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Ultrasound and X-ray guided prenatal embolization of massive chorioangioma J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-22 Aurélie Morvan, Jérôme Soussan, Kathia Chaumoître, Claude D'Ercole, Pierre Castel
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Early-onset neonatal sepsis: Effectiveness of classification based on ante- and intrapartum risk factors and clinical monitoring J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-21 Laurie Dalut, Anne Brunhes, Sébastien Cambier, Denis Gallot, Karen Coste
In 2017, the French public health authority HAS published new guidelines for the management of newborns at risk of early bacterial neonatal infection. These guidelines were based on ante- and intrapartum risk factors and clinical monitoring. In January 2021, we implemented a new protocol based on these guidelines in our tertiary maternity unit. To assess the impact of the protocol implemented on neonates’
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Clinical and biological factors associated with red blood cell transfusion during severe postpartum haemorrhage – A single-center retrospective cohort study J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-21 Cravassac Lauren, Hamadmad Rayan, Crequit Simon, Redel Diane, Yakhou Leila, Verton Caroline, Haddad Bassam, Lecarpentier Edouard
Red blood cell (RBC) transfusions are of utmost importance in the management of severe post-partum haemorrhage. Although the recommendations for blood transfusion protocols are regularly issued, there are significant differences in management depending on the context and the medical teams involved. To determine during the first 24 h, the clinical and biological factors associated with the decision
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Organization and quality of care in childbirth in private for-profit maternity units in France: Risks of the deprofessionalization of midwives J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-20 Carine Vassy, Priscille Sauvegrain, Catherine Deneux-Tharaux
In France, in 2007–2009, the risk of peripartum maternal mortality, especially the one due to hemorrhage, was higher in the private for-profit maternity units than in university maternity units. Our research, a component of the MATORG project, aimed to characterize the organization of care around childbirth in these private clinics to analyze how it might influence the quality and safety of care. We
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Enhanced recovery after surgery (ERAS) for deep infiltrating endometriosis surgery: experience of a French center. J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-19 Sara Djemouai, Aubert Agostini, Sandrine Loubière, Pascal Auquier, Nicolas Pirro, Antoine Netter, Audrey Pivano
The objective of the study was to evaluate the implementation of an ERAS programme for deep pelvic endometriosis (DPE) surgery in terms of length of stay (LOS), postoperative complications (POC) and rehospitalisation rate. This was a comparative retrospective monocentric study in the Gynaecologic Department of the La Conception Hospital in Marseille, France. We compared a ‘conventional’ group, with
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Digital versus speculum insertion of Foley catheter for labor induction: A systematic review and meta-analysis of randomized controlled trials J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-19 Saeed Baradwan, Majed Saeed Alshahrani, Rayan AlSghan, Hussein Sabban, Khalid Khadawardi, Mohammad Alyafi, Bandr Hafedh, Nada M. Alayed, Zaky Ftouh Rashed, Faiza Ahmed Abdel-Hakam, Mohamed Nasser Elshabrawi, Ahmed Mohamed Abdelhakim, Walaa Elsayed Ahmed
To compare Foley catheter insertion by digital blind method to its placement with a sterile speculum in women with unripe cervix for induction of labor. A systematic search was conducted in Cochrane Library, PubMed, Web of Science, and Scopus databases for randomized clinical trials (RCTs) from inception to July 2023. Included studies compared digital to speculum placement of the Foley catheter for
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Maternal and neonatal outcomes of French prospective multicenter cohort study COVIPREG during the first two COVID-19 waves J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-16 Alexandre J. Vivanti, Camille Couffignal, Jeanne Sibiude, Anne-Gael Cordier, Vassilis Tsatsaris, Flore Rozenberg, Odile Launay, Alexandra Benachi, Daniele De Luca, Pierre-Yves Ancel, Estelle Marcault, Yves Ville, Julie Carrara, Dominique Luton, Marc Dommergues, Constance Borie, Gilles Kayem, Laurence Lecomte, Marianne Leruez-Ville, Claire Périllaud-Dubois, Valérie Biran, Pauline Manchon, Olivier Picone
SARS-CoV-2 infection on pregnant women was the subject of many questions since the COVID-19 pandemic. We aim to assess maternal and neonatal outcomes of SARS-CoV-2 infection contracted during 2nd and 3rd trimesters of pregnancy during the first two COVID-19 waves across a prospective French multicenter cohort study. Patients were included between April 2020 and January 2021 in 10 maternity hospitals
