetic Surgery Clinic at the Fırat University Hospital for aesthetic surgery were included in the present study
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Social functioning and its association with accompanying psychiatric symptoms in adolescents with anorexia nervosa Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-03-21 Bilge Merve Kalaycı, Kevser Nalbant, Devrim Akdemir, Sinem Akgül, Nuray Kanbur
ABSTRACT OBJECTIVE: This study aimed to investigate social functioning and its relation to associated psychiatric symptoms and disorders in adolescent girls with anorexia nervosa. METHODS: Thirty-two adolescent girls with anorexia nervosa aged between 12 and 18 years were compared to a control group of 30 adolescent girls without any psychiatric disorder. The Schedule for Affective Disorders and Schizophrenia
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Emotion dysregulation and internalizing symptoms affect relationships between ADHD symptoms and borderline personality features among male patients with substance use disorders Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-03-20 Cuneyt Evren, Vahap Karabulut, Izgi Alniak, Bilge Evren, Ozlem Helin Carkci, Hanife Yilmaz Cengel, Pelin Ozkara Menekseoglu, Turan Cetin, Muge Bozkurt, Gokhan Umut
ABSTRACT OBJECTIVES: The aim of the present study was to evaluate the relationship of borderline personality features (BPFs) with attention-deficit/hyperactivity disorder (ADHD) symptoms among male patients with substance use disorder (SUD) and to evaluate the impact of emotion dysregulation on this relationship. We also wanted to control the effects of depression and state anxiety. METHOD: Participants
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Neurological deficits and comorbidity in children with reading disorder Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-03-18 Sajida Naz, Najma Najam
ABSTRACT OBJECTIVES: Neuropsychological deficits were compared between three groups, i.e. RD (n = 12), RD (ADHD) (n = 12), and control group (n = 24) on neuropsychological tasks assessing Visuoconstructional ability, Postural Stability, and Language Laterality. METHODS: Forty-eight children (age M = 12.5 years; 29 females, 19 males) were selected through purposive sampling procedure, from local primary
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Secretagogin may not be a new neuroendocrine biomarker in schizophrenia while levels may reflect clinical severity Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-03-14 Gamze Erzin, Canan Topçuoğlu, Şenol Bayram, Hasan Karadağ, Güven Ozkaya, Turan Turhan, Erol Göka
ABSTRACT OBJECTIVE: Schizophrenia is a neurodegenerative and neurodevelopmental disorder. For this reason, it is important to determine the level of markers that are neuroprotective and have been altered in other neurodegenerative diseases in inspecting the etiology of schizophrenia. Secretagogin (SCGN), is a member of Calcium (Ca) binding proteins and thought to have a neuroprotective effect. In this
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Oxidative stress and inflammatory response in patients with psoriasis; is there any relationship with psychiatric comorbidity and cognitive functions? Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-03-12 Erdem Deveci, Tuba Kocacenk, Ebru Şahan, Onur Yılmaz, Ahmet Öztürk, İsmet Kırpınar
ABSTRACT Objectives: Psoriasis is a chronic, inflammatory skin disease which has been linked to psychopathology. Oxidative stress and inflammation are associated with atherogenesis and neuronal stress thus, cognitive functions might be impaired in psoriasis patients. We aimed to compare psychiatric comorbidity, neurocognitive functions, oxidative stress and inflammatory cytokine levels in psoriasis
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Depression and anxiety have unique contributions to somatic complaints in depression, irritable bowel syndrome and inflammatory bowel diseases Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2019-03-08 Ömer Yanartaş, Haluk Tarik Kani, Ayşe Sakallı Kani, Zeynep Nur Demirok Akça, Erdoğdu Akça, Serhat Ergün, Neslihan Tezcan, Özlen Atug, Neşe İmeryüz, Kemal Sayar
ABSTRACT OBJECTIVE: In this study we aim to investigate the effects of somatic and related symptoms (SARS), alexithymia, hypochondriasis, anxiety and depression on patients with major depressive disorder, irritable bowel syndrome, inflammatory bowel disease which are the representative diseases of brain gut axis (BGA). METHOD: Sex and age similar groups of participants with major depressive disorder
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L-methylfolate in patients with treatment resistant depression: fulfilling the goals of personalized psychopharmacological therapy Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-12-04 Samet Kose, Kemal Sayar
(2018). L-methylfolate in patients with treatment resistant depression: fulfilling the goals of personalized psychopharmacological therapy. Psychiatry and Clinical Psychopharmacology: Vol. 28, No. 4, pp. 359-362.