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Endometriosis: Age at diagnosis and the severity of the disease J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-11 Aurélie Comptour, Claire Figuier, Bruno Pereira, Pauline Chauvet, Nicolas Bourdel, Michel Canis
Endometriosis is often described as a progressive disease beginning with menarche and menstrual bleeding. However, this is controversial, as the origin of the disease remains unknown. The objective of this study was to investigate the association between the severity of endometriosis and age at initial diagnosis. This prospective multicenter cohort study included 964 patients, newly and histologically
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Erratum to “The challenge of defining women at low-risk for childbirth: analysis of peripartum severe acute maternal morbidity in women considered at low-risk according to French guidelines.” [Journal of Gynecology Obstetrics and Human Reproduction 52 (2023) 102551] J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-02 Anne Alice Chantry, Pauline Peretout, Coralie Chiesa-Dubruille, Catherine Crenn-Hébert, Françoise Vendittelli, Camille Le Ray, Catherine Deneux-Tharaux, EPIMOMS study group
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Maintenance oxytocin in the immediate postpartum period: Frequency, determinants and practices in a tertiary maternity unit J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-01 Inès Aubenas, Lyn Badra, Clara Rollet, François Goffinet, Camille Le Ray, Yoann Athiel
To prevent post-partum haemorrhage (PPH), national and international guidelines recommend the administration of a prophylactic injection of oxytocin after all vaginal births. Although additional maintenance oxytocin is not recommended in the immediate postpartum, its administration is quite common (30 % of French births in 2021). To assess in a single center, the frequency and determinants associated
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Association between polycystic ovarian syndrome and incompetent uterine cervix: A systematic review and meta-analysis J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-01 Sindhu Sekar, Sujeewa Fernando, Srividhya Budithi
We aimed to determine the association between polycystic ovarian syndrome (PCOS) and cervical incompetence (CI). We hypothesise that insulin resistance induces a glucose metabolism disorder that could potentially cause cervical incompetence, resulting in an adverse outcome. We conducted a systematic review and meta-analysis of observational studies to summarise the evidence regarding the strength of
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Effects of endometrial versus non-endometrial suturing on isthmocele development; a randomized controlled trial. J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-01 Şener Gezer, Ayşe Seda Daryal, Lale Aksoy
Incomplete healing after cesarean section (CS) can result in isthmocele formation. When suturing the uterus, fully folding the wound lips may embed the endometrial layer into the myometrium, leading to isthmocele development. Hence, this study aimed to compare the effects of endometrial and non-endometrial suturing on isthmocele development. This randomized controlled trial included 274 patients. Women
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Safety and efficacy of pelvic arterial embolization for primary postpartum hemorrhage in hemodynamically stable and hemodynamically unstable patients: Is it “time” for a paradigm change? J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-03-01 Chang Ryul Park, Jeong Gu Nam, Jong Hwa Lee, Jae Cheol Hwang, Sang Hun Lee
Pelvic artery embolization (PAE) is an effective and safe technique for treating postpartum hemorrhage (PPH) with hemodynamic stability. However, its use in hemodynamically unstable patients remains controversial. To determine the safety and efficacy of pelvic arterial embolization (PAE) according to the hemodynamic state of primary postpartum hemorrhage (PPH) patients. This cohort study was conducted
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Impact of breast surgical procedure on survival in BRCA mutated patients with invasive breast cancer: Mastectomy versus conservative treatment J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-29 Katia Mahiou, Clémentine Jankowski, Laura Vincent, Hélène Costaz, Marie-Martine Padeano, Ariane Mamguem, Sandrine Dabakuyo, Charles Coutant
Patients with BRCA1/2 mutations have a higher risk of developing breast cancer compared to the wild-type population. For patients with a BRCA mutation, there are no specific recommendations for surgical management. The aim of this study was therefore to retrospectively investigate overall survival (OS) and recurrence-free survival (RFS) of BRCA mutated patients with localized invasive breast cancer
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Incidence, prognostic factors, and a nomogram of cervical cancer with lung metastasis: A SEER-based study J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-24 Yuping Shan, Zhaoxia Ding, Aiping Chen, Zicheng Cui
The purpose of this study was to investigate the incidence, survival and prognostic factors of cervical cancer with lung metastasis at the initial diagnosis and to develop a visual nomogram to predict the prognosis of these patients. We used the Surveillance, Epidemiology and End Results (SEER) database to screen patients diagnosed with cervical cancer from 2010 to 2015. After strict inclusion and
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Comparison of 3D and 2D laparoscopy: Initial experience of perioperative outcomes and clinical assessment J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-22 Li Yang, Guosen Bu, Jing Zhao, Xiaolin La, Cailing Ma
This study was designed to compare three-dimensional (3D) laparoscopy and conventional two-dimensional (2D) laparoscopy in surgical performance and clinical assessment during laparoscopic radical hysterectomy with pelvic lymphadenectomy (LRHND) for treating early-stage cervical cancer. In this study, we included 67 consecutive patients underwent LRHND for treating early-stage cervical cancer by the
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Teaching principles of electrosurgery to OBGYN trainees via simulation: A hands-on approach J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-22 Nicole Massad, Julian Gingold, Osaro Obanor, Veronica Lerner
Surgeons use electrosurgery daily, though most of them are unfamiliar with its basic safety principles. We have designed a hands-on simulation session to teach OBGYN trainees principles of electrosurgery with practical implications for safety in the operating room. 15 participants completed post-session surveys. Our experience of serially refining teaching materials and electrosurgery demonstrations
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Prevalence of COVID-19 among pregnant women and its impact on childbirth in March 2021: Data from the French National Perinatal Survey J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-22 Olivia Anselem, Caroline Charlier, Nolwenn Regnault, Katiya Madji, Nathalie Lelong, Camille Le Ray, Collaborators - Members of the ENP2021 Study Group, Camille Le Ray, Nathalie Lelong, Hélène Cinelli, Béatrice Blondel, Nolwenn Regnault, Virginie Demiguel, Elodie Lebreton, Benoit Salanave, Jeanne Fresson, Annick Vilain, Thomas Deroyon, Philippe Raynaud, Sylvie Rey, Khadoudja Chemlal, Nathalie Rabier-Thoreau
Several series reported obstetric complications among pregnant women hospitalized for COVID. These data, because they focused on women with the most severe presentations or with specific immunosuppression, were likely to overestimate the risks associated with the infection at a global level. To date, population-based studies, most of which collected data from registers of women hospitalized during
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Ultrasound-guided suction curettage followed by cervico-isthmic placement of foley threeway catheter for cesarean scar pregnancy's treatment. Retrospective study J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-16 Valerio Carletti, Veronica Yacoub, Paola Lopizzo
Cesarean scar pregnancy (CSP) is a rare dangerous condition with still no consensus on standard treatment. Suction curettage has been used as the first-line treatment for CSP with controversial outcomes. This study evaluates efficacy of ultrasound-guided suction curettage (UGSC) followed by cervical-isthmic placement of silicon semirigid three-way foley catheter. This study included 24 women with CSP
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Corrigendum to “Increased chemokine ligand 26 expression and its involvement in epithelial-mesenchymal transition in the endometrium with adenomyosis” [Volume 52, Issue 9 (2023) 102645] J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-15 Ai Ikebuchi, Mitsuhiko Osaki, Ikumi Wada, Hiroki Nagata, Kei Nagira, Yukihiro Azuma, Futoshi Okada, Tasuku Harada, Fuminori Taniguchi
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Usefulness of early morphological ultrasound in association with cell-free DNA testing in case of atypical serum markers in first trimester of pregnancy: a retrospective study over 5 years. J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-15 Noémie Claudel, Olivia Anselem, Charlotte Buron-Fouque, Laila El Khattabi, Christelle Laguillier-Morizot, Pénélope Jordan, Vassilis Tsatsaris, Jean Guibourdenche, Yoann Athiel
Early morphologic ultrasound, generally carried out in case of atypical first trimester serum markers (PAPP-A and/or free hCGβ <0.30 MoM), has not been re-evaluated since the possibility of performing a cell-free fetal DNA analysis in this indication. Our objective was to evaluate the usefulness of early morphological ultrasound in case of atypical profile of serum markers performed in association