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Behavioural and psychological symptoms of Alzheimer’s disease associated with caregiver burden and depression Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-11-09 Gamze Bozgeyik, Derya Ipekcioglu, Menekse Sıla Yazar, Mehmet Cem Ilnem
ABSTRACT OBJECTIVE: The aim of the study was to investigate the relationship between behavioural and psychological symptoms of Alzheimer’s disease with caregiver burden and depression. METHODS: In this prospective and clinic-based study, 71 patients over 65 years of age diagnosed with Alzheimer's disease according to DSM IV diagnostic criteria who were admitted to Bakirkoy Prof. Dr. Mazhar Osman Research
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The effects of the triple P-positive parenting programme on parenting, family functioning and symptoms of attention-deficit/hyperactivity disorder. A randomized controlled trial Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-11-03 Öztürk Yusuf, Özyurt Gonka, Akay Pekcanlar Aynur
ABSTRACT OBJECTIVES: This is the first study to evaluate the efficacy of parent training in attention-deficit/hyperactivity disorder (ADHD) in Turkey. The aim of this study was to evaluate the effectiveness of the positive parenting programme (Triple P) on ADHD symptoms, functionality, severity of disease, and behavioural and emotional problems of children. An additional aim was to evaluate the potential
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Resilience and personality in psychiatric inpatients Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-11-02 Güler Acar Sivri, Feride Ezgi Ünal, Hüseyin Güleç
ABSTRACT OBJECTIVE: The aim of this study was to identify relationships between the concept of resilience and the psychobiological model that treats the dimensions of temperament and character as representative of innate and environmental factors, respectively, among psychiatric inpatients whose diseases have acquired chronicity. METHODS: The study involved 171 psychiatric inpatient volunteers. The
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Levels of endocannabinoid metabolizing enzymes are not related with BDNF levels in patients with schizophrenia: a case-controlled study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-10-31 Mehmet Cemal Kaya, Mahmut Bulut, İbrahim Kaplan, Mehmet Gunes
ABSTRACT PURPOSE: While the pathogenesis of schizophrenia has yet to be fully clarified, a huge amount of data suggests the involvement of endocannabinoid system and neurotrophic factors in schizophrenia. Nevertheless, only a very limited number of studies have investigated these two systems together. With this disease containing various unknowns, our primary aim was to simultaneously investigate the
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Development of self-stigma inventory for patients with schizophrenia (SSI-P): reliability and validity study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-10-13 Mustafa Yıldız, Fatma Kiras, Aysel İncedere, Fatma Betül Abut
ABSTRACT OBJECTIVES: Internalizing the public stigma in patients with schizophrenia leads to self-stigmatization associated with a number of negative consequences such as depression, low self-esteem, hopelessness, impairment of social adaptation, unemployment, and treatment non-adherence. No instruments have been developed to assess the self-stigmatization for patients with schizophrenia living in
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Turkish validity and reliability of the Sexual Complaints Screener for Women Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-09-25 Anıl Gündüz, Rayka Kumru Bayazit, İbrahim Gündoğmuş, Sencan Sertçelik, Hatice Gönül, Alişan Burak Yaşar, Gülay Oğuz, Mehmet Zihni Sungur
ABSTRACT OBJECTIVE: The Sexual Complaints Screener for Women (SCS-W) is a brief, practical and up-to-date scale which assesses sexual problems parallel with the current diagnostic manuals. The SCS-W consists of 10 questions which assess a variety of sexual dysfunctions and potential distress experienced at the time of and the last six months leading to the evaluation. This study aims to assess the
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Childhood physical neglect may impair processing speed in adults with ADHD: a cross-sectional, case–control study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-09-19 Zeynep Baran Tatar, Alparslan Cansız
ABSTRACT AIM: Higher rates of childhood trauma have been reported in both children and adults with adult attention deficit hyperactivity disorder (ADHD) than in healthy individuals. The association between childhood trauma and deficiency in cognitive functions in adults has been reported. One of the aims of our study was to compare childhood trauma reporting between adults with ADHD and healthy individuals
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Psychiatric pharmacogenomics in the age of neuroscience: promises and challenges Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-09-12 Samet Kose, Mesut Cetin
(2018). Psychiatric pharmacogenomics in the age of neuroscience: promises and challenges. Psychiatry and Clinical Psychopharmacology: Vol. 28, No. 3, pp. 231-235.