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NLRP3 concentration, oxidants, and antioxidants in plasma of endometriosis patients undergoing treatment with dienogest J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-11 Marziyeh Ajdary, Abolfazl Mehdizadeh Kashi, Roya Derakhshan, Shahla Chaichian, Kobra Tahermanesh, Mehdi Mehdizadeh, Sara Minaeian, Azam Govahi
NOD-like receptor pyrin domain-containing 3 () is a cytosolic multi-protein complex that induces inflammation and is negatively regulated by progesterone. Previous researches have reported abnormal induction of reactive oxygen species (ROS) and progesterone resistance in endometriosis (EM). Since progesterone regulates ROS level and, consequently, inflammation, our objective is to investigate whether
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An update on oncofertility in prepubertal females J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-09 Pegah Rashidian
Cancer is a life-threatening event for pediatric patients. Treatment advancements in pediatric cancer have improved prognosis, but some of these treatments have gonadotoxic potential and may affect fertility in different ways. Due to the growing interest of the research community in the life prospects of young cancer survivors, there has been a demand to intersect reproductive medicine and oncology
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Factors associated with successful balloon catheter labor induction in women with a previous caesarean section: A retrospective single-center evaluation J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-09 Louise Ghesquière, Cyril Bengler, Elodie Drumez, Damien Subtil, Véronique Houfflin-Debarge, Sébastien Insubri, Charles Garabedian
Labor induction of women with a history of uterine scarring is an increasingly frequent situation and one for which there are currently no clear professional recommendations favoring one method over another. The objectives of this study were to determine the success rate of balloon catheter induction in women with a history of caesarean section and to evaluate the main factors associated with vaginal
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Could the presence and proportion of three/multiple pronuclei (3PN/MPN) zygotes indicate the cytoplasmic maturation state of oocyte cohort in conventional IVF patients? J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-07 Hui-tian Wang, Jing Gao, Jianping Ou, Hai-yang Li, Ping-ping Hong, Yi-min Shu, Tao Li
Although abnormally fertilized zygotes with three or multiple pronuclei (3PN/MPN) are commonly believed to be associated with improper maturation of the oocyte cytoplasm in conventional IVF cycles, no studies investigated the association between the proportion of MPN zygotes and the maturation state of the oocyte cohort. We compared the cytoplasmic maturity of oocytes from conventional IVF cycles with
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Metastatic Profiles and Survival Differences Between Infiltrating Ductal Carcinoma and Infiltrating Lobular Carcinoma in Invasive Breast Cancer J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-02 L. CAVALLER, C. GOUPILLE, F. ARBION, A. VILDE, G. BODY, L. OULDAMER
In this study, we conducted a comprehensive evaluation of metastatic profiles and survival outcomes in patients with infiltrating ductal carcinoma (IDC) and infiltrating lobular carcinoma (ILC) treated at our university hospital center. We collected and analyzed data from all patients diagnosed with invasive breast cancer at our center between January 1, 2007, and 31 December, 2014. We specifically
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Rate of residual tumor after repeat surgery for positive margins in ductal carcinoma in Situ, and predictive factors J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-02-02 Tiphaine Coma, Julien Mancini, Séverine Puppo, Aubert Agostini, Xavier Carcopino
To evaluate the rate of residual tumor in re-excision specimen of patients with positive margins in ductal carcinoma in situ (DCIS) following breast-conservative surgery, and to identify predictive factors of residual tumor. We conducted a monocentric, retrospective study, from January 2010 to December 2020. All 103 patients who underwent re-excision for positive margins in DCIS following breast-conservative
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Extreme prematurity: factors associated with perinatal management and morbi-mortality in western Normandy, France J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-01-26 Pauline Goupille, Quentin Rollet, Ludovic Prime, Cénéric Alexandre, Patricia Dolley, Michel Dreyfus
Background Extreme prematurity (birth before before 26 weeks of gestation), presents complex challenges and can lead to various complications. Survival rates of extremely preterm infants are lower in France than in other countries. The choice between active and palliative care is decisive in managing these births. Objective To conduct an observational study focused on factors associated with perinatal
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Delayed diagnosis and treatment of adolescents and young women with suspected endometriosis J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-01-26 Boris Beloshevski, Miriam Shimshy-Kramer, Matar Yekutiel, Orna Levinsohn-Tavor, Neta Eisenberg, Noam Smorgick
Study objective Early diagnosis and treatment of endometriosis in adolescents and young women is considered essential for improving their quality of life and for prevention of long-term complications. In adult women with endometriosis, significant delays in diagnosis and medical or surgical treatment have been described. Our study aimed to investigate the delay in diagnosis and treatment of adolescents
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Impact of an e-learning training for interpreting intrapartum fetal heart rate monitoring to avoid perinatal asphyxia: A before-after multicenter observational study J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-01-24 Aziz SLAOUI, Cécile CORDIER, Emilie LEFEVRE-MORANE, Véronique TESSIER, François GOFFINET, Camille LERAY, Agnès BOURGEOIS-MOINE, Jeanne SIBIUDE, Anne-Charlotte LAURENT, Elie AZRIA
Introduction Perinatal asphyxia, a condition that results from compromised placental or pulmonary gas exchange during the birth process, is rare but can lead to serious neonatal and long-term consequences. The visual analysis of cardiotocography (CTG) is designed to avoid perinatal asphyxia, but its interpretation can be difficult. Our aim was to test the impact of an e-learning training program for
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Relationship between ultrasound placenta thickness at second trimester and neonatal birthweight: A short research study J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-01-17 Jeremy Boujenah, Olivier Chanelles, Eric Guillo, Alexandre Bouhanna, Fatiha Guennas
Abstract not available
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Percutaneous cryoablation of symptomatic uterine adenomyomas: Initial experience J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-01-17 Clément Marcelin, Jean-Luc Brun, Julie Caprais, Isabelle Molina-Andreo, Eva Jambon, Yann Le Bras, Claude Hocké, Nicolas Grenier
Objective To assess the efficacy and safety of percutaneous image-guided cryoablation of adenomyomas Material and Methods Five symptomatic women who wanted to preserve their uterus and fertility underwent a single session of percutaneous image-guided cryoablation of adenomyoma. Three to six 17-gauge cryoprobes were introduced percutaneously into the adenomyoma under ultrasound and laparoscopy guidance
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Do women with suspected endometriosis benefit from pelvic examination to improve diagnostic and management strategy? J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-01-14 Yohann Dabi, Arnaud Fauconnier, Christine Rousset-Jablonski, Arounie Tavenet, Anne-Cécile Pizzofferrato, Xavier Deffieux
Objective To analyze the literature and expose best evidence available regarding the benefit of pelvic examination for women with suspected endometriosis Methods the AGREE II and GRADE systems for grading scientific evidence. Results Endometriosis is characterized by the heterogeneity in its clinical presentation with many different symptoms reported by patients. In the literature, questioning for
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Melatonin and ovarian tissue transplantation: Current frontiers in research J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-01-12 Lingyun Xie, Yan Ding, Xuyin Zhang
The progress achieved in anticancer therapy in recent years has been paralleled by an increase in the survival of women with cancer globally. Nonetheless, the gonadotoxic impact of anticancer drugs has led to ovarian failure in treated women. While there are documented cases of successful ovarian tissue transplants resulting in restored fertility and childbirth, challenges persist, including suboptimal
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Discoid excision for colorectal endometriosis associated infertility: A balance between fertility outcomes and complication rates J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-01-09 Yohann Dabi, Lea Ebanga, Amélia Favier, Kamila Kolanska, Anne Puchar, Aude Jayot, Clément Ferrier, Cyril Touboul, Sofiane Bendifallah, Emile Darai
Objective The objective of our study was to study the impact of discoid excision for deep endometriosis (DE) with colorectal involvement on fertility outcomes. Methods 49 patients with a desire for pregnancy treated with discoid excision for colorectal endometriosis in our endometriosis expert center between January 2015 and August 2020 were selected from our prospectively maintained database. Indications
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Quality of information and decision regrets during fertility-sparing management for atypical hyperplasia and endometrial cancer in a prospective cohort study J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2024-01-05 Marie Grenot, Tineke Vandenbroucke, Margot Bucau, Martin Koskas
Objective To evaluate satisfaction with information, treatment, and decision regret during management to preserve fertility for atypical hyperplasia (AH) or endometrial cancer (EC). Methods A cohort study with standardized management using chlormadinone acetate was established through a national referral centre between January 2013 and November 2019. During this period, a questionnaire was given to
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Improvement of endometriosis patient's care in a day-hospital setting J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-12-31 Pierre Collinet, Geraldine Giraudet, Ingrid Tiberghien, Elodie Chaumontet, Emilie De Smedt, Margherita Renso
Abstract not available
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Assessing the external validity and clinical relevance of umbilical doppler resistance index references in daily practice J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-12-29 Simon Crequit, Gilles Grangé, François Goffinet, Aude Girault
Objective To assess the external validity and clinical relevance of current references for umbilical artery resistance index (UA RI) in daily practice. Methods Retrospective cross-sectional single center study including all UA RI measurements between 22 and 40 gestational weeks (GW) from distinct patients between 2014 and 2022. Patients with normal pregnancies and normal neonatal outcomes that had
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Manuscript: Evaluation of labor management practices during spontaneous labor J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-12-29 Charlotte Voisin, Johan Pacelli, Audrey Fels, Florence Eboue, Elie Azria
Introduction In 2017, the French national authority for health issued national guidelines to support physiologic labor and reduce medical interventions. This study's primary aim was to evaluate the association between the publication of these guidelines and the vaginal delivery rate in a type IIb perinatal center. The secondary objectives were to evaluate the implementation of these guidelines, their
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PGT and deferred embryo transfer: Is blastocyst biopsy more effective than cleaved embryo biopsy? J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-12-28 Nathalie Arroja, Olivier Binois, Laetitia Hesters, Charlotte Sonigo, Sophie Monnot, Julie Steffann, Nelly Frydman, Anne Mayeur
Objective Blastocyst biopsy has recently been implemented in our laboratory for PGT with a “freeze all” indication. The aim of this study is to compare PGT results between embryos biopsied at the cleaved and embryos biopsied at the blastocyst stage. Study design This is a retrospective cohort study conducted from January 2017 to December 2022 in France. All couples with a “freeze all” indication the
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Delayed umbilical cord clamping in elective and nonelective term Cesarean delivery J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-12-23 Liina Lummevaara, Maija-Riitta Ordén, Anu Mykkänen, Leea Keski-Nisula
Background Delayed cord clamping (DCC) is recommended for preterm and term neonates, regardless of delivery mode. After impression of increased maternal blood loss following DCC implementation during Cesarean delivery (CD) concerns arose about maternal safety, particularly in term CDs. Materials and methods We conducted a retrospective cohort study by reviewing birth records from our tertiary hospital
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vNOTES hysterectomy using the lateral window technique in case of a ventrofixed uterus following previous cesarean sections: A video article J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-12-23 Solène Géry, Alexis Gromez, Jean-Baptiste Thoumas, Patrice Crochet, Sophia Braund
vNOTES uses the vagina as the surgical channel for endoscopy and achieves improved cosmesis compared to conventional laparoscopy as there are no abdominal incisions. Ventrofixation of the uterus to the abdominal wall following previous cesarean sections further adds to the surgeon's concern of bladder injury. In such cases, a modification of the technique is proposed: introducing the vNOTES port first
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Evaluation of pre-therapeutic imaging work-up in the staging of endometrial cancer: Interest in a systematic second opinion in a cancer center J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-12-22 Pawan Baijnath, Margaux Pelissier, Nassim Sahki, Philippe Henrot
Rationale and objectives To evaluate the interest of a systematic second opinion in quality assessment and FIGO staging in the pretherapeutic imaging work-up. Materials and methods A retrospective observational study was conducted on 156 patients who underwent surgery for endometrioid cancer in our institution. 42 % had their initial MRI scans performed in expert centers (University Hospital and Cancer
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Investigating the medical journey of endometriosis-affected women: Results from a cross-sectional web-based survey (EndoVie) on 1,557 French women J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-12-12 Mathilde Bourdon, Chloé Maignien, Géraldine Giraudet, Jean-Philippe Estrade, Emilie Indersie, Céline Solignac, Elisangela Arbo, Horace Roman, Charles Chapron, Pietro Santulli
Objective To investigate the medical journey and the quality of life of French endometriosis-affected women, from the onset of the symptoms to the therapeutic management. Study design Between January 15th 2020 and February 3rd 2020, a prospective cross-sectional web-based survey was conducted among women diagnosed with endometriosis. The questionnaire included 52 questions distributed in five sections
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Margin status after loop electrosurgical excision procedure (LEEP) and laser excision in patients with high-grade cervical neoplasia J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-12-06 Juliette Mosseri, Louise Benoit, Meriem Koual, Huyen-Thu Nguyen-Xuan, Enrica Bentivegna, Anne-Sophie Bats, Henri Azaïs
Introduction Early management of high-grade cervical intraepithelial neoplasia is one of the key steps in cervical cancer prevention after vaccination and screening. It relies on lesion removal by surgical excision, and the French National Cancer Institute (INCa) in 2016 recommend using a loop electro excision procedure (LEEP). However, the laser excision method seems to be as effective with similar
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Abortion medical management between 14−16 weeks’ amenorrhea after French legislation deadline extension J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-11-25 Hortense Carpentier, Jérôme Delotte, Pierre-Alexis Gauci
Background The National French Assembly promoted a law in 2022 allowing an extension of the period of abortion up to 16 week's amenorrhea. Medication protocols vary internationally, and there are no French data on medical management between 14- and 16-weeks’ amenorrhea. Objective To assess effectiveness and feasibility of a medical management abortion between 14 and 16 weeks of amenorrhea. Study design
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Impact of molecular genotyping on the diagnosis and treatment of human chorionic gonadotropin-producing tumors J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-11-29 M Peyle, M Massoud, S Patrier, L Gaillot-Durand, G Side, M Devouassoux-Shisheboran, J Massardier, P Descargues, A Msika, T Hajri, P Rousset, J Haesebaert, JP Lotz, M Jamelot, B You, F Golfier, L Eiriksson, F Allias, PA Bolze
Objectives To assess the use of molecular genotyping to accurately diagnose and treat human chorionic gonadotropin (hCG)-producing tumors and to evaluate the discriminating capacity of molecular testing on prognosis and overall survival. Methods We conducted a retrospective descriptive study of patients registered with the French Reference Center for Trophoblastic Disease between 1999 and 2021. We
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Clinical use of Indocyanine green fluorescence method for sentinel lymph node biopsy in breast cancer in France in 2021 J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-11-29 Louise Benoit, Axelle Gillet de Thorey, Manuel Gomes David, Henri Azais, Enrica Bentivegna, Huyen-Thu Nguyen-Xuan, Vanille Simon, Guillaume Achen, Anne-Sophie Bats, Meriem Koual
Introduction Indocyanine green (ICG) for axillary sentinel lymph node (SLN) detection in early breast cancer is at least equivalent to radioisotopic and/or colorimetric techniques. This procedure has not yet been recommended by learned societies in France. Following the recent drug approval of Infracyanin ® in this indication, we wished to study the use of ICG in France. Methods We conducted a web-based
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Effects of virtual reality on pain during intrauterine device insertions: A randomized controlled trial J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-11-25 Inès Benazzouz, Céline Bouhnik, Anthony Chapron, Maxime Esvan, Vincent Lavoué, Tiffany Brun
Objectives The trial aimed to compare the pain perceived by women during intrauterine device (IUD) insertion, with or without virtual reality (VR) therapy. Furthermore, anxiety during the insertions, pain after the insertions, and satisfaction with the insertions were compared. Methods The trial was designed as a prospective, bi-centric, randomized, open-label interventional trial. All adult women
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Case Report of an exceptional spontaneous abdominal heterotopic pregnancy with superfetation: Diagnosis and treatment: Heterotopic pregnancy with superfetation (8+1 WG & 5+4 WG) J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-11-25 A. JULIEN, A-S. GREMEAU, S. CAMPAGNE-LOISEAU, B. CHAUVEAU, P. CHAUVET, L. COMBET, M. CANIS
Heterotopic pregnancy is an extremely rare condition in which an intrauterine and an extrauterine pregnancy co-exist. In spontaneous conceptions, heterotopic pregnancy occurs in only 1/30 000 pregnancies. The treatment of heterotopic pregnancy must be as minimally invasive as possible to preserve the development of the intrauterine pregnancy. Superfetation, defined as the coexistence of 2 or more foetuses
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Mastectomies for breast cancer: Comparison between peri-operative morbidity after simple mastectomy or after immediate breast reconstruction in a unicentric serie of 210 patients J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-11-22 Sybille Delenne, Charles-André Philip, Isabelle Guimont, Julie Bienstman, Alain-Ali Mojallal, Marion Cortet
Background In breast cancer surgery, IBR (immediate breast reconstruction) is widely proposed to patients without indications of adjuvant treatments and without risk factors of surgical complications. New INCa's guidelines (2022) allow the expansion of IBR indications. Objective A retrospective, unicentric and safety study: post-operative complication rate after IBR in comparison with simple mastectomy
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Higher risk of preterm twin delivery among shorter nulliparous women J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-11-21 Teresinha Simões, Inês Pereira, Laura Gomes, Sofia Brás, Isabel Nogueira, Alexandra Queirós
Objective To determine if maternal height in nulliparous women influences pregnancy results in twin pregnancies. Material and methods Retrospective cohort analysis evaluating twin pregnancies followed at Centro Hospitalar Universitário Lisboa Central, between 1995 and 2020. Of the 2900 pregnancies followed in that period, 886 nulliparous women with dichorionic twin pregnancies were selected. Two groups
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Favipiravir does not appear to be a major teratogen: Case series from Türkiye J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-11-19 Berna Özen, Zeynep Us, Aylin Toplu, Caner Vizdiklar, Yasemin Selalmaz, Yekta Çulpan, Zehranur Turgan Aşik, Mert Kaşkal, Büşra Nazli Açikgöz, Medine Gülçebi Idriz Oğlu, Atila Karaalp, Filiz Onat, Hasan Raci Yananli, Rezzan Gülhan
Introduction Favipiravir has gained attention during the Coronavirus Disease-2019 pandemic due to its potential antiviral effect against Severe Acute Respiratory Syndrome Coronavirus-2. Favipiravir has been identified as a teratogen in animal studies, but there is limited human data. We aimed to evaluate the pregnancy outcomes of women exposed to favipiravir during the pandemic. Material and methods
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Impact of Caesarean section on pregnancy outcomes in ART after transfer of one or more frozen blastocysts J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-11-17 Marie-Sophie David, Emmanuelle Vintejoux, Florentin Kucharczak, Sophie Brouillet, Nathalie Rougier, Stéphanie Huberlant
Introduction The prevalence of Caesarean delivery is rising steadily worldwide, and it is important to identify its future impact on fertility. A number of articles have been published on this subject, but the impact of Caesarean section on reproductive outcomes is still under debate, and none of these articles focus exclusively on frozen blastocysts. Objective The aim of this study was to evaluate
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Ectopic pregnancy adjacent to iliac vessels managed successfully by minimally invasive treatment using local methotrexate injection: An extremely rare case and literature review J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-11-04 Jin Huang, Xin Zuo, Yaoxiang Sun, Xiaoyun Wu, Hongdi Zhu, Wei Cui
A case report of successfully treated retroperitoneal ectopic pregnancy (REP) is presented. A 36-year-old woman, gravida 3, para 2, was admitted to hospital for suspected ectopic pregnancy with light vaginal bleeding and mild abdominal pain for 3 days at 45 days of gestation by the last menstrual period.Multiple transvaginal ultrasonography and two times laparoscopic probes led to the diagnosis of
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Assisted reproductive technology in France: The reproductive rights of LGBT people J. Gynecol. Obstet. Hum. Reprod. (IF 1.9) Pub Date : 2023-10-31 Mikaël Agopiantz, Matthieu Dap, Elena Martin, Larissa Meyer, Alexandre Urwicz, Romane Mougel, Hélène Malmanche
Background In 2021, France authorized ART with sperm donor for female couples and single women. Objectives We summarize here the possibilities of ART among LGBT people in France to date, pointing out the main restrictions for LGBT reproductive rights, requiring future legislative changes. Results Despite the latest modification of the French bioethics laws which notably opens ART to female couples