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Attention deficit hyperactivity disorder and anti-Purkinje autoantibodies: no link? Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-09-11 Fatih Hilmi Cetin, Feyza Cetin, Yasemen Isik, Esra Guney, Feyza Alp, Altan Aksoy
ABSTRACT OBJECTIVES: Attention Deficit Hyperactivity Disorder (ADHD) is a neurobehavioral disorder that begins in early childhood, and many factors play role in its etiology. Many studies have been conducted to identify the causes of ADHD, but the exact factors are still unknown. Although cerebellar dysfunction in the etiology of ADHD was shown in different studies, the possible causes of dysfunction
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Personality and subjective psychiatric symptoms of parents of obese youth: a controlled study Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-08-27 Gonca Özyurt, Gönül Çatlı, Gülten Cingöz, Bumin Nuri Dündar, Aynur Akay Pekcanlar, Ayhan Abacı
ABSTRACT OBJECTIVE: In this study, it was aimed to evaluate the relationship between parental personality characteristics and psychiatric symptoms with childhood obesity. METHODS: This cross-sectional study was conducted in third-level clinical care institution. Thirty obese adolescents and 29 age- and sex-matched healthy controls were included in the study. Both mothers and fathers were accepted to
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Perinatal Anxiety Screening Scale validiy and reliability study in Turkish (PASS-TR validity and reliability) Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-08-23 Esra Yazıcı, Tugba Mutu Pek, Hilal Uslu Yuvacı, Elif Köse, Serhan Cevrioglu, Ahmet Bulent Yazıcı, Ali Savaş Çilli, Atila Erol, Nazan Aydın
ABSTRACT BACKGROUND: Anxiety disorders are common in women. This sensitivity extends into the perinatal period as well. Thus, screening for anxiety disorders during the aforementioned period is important for the proper management and treatment of conditions. This study was conducted to assess the validity and reliability of the Perinatal Anxiety Screening Scale, which was determined to be beneficial
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Turkish validity and reliability of the sexual complaints screener for men Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-08-08 Anıl Gündüz, Sencan Sertçelik, İbrahim Gündoğmuş, Meliha Zengin Eroğlu, Rayka Kumru Bayazit, Hatice Gönül, Alişan Burak Yaşar, Mehmet Zihni Sungur
ABSTRACT OBJECTIVE: To evaluate the validity and reliability parameters of the Turkish version of the Sexual Complaints Screener for Men (SCS-M) which is a promising brief measure to assess sexual problems in daily practice. METHODS: A cross-sectional study was conducted online. Data was collected through an online validated and content specific questionnaire via self-reporting. In total, 230 male
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A qualitative study on corporal punishment and emotionally abusive disciplinary practices among mothers of children with ADHD Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-08-06 Ş. Gülin Evinç, Dilşad Foto Özdemir, Ferda Karadağ, Devrim Akdemir, Tülin Gençöz, Özlem Sürücü, Fatih Ünal
OBJECTIVES The present study aimed to investigate actual disciplinary behaviours of Turkish mothers’ in the context of relational environment and to investigate ADHD as a risk factor on abusive disciplinary practices. METHODS Totally 120 children (children with ADHD; study group and healthy controls; control group) – and their mothers were interviewed with this aim. The interviews were qualitatively
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Psychiatric evaluation of juvenile delinquents under probation in the context of recidivism Psychiatry Clin. Psychopharmacol. (IF 0.7) Pub Date : 2018-08-06 Onur Tugce Poyraz Fındık, Ayşe Rodopman Arman, Nesrin Erturk Altınel, Emine Guliz Durlanık, Hanefi Ozbek, Bengi Semerci
ABSTRACT OBJECTIVE: High rates of psychiatric disorders and comorbidities have been reported in the juvenile justice system, and both phenomena are thought to contribute to repetitive offending. Although extensive research on the prevalence of psychiatric disorders in juvenile offenders has been conducted in European countries and the USA, epidemiological research concerning this issue is limited